Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 137

1.
2.

Obesity-related endometrial cancer: an update on survivorship approaches to reducing cardiovascular death.

Laskey RA, McCarroll ML, von Gruenigen VE.

BJOG. 2016 Jan;123(2):293-8. doi: 10.1111/1471-0528.13684. Review.

3.

Control of mammalian gene expression by selective mRNA export.

Wickramasinghe VO, Laskey RA.

Nat Rev Mol Cell Biol. 2015 Jul;16(7):431-42. doi: 10.1038/nrm4010. Epub 2015 Jun 17. Review.

PMID:
26081607
4.

National Cancer Data Base analysis of radiation therapy consolidation modality for cervical cancer: the impact of new technological advancements.

Gill BS, Lin JF, Krivak TC, Sukumvanich P, Laskey RA, Ross MS, Lesnock JL, Beriwal S.

Int J Radiat Oncol Biol Phys. 2014 Dec 1;90(5):1083-90. doi: 10.1016/j.ijrobp.2014.07.017. Epub 2014 Sep 9.

PMID:
25216857
5.

Retreatment with bevacizumab in patients with gynecologic malignancy is associated with clinical response and does not increase morbidity.

Laskey RA, Richard SD, Smith AL, Lin JF, Beck TL, Lesnock JL, Kelley JL 3rd, Olawaiye AB, Sukumvanich P, Krivak TC.

Onco Targets Ther. 2014 Mar 21;7:469-76. doi: 10.2147/OTT.S57425. eCollection 2014.

6.

Selective nuclear export of specific classes of mRNA from mammalian nuclei is promoted by GANP.

Wickramasinghe VO, Andrews R, Ellis P, Langford C, Gurdon JB, Stewart M, Venkitaraman AR, Laskey RA.

Nucleic Acids Res. 2014 Apr;42(8):5059-71. doi: 10.1093/nar/gku095. Epub 2014 Feb 7.

7.

Human inositol polyphosphate multikinase regulates transcript-selective nuclear mRNA export to preserve genome integrity.

Wickramasinghe VO, Savill JM, Chavali S, Jonsdottir AB, Rajendra E, Grüner T, Laskey RA, Babu MM, Venkitaraman AR.

Mol Cell. 2013 Sep 26;51(6):737-50. doi: 10.1016/j.molcel.2013.08.031.

8.

Replication proteins and human disease.

Jackson AP, Laskey RA, Coleman N.

Cold Spring Harb Perspect Biol. 2014 Jan 1;6(1). pii: a013060. doi: 10.1101/cshperspect.a013060. Review.

9.

Obesity as a risk for the recurrence of anterior vaginal wall prolapse after anterior colporrhaphy.

Kawasaki A, Corey EG, Laskey RA, Weidner AC, Siddiqui NY, Wu JM.

J Reprod Med. 2013 May-Jun;58(5-6):195-9.

PMID:
23763002
10.

Predictors of reduced relative dose intensity and its relationship to mortality in women receiving multi-agent chemotherapy for epithelial ovarian cancer.

Hanna RK, Poniewierski MS, Laskey RA, Lopez MA, Shafer A, Van Le L, Crawford J, Dale DC, Gehrig PA, Secord AA, Havrilesky LJ, Lyman GH.

Gynecol Oncol. 2013 Apr;129(1):74-80. doi: 10.1016/j.ygyno.2012.12.017. Epub 2012 Dec 21.

PMID:
23262376
11.

Diagnosis of bladder cancer by immunocytochemical detection of minichromosome maintenance protein-2 in cells retrieved from urine.

Saeb-Parsy K, Wilson A, Scarpini C, Corcoran M, Chilcott S, McKean M, Thottakam B, Rai B, Nabi G, Rana D, Perera M, Stewart K, Laskey RA, Neal DE, Coleman N.

Br J Cancer. 2012 Oct 9;107(8):1384-91. doi: 10.1038/bjc.2012.381. Epub 2012 Sep 11.

12.

Predictors of severe and febrile neutropenia during primary chemotherapy for ovarian cancer.

