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Items: 1 to 50 of 105

1.

Ceritinib plus nivolumab in patients with advanced ALK-rearranged non-small-cell lung cancer: results of an open-label, multicenter, phase 1B study: Ceritinib plus nivolumab in ALK-rearranged NSCLC.

Felip E, de Braud FG, Maur M, Loong HH, Shaw AT, Vansteenkiste JF, John T, Liu G, Lolkema MP, Selvaggi G, Giannone V, Cazorla P, Baum J, Balbin OA, Wang LV, Lau YY, Scott JW, Shao-Weng Tan D.

J Thorac Oncol. 2019 Oct 18. pii: S1556-0864(19)33564-6. doi: 10.1016/j.jtho.2019.10.006. [Epub ahead of print]

PMID:
31634667
2.

Dickeya undicola sp. nov., a novel species for pectinolytic isolates from surface waters in Europe and Asia.

Oulghazi S, Pédron J, Cigna J, Lau YY, Moumni M, Van Gijsegem F, Chan KG, Faure D.

Int J Syst Evol Microbiol. 2019 Aug;69(8):2440-2444. doi: 10.1099/ijsem.0.003497. Epub 2019 Jun 5.

PMID:
31166160
3.

Application of time-dependent modeling for the exposure-efficacy analysis of ceritinib in untreated ALK-rearranged advanced NSCLC patients.

Lau YY, Gu W, Ho YY, Hong Y, Zhang X, Urban P.

Cancer Chemother Pharmacol. 2019 Sep;84(3):501-511. doi: 10.1007/s00280-019-03830-5. Epub 2019 Apr 24.

PMID:
31020351
4.

[Construction and application of the core technology system of digital intelligent diagnostic and treatment for hepato-biliary-pancreatic diseases].

Fang CH, Zhang P, Lau YY, Zhong SZ.

Zhonghua Wai Ke Za Zhi. 2019 Apr 1;57(4):253-257. doi: 10.3760/cma.j.issn.0529-5815.2019.04.003. Chinese.

PMID:
30929369
5.

Efficacy and Safety of Ceritinib (450 mg/d or 600 mg/d) With Food Versus 750-mg/d Fasted in Patients With ALK Receptor Tyrosine Kinase (ALK)-Positive NSCLC: Primary Efficacy Results From the ASCEND-8 Study.

Cho BC, Obermannova R, Bearz A, McKeage M, Kim DW, Batra U, Borra G, Orlov S, Kim SW, Geater SL, Postmus PE, Laurie SA, Park K, Yang CT, Ardizzoni A, Bettini AC, de Castro G Jr, Kiertsman F, Chen Z, Lau YY, Viraswami-Appanna K, Passos VQ, Dziadziuszko R.

J Thorac Oncol. 2019 Jul;14(7):1255-1265. doi: 10.1016/j.jtho.2019.03.002. Epub 2019 Mar 7.

6.

Prenatal exposure to dioxins and subsequent neurocognitive and developmental function in Hong Kong Chinese children.

Hui LL, Lam HS, Lau EY, Nelson EA, Wong TW, Fielding R.

Hong Kong Med J. 2019 Feb;25 Suppl 3(1):35-39. No abstract available.

7.

Transfer of the waterfall source isolate Pectobacterium carotovorum M022 to Pectobacterium fontis sp. nov., a deep-branching species within the genus Pectobacterium.

Oulghazi S, Cigna J, Lau YY, Moumni M, Chan KG, Faure D.

Int J Syst Evol Microbiol. 2019 Feb;69(2):470-475. doi: 10.1099/ijsem.0.003180. Epub 2019 Jan 2.

PMID:
30601112
8.

Large right atrial myxoma presenting with heart failure.

Alamri Y, Lau YY, Lainchbury J.

ANZ J Surg. 2019 Oct;89(10):1341-1342. doi: 10.1111/ans.14720. Epub 2018 Jul 8. No abstract available.

PMID:
29984482
9.

