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Evaluating for human herpesvirus 6 in the liver explants of children with liver failure of unknown etiology.

Yang CH, Sahoo MK, Fitzpatrick M, Lau AH, Pinsky BA, Martinez OM.

J Infect Dis. 2018 Nov 10. doi: 10.1093/infdis/jiy644. [Epub ahead of print]


A mass spectrometry-based modelling workflow for accurate prediction of IgG antibody conformations in the gas phase.

Hansen K, Lau AMC, Giles K, McDonnell JM, Struwe WB, Sutton BJ, Politis A.

Angew Chem Int Ed Engl. 2018 Nov 8. doi: 10.1002/anie.201812018. [Epub ahead of print]


Shiga Toxin/Lipopolysaccharide Activates Caspase-4 and Gasdermin D to Trigger Mitochondrial Reactive Oxygen Species Upstream of the NLRP3 Inflammasome.

Platnich JM, Chung H, Lau A, Sandall CF, Bondzi-Simpson A, Chen HM, Komada T, Trotman-Grant AC, Brandelli JR, Chun J, Beck PL, Philpott DJ, Girardin SE, Ho M, Johnson RP, MacDonald JA, Armstrong GD, Muruve DA.

Cell Rep. 2018 Nov 6;25(6):1525-1536.e7. doi: 10.1016/j.celrep.2018.09.071.


Indoor exposure to ambient particles and its estimation using fixed site monitors.

Che W, Frey HC, Li Z, Lao X, Lau AKH.

Environ Sci Technol. 2018 Nov 6. doi: 10.1021/acs.est.8b04474. [Epub ahead of print]


Long-Term Exposure to Ambient Fine Particulate Matter and Chronic Kidney Disease: A Cohort Study.

Chan TC, Zhang Z, Lin BC, Lin C, Deng HB, Chuang YC, Chan JWM, Jiang WK, Tam T, Chang LY, Hoek G, Lau AKH, Lao XQ.

Environ Health Perspect. 2018 Oct;126(10):107002. doi: 10.1289/EHP3304.


PKM2 is not required for pancreatic ductal adenocarcinoma.

Hillis AL, Lau AN, Devoe CX, Dayton TL, Danai LV, Di Vizio D, Vander Heiden MG.

Cancer Metab. 2018 Oct 23;6:17. doi: 10.1186/s40170-018-0188-1. eCollection 2018.


Exploring Cultural Differences in Expressive Suppression and Emotion Recognition.

Sun M, Lau AS.

J Cross Cult Psychol. 2018 May 1;49(4):664-672. doi: 10.1177/0022022118763749. Epub 2018 Apr 4.


pRAD50: a novel and clinically applicable pharmacodynamic biomarker of both ATM and ATR inhibition identified using mass spectrometry and immunohistochemistry.

Jones GN, Rooney C, Griffin N, Roudier M, Young LA, Garcia-Trinidad A, Hughes GD, Whiteaker JR, Wilson Z, Odedra R, Zhao L, Ivey RG, Howat WJ, Harrington EA, Barrett JC, Ramos-Montoya A, Lau A, Paulovich AG, Cadogan EB, Pierce AJ.

Br J Cancer. 2018 Nov 2. doi: 10.1038/s41416-018-0286-4. [Epub ahead of print]


Analysis of the adverse health effects of PM2.5 from 2001 to 2017 in China and the role of urbanization in aggravating the health burden.

Lu X, Lin C, Li W, Chen Y, Huang Y, Fung JCH, Lau AKH.

Sci Total Environ. 2018 Oct 18;652:683-695. doi: 10.1016/j.scitotenv.2018.10.140. [Epub ahead of print]


Analyzing Protein Architectures and Protein-Ligand Complexes by Integrative Structural Mass Spectrometry.

Ahdash Z, Lau AM, Martens C, Politis A.

J Vis Exp. 2018 Oct 15;(140). doi: 10.3791/57966.


Up-regulated expression of spherical body protein 2 truncated copy 11 in Babesia bovis is associated with reduced cytoadhesion to vascular endothelial cells.

Gallego-Lopez GM, Lau AOT, O'Connor RM, Ueti MW, Cooke BM, Laughery JM, Graça T, Madsen-Bouterse SA, Oldiges DP, Allred DR, Suarez CE.

