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Metastatic Spine Disease: Should Patients With Short Life Expectancy Be Denied Surgical Care? An International Retrospective Cohort Study.

Dea N, Versteeg AL, Sahgal A, Verlaan JJ, Charest-Morin R, Rhines LD, Sciubba DM, Schuster JM, Weber MH, Lazary A, Fehlings MG, Clarke MJ, Arnold PM, Boriani S, Bettegowda C, Laufer I, Gokaslan ZL, Fisher CG.

Neurosurgery. 2019 Nov 6. pii: nyz472. doi: 10.1093/neuros/nyz472. [Epub ahead of print]


Long-term outcomes of high-dose single-fraction radiosurgery for chordomas of the spine and sacrum.

Jin CJ, Berry-Candelario J, Reiner AS, Laufer I, Higginson DS, Schmitt AM, Lis E, Barzilai O, Boland P, Yamada Y, Bilsky MH.

J Neurosurg Spine. 2019 Oct 18:1-10. doi: 10.3171/2019.7.SPINE19515. [Epub ahead of print]


Association of neurologic deficits with surgical outcomes and health-related quality of life after treatment for metastatic epidural spinal cord compression.

Barzilai O, Versteeg AL, Goodwin CR, Sahgal A, Rhines LD, Sciubba DM, Schuster JM, Weber MH, Lazary A, Fehlings MG, Clarke MJ, Arnold PM, Boriani S, Bettegowda C, Gokaslan ZL, Fisher CG, Laufer I; AOSpine Knowledge Forum Tumor.

Cancer. 2019 Dec 1;125(23):4224-4231. doi: 10.1002/cncr.32420. Epub 2019 Aug 13.


Treatment of dedifferentiated chordoma: a retrospective study from a large volume cancer center.

Nachwalter RN, Rothrock RJ, Katsoulakis E, Gounder MM, Boland PJ, Bilsky MH, Laufer I, Schmitt AM, Yamada Y, Higginson DS.

J Neurooncol. 2019 Sep;144(2):369-376. doi: 10.1007/s11060-019-03239-3. Epub 2019 Jul 23.


Adjacent level fracture incidence in single fraction high dose spinal radiosurgery.

Lockney DT, Hopkins B, Lockney NA, Coleman CZ, Rubin E, Lis E, Yamada Y, Schmitt A, Higginson D, Bilsky MH, Laufer I.

Ann Transl Med. 2019 May;7(10):211. doi: 10.21037/atm.2019.04.68.


Essential Concepts for the Management of Metastatic Spine Disease: What the Surgeon Should Know and Practice.

Barzilai O, Boriani S, Fisher CG, Sahgal A, Verlaan JJ, Gokaslan ZL, Lazary A, Bettegowda C, Rhines LD, Laufer I.

Global Spine J. 2019 May;9(1 Suppl):98S-107S. doi: 10.1177/2192568219830323. Epub 2019 May 8.


Image guidance in spine tumor surgery.

Kelly PD, Zuckerman SL, Yamada Y, Lis E, Bilsky MH, Laufer I, Barzilai O.

Neurosurg Rev. 2019 Jun 1. doi: 10.1007/s10143-019-01123-2. [Epub ahead of print] Review.


Outcome analysis of surgery for symptomatic spinal metastases in long-term cancer survivors.

Barzilai O, McLaughlin L, Lis E, Yamada Y, Bilsky MH, Laufer I.

J Neurosurg Spine. 2019 Apr 26:1-6. doi: 10.3171/2019.2.SPINE181306. [Epub ahead of print]


Advances in the treatment of metastatic spine tumors: the future is not what it used to be.

Laufer I, Bilsky MH.

J Neurosurg Spine. 2019 Mar 1;30(3):299-307. doi: 10.3171/2018.11.SPINE18709. Review.


Spinal Instability Neoplastic Score component validation using patient-reported outcomes.

Hussain I, Barzilai O, Reiner AS, McLaughlin L, DiStefano NM, Ogilvie S, Versteeg AL, Fisher CG, Bilsky MH, Laufer I.

