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A novel framework for decomposing PM2.5 variation and demographic change effects on human exposure using satellite observations.

Lin C, Lau AKH, Lao XQ, Fung JCH, Lu X, Li Z, Ma J, Li C, Wong AHS.

Environ Res. 2020 Jan 7;182:109120. doi: 10.1016/j.envres.2020.109120. [Epub ahead of print]


Lysosomal Dysregulation in the Murine AppNL-G-F/NL-G-F Model of Alzheimer's Disease.

Whyte LS, Hassiotis S, Hattersley KJ, Hemsley KM, Hopwood JJ, Lau AA, Sargeant TJ.

Neuroscience. 2020 Jan 7. pii: S0306-4522(19)30897-8. doi: 10.1016/j.neuroscience.2019.12.042. [Epub ahead of print]


AAVrh10 Vector Corrects Disease Pathology in MPS IIIA Mice and Achieves Widespread Distribution of SGSH in Large Animal Brains.

Hocquemiller M, Hemsley KM, Douglass ML, Tamang SJ, Neumann D, King BM, Beard H, Trim PJ, Winner LK, Lau AA, Snel MF, Gomila C, Ausseil J, Mei X, Giersch L, Plavsic M, Laufer R.

Mol Ther Methods Clin Dev. 2019 Dec 10;17:174-187. doi: 10.1016/j.omtm.2019.12.001. eCollection 2020 Jun 12.


Comparison of the clinical effectiveness and safety between the use of denosumab vs bisphosphonates in renal transplant patients.

McKee H, Ioannidis G, Lau A, Treleaven D, Gangji A, Ribic C, Pack MW, Papaioannou A, Adachi JD.

Osteoporos Int. 2020 Jan 3. doi: 10.1007/s00198-019-05267-1. [Epub ahead of print]


Production of tetra-methylpyrazine using engineered Corynebacterium glutamicum.

Eng T, Sasaki Y, Herbert RA, Lau A, Trinh J, Chen Y, Mirsiaghi M, Petzold CJ, Mukhopadhyay A.

Metab Eng Commun. 2019 Dec 2;10:e00115. doi: 10.1016/j.mec.2019.e00115. eCollection 2020 Jun.


Quantitative MRI Biomarkers of Stereotactic Radiotherapy Outcome in Brain Metastasis.

Karami E, Soliman H, Ruschin M, Sahgal A, Myrehaug S, Tseng CL, Czarnota GJ, Jabehdar-Maralani P, Chugh B, Lau A, Stanisz GJ, Sadeghi-Naini A.

Sci Rep. 2019 Dec 27;9(1):19830. doi: 10.1038/s41598-019-56185-5.


Developing and introducing a post birth care plan (PBCP): An action research project.

Crowther S, Lau A, MacIver E.

Midwifery. 2019 Dec 16;82:102616. doi: 10.1016/j.midw.2019.102616. [Epub ahead of print]


Chromatic dispersion mitigation using a SEFDM-based diversity technique for IM/DD long reach optical links.

Yu B, Guo C, Zhang S, Zuo T, Liu L, Lau APT, Lu C, Zhang H.

Opt Express. 2019 Dec 23;27(26):38579-38592. doi: 10.1364/OE.381267.


Long-Term Exposure to Ambient Fine Particulate Matter (PM2.5) and Lung Function in Children, Adolescents, and Young Adults: A Longitudinal Cohort Study.

Guo C, Hoek G, Chang LY, Bo Y, Lin C, Huang B, Chan TC, Tam T, Lau AKH, Lao XQ.

Environ Health Perspect. 2019 Dec;127(12):127008. doi: 10.1289/EHP5220. Epub 2019 Dec 24.


Read-SpaM: assembly-free and alignment-free comparison of bacterial genomes with low sequencing coverage.

Lau AK, Dörrer S, Leimeister CA, Bleidorn C, Morgenstern B.

BMC Bioinformatics. 2019 Dec 17;20(Suppl 20):638. doi: 10.1186/s12859-019-3205-7.