Cloning and characterization of short-chain N-acyl homoserine lactone-producing Enterobacter asburiae strain L1 from lettuce leaves.

Lau YY, How KY, Yin WF, Chan KG.

Microbiologyopen. 2018 Dec;7(6):e00610. doi: 10.1002/mbo3.610. Epub 2018 Jul 7.

10.

Recent Advances in Molecular Diagnosis of Pseudomonasaeruginosa Infection by State-of-the-Art Genotyping Techniques.

Chen JW, Lau YY, Krishnan T, Chan KG, Chang CY.

Front Microbiol. 2018 May 28;9:1104. doi: 10.3389/fmicb.2018.01104. eCollection 2018.

11.

Mesenteric fibromatosis: a rare cause of peritonitis.

Ng EP, Kwok SY, Lok KF, Chow MP, Lau PY.

Hong Kong Med J. 2018 Feb;24(1):84-6. doi: 10.12809/hkmj166276. No abstract available.

12.

Degradation reaction of Diazo reactive black 5 dye with copper (II) sulfate catalyst in thermolysis treatment.

Lau YY, Wong YS, Ang TZ, Ong SA, Lutpi NA, Ho LN.

Environ Sci Pollut Res Int. 2018 Mar;25(7):7067-7075. doi: 10.1007/s11356-017-1069-9. Epub 2017 Dec 23.

PMID:
29275478
13.

[Ten years retrospective review of the application of digital medical technology in general surgery in China].

Fang CH, Lau YY, Zhou WP, Cai W.

Zhonghua Wai Ke Za Zhi. 2017 Dec 1;55(12):887-890. doi: 10.3760/cma.j.issn.0529-5815.2017.12.002. Chinese.

PMID:
29224260
14.

Weavable, Conductive Yarn-Based NiCo//Zn Textile Battery with High Energy Density and Rate Capability.

Huang Y, Ip WS, Lau YY, Sun J, Zeng J, Yeung NSS, Ng WS, Li H, Pei Z, Xue Q, Wang Y, Yu J, Hu H, Zhi C.

ACS Nano. 2017 Sep 26;11(9):8953-8961. doi: 10.1021/acsnano.7b03322. Epub 2017 Aug 18.

PMID:
28813141
15.

Erratum to: Changes in dural sac caliber with standing MRI improve correlation with symptoms of lumbar spinal stenosis.

Lau YYO, Lee RKL, Griffith JF, Chan CLY, Law SW, Kwok KO.

Eur Spine J. 2017 Oct;26(10):2676-2677. doi: 10.1007/s00586-017-5237-x. No abstract available.

PMID:
28776130
16.

ASCEND-8: A Randomized Phase 1 Study of Ceritinib, 450 mg or 600 mg, Taken with a Low-Fat Meal versus 750 mg in Fasted State in Patients with Anaplastic Lymphoma Kinase (ALK)-Rearranged Metastatic Non-Small Cell Lung Cancer (NSCLC).

Cho BC, Kim DW, Bearz A, Laurie SA, McKeage M, Borra G, Park K, Kim SW, Ghosn M, Ardizzoni A, Maiello E, Greystoke A, Yu R, Osborne K, Gu W, Scott JW, Passos VQ, Lau YY, Wrona A.

J Thorac Oncol. 2017 Sep;12(9):1357-1367. doi: 10.1016/j.jtho.2017.07.005. Epub 2017 Jul 17.

17.

Changes in dural sac caliber with standing MRI improve correlation with symptoms of lumbar spinal stenosis.

Lau YYO, Lee RKL, Griffith JF, Chan CLY, Law SW, Kwok KO.

Eur Spine J. 2017 Oct;26(10):2666-2675. doi: 10.1007/s00586-017-5211-7. Epub 2017 Jul 12. Erratum in: Eur Spine J. 2017 Aug 3;:.

PMID:
28702785
18.

Assessment of drug-drug interaction potential between ceritinib and proton pump inhibitors in healthy subjects and in patients with ALK-positive non-small cell lung cancer.

