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Items: 38


Increased PHGDH expression promotes aberrant melanin accumulation.

Mattaini KR, Sullivan MR, Lau AN, Fiske BP, Bronson RT, Vander Heiden MG.

BMC Cancer. 2019 Jul 22;19(1):723. doi: 10.1186/s12885-019-5933-5.


Putting the K+ in K+aloric Restriction.

Lien EC, Lau AN, Vander Heiden MG.

Immunity. 2019 May 21;50(5):1129-1131. doi: 10.1016/j.immuni.2019.04.016.


Effect of Concomitant Disease-modifying Antirheumatic Drugs and Methotrexate Administration Route on Biologic Treatment Durability in Rheumatoid Arthritis: OBRI Cohort Results.

Lau AN, Thorne JC, Movahedi M, Rampakakis E, Cesta A, Li X, Couto S, Sampalis J, Bombardier C; OBRI Investigators.

J Rheumatol. 2019 Aug;46(8):874-886. doi: 10.3899/jrheum.180486. Epub 2019 Apr 15.


PKM2 is not required for pancreatic ductal adenocarcinoma.

Hillis AL, Lau AN, Devoe CX, Dayton TL, Danai LV, Di Vizio D, Vander Heiden MG.

Cancer Metab. 2018 Oct 23;6:17. doi: 10.1186/s40170-018-0188-1. eCollection 2018.


JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition.

McKenney AS, Lau AN, Somasundara AVH, Spitzer B, Intlekofer AM, Ahn J, Shank K, Rapaport FT, Patel MA, Papalexi E, Shih AH, Chiu A, Freinkman E, Akbay EA, Steadman M, Nagaraja R, Yen K, Teruya-Feldstein J, Wong KK, Rampal R, Vander Heiden MG, Thompson CB, Levine RL.

J Clin Invest. 2018 Oct 1;128(10):4743. doi: 10.1172/JCI124920. Epub 2018 Sep 17. No abstract available.


Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting.

Alkan HF, Walter KE, Luengo A, Madreiter-Sokolowski CT, Stryeck S, Lau AN, Al-Zoughbi W, Lewis CA, Thomas CJ, Hoefler G, Graier WF, Madl T, Vander Heiden MG, Bogner-Strauss JG.

Cell Metab. 2018 Nov 6;28(5):706-720.e6. doi: 10.1016/j.cmet.2018.07.021. Epub 2018 Aug 16.


Aspartate is an endogenous metabolic limitation for tumour growth.

Sullivan LB, Luengo A, Danai LV, Bush LN, Diehl FF, Hosios AM, Lau AN, Elmiligy S, Malstrom S, Lewis CA, Vander Heiden MG.

Nat Cell Biol. 2018 Jul;20(7):782-788. doi: 10.1038/s41556-018-0125-0. Epub 2018 Jun 25.


Altered exocrine function can drive adipose wasting in early pancreatic cancer.

Danai LV, Babic A, Rosenthal MH, Dennstedt EA, Muir A, Lien EC, Mayers JR, Tai K, Lau AN, Jones-Sali P, Prado CM, Petersen GM, Takahashi N, Sugimoto M, Yeh JJ, Lopez N, Bardeesy N, Fernandez-Del Castillo C, Liss AS, Koong AC, Bui J, Yuan C, Welch MW, Brais LK, Kulke MH, Dennis C, Clish CB, Wolpin BM, Vander Heiden MG.

Nature. 2018 Jun;558(7711):600-604. doi: 10.1038/s41586-018-0235-7. Epub 2018 Jun 20.


JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition.

McKenney AS, Lau AN, Somasundara AVH, Spitzer B, Intlekofer AM, Ahn J, Shank K, Rapaport FT, Patel MA, Papalexi E, Shih AH, Chiu A, Freinkman E, Akbay EA, Steadman M, Nagaraja R, Yen K, Teruya-Feldstein J, Wong KK, Rampal R, Vander Heiden MG, Thompson CB, Levine RL.

J Clin Invest. 2018 Feb 1;128(2):789-804. doi: 10.1172/JCI94516. Epub 2018 Jan 22. Erratum in: J Clin Invest. 2018 Oct 1;128(10):4743.


Corrigendum to "The Current Practice of Screening, Prevention, and Treatment of Androgen-Deprivation-Therapy Induced Osteoporosis in Patients with Prostate Cancer".

Al-Shamsi HO, Lau AN, Malik K, Alamri A, Ioannidis G, Corbett T, Adachi JD, Papaioannou A.

J Oncol. 2017;2017:3432604. doi: 10.1155/2017/3432604. Epub 2017 Dec 3.


PKM2 is not required for colon cancer initiated by APC loss.

Lau AN, Israelsen WJ, Roper J, Sinnamon MJ, Georgeon L, Dayton TL, Hillis AL, Yilmaz OH, Di Vizio D, Hung KE, Vander Heiden MG.

