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Unique anabolic action of stem cell gene therapy overexpressing PDGFB-DSS6 fusion protein in OVX osteoporosis mouse model.

Chen W, Wasnik S, Fu Y, Aranda L, Rundle CH, Lau KW, Baylink DJ, Zhang X.

Bone Rep. 2019 Dec 11;12:100236. doi: 10.1016/j.bonr.2019.100236. eCollection 2020 Jun.


Mechanistic study of the cause of decreased blood 1,25-Dihydroxyvitamin D in sepsis.

Li CH, Tang X, Wasnik S, Wang X, Zhang J, Xu Y, Lau KW, Nguyen HB, Baylink DJ.

BMC Infect Dis. 2019 Dec 2;19(1):1020. doi: 10.1186/s12879-019-4529-7.


Calcitonin Gene-Related Peptide in Blind, Painful Eyes.

Godbout EE, Lau KW, Adam AP, Wladis EJ.

Ophthalmic Plast Reconstr Surg. 2019 Nov 15. doi: 10.1097/IOP.0000000000001512. [Epub ahead of print]


A new black fly species of Simulium (Gomphostilbia) (Diptera: Simuliidae) br />from Sulawesi, Indonesia.

Takaoka H, Sofian-Azirun M, Chen CD, Halim MRA, Lau KW, Low VL, Suana IW.

Zootaxa. 2019 Aug 5;4651(2):zootaxa.4651.2.12. doi: 10.11646/zootaxa.4651.2.12.


A Mouse Noninvasive Intraarticular Tibial Plateau Compression Loading-Induced Injury Model of Posttraumatic Osteoarthritis.

Stiffel V, Rundle CH, Sheng MH, Das S, Lau KW.

Calcif Tissue Int. 2020 Feb;106(2):158-171. doi: 10.1007/s00223-019-00614-0. Epub 2019 Sep 26.


Cyclooxygenase 2 augments osteoblastic but suppresses chondrocytic differentiation of CD90+ skeletal stem cells in fracture sites.

Wasnik S, Lakhan R, Baylink DJ, Rundle CH, Xu Y, Zhang J, Qin X, Lau KW, Carreon EE, Tang X.

Sci Adv. 2019 Jul 31;5(7):eaaw2108. doi: 10.1126/sciadv.aaw2108. eCollection 2019 Jul.


Adulticide Resistance Status of Aedes albopictus (Diptera: Culicidae) in Sabah, Malaysia: A Statewide Assessment.

Elia-Amira NMR, Chen CD, Low VL, Lau KW, Haziqah-Rashid A, Amelia-Yap ZH, Lee HL, Sofian-Azirun M.

J Med Entomol. 2019 Oct 28;56(6):1715-1725. doi: 10.1093/jme/tjz117.


A simple method to allow for guanine-cytosine amplification error in prenatal DNA screening for trisomy 18.

Wald NJ, Bestwick JP, Lau KW, Huttly WJ, Ke W, Cheng R, Old RW.

Clin Chim Acta. 2019 Sep;496:13-17. doi: 10.1016/j.cca.2019.06.015. Epub 2019 Jun 15.


In Vivo Generation of Gut-Homing Regulatory T Cells for the Suppression of Colitis.

Xu Y, Cheng Y, Baylink DJ, Wasnik S, Goel G, Huang M, Cao H, Qin X, Lau KW, Chan C, Koch A, Pham LH, Zhang J, Li CH, Wang X, Berumen EC, Smith J, Tang X.

J Immunol. 2019 Jun 15;202(12):3447-3457. doi: 10.4049/jimmunol.1800018. Epub 2019 May 3.


V1016G Point Mutation: The Key Mutation in the Voltage-Gated Sodium Channel (Vgsc) Gene of Pyrethroid-Resistant Aedes aegypti (Diptera: Culicidae) in Indonesia.

Amelia-Yap ZH, Sofian-Azirun M, Chen CD, Lau KW, Suana IW, Syahputra E, Razak A, Low VL.

J Med Entomol. 2019 Jun 27;56(4):953-958. doi: 10.1093/jme/tjz035.


Pyrethroids Use: Threats on Metabolic-Mediated Resistance Mechanisms in the Primary Dengue Vector Aedes aegypti (Diptera: Culicidae).

Amelia-Yap ZH, Sofian-Azirun M, Chen CD, Suana IW, Lau KW, Elia-Amira NMR, Haziqah-Rashid A, Tan TK, Lim YAL, Low VL.

