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Items: 1 to 50 of 85

1.

Adenosine Receptor-Mediated Cardioprotection-Current Limitations and Future Directions.

Lasley RD.

Front Pharmacol. 2018 Apr 4;9:310. doi: 10.3389/fphar.2018.00310. eCollection 2018.

2.

Cholesterol Depletion Alters Cardiomyocyte Subcellular Signaling and Increases Contractility.

Haque MZ, McIntosh VJ, Abou Samra AB, Mohammad RM, Lasley RD.

PLoS One. 2016 Jul 21;11(7):e0154151. doi: 10.1371/journal.pone.0154151. eCollection 2016.

3.

A critical role of CXCR2 PDZ-mediated interactions in endothelial progenitor cell homing and angiogenesis.

Hou Y, Wu Y, Farooq SM, Guan X, Wang S, Liu Y, Oblak JJ, Holcomb J, Jiang Y, Strieter RM, Lasley RD, Arbab AS, Sun F, Li C, Yang Z.

Stem Cell Res. 2015 Mar;14(2):133-43. doi: 10.1016/j.scr.2014.12.001. Epub 2014 Dec 30.

4.

Adenosine inhibits renin release from juxtaglomerular cells via an A1 receptor-TRPC-mediated pathway.

Ortiz-Capisano MC, Atchison DK, Harding P, Lasley RD, Beierwaltes WH.

Am J Physiol Renal Physiol. 2013 Oct 15;305(8):F1209-19. doi: 10.1152/ajprenal.00710.2012. Epub 2013 Jul 24.

5.

Adenosine A1 receptors heterodimerize with β1- and β2-adrenergic receptors creating novel receptor complexes with altered G protein coupling and signaling.

Chandrasekera PC, Wan TC, Gizewski ET, Auchampach JA, Lasley RD.

Cell Signal. 2013 Apr;25(4):736-42. doi: 10.1016/j.cellsig.2012.12.022. Epub 2013 Jan 3.

6.

Adenosine A₂A and A₂B receptors are both required for adenosine A₁ receptor-mediated cardioprotection.

Zhan E, McIntosh VJ, Lasley RD.

Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H1183-9. doi: 10.1152/ajpheart.00264.2011. Epub 2011 Jul 8.

7.

Sex differences and the effects of ovariectomy on the β-adrenergic contractile response.

McIntosh VJ, Chandrasekera PC, Lasley RD.

Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H1127-34. doi: 10.1152/ajpheart.00711.2010. Epub 2011 Jun 17.

8.

Adenosine receptor-mediated cardioprotection: are all 4 subtypes required or redundant?

McIntosh VJ, Lasley RD.

J Cardiovasc Pharmacol Ther. 2012 Mar;17(1):21-33. doi: 10.1177/1074248410396877. Epub 2011 Feb 18. Review.

PMID:
21335481
9.

Invited commentary.

Lasley RD.

Ann Thorac Surg. 2010 Nov;90(5):1535-6. doi: 10.1016/j.athoracsur.2010.07.005. No abstract available.

PMID:
20971257
10.

Differential effects of adenosine A2a and A2b receptors on cardiac contractility.

Chandrasekera PC, McIntosh VJ, Cao FX, Lasley RD.

Am J Physiol Heart Circ Physiol. 2010 Dec;299(6):H2082-9. doi: 10.1152/ajpheart.00511.2010. Epub 2010 Oct 8.

11.

Adenosine receptors and membrane microdomains.

Lasley RD.

Biochim Biophys Acta. 2011 May;1808(5):1284-9. doi: 10.1016/j.bbamem.2010.09.019. Epub 2010 Oct 1. Review.

12.

Adenosine receptors and reperfusion injury of the heart.

Headrick JP, Lasley RD.

Handb Exp Pharmacol. 2009;(193):189-214. doi: 10.1007/978-3-540-89615-9_7. Review.

13.

Oxidative stress and adenosine A1 receptor activation differentially modulate subcellular cardiomyocyte MAPKs.

Ballard-Croft C, Locklar AC, Keith BJ, Mentzer RM Jr, Lasley RD.

Am J Physiol Heart Circ Physiol. 2008 Jan;294(1):H263-71. Epub 2007 Oct 26.

14.
15.

The A2a/A2b receptor antagonist ZM-241385 blocks the cardioprotective effect of adenosine agonist pretreatment in in vivo rat myocardium.

Lasley RD, Kristo G, Keith BJ, Mentzer RM Jr.

Am J Physiol Heart Circ Physiol. 2007 Jan;292(1):H426-31. Epub 2006 Sep 15.

16.

Regional myocardial ischemia-induced activation of MAPKs is associated with subcellular redistribution of caveolin and cholesterol.

Ballard-Croft C, Locklar AC, Kristo G, Lasley RD.

Am J Physiol Heart Circ Physiol. 2006 Aug;291(2):H658-67. Epub 2006 Mar 24.