Cancer Metab. 2017 Nov 30;5:10. doi: 10.1186/s40170-017-0172-1. eCollection 2017.


Occurrence of Serious Infection in Patients with Rheumatoid Arthritis Treated with Biologics and Denosumab Observed in a Clinical Setting.

Lau AN, Wong-Pack M, Rodjanapiches R, Ioannidis G, Wade S, Spangler L, Balasubramanian A, Pannacciulli N, Lin CJF, Roy-Gayos P, Bensen WG, Bensen R, Adachi JD.

J Rheumatol. 2018 Feb;45(2):170-176. doi: 10.3899/jrheum.161270. Epub 2017 Nov 15.


The effect of bariatric surgery on serum 25-OH vitamin D levels: a systematic review and meta-analysis.

Kalani A, Bami H, Tiboni M, Jaeschke R, Adachi JD, Lau AN.

Obes Sci Pract. 2017 Jun 27;3(3):319-332. doi: 10.1002/osp4.113. eCollection 2017 Sep.


Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.

Mayers JR, Torrence ME, Danai LV, Papagiannakopoulos T, Davidson SM, Bauer MR, Lau AN, Ji BW, Dixit PD, Hosios AM, Muir A, Chin CR, Freinkman E, Jacks T, Wolpin BM, Vitkup D, Vander Heiden MG.

Science. 2016 Sep 9;353(6304):1161-5. doi: 10.1126/science.aaf5171.


Predicting low testosterone in aging men: a systematic review.

Millar AC, Lau ANC, Tomlinson G, Kraguljac A, Simel DL, Detsky AS, Lipscombe LL.

CMAJ. 2016 Sep 20;188(13):E321-E330. doi: 10.1503/cmaj.150262. Epub 2016 Jun 20. Review.


Incentivizing health care behaviors in emerging adults: a systematic review.

Yu CH, Guarna G, Tsao P, Jesuthasan JR, Lau AN, Siddiqi FS, Gilmour JA, Ladha D, Halapy H, Advani A.

Patient Prefer Adherence. 2016 Mar 24;10:371-81. doi: 10.2147/PPA.S102574. eCollection 2016.


The Effects of Noncompliance to Prolia (Denosumab) on the Changes in Bone Mineral Density: A Retrospective Review.

Wong-Pack M, Kalani A, Hordyk J, Ioannidis G, Bensen R, Bensen WG, Papaioannou A, Adachi JD, Lau AN.

J Osteoporos. 2016;2016:7903128. doi: 10.1155/2016/7903128. Epub 2016 Jan 4.


Stopping the Clock with MYC.

Lau AN, Vander Heiden MG.

Mol Cell. 2015 Nov 19;60(4):511-3. doi: 10.1016/j.molcel.2015.11.008.


The Tissue-Selective Estrogen Complex: A Review of Current Evidence.

Pazhekattu R, Lau AN, Adachi JD.

Rheumatol Ther. 2015 Jun;2(1):47-58. Epub 2015 May 20. Review.


The relationship between long-term proton pump inhibitor therapy and skeletal frailty.

Lau AN, Tomizza M, Wong-Pack M, Papaioannou A, Adachi JD.

Endocrine. 2015 Aug;49(3):606-10. doi: 10.1007/s12020-015-0576-z. Epub 2015 May 7. Review.


Neurotrophin receptor TrkB promotes lung adenocarcinoma metastasis.

Sinkevicius KW, Kriegel C, Bellaria KJ, Lee J, Lau AN, Leeman KT, Zhou P, Beede AM, Fillmore CM, Caswell D, Barrios J, Wong KK, Sholl LM, Schlaeger TM, Bronson RT, Chirieac LR, Winslow MM, Haigis MC, Kim CF.

Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10299-304. doi: 10.1073/pnas.1404399111. Epub 2014 Jun 30.


Tumor-propagating cells and Yap/Taz activity contribute to lung tumor progression and metastasis.

Lau AN, Curtis SJ, Fillmore CM, Rowbotham SP, Mohseni M, Wagner DE, Beede AM, Montoro DT, Sinkevicius KW, Walton ZE, Barrios J, Weiss DJ, Camargo FD, Wong KK, Kim CF.

EMBO J. 2014 Mar 3;33(5):468-81. doi: 10.1002/embj.201386082. Epub 2014 Feb 4. Erratum in: EMBO J. 2014 Jul 1;33(13):1502.


The current practice of screening, prevention, and treatment of androgen-deprivation-therapy induced osteoporosis in patients with prostate cancer.

Al-Shamsi HO, Lau AN, Malik K, Alamri A, Ioannidis G, Corbett T, Adachi JD, Papaioannou A.

J Oncol. 2012;2012:958596. doi: 10.1155/2012/958596. Epub 2012 Apr 30. Erratum in: J Oncol. 2017;2017:3432604.


Isolation and characterization of distal lung progenitor cells.