Lau YY, Gu W, Lin T, Viraswami-Appanna K, Cai C, Scott JW, Shi M.

Cancer Chemother Pharmacol. 2017 Jun;79(6):1119-1128. doi: 10.1007/s00280-017-3308-7. Epub 2017 Apr 19.

PMID:
28424965
19.

Population Pharmacokinetics of Ceritinib in Adult Patients With Tumors Characterized by Genetic Abnormalities in Anaplastic Lymphoma Kinase.

Hong Y, Passos VQ, Huang PH, Lau YY.

J Clin Pharmacol. 2017 May;57(5):652-662. doi: 10.1002/jcph.849. Epub 2016 Dec 6.

PMID:
27922734
20.

Predation by Red Foxes (Vulpes vulpes) at an Outdoor Piggery.

Fleming PA, Dundas SJ, Lau YY, Pluske JR.

Animals (Basel). 2016 Oct 8;6(10). pii: E60.

21.

Catalytic Asymmetric Synthesis of Morpholines. Using Mechanistic Insights To Realize the Enantioselective Synthesis of Piperazines.

Lau YY, Zhai H, Schafer LL.

J Org Chem. 2016 Oct 7;81(19):8696-8709. Epub 2016 Sep 26.

PMID:
27668321
22.

[The clinical advantage of using three dimensional visualization technology in hepatic surgery].

Lau YY, Lau XX.

Zhonghua Wai Ke Za Zhi. 2016 Sep 1;54(9):661-3. doi: 10.3760/cma.j.issn.0529-5815.2016.09.003. Chinese.

PMID:
27587207
23.

Improvement of learning domains of nursing students with the use of authentic assessment pedagogy in clinical practice.

Chong EJ, Lim JS, Liu Y, Lau YY, Wu VX.

Nurse Educ Pract. 2016 Sep;20:125-30. doi: 10.1016/j.nepr.2016.08.002. Epub 2016 Aug 8.

PMID:
27583814
24.

Therapeutic inertia in the management of hyperlipidaemia in type 2 diabetic patients: a cross-sectional study in the primary care setting.

Man FY, Chen CX, Lau YY, Chan K.

Hong Kong Med J. 2016 Aug;22(4):356-64. doi: 10.12809/hkmj154667. Epub 2016 Jun 17.

25.
26.

Technique for fabrication of ultrathin foils in cylindrical geometry for liner-plasma implosion experiments with sub-megaampere currents.

Yager-Elorriaga DA, Steiner AM, Patel SG, Jordan NM, Lau YY, Gilgenbach RM.

Rev Sci Instrum. 2015 Nov;86(11):113506. doi: 10.1063/1.4935838.

PMID:
26628134
27.

Absolute Instability near the Band Edge of Traveling-Wave Amplifiers.

Hung DM, Rittersdorf IM, Zhang P, Chernin D, Lau YY, Antonsen TM, Luginsland JW, Simon DH, Gilgenbach RM.

Phys Rev Lett. 2015 Sep 18;115(12):124801. doi: 10.1103/PhysRevLett.115.124801. Epub 2015 Sep 16.

PMID:
26430996
28.

Effects of meal type on the oral bioavailability of the ALK inhibitor ceritinib in healthy adult subjects.

Lau YY, Gu W, Lin T, Song D, Yu R, Scott JW.

J Clin Pharmacol. 2016 May;56(5):559-66. doi: 10.1002/jcph.619. Epub 2015 Dec 24.

PMID:
26272586
29.

Does the environmental background (intensive v. outdoor systems) influence the behaviour of piglets at weaning?

Lau YY, Pluske JR, Fleming PA.

Animal. 2015 Aug;9(8):1361-72. doi: 10.1017/S1751731115000531. Epub 2015 Apr 22.

PMID:
25900448
30.

Diagnostic capability of low- versus high-field magnetic resonance imaging for lumbar degenerative disease.