Int J Parasitol. 2018 Oct 25. pii: S0020-7519(18)30238-8. doi: 10.1016/j.ijpara.2018.05.015. [Epub ahead of print]


Discovery and Characterization of AZD6738, a Potent Inhibitor of Ataxia Telangiectasia Mutated and Rad3 Related (ATR) Kinase with Application as an Anticancer Agent.

Foote KM, Nissink JWM, McGuire T, Turner P, Guichard S, Yates JWT, Lau A, Blades K, Heathcote D, Odedra R, Wilkinson G, Wilson Z, Wood CM, Jewsbury PJ.

J Med Chem. 2018 Nov 10. doi: 10.1021/acs.jmedchem.8b01187. [Epub ahead of print]


Evaluation of Carbazeran 4-Oxidation and O6-Benzylguanine 8-Oxidation as Catalytic Markers of Human Aldehyde Oxidase: Impact of Cytosolic Contamination of Liver Microsomes.

Xie J, Saburulla NF, Chen S, Wong SY, Yap ZP, Zhang LH, Lau AJ.

Drug Metab Dispos. 2018 Oct 18. pii: dmd.118.082099. doi: 10.1124/dmd.118.082099. [Epub ahead of print]


mHealth App Patient Testing and Review of Educational Materials Designed for Self-Management of Gout Patients: Descriptive Qualitative Studies.

Nguyen AD, Frensham LJ, Wong MX, Meslin SM, Martin P, Lau AY, Baysari MT, Day RO.

JMIR Mhealth Uhealth. 2018 Oct 15;6(10):e182. doi: 10.2196/mhealth.9811.


13C Pyruvate Transport Across the Blood-Brain Barrier in Preclinical Hyperpolarised MRI.

Miller JJ, Grist JT, Serres S, Larkin JR, Lau AZ, Ray K, Fisher KR, Hansen E, Tougaard RS, Nielsen PM, Lindhardt J, Laustsen C, Gallagher FA, Tyler DJ, Sibson N.

Sci Rep. 2018 Oct 10;8(1):15082. doi: 10.1038/s41598-018-33363-5.


Direct protein-lipid interactions shape the conformational landscape of secondary transporters.

Martens C, Shekhar M, Borysik AJ, Lau AM, Reading E, Tajkhorshid E, Booth PJ, Politis A.

Nat Commun. 2018 Oct 8;9(1):4151. doi: 10.1038/s41467-018-06704-1.


A phase 2 study of lenalidomide and dexamethasone in previously untreated patients with chronic lymphocytic leukemia (CLL).

Chen CI, Paul H, Snitzler S, Kakar S, Le LW, Wei EN, Lau A, Johnston JB, Gibson SB, Queau M, Spaner D, Croucher D, Sherry B, Trudel S.

Leuk Lymphoma. 2018 Oct 2:1-10. doi: 10.1080/10428194.2018.1508669. [Epub ahead of print]


Predictors of Burnout among Community Therapists in the Sustainment Phase of a System-Driven Implementation of Multiple Evidence-Based Practices in Children's Mental Health.

Kim JJ, Brookman-Frazee L, Gellatly R, Stadnick N, Barnett ML, Lau AS.

Prof Psychol Res Pr. 2018 Apr;49(2):131-142. doi: 10.1037/pro0000182.


Discovery of microRNA-like RNAs during early fruiting body development in the model mushroom Coprinopsis cinerea.

Lau AYT, Cheng X, Cheng CK, Nong W, Cheung MK, Chan RH, Hui JHL, Kwan HS.

PLoS One. 2018 Sep 19;13(9):e0198234. doi: 10.1371/journal.pone.0198234. eCollection 2018.


Economic evaluation of patient-centered care among long-term cancer survivors.

An J, Lau A.

Am J Manag Care. 2018 Sep 1;24(9):e292-e299.


JAK2/IDH-mutant-driven myeloproliferative neoplasm is sensitive to combined targeted inhibition.

McKenney AS, Lau AN, Somasundara AVH, Spitzer B, Intlekofer AM, Ahn J, Shank K, Rapaport FT, Patel MA, Papalexi E, Shih AH, Chiu A, Freinkman E, Akbay EA, Steadman M, Nagaraja R, Yen K, Teruya-Feldstein J, Wong KK, Rampal R, Vander Heiden MG, Thompson CB, Levine RL.