J Neurosurg Spine. 2019 Jan 18:1-7. doi: 10.3171/2018.9.SPINE18147. [Epub ahead of print]


A NOMS Framework Solution.

Nasrallah H, Yamada Y, Laufer I, Bilsky MH.

Int J Radiat Oncol Biol Phys. 2019 Jan 1;103(1):17-18. doi: 10.1016/j.ijrobp.2018.09.026. Epub 2018 Dec 12. No abstract available.


Utility of Cement Augmentation via Percutaneous Fenestrated Pedicle Screws for Stabilization of Cancer-Related Spinal Instability.

Barzilai O, McLaughlin L, Lis E, Reiner AS, Bilsky MH, Laufer I.

Oper Neurosurg (Hagerstown). 2019 May 1;16(5):593-599. doi: 10.1093/ons/opy186.


Change in the cross-sectional area of the thecal sac following balloon kyphoplasty for pathological vertebral compression fractures prior to spine stereotactic radiosurgery.

Lis E, Laufer I, Barzilai O, Yamada Y, Karimi S, McLaughlin L, Krol G, Bilsky MH.

J Neurosurg Spine. 2018 Oct 19;30(1):111-118. doi: 10.3171/2018.6.SPINE18206.


Current treatment strategy for newly diagnosed chordoma of the mobile spine and sacrum: results of an international survey.

Dea N, Fisher CG, Reynolds JJ, Schwab JH, Rhines LD, Gokaslan ZL, Bettegowda C, Sahgal A, Lazáry Á, Luzzati A, Boriani S, Gasbarrini A, Laufer I, Charest-Morin R, Wei F, Teixeira W, Germscheid NM, Hornicek FJ, DeLaney TF, Shin JH; AOSpine Knowledge Forum Tumor.

J Neurosurg Spine. 2018 Oct 19;30(1):119-125. doi: 10.3171/2018.6.SPINE18362.


Survival, local control, and health-related quality of life in patients with oligometastatic and polymetastatic spinal tumors: A multicenter, international study.

Barzilai O, Versteeg AL, Sahgal A, Rhines LD, Bilsky MH, Sciubba DM, Schuster JM, Weber MH, Pal Varga P, Boriani S, Bettegowda C, Fehlings MG, Yamada Y, Clarke MJ, Arnold PM, Gokaslan ZL, Fisher CG, Laufer I, The Ao Spine Knowledge Forum Tumor.

Cancer. 2019 Mar 1;125(5):770-778. doi: 10.1002/cncr.31870. Epub 2018 Nov 29.


The Challenges of Renal Cell Carcinoma Metastatic to the Spine: A Systematic Review of Survival and Treatment.

Goodwin CR, Ahmed AK, Boone C, Abu-Bonsrah N, Xu R, Germscheid N, Fourney DR, Clarke M, Laufer I, Fisher CG, Bettegowda C, Sciubba DM.

Global Spine J. 2018 Aug;8(5):517-526. doi: 10.1177/2192568217737777. Epub 2017 Nov 20. Review.


Minimal Access Surgery for Spinal Metastases: Prospective Evaluation of a Treatment Algorithm Using Patient-Reported Outcomes.

Barzilai O, McLaughlin L, Amato MK, Reiner AS, Ogilvie SQ, Lis E, Yamada Y, Bilsky MH, Laufer I.

World Neurosurg. 2018 Dec;120:e889-e901. doi: 10.1016/j.wneu.2018.08.182. Epub 2018 Sep 4.


Brachytherapy in Spinal Tumors: A Systematic Review.

Zuckerman SL, Lim J, Yamada Y, Bilsky MH, Laufer I.

World Neurosurg. 2018 Oct;118:e235-e244. doi: 10.1016/j.wneu.2018.06.166. Epub 2018 Jun 30. Review.


Hybrid Therapy for Metastatic Epidural Spinal Cord Compression: Technique for Separation Surgery and Spine Radiosurgery.

Barzilai O, Laufer I, Robin A, Xu R, Yamada Y, Bilsky MH.

Oper Neurosurg (Hagerstown). 2019 Mar 1;16(3):310-318. doi: 10.1093/ons/opy137. Erratum in: Oper Neurosurg (Hagerstown). 2018 Sep 1;15(3):361.