J Med Entomol. 2019 Apr 16;56(3):811-816. doi: 10.1093/jme/tjz007.


Antibiotic management of acute pharyngitis in primary care.

Advisory Group on Antibiotic Stewardship Programme in Primary Care, Chan AMW, Au WWY, Chao DVK, Choi K, Choi KW, Choi SMY, Chow Y, Fan CYM, Ho PL, Hui EMT, Kwong KH, Kwong BYS, Lam TP, Lam ETK, Lau KW, Lui L, Ng KHL, Wong MCS, Wong TY, Yeung CF, You JHS, Yung RWH.

Hong Kong Med J. 2019 Feb;25(1):58-63. doi: 10.12809/hkmj187544. Epub 2019 Jan 31.


Nuclear Factor Kappa-B Is Enriched in Eyelid Specimens of Rosacea: Implications for Pathogenesis and Therapy.

Wladis EJ, Lau KW, Adam AP.

Am J Ophthalmol. 2019 May;201:72-81. doi: 10.1016/j.ajo.2019.01.018. Epub 2019 Jan 28.


A New Black Fly Species of the Simulium (Gomphostilbia) duolongum Subgroup (Diptera: Simuliidae) From Vietnam, and Molecular Comparisons With Related Species Using the COI Barcoding Gene.

Takaoka H, Low VL, Tan TK, Ya'cob Z, Sofian-Azirun M, Dhang Chen C, Lau KW, Da Pham X.

J Med Entomol. 2019 Feb 25;56(2):432-440. doi: 10.1093/jme/tjy222.


A new black fly species of Simulium (Nevermannia) (Diptera: Simuliidae) from Vietnam.

Takaoka H, Low VL, Tan TK, Sofian-Azirun M, Chen CD, Lau KW, Pham XD.

Acta Trop. 2019 Feb;190:320-328. doi: 10.1016/j.actatropica.2018.11.025. Epub 2018 Nov 26.


Monitoring Insecticide Resistance Profiles of Aedes aegypti (Diptera: Culicidae) in the Sunda Islands of Indonesia Based on Diagnostic Doses of Larvicides.

Haziqah-Rashid A, Chen CD, Lau KW, Low VL, Sofian-Azirun M, Suana IW, Harmonis H, Syahputra E, Razak A, Chin AC, Azidah AA.

J Med Entomol. 2019 Feb 25;56(2):514-518. doi: 10.1093/jme/tjy208.


Efficacy of Mosquito Coils: Cross-resistance to Pyrethroids in Aedes aegypti (Diptera: Culicidae) From Indonesia.

Amelia-Yap ZH, Chen CD, Sofian-Azirun M, Lau KW, Suana IW, Harmonis, Syahputra E, Razak A, Low VL.

J Econ Entomol. 2018 Dec 14;111(6):2854-2860. doi: 10.1093/jee/toy296.


1,25-Dihydroxyvitamin D suppresses M1 macrophages and promotes M2 differentiation at bone injury sites.

Wasnik S, Rundle CH, Baylink DJ, Yazdi MS, Carreon EE, Xu Y, Qin X, Lau KW, Tang X.

JCI Insight. 2018 Sep 6;3(17). pii: 98773. doi: 10.1172/jci.insight.98773. eCollection 2018 Sep 6.


Bioefficacy Evaluation of Commercial Mosquito Coils Containing Metofluthrin, d-Allethrin, d-Trans Allethrin, and Prallethrin Against Aedes albopictus (Diptera: Culicidae) in Malaysia.

Chen CD, Chin AC, Lau KW, Low VL, Lee HL, Lee PKY, Azidah AA, Sofian-Azirun M.

J Med Entomol. 2018 Oct 25;55(6):1651-1655. doi: 10.1093/jme/tjy130.


Establishing an anaesthetist-delivered propofol sedation service for advanced endoscopic procedures: implementing the RCA/BSG guidelines.

Smith I, Durkin D, Lau KW, Hebbar S.

Frontline Gastroenterol. 2018 Jul;9(3):185-191. doi: 10.1136/flgastro-2017-100839. Epub 2017 Nov 2.


Organophosphate and Organochlorine Resistance in Larval Stage of Aedes albopictus (Diptera: Culicidae) in Sabah, Malaysia.

Elia-Amira NMR, Chen CD, Lau KW, Lee HL, Low VL, Norma-Rashid Y, Sofian-Azirun M.

