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Items: 1 to 50 of 616

1.

Communication of CD8+ T cells with mononuclear phagocytes in multiple sclerosis.

Konjevic Sabolek M, Held K, Beltrán E, Niedl AG, Meinl E, Hohlfeld R, Lassmann H, Dornmair K.

Ann Clin Transl Neurol. 2019 Jul;6(7):1151-1164. doi: 10.1002/acn3.783. Epub 2019 Jun 14.

2.

PDE10A antibodies in autoimmune encephalitis: A possible marker of cancer immunotherapy?

Titulaer MJ, Irani SR, Lassmann H.

Neurology. 2019 Jul 17. pii: 10.1212/WNL.0000000000007965. doi: 10.1212/WNL.0000000000007965. [Epub ahead of print] No abstract available.

PMID:
31315974
3.

PECAM-1 Stabilizes Blood-Brain Barrier Integrity and Favors Paracellular T-Cell Diapedesis Across the Blood-Brain Barrier During Neuroinflammation.

Wimmer I, Tietz S, Nishihara H, Deutsch U, Sallusto F, Gosselet F, Lyck R, Muller WA, Lassmann H, Engelhardt B.

Front Immunol. 2019 Apr 5;10:711. doi: 10.3389/fimmu.2019.00711. eCollection 2019.

4.

The changing concepts in the neuropathology of acquired demyelinating central nervous system disorders.

Lassmann H.

Curr Opin Neurol. 2019 Jun;32(3):313-319. doi: 10.1097/WCO.0000000000000685.

PMID:
30893100
5.

Microglia pre-activation and neurodegeneration precipitate neuroinflammation without exacerbating tissue injury in experimental autoimmune encephalomyelitis.

Wimmer I, Scharler C, Zrzavy T, Kadowaki T, Mödlagl V, Rojc K, Tröscher AR, Kitic M, Ueda S, Bradl M, Lassmann H.

Acta Neuropathol Commun. 2019 Jan 31;7(1):14. doi: 10.1186/s40478-019-0667-9.

6.

Pathogenic Mechanisms Associated With Different Clinical Courses of Multiple Sclerosis.

Lassmann H.

Front Immunol. 2019 Jan 10;9:3116. doi: 10.3389/fimmu.2018.03116. eCollection 2018. Review.

7.

Microglial nodules provide the environment for pathogenic T cells in human encephalitis.

Tröscher AR, Wimmer I, Quemada-Garrido L, Köck U, Gessl D, Verberk SGS, Martin B, Lassmann H, Bien CG, Bauer J.

Acta Neuropathol. 2019 Apr;137(4):619-635. doi: 10.1007/s00401-019-01958-5. Epub 2019 Jan 20.

8.

A proliferation-inducing ligand-mediated anti-inflammatory response of astrocytes in multiple sclerosis.

Baert L, Benkhoucha M, Popa N, Ahmed MC, Manfroi B, Boutonnat J, Sturm N, Raguenez G, Tessier M, Casez O, Marignier R, Ahmadi M, Broisat A, Ghezzi C, Rivat C, Sonrier C, Hahne M, Baeten D, Vives RR, Lortat-Jacob H, Marche PN, Schneider P, Lassmann HP, Boucraut J, Lalive PH, Huard B.

Ann Neurol. 2019 Mar;85(3):406-420. doi: 10.1002/ana.25415. Epub 2019 Feb 4.

PMID:
30635946
9.

Circulating AQP4-specific auto-antibodies alone can induce neuromyelitis optica spectrum disorder in the rat.

Hillebrand S, Schanda K, Nigritinou M, Tsymala I, Böhm D, Peschl P, Takai Y, Fujihara K, Nakashima I, Misu T, Reindl M, Lassmann H, Bradl M.

Acta Neuropathol. 2019 Mar;137(3):467-485. doi: 10.1007/s00401-018-1950-8. Epub 2018 Dec 18.

10.

TPP2 mutation associated with sterile brain inflammation mimicking MS.

Reinthaler EM, Graf E, Zrzavy T, Wieland T, Hotzy C, Kopecky C, Pferschy S, Schmied C, Leutmezer F, Keilani M, Lill CM, Hoffjan S, Epplen JT, Zettl UK, Hecker M, Deutschländer A, Meuth SG, Ahram M, Mustafa B, El-Khateeb M, Vilariño-Güell C, Sadovnick AD, Zimprich F, Tomkinson B, Strom T, Kristoferitsch W, Lassmann H, Zimprich A.