J Clin Invest. 2018 Oct 1;128(10):4743. doi: 10.1172/JCI124920. Epub 2018 Sep 17. No abstract available.


Transmitter and receiver DSP for 112 Gbit/s PAM-4 amplifier-less transmissions using 25G-class EML and APD.

Huo J, Zhou X, Zhong KP, Tu J, Yuan J, Guo C, Long K, Yu C, Lau APT, Lu C.

Opt Express. 2018 Sep 3;26(18):22673-22686. doi: 10.1364/OE.26.022673.


El Niño Altered Gut Microbiota of Children: A New Insight on Weather-Gut Interactions and Protective Effects of Probiotic.

Lau ASY, Mitsuyama E, Odamaki T, Xiao JZ, Liong MT.

J Med Food. 2018 Sep 5. doi: 10.1089/jmf.2018.4276. [Epub ahead of print]


Findings from 2017 on Consumer Health Informatics and Education: Health Data Access and Sharing.

Staccini P, Lau AYS; Section Editors for the IMIA Yearbook Section on Consumer Health Informatics and Education.

Yearb Med Inform. 2018 Aug;27(1):163-169. doi: 10.1055/s-0038-1641218. Epub 2018 Aug 29. Review.


Clinical relevance of the 21-gene Recurrence Score® assay in treatment decisions for patients with node-positive breast cancer in the genomic era.

Mamounas EP, Russell CA, Lau A, Turner MP, Albain KS.

NPJ Breast Cancer. 2018 Aug 20;4:27. doi: 10.1038/s41523-018-0082-6. eCollection 2018. Review.


Cytosolic Aspartate Availability Determines Cell Survival When Glutamine Is Limiting.

Alkan HF, Walter KE, Luengo A, Madreiter-Sokolowski CT, Stryeck S, Lau AN, Al-Zoughbi W, Lewis CA, Thomas CJ, Hoefler G, Graier WF, Madl T, Vander Heiden MG, Bogner-Strauss JG.

Cell Metab. 2018 Nov 6;28(5):706-720.e6. doi: 10.1016/j.cmet.2018.07.021. Epub 2018 Aug 16.


Metabolic signature of squamous cell carcinoma of the head and neck: Consequences of TP53 mutation and therapeutic perspectives.

Wilkie MD, Lau AS, Vlatkovic N, Jones TM, Boyd MT.

Oral Oncol. 2018 Aug;83:1-10. doi: 10.1016/j.oraloncology.2018.05.018. Epub 2018 Jun 2. Review.


Prospective Evaluation of a Practical Guideline for Managing Positive Sterility Test Results in Cell Therapy Products.

Panch SR, Bikkani T, Vargas V, Procter J, Atkins JW, Guptill V, Frank KM, Lau AF, Stroncek DF.

Biol Blood Marrow Transplant. 2018 Aug 9. pii: S1083-8791(18)30456-7. doi: 10.1016/j.bbmt.2018.08.003. [Epub ahead of print]


Tertiary lymphoid organs: A novel target in patients with chronic rhinosinusitis.

Paramasivan S, Lester S, Lau A, Ou J, Psaltis AJ, Wormald PJ, Vreugde S.

J Allergy Clin Immunol. 2018 Nov;142(5):1673-1676. doi: 10.1016/j.jaci.2018.07.024. Epub 2018 Aug 7. No abstract available.


Living Donors: Caring for the Trailblazers of Progress in Transplantation.

Lau A, Scully RE, Brännström M, Tullius SG.

Transplantation. 2018 Nov;102(11):e461. doi: 10.1097/TP.0000000000002398. No abstract available.


Visualizing Oncolytic Virus-Host Interactions in Live Mice Using Intravital Microscopy.

Naumenko V, Van S, Dastidar H, Kim DS, Kim SJ, Zeng Z, Deniset J, Lau A, Zhang C, Macia N, Heyne B, Jenne CN, Mahoney DJ.

Mol Ther Oncolytics. 2018 Jul 14;10:14-27. doi: 10.1016/j.omto.2018.06.001. eCollection 2018 Sep 28.


Conservation of oncofetal antigens on human embryonic stem cells enables discovery of monoclonal antibodies against cancer.

Tan HL, Yong C, Tan BZ, Fong WJ, Padmanabhan J, Chin A, Ding V, Lau A, Zheng L, Bi X, Yang Y, Choo A.

