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Items: 1 to 50 of 83

1.

Citrullination of HP1γ chromodomain affects association with chromatin.

Wiese M, Bannister AJ, Basu S, Boucher W, Wohlfahrt K, Christophorou MA, Nielsen ML, Klenerman D, Laue ED, Kouzarides T.

Epigenetics Chromatin. 2019 Apr 2;12(1):21. doi: 10.1186/s13072-019-0265-x.

2.

FRET-enhanced photostability allows improved single-molecule tracking of proteins and protein complexes in live mammalian cells.

Basu S, Needham LM, Lando D, Taylor EJR, Wohlfahrt KJ, Shah D, Boucher W, Tan YL, Bates LE, Tkachenko O, Cramard J, Lagerholm BC, Eggeling C, Hendrich B, Klenerman D, Lee SF, Laue ED.

Nat Commun. 2018 Jun 28;9(1):2520. doi: 10.1038/s41467-018-04486-0.

3.

Combining fluorescence imaging with Hi-C to study 3D genome architecture of the same single cell.

Lando D, Basu S, Stevens TJ, Riddell A, Wohlfahrt KJ, Cao Y, Boucher W, Leeb M, Atkinson LP, Lee SF, Hendrich B, Klenerman D, Laue ED.

Nat Protoc. 2018 May;13(5):1034-1061. doi: 10.1038/nprot.2018.017. Epub 2018 Apr 19.

PMID:
29674753
4.
5.

Architecture of TAF11/TAF13/TBP complex suggests novel regulation properties of general transcription factor TFIID.

Gupta K, Watson AA, Baptista T, Scheer E, Chambers AL, Koehler C, Zou J, Obong-Ebong I, Kandiah E, Temblador A, Round A, Forest E, Man P, Bieniossek C, Laue ED, Lemke EA, Rappsilber J, Robinson CV, Devys D, Tora L, Berger I.

Elife. 2017 Nov 7;6. pii: e30395. doi: 10.7554/eLife.30395.

6.

Are There Knots in Chromosomes?

Siebert JT, Kivel AN, Atkinson LP, Stevens TJ, Laue ED, Virnau P.

Polymers (Basel). 2017 Aug 2;9(8). pii: E317. doi: 10.3390/polym9080317.

7.

Three-Dimensional Super-Resolution in Eukaryotic Cells Using the Double-Helix Point Spread Function.

Carr AR, Ponjavic A, Basu S, McColl J, Santos AM, Davis S, Laue ED, Klenerman D, Lee SF.

Biophys J. 2017 Apr 11;112(7):1444-1454. doi: 10.1016/j.bpj.2017.02.023.

8.

3D structures of individual mammalian genomes studied by single-cell Hi-C.

Stevens TJ, Lando D, Basu S, Atkinson LP, Cao Y, Lee SF, Leeb M, Wohlfahrt KJ, Boucher W, O'Shaughnessy-Kirwan A, Cramard J, Faure AJ, Ralser M, Blanco E, Morey L, Sansó M, Palayret MGS, Lehner B, Di Croce L, Wutz A, Hendrich B, Klenerman D, Laue ED.

Nature. 2017 Apr 6;544(7648):59-64. doi: 10.1038/nature21429. Epub 2017 Mar 13.

9.

A microfluidic platform for trapping, releasing and super-resolution imaging of single cells.

Zhou Y, Basu S, Wohlfahrt KJ, Lee SF, Klenerman D, Laue ED, Seshia AA.

Sens Actuators B Chem. 2016 Sep;232:680-691.

10.

Dynamic monitoring of single cell lysis in an impedance-based microfluidic device.

Zhou Y, Basu S, Laue ED, Seshia AA.

Biomed Microdevices. 2016 Aug;18(4):56. doi: 10.1007/s10544-016-0081-z.

11.

Studying the Dynamics of Chromatin-Binding Proteins in Mammalian Cells Using Single-Molecule Localisation Microscopy.

Basu S, Tan YL, Taylor EJ, Laue ED, Lee SF.