Activated PI3Kδ breaches multiple B cell tolerance checkpoints and causes autoantibody production.

Lau A, Avery DT, Jackson K, Lenthall H, Volpi S, Brigden H, Russell AJ, Bier J, Reed JH, Smart JM, Cole T, Choo S, Gray PE, Berglund LJ, Hsu P, Wong M, O'Sullivan M, Boztug K, Meyts I, Uzel G, Notarangelo LD, Brink R, Goodnow CC, Tangye SG, Deenick EK.

J Exp Med. 2020 Feb 3;217(2). pii: e20191336. doi: 10.1084/jem.20191336.


Selection in the germinal center.

Lau AW, Brink R.

Curr Opin Immunol. 2019 Dec 10;63:29-34. doi: 10.1016/j.coi.2019.11.001. [Epub ahead of print] Review.


Caregiver Attendance as a Quality Indicator in the Implementation of Multiple Evidence-Based Practices for Children.

Barnett ML, Lau AS, Lind T, Wright B, Stadnick NA, Innes-Gomberg D, Pesanti K, Brookman-Frazee L.

J Clin Child Adolesc Psychol. 2019 Dec 4:1-15. doi: 10.1080/15374416.2019.1683851. [Epub ahead of print]


α-Synuclein strains target distinct brain regions and cell types.

Lau A, So RWL, Lau HHC, Sang JC, Ruiz-Riquelme A, Fleck SC, Stuart E, Menon S, Visanji NP, Meisl G, Faidi R, Marano MM, Schmitt-Ulms C, Wang Z, Fraser PE, Tandon A, Hyman BT, Wille H, Ingelsson M, Klenerman D, Watts JC.

Nat Neurosci. 2020 Jan;23(1):21-31. doi: 10.1038/s41593-019-0541-x. Epub 2019 Dec 2.


Study of Hybrid Nanoparticles Modified Epoxy Resin Used in Filament Winding Composite.

Di C, Yu J, Wang B, Lau AKT, Zhu B, Qiao K.

Materials (Basel). 2019 Nov 22;12(23). pii: E3853. doi: 10.3390/ma12233853.


Phytofabrication of Nanoparticles as Novel Drugs for Anticancer Applications.

Wei QY, He KM, Chen JL, Xu YM, Lau ATY.

Molecules. 2019 Nov 21;24(23). pii: E4246. doi: 10.3390/molecules24234246. Review.


Topological Phases without Crystalline Counterparts.

Varjas D, Lau A, Pöyhönen K, Akhmerov AR, Pikulin DI, Fulga IC.

Phys Rev Lett. 2019 Nov 8;123(19):196401. doi: 10.1103/PhysRevLett.123.196401.


Pneumocystis pneumonia in a patient treated with alemtuzumab for relapsing multiple sclerosis.

Lau AY, Lui GCY, Chan KP, Au C, Mok VCT, Ziemssen T.

Mult Scler Relat Disord. 2019 Nov 6;38:101503. doi: 10.1016/j.msard.2019.101503. [Epub ahead of print]


Disrupting coupling within mycobacterial F-ATP synthases subunit ε causes dysregulated energy production and cell wall biosynthesis.

Saw WG, Wu ML, Ragunathan P, Biuković G, Lau AM, Shin J, Harikishore A, Cheung CY, Hards K, Sarathy JP, Bates RW, Cook GM, Dick T, Grüber G.

Sci Rep. 2019 Nov 14;9(1):16759. doi: 10.1038/s41598-019-53107-3.


When Do Therapists Stop Using Evidence-Based Practices? Findings from a Mixed Method Study on System-Driven Implementation of Multiple EBPs for Children.

Lau AS, Lind T, Crawley M, Rodriguez A, Smith A, Brookman-Frazee L.

Adm Policy Ment Health. 2019 Nov 12. doi: 10.1007/s10488-019-00987-2. [Epub ahead of print]


Peak width of skeletonized mean diffusivity and its association with age-related cognitive alterations and vascular risk factors.