Sci Rep. 2018 Aug 2;8(1):11608. doi: 10.1038/s41598-018-30070-z.


Regulation of human mitogen-activated protein kinase 15 (extracellular signal-regulated kinase 7/8) and its functions: A recent update.

Lau ATY, Xu YM.

J Cell Physiol. 2018 Jan;234(1):75-88. doi: 10.1002/jcp.27053. Epub 2018 Aug 2. Review.


Evaluating the accuracy of multicomponent T2 parameters for luminal water imaging of the prostate with acceleration using inner-volume 3D GRASE.

Chan RW, Lau AZ, Detzler G, Thayalasuthan V, Nam RK, Haider MA.

Magn Reson Med. 2018 Jul 29. doi: 10.1002/mrm.27372. [Epub ahead of print]


Getting fit for hip and knee replacement: a protocol for the Fit-Joints pilot randomized controlled trial of a multi-modal intervention in frail patients with osteoarthritis.

Negm AM, Kennedy CC, Ioannidis G, Gajic-Veljanoski O, Lee J, Thabane L, Adachi JD, Marr S, Lau A, Atkinson S, Petruccelli D, DeBeer J, Winemaker M, Avram V, Deheshi B, Williams D, Armstrong D, Lumb B, Panju A, Richardson J, Papaioannou A.

Pilot Feasibility Stud. 2018 Jul 20;4:127. doi: 10.1186/s40814-018-0316-2. eCollection 2018.


High prevalence and indexes of anti-John Cunningham virus antibodies in a cohort of Chinese patients with multiple sclerosis.

Lau A, Qiu W, Kermode A, Au C, Ng A, Wong A, Ma SH, Au L, Ma K, Ip B, Mok V.

Mult Scler J Exp Transl Clin. 2018 Jul 17;4(3):2055217318788699. doi: 10.1177/2055217318788699. eCollection 2018 Jul-Sep.


Results of the UK NEQAS for Molecular Genetics reference sample analysis.

Richman SD, Fairley J, Hall JA, Nataraj N, Bhide M, Lau A, Norman KL, Deans ZC.

J Clin Pathol. 2018 Nov;71(11):989-994. doi: 10.1136/jclinpath-2018-205277. Epub 2018 Jul 20.


Qualitative Reports of How and When Therapists Adapt Children's Evidence-Based Practices during Community Implementation.

Barnett ML, Brookman-Frazee L, Gonzalez JC, Zhan C, Rodriguez A, Stadnick NA, Lau AS.

J Clin Child Adolesc Psychol. 2018 Jul 19:1-12. doi: 10.1080/15374416.2018.1485107. [Epub ahead of print]


BeSMART2: What is the Best Supportive Management for Adults Referred with Tonsillopharyngitis? Our experience surveying the attitudes of 80 patients and professionals.

Taib BG, Abbas JR, Earnshaw CH, Veitch J, Selwyn DM, Lau AS.

Clin Otolaryngol. 2018 Jul 19. doi: 10.1111/coa.13192. [Epub ahead of print] No abstract available.


Germline-activating mutations in PIK3CD compromise B cell development and function.

Avery DT, Kane A, Nguyen T, Lau A, Nguyen A, Lenthall H, Payne K, Shi W, Brigden H, French E, Bier J, Hermes JR, Zahra D, Sewell WA, Butt D, Elliott M, Boztug K, Meyts I, Choo S, Hsu P, Wong M, Berglund LJ, Gray P, O'Sullivan M, Cole T, Holland SM, Ma CS, Burkhart C, Corcoran LM, Phan TG, Brink R, Uzel G, Deenick EK, Tangye SG.

J Exp Med. 2018 Aug 6;215(8):2073-2095. doi: 10.1084/jem.20180010. Epub 2018 Jul 17.


Conversational agents in healthcare: a systematic review.

Laranjo L, Dunn AG, Tong HL, Kocaballi AB, Chen J, Bashir R, Surian D, Gallego B, Magrabi F, Lau AYS, Coiera E.

J Am Med Inform Assoc. 2018 Sep 1;25(9):1248-1258. doi: 10.1093/jamia/ocy072.


Ultracentral Tumors Treated With Stereotactic Body Radiotherapy: Single-Institution Experience.

Raman S, Yau V, Pineda S, Le LW, Lau A, Bezjak A, Cho BCJ, Sun A, Hope AJ, Giuliani M.