Methods Mol Biol. 2016;1431:235-63. doi: 10.1007/978-1-4939-3631-1_17.

PMID:
27283313
12.

The Nucleosome Remodeling and Deacetylase Complex NuRD Is Built from Preformed Catalytically Active Sub-modules.

Zhang W, Aubert A, Gomez de Segura JM, Karuppasamy M, Basu S, Murthy AS, Diamante A, Drury TA, Balmer J, Cramard J, Watson AA, Lando D, Lee SF, Palayret M, Kloet SL, Smits AH, Deery MJ, Vermeulen M, Hendrich B, Klenerman D, Schaffitzel C, Berger I, Laue ED.

J Mol Biol. 2016 Jul 17;428(14):2931-42. doi: 10.1016/j.jmb.2016.04.025. Epub 2016 Apr 23.

13.

The pentameric nucleoplasmin fold is present in Drosophila FKBP39 and a large number of chromatin-related proteins.

Edlich-Muth C, Artero JB, Callow P, Przewloka MR, Watson AA, Zhang W, Glover DM, Debski J, Dadlez M, Round AR, Forsyth VT, Laue ED.

J Mol Biol. 2015 May 22;427(10):1949-63. doi: 10.1016/j.jmb.2015.03.010. Epub 2015 Mar 24.

14.

Structure calculation, refinement and validation using CcpNmr Analysis.

Skinner SP, Goult BT, Fogh RH, Boucher W, Stevens TJ, Laue ED, Vuister GW.

Acta Crystallogr D Biol Crystallogr. 2015 Jan 1;71(Pt 1):154-61. doi: 10.1107/S1399004714026662. Epub 2015 Jan 1.

15.

Insight into the architecture of the NuRD complex: structure of the RbAp48-MTA1 subcomplex.

Alqarni SS, Murthy A, Zhang W, Przewloka MR, Silva AP, Watson AA, Lejon S, Pei XY, Smits AH, Kloet SL, Wang H, Shepherd NE, Stokes PH, Blobel GA, Vermeulen M, Glover DM, Mackay JP, Laue ED.

J Biol Chem. 2014 Aug 8;289(32):21844-55. doi: 10.1074/jbc.M114.558940. Epub 2014 Jun 11.

16.

Single-cell Hi-C reveals cell-to-cell variability in chromosome structure.

Nagano T, Lubling Y, Stevens TJ, Schoenfelder S, Yaffe E, Dean W, Laue ED, Tanay A, Fraser P.

Nature. 2013 Oct 3;502(7469):59-64. doi: 10.1038/nature12593. Epub 2013 Sep 25.

17.

High-resolution heteronuclear multidimensional NMR of proteins in living insect cells using a baculovirus protein expression system.

Hamatsu J, O'Donovan D, Tanaka T, Shirai T, Hourai Y, Mikawa T, Ikeya T, Mishima M, Boucher W, Smith BO, Laue ED, Shirakawa M, Ito Y.

J Am Chem Soc. 2013 Feb 6;135(5):1688-91. doi: 10.1021/ja310928u. Epub 2013 Jan 27.

PMID:
23327446
18.

Structural plasticity of histones H3-H4 facilitates their allosteric exchange between RbAp48 and ASF1.

Zhang W, Tyl M, Ward R, Sobott F, Maman J, Murthy AS, Watson AA, Fedorov O, Bowman A, Owen-Hughes T, El Mkami H, Murzina NV, Norman DG, Laue ED.

Nat Struct Mol Biol. 2013 Jan;20(1):29-35. doi: 10.1038/nsmb.2446. Epub 2012 Nov 25.

19.

In support of the BMRB.