Neurol Genet. 2018 Nov 13;4(6):e285. doi: 10.1212/NXG.0000000000000285. eCollection 2018 Dec.

11.

7 T Magnetic Resonance Spectroscopic Imaging in Multiple Sclerosis: How Does Spatial Resolution Affect the Detectability of Metabolic Changes in Brain Lesions?

Heckova E, Strasser B, Hangel GJ, Považan M, Dal-Bianco A, Rommer PS, Bednarik P, Gruber S, Leutmezer F, Lassmann H, Trattnig S, Bogner W.

Invest Radiol. 2019 Apr;54(4):247-254. doi: 10.1097/RLI.0000000000000531.

PMID:
30433892
12.

Microvessels may Confound the "Swallow Tail Sign" in Normal Aged Midbrains: A Postmortem 7 T SW-MRI Study.

Kau T, Hametner S, Endmayr V, Deistung A, Prihoda M, Haimburger E, Menard C, Haider T, Höftberger R, Robinson S, Reichenbach JR, Lassmann H, Traxler H, Trattnig S, Grabner G.

J Neuroimaging. 2019 Jan;29(1):65-69. doi: 10.1111/jon.12576. Epub 2018 Nov 8.

PMID:
30407679
13.

Acute microglia ablation induces neurodegeneration in the somatosensory system.

Rubino SJ, Mayo L, Wimmer I, Siedler V, Brunner F, Hametner S, Madi A, Lanser A, Moreira T, Donnelly D, Cox L, Rezende RM, Butovsky O, Lassmann H, Weiner HL.

Nat Commun. 2018 Nov 1;9(1):4578. doi: 10.1038/s41467-018-05929-4.

14.

Multiple Sclerosis Pathology and its Reflection by Imaging Technologies: Introduction.

Lassmann H.

Brain Pathol. 2018 Sep;28(5):721-722. doi: 10.1111/bpa.12649. No abstract available.

PMID:
30375112
15.

Neuroinflammatory responses in experimental and human stroke lesions.

Wimmer I, Zrzavy T, Lassmann H.

J Neuroimmunol. 2018 Oct 15;323:10-18. doi: 10.1016/j.jneuroim.2018.07.003. Epub 2018 Jul 6. Review.

16.

Orthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes.

Martin NA, Nawrocki A, Molnar V, Elkjaer ML, Thygesen EK, Palkovits M, Acs P, Sejbaek T, Nielsen HH, Hegedus Z, Sellebjerg F, Molnar T, Barbosa EGV, Alcaraz N, Gallyas F Jr, Svenningsen AF, Baumbach J, Lassmann H, Larsen MR, Illes Z.

PLoS One. 2018 Aug 16;13(8):e0202530. doi: 10.1371/journal.pone.0202530. eCollection 2018.

17.

Iron related changes in MS lesions and their validity to characterize MS lesion types and dynamics with Ultra-high field magnetic resonance imaging.

Hametner S, Dal Bianco A, Trattnig S, Lassmann H.

Brain Pathol. 2018 Sep;28(5):743-749. doi: 10.1111/bpa.12643. Review.

PMID:
30020556
18.

Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein.

Spadaro M, Winklmeier S, Beltrán E, Macrini C, Höftberger R, Schuh E, Thaler FS, Gerdes LA, Laurent S, Gerhards R, Brändle S, Dornmair K, Breithaupt C, Krumbholz M, Moser M, Krishnamoorthy G, Kamp F, Jenne D, Hohlfeld R, Kümpfel T, Lassmann H, Kawakami N, Meinl E.

Ann Neurol. 2018 Aug;84(2):315-328. doi: 10.1002/ana.25291. Epub 2018 Sep 9.

PMID:
30014603
19.

The influence of brain iron and myelin on magnetic susceptibility and effective transverse relaxation - A biochemical and histological validation study.

Hametner S, Endmayr V, Deistung A, Palmrich P, Prihoda M, Haimburger E, Menard C, Feng X, Haider T, Leisser M, Köck U, Kaider A, Höftberger R, Robinson S, Reichenbach JR, Lassmann H, Traxler H, Trattnig S, Grabner G.

Neuroimage. 2018 Oct 1;179:117-133. doi: 10.1016/j.neuroimage.2018.06.007. Epub 2018 Jun 15.

