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Items: 1 to 50 of 142

1.

IgG Charge: Practical and Biological Implications.

Yang D, Kroe-Barrett R, Singh S, Laue T.

Antibodies (Basel). 2019 Mar 14;8(1). pii: E24. doi: 10.3390/antib8010024.

2.

Immune Status in Children Before Liver Transplantation-A Cross-Sectional Analysis Within the ChilsSFree Multicentre Cohort Study.

Möhring T, Karch A, Falk CS, Laue T, D'Antiga L, Debray D, Hierro L, Kelly D, McLin V, McKiernan P, Pawlowska J, Czubkowski P, Mikolajczyk RT, Baumann U, Goldschmidt I.

Front Immunol. 2019 Jan 25;10:52. doi: 10.3389/fimmu.2019.00052. eCollection 2019.

3.

Identification of a 57S translation complex containing closed-loop factors and the 60S ribosome subunit.

Denis CL, Laue TM, Wang X.

Sci Rep. 2018 Jul 31;8(1):11468. doi: 10.1038/s41598-018-29832-6.

4.

Weak IgG self- and hetero-association characterized by fluorescence analytical ultracentrifugation.

Yang D, Correia JJ, Stafford Iii WF, Roberts CJ, Singh S, Hayes D, Kroe-Barrett R, Nixon A, Laue TM.

Protein Sci. 2018 Jul;27(7):1334-1348. doi: 10.1002/pro.3422.

5.

Defining the protein complexome of translation termination factor eRF1: Identification of four novel eRF1-containing complexes that range from 20S to 57S in size.

Denis CL, Richardson R, Park S, Zhang C, Xi W, Laue TM, Wang X.

Proteins. 2018 Feb;86(2):177-191. doi: 10.1002/prot.25422. Epub 2017 Nov 27.

6.

IgG cooperativity - Is there allostery? Implications for antibody functions and therapeutic antibody development.

Yang D, Kroe-Barrett R, Singh S, Roberts CJ, Laue TM.

MAbs. 2017 Nov/Dec;9(8):1231-1252. doi: 10.1080/19420862.2017.1367074. Epub 2017 Aug 16. Review.

7.

Sedimentation Velocity Analysis with Fluorescence Detection of Mutant Huntingtin Exon 1 Aggregation in Drosophila melanogaster and Caenorhabditis elegans.

Kim SA, D'Acunto VF, Kokona B, Hofmann J, Cunningham NR, Bistline EM, Garcia FJ, Akhtar NM, Hoffman SH, Doshi SH, Ulrich KM, Jones NM, Bonini NM, Roberts CM, Link CD, Laue TM, Fairman R.

Biochemistry. 2017 Sep 5;56(35):4676-4688. doi: 10.1021/acs.biochem.7b00518. Epub 2017 Aug 24.

8.

Charge matters.

Laue T.

Biophys Rev. 2016 Dec;8(4):287-289. doi: 10.1007/s12551-016-0229-3. Epub 2016 Oct 20. Review. No abstract available.

9.

Using X-Ray Crystallography to Simplify and Accelerate Biologics Drug Development.

Brader ML, Baker EN, Dunn MF, Laue TM, Carpenter JF.

J Pharm Sci. 2017 Feb;106(2):477-494. doi: 10.1016/j.xphs.2016.10.017. Epub 2016 Nov 23. Review.

PMID:
27889071
10.

Protein charge determination and implications for interactions in cell extracts.

Kyne C, Jordon K, Filoti DI, Laue TM, Crowley PB.

Protein Sci. 2017 Feb;26(2):258-267. doi: 10.1002/pro.3077. Epub 2016 Dec 1.

11.

Multiple discrete soluble aggregates influence polyglutamine toxicity in a Huntington's disease model system.

Xi W, Wang X, Laue TM, Denis CL.

Sci Rep. 2016 Oct 10;6:34916. doi: 10.1038/srep34916.

12.

The Charge Properties of Phospholipid Nanodiscs.

Her C, Filoti DI, McLean MA, Sligar SG, Alexander Ross JB, Steele H, Laue TM.

Biophys J. 2016 Sep 6;111(5):989-98. doi: 10.1016/j.bpj.2016.06.041.

13.

Stoichiometry and Change of the mRNA Closed-Loop Factors as Translating Ribosomes Transit from Initiation to Elongation.

Wang X, Xi W, Toomey S, Chiang YC, Hasek J, Laue TM, Denis CL.

PLoS One. 2016 Mar 8;11(3):e0150616. doi: 10.1371/journal.pone.0150616. eCollection 2016.

14.

Studying polyglutamine aggregation in Caenorhabditis elegans using an analytical ultracentrifuge equipped with fluorescence detection.

