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Aqueous Chlorination Kinetics of Cyclic Alkenes-Is HOCl the Only Chlorinating Agent that Matters?

Lau SS, Reber KP, Roberts AL.

Environ Sci Technol. 2019 Oct 1;53(19):11133-11141. doi: 10.1021/acs.est.9b01171. Epub 2019 Sep 13.


Toxicoproteomic Analysis of Poly(ADP-ribose)-associated Proteins Induced by Oxidative Stress in Human Proximal Tubule Cells.

Islas-Robles A, Yedlapudi D, Lau SS, Monks TJ.

Toxicol Sci. 2019 Jun 4. pii: kfz131. doi: 10.1093/toxsci/kfz131. [Epub ahead of print]


Concurrent Inhibition of Vesicular Monoamine Transporter 2 Does Not Protect Against 3,4-Methylenedioxymethamphetamine (Ecstasy) Induced Neurotoxicity.

Cholanians AB, Phan AV, Lau SS, Monks TJ.

Toxicol Sci. 2019 Jul 1;170(1):157-166. doi: 10.1093/toxsci/kfz085.


Cell-specific regulation of Nrf2 during ROS-Dependent cell death caused by 2,3,5-tris(glutathion-S-yl)hydroquinone (TGHQ).

Zhang F, Munoz FM, Sun L, Zhang S, Lau SS, Monks TJ.

Chem Biol Interact. 2019 Apr 1;302:1-10. doi: 10.1016/j.cbi.2019.01.027. Epub 2019 Jan 28.


Privacy and Well-Being in Aged Care Facilities with a Crowded Living Environment: Case Study of Hong Kong Care and Attention Homes.

Tao Y, Lau SSY, Gou Z, Fu J, Jiang B, Chen X.

Int J Environ Res Public Health. 2018 Oct 1;15(10). pii: E2157. doi: 10.3390/ijerph15102157.


Legibility of floor plans and wayfinding satisfaction of residents in Care and Attention homes in Hong Kong.

Tao Y, Gou Z, Lau SS, Lu Y, Fu J.

Australas J Ageing. 2018 Dec;37(4):E139-E143. doi: 10.1111/ajag.12574. Epub 2018 Aug 11.


Influence of lime and struvite on microbial community succession and odour emission during food waste composting.

Wang X, Selvam A, Lau SSS, Wong JWC.

Bioresour Technol. 2018 Jan;247:652-659. doi: 10.1016/j.biortech.2017.07.091. Epub 2017 Jul 18.


All-trans-retinoic acid-mediated cytoprotection in LLC-PK1 renal epithelial cells is coupled to p-ERK activation in a ROS-independent manner.

Sapiro JM, Monks TJ, Lau SS.

Am J Physiol Renal Physiol. 2017 Dec 1;313(6):F1200-F1208. doi: 10.1152/ajprenal.00085.2017. Epub 2017 Aug 2.


From the Cover: ROS-Induced Store-Operated Ca2+ Entry Coupled to PARP-1 Hyperactivation Is Independent of PARG Activity in Necrotic Cell Death.

Munoz FM, Zhang F, Islas-Robles A, Lau SS, Monks TJ.

Toxicol Sci. 2017 Aug 1;158(2):444-453. doi: 10.1093/toxsci/kfx106.


Chlorination Revisited: Does Cl- Serve as a Catalyst in the Chlorination of Phenols?

Lau SS, Abraham SM, Roberts AL.

Environ Sci Technol. 2016 Dec 20;50(24):13291-13298. Epub 2016 Dec 6.


Exploration of early-life candidate biomarkers for childhood asthma using antibody arrays.

Xu H, Radabaugh T, Lu Z, Galligan M, Billheimer D, Vercelli D, Wright AL, Monks TJ, Halonen M, Lau SS.

Pediatr Allergy Immunol. 2016 Nov;27(7):696-701. doi: 10.1111/pai.12613. Epub 2016 Sep 12.


From the Cover: Arsenic Induces Accumulation of α-Synuclein: Implications for Synucleinopathies and Neurodegeneration.

Cholanians AB, Phan AV, Ditzel EJ, Camenisch TD, Lau SS, Monks TJ.

Toxicol Sci. 2016 Oct;153(2):271-81. doi: 10.1093/toxsci/kfw117. Epub 2016 Jul 13.


Detection of Germline Mutation in Hereditary Breast and/or Ovarian Cancers by Next-Generation Sequencing on a Four-Gene Panel.

Kwong A, Shin VY, Au CH, Law FB, Ho DN, Ip BK, Wong AT, Lau SS, To RM, Choy G, Ford JM, Ma ES, Chan TL.