Hybrid surgery-radiosurgery therapy for metastatic epidural spinal cord compression: A prospective evaluation using patient-reported outcomes.

Barzilai O, Amato MK, McLaughlin L, Reiner AS, Ogilvie SQ, Lis E, Yamada Y, Bilsky MH, Laufer I.

Neurooncol Pract. 2018 May;5(2):104-113. doi: 10.1093/nop/npx017. Epub 2017 Jul 22. Erratum in: Neurooncol Pract. 2018 May;5(2):73.


Highlights from the First Annual Spinal Navigation, Emerging Technologies and Systems Integration Meeting.

Drazin D, Grunert P, Hartl R, Polly D, Meyer B, Catchpole K, Laufer I, Sethi R, Perry T, Simon D, Wang M, Fisher C, Scribner M, White G, Tubbs RS, Oskouian RJ, Kim T, Johnson JP.

Ann Transl Med. 2018 Mar;6(6):110. doi: 10.21037/atm.2018.03.22.


Minimally invasive versus conventional spine surgery for vertebral metastases: a systematic review of the evidence.

Pennington Z, Ahmed AK, Molina CA, Ehresman J, Laufer I, Sciubba DM.

Ann Transl Med. 2018 Mar;6(6):103. doi: 10.21037/atm.2018.01.28. Review.


Corrigenda: Hybrid surgery-radiosurgery therapy for metastatic epidural spinal cord compression: A prospective evaluation using patient-reported outcomes.

Barzilai O, Amato MK, McLaughlin L, Reiner AS, Ogilvie SQ, Lis E, Yamada Y, Bilsky MH, Laufer I.

Neurooncol Pract. 2018 May;5(2):73. doi: 10.1093/nop/npx024. Epub 2017 Sep 23.


Population description and clinical response assessment for spinal metastases: part 2 of the SPIne response assessment in Neuro-Oncology (SPINO) group report.

Laufer I, Lo SS, Chang EL, Sheehan J, Guckenberger M, Sohn MJ, Ryu S, Foote M, Muacevic A, Soltys SG, Chao S, Myrehaug S, Gerszten PC, Lis E, Maralani P, Bilsky M, Fisher C, Rhines L, Verlaan JJ, Schiff D, Fehlings MG, Ma L, Chang S, Parulekar WR, Vogelbaum MA, Sahgal A.

Neuro Oncol. 2018 Aug 2;20(9):1215-1224. doi: 10.1093/neuonc/noy047.


Chordomas of the Skull Base, Mobile Spine, and Sacrum: An Epidemiologic Investigation of Presentation, Treatment, and Survival.

Zuckerman SL, Bilsky MH, Laufer I.

World Neurosurg. 2018 May;113:e618-e627. doi: 10.1016/j.wneu.2018.02.109. Epub 2018 Feb 25.


Relationship Between Kinematic and Physiological Indices During Braking Events of Different Intensities.

Musicant O, Botzer A, Laufer I, Collet C.

Hum Factors. 2018 May;60(3):415-427. doi: 10.1177/0018720817752595. Epub 2018 Feb 1.


Myositis following spine radiosurgery for metastatic disease: a case series.

Lockney DT, Jia AY, Lis E, Lockney NA, Liu C, Hopkins B, Higginson DS, Yamada Y, Laufer I, Bilsky M, Schmitt AM.

J Neurosurg Spine. 2018 Apr;28(4):416-421. doi: 10.3171/2017.8.SPINE17162. Epub 2018 Jan 26.


Metastases of spinal myxopapillary ependymoma: unique characteristics and clinical management.

Kraetzig T, McLaughlin L, Bilsky MH, Laufer I.

J Neurosurg Spine. 2018 Feb;28(2):201-208. doi: 10.3171/2017.5.SPINE161164. Epub 2017 Dec 8.


Predictors of quality of life improvement after surgery for metastatic tumors of the spine: prospective cohort study.

Barzilai O, McLaughlin L, Amato MK, Reiner AS, Ogilvie SQ, Lis E, Yamada Y, Bilsky MH, Laufer I.