Lam BYK, Leung KT, Yiu B, Zhao L, Biesbroek JM, Au L, Tang Y, Wang K, Fan Y, Fu JH, Xu Q, Song H, Tian X, Chu WCW, Abrigo J, Shi L, Ko H, Lau A, Duering M, Wong A, Mok VCT.

Alzheimers Dement (Amst). 2019 Oct 25;11:721-729. doi: 10.1016/j.dadm.2019.09.003. eCollection 2019 Dec.


Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels.

Xiao S, McKeever PM, Lau A, Robertson J.

Acta Neuropathol Commun. 2019 Oct 24;7(1):161. doi: 10.1186/s40478-019-0812-5.


Tracking genome-editing and associated molecular perturbations by SWATH mass spectrometry.

Lin Q, Low LWL, Lau A, Chua EWL, Matsuoka Y, Lian Y, Monteiro A, Tate S, Gunaratne J, Carney TJ.

Sci Rep. 2019 Oct 23;9(1):15240. doi: 10.1038/s41598-019-51612-z.


Can transcranial Doppler ultrasound be used for screening cerebral small vessel diseases in the community?

Kang D, Wong A, Fu J, Qun X, Liu W, Wang Z, Lin S, Kwan P, Lo E, Au LWC, Ko H, Lau AYL, Leung TWH, Abrigo J, Chu WCW, Mok VCT, Lam BYK.

J Neurol Sci. 2019 Nov 15;406:116439. doi: 10.1016/j.jns.2019.116439. Epub 2019 Aug 29.


Incorporating adjustments for variability in control group response rates in network meta-analysis: a case study of biologics for rheumatoid arthritis.

Cameron C, Varu A, Lau A, Gharaibeh M, Paulino M, Rogoza R.

BMC Med Res Methodol. 2019 Oct 16;19(1):193. doi: 10.1186/s12874-019-0837-2.


Multicenter Study Demonstrates Standardization Requirements for Mold Identification by MALDI-TOF MS.

Lau AF, Walchak RC, Miller HB, Slechta ES, Kamboj K, Riebe K, Robertson AE, Gilbreath JJ, Mitchell KF, Wallace MA, Bryson AL, Balada-Llasat JM, Bulman A, Buchan BW, Burnham CD, Butler-Wu S, Desai U, Doern CD, Hanson KE, Henderson CM, Kostrzewa M, Ledeboer NA, Maier T, Pancholi P, Schuetz AN, Shi G, Wengenack NL, Zhang SX, Zelazny AM, Frank KM.

Front Microbiol. 2019 Sep 20;10:2098. doi: 10.3389/fmicb.2019.02098. eCollection 2019.


Integrating hydrogen-deuterium exchange mass spectrometry with molecular dynamics simulations to probe lipid-modulated conformational changes in membrane proteins.

Martens C, Shekhar M, Lau AM, Tajkhorshid E, Politis A.

Nat Protoc. 2019 Nov;14(11):3183-3204. doi: 10.1038/s41596-019-0219-6. Epub 2019 Oct 11.


Plasmid Dissemination and Selection of a Multidrug-Resistant Klebsiella pneumoniae Strain during Transplant-Associated Antibiotic Therapy.

Conlan S, Lau AF, Deming C, Spalding CD, Lee-Lin S, Thomas PJ, Park M, Dekker JP, Frank KM, Palmore TN, Segre JA.

mBio. 2019 Oct 8;10(5). pii: e00652-19. doi: 10.1128/mBio.00652-19.


Comparison of a commercial spectral-domain OCT and swept-source OCT based on an angiography scan for measuring circumpapillary retinal nerve fibre layer thickness.

Tan B, Chua J, Harish T, Lau A, Gan ATL, Tan YL, Wong DWK, Chong RS, Ang M, Husain R, Schmetterer L.

Br J Ophthalmol. 2019 Oct 4. pii: bjophthalmol-2019-314706. doi: 10.1136/bjophthalmol-2019-314706. [Epub ahead of print]


A Mouse Model for Skeletal Structure and Function Changes Caused by Radiation Therapy and Estrogen Deficiency.

