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Primary HPV testing with cytology versus cytology alone in cervical screening - a prospective randomized controlled trial (RCT) with two rounds of screening in a Chinese population.

Chan K, Liu SS, Wei N, Ngu SF, Chu M, Tse KY, Lau L, Cheung A, Ngan H.

Int J Cancer. 2020 Jan 10. doi: 10.1002/ijc.32861. [Epub ahead of print]


Optimization of a clofarabine-based drug combination regimen for the preclinical evaluation of pediatric acute lymphoblastic leukemia.

Xie J, Span M, van Maarseveen E, Langenhorst J, Boddy AV, Sia KCS, Sutton R, Venn N, Punt AM, Tyrrell V, Haber M, Trahair T, Lau L, Marshall GM, Lock RB.

Pediatr Blood Cancer. 2019 Dec 25:e28133. doi: 10.1002/pbc.28133. [Epub ahead of print]


Simultaneous Mapping of Molecular Proximity and Comobility Reveals Agonist-Enhanced Dimerization and DNA Binding of Nuclear Receptors.

Rehó B, Lau L, Mocsár G, Müller G, Fadel L, Brázda P, Nagy L, Tóth K, Vámosi G.

Anal Chem. 2020 Jan 8. doi: 10.1021/acs.analchem.9b04902. [Epub ahead of print]


Early Oxidative Stress Response in Patients with Severe Aortic Stenosis Undergoing Transcatheter and Surgical Aortic Valve Replacement: A Transatlantic Study.

Mahmoudi M, Gormaz JG, Erazo M, Howard M, Baeza C, Feelisch M, Curzen N, Olechowski B, Fernandez B, Minnion M, Mikus-Lelinska M, Meiss M, Lau L, Valls N, Gajardo AIJ, Rivotta A, Carrasco R, Cavada G, Vergara MJ, Maluenda G.

Oxid Med Cell Longev. 2019 Nov 13;2019:6217837. doi: 10.1155/2019/6217837. eCollection 2019.


Cognitive Frailty and Its Association with Nutrition and Depression in Community-Dwelling Older People.

Kwan RYC, Leung AYM, Yee A, Lau LT, Xu XY, Dai DLK.

J Nutr Health Aging. 2019;23(10):943-948. doi: 10.1007/s12603-019-1258-y.


A 10-Year Radiographic Study Comparing Anterior Versus Posterior Instrumented Spinal Fusion in Patients With Lenke Type 5 Adolescent Idiopathic Scoliosis.

Lim JL, Hey HWD, Kumar N, Teo AQA, Lau LL, Hee HT, Ruiz JN, Kumar NS, Thambiah JS, Liu GK, Wong HK.

Spine (Phila Pa 1976). 2019 Nov 18. doi: 10.1097/BRS.0000000000003331. [Epub ahead of print]


Proteomics Recapitulates Ovarian Proteins Relevant to Puberty and Fertility in Brahman Heifers (Bos indicus L.).

Tahir MS, Nguyen LT, Schulz BL, Boe-Hansen GA, Thomas MG, Moore SS, Lau LY, Fortes MRS.

Genes (Basel). 2019 Nov 12;10(11). pii: E923. doi: 10.3390/genes10110923.


Microglial motility in Alzheimer's disease and after Aβ42 immunotherapy: a human post-mortem study.

Franco-Bocanegra DK, George B, Lau LC, Holmes C, Nicoll JAR, Boche D.

Acta Neuropathol Commun. 2019 Nov 8;7(1):174. doi: 10.1186/s40478-019-0828-x.


Small RNA Species and microRNA Profiles are Altered in Severe Asthma Nanovesicles from Broncho Alveolar Lavage and Associate with Impaired Lung Function and Inflammation.

Francisco-Garcia AS, Garrido-Martín EM, Rupani H, Lau LCK, Martinez-Nunez RT, Howarth PH, Sanchez-Elsner T.