PMID:
29890327
20.

The compartmentalized inflammatory response in the multiple sclerosis brain is composed of tissue-resident CD8+ T lymphocytes and B cells.

Machado-Santos J, Saji E, Tröscher AR, Paunovic M, Liblau R, Gabriely G, Bien CG, Bauer J, Lassmann H.

Brain. 2018 Jul 1;141(7):2066-2082. doi: 10.1093/brain/awy151.

21.

Impaired plasticity of macrophages in X-linked adrenoleukodystrophy.

Weinhofer I, Zierfuss B, Hametner S, Wagner M, Popitsch N, Machacek C, Bartolini B, Zlabinger G, Ohradanova-Repic A, Stockinger H, Köhler W, Höftberger R, Regelsberger G, Forss-Petter S, Lassmann H, Berger J.

Brain. 2018 Aug 1;141(8):2329-2342. doi: 10.1093/brain/awy127.

22.

Pro-inflammatory activation of microglia in the brain of patients with sepsis.

Zrzavy T, Höftberger R, Berger T, Rauschka H, Butovsky O, Weiner H, Lassmann H.

Neuropathol Appl Neurobiol. 2019 Apr;45(3):278-290. doi: 10.1111/nan.12502. Epub 2018 Jun 19.

23.

Omics-Based Approach Reveals Complement-Mediated Inflammation in Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS).

Blaabjerg M, Hemdrup AL, Drici L, Ruprecht K, Garred P, Höftberger R, Kristensen BW, Kondziella D, Sejbaek T, Hansen SW, Nielsen HH, Jensen P, Meyer M, Paul F, Lassmann H, Larsen MR, Illes Z.

Front Immunol. 2018 Apr 23;9:741. doi: 10.3389/fimmu.2018.00741. eCollection 2018.

24.

Systematic evaluation of RNA quality, microarray data reliability and pathway analysis in fresh, fresh frozen and formalin-fixed paraffin-embedded tissue samples.

Wimmer I, Tröscher AR, Brunner F, Rubino SJ, Bien CG, Weiner HL, Lassmann H, Bauer J.

Sci Rep. 2018 Apr 20;8(1):6351. doi: 10.1038/s41598-018-24781-6.

25.

Selective Inversion Recovery Quantitative Magnetization Transfer Brain MRI at 7T: Clinical and Postmortem Validation in Multiple Sclerosis.

Bagnato F, Hametner S, Franco G, Pawate S, Sriram S, Lassmann H, Gore J, Smith SE, Dortch R.

J Neuroimaging. 2018 Jul;28(4):380-388. doi: 10.1111/jon.12511. Epub 2018 Apr 19.

26.

Experimental Demyelination and Axonal Loss Are Reduced in MicroRNA-146a Deficient Mice.

Martin NA, Molnar V, Szilagyi GT, Elkjaer ML, Nawrocki A, Okarmus J, Wlodarczyk A, Thygesen EK, Palkovits M, Gallyas F Jr, Larsen MR, Lassmann H, Benedikz E, Owens T, Svenningsen AF, Illes Z.

Front Immunol. 2018 Mar 12;9:490. doi: 10.3389/fimmu.2018.00490. eCollection 2018.

27.

Untangling the R2* contrast in multiple sclerosis: A combined MRI-histology study at 7.0 Tesla.

Bagnato F, Hametner S, Boyd E, Endmayr V, Shi Y, Ikonomidou V, Chen G, Pawate S, Lassmann H, Smith S, Welch EB.

PLoS One. 2018 Mar 21;13(3):e0193839. doi: 10.1371/journal.pone.0193839. eCollection 2018.

28.

Mechanisms for lesion localization in neuromyelitis optica spectrum disorders.

Bradl M, Reindl M, Lassmann H.

Curr Opin Neurol. 2018 Jun;31(3):325-333. doi: 10.1097/WCO.0000000000000551. Review.

29.

Microglial Phenotypes and Functions in Multiple Sclerosis.

O'Loughlin E, Madore C, Lassmann H, Butovsky O.

Cold Spring Harb Perspect Med. 2018 Feb 1;8(2). pii: a028993. doi: 10.1101/cshperspect.a028993. Review.

PMID:
29419406
30.

Multiple Sclerosis Pathology.

Lassmann H.

