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Items: 1 to 50 of 96

1.

A specificity map for the PDZ domain family.

Tonikian R, Zhang Y, Sazinsky SL, Currell B, Yeh JH, Reva B, Held HA, Appleton BA, Evangelista M, Wu Y, Xin X, Chan AC, Seshagiri S, Lasky LA, Sander C, Boone C, Bader GD, Sidhu SS.

PLoS Biol. 2008 Sep 30;6(9):e239. doi: 10.1371/journal.pbio.0060239.

2.

Convergent and divergent ligand specificity among PDZ domains of the LAP and zonula occludens (ZO) families.

Zhang Y, Yeh S, Appleton BA, Held HA, Kausalya PJ, Phua DC, Wong WL, Lasky LA, Wiesmann C, Hunziker W, Sidhu SS.

J Biol Chem. 2006 Aug 4;281(31):22299-311. Epub 2006 May 31.

3.

Identification of a massive reserve of hematopoietic progenitors in mice.

Broxmeyer HE, Cooper S, Lasky LA, De Sauvage F.

Stem Cells Dev. 2005 Apr;14(2):105-10.

PMID:
15910237
5.

Origins of PDZ domain ligand specificity. Structure determination and mutagenesis of the Erbin PDZ domain.

Skelton NJ, Koehler MF, Zobel K, Wong WL, Yeh S, Pisabarro MT, Yin JP, Lasky LA, Sidhu SS.

J Biol Chem. 2003 Feb 28;278(9):7645-54. Epub 2002 Nov 20.

6.

Prostate stem cell antigen as therapy target: tissue expression and in vivo efficacy of an immunoconjugate.

Ross S, Spencer SD, Holcomb I, Tan C, Hongo J, Devaux B, Rangell L, Keller GA, Schow P, Steeves RM, Lutz RJ, Frantz G, Hillan K, Peale F, Tobin P, Eberhard D, Rubin MA, Lasky LA, Koeppen H.

Cancer Res. 2002 May 1;62(9):2546-53.

7.

MAGI-1: a widely expressed, alternatively spliced tight junction protein.

Laura RP, Ross S, Koeppen H, Lasky LA.

Exp Cell Res. 2002 May 1;275(2):155-70.

PMID:
11969287
8.

The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF.

Laura RP, Witt AS, Held HA, Gerstner R, Deshayes K, Koehler MF, Kosik KS, Sidhu SS, Lasky LA.

J Biol Chem. 2002 Apr 12;277(15):12906-14. Epub 2002 Jan 30.

9.

The forkhead transcription factor AFX activates apoptosis by induction of the BCL-6 transcriptional repressor.

Tang TT, Dowbenko D, Jackson A, Toney L, Lewin DA, Dent AL, Lasky LA.

J Biol Chem. 2002 Apr 19;277(16):14255-65. Epub 2002 Jan 2.

10.

AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival.

Li Y, Dowbenko D, Lasky LA.

J Biol Chem. 2002 Mar 29;277(13):11352-61. Epub 2001 Dec 27.

11.

PSTPIP is a substrate of PTP-PEST and serves as a scaffold guiding PTP-PEST toward a specific dephosphorylation of WASP.

Côté JF, Chung PL, Théberge JF, Hallé M, Spencer S, Lasky LA, Tremblay ML.

J Biol Chem. 2002 Jan 25;277(4):2973-86. Epub 2001 Nov 15.

12.

Regulation of the association between PSTPIP and CD2 in murine T cells.

Bai Y, Ding Y, Spencer S, Lasky LA, Bromberg JS.

Exp Mol Pathol. 2001 Oct;71(2):115-24.

PMID:
11599917
13.

ALCAM (CD166): its role in hematopoietic and endothelial development.

Ohneda O, Ohneda K, Arai F, Lee J, Miyamoto T, Fukushima Y, Dowbenko D, Lasky LA, Suda T.