Noncoding RNA. 2019 Nov 2;5(4). pii: E51. doi: 10.3390/ncrna5040051.


Liver-Resident Memory CD8+ T Cells Form a Front-Line Defense against Malaria Liver-Stage Infection.

Fernandez-Ruiz D, Ng WY, Holz LE, Ma JZ, Zaid A, Wong YC, Lau LS, Mollard V, Cozijnsen A, Collins N, Li J, Davey GM, Kato Y, Devi S, Skandari R, Pauley M, Manton JH, Godfrey DI, Braun A, Tay SS, Tan PS, Bowen DG, Koch-Nolte F, Rissiek B, Carbone FR, Crabb BS, Lahoud M, Cockburn IA, Mueller SN, Bertolino P, McFadden GI, Caminschi I, Heath WR.

Immunity. 2019 Oct 15;51(4):780. doi: 10.1016/j.immuni.2019.09.019. No abstract available.


The use or generation of biomedical data and existing medicines to discover and establish new treatments for patients with rare diseases - recommendations of the IRDiRC Data Mining and Repurposing Task Force.

Southall NT, Natarajan M, Lau LPL, Jonker AH, Deprez B, Guilliams T, Hunter L, Rademaker CM, Hivert V, Ardigò D; IRDiRC Data Mining and Repurposing Task Force.

Orphanet J Rare Dis. 2019 Oct 15;14(1):225. doi: 10.1186/s13023-019-1193-3.


Ureter Identification In an Inflammatory Pig Model Using a Novel Near-Infrared Fluorescent Dye.

Lau LW, Luciano M, Schnermann M, Cha J.

Lasers Surg Med. 2019 Oct 3. doi: 10.1002/lsm.23165. [Epub ahead of print]


Clinical utility of echocardiography for the diagnosis of native valve infective endocarditis in Staphylococcus aureus bacteremia.

Lau L, Wiens EJ, Karlowsky JA, Keynan Y, Jassal DS.

Echocardiography. 2019 Oct;36(10):1852-1858. doi: 10.1111/echo.14480. Epub 2019 Sep 19.


The Presence of Cough and Tuberculosis: Active Case Finding Outcomes in the Philippines.

Lee S, Lau L, Lim K, Ferma J, Dodd W, Cole D.

Tuberc Res Treat. 2019 Aug 21;2019:4578329. doi: 10.1155/2019/4578329. eCollection 2019.


Amphiphilic additives in silicone oil tamponade and emulsification: an eye-on-a-chip study.

Lu Y, Chan YK, Lau LH, Wong D, Wong JKW, Shih KC, Lai SM, Shum HC.

Acta Ophthalmol. 2019 Aug 6. doi: 10.1111/aos.14212. [Epub ahead of print]


Emerging Adulthood as a Critical Stage in the Life Course.

Wood D, Crapnell T, Lau L, Bennett A, Lotstein D, Ferris M, Kuo A.

In: Halfon N, Forrest CB, Lerner RM, Faustman EM, editors. Handbook of Life Course Health Development [Internet]. Cham (CH): Springer; 2018.
2017 Nov 21.


Translating palbociclib to the clinic for DIPG - What is truly achievable?

Franshaw L, Tsoli M, Lau LMS, Ziegler DS.

EBioMedicine. 2019 Jul;45:22. doi: 10.1016/j.ebiom.2019.06.024. Epub 2019 Jun 22. No abstract available.


Prevention of recurrent idiopathic gastroduodenal ulcer bleeding: a double-blind, randomised trial.

Wong GLH, Lau LHS, Ching JYL, Tse YK, Ling RHY, Wong VWS, Chiu PWY, Lau JYW, Chan FKL.

Gut. 2019 Jun 22. pii: gutjnl-2019-318715. doi: 10.1136/gutjnl-2019-318715. [Epub ahead of print]


Faecal microbiota transplantation for treatment of recurrent or refractory Clostridioides difficile infection in Hong Kong.