Cold Spring Harb Perspect Med. 2018 Mar 1;8(3). pii: a028936. doi: 10.1101/cshperspect.a028936. Review.

PMID:
29358320
31.

Dominant role of microglial and macrophage innate immune responses in human ischemic infarcts.

Zrzavy T, Machado-Santos J, Christine S, Baumgartner C, Weiner HL, Butovsky O, Lassmann H.

Brain Pathol. 2018 Nov;28(6):791-805. doi: 10.1111/bpa.12583. Epub 2017 Dec 28.

32.

Fibrinogen Activates BMP Signaling in Oligodendrocyte Progenitor Cells and Inhibits Remyelination after Vascular Damage.

Petersen MA, Ryu JK, Chang KJ, Etxeberria A, Bardehle S, Mendiola AS, Kamau-Devers W, Fancy SPJ, Thor A, Bushong EA, Baeza-Raja B, Syme CA, Wu MD, Rios Coronado PE, Meyer-Franke A, Yahn S, Pous L, Lee JK, Schachtrup C, Lassmann H, Huang EJ, Han MH, Absinta M, Reich DS, Ellisman MH, Rowitch DH, Chan JR, Akassoglou K.

Neuron. 2017 Dec 6;96(5):1003-1012.e7. doi: 10.1016/j.neuron.2017.10.008. Epub 2017 Nov 2.

33.

Human antibodies against the myelin oligodendrocyte glycoprotein can cause complement-dependent demyelination.

Peschl P, Schanda K, Zeka B, Given K, Böhm D, Ruprecht K, Saiz A, Lutterotti A, Rostásy K, Höftberger R, Berger T, Macklin W, Lassmann H, Bradl M, Bennett JL, Reindl M.

J Neuroinflammation. 2017 Oct 25;14(1):208. doi: 10.1186/s12974-017-0984-5.

34.

Targets of therapy in progressive MS.

Lassmann H.

Mult Scler. 2017 Oct;23(12):1593-1599. doi: 10.1177/1352458517729455. Review.

PMID:
29041864
35.

Immune-mediated disorders.

Höftberger R, Lassmann H.

Handb Clin Neurol. 2017;145:285-299. doi: 10.1016/B978-0-12-802395-2.00020-1. Review.

PMID:
28987176
36.

Inflammatory demyelinating diseases of the central nervous system.

Höftberger R, Lassmann H.

Handb Clin Neurol. 2017;145:263-283. doi: 10.1016/B978-0-12-802395-2.00019-5. Review.

PMID:
28987175
37.

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases.

Krasemann S, Madore C, Cialic R, Baufeld C, Calcagno N, El Fatimy R, Beckers L, O'Loughlin E, Xu Y, Fanek Z, Greco DJ, Smith ST, Tweet G, Humulock Z, Zrzavy T, Conde-Sanroman P, Gacias M, Weng Z, Chen H, Tjon E, Mazaheri F, Hartmann K, Madi A, Ulrich JD, Glatzel M, Worthmann A, Heeren J, Budnik B, Lemere C, Ikezu T, Heppner FL, Litvak V, Holtzman DM, Lassmann H, Weiner HL, Ochando J, Haass C, Butovsky O.

Immunity. 2017 Sep 19;47(3):566-581.e9. doi: 10.1016/j.immuni.2017.08.008.

38.

Targeting latency-associated peptide promotes antitumor immunity.

Gabriely G, da Cunha AP, Rezende RM, Kenyon B, Madi A, Vandeventer T, Skillin N, Rubino S, Garo L, Mazzola MA, Kolypetri P, Lanser AJ, Moreira T, Faria AMC, Lassmann H, Kuchroo V, Murugaiyan G, Weiner HL.

Sci Immunol. 2017 May 19;2(11). pii: eaaj1738. doi: 10.1126/sciimmunol.aaj1738.

39.

Loss of 'homeostatic' microglia and patterns of their activation in active multiple sclerosis.

Zrzavy T, Hametner S, Wimmer I, Butovsky O, Weiner HL, Lassmann H.

Brain. 2017 Jul 1;140(7):1900-1913. doi: 10.1093/brain/awx113.

40.

Oxidative Injury and Iron Redistribution Are Pathological Hallmarks of Marmoset Experimental Autoimmune Encephalomyelitis.

Dunham J, Bauer J, Campbell GR, Mahad DJ, van Driel N, van der Pol SMA, 't Hart BA, Lassmann H, Laman JD, van Horssen J, Kap YS.