J Econ Entomol. 2018 Sep 26;111(5):2488-2492. doi: 10.1093/jee/toy184.


Specifying a Gold Standard for the Validation of Fetal Fraction Estimation in Prenatal Screening.

Wald NJ, Lau KW, Bestwick JP, Old RW, Huttly WJ, Cheng R.

Clin Chem. 2018 Sep;64(9):1394-1399. doi: 10.1373/clinchem.2018.288670. Epub 2018 Jun 26.


A novel miR17/protein tyrosine phosphatase-oc/EphA4 regulatory axis of osteoclast activity.

Lau KW, Sheng MH.

Arch Biochem Biophys. 2018 Jul 15;650:30-38. doi: 10.1016/ Epub 2018 May 17. Review.


Bioefficacy of Insect Growth Regulators Against Aedes albopictus (Diptera: Culicidea) From Sarawak, Malaysia: A Statewide Survey.

Lau KW, Chen CD, Lee HL, Low VL, Sofian-Azirun M.

J Econ Entomol. 2018 May 28;111(3):1388-1394. doi: 10.1093/jee/toy071.


Deficient arginase II expression without alteration in arginase I expression attenuated experimental autoimmune encephalomyelitis in mice.

Choudry M, Tang X, Santorian T, Wasnik S, Xiao J, Xing W, Lau KW, Mohan S, Baylink DJ, Qin X.

Immunology. 2018 Sep;155(1):85-98. doi: 10.1111/imm.12926. Epub 2018 Apr 16.


Successful removal of a penoscrotal constricting ring in a 49-year-old male.

Lu Y, Tan TW, Lau KW.

Asian J Urol. 2017 Oct;4(4):262-264. doi: 10.1016/j.ajur.2017.01.003. Epub 2017 Mar 6.


Expanded molecular interrogation for potential actionable targets in non-squamous non-small cell lung cancer.

Lau KW, Seng C, Lim TKH, Tan DSW.

Ann Transl Med. 2017 Sep;5(18):372. doi: 10.21037/atm.2017.08.42. Review.


Comparative Efficacy of Commercial Mosquito Coils Against Aedes aegypti (Diptera: Culicidae) in Malaysia: A Nationwide Report.

Chin AC, Chen CD, Low VL, Lee HL, Azidah AA, Lau KW, Sofian-Azirun M.

J Econ Entomol. 2017 Oct 1;110(5):2247-2251. doi: 10.1093/jee/tox183.


Rates and predictors of disengagement of patients with first-episode psychosis from the early intervention service for sychosis service (EASY) covering 15 to 64 years of age in Hong Kong.

Lau KW, Chan SKW, Hui CLM, Lee EHM, Chang WC, Chong CS, Lo WT, Chen EYH.

Early Interv Psychiatry. 2019 Jun;13(3):398-404. doi: 10.1111/eip.12491. Epub 2017 Oct 6.


RNA editing of AZIN1 induces the malignant progression of non-small-cell lung cancers.

Hu X, Chen J, Shi X, Feng F, Lau KW, Chen Y, Chen Y, Jiang L, Cui F, Zhang Y, Xu X, Li J.

Tumour Biol. 2017 Aug;39(8):1010428317700001. doi: 10.1177/1010428317700001.


The black flies (Diptera: Simuliidae) of Vietnam.

Takaoka H, Sofian-Azirun M, Ya'cob Z, Chen CD, Lau KW, Low VL, Pham XD, Adler PH.

Zootaxa. 2017 May 5;4261(1):1-165. doi: 10.11646/zootaxa.4261.1.1.


Dendritic cells, engineered to overexpress 25-hydroxyvitamin D 1α-hydroxylase and pulsed with a myelin antigen, provide myelin-specific suppression of ongoing experimental allergic encephalomyelitis.

Li CH, Zhang J, Baylink DJ, Wang X, Goparaju NB, Xu Y, Wasnik S, Cheng Y, Berumen EC, Qin X, Lau KW, Tang X.

FASEB J. 2017 Jul;31(7):2996-3006. doi: 10.1096/fj.201601243R. Epub 2017 Mar 31.


Unique Regenerative Mechanism to Replace Bone Lost During Dietary Bone Depletion in Weanling Mice.

Sheng MH, Lau KW, Lakhan R, Ahmed ASI, Rundle CH, Biswanath P, Baylink DJ.

Endocrinology. 2017 Apr 1;158(4):714-729. doi: 10.1210/en.2016-1379.