Lui RN, Wong SH, Lau LHS, Chan TT, Cheung KCY, Li A, Chin ML, Tang W, Ching JYL, Lam KLY, Chan PKS, Wu JCY, Sung JJY, Chan FKL, Ng SC.

Hong Kong Med J. 2019 Jun;25(3):178-182. doi: 10.12809/hkmj197855. Epub 2019 May 29.


Liver Transplantation for Acute Liver Failure Due to Dengue Fever.

Galante A, Adeyi O, Lau L, Humar A, Galvin Z, Selzner N, Lilly L, Sapisochin G, Bhat M.

Hepatology. 2019 Nov;70(5):1863-1865. doi: 10.1002/hep.30803. Epub 2019 Aug 9. No abstract available.


Chromosomal microarray analysis is superior in identifying cryptic aberrations in patients with acute lymphoblastic leukemia at diagnosis/relapse as a single assay.

Chen C, Heng EYH, Lim AST, Lau LC, Lim TH, Wong GC, Tien SL.

Int J Lab Hematol. 2019 Aug;41(4):561-571. doi: 10.1111/ijlh.13052. Epub 2019 May 21.


CCN1-Induced Cellular Senescence Promotes Heart Regeneration.

Feng T, Meng J, Kou S, Jiang Z, Huang X, Lu Z, Zhao H, Lau LF, Zhou B, Zhang H.

Circulation. 2019 May 21;139(21):2495-2498. doi: 10.1161/CIRCULATIONAHA.119.039530. No abstract available.


Routine HbA1c among hematology and oncology inpatients: Diabetes-status and hospital-outcomes.

Chiu WL, Churilov L, Lim CH, Tan A, Nedumannil R, Lau LH, Lew J, Hachem M, Kong A, Robbins R, Sutcliffe H, Lam Q, Lee A, Djukiadmodjo F, Nanayakkara N, Zajac JD, Ekinci EI.

Diabetes Res Clin Pract. 2019 Jun;152:71-78. doi: 10.1016/j.diabres.2019.05.002. Epub 2019 May 10.


Can we reduce the number of MRSA screening site swabs in elective orthopedic patients?

Ahmad A, Teoh KH, Lau L, Cheng N, Evans AR.

J Orthop Surg (Hong Kong). 2019 May-Aug;27(2):2309499019847068. doi: 10.1177/2309499019847068.


Dual-display laparoscopic laser speckle contrast imaging for real-time surgical assistance.

Zheng C, Lau LW, Cha J.

Biomed Opt Express. 2018 Nov 5;9(12):5962-5981. doi: 10.1364/BOE.9.005962. eCollection 2018 Dec 1.


Uncoupling the Senescence-Associated Secretory Phenotype from Cell Cycle Exit via Interleukin-1 Inactivation Unveils Its Protumorigenic Role.

Lau L, Porciuncula A, Yu A, Iwakura Y, David G.

Mol Cell Biol. 2019 May 28;39(12). pii: e00586-18. doi: 10.1128/MCB.00586-18. Print 2019 Jun 15.


International collaborative actions and transparency to understand, diagnose, and develop therapies for rare diseases.

Boycott KM, Lau LP, Cutillo CM, Austin CP.

EMBO Mol Med. 2019 May;11(5). pii: e10486. doi: 10.15252/emmm.201910486. No abstract available.


Improving the adhesion, flexibility, and hemostatic efficacy of a sprayable polymer blend surgical sealant by incorporating silica particles.

Daristotle JL, Zaki ST, Lau LW, Torres L Jr, Zografos A, Srinivasan P, Ayyub OB, Sandler AD, Kofinas P.

Acta Biomater. 2019 May;90:205-216. doi: 10.1016/j.actbio.2019.04.015. Epub 2019 Apr 4.


Tonic Activation of GluN2C/GluN2D-Containing NMDA Receptors by Ambient Glutamate Facilitates Cortical Interneuron Maturation.