Sullivan LK, Livingston EW, Lau AG, Rao-Dayton S, Bateman TA.

Calcif Tissue Int. 2019 Oct 3. doi: 10.1007/s00223-019-00617-x. [Epub ahead of print]


Waste-derived compost and biochar amendments for stormwater treatment in bioretention column: Co-transport of metals and colloids.

Sun Y, Chen SS, Lau AYT, Tsang DCW, Mohanty SK, Bhatnagar A, Rinklebe J, Lin KA, Ok YS.

J Hazard Mater. 2020 Feb 5;383:121243. doi: 10.1016/j.jhazmat.2019.121243. Epub 2019 Sep 16.


A feasible experimental framework for field calibration of portable light-scattering aerosol monitors: Case of TSI DustTrak.

Li Z, Che W, Lau AKH, Fung JCH, Lin C, Lu X.

Environ Pollut. 2019 Dec;255(Pt 1):113136. doi: 10.1016/j.envpol.2019.113136. Epub 2019 Sep 5.


Crystal structure of zinc-α2-glycoprotein in complex with a fatty acid reveals multiple different modes of protein-lipid binding.

Lau AM, Zahid H, Gor J, Perkins SJ, Coker AR, McDermott LC.

Biochem J. 2019 Oct 15;476(19):2815-2834. doi: 10.1042/BCJ20190354.


Deoxycytidine Release from Pancreatic Stellate Cells Promotes Gemcitabine Resistance.

Dalin S, Sullivan MR, Lau AN, Grauman-Boss B, Mueller HS, Kreidl E, Fenoglio S, Luengo A, Lees JA, Vander Heiden MG, Lauffenburger DA, Hemann MT.

Cancer Res. 2019 Nov 15;79(22):5723-5733. doi: 10.1158/0008-5472.CAN-19-0960. Epub 2019 Sep 4.


Longitudinal Relations between Emotion Restraint Values, Life Stress, and Internalizing Symptoms among Vietnamese American and European American Adolescents.

Tsai W, Weiss B, Kim JHJ, Lau AS.

J Clin Child Adolesc Psychol. 2019 Aug 29:1-13. doi: 10.1080/15374416.2019.1650364. [Epub ahead of print]


Long-term soft tissue outcomes for hydroxyapatite-coated bone-anchored hearing implant surgery.

Kanzara T, Walijee H, Badar Sheikh R, Lau A, Temple R.

Eur Arch Otorhinolaryngol. 2019 Nov;276(11):3067-3072. doi: 10.1007/s00405-019-05609-z. Epub 2019 Aug 26.


Structural basis of Cullin 2 RING E3 ligase regulation by the COP9 signalosome.

Faull SV, Lau AMC, Martens C, Ahdash Z, Hansen K, Yebenes H, Schmidt C, Beuron F, Cronin NB, Morris EP, Politis A.

Nat Commun. 2019 Aug 23;10(1):3814. doi: 10.1038/s41467-019-11772-y.


Cultural variation in temporal associations among somatic complaints, anxiety, and depressive symptoms in adolescence.

Kim JHJ, Tsai W, Kodish T, Trung LT, Lau AS, Weiss B.

J Psychosom Res. 2019 Sep;124:109763. doi: 10.1016/j.jpsychores.2019.109763. Epub 2019 Jul 5.


Dipeptidase-1 Is an Adhesion Receptor for Neutrophil Recruitment in Lungs and Liver.

Choudhury SR, Babes L, Rahn JJ, Ahn BY, Goring KR, King JC, Lau A, Petri B, Hao X, Chojnacki AK, Thanabalasuriar A, McAvoy EF, Tabariès S, Schraeder C, Patel KD, Siegel PM, Kopciuk KA, Schriemer DC, Muruve DA, Kelly MM, Yipp BG, Kubes P, Robbins SM, Senger DL.

Cell. 2019 Aug 22;178(5):1205-1221.e17. doi: 10.1016/j.cell.2019.07.017.


