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Items: 1 to 50 of 114

1.

Identification and reconstruction of novel antibiotic resistance genes from metagenomes.

Berglund F, Österlund T, Boulund F, Marathe NP, Larsson DGJ, Kristiansson E.

Microbiome. 2019 Apr 1;7(1):52. doi: 10.1186/s40168-019-0670-1.

2.

Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage.

Hendriksen RS, Munk P, Njage P, van Bunnik B, McNally L, Lukjancenko O, Röder T, Nieuwenhuijse D, Pedersen SK, Kjeldgaard J, Kaas RS, Clausen PTLC, Vogt JK, Leekitcharoenphon P, van de Schans MGM, Zuidema T, de Roda Husman AM, Rasmussen S, Petersen B; Global Sewage Surveillance project consortium, Amid C, Cochrane G, Sicheritz-Ponten T, Schmitt H, Alvarez JRM, Aidara-Kane A, Pamp SJ, Lund O, Hald T, Woolhouse M, Koopmans MP, Vigre H, Petersen TN, Aarestrup FM.

Nat Commun. 2019 Mar 8;10(1):1124. doi: 10.1038/s41467-019-08853-3.

3.

CMY-1/MOX-family AmpC β-lactamases MOX-1, MOX-2 and MOX-9 were mobilized independently from three Aeromonas species.

Ebmeyer S, Kristiansson E, Larsson DGJ.

J Antimicrob Chemother. 2019 Feb 7. doi: 10.1093/jac/dkz025. [Epub ahead of print]

4.

Fecal pollution can explain antibiotic resistance gene abundances in anthropogenically impacted environments.

Karkman A, Pärnänen K, Larsson DGJ.

Nat Commun. 2019 Jan 8;10(1):80. doi: 10.1038/s41467-018-07992-3.

5.

Characterization of the First OXA-10 Natural Variant with Increased Carbapenemase Activity.

Kotsakis SD, Flach CF, Razavi M, Larsson DGJ.

Antimicrob Agents Chemother. 2018 Dec 21;63(1). pii: e01817-18. doi: 10.1128/AAC.01817-18. Print 2019 Jan.

PMID:
30397053
6.

PER extended-spectrum β-lactamases originate from Pararheinheimera spp.

Ebmeyer S, Kristiansson E, Larsson DGJ.

Int J Antimicrob Agents. 2019 Feb;53(2):158-164. doi: 10.1016/j.ijantimicag.2018.10.019. Epub 2018 Nov 2.

PMID:
30395985
7.

Maternal gut and breast milk microbiota affect infant gut antibiotic resistome and mobile genetic elements.

Pärnänen K, Karkman A, Hultman J, Lyra C, Bengtsson-Palme J, Larsson DGJ, Rautava S, Isolauri E, Salminen S, Kumar H, Satokari R, Virta M.

Nat Commun. 2018 Sep 24;9(1):3891. doi: 10.1038/s41467-018-06393-w.

8.

Critical knowledge gaps and research needs related to the environmental dimensions of antibiotic resistance.

Larsson DGJ, Andremont A, Bengtsson-Palme J, Brandt KK, de Roda Husman AM, Fagerstedt P, Fick J, Flach CF, Gaze WH, Kuroda M, Kvint K, Laxminarayan R, Manaia CM, Nielsen KM, Plant L, Ploy MC, Segovia C, Simonet P, Smalla K, Snape J, Topp E, van Hengel AJ, Verner-Jeffreys DW, Virta MPJ, Wellington EM, Wernersson AS.

Environ Int. 2018 Aug;117:132-138. doi: 10.1016/j.envint.2018.04.041. Epub 2018 May 7.

9.

Effects of ozonated sewage effluent on reproduction and behavioral endpoints in zebrafish (Danio rerio).

Pohl J, Björlenius B, Brodin T, Carlsson G, Fick J, Larsson DGJ, Norrgren L, Örn S.

Aquat Toxicol. 2018 Jul;200:93-101. doi: 10.1016/j.aquatox.2018.04.014. Epub 2018 Apr 25.

PMID:
29729477
10.

Selective concentration for ciprofloxacin resistance in Escherichia coli grown in complex aquatic bacterial biofilms.

Kraupner N, Ebmeyer S, Bengtsson-Palme J, Fick J, Kristiansson E, Flach CF, Larsson DGJ.

Environ Int. 2018 Jul;116:255-268. doi: 10.1016/j.envint.2018.04.029. Epub 2018 Apr 25.

PMID:
29704804
11.

Differential removal of human pathogenic viruses from sewage by conventional and ozone treatments.

Wang H, Sikora P, Rutgersson C, Lindh M, Brodin T, Björlenius B, Larsson DGJ, Norder H.

Int J Hyg Environ Health. 2018 Apr;221(3):479-488. doi: 10.1016/j.ijheh.2018.01.012. Epub 2018 Feb 1.

12.

Functional metagenomics reveals a novel carbapenem-hydrolyzing mobile beta-lactamase from Indian river sediments contaminated with antibiotic production waste.

