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Items: 8


RING finger nuclear factor RNF168 is important for defects in homologous recombination caused by loss of the breast cancer susceptibility factor BRCA1.

Muñoz MC, Laulier C, Gunn A, Cheng A, Robbiani DF, Nussenzweig A, Stark JM.

J Biol Chem. 2012 Nov 23;287(48):40618-28. doi: 10.1074/jbc.M112.410951. Epub 2012 Oct 10.


Suberoylanilide hydroxamic acid as a radiosensitizer through modulation of RAD51 protein and inhibition of homology-directed repair in multiple myeloma.

Chen X, Wong P, Radany EH, Stark JM, Laulier C, Wong JY.

Mol Cancer Res. 2012 Aug;10(8):1052-64. doi: 10.1158/1541-7786.MCR-11-0587. Epub 2012 Jun 22.


The secret life of Bcl-2: apoptosis-independent inhibition of DNA repair by Bcl-2 family members.

Laulier C, Lopez BS.

Mutat Res. 2012 Oct-Dec;751(2):247-57. doi: 10.1016/j.mrrev.2012.05.002. Epub 2012 Jun 4. Review.


The relative efficiency of homology-directed repair has distinct effects on proper anaphase chromosome separation.

Laulier C, Cheng A, Stark JM.

Nucleic Acids Res. 2011 Aug;39(14):5935-44. doi: 10.1093/nar/gkr187. Epub 2011 Mar 31.


Bcl-2 inhibits nuclear homologous recombination by localizing BRCA1 to the endomembranes.

Laulier C, Barascu A, Guirouilh-Barbat J, Pennarun G, Le Chalony C, Chevalier F, Palierne G, Bertrand P, Verbavatz JM, Lopez BS.

Cancer Res. 2011 May 15;71(10):3590-602. doi: 10.1158/0008-5472.CAN-10-3119. Epub 2011 Mar 28.


Mammalian Fbh1 is important to restore normal mitotic progression following decatenation stress.

Laulier C, Cheng A, Huang N, Stark JM.

DNA Repair (Amst). 2010 Jun 4;9(6):708-17. doi: 10.1016/j.dnarep.2010.03.011. Epub 2010 Apr 24.


AKT1 inhibits homologous recombination by inducing cytoplasmic retention of BRCA1 and RAD51.

Plo I, Laulier C, Gauthier L, Lebrun F, Calvo F, Lopez BS.

Cancer Res. 2008 Nov 15;68(22):9404-12. doi: 10.1158/0008-5472.CAN-08-0861.


Bax and Bid, two proapoptotic Bcl-2 family members, inhibit homologous recombination, independently of apoptosis regulation.

Dumay A, Laulier C, Bertrand P, Saintigny Y, Lebrun F, Vayssière JL, Lopez BS.

Oncogene. 2006 May 25;25(22):3196-205.


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