Kokona B, May CA, Cunningham NR, Richmond L, Jay Garcia F, Durante JC, Ulrich KM, Roberts CM, Link CD, Stafford WF, Laue TM, Fairman R.

Protein Sci. 2016 Mar;25(3):605-17. doi: 10.1002/pro.2854. Epub 2015 Dec 21.

15.

Influence of Phosphatidylcholine and Calcium on Self-Association and Bile Salt Mixed Micellar Binding of the Natural Bile Pigment, Bilirubin Ditaurate.

Neubrand MW, Carey MC, Laue TM.

Biochemistry. 2015 Nov 17;54(45):6783-95. doi: 10.1021/acs.biochem.5b00874. Epub 2015 Nov 5.

PMID:
26506107
16.

Protein Assembly in Serum and the Differences from Assembly in Buffer.

Hill JJ, Laue TM.

Methods Enzymol. 2015;562:501-27. doi: 10.1016/bs.mie.2015.06.012. Epub 2015 Jul 14.

PMID:
26412665
17.

Altered NK cell function in obese healthy humans.

Laue T, Wrann CD, Hoffmann-Castendiek B, Pietsch D, Hübner L, Kielstein H.

BMC Obes. 2015 Jan 24;2:1. doi: 10.1186/s40608-014-0033-1. eCollection 2015.

18.

A multilaboratory comparison of calibration accuracy and the performance of external references in analytical ultracentrifugation.

Zhao H, Ghirlando R, Alfonso C, Arisaka F, Attali I, Bain DL, Bakhtina MM, Becker DF, Bedwell GJ, Bekdemir A, Besong TM, Birck C, Brautigam CA, Brennerman W, Byron O, Bzowska A, Chaires JB, Chaton CT, Cölfen H, Connaghan KD, Crowley KA, Curth U, Daviter T, Dean WL, Díez AI, Ebel C, Eckert DM, Eisele LE, Eisenstein E, England P, Escalante C, Fagan JA, Fairman R, Finn RM, Fischle W, de la Torre JG, Gor J, Gustafsson H, Hall D, Harding SE, Cifre JG, Herr AB, Howell EE, Isaac RS, Jao SC, Jose D, Kim SJ, Kokona B, Kornblatt JA, Kosek D, Krayukhina E, Krzizike D, Kusznir EA, Kwon H, Larson A, Laue TM, Le Roy A, Leech AP, Lilie H, Luger K, Luque-Ortega JR, Ma J, May CA, Maynard EL, Modrak-Wojcik A, Mok YF, Mücke N, Nagel-Steger L, Narlikar GJ, Noda M, Nourse A, Obsil T, Park CK, Park JK, Pawelek PD, Perdue EE, Perkins SJ, Perugini MA, Peterson CL, Peverelli MG, Piszczek G, Prag G, Prevelige PE, Raynal BD, Rezabkova L, Richter K, Ringel AE, Rosenberg R, Rowe AJ, Rufer AC, Scott DJ, Seravalli JG, Solovyova AS, Song R, Staunton D, Stoddard C, Stott K, Strauss HM, Streicher WW, Sumida JP, Swygert SG, Szczepanowski RH, Tessmer I, Toth RT 4th, Tripathy A, Uchiyama S, Uebel SF, Unzai S, Gruber AV, von Hippel PH, Wandrey C, Wang SH, Weitzel SE, Wielgus-Kutrowska B, Wolberger C, Wolff M, Wright E, Wu YS, Wubben JM, Schuck P.

PLoS One. 2015 May 21;10(5):e0126420. doi: 10.1371/journal.pone.0126420. eCollection 2015.

19.

Comparative study of analytical techniques for determining protein charge.

Filoti DI, Shire SJ, Yadav S, Laue TM.

J Pharm Sci. 2015 Jul;104(7):2123-31. doi: 10.1002/jps.24454. Epub 2015 Apr 24. Review.

PMID:
25911989
20.

Specific-ion effects on the aggregation mechanisms and protein-protein interactions for anti-streptavidin immunoglobulin gamma-1.

Barnett GV, Razinkov VI, Kerwin BA, Laue TM, Woodka AH, Butler PD, Perevozchikova T, Roberts CJ.

J Phys Chem B. 2015 May 7;119(18):5793-804. doi: 10.1021/acs.jpcb.5b01881. Epub 2015 Apr 27.

PMID:
25885209
22.

Dip-pen nanolithography-assisted protein crystallization.

Ielasi FS, Hirtz M, Sekula-Neuner S, Laue T, Fuchs H, Willaert RG.

J Am Chem Soc. 2015 Jan 14;137(1):154-7. doi: 10.1021/ja512141k. Epub 2014 Dec 29.

PMID:
25525674
23.

Only a subset of the PAB1-mRNP proteome is present in mRNA translation complexes.

Zhang C, Wang X, Park S, Chiang YC, Xi W, Laue TM, Denis CL.