Laskey RA, Poniewierski MS, Lopez MA, Hanna RK, Secord AA, Gehrig PA, Lyman GH, Havrilesky LJ.

Gynecol Oncol. 2012 Jun;125(3):625-30. doi: 10.1016/j.ygyno.2012.03.015. Epub 2012 Mar 15.

PMID:
22426251
13.

Distinct activities of the anaphase-promoting complex/cyclosome (APC/C) in mouse embryonic cells.

Yang VS, Carter SA, Ng Y, Hyland SJ, Tachibana-Konwalski K, Fisher RA, Sebire NJ, Seckl MJ, Pedersen RA, Laskey RA, Gonzalez MA.

Cell Cycle. 2012 Mar 1;11(5):846-55. doi: 10.4161/cc.11.5.19251. Epub 2012 Mar 1.

14.

Functional and structural characterization of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export.

Jani D, Lutz S, Hurt E, Laskey RA, Stewart M, Wickramasinghe VO.

Nucleic Acids Res. 2012 May;40(10):4562-73. doi: 10.1093/nar/gks059. Epub 2012 Feb 4.

15.

Geminin escapes degradation in G1 of mouse pluripotent cells and mediates the expression of Oct4, Sox2, and Nanog.

Yang VS, Carter SA, Hyland SJ, Tachibana-Konwalski K, Laskey RA, Gonzalez MA.

Curr Biol. 2011 Apr 26;21(8):692-9. doi: 10.1016/j.cub.2011.03.026. Epub 2011 Apr 14.

16.

GANP enhances the efficiency of mRNA nuclear export in mammalian cells.

Wickramasinghe VO, Stewart M, Laskey RA.

Nucleus. 2010 Sep-Oct;1(5):393-6. doi: 10.4161/nucl.1.5.12351.

17.

MCM3AP is transcribed from a promoter within an intron of the overlapping gene for GANP.

Wickramasinghe VO, McMurtrie PI, Marr J, Amagase Y, Main S, Mills AD, Laskey RA, Takei Y.

J Mol Biol. 2011 Feb 25;406(3):355-61. doi: 10.1016/j.jmb.2010.12.035. Epub 2010 Dec 30.

18.

mRNA export from mammalian cell nuclei is dependent on GANP.

Wickramasinghe VO, McMurtrie PI, Mills AD, Takei Y, Penrhyn-Lowe S, Amagase Y, Main S, Marr J, Stewart M, Laskey RA.

Curr Biol. 2010 Jan 12;20(1):25-31. doi: 10.1016/j.cub.2009.10.078. Epub 2009 Dec 10.

19.

Minichromosome maintenance proteins in cancer screening.

Coleman N, Laskey RA.

Eur J Cancer. 2009 Sep;45 Suppl 1:416-7. doi: 10.1016/S0959-8049(09)70071-1. No abstract available.

PMID:
19775653
20.

Isolation of stool-derived mucus provides a high yield of colonocytes suitable for early detection of colorectal carcinoma.

White V, Scarpini C, Barbosa-Morais NL, Ikelle E, Carter S, Laskey RA, Miller R, Coleman N.

Cancer Epidemiol Biomarkers Prev. 2009 Jul;18(7):2006-13. doi: 10.1158/1055-9965.EPI-08-1145.

21.

Loss of p21 CDKN1A impairs entry to quiescence and activates a DNA damage response in normal fibroblasts induced to quiescence.

Perucca P, Cazzalini O, Madine M, Savio M, Laskey RA, Vannini V, Prosperi E, Stivala LA.

Cell Cycle. 2009 Jan 1;8(1):105-14. Epub 2009 Jan 1.

PMID:
19106607
22.

Improved screening for anal neoplasia by immunocytochemical detection of minichromosome maintenance proteins.

Scarpini C, White V, Muralidhar B, Patterson A, Hickey N, Singh N, Mullerat J, Winslet M, Davies RJ, Phillips ML, Stacey P, Laskey RA, Miller R, Nathan M, Coleman N.

Cancer Epidemiol Biomarkers Prev. 2008 Oct;17(10):2855-64. doi: 10.1158/1055-9965.EPI-08-0288.