17.

Aged rat myocardium exhibits normal adenosine receptor-mediated bradycardia and coronary vasodilation but increased adenosine agonist-mediated cardioprotection.

Kristo G, Yoshimura Y, Keith BJ, Mentzer RM Jr, Lasley RD.

J Gerontol A Biol Sci Med Sci. 2005 Nov;60(11):1399-404.

PMID:
16339325
18.

New insights into adenosine-mediated myocardial protection.

Lasley RD.

Br J Pharmacol. 2005 Jul;145(6):701-2. No abstract available.

19.

Delayed adenosine A1 receptor preconditioning in rat myocardium is MAPK dependent but iNOS independent.

Lasley RD, Keith BJ, Kristo G, Yoshimura Y, Mentzer RM Jr.

Am J Physiol Heart Circ Physiol. 2005 Aug;289(2):H785-91. Epub 2005 Apr 15.

20.

The p38 MAPK inhibitor SB203580 blocks adenosine A(1) receptor-induced attenuation of in vivo myocardial stunning.

Yoshimura Y, Kristo G, Keith BJ, Jahania SA, Mentzer RM Jr, Lasley RD.

Cardiovasc Drugs Ther. 2004 Nov;18(6):433-40.

PMID:
15770430
21.

In vivo adenosine receptor preconditioning reduces myocardial infarct size via subcellular ERK signaling.

Reid EA, Kristo G, Yoshimura Y, Ballard-Croft C, Keith BJ, Mentzer RM Jr, Lasley RD.

Am J Physiol Heart Circ Physiol. 2005 May;288(5):H2253-9. Epub 2005 Jan 14.

22.

Acute adenosine preconditioning is mediated by p38 MAPK activation in discrete subcellular compartments.

Ballard-Croft C, Kristo G, Yoshimura Y, Reid E, Keith BJ, Mentzer RM Jr, Lasley RD.

Am J Physiol Heart Circ Physiol. 2005 Mar;288(3):H1359-66. Epub 2004 Nov 11.

23.

The preischemic combination of the sodium-hydrogen exchanger inhibitor cariporide and the adenosine agonist AMP579 acts additively to reduce porcine myocardial infarct size.

Kristo G, Yoshimura Y, Ferraris SP, Jahania SA, Mentzer RM Jr, Lasley RD.

J Am Coll Surg. 2004 Oct;199(4):586-94.

PMID:
15454144
24.

Adenosine A1/A2a receptor agonist AMP-579 induces acute and delayed preconditioning against in vivo myocardial stunning.

Kristo G, Yoshimura Y, Keith BJ, Stevens RM, Jahania SA, Mentzer RM Jr, Lasley RD.

Am J Physiol Heart Circ Physiol. 2004 Dec;287(6):H2746-53. Epub 2004 Jul 22.

25.

Sodium-hydrogen exchange inhibition attenuates in vivo porcine myocardial stunning.

Stevens RM, Salik Jahania M, Mentzer RM Jr, Lasley RD.

Ann Thorac Surg. 2004 Feb;77(2):651-7.

PMID:
14759454
26.

The intermediary metabolite pyruvate attenuates stunning and reduces infarct size in in vivo porcine myocardium.

Kristo G, Yoshimura Y, Niu J, Keith BJ, Mentzer RM Jr, Bünger R, Lasley RD.

Am J Physiol Heart Circ Physiol. 2004 Feb;286(2):H517-24. Epub 2003 Oct 9.

27.

Differential cardiovascular regulatory activities of the alpha 1B- and alpha 1D-adrenoceptor subtypes.

Chalothorn D, McCune DF, Edelmann SE, Tobita K, Keller BB, Lasley RD, Perez DM, Tanoue A, Tsujimoto G, Post GR, Piascik MT.

J Pharmacol Exp Ther. 2003 Jun;305(3):1045-53. Epub 2003 Mar 20.

PMID:
12649302
28.

Intracellular sodium hydrogen exchange inhibition and clinical myocardial protection.

Mentzer RM Jr, Lasley RD, Jessel A, Karmazyn M.

Ann Thorac Surg. 2003 Feb;75(2):S700-8. Review.

PMID:
12607715
29.

Effects of in vivo myocardial ischemia and reperfusion on interstitial nitric oxide metabolites.

Stevens RM, Jahania MS, Stivers JE, Mentzer RM Jr, Lasley RD.

Ann Thorac Surg. 2002 Apr;73(4):1261-6.

PMID:
11998816
30.

Cardiac myocyte adenosine A2a receptor activation fails to alter cAMP or contractility: role of receptor localization.

Kilpatrick EL, Narayan P, Mentzer RM Jr, Lasley RD.

Am J Physiol Heart Circ Physiol. 2002 Mar;282(3):H1035-40.

31.

Cardiac myocyte adenosine receptors and caveolae.

Lasley RD, Smart EJ.