Driscoll B, Kikuchi A, Lau AN, Lee J, Reddy R, Jesudason E, Kim CF, Warburton D.

Methods Mol Biol. 2012;879:109-22. doi: 10.1007/978-1-61779-815-3_7.


Initiating insulin in patients with type 2 diabetes.

Lau AN, Tang T, Halapy H, Thorpe K, Yu CH.

CMAJ. 2012 Apr 17;184(7):767-76. doi: 10.1503/cmaj.110779. Epub 2012 Apr 2. Review. No abstract available. Erratum in: CMAJ. 2012 May 15;184(8):922.


Stem cells and regenerative medicine in lung biology and diseases.

Lau AN, Goodwin M, Kim CF, Weiss DJ.

Mol Ther. 2012 Jun;20(6):1116-30. doi: 10.1038/mt.2012.37. Epub 2012 Mar 6. Review.


Bronchioalveolar stem cells increase after mesenchymal stromal cell treatment in a mouse model of bronchopulmonary dysplasia.

Tropea KA, Leder E, Aslam M, Lau AN, Raiser DM, Lee JH, Balasubramaniam V, Fredenburgh LE, Alex Mitsialis S, Kourembanas S, Kim CF.

Am J Physiol Lung Cell Mol Physiol. 2012 May 1;302(9):L829-37. doi: 10.1152/ajplung.00347.2011. Epub 2012 Feb 10.


Lung stem cell self-renewal relies on BMI1-dependent control of expression at imprinted loci.

Zacharek SJ, Fillmore CM, Lau AN, Gludish DW, Chou A, Ho JW, Zamponi R, Gazit R, Bock C, J├Ąger N, Smith ZD, Kim TM, Saunders AH, Wong J, Lee JH, Roach RR, Rossi DJ, Meissner A, Gimelbrant AA, Park PJ, Kim CF.

Cell Stem Cell. 2011 Sep 2;9(3):272-81. doi: 10.1016/j.stem.2011.07.007.


Role of teriparatide in treatment of glucocorticoid-induced osteoporosis.

Lau AN, Adachi JD.

Ther Clin Risk Manag. 2010 Oct 21;6:497-503. doi: 10.2147/TCRM.S7776.


What are the beliefs, attitudes and practices of front-line staff in long-term care (LTC) facilities related to osteoporosis awareness, management and fracture prevention?

Lau AN, Ioannidis G, Potts Y, Giangregorio LM, Van der Horst ML, Adachi JD, Papaioannou A.

BMC Geriatr. 2010 Oct 8;10:73. doi: 10.1186/1471-2318-10-73.


Primary tumor genotype is an important determinant in identification of lung cancer propagating cells.

Curtis SJ, Sinkevicius KW, Li D, Lau AN, Roach RR, Zamponi R, Woolfenden AE, Kirsch DG, Wong KK, Kim CF.

Cell Stem Cell. 2010 Jul 2;7(1):127-33. doi: 10.1016/j.stem.2010.05.021.


Antifouling coatings for optoelectronic tweezers.

Lau AN, Ohta AT, Phan HL, Hsu HY, Jamshidi A, Chiou PY, Wu MC.

Lab Chip. 2009 Oct 21;9(20):2952-7. doi: 10.1039/b907840a. Epub 2009 Jul 22.


Resolution of osteonecrosis of the jaw after teriparatide [recombinant human PTH-(1-34)] therapy.

Lau AN, Adachi JD.

J Rheumatol. 2009 Aug;36(8):1835-7. doi: 10.3899/jrheum.081176. No abstract available.


Improvement in health-related quality of life in osteoporosis patients treated with teriparatide.

Lau AN, Ali SH, Sawka AM, Thabane L, Papaioannou A, Gafni A, Adachi JD.

BMC Musculoskelet Disord. 2008 Nov 7;9:151. doi: 10.1186/1471-2474-9-151.


Horse domestication and conservation genetics of Przewalski's horse inferred from sex chromosomal and autosomal sequences.

Lau AN, Peng L, Goto H, Chemnick L, Ryder OA, Makova KD.

Mol Biol Evol. 2009 Jan;26(1):199-208. doi: 10.1093/molbev/msn239. Epub 2008 Oct 17.


Bioremediation of oil-contaminated sediments on an inter-tidal shoreline using a slow-release fertilizer and chitosan.

Xu R, Lau AN, Lim YG, Obbard JP.

Mar Pollut Bull. 2005;51(8-12):1062-70. Epub 2005 Apr 14.


Electrochemical delivery of dopamine.

Miller LL, Lau AN, Zinger B.

Neurosci Lett. 1983 Feb 21;35(2):101-4. No abstract available.


Simple sensitive technique for detecting organochlorine pesticides on thin layer chromatograms.

Ludwick AG, Lau AN, Ludwick LM.

J Assoc Off Anal Chem. 1977 Sep;60(5):1077-80.


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