Hanson E, Armbruster M, Lau LA, Sommer ME, Klaft ZJ, Swanger SA, Traynelis SF, Moss SJ, Noubary F, Chadchankar J, Dulla CG.

J Neurosci. 2019 May 8;39(19):3611-3626. doi: 10.1523/JNEUROSCI.1392-18.2019. Epub 2019 Mar 7.


Reactive Species Interactome Alterations in Oocyte Donation Pregnancies in the Absence and Presence of Pre-Eclampsia.

Bos M, Schoots MH, Fernandez BO, Mikus-Lelinska M, Lau LC, Eikmans M, van Goor H, Gordijn SJ, Pasch A, Feelisch M, van der Hoorn MP.

Int J Mol Sci. 2019 Mar 6;20(5). pii: E1150. doi: 10.3390/ijms20051150.


Fortified Milk Supplementation Improves Vitamin D Status, Grip Strength, and Maintains Bone Density in Chinese Premenopausal Women Living in Malaysia.

Kruger MC, Chan YM, Lau C, Lau LT, Chin YS, Kuhn-Sherlock B, Schollum LM, Todd JM.

Biores Open Access. 2019 Mar 1;8(1):16-24. doi: 10.1089/biores.2018.0027. eCollection 2019.


NAD+ metabolism governs the proinflammatory senescence-associated secretome.

Nacarelli T, Lau L, Fukumoto T, Zundell J, Fatkhutdinov N, Wu S, Aird KM, Iwasaki O, Kossenkov AV, Schultz D, Noma KI, Baur JA, Schug Z, Tang HY, Speicher DW, David G, Zhang R.

Nat Cell Biol. 2019 Mar;21(3):397-407. doi: 10.1038/s41556-019-0287-4. Epub 2019 Feb 18.


Machine learning model to predict recurrent ulcer bleeding in patients with history of idiopathic gastroduodenal ulcer bleeding.

Wong GL, Ma AJ, Deng H, Ching JY, Wong VW, Tse YK, Yip TC, Lau LH, Liu HH, Leung CM, Tsang SW, Chan CW, Lau JY, Yuen PC, Chan FK.

Aliment Pharmacol Ther. 2019 Apr;49(7):912-918. doi: 10.1111/apt.15145. Epub 2019 Feb 13.


Variables which predict maternal self-efficacy: A hierarchical linear regression analysis.

Yap DF, Nasir N, Tan KSM, Lau LHS.

J Appl Res Intellect Disabil. 2019 Jul;32(4):841-848. doi: 10.1111/jar.12575. Epub 2019 Feb 4.


Characterization and Regulation of Carrier Proteins of Mitochondrial Glutathione Uptake in Human Retinal Pigment Epithelium Cells.

Wang M, Lau LI, Sreekumar PG, Spee C, Hinton DR, Sadda SR, Kannan R.

Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):500-516. doi: 10.1167/iovs.18-25686.


Validity of the Verbal Concept Attainment Test in multiple sclerosis.

Mulligan R, Basso MR, Lau L, Reynolds B, Whiteside DM, Combs D, Bornstein RA.

J Clin Exp Neuropsychol. 2019 May;41(4):331-340. doi: 10.1080/13803395.2018.1562048. Epub 2019 Jan 14.


Pro- and anti-tumorigenic functions of the senescence-associated secretory phenotype.

Lau L, David G.

Expert Opin Ther Targets. 2019 Dec;23(12):1041-1051. doi: 10.1080/14728222.2019.1565658. Epub 2019 Jan 15.


Advantages of a transradial vascular access for embolization of a sacral tumor in a child.

Chua YX, Yang C, Lau LL, Loh SEK.

J Vasc Access. 2019 Jul;20(4):450-451. doi: 10.1177/1129729818820197. Epub 2019 Jan 4. No abstract available.