Markley JL, Akutsu H, Asakura T, Baldus M, Boelens R, Bonvin A, Kaptein R, Bax A, Bezsonova I, Gryk MR, Hoch JC, Korzhnev DM, Maciejewski MW, Case D, Chazin WJ, Cross TA, Dames S, Kessler H, Lange O, Madl T, Reif B, Sattler M, Eliezer D, Fersht A, Forman-Kay J, Kay LE, Fraser J, Gross J, Kortemme T, Sali A, Fujiwara T, Gardner K, Luo X, Rizo-Rey J, Rosen M, Gil RR, Ho C, Rule G, Gronenborn AM, Ishima R, Klein-Seetharaman J, Tang P, van der Wel P, Xu Y, Grzesiek S, Hiller S, Seelig J, Laue ED, Mott H, Nietlispach D, Barsukov I, Lian LY, Middleton D, Blumenschein T, Moore G, Campbell I, Schnell J, Vakonakis IJ, Watts A, Conte MR, Mason J, Pfuhl M, Sanderson MR, Craven J, Williamson M, Dominguez C, Roberts G, Günther U, Overduin M, Werner J, Williamson P, Blindauer C, Crump M, Driscoll P, Frenkiel T, Golovanov A, Matthews S, Parkinson J, Uhrin D, Williams M, Neuhaus D, Oschkinat H, Ramos A, Shaw DE, Steinbeck C, Vendruscolo M, Vuister GW, Walters KJ, Weinstein H, Wüthrich K, Yokoyama S.

Nat Struct Mol Biol. 2012 Sep;19(9):854-60. doi: 10.1038/nsmb.2371. No abstract available.

PMID:
22955930
20.

Quantitative single-molecule microscopy reveals that CENP-A(Cnp1) deposition occurs during G2 in fission yeast.

Lando D, Endesfelder U, Berger H, Subramanian L, Dunne PD, McColl J, Klenerman D, Carr AM, Sauer M, Allshire RC, Heilemann M, Laue ED.

Open Biol. 2012 Jul;2(7):120078. doi: 10.1098/rsob.120078.

21.

The PHD and chromo domains regulate the ATPase activity of the human chromatin remodeler CHD4.

Watson AA, Mahajan P, Mertens HD, Deery MJ, Zhang W, Pham P, Du X, Bartke T, Zhang W, Edlich C, Berridge G, Chen Y, Burgess-Brown NA, Kouzarides T, Wiechens N, Owen-Hughes T, Svergun DI, Gileadi O, Laue ED.

J Mol Biol. 2012 Sep 7;422(1):3-17. doi: 10.1016/j.jmb.2012.04.031. Epub 2012 May 7.

22.

The S. pombe histone H2A dioxygenase Ofd2 regulates gene expression during hypoxia.

Lando D, Balmer J, Laue ED, Kouzarides T.

PLoS One. 2012;7(1):e29765. doi: 10.1371/journal.pone.0029765. Epub 2012 Jan 3.

23.

A software framework for analysing solid-state MAS NMR data.

Stevens TJ, Fogh RH, Boucher W, Higman VA, Eisenmenger F, Bardiaux B, van Rossum BJ, Oschkinat H, Laue ED.

J Biomol NMR. 2011 Dec;51(4):437-47. doi: 10.1007/s10858-011-9569-2. Epub 2011 Sep 28.

24.

Nessun Dorma, a novel centralspindlin partner, is required for cytokinesis in Drosophila spermatocytes.

Montembault E, Zhang W, Przewloka MR, Archambault V, Sevin EW, Laue ED, Glover DM, D'Avino PP.

J Cell Biol. 2010 Dec 27;191(7):1351-65. doi: 10.1083/jcb.201007060.

25.

Insights into association of the NuRD complex with FOG-1 from the crystal structure of an RbAp48·FOG-1 complex.

Lejon S, Thong SY, Murthy A, AlQarni S, Murzina NV, Blobel GA, Laue ED, Mackay JP.

J Biol Chem. 2011 Jan 14;286(2):1196-203. doi: 10.1074/jbc.M110.195842. Epub 2010 Nov 2.

26.

MEMOPS: data modelling and automatic code generation.

Fogh RH, Boucher W, Ionides JM, Vranken WF, Stevens TJ, Laue ED.

