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Items: 16

1.

A Markov chain for numerical chromosomal instability in clonally expanding populations.

Elizalde S, Laughney AM, Bakhoum SF.

PLoS Comput Biol. 2018 Sep 11;14(9):e1006447. doi: 10.1371/journal.pcbi.1006447. eCollection 2018 Sep.

2.

Chromosomal instability drives metastasis through a cytosolic DNA response.

Bakhoum SF, Ngo B, Laughney AM, Cavallo JA, Murphy CJ, Ly P, Shah P, Sriram RK, Watkins TBK, Taunk NK, Duran M, Pauli C, Shaw C, Chadalavada K, Rajasekhar VK, Genovese G, Venkatesan S, Birkbak NJ, McGranahan N, Lundquist M, LaPlant Q, Healey JH, Elemento O, Chung CH, Lee NY, Imielenski M, Nanjangud G, Pe'er D, Cleveland DW, Powell SN, Lammerding J, Swanton C, Cantley LC.

Nature. 2018 Jan 25;553(7689):467-472. doi: 10.1038/nature25432. Epub 2018 Jan 17.

3.

Predicting therapeutic nanomedicine efficacy using a companion magnetic resonance imaging nanoparticle.

Miller MA, Gadde S, Pfirschke C, Engblom C, Sprachman MM, Kohler RH, Yang KS, Laughney AM, Wojtkiewicz G, Kamaly N, Bhonagiri S, Pittet MJ, Farokhzad OC, Weissleder R.

Sci Transl Med. 2015 Nov 18;7(314):314ra183. doi: 10.1126/scitranslmed.aac6522.

4.

Dynamics of Tumor Heterogeneity Derived from Clonal Karyotypic Evolution.

Laughney AM, Elizalde S, Genovese G, Bakhoum SF.

Cell Rep. 2015 Aug 4;12(5):809-20. doi: 10.1016/j.celrep.2015.06.065. Epub 2015 Jul 23.

5.

Numerical chromosomal instability mediates susceptibility to radiation treatment.

Bakhoum SF, Kabeche L, Wood MD, Laucius CD, Qu D, Laughney AM, Reynolds GE, Louie RJ, Phillips J, Chan DA, Zaki BI, Murnane JP, Petritsch C, Compton DA.

Nat Commun. 2015 Jan 21;6:5990. doi: 10.1038/ncomms6990.

6.

Single-cell pharmacokinetic imaging reveals a therapeutic strategy to overcome drug resistance to the microtubule inhibitor eribulin.

Laughney AM, Kim E, Sprachman MM, Miller MA, Kohler RH, Yang KS, Orth JD, Mitchison TJ, Weissleder R.

Sci Transl Med. 2014 Nov 5;6(261):261ra152. doi: 10.1126/scitranslmed.3009318.

7.

In vivo imaging of multidrug resistance using a third generation MDR1 inhibitor.

Sprachman MM, Laughney AM, Kohler RH, Weissleder R.

Bioconjug Chem. 2014 Jun 18;25(6):1137-42. doi: 10.1021/bc500154c. Epub 2014 May 14.

8.

A photoactivatable drug-caged fluorophore conjugate allows direct quantification of intracellular drug transport.

Agasti SS, Laughney AM, Kohler RH, Weissleder R.

Chem Commun (Camb). 2013 Dec 7;49(94):11050-11052. doi: 10.1039/c3cc46089d.

9.

Spectral discrimination of breast pathologies in situ using spatial frequency domain imaging.

Laughney AM, Krishnaswamy V, Rizzo EJ, Schwab MC, Barth RJ Jr, Cuccia DJ, Tromberg BJ, Paulsen KD, Pogue BW, Wells WA.

Breast Cancer Res. 2013;15(4):R61.

10.

Direct identification of breast cancer pathologies using blind separation of label-free localized reflectance measurements.

Eguizabal A, Laughney AM, GarcĂ­a-Allende PB, Krishnaswamy V, Wells WA, Paulsen KD, Pogue BW, Lopez-Higuera JM, Conde OM.

Biomed Opt Express. 2013 Jun 12;4(7):1104-18. doi: 10.1364/BOE.4.001104. Print 2013 Jul 1.

11.

System analysis of spatial frequency domain imaging for quantitative mapping of surgically resected breast tissues.

Laughney AM, Krishnaswamy V, Rice TB, Cuccia DJ, Barth RJ, Tromberg BJ, Paulsen KD, Pogue BW, Wells WA.

J Biomed Opt. 2013 Mar;18(3):036012. doi: 10.1117/1.JBO.18.3.036012.

12.

Scanning in situ spectroscopy platform for imaging surgical breast tissue specimens.

Krishnaswamy V, Laughney AM, Wells WA, Paulsen KD, Pogue BW.

Opt Express. 2013 Jan 28;21(2):2185-94. doi: 10.1364/OE.21.002185.

13.

Scatter spectroscopic imaging distinguishes between breast pathologies in tissues relevant to surgical margin assessment.

Laughney AM, Krishnaswamy V, Rizzo EJ, Schwab MC, Barth RJ, Pogue BW, Paulsen KD, Wells WA.

Clin Cancer Res. 2012 Nov 15;18(22):6315-25. doi: 10.1158/1078-0432.CCR-12-0136. Epub 2012 Aug 20.

14.

Dark-field scanning in situ spectroscopy platform for broadband imaging of resected tissue.

Krishnaswamy V, Laughney AM, Paulsen KD, Pogue BW.

Opt Lett. 2011 May 15;36(10):1911-3. doi: 10.1364/OL.36.001911.

15.

Automated classification of breast pathology using local measures of broadband reflectance.

Laughney AM, Krishnaswamy V, Garcia-Allende PB, Conde OM, Wells WA, Paulsen KD, Pogue BW.

J Biomed Opt. 2010 Nov-Dec;15(6):066019. doi: 10.1117/1.3516594.

16.

Measurement of pressure-displacement kinetics of hemoglobin in normal breast tissue with near-infrared spectral imaging.

Jiang S, Pogue BW, Laughney AM, Kogel CA, Paulsen KD.

Appl Opt. 2009 Apr 1;48(10):D130-6.

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