<i>Simulium</i> (<i>Gomphostilbia</i>) <i>lemborense</i>, a new black fly species (Diptera: Simuliidae) from Flores, Indonesia.

Takaoka H, Sofian-Azirun M, Chen CD, Lau KW, Halim MR, Low VL, Ya'cob Z, Abdullah NA, Suana IW.

Zootaxa. 2017 Feb 21;4236(1):zootaxa.4236.1.8. doi: 10.11646/zootaxa.4236.1.8.


Incidental Multiple Pulmonary Nodules in a Middle-Aged Woman.

Lee KC, Lau KW.

Ann Acad Med Singapore. 2017 Feb;46(2):79-80. No abstract available.


Effect of aging on stem cells.

Ahmed AS, Sheng MH, Wasnik S, Baylink DJ, Lau KW.

World J Exp Med. 2017 Feb 20;7(1):1-10. doi: 10.5493/wjem.v7.i1.1. eCollection 2017 Feb 20. Review.


The black flies (Diptera: Simuliidae) of the Lesser Sunda Archipelago, Indonesia.

Takaoka H, Sofian-Azirun M, Ya'cob Z, Chen CD, Lau KW, Low VL, Suana IW.

Acta Trop. 2017 May;169:170-186. doi: 10.1016/j.actatropica.2017.01.016. Epub 2017 Jan 23.


Two New Species of Simulium (Gomphostilbia) (Diptera: Simuliidae) From Flores, Indonesia.

Takaoka H, Sofian-Azirun M, Chen CD, Lau KW, Halim MRA, Low VL, Ya'cob Z, Abdullah NA, Suana IW.

J Med Entomol. 2017 May 1;54(3):576-586. doi: 10.1093/jme/tjw208.


No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis.

Loley C, Alver M, Assimes TL, Bjonnes A, Goel A, Gustafsson S, Hernesniemi J, Hopewell JC, Kanoni S, Kleber ME, Lau KW, Lu Y, Lyytikäinen LP, Nelson CP, Nikpay M, Qu L, Salfati E, Scholz M, Tukiainen T, Willenborg C, Won HH, Zeng L, Zhang W, Anand SS, Beutner F, Bottinger EP, Clarke R, Dedoussis G, Do R, Esko T, Eskola M, Farrall M, Gauguier D, Giedraitis V, Granger CB, Hall AS, Hamsten A, Hazen SL, Huang J, Kähönen M, Kyriakou T, Laaksonen R, Lind L, Lindgren C, Magnusson PK, Marouli E, Mihailov E, Morris AP, Nikus K, Pedersen N, Rallidis L, Salomaa V, Shah SH, Stewart AF, Thompson JR, Zalloua PA, Chambers JC, Collins R, Ingelsson E, Iribarren C, Karhunen PJ, Kooner JS, Lehtimäki T, Loos RJ, März W, McPherson R, Metspalu A, Reilly MP, Ripatti S, Sanghera DK, Thiery J, Watkins H, Deloukas P, Kathiresan S, Samani NJ, Schunkert H, Erdmann J, König IR.

Sci Rep. 2016 Oct 12;6:35278. doi: 10.1038/srep35278.


Vietnam, a Hotspot for Chromosomal Diversity and Cryptic Species in Black Flies (Diptera: Simuliidae).

Adler PH, Takaoka H, Sofian-Azirun M, Low VL, Ya'cob Z, Chen CD, Lau KW, Pham XD.

PLoS One. 2016 Oct 3;11(10):e0163881. doi: 10.1371/journal.pone.0163881. eCollection 2016.


Conditional deletion of IGF-I in osteocytes unexpectedly accelerates bony union of the fracture gap in mice.

Lau KW, Rundle CH, Zhou XD, Baylink DJ, Sheng MH.

Bone. 2016 Nov;92:18-28. doi: 10.1016/j.bone.2016.08.005. Epub 2016 Aug 9.


Bidirectional ephrin signaling in bone.

Rundle CH, Xing W, Lau KW, Mohan S.

Osteoporos Sarcopenia. 2016 Jun;2(2):65-76. doi: 10.1016/j.afos.2016.05.002. Epub 2016 Jun 7. Review.


The curious incident of 3 melanomas and their possible origins-A case report and review of literature.

Sin EI, Tan BK, Lau KW, Teo MC.

Int J Surg Case Rep. 2016;23:77-81. doi: 10.1016/j.ijscr.2016.04.020. Epub 2016 Apr 13.


Socio-economic status and lifestyle factors are associated with achalasia risk: A population-based case-control study.