Lee RK, Griffith JF, Lau YY, Leung JH, Ng AW, Hung EH, Law SW.

Spine (Phila Pa 1976). 2015 Mar 15;40(6):382-91. doi: 10.1097/BRS.0000000000000774.

PMID:
25584942
31.

Liquid chromatography tandem mass spectrometry method for the quantitative analysis of ceritinib in human plasma and its application to pharmacokinetic studies.

Heudi O, Vogel D, Lau YY, Picard F, Kretz O.

Anal Bioanal Chem. 2014 Nov;406(28):7389-96. doi: 10.1007/s00216-014-8125-9. Epub 2014 Sep 26.

PMID:
25258279
32.

Enterobacter asburiae strain L1: complete genome and whole genome optical mapping analysis of a quorum sensing bacterium.

Lau YY, Yin WF, Chan KG.

Sensors (Basel). 2014 Jul 30;14(8):13913-24. doi: 10.3390/s140813913.

33.

Zebrafish Adar2 Edits the Q/R site of AMPA receptor Subunit gria2α transcript to ensure normal development of nervous system and cranial neural crest cells.

Li IC, Chen YC, Wang YY, Tzeng BW, Ou CW, Lau YY, Wu KM, Chan TM, Lin WH, Hwang SP, Chow WY.

PLoS One. 2014 May 12;9(5):e97133. doi: 10.1371/journal.pone.0097133. eCollection 2014.

34.

Ceritinib in ALK-rearranged non-small-cell lung cancer.

Shaw AT, Kim DW, Mehra R, Tan DS, Felip E, Chow LQ, Camidge DR, Vansteenkiste J, Sharma S, De Pas T, Riely GJ, Solomon BJ, Wolf J, Thomas M, Schuler M, Liu G, Santoro A, Lau YY, Goldwasser M, Boral AL, Engelman JA.

N Engl J Med. 2014 Mar 27;370(13):1189-97. doi: 10.1056/NEJMoa1311107.

35.

Quorum sensing activity of Enterobacter asburiae isolated from lettuce leaves.

Lau YY, Sulaiman J, Chen JW, Yin WF, Chan KG.

Sensors (Basel). 2013 Oct 22;13(10):14189-99. doi: 10.3390/s131014189.

36.

Phosphoramidate tantalum complexes for room-temperature C-H functionalization: hydroaminoalkylation catalysis.

Garcia P, Lau YY, Perry MR, Schafer LL.

Angew Chem Int Ed Engl. 2013 Aug 26;52(35):9144-8. doi: 10.1002/anie.201304153. Epub 2013 Jul 23. No abstract available.

PMID:
23881625
37.

Novel scaling laws for the Langmuir-Blodgett solutions in cylindrical and spherical diodes.

Zhu YB, Zhang P, Valfells A, Ang LK, Lau YY.

Phys Rev Lett. 2013 Jun 28;110(26):265007. Epub 2013 Jun 28.

PMID:
23848888
38.

Single incision laparoscopic right hemicolectomy: different approaches.

Wong TM, Day W, Kwok SY, Lau YY, Yip WC.

Chin Med J (Engl). 2013 Jan;126(2):238-41.

PMID:
23324270
39.

Catalytic asymmetric synthesis of substituted morpholines and piperazines.

Zhai H, Borzenko A, Lau YY, Ahn SH, Schafer LL.

Angew Chem Int Ed Engl. 2012 Dec 3;51(49):12219-23. doi: 10.1002/anie.201206826. Epub 2012 Oct 26. No abstract available.

PMID:
23109242
40.

The effect of switchable water additives on clay settling.

Chen CS, Lau YY, Mercer SM, Robert T, Horton JH, Jessop PG.

ChemSusChem. 2013 Jan;6(1):132-40. doi: 10.1002/cssc.201200465. Epub 2012 Sep 3.

PMID:
22945593
41.

Identification and preliminary characterization of a potent, safe, and orally efficacious inhibitor of acyl-CoA:diacylglycerol acyltransferase 1.