Protein Sci. 2014 Aug;23(8):1036-49. doi: 10.1002/pro.2490. Epub 2014 Jun 2.

24.

Human NK cell subset functions are differentially affected by adipokines.

Huebner L, Engeli S, Wrann CD, Goudeva L, Laue T, Kielstein H.

PLoS One. 2013 Sep 30;8(9):e75703. doi: 10.1371/journal.pone.0075703. eCollection 2013.

25.

Analysis of high-affinity assembly for AMPA receptor amino-terminal domains.

Zhao H, Berger AJ, Brown PH, Kumar J, Balbo A, May CA, Casillas E Jr, Laue TM, Patterson GH, Mayer ML, Schuck P.

J Gen Physiol. 2013 Jun;141(6):747-9. No abstract available.

26.

The RRM1 domain of the poly(A)-binding protein from Saccharomyces cerevisiae is critical to control of mRNA deadenylation.

Zhang C, Lee DJ, Chiang YC, Richardson R, Park S, Wang X, Laue TM, Denis CL.

Mol Genet Genomics. 2013 Sep;288(9):401-12. doi: 10.1007/s00438-013-0759-3. Epub 2013 Jun 21.

27.

On-chip microlasers for biomolecular detection via highly localized deposition of a multifunctional phospholipid ink.

Bog U, Laue T, Grossmann T, Beck T, Wienhold T, Richter B, Hirtz M, Fuchs H, Kalt H, Mappes T.

Lab Chip. 2013 Jul 21;13(14):2701-7. doi: 10.1039/c3lc50149c.

PMID:
23649356
28.

Differential temperature-dependent multimeric assemblies of replication and repair polymerases on DNA increase processivity.

Lin HK, Chase SF, Laue TM, Jen-Jacobson L, Trakselis MA.

Biochemistry. 2012 Sep 18;51(37):7367-82. doi: 10.1021/bi300956t. Epub 2012 Sep 6.

29.

Use of the novel technique of analytical ultracentrifugation with fluorescence detection system identifies a 77S monosomal translation complex.

Wang X, Zhang C, Chiang YC, Toomey S, Power MP, Granoff ME, Richardson R, Xi W, Lee DJ, Chase S, Laue TM, Denis CL.

Protein Sci. 2012 Sep;21(9):1253-68. doi: 10.1002/pro.2110. Epub 2012 Jul 16.

30.

Characterization of conformational changes and protein-protein interactions of rod photoreceptor phosphodiesterase (PDE6).

Matte SL, Laue TM, Cote RH.

J Biol Chem. 2012 Jun 8;287(24):20111-21. doi: 10.1074/jbc.M112.354647. Epub 2012 Apr 18.

31.

Analysis of high-affinity assembly for AMPA receptor amino-terminal domains.

Zhao H, Berger AJ, Brown PH, Kumar J, Balbo A, May CA, Casillas E Jr, Laue TM, Patterson GH, Mayer ML, Schuck P.

J Gen Physiol. 2012 May;139(5):371-88. doi: 10.1085/jgp.201210770. Epub 2012 Apr 16. Erratum in: J Gen Physiol. 2013 Jun;141(6):747-9.

32.

Detection of high-molecular-weight amyloid serum protein complexes using biological on-line tracer sedimentation.

Kingsbury JS, Laue TM, Chase SF, Connors LH.

Anal Biochem. 2012 Jun 15;425(2):151-6. doi: 10.1016/j.ab.2012.03.016. Epub 2012 Mar 27.

33.

Proximity energies: a framework for understanding concentrated solutions.

Laue T.

J Mol Recognit. 2012 Mar;25(3):165-73. doi: 10.1002/jmr.2179. Review.

PMID:
22407980
34.

Effect of PEGylation on protein hydrodynamics.

Gokarn YR, McLean M, Laue TM.

Mol Pharm. 2012 Apr 2;9(4):762-73. doi: 10.1021/mp200470c. Epub 2012 Mar 22.

PMID:
22353017
35.

The influence of charge distribution on self-association and viscosity behavior of monoclonal antibody solutions.

Yadav S, Laue TM, Kalonia DS, Singh SN, Shire SJ.

Mol Pharm. 2012 Apr 2;9(4):791-802. doi: 10.1021/mp200566k. Epub 2012 Mar 19.

PMID:
22352470
36.

The role of immunoglobulin A in prolonged and relapsing hepatitis A virus infections.

Dotzauer A, Heitmann A, Laue T, Kraemer L, Schwabe K, Paulmann D, Flehmig B, Vallbracht A.

J Gen Virol. 2012 Apr;93(Pt 4):754-60. doi: 10.1099/vir.0.038406-0. Epub 2011 Dec 14.

PMID:
22170633
37.