Adhesion of silicone oil and emulsification: an in vitro assessment using a microfluidic device and 'Eye-on-a-Chip'.

Lu Y, Chan YK, Lau LH, Chao Y, Shih KC, Lai SM, Wong D, Shum HC.

Acta Ophthalmol. 2019 May;97(3):313-318. doi: 10.1111/aos.13982. Epub 2018 Nov 28.


Recommendations for the design of small population clinical trials.

Day S, Jonker AH, Lau LPL, Hilgers RD, Irony I, Larsson K, Roes KC, Stallard N.

Orphanet J Rare Dis. 2018 Nov 6;13(1):195. doi: 10.1186/s13023-018-0931-2.


Granulomatous inflammation in ginbuna crucian carp Carassius auratus langsdorfii against Mycobacterium gordonae.

Kato G, Kakazu T, Yamada M, Lau LM, Nakajima K, Sato S, Nakanishi T, Endo M, Sano M.

Dev Comp Immunol. 2019 Feb;91:93-100. doi: 10.1016/j.dci.2018.10.009. Epub 2018 Oct 29.


Validation of a prediction model for long-term outcome of aphasia after stroke.

Nouwens F, Visch-Brink EG, El Hachioui H, Lingsma HF, van de Sandt-Koenderman MWME, Dippel DWJ, Koudstaal PJ, de Lau LML.

BMC Neurol. 2018 Oct 15;18(1):170. doi: 10.1186/s12883-018-1174-5.


A novel biosimulation task trainer for the deliberate practice of resuscitative hysterotomy.

Lau L, Papanagnou D, Smith E, Waters C, Teixeira E, Zhang XC.

Adv Simul (Lond). 2018 Oct 4;3:19. doi: 10.1186/s41077-018-0078-1. eCollection 2018.


The use of 5% lidocaine medicated plaster for acute postoperative pain after gynecological surgery: A pilot randomized controlled feasibility trial.

Lau LL, Li CY, Lee A, Chan SK.

Medicine (Baltimore). 2018 Sep;97(39):e12582. doi: 10.1097/MD.0000000000012582.


Alzheimer's disease: insights for risk evaluation and prevention in the Chinese population and the need for a comprehensive programme in Hong Kong/China.

Yee A, Tsui NB, Chang YN, Au CS, Fok M, Lau LT, Chung T, Chung G, Kwan RY, Leung AY, Lau JY, Dai DL.

Hong Kong Med J. 2018 Oct;24(5):492-500. doi: 10.12809/hkmj187244. Review.


Oncogenic microRNA signature for early diagnosis of cervical intraepithelial neoplasia and cancer.

Liu SS, Chan KKL, Chu DKH, Wei TN, Lau LSK, Ngu SF, Chu MMY, Tse KY, Ip PPC, Ng EKO, Cheung ANY, Ngan HYS.

Mol Oncol. 2018 Dec;12(12):2009-2022. doi: 10.1002/1878-0261.12383. Epub 2018 Sep 27.


Brief Report: Potent clinical and radiological response to larotrectinib in TRK fusion-driven high-grade glioma.

Ziegler DS, Wong M, Mayoh C, Kumar A, Tsoli M, Mould E, Tyrrell V, Khuong-Quang DA, Pinese M, Gayevskiy V, Cohn RJ, Lau LMS, Reynolds M, Cox MC, Gifford A, Rodriguez M, Cowley MJ, Ekert PG, Marshall GM, Haber M.

Br J Cancer. 2018 Sep;119(6):693-696. doi: 10.1038/s41416-018-0251-2. Epub 2018 Sep 17.


Prevalence of diabetes and its effects on stroke outcomes: A meta-analysis and literature review.

Lau LH, Lew J, Borschmann K, Thijs V, Ekinci EI.

J Diabetes Investig. 2019 May;10(3):780-792. doi: 10.1111/jdi.12932. Epub 2018 Oct 13. Review.

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