Blood. 2001 Oct 1;98(7):2134-42.

PMID:
11568000
14.

CrkL is an adapter for Wiskott-Aldrich syndrome protein and Syk.

Oda A, Ochs HD, Lasky LA, Spencer S, Ozaki K, Fujihara M, Handa M, Ikebuchi K, Ikeda H.

Blood. 2001 May 1;97(9):2633-9.

PMID:
11313252
15.

PTEN 2, a Golgi-associated testis-specific homologue of the PTEN tumor suppressor lipid phosphatase.

Wu Y, Dowbenko D, Pisabarro MT, Dillard-Telm L, Koeppen H, Lasky LA.

J Biol Chem. 2001 Jun 15;276(24):21745-53. Epub 2001 Mar 2.

16.

Caenorhabditis elegans PIAK, a phospholipid-independent kinase that activates the AKT/PKB survival kinase.

Li Y, Dowbenko D, Lasky LA.

J Biol Chem. 2001 Jun 8;276(23):20323-9. Epub 2001 Mar 23.

18.

Cytoskeletal protein PSTPIP1 directs the PEST-type protein tyrosine phosphatase to the c-Abl kinase to mediate Abl dephosphorylation.

Cong F, Spencer S, Côté JF, Wu Y, Tremblay ML, Lasky LA, Goff SP.

Mol Cell. 2000 Dec;6(6):1413-23.

19.

Pharmaceutical biotechnology. The genomes are just the beginning

Lawn RM, Lasky LA.

Curr Opin Biotechnol. 2000 Dec;11(6):579-80. No abstract available.

PMID:
11102792
20.

Analysis of PDZ domain-ligand interactions using carboxyl-terminal phage display.

Fuh G, Pisabarro MT, Li Y, Quan C, Lasky LA, Sidhu SS.

J Biol Chem. 2000 Jul 14;275(28):21486-91.

21.

The nucleoskeleton: go EAST, young man.

Lasky LA.

Nat Cell Biol. 2000 May;2(5):E74-6. Review. No abstract available.

PMID:
10806487
22.

Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase.

Wu Y, Dowbenko D, Spencer S, Laura R, Lee J, Gu Q, Lasky LA.

J Biol Chem. 2000 Jul 14;275(28):21477-85.

23.

WECHE: a novel hematopoietic regulatory factor.

Ohneda O, Ohneda K, Nomiyama H, Zheng Z, Gold SA, Arai F, Miyamoto T, Taillon BE, McIndoe RA, Shimkets RA, Lewin DA, Suda T, Lasky LA.

Immunity. 2000 Feb;12(2):141-50.

24.

Multicolor immunofluorescence and flow cytometry utilizing cascade blue to purify murine hematopoietic stem cells from fetal liver and bone marrow.

Donahue CJ, Fennie C, Villacorta R, La H, Lasky LA, Ohneda O.

Cytometry. 1999 Sep 1;37(1):60-7.

PMID:
10451507
25.

Protein tyrosine phosphatase-PEST regulates focal adhesion disassembly, migration, and cytokinesis in fibroblasts.

Angers-Loustau A, Côté JF, Charest A, Dowbenko D, Spencer S, Lasky LA, Tremblay ML.

J Cell Biol. 1999 Mar 8;144(5):1019-31.

26.
27.

Hematopoietic stem cell maintenance and differentiation are supported by embryonic aorta-gonad-mesonephros region-derived endothelium.

Ohneda O, Fennie C, Zheng Z, Donahue C, La H, Villacorta R, Cairns B, Lasky LA.

Blood. 1998 Aug 1;92(3):908-19.

PMID:
9680359
30.

How integrins are activated.

Lasky LA.

Nature. 1997 Nov 6;390(6655):15, 17. No abstract available.

PMID:
9363883
31.

PSTPIP: a tyrosine phosphorylated cleavage furrow-associated protein that is a substrate for a PEST tyrosine phosphatase.