Short-term and long-term leptin exposure differentially affect human natural killer cell immune functions.

Wrann CD, Laue T, Hübner L, Kuhlmann S, Jacobs R, Goudeva L, Nave H.

Am J Physiol Endocrinol Metab. 2012 Jan 1;302(1):E108-16. doi: 10.1152/ajpendo.00057.2011. Epub 2011 Sep 27.

38.

Multiple conformations of the cytidine repressor DNA-binding domain coalesce to one upon recognition of a specific DNA surface.

Moody CL, Tretyachenko-Ladokhina V, Laue TM, Senear DF, Cocco MJ.

Biochemistry. 2011 Aug 9;50(31):6622-32. doi: 10.1021/bi200205v. Epub 2011 Jul 18.

PMID:
21688840
39.

A postreductionist framework for protein biochemistry.

Laue T, Demeler B.

Nat Chem Biol. 2011 Jun;7(6):331-4. doi: 10.1038/nchembio.575. No abstract available.

PMID:
21587250
40.

Effective charge measurements reveal selective and preferential accumulation of anions, but not cations, at the protein surface in dilute salt solutions.

Gokarn YR, Fesinmeyer RM, Saluja A, Razinkov V, Chase SF, Laue TM, Brems DN.

Protein Sci. 2011 Mar;20(3):580-7. doi: 10.1002/pro.591.

41.

Fluorescence-detected sedimentation in dilute and highly concentrated solutions.

Kingsbury JS, Laue TM.

Methods Enzymol. 2011;492:283-304. doi: 10.1016/B978-0-12-381268-1.00021-5.

PMID:
21333796
42.

Nonnative aggregation of an IgG1 antibody in acidic conditions: part 1. Unfolding, colloidal interactions, and formation of high-molecular-weight aggregates.

Brummitt RK, Nesta DP, Chang L, Chase SF, Laue TM, Roberts CJ.

J Pharm Sci. 2011 Jun;100(6):2087-103. doi: 10.1002/jps.22448. Epub 2011 Jan 6.

PMID:
21213308
43.

Substrate-independent dip-pen nanolithography based on reactive coatings.

Chen HY, Hirtz M, Deng X, Laue T, Fuchs H, Lahann J.

J Am Chem Soc. 2010 Dec 29;132(51):18023-5. doi: 10.1021/ja108679m. Epub 2010 Dec 7.

PMID:
21138264
44.

Singleplex real-time RT-PCR for detection of influenza A virus and simultaneous differentiation of A/H1N1v and evaluation of the RealStar influenza kit.

Panning M, Baumgarte S, Laue T, Bierbaum S, Raith S, Drexler JF, Helmer A, Falcone-Kapper V, Kochs G, Campe H, Huzly D, Eis-Hübinger AM, Drosten C.

J Clin Virol. 2011 Feb;50(2):171-4. doi: 10.1016/j.jcv.2010.10.010. Epub 2010 Nov 13.

PMID:
21075679
45.

The sedimentation properties of ferritins. New insights and analysis of methods of nanoparticle preparation.

May CA, Grady JK, Laue TM, Poli M, Arosio P, Chasteen ND.

Biochim Biophys Acta. 2010 Aug;1800(8):858-70. doi: 10.1016/j.bbagen.2010.03.012. Epub 2010 Mar 20. Review.

46.

Lipid multilayer gratings.

Lenhert S, Brinkmann F, Laue T, Walheim S, Vannahme C, Klinkhammer S, Xu M, Sekula S, Mappes T, Schimmel T, Fuchs H.

Nat Nanotechnol. 2010 Apr;5(4):275-9. doi: 10.1038/nnano.2010.17. Epub 2010 Feb 28.

PMID:
20190751
47.

Determination of size, molecular weight, and presence of subunits.

Rhodes DG, Bossio RE, Laue TM.

Methods Enzymol. 2009;463:691-723. doi: 10.1016/S0076-6879(09)63039-1. Review.

PMID:
19892199
48.

Determination of protein purity.

Rhodes DG, Laue TM.

Methods Enzymol. 2009;463:677-89. doi: 10.1016/S0076-6879(09)63038-X. Review.

PMID:
19892198
49.

The Open AUC Project.

Cölfen H, Laue TM, Wohlleben W, Schilling K, Karabudak E, Langhorst BW, Brookes E, Dubbs B, Zollars D, Rocco M, Demeler B.

Eur Biophys J. 2010 Feb;39(3):347-59. doi: 10.1007/s00249-009-0438-9. Epub 2009 Mar 19.

50.

NUTS and BOLTS: applications of fluorescence-detected sedimentation.

Kroe RR, Laue TM.

Anal Biochem. 2009 Jul 1;390(1):1-13. doi: 10.1016/j.ab.2008.11.033. Epub 2008 Dec 6.

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