J Mol Diagn. 2016 Jul;18(4):580-94. doi: 10.1016/j.jmoldx.2016.03.005. Epub 2016 May 5.


Comparison of clinical and pathological characteristics between screen-detected and self-detected breast cancers: a Hong Kong study.

Lau SS, Cheung PS, Wong TT, Ma MK, Kwan WH.

Hong Kong Med J. 2016 Jun;22(3):202-9. doi: 10.12809/hkmj154575. Epub 2016 Mar 29.


Yin Yang 1-mediated epigenetic silencing of tumour-suppressive microRNAs activates nuclear factor-κB in hepatocellular carcinoma.

Tsang DP, Wu WK, Kang W, Lee YY, Wu F, Yu Z, Xiong L, Chan AW, Tong JH, Yang W, Li MS, Lau SS, Li X, Lee SD, Yang Y, Lai PB, Yu DY, Xu G, Lo KW, Chan MT, Wang H, Lee TL, Yu J, Wong N, Yip KY, To KF, Cheng AS.

J Pathol. 2016 Apr;238(5):651-64. doi: 10.1002/path.4688.


Metformin Scavenges Methylglyoxal To Form a Novel Imidazolinone Metabolite in Humans.

Kinsky OR, Hargraves TL, Anumol T, Jacobsen NE, Dai J, Snyder SA, Monks TJ, Lau SS.

Chem Res Toxicol. 2016 Feb 15;29(2):227-34. doi: 10.1021/acs.chemrestox.5b00497. Epub 2016 Jan 27.


Site specific modification of the human plasma proteome by methylglyoxal.

Kimzey MJ, Kinsky OR, Yassine HN, Tsaprailis G, Stump CS, Monks TJ, Lau SS.

Toxicol Appl Pharmacol. 2015 Dec 1;289(2):155-62. doi: 10.1016/j.taap.2015.09.029. Epub 2015 Oct 3.


Transcriptional and post-translational modifications of B-Raf in quinol-thioether induced tuberous sclerosis renal cell carcinoma.

Cohen JD, Labenski M, Mastrandrea NJ, Canatsey RD, Monks TJ, Lau SS.

Mol Carcinog. 2016 Aug;55(8):1243-50. doi: 10.1002/mc.22366. Epub 2015 Aug 31.


Truncated HBx-dependent silencing of GAS2 promotes hepatocarcinogenesis through deregulation of cell cycle, senescence and p53-mediated apoptosis.

Zhu R, Mok MT, Kang W, Lau SS, Yip WK, Chen Y, Lai PB, Wong VW, To KF, Sung JJ, Cheng AS, Chan HL.

J Pathol. 2015 Sep;237(1):38-49. doi: 10.1002/path.4554. Epub 2015 May 28.


The Application of Multiple Reaction Monitoring to Assess Apo A-I Methionine Oxidations in Diabetes and Cardiovascular Disease.

Yassine HN, Jackson AM, Reaven PD, Nedelkov D, Nelson RW, Lau SS, Borchers CH.

Transl Proteom. 2014 Dec 1;4-5:18-24.


Vesicular monoamine transporter 2 and the acute and long-term response to 3,4-(±)-methylenedioxymethamphetamine.

Lizarraga LE, Cholanians AB, Phan AV, Herndon JM, Lau SS, Monks TJ.

Toxicol Sci. 2015 Jan;143(1):209-19. doi: 10.1093/toxsci/kfu222. Epub 2014 Nov 4.


S-adenosyl-l-methionine protection of acetaminophen mediated oxidative stress and identification of hepatic 4-hydroxynonenal protein adducts by mass spectrometry.

Brown JM, Kuhlman C, Terneus MV, Labenski MT, Lamyaithong AB, Ball JG, Lau SS, Valentovic MA.

Toxicol Appl Pharmacol. 2014 Dec 1;281(2):174-84. doi: 10.1016/j.taap.2014.08.027. Epub 2014 Sep 22.


PARP-1 hyperactivation and reciprocal elevations in intracellular Ca2+ during ROS-induced nonapoptotic cell death.

Zhang F, Xie R, Munoz FM, Lau SS, Monks TJ.

Toxicol Sci. 2014 Jul;140(1):118-34. doi: 10.1093/toxsci/kfu073. Epub 2014 Apr 20.


Enhanced cholesterol efflux to HDL through the ABCA1 transporter in hypertriglyceridemia of type 2 diabetes.

Yassine HN, Belopolskaya A, Schall C, Stump CS, Lau SS, Reaven PD.