Spine J. 2018 Jul;18(7):1109-1115. doi: 10.1016/j.spinee.2017.10.070. Epub 2017 Nov 6.


Safety and utility of kyphoplasty prior to spine stereotactic radiosurgery for metastatic tumors: a clinical and dosimetric analysis.

Barzilai O, DiStefano N, Lis E, Yamada Y, Lovelock DM, Fontanella AN, Bilsky MH, Laufer I.

J Neurosurg Spine. 2018 Jan;28(1):72-78. doi: 10.3171/2017.5.SPINE1746. Epub 2017 Nov 3.


Systematic Review of the Outcomes of Surgical Treatment of Prostate Metastases to the Spine.

Clarke MJ, Molina CA, Fourney DR, Fisher CG, Gokaslan ZL, Schmidt MH, Rhines LD, Fehlings MG, Laufer I, Patel SR, Rampersaud YR, Reynolds J, Chou D, Bettegowda C, Mendel E, Weber MH, Sciubba DM.

Global Spine J. 2017 Aug;7(5):460-468. doi: 10.1177/2192568217710911. Epub 2017 Jun 1. Review.


Modern approaches to the management of metastatic epidural spinal cord compression.

Husain ZA, Sahgal A, Chang EL, Maralani PJ, Kubicky CD, Redmond KJ, Fisher C, Laufer I, Lo SS.

CNS Oncol. 2017 Jul 18. doi: 10.2217/cns-2016-0044. [Epub ahead of print]


Predictors of complications and readmission following spinal stereotactic radiosurgery.

Lubelski D, Tanenbaum JE, Purvis TE, Bomberger TT, Goodwin CR, Laufer I, Sciubba DM.

CNS Oncol. 2017 Jul 18. doi: 10.2217/cns-2016-0048. [Epub ahead of print]


Patient-reported outcomes after surgical stabilization of spinal tumors: symptom-based validation of the Spinal Instability Neoplastic Score (SINS) and surgery.

Hussain I, Barzilai O, Reiner AS, DiStefano N, McLaughlin L, Ogilvie S, Bilsky M, Laufer I.

Spine J. 2018 Feb;18(2):261-267. doi: 10.1016/j.spinee.2017.07.008. Epub 2017 Jul 13.


Integrating Evidence-Based Medicine for Treatment of Spinal Metastases Into a Decision Framework: Neurologic, Oncologic, Mechanicals Stability, and Systemic Disease.

Barzilai O, Laufer I, Yamada Y, Higginson DS, Schmitt AM, Lis E, Bilsky MH.

J Clin Oncol. 2017 Jul 20;35(21):2419-2427. doi: 10.1200/JCO.2017.72.7362. Epub 2017 Jun 22. Review.


Stereotactic Body Radiotherapy in the Treatment of Spinal Metastases.

Katsoulakis E, Kumar K, Laufer I, Yamada Y.

Semin Radiat Oncol. 2017 Jul;27(3):209-217. doi: 10.1016/j.semradonc.2017.03.004. Epub 2017 Mar 16. Review.


Incidence and risk factors for preoperative deep venous thrombosis in 314 consecutive patients undergoing surgery for spinal metastasis.

Zacharia BE, Kahn S, Bander ED, Cederquist GY, Cope WP, McLaughlin L, Hijazi A, Reiner AS, Laufer I, Bilsky M.

J Neurosurg Spine. 2017 Aug;27(2):189-197. doi: 10.3171/2017.2.SPINE16861. Epub 2017 Jun 2.


Surgical Decompression of High-Grade Spinal Cord Compression from Hormone Refractory Metastatic Prostate Cancer.

Chohan MO, Kahn S, Cederquist G, Reiner AS, Schwab J, Laufer I, Bilsky M.

Neurosurgery. 2018 May 1;82(5):670-677. doi: 10.1093/neuros/nyx292.


The role of revision surgery and adjuvant therapy following subtotal resection of osteosarcoma of the spine: a systematic review with meta-analysis.

Shankar GM, Clarke MJ, Ailon T, Rhines LD, Patel SR, Sahgal A, Laufer I, Chou D, Bilsky MH, Sciubba DM, Fehlings MG, Fisher CG, Gokaslan ZL, Shin JH.