Coleman HG, Gray RT, Lau KW, McCaughey C, Coyle PV, Murray LJ, Johnston BT.

World J Gastroenterol. 2016 Apr 21;22(15):4002-8. doi: 10.3748/wjg.v22.i15.4002.


Dimorphic male scutal patterns and upper-eye facets of Simulium mirum n. sp. (Diptera: Simuliidae) from Malaysia.

Takaoka H, Low VL, Sofian-Azirun M, Otsuka Y, Ya'cob Z, Chen CD, Lau KW, Lardizabal ML.

Parasit Vectors. 2016 Mar 9;9:136. doi: 10.1186/s13071-016-1393-9.



Nurin-Zulkifli IM, Chen CD, Wan-Norafikah O, Lee HL, Faezah K, Izzul AA, Abdullah AG, Lau KW, Norma-Rashid Y, Sofian-Azirun M.

Southeast Asian J Trop Med Public Health. 2015 Jul;46(4):574-85.


Ciliated muconodular papillary tumor: a solitary peripheral lung nodule in a teenage girl.

Lau KW, Aubry MC, Tan GS, Lim CH, Takano AM.

Hum Pathol. 2016 Mar;49:22-6. doi: 10.1016/j.humpath.2015.09.038. Epub 2015 Oct 28.


Heller's myotomy and pneumatic dilatation in the treatment of achalasia: a population-based case-control study assessing long-term quality of life.

Gray RT, Coleman HG, Lau KW, McCaughey C, Coyle PV, Murray LJ, Johnston BT.

Dis Esophagus. 2017 Feb 1;30(3):1-7. doi: 10.1111/dote.12445.


A comprehensive 1,000 Genomes-based genome-wide association meta-analysis of coronary artery disease.

Nikpay M, Goel A, Won HH, Hall LM, Willenborg C, Kanoni S, Saleheen D, Kyriakou T, Nelson CP, Hopewell JC, Webb TR, Zeng L, Dehghan A, Alver M, Armasu SM, Auro K, Bjonnes A, Chasman DI, Chen S, Ford I, Franceschini N, Gieger C, Grace C, Gustafsson S, Huang J, Hwang SJ, Kim YK, Kleber ME, Lau KW, Lu X, Lu Y, Lyytikäinen LP, Mihailov E, Morrison AC, Pervjakova N, Qu L, Rose LM, Salfati E, Saxena R, Scholz M, Smith AV, Tikkanen E, Uitterlinden A, Yang X, Zhang W, Zhao W, de Andrade M, de Vries PS, van Zuydam NR, Anand SS, Bertram L, Beutner F, Dedoussis G, Frossard P, Gauguier D, Goodall AH, Gottesman O, Haber M, Han BG, Huang J, Jalilzadeh S, Kessler T, König IR, Lannfelt L, Lieb W, Lind L, Lindgren CM, Lokki ML, Magnusson PK, Mallick NH, Mehra N, Meitinger T, Memon FU, Morris AP, Nieminen MS, Pedersen NL, Peters A, Rallidis LS, Rasheed A, Samuel M, Shah SH, Sinisalo J, Stirrups KE, Trompet S, Wang L, Zaman KS, Ardissino D, Boerwinkle E, Borecki IB, Bottinger EP, Buring JE, Chambers JC, Collins R, Cupples LA, Danesh J, Demuth I, Elosua R, Epstein SE, Esko T, Feitosa MF, Franco OH, Franzosi MG, Granger CB, Gu D, Gudnason V, Hall AS, Hamsten A, Harris TB, Hazen SL, Hengstenberg C, Hofman A, Ingelsson E, Iribarren C, Jukema JW, Karhunen PJ, Kim BJ, Kooner JS, Kullo IJ, Lehtimäki T, Loos RJF, Melander O, Metspalu A, März W, Palmer CN, Perola M, Quertermous T, Rader DJ, Ridker PM, Ripatti S, Roberts R, Salomaa V, Sanghera DK, Schwartz SM, Seedorf U, Stewart AF, Stott DJ, Thiery J, Zalloua PA, O'Donnell CJ, Reilly MP, Assimes TL, Thompson JR, Erdmann J, Clarke R, Watkins H, Kathiresan S, McPherson R, Deloukas P, Schunkert H, Samani NJ, Farrall M.

Nat Genet. 2015 Oct;47(10):1121-1130. doi: 10.1038/ng.3396. Epub 2015 Sep 7.

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