23.

The extracellular matrix protein TGFBI induces microtubule stabilization and sensitizes ovarian cancers to paclitaxel.

Ahmed AA, Mills AD, Ibrahim AE, Temple J, Blenkiron C, Vias M, Massie CE, Iyer NG, McGeoch A, Crawford R, Nicke B, Downward J, Swanton C, Bell SD, Earl HM, Laskey RA, Caldas C, Brenton JD.

Cancer Cell. 2007 Dec;12(6):514-27.

24.

MCM immunocytochemistry as a first line cervical screening test in developing countries: a prospective cohort study in a regional cancer centre in India.

Mukherjee G, Muralidhar B, Bafna UD, Laskey RA, Coleman N.

Br J Cancer. 2007 Apr 10;96(7):1107-11. Epub 2007 Mar 6.

25.

Geminin is essential to prevent endoreduplication and to form pluripotent cells during mammalian development.

Gonzalez MA, Tachibana KE, Adams DJ, van der Weyden L, Hemberger M, Coleman N, Bradley A, Laskey RA.

Genes Dev. 2006 Jul 15;20(14):1880-4.

26.

A minimally invasive immunocytochemical approach to early detection of oral squamous cell carcinoma and dysplasia.

Scott IS, Odell E, Chatrath P, Morris LS, Davies RJ, Vowler SL, Laskey RA, Coleman N.

Br J Cancer. 2006 Apr 24;94(8):1170-5.

27.

Depletion of licensing inhibitor geminin causes centrosome overduplication and mitotic defects.

Tachibana KE, Gonzalez MA, Guarguaglini G, Nigg EA, Laskey RA.

EMBO Rep. 2005 Nov;6(11):1052-7. Epub 2005 Sep 23.

28.

Organization of the archaeal MCM complex on DNA and implications for the helicase mechanism.

McGeoch AT, Trakselis MA, Laskey RA, Bell SD.

Nat Struct Mol Biol. 2005 Sep;12(9):756-62. Epub 2005 Aug 14.

PMID:
16116441
29.

Control of DNA replication and its potential clinical exploitation.

Gonzalez MA, Tachibana KE, Laskey RA, Coleman N.

Nat Rev Cancer. 2005 Feb;5(2):135-41. doi: 10.1038/nrc1548. Review.

PMID:
15660109
30.

Geminin predicts adverse clinical outcome in breast cancer by reflecting cell-cycle progression.

Gonzalez MA, Tachibana KE, Chin SF, Callagy G, Madine MA, Vowler SL, Pinder SE, Laskey RA, Coleman N.

J Pathol. 2004 Oct;204(2):121-30.

PMID:
15376260
31.

Minichromosome maintenance protein 2 is a strong independent prognostic marker in breast cancer.

Gonzalez MA, Pinder SE, Callagy G, Vowler SL, Morris LS, Bird K, Bell JA, Laskey RA, Coleman N.

J Clin Oncol. 2003 Dec 1;21(23):4306-13.

PMID:
14645419
32.

A novel immunohistochemical method to estimate cell-cycle phase distribution in archival tissue: implications for the prediction of outcome in colorectal cancer.

Scott IS, Morris LS, Bird K, Davies RJ, Vowler SL, Rushbrook SM, Marshall AE, Laskey RA, Miller R, Arends MJ, Coleman N.

J Pathol. 2003 Oct;201(2):187-97.

PMID:
14517835
33.

Aberrant expression of minichromosome maintenance protein-2 and Ki67 in laryngeal squamous epithelial lesions.

Chatrath P, Scott IS, Morris LS, Davies RJ, Rushbrook SM, Bird K, Vowler SL, Grant JW, Saeed IT, Howard D, Laskey RA, Coleman N.

Br J Cancer. 2003 Sep 15;89(6):1048-54.

34.

Minichromosome maintenance (Mcm) proteins, cyclin B1 and D1, phosphohistone H3 and in situ DNA replication for functional analysis of vulval intraepithelial neoplasia.