J Integr Bioinform. 2010 Mar 25;7(3). doi: 10.2390/biecoll-jib-2010-123.

PMID:
20375445
27.

Isolation of protein complexes involved in mitosis and cytokinesis from Drosophila cultured cells.

D'Avino PP, Archambault V, Przewloka MR, Zhang W, Laue ED, Glover DM.

Methods Mol Biol. 2009;545:99-112. doi: 10.1007/978-1-60327-993-2_6.

PMID:
19475384
28.

Structural basis for the recognition of histone H4 by the histone-chaperone RbAp46.

Murzina NV, Pei XY, Zhang W, Sparkes M, Vicente-Garcia J, Pratap JV, McLaughlin SH, Ben-Shahar TR, Verreault A, Luisi BF, Laue ED.

Structure. 2008 Jul;16(7):1077-85. doi: 10.1016/j.str.2008.05.006. Epub 2008 Jun 19.

29.

Interaction between Anillin and RacGAP50C connects the actomyosin contractile ring with spindle microtubules at the cell division site.

D'Avino PP, Takeda T, Capalbo L, Zhang W, Lilley KS, Laue ED, Glover DM.

J Cell Sci. 2008 Apr 15;121(Pt 8):1151-8. doi: 10.1242/jcs.026716. Epub 2008 Mar 18.

30.

Folding mechanism of an ankyrin repeat protein: scaffold and active site formation of human CDK inhibitor p19(INK4d).

Löw C, Weininger U, Zeeb M, Zhang W, Laue ED, Schmid FX, Balbach J.

J Mol Biol. 2007 Oct 12;373(1):219-31. Epub 2007 Aug 10.

PMID:
17804013
31.

Conformational dynamics of the molecular chaperone Hsp90 in complexes with a co-chaperone and anticancer drugs.

Phillips JJ, Yao ZP, Zhang W, McLaughlin S, Laue ED, Robinson CV, Jackson SE.

J Mol Biol. 2007 Oct 5;372(5):1189-203. Epub 2007 Apr 27.

PMID:
17764690
32.

Molecular analysis of core kinetochore composition and assembly in Drosophila melanogaster.

Przewloka MR, Zhang W, Costa P, Archambault V, D'Avino PP, Lilley KS, Laue ED, McAinsh AD, Glover DM.

PLoS One. 2007 May 30;2(5):e478.

33.

Genome-wide studies of histone demethylation catalysed by the fission yeast homologues of mammalian LSD1.

Opel M, Lando D, Bonilla C, Trewick SC, Boukaba A, Walfridsson J, Cauwood J, Werler PJ, Carr AM, Kouzarides T, Murzina NV, Allshire RC, Ekwall K, Laue ED.

PLoS One. 2007 Apr 18;2(4):e386.

34.

Multiple protein phosphatases are required for mitosis in Drosophila.

Chen F, Archambault V, Kar A, Lio' P, D'Avino PP, Sinka R, Lilley K, Laue ED, Deak P, Capalbo L, Glover DM.

Curr Biol. 2007 Feb 20;17(4):293-303.

35.

The crystal structure of the BAR domain from human Bin1/amphiphysin II and its implications for molecular recognition.

Casal E, Federici L, Zhang W, Fernandez-Recio J, Priego EM, Miguel RN, DuHadaway JB, Prendergast GC, Luisi BF, Laue ED.

Biochemistry. 2006 Oct 31;45(43):12917-28.

36.

Investigation of biotin-streptavidin binding interactions using microcantilever sensors.

Shu W, Laue ED, Seshia AA.

Biosens Bioelectron. 2007 Apr 15;22(9-10):2003-9. Epub 2006 Oct 12.

PMID:
17045792
37.

A nomenclature and data model to describe NMR experiments.

Fogh RH, Vranken WF, Boucher W, Stevens TJ, Laue ED.

J Biomol NMR. 2006 Nov;36(3):147-55. Epub 2006 Sep 22.

PMID:
17031528
38.