Yeh VS, Beno DW, Brodjian S, Brune ME, Cullen SC, Dayton BD, Dhaon MK, Falls HD, Gao J, Grihalde N, Hajduk P, Hansen TM, Judd AS, King AJ, Klix RC, Larson KJ, Lau YY, Marsh KC, Mittelstadt SW, Plata D, Rozema MJ, Segreti JA, Stoner EJ, Voorbach MJ, Wang X, Xin X, Zhao G, Collins CA, Cox BF, Reilly RM, Kym PR, Souers AJ.

J Med Chem. 2012 Feb 23;55(4):1751-7. doi: 10.1021/jm201524g. Epub 2012 Feb 10.

PMID:
22263872
43.

Mechanistic modeling of antigen sink effect for mavrilimumab following intravenous administration in patients with rheumatoid arthritis.

Wang B, Lau YY, Liang M, Vainshtein I, Zusmanovich M, Lu H, Magrini F, Sleeman M, Roskos L.

J Clin Pharmacol. 2012 Aug;52(8):1150-61. doi: 10.1177/0091270011412964. Epub 2011 Sep 23.

PMID:
21947370
44.

Maintaining optimal oxygen saturation in premature infants.

Lau YY, Tay YY, Shah VA, Chang P, Loh KT.

Perm J. 2011 Winter;15(1):e108-13.

45.

Anisotropy and feedthrough in magneto-Rayleigh-Taylor instability.

Lau YY, Zier JC, Rittersdorf IM, Weis MR, Gilgenbach RM.

Phys Rev E Stat Nonlin Soft Matter Phys. 2011 Jun;83(6 Pt 2):066405. Epub 2011 Jun 14.

PMID:
21797496
46.

Genetic differentiation between fake abalone and genuine Haliotis species using the forensically informative nucleotide sequencing (FINS) method.

Ha WY, Reid DG, Kam WL, Lau YY, Sham WC, Tam SY, Sin DW, Mok CS.

J Agric Food Chem. 2011 May 25;59(10):5195-203. doi: 10.1021/jf104892n. Epub 2011 Apr 27.

PMID:
21491855
47.

Rapid aneuploidy screening with fluorescence in-situ hybridisation: is it a sufficiently robust stand-alone test for prenatal diagnosis?

Lim AS, Lim TH, Hess MM, Kee SK, Lau YY, Gilbert R, Hempel TE, Anderson KJ, Zaleski DH, Tien SL, Chia P, Subramaniam R, Tan HK, Tan AS, Sanger WG.

Hong Kong Med J. 2010 Dec;16(6):427-33.

48.

Pharmacokinetic and pharmacodynamic modeling of a monoclonal antibody antagonist of glucagon receptor in male ob/ob mice.

Lau YY, Ma P, Gibiansky L, Komorowski R, Wang J, Wang G, Yan H, Véniant MM, Kakkar T.

AAPS J. 2009 Dec;11(4):700-9. doi: 10.1208/s12248-009-9150-z. Epub 2009 Oct 23.

49.

Microwave window breakdown experiments and simulations on the UM/L-3 relativistic magnetron.

Hoff BW, Mardahl PJ, Gilgenbach RM, Haworth MD, French DM, Lau YY, Franzi M.

Rev Sci Instrum. 2009 Sep;80(9):094702. doi: 10.1063/1.3233917.

PMID:
19791954
50.

Acute glucose-lowering and insulin-sensitizing action of FGF21 in insulin-resistant mouse models--association with liver and adipose tissue effects.

Xu J, Stanislaus S, Chinookoswong N, Lau YY, Hager T, Patel J, Ge H, Weiszmann J, Lu SC, Graham M, Busby J, Hecht R, Li YS, Li Y, Lindberg R, Véniant MM.

Am J Physiol Endocrinol Metab. 2009 Nov;297(5):E1105-14. doi: 10.1152/ajpendo.00348.2009. Epub 2009 Aug 25.

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