Davidson EJ, Morris LS, Scott IS, Rushbrook SM, Bird K, Laskey RA, Wilson GE, Kitchener HC, Coleman N, Stern PL.

Br J Cancer. 2003 Jan 27;88(2):257-62.

35.

Human replication protein Cdc6 prevents mitosis through a checkpoint mechanism that implicates Chk1.

Clay-Farrace L, Pelizon C, Santamaria D, Pines J, Laskey RA.

EMBO J. 2003 Feb 3;22(3):704-12.

36.
37.

Regulatable killing of eukaryotic cells by the prokaryotic proteins Kid and Kis.

de la Cueva-Méndez G, Mills AD, Clay-Farrace L, Díaz-Orejas R, Laskey RA.

EMBO J. 2003 Jan 15;22(2):246-51.

38.

Human replication protein Cdc6 is selectively cleaved by caspase 3 during apoptosis.

Pelizon C, d'Adda di Fagagna F, Farrace L, Laskey RA.

EMBO Rep. 2002 Aug;3(8):780-4. Epub 2002 Jul 15.

39.

Distinct roles for cyclins E and A during DNA replication complex assembly and activation.

Coverley D, Laman H, Laskey RA.

Nat Cell Biol. 2002 Jul;4(7):523-8.

PMID:
12080347
40.

Analysis of minichromosome maintenance proteins as a novel method for detection of colorectal cancer in stool.

Davies RJ, Freeman A, Morris LS, Bingham S, Dilworth S, Scott I, Laskey RA, Miller R, Coleman N.

Lancet. 2002 Jun 1;359(9321):1917-9.

PMID:
12057556
41.

Early recurrence of benign meningioma correlates with expression of mini-chromosome maintenance-2 protein.

Hunt DP, Freeman A, Morris LS, Burnet NG, Bird K, Davies TW, Laskey RA, Coleman N.

Br J Neurosurg. 2002 Feb;16(1):10-5.

PMID:
11928726
42.

Unphosphorylatable mutants of Cdc6 disrupt its nuclear export but still support DNA replication once per cell cycle.

Pelizon C, Madine MA, Romanowski P, Laskey RA.

Genes Dev. 2000 Oct 1;14(19):2526-33.

43.
44.

The roles of the MCM, ORC, and Cdc6 proteins in determining the replication competence of chromatin in quiescent cells.

Madine MA, Swietlik M, Pelizon C, Romanowski P, Mills AD, Laskey RA.

J Struct Biol. 2000 Apr;129(2-3):198-210.

PMID:
10806069
45.

Detection of S-phase cells in tissue sections by in situ DNA replication.

Mills AD, Coleman N, Morris LS, Laskey RA.

Nat Cell Biol. 2000 Apr;2(4):244-5. No abstract available.

PMID:
10783244
46.

Nuclear chaperones.

Philpott A, Krude T, Laskey RA.

Semin Cell Dev Biol. 2000 Feb;11(1):7-14. Review.

PMID:
10736259
47.

Interaction of Xenopus Cdc2 x cyclin A1 with the origin recognition complex.

Romanowski P, Marr J, Madine MA, Rowles A, Blow JJ, Gautier J, Laskey RA.

J Biol Chem. 2000 Feb 11;275(6):4239-43.

48.

Immunoassay for urothelial cancers that detects DNA replication protein Mcm5 in urine.

Stoeber K, Halsall I, Freeman A, Swinn R, Doble A, Morris L, Coleman N, Bullock N, Laskey RA, Hales CN, Williams GH.

Lancet. 1999 Oct 30;354(9189):1524-5.

PMID:
10551502
49.

Minichromosome maintenance proteins as biological markers of dysplasia and malignancy.

Freeman A, Morris LS, Mills AD, Stoeber K, Laskey RA, Williams GH, Coleman N.

Clin Cancer Res. 1999 Aug;5(8):2121-32.

50.

CIBA Medal Lecture. Regulatory roles of the nuclear membrane.

Laskey RA.

Biochem Soc Trans. 1998 Nov;26(4):561-7. No abstract available.

PMID:
10047782

Supplemental Content

Loading ...
Support Center