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Items: 10


Noncoding regions are the main source of targetable tumor-specific antigens.

Laumont CM, Vincent K, Hesnard L, Audemard É, Bonneil É, Laverdure JP, Gendron P, Courcelles M, Hardy MP, Côté C, Durette C, St-Pierre C, Benhammadi M, Lanoix J, Vobecky S, Haddad E, Lemieux S, Thibault P, Perreault C.

Sci Transl Med. 2018 Dec 5;10(470). pii: eaau5516. doi: 10.1126/scitranslmed.aau5516.


Immunogenic stress and death of cancer cells: Contribution of antigenicity vs adjuvanticity to immunosurveillance.

Bloy N, Garcia P, Laumont CM, Pitt JM, Sistigu A, Stoll G, Yamazaki T, Bonneil E, Buqué A, Humeau J, Drijfhout JW, Meurice G, Walter S, Fritsche J, Weinschenk T, Rammensee HG, Melief C, Thibault P, Perreault C, Pol J, Zitvogel L, Senovilla L, Kroemer G.

Immunol Rev. 2017 Nov;280(1):165-174. doi: 10.1111/imr.12582. Review.


Exploiting non-canonical translation to identify new targets for T cell-based cancer immunotherapy.

Laumont CM, Perreault C.

Cell Mol Life Sci. 2018 Feb;75(4):607-621. doi: 10.1007/s00018-017-2628-4. Epub 2017 Aug 19. Review.


The Summit for Cancer Immunotherapy (Summit4CI), June 26-29, 2016 Halifax, Canada.

Wouters MCA, Laumont CM, Chen B, Han SJ, Matuszewska K, Potts K, Boudreau JE, Krawczyk CM.

Cancer Immunol Immunother. 2017 Jun;66(6):811-818. doi: 10.1007/s00262-017-1996-9. Epub 2017 Apr 13. No abstract available.


Global proteogenomic analysis of human MHC class I-associated peptides derived from non-canonical reading frames.

Laumont CM, Daouda T, Laverdure JP, Bonneil É, Caron-Lizotte O, Hardy MP, Granados DP, Durette C, Lemieux S, Thibault P, Perreault C.

Nat Commun. 2016 Jan 5;7:10238. doi: 10.1038/ncomms10238.


Meeting report--9th IRIC International Symposium on Molecular Targets in Cancer Genomics.

Laumont CM, Haberl D, Ghugari R, Tsao S.

J Cell Sci. 2015 Oct 1;128(19):3521-4. doi: 10.1242/jcs.179051.


The nature of self for T cells-a systems-level perspective.

Granados DP, Laumont CM, Thibault P, Perreault C.

Curr Opin Immunol. 2015 Jun;34:1-8. doi: 10.1016/j.coi.2014.10.012. Epub 2014 Nov 15. Review.


Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides.

Granados DP, Sriranganadane D, Daouda T, Zieger A, Laumont CM, Caron-Lizotte O, Boucher G, Hardy MP, Gendron P, Côté C, Lemieux S, Thibault P, Perreault C.

Nat Commun. 2014 Apr 9;5:3600. doi: 10.1038/ncomms4600.


Rejection of leukemic cells requires antigen-specific T cells with high functional avidity.

Vincent K, Hardy MP, Trofimov A, Laumont CM, Sriranganadane D, Hadj-Mimoune S, Salem Fourati I, Soudeyns H, Thibault P, Perreault C.

Biol Blood Marrow Transplant. 2014 Jan;20(1):37-45. doi: 10.1016/j.bbmt.2013.10.020. Epub 2013 Oct 23.


MHC I-associated peptides preferentially derive from transcripts bearing miRNA response elements.

Granados DP, Yahyaoui W, Laumont CM, Daouda T, Muratore-Schroeder TL, Côté C, Laverdure JP, Lemieux S, Thibault P, Perreault C.

Blood. 2012 Jun 28;119(26):e181-91. doi: 10.1182/blood-2012-02-412593. Epub 2012 Mar 21.

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