Trends Cardiovasc Med. 2001 Oct;11(7):259-63. Review.

PMID:
11709278
32.

Annexin V staining during reperfusion detects cardiomyocytes with unique properties.

Narayan P, Mentzer RM Jr, Lasley RD.

Am J Physiol Heart Circ Physiol. 2001 Nov;281(5):H1931-7.

33.

Adenosine A3 agonist cardioprotection in isolated rat and rabbit hearts is blocked by the A1 antagonist DPCPX.

Kilpatrick EL, Narayan P, Mentzer RM Jr, Lasley RD.

Am J Physiol Heart Circ Physiol. 2001 Aug;281(2):H847-53.

34.

Novel short-acting A2A adenosine receptor agonists for coronary vasodilation: inverse relationship between affinity and duration of action of A2A agonists.

Gao Z, Li Z, Baker SP, Lasley RD, Meyer S, Elzein E, Palle V, Zablocki JA, Blackburn B, Belardinelli L.

J Pharmacol Exp Ther. 2001 Jul;298(1):209-18.

PMID:
11408544
35.

Beneficial effects of adenosine A(2a) agonist CGS-21680 in infarcted and stunned porcine myocardium.

Lasley RD, Jahania MS, Mentzer RM Jr.

Am J Physiol Heart Circ Physiol. 2001 Apr;280(4):H1660-6.

36.

Acute allograft failure in thoracic organ transplantation.

Jahania MS, Mullett TW, Sanchez JA, Narayan P, Lasley RD, Mentzer RM Jr.

J Card Surg. 2000 Mar-Apr;15(2):122-8. Review.

PMID:
11221970
37.

Adenosine A1 receptor activation reduces reactive oxygen species and attenuates stunning in ventricular myocytes.

Narayan P, Mentzer RM Jr, Lasley RD.

J Mol Cell Cardiol. 2001 Jan;33(1):121-9.

PMID:
11133228
38.

Activated cardiac adenosine A(1) receptors translocate out of caveolae.

Lasley RD, Narayan P, Uittenbogaard A, Smart EJ.

J Biol Chem. 2000 Feb 11;275(6):4417-21.

39.

Phosphatase inhibitor cantharidin blocks adenosine A(1) receptor anti-adrenergic effect in rat cardiac myocytes.

Narayan P, Mentzer RM Jr, Lasley RD.

Am J Physiol Heart Circ Physiol. 2000 Jan;278(1):H1-7.

40.

Metabolic inotropy and calcium transients in isolated rat cardiomyocytes.

Lasley RD, Martin BJ, Valdivia HH, Mentzer RM Jr, Bünger R.

Ann N Y Acad Sci. 1998 Sep 16;853:308-10. No abstract available.

PMID:
10603966
41.

Heart preservation for transplantation: principles and strategies.

Jahania MS, Sanchez JA, Narayan P, Lasley RD, Mentzer RM Jr.

Ann Thorac Surg. 1999 Nov;68(5):1983-7. Review.

PMID:
10585116
42.

Effects of adenosine and acadesine on interstitial nucleosides and myocardial stunning in the pig.

Lasley RD, Randhawa MP Jr, Hegge JO, Mentzer RM.

Can J Physiol Pharmacol. 1999 Apr;77(4):259-67.

PMID:
10535674
43.
44.

Species-dependent hemodynamic effects of adenosine A3-receptor agonists IB-MECA and Cl-IB-MECA.

Lasley RD, Narayan P, Jahania MS, Partin EL, Kraft KR, Mentzer RM Jr.

Am J Physiol. 1999 Jun;276(6):H2076-84. doi: 10.1152/ajpheart.1999.276.6.H2076.

PMID:
10362690
45.

Adenosine myocardial protection: preliminary results of a phase II clinical trial.

Mentzer RM Jr, Birjiniuk V, Khuri S, Lowe JE, Rahko PS, Weisel RD, Wellons HA, Barker ML, Lasley RD.

Ann Surg. 1999 May;229(5):643-9; discussion 649-50.

46.
47.

Adenosine attenuates in vivo myocardial stunning with minimal effects on cardiac energetics.

Lasley RD, Zhou Z, Hegge JO, Bünger R, Mentzer RM Jr.

Basic Res Cardiol. 1998 Aug;93(4):303-12.

PMID:
9782373
48.
49.

Comparison of interstitial fluid and coronary venous adenosine levels in in vivo porcine myocardium.

Lasley RD, Hegge JO, Noble MA, Mentzer RM Jr.

J Mol Cell Cardiol. 1998 Jun;30(6):1137-47.

PMID:
9689588
50.

Myocardial preconditioning produced by ischemia, hypoxia, and a KATP channel opener: effects on interstitial adenosine in dogs.

Mei DA, Nithipatikom K, Lasley RD, Gross GJ.

J Mol Cell Cardiol. 1998 Jun;30(6):1225-36.

PMID:
9689596

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