Metabolism. 2014 May;63(5):727-34. doi: 10.1016/j.metabol.2014.03.001. Epub 2014 Mar 5.


Catechol-o-methyltransferase and 3,4-({+/-})-methylenedioxymethamphetamine toxicity.

Herndon JM, Cholanians AB, Lizarraga LE, Lau SS, Monks TJ.

Toxicol Sci. 2014 May;139(1):162-73. doi: 10.1093/toxsci/kfu035. Epub 2014 Mar 3.


The application of multiple reaction monitoring and multi-analyte profiling to HDL proteins.

Yassine HN, Jackson AM, Borges CR, Billheimer D, Koh H, Smith D, Reaven P, Lau SS, Borchers CH.

Lipids Health Dis. 2014 Jan 8;13:8. doi: 10.1186/1476-511X-13-8.


Glial cell response to 3,4-(+/-)-methylenedioxymethamphetamine and its metabolites.

Herndon JM, Cholanians AB, Lau SS, Monks TJ.

Toxicol Sci. 2014 Mar;138(1):130-8. doi: 10.1093/toxsci/kft275. Epub 2013 Dec 3.


Mass spectrometric immunoassay and MRM as targeted MS-based quantitative approaches in biomarker development: potential applications to cardiovascular disease and diabetes.

Yassine H, Borges CR, Schaab MR, Billheimer D, Stump C, Reaven P, Lau SS, Nelson R.

Proteomics Clin Appl. 2013 Aug;7(7-8):528-40. doi: 10.1002/prca.201200028. Epub 2013 Jul 9. Review.


Reactive intermediates: molecular and MS-based approaches to assess the functional significance of chemical-protein adducts.

Monks TJ, Lau SS.

Toxicol Pathol. 2013 Feb;41(2):315-21. doi: 10.1177/0192623312467399. Epub 2012 Dec 6.


Helicobacter pylori causes epigenetic dysregulation of FOXD3 to promote gastric carcinogenesis.

Cheng AS, Li MS, Kang W, Cheng VY, Chou JL, Lau SS, Go MY, Lee CC, Ling TK, Ng EK, Yu J, Huang TH, To KF, Chan MW, Sung JJ, Chan FK.

Gastroenterology. 2013 Jan;144(1):122-133.e9. doi: 10.1053/j.gastro.2012.10.002. Epub 2012 Oct 8.


Intracranial aneurysms: midterm outcome of pipeline embolization device--a prospective study in 143 patients with 178 aneurysms.

Yu SC, Kwok CK, Cheng PW, Chan KY, Lau SS, Lui WM, Leung KM, Lee R, Cheng HK, Cheung YL, Chan CM, Wong GK, Hui JW, Wong YC, Tan CB, Poon WL, Pang KY, Wong AK, Fung KH.

Radiology. 2012 Dec;265(3):893-901. doi: 10.1148/radiol.12120422. Epub 2012 Sep 20.


A systems biology approach reveals common metastatic pathways in osteosarcoma.

Flores RJ, Li Y, Yu A, Shen J, Rao PH, Lau SS, Vannucci M, Lau CC, Man TK.

BMC Syst Biol. 2012 May 28;6:50. doi: 10.1186/1752-0509-6-50.


A dual role for poly(ADP-ribose) polymerase-1 during caspase-dependent apoptosis.

Zhang F, Lau SS, Monks TJ.

Toxicol Sci. 2012 Jul;128(1):103-14. doi: 10.1093/toxsci/kfs142. Epub 2012 Apr 20.


Adjusting for Urinary Creatinine Overestimates Arsenic Concentrations in Diabetics.

Yassine H, Kimzey MJ, Galligan MA, Gandolfi AJ, Stump CS, Lau SS.

Cardiorenal Med. 2012 Feb;2(1):26-32. Epub 2011 Dec 23.


Interdependent genotoxic mechanisms of monomethylarsonous acid: role of ROS-induced DNA damage and poly(ADP-ribose) polymerase-1 inhibition in the malignant transformation of urothelial cells.

Wnek SM, Kuhlman CL, Camarillo JM, Medeiros MK, Liu KJ, Lau SS, Gandolfi AJ.

Toxicol Appl Pharmacol. 2011 Nov 15;257(1):1-13. doi: 10.1016/j.taap.2011.08.029. Epub 2011 Sep 10.


Carboxyl-terminal truncated HBx regulates a distinct microRNA transcription program in hepatocellular carcinoma development.

Yip WK, Cheng AS, Zhu R, Lung RW, Tsang DP, Lau SS, Chen Y, Sung JG, Lai PB, Ng EK, Yu J, Wong N, To KF, Wong VW, Sung JJ, Chan HL.