Clin Lung Cancer. 2018 Sep;19(5):e803-e810. doi: 10.1016/j.cllc.2018.06.001. Epub 2018 Jun 18.


Standard Method Performance Requirements (SMPRs®) 2018.003: Quantitation of Milk by ELISA-Based Methods.

Godefroy S, Yeung J, Albornoz G, Almy D, Green AB, Bhandari S, Brown R, Da Costa P, Digonnet V, Doi H, Dubois A, Garber E, Geng T, Gilboa-Geffen A, Goodwin P, Haas-Lauterbach S, Indyk H, Kavolis D, Koerner T, Lacorn M, Lau A, Nishiyama Y, OConnor G, Poms R, Popping B, Rallabhandi P, Ryan M, Sharma G, Shoji M, Swoboda C, Tomiki M, Wallace A, Yang C, Yang J.

J AOAC Int. 2018 Jul 1;101(4):1276-1278. doi: 10.5740/jaoacint.SMPR2018.003. No abstract available.


Standard Method Performance Requirements (SMPRs®) 2017.020: Quantitation of Chicken Egg by ELISA-Based Methods.

Godefroy S, Yeung J, Albornoz G, Almy D, Green AB, Bhandari S, Brown R, Da Costa P, Digonnet V, Doi H, Garber E, Geng T, Gilboa-Geffen A, Goodwin P, Haas-Lauterbach S, Kavolis D, Koerner T, Lacorn M, Lau A, Nishiyama Y, O'Connor G, Poms R, Popping B, Rallabhandi P, Ryan M, Sharma G, Shoji M, Swoboda C, Tomiki M, Wallace A, Yang C, Yang J.

J AOAC Int. 2018 Jul 1;101(4):1236-1237. doi: 10.5740/jaoacint.SMPR2017.020. No abstract available.


Correction to Discovery of Novel 3-Quinoline Carboxamides as Potent, Selective, and Orally Bioavailable Inhibitors of Ataxia Telangiectasia Mutated (ATM) Kinase.

Degorce SL, Barlaam B, Cadogan E, Dishington A, Ducray R, Glossop SC, Hassall LA, Lach F, Lau A, McGuire TM, Nowak T, Ouvry G, Pike KG, Thomason AG.

J Med Chem. 2018 Jul 3. doi: 10.1021/acs.jmedchem.8b00936. [Epub ahead of print] No abstract available.


Ethnic minority community therapists' acculturation and reported adaptations to children's evidence-based practices.

Saifan D, Brookman-Frazee L, Barnett M, Gonzalez JC, Lau AS.

Cultur Divers Ethnic Minor Psychol. 2018 Oct;24(4):530-540. doi: 10.1037/cdp0000203. Epub 2018 Jul 2.


Quantification of Inflammasome Adaptor Protein ASC in Biological Samples by Multiple-Reaction Monitoring Mass Spectrometry.

Ulke-Lemée A, Lau A, Nelson MC, James MT, Muruve DA, MacDonald JA.

Inflammation. 2018 Aug;41(4):1396-1408. doi: 10.1007/s10753-018-0787-6.


Aspartate is an endogenous metabolic limitation for tumour growth.

Sullivan LB, Luengo A, Danai LV, Bush LN, Diehl FF, Hosios AM, Lau AN, Elmiligy S, Malstrom S, Lewis CA, Vander Heiden MG.

Nat Cell Biol. 2018 Jul;20(7):782-788. doi: 10.1038/s41556-018-0125-0. Epub 2018 Jun 25.


Comparison of scrotal antegrade sclerotherapy and laparoscopic Palomo surgery in treatment of adolescent varicocele: A 15-year review.

Hung JWS, Yam FSD, Chung KLY, Lau AKW, Leung YCL, Liu CCW, Tang PMY, Chao NSY, Leung MWY, Liu KKW.

J Pediatr Urol. 2018 May 31. pii: S1477-5131(18)30219-5. doi: 10.1016/j.jpurol.2018.04.027. [Epub ahead of print]


Association of wheeze during the first 18 months of life with indoor nitrogen dioxide, formaldehyde, and family history of asthma: a prospective cohort study.

Yu IT, Li AM, Goggins W, Leung JO, Chan GY, Fung CK, Chan CK, Lau AP.

Hong Kong Med J. 2017 Jun;23 Suppl 2(3):19-23. No abstract available.

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