Spencer S, Dowbenko D, Cheng J, Li W, Brush J, Utzig S, Simanis V, Lasky LA.

J Cell Biol. 1997 Aug 25;138(4):845-60.

32.

A novel protein-tyrosine phosphatase related to the homotypically adhering kappa and mu receptors.

Cheng J, Wu K, Armanini M, O'Rourke N, Dowbenko D, Lasky LA.

J Biol Chem. 1997 Mar 14;272(11):7264-77.

33.

Hematopoiesis: wandering progenitor cells.

Lasky LA.

Curr Biol. 1996 Oct 1;6(10):1238-40. Review.

34.

Characterization of a novel member of the macrophage mannose receptor type C lectin family.

Wu K, Yuan J, Lasky LA.

J Biol Chem. 1996 Aug 30;271(35):21323-30.

35.

A novel protein tyrosine phosphatase expressed in lin(lo)CD34(hi)Sca(hi) hematopoietic progenitor cells.

Cheng J, Daimaru L, Fennie C, Lasky LA.

Blood. 1996 Aug 15;88(4):1156-67.

PMID:
8695832
36.

Hematopoietic defects in mice lacking the sialomucin CD34.

Cheng J, Baumhueter S, Cacalano G, Carver-Moore K, Thibodeaux H, Thomas R, Broxmeyer HE, Cooper S, Hague N, Moore M, Lasky LA.

Blood. 1996 Jan 15;87(2):479-90.

PMID:
8555469
37.
38.

From sticky zippers to morphology.

Lasky LA.

Nat Struct Biol. 1995 Apr;2(4):258-61. No abstract available.

PMID:
7796258
39.

Sialomucins in inflammation and hematopoiesis.

Lasky LA.

Adv Exp Med Biol. 1995;376:259. No abstract available.

PMID:
8597256
40.
41.

The sialomucin CD34 is expressed on hematopoietic cells and blood vessels during murine development.

Young PE, Baumhueter S, Lasky LA.

Blood. 1995 Jan 1;85(1):96-105.

PMID:
7528578
42.

Global vascular expression of murine CD34, a sialomucin-like endothelial ligand for L-selectin.

Baumhueter S, Dybdal N, Kyle C, Lasky LA.

Blood. 1994 Oct 15;84(8):2554-65.

PMID:
7522633
43.

A liquid-phase binding analysis for L-selectin. A strong dependency on highly clustered sulfate groups.

Yoshida T, Fennie C, Lasky LA, Lee YC.

Eur J Biochem. 1994 Jun 1;222(2):703-9.

44.

A sweet success.

Lasky LA.

Nat Struct Biol. 1994 Mar;1(3):139-41. No abstract available.

PMID:
7544682
45.

Sialomucin ligands for selectins: a new family of cell adhesion molecules.

Lasky LA.

Princess Takamatsu Symp. 1994;24:81-90. Review.

PMID:
8983065
46.

Expression of GlyCAM-1, an endothelial ligand for L-selectin, is affected by afferent lymphatic flow.

Mebius RE, Dowbenko D, Williams A, Fennie C, Lasky LA, Watson SR.

J Immunol. 1993 Dec 15;151(12):6769-76.

PMID:
7505014
47.

Binding of L-selectin to the vascular sialomucin CD34.

Baumheter S, Singer MS, Henzel W, Hemmerich S, Renz M, Rosen SD, Lasky LA.

Science. 1993 Oct 15;262(5132):436-8.

PMID:
7692600
48.

A 'roll' in acute inflammation.

Lasky LA.

Curr Biol. 1993 Oct 1;3(10):680-2. No abstract available.

PMID:
15335860
49.
50.

Cloning of a rat homologue of mouse GlyCAM 1 reveals conservation of structural domains.

Dowbenko D, Watson SR, Lasky LA.

J Biol Chem. 1993 Jul 5;268(19):14399-403.

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