PLoS One. 2011;6(8):e22888. doi: 10.1371/journal.pone.0022888. Epub 2011 Aug 4.


ERK crosstalks with 4EBP1 to activate cyclin D1 translation during quinol-thioether-induced tuberous sclerosis renal cell carcinoma.

Cohen JD, Gard JM, Nagle RB, Dietrich JD, Monks TJ, Lau SS.

Toxicol Sci. 2011 Nov;124(1):75-87. doi: 10.1093/toxsci/kfr203. Epub 2011 Aug 2.


cAMP-dependent cytosolic mislocalization of p27(kip)-cyclin D1 during quinol-thioether-induced tuberous sclerosis renal cell carcinoma.

Cohen JD, Tham KY, Mastrandrea NJ, Gallegos AC, Monks TJ, Lau SS.

Toxicol Sci. 2011 Aug;122(2):361-71. doi: 10.1093/toxsci/kfr118. Epub 2011 Jun 20.


A proposed framework for assessing risk from less-than-lifetime exposures to carcinogens.

Felter SP, Conolly RB, Bercu JP, Bolger PM, Boobis AR, Bos PM, Carthew P, Doerrer NG, Goodman JI, Harrouk WA, Kirkland DJ, Lau SS, Llewellyn GC, Preston RJ, Schoeny R, Schnatter AR, Tritscher A, van Velsen F, Williams GM.

Crit Rev Toxicol. 2011 Jul;41(6):507-44. doi: 10.3109/10408444.2011.552063. Epub 2011 May 18. Review.


The frequency of 1,4-benzoquinone-lysine adducts in cytochrome c correlate with defects in apoptosome activation.

Fisher AA, Labenski MT, Malladi S, Chapman JD, Bratton SB, Monks TJ, Lau SS.

Toxicol Sci. 2011 Jul;122(1):64-72. doi: 10.1093/toxsci/kfr085. Epub 2011 Apr 28.


EZH2-mediated concordant repression of Wnt antagonists promotes β-catenin-dependent hepatocarcinogenesis.

Cheng AS, Lau SS, Chen Y, Kondo Y, Li MS, Feng H, Ching AK, Cheung KF, Wong HK, Tong JH, Jin H, Choy KW, Yu J, To KF, Wong N, Huang TH, Sung JJ.

Cancer Res. 2011 Jun 1;71(11):4028-39. doi: 10.1158/0008-5472.CAN-10-3342. Epub 2011 Apr 21.


Optimizing microarray-based in situ transcription-translation of proteins for matrix-assisted laser desorption ionization mass spectrometry.

Kimzey MJ, Zarate X, Galbraith DW, Lau SS.

Anal Biochem. 2011 Jul 15;414(2):282-6. doi: 10.1016/j.ab.2011.03.030. Epub 2011 Apr 6.


The cytoprotective effect of N-acetyl-L-cysteine against ROS-induced cytotoxicity is independent of its ability to enhance glutathione synthesis.

Zhang F, Lau SS, Monks TJ.

Toxicol Sci. 2011 Mar;120(1):87-97. doi: 10.1093/toxsci/kfq364. Epub 2010 Dec 6.


Breast carcinoma in Chinese women: does age affect treatment choice and outcome?

Wei R, Lau SS, Cheung PS.

Asian J Surg. 2010 Apr;33(2):97-102. doi: 10.1016/S1015-9584(10)60017-6.


Identification of chemical-adducted proteins in urine by multi-dimensional protein identification technology (LC/LC-MS/MS).

Labenski MT, Fisher AA, Monks TJ, Lau SS.

Methods Mol Biol. 2011;691:339-47. doi: 10.1007/978-1-60761-849-2_21.


One-dimensional western blotting coupled to LC-MS/MS analysis to identify chemical-adducted proteins in rat urine.

Labenski MT, Fisher AA, Monks TJ, Lau SS.

Methods Mol Biol. 2011;691:327-38. doi: 10.1007/978-1-60761-849-2_20.


Utilization of LC-MS/MS analyses to identify site-specific chemical protein adducts in vitro.

Fisher AA, Labenski MT, Monks TJ, Lau SS.

Methods Mol Biol. 2011;691:317-26. doi: 10.1007/978-1-60761-849-2_19.


Utilization of MALDI-TOF to determine chemical-protein adduct formation in vitro.

Fisher AA, Labenski MT, Monks TJ, Lau SS.

Methods Mol Biol. 2011;691:303-16. doi: 10.1007/978-1-60761-849-2_18.

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