The co-chaperone p23 arrests the Hsp90 ATPase cycle to trap client proteins.

McLaughlin SH, Sobott F, Yao ZP, Zhang W, Nielsen PR, Grossmann JG, Laue ED, Robinson CV, Jackson SE.

J Mol Biol. 2006 Feb 24;356(3):746-58. Epub 2005 Dec 15.

PMID:
16403413
39.

Specificity determinants on Cdc42 for binding its effector protein ACK.

Elliot-Smith AE, Mott HR, Lowe PN, Laue ED, Owen D.

Biochemistry. 2005 Sep 20;44(37):12373-83.

PMID:
16156650
40.

Structure of the chromo barrel domain from the MOF acetyltransferase.

Nielsen PR, Nietlispach D, Buscaino A, Warner RJ, Akhtar A, Murzin AG, Murzina NV, Laue ED.

J Biol Chem. 2005 Sep 16;280(37):32326-31. Epub 2005 Jun 17.

41.

The CCPN data model for NMR spectroscopy: development of a software pipeline.

Vranken WF, Boucher W, Stevens TJ, Fogh RH, Pajon A, Llinas M, Ulrich EL, Markley JL, Ionides J, Laue ED.

Proteins. 2005 Jun 1;59(4):687-96.

PMID:
15815974
42.

A framework for scientific data modeling and automated software development.

Fogh RH, Boucher W, Vranken WF, Pajon A, Stevens TJ, Bhat TN, Westbrook J, Ionides JM, Laue ED.

Bioinformatics. 2005 Apr 15;21(8):1678-84. Epub 2004 Dec 21.

PMID:
15613391
43.

Structure determination of protein complexes by NMR.

Nietlispach D, Mott HR, Stott KM, Nielsen PR, Thiru A, Laue ED.

Methods Mol Biol. 2004;278:255-88.

PMID:
15318000
44.

Biochemical and structural studies of the interaction of Cdc37 with Hsp90.

Zhang W, Hirshberg M, McLaughlin SH, Lazar GA, Grossmann JG, Nielsen PR, Sobott F, Robinson CV, Jackson SE, Laue ED.

J Mol Biol. 2004 Jul 16;340(4):891-907.

PMID:
15223329
45.

Expression, purification, and biophysical studies of chromodomain proteins.

Nielsen PR, Callaghan J, Murzin AG, Murzina NV, Laue ED.

Methods Enzymol. 2004;376:148-70. Review. No abstract available.

PMID:
14975304
46.

Structural basis of HP1/PXVXL motif peptide interactions and HP1 localisation to heterochromatin.

Thiru A, Nietlispach D, Mott HR, Okuwaki M, Lyon D, Nielsen PR, Hirshberg M, Verreault A, Murzina NV, Laue ED.

EMBO J. 2004 Feb 11;23(3):489-99. Epub 2004 Feb 5.

47.

A novel method for the biosynthesis of deuterated proteins with selective protonation at the aromatic rings of Phe, Tyr and Trp.

Rajesh S, Nietlispach D, Nakayama H, Takio K, Laue ED, Shibata T, Ito Y.

J Biomol NMR. 2003 Sep;27(1):81-6.

PMID:
12878843
48.

A novel approach for the sequential backbone assignment of larger proteins: selective intra-HNCA and DQ-HNCA.

Nietlispach D, Ito Y, Laue ED.

J Am Chem Soc. 2002 Sep 18;124(37):11199-207.

PMID:
12224968
49.

Structure of the HP1 chromodomain bound to histone H3 methylated at lysine 9.

Nielsen PR, Nietlispach D, Mott HR, Callaghan J, Bannister A, Kouzarides T, Murzin AG, Murzina NV, Laue ED.

Nature. 2002 Mar 7;416(6876):103-7. Epub 2002 Feb 20.

PMID:
11882902
50.

New approaches to study macromolecular structure and function

Brunger AT, Laue ED.

Curr Opin Struct Biol. 2000 Oct;10(5):557. No abstract available.

PMID:
11042453

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