J Neuropathol Exp Neurol. 2017 Jun 1;76(6):467-478. doi: 10.1093/jnen/nlx034.

PMID:
28505283
41.

Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia.

Karamita M, Barnum C, Möbius W, Tansey MG, Szymkowski DE, Lassmann H, Probert L.

JCI Insight. 2017 Apr 20;2(8). pii: 87455. doi: 10.1172/jci.insight.87455. eCollection 2017 Apr 20.

42.

Müller cells and retinal axons can be primary targets in experimental neuromyelitis optica spectrum disorder.

Zeka B, Lassmann H, Bradl M.

Clin Exp Neuroimmunol. 2017 Jan;8(Suppl Suppl 1):3-7. doi: 10.1111/cen3.12345. Epub 2017 Jan 11. Review.

43.

Pathogenic implications of distinct patterns of iron and zinc in chronic MS lesions.

Popescu BF, Frischer JM, Webb SM, Tham M, Adiele RC, Robinson CA, Fitz-Gibbon PD, Weigand SD, Metz I, Nehzati S, George GN, Pickering IJ, Brück W, Hametner S, Lassmann H, Parisi JE, Yong G, Lucchinetti CF.

Acta Neuropathol. 2017 Jul;134(1):45-64. doi: 10.1007/s00401-017-1696-8. Epub 2017 Mar 22.

44.

ADEM-like presentation, anti-MOG antibodies, and MS pathology: TWO case reports.

Körtvélyessy P, Breu M, Pawlitzki M, Metz I, Heinze HJ, Matzke M, Mawrin C, Rommer P, Kovacs GG, Mitter C, Reindl M, Brück W, Wandinger KP, Lassmann H, Höftberger R, Leypoldt F.

Neurol Neuroimmunol Neuroinflamm. 2017 Mar 14;4(3):e335. doi: 10.1212/NXI.0000000000000335. eCollection 2017 May. No abstract available.

45.

Recurrent tumefactive demyelinating lesions: a pathological study.

Türkoğlu R, Lassmann H, Aker FV, Tzartos J, Tzartos S, Tüzün E.

Clin Neuropathol. 2017 Jul/Aug;36(4):195-198. doi: 10.5414/NP301005. No abstract available.

PMID:
28211783
46.

An updated histological classification system for multiple sclerosis lesions.

Kuhlmann T, Ludwin S, Prat A, Antel J, Brück W, Lassmann H.

Acta Neuropathol. 2017 Jan;133(1):13-24. doi: 10.1007/s00401-016-1653-y. Epub 2016 Dec 17.

PMID:
27988845
47.

Use of Magnetic Resonance Imaging to Visualize Leptomeningeal Inflammation in Patients With Multiple Sclerosis: A Review.

Zurawski J, Lassmann H, Bakshi R.

JAMA Neurol. 2017 Jan 1;74(1):100-109. doi: 10.1001/jamaneurol.2016.4237. Review.

PMID:
27893883
48.

Differences in T cell cytotoxicity and cell death mechanisms between progressive multifocal leukoencephalopathy, herpes simplex virus encephalitis and cytomegalovirus encephalitis.

Laukoter S, Rauschka H, Tröscher AR, Köck U, Saji E, Jellinger K, Lassmann H, Bauer J.

Acta Neuropathol. 2017 Apr;133(4):613-627. doi: 10.1007/s00401-016-1642-1. Epub 2016 Nov 5.

49.

Slow expansion of multiple sclerosis iron rim lesions: pathology and 7 T magnetic resonance imaging.

Dal-Bianco A, Grabner G, Kronnerwetter C, Weber M, Höftberger R, Berger T, Auff E, Leutmezer F, Trattnig S, Lassmann H, Bagnato F, Hametner S.

Acta Neuropathol. 2017 Jan;133(1):25-42. doi: 10.1007/s00401-016-1636-z. Epub 2016 Oct 27.

50.

Complement C3 on microglial clusters in multiple sclerosis occur in chronic but not acute disease: Implication for disease pathogenesis.

Michailidou I, Naessens DM, Hametner S, Guldenaar W, Kooi EJ, Geurts JJ, Baas F, Lassmann H, Ramaglia V.

Glia. 2017 Feb;65(2):264-277. doi: 10.1002/glia.23090. Epub 2016 Oct 25.

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