Artificial Intelligence in Health: New Opportunities, Challenges, and Practical Implications.

Lau AYS, Staccini P; Section Editors for the IMIA Yearbook Section on Education and Consumer Health Informatics.

Yearb Med Inform. 2019 Aug;28(1):174-178. doi: 10.1055/s-0039-1677935. Epub 2019 Aug 16. Review.


Neutralising antibodies to interferon-beta therapy in relapsing multiple sclerosis: a pilot study.

Lau AYL, Chan E, Lau KK, Mok V, Siu DYW, Lee R.

Hong Kong Med J. 2019 Aug;25 Suppl 5(4):22-25. No abstract available.


Effects of collateral circulation on haemodynamic flow status in intracranial artery stenosis depicted by computational fluid dynamics.

Leung TWH, Fan SY, Ip HL, Lau AYL, Siu DYW, Dai EYL, Wong LKS, Liebeskind DS.

Hong Kong Med J. 2019 Aug;25 Suppl 5(4):18-21. No abstract available.


Determining known-group validity and test-retest reliability in the PEQ (personalized exercise questionnaire).

Rodrigues IB, Adachi JD, Beattie KA, Lau A, MacDermid JC.

BMC Musculoskelet Disord. 2019 Aug 14;20(1):373. doi: 10.1186/s12891-019-2761-3.


Effects of Preference on Outcomes of Preventive Interventions among Ethnically Diverse Adolescents At-Risk of Depression.

Lau AS, Kim JJ, Nguyen DJ, Nguyen HT, Kodish T, Weiss B.

J Clin Child Adolesc Psychol. 2019 Aug 13:1-17. doi: 10.1080/15374416.2019.1639514. [Epub ahead of print]


Physical activities attenuate the negative cognitive impact from white matter hyperintensities in stroke and TIA patients with low education.

Wong A, Yiu S, Lam BYK, Leung KT, Shi L, Lo E, Abrigo J, Au LW, Lau A, Mok V.

Int J Geriatr Psychiatry. 2019 Dec;34(12):1792-1798. doi: 10.1002/gps.5194. Epub 2019 Aug 27.


Lasting DNA Damage and Aberrant DNA Repair Gene Expression Profile Are Associated with Post-Chronic Cadmium Exposure in Human Bronchial Epithelial Cells.

Tan HW, Liang ZL, Yao Y, Wu DD, Mo HY, Gu J, Chiu JF, Xu YM, Lau ATY.

Cells. 2019 Aug 6;8(8). pii: E842. doi: 10.3390/cells8080842.


Barriers and Facilitators to Cochlear Implant Uptake in Australia and the United Kingdom.

Bierbaum M, McMahon CM, Hughes S, Boisvert I, Lau AYS, Braithwaite J, Rapport F.

Ear Hear. 2019 Jul 24. doi: 10.1097/AUD.0000000000000762. [Epub ahead of print]


Benchmarking of alignment-free sequence comparison methods.

Zielezinski A, Girgis HZ, Bernard G, Leimeister CA, Tang K, Dencker T, Lau AK, Röhling S, Choi JJ, Waterman MS, Comin M, Kim SH, Vinga S, Almeida JS, Chan CX, James BT, Sun F, Morgenstern B, Karlowski WM.

Genome Biol. 2019 Jul 25;20(1):144. doi: 10.1186/s13059-019-1755-7.


Increased PHGDH expression promotes aberrant melanin accumulation.

Mattaini KR, Sullivan MR, Lau AN, Fiske BP, Bronson RT, Vander Heiden MG.

BMC Cancer. 2019 Jul 22;19(1):723. doi: 10.1186/s12885-019-5933-5.


Structures of SCCmec elements in methicillin-resistant Staphylococcus lugdunensis are closely related to those harboured by community-associated methicillin-resistant Staphylococcus aureus.

Liu MC, Cao H, Lau A, Chow KH, Lai EL, Tse CW, Wu AK, Ho PL.

J Med Microbiol. 2019 Sep;68(9):1367-1372. doi: 10.1099/jmm.0.001013.


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