J Neurosurg Spine. 2017 Jul;27(1):97-104. doi: 10.3171/2016.12.SPINE16995. Epub 2017 Apr 28. Review.


Metastatic Spinal Cord Compression and Steroid Treatment: A Systematic Review.

Kumar A, Weber MH, Gokaslan Z, Wolinsky JP, Schmidt M, Rhines L, Fehlings MG, Laufer I, Sciubba DM, Clarke MJ, Sundaresan N, Verlaan JJ, Sahgal A, Chou D, Fisher CG.

Clin Spine Surg. 2017 May;30(4):156-163. doi: 10.1097/BSD.0000000000000528. Review.


Review of stereotactic radiosurgery for intradural spine tumors.

Purvis TE, Goodwin CR, Lubelski D, Laufer I, Sciubba DM.

CNS Oncol. 2017 Apr;6(2):131-138. doi: 10.2217/cns-2016-0039. Review.


Stabilization of Tumor-Associated Craniovertebral Junction Instability: Indications, Operative Variables, and Outcomes.

Zuckerman SL, Kreines F, Powers A, Iorgulescu JB, Elder JB, Bilsky MH, Laufer I.

Neurosurgery. 2017 Aug 1;81(2):251-258. doi: 10.1093/neuros/nyx070.


The SORG nomogram accurately predicts 3- and 12-months survival for operable spine metastatic disease: External validation.

Paulino Pereira NR, Mclaughlin L, Janssen SJ, van Dijk CN, Bramer JAM, Laufer I, Bilsky MH, Schwab JH.

J Surg Oncol. 2017 Jun;115(8):1019-1027. doi: 10.1002/jso.24620. Epub 2017 Mar 27.


Peripheral nervous system injury after high-dose single-fraction image-guided stereotactic radiosurgery for spine tumors.

Stubblefield MD, Ibanez K, Riedel ER, Barzilai O, Laufer I, Lis E, Yamada Y, Bilsky MH.

Neurosurg Focus. 2017 Mar;42(3):E12. doi: 10.3171/2016.11.FOCUS16348.


The impact of histology and delivered dose on local control of spinal metastases treated with stereotactic radiosurgery.

Yamada Y, Katsoulakis E, Laufer I, Lovelock M, Barzilai O, McLaughlin LA, Zhang Z, Schmitt AM, Higginson DS, Lis E, Zelefsky MJ, Mechalakos J, Bilsky MH.

Neurosurg Focus. 2017 Jan;42(1):E6. doi: 10.3171/2016.9.FOCUS16369.


Pathological characteristics of spine metastases treated with high-dose single-fraction stereotactic radiosurgery.

Katsoulakis E, Laufer I, Bilsky M, Agaram NP, Lovelock M, Yamada Y.

Neurosurg Focus. 2017 Jan;42(1):E7. doi: 10.3171/2016.10.FOCUS16368.


Frequency of symptomatic vertebral body compression fractures requiring intervention following single-fraction stereotactic radiosurgery for spinal metastases.

Virk MS, Han JE, Reiner AS, McLaughlin LA, Sciubba DM, Lis E, Yamada Y, Bilsky M, Laufer I.

Neurosurg Focus. 2017 Jan;42(1):E8. doi: 10.3171/2016.10.FOCUS16359.


Spinal stereotactic body radiotherapy following intralesional curettage with separation surgery for initial or salvage chordoma treatment.

Lockney DT, Shub T, Hopkins B, Lockney NA, Moussazadeh N, Lis E, Yamada Y, Schmitt AM, Higginson DS, Laufer I, Bilsky M.

Neurosurg Focus. 2017 Jan;42(1):E4. doi: 10.3171/2016.9.FOCUS16373.


When Less Is More: The indications for MIS Techniques and Separation Surgery in Metastatic Spine Disease.

Zuckerman SL, Laufer I, Sahgal A, Yamada YJ, Schmidt MH, Chou D, Shin JH, Kumar N, Sciubba DM.

Spine (Phila Pa 1976). 2016 Oct 15;41 Suppl 20:S246-S253. Review.

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