Marathe NP, Janzon A, Kotsakis SD, Flach CF, Razavi M, Berglund F, Kristiansson E, Larsson DGJ.

Environ Int. 2018 Mar;112:279-286. doi: 10.1016/j.envint.2017.12.036. Epub 2018 Jan 6.

PMID:
29316517
13.

Antimicrobial resistance and the environment: assessment of advances, gaps and recommendations for agriculture, aquaculture and pharmaceutical manufacturing.

Topp E, Larsson DGJ, Miller DN, Van den Eede C, Virta MPJ.

FEMS Microbiol Ecol. 2018 Mar 1;94(3). doi: 10.1093/femsec/fix185.

PMID:
29309580
14.

Risks of using the natural defence of commensal bacteria as antibiotics call for research and regulation.

Larsson DGJ.

Int J Antimicrob Agents. 2018 Feb;51(2):277-278. doi: 10.1016/j.ijantimicag.2017.12.018. Epub 2017 Dec 25. No abstract available.

PMID:
29284154
15.

Antibiotics and common antibacterial biocides stimulate horizontal transfer of resistance at low concentrations.

Jutkina J, Marathe NP, Flach CF, Larsson DGJ.

Sci Total Environ. 2018 Mar;616-617:172-178. doi: 10.1016/j.scitotenv.2017.10.312. Epub 2017 Nov 16.

PMID:
29112840
16.

Protection goals must guide risk assessment for antibiotics.

Bengtsson-Palme J, Larsson DGJ.

Environ Int. 2018 Feb;111:352-353. doi: 10.1016/j.envint.2017.10.019. Epub 2017 Oct 31. No abstract available.

PMID:
29097053
17.

Environmental factors influencing the development and spread of antibiotic resistance.

Bengtsson-Palme J, Kristiansson E, Larsson DGJ.

FEMS Microbiol Rev. 2018 Jan 1;42(1). doi: 10.1093/femsre/fux053. Review.

18.

Identification of 76 novel B1 metallo-β-lactamases through large-scale screening of genomic and metagenomic data.

Berglund F, Marathe NP, Österlund T, Bengtsson-Palme J, Kotsakis S, Flach CF, Larsson DGJ, Kristiansson E.

Microbiome. 2017 Oct 12;5(1):134. doi: 10.1186/s40168-017-0353-8.

19.

Computational discovery and functional validation of novel fluoroquinolone resistance genes in public metagenomic data sets.

Boulund F, Berglund F, Flach CF, Bengtsson-Palme J, Marathe NP, Larsson DGJ, Kristiansson E.

BMC Genomics. 2017 Sep 2;18(1):682. doi: 10.1186/s12864-017-4064-0.

20.

Untreated urban waste contaminates Indian river sediments with resistance genes to last resort antibiotics.

Marathe NP, Pal C, Gaikwad SS, Jonsson V, Kristiansson E, Larsson DGJ.

Water Res. 2017 Nov 1;124:388-397. doi: 10.1016/j.watres.2017.07.060. Epub 2017 Jul 25.

PMID:
28780361
21.

Using metagenomics to investigate human and environmental resistomes.

Bengtsson-Palme J, Larsson DGJ, Kristiansson E.

J Antimicrob Chemother. 2017 Oct 1;72(10):2690-2703. doi: 10.1093/jac/dkx199. Review.

PMID:
28673041
22.

Diclofenac affects kidney histology in the three-spined stickleback (Gasterosteus aculeatus) at low μg/L concentrations.

Näslund J, Fick J, Asker N, Ekman E, Larsson DGJ, Norrgren L.

Aquat Toxicol. 2017 Aug;189:87-96. doi: 10.1016/j.aquatox.2017.05.017. Epub 2017 May 31.

PMID:
28601012
23.

Metal Resistance and Its Association With Antibiotic Resistance.

Pal C, Asiani K, Arya S, Rensing C, Stekel DJ, Larsson DGJ, Hobman JL.

Adv Microb Physiol. 2017;70:261-313. doi: 10.1016/bs.ampbs.2017.02.001. Epub 2017 Apr 3. Review.

PMID:
28528649
24.

Does antifouling paint select for antibiotic resistance?

Flach CF, Pal C, Svensson CJ, Kristiansson E, Östman M, Bengtsson-Palme J, Tysklind M, Larsson DGJ.

Sci Total Environ. 2017 Jul 15;590-591:461-468. doi: 10.1016/j.scitotenv.2017.01.213. Epub 2017 Mar 8.

PMID:
28284638
25.

Bacterial resistance to arsenic protects against protist killing.

Hao X, Li X, Pal C, Hobman J, Larsson DG, Saquib Q, Alwathnani HA, Rosen BP, Zhu YG, Rensing C.

Biometals. 2017 Apr;30(2):307-311. doi: 10.1007/s10534-017-0003-4. Epub 2017 Feb 16.

26.

Limited Bacterial Diversity within a Treatment Plant Receiving Antibiotic-Containing Waste from Bulk Drug Production.

Marathe NP, Shetty SA, Shouche YS, Larsson DG.

PLoS One. 2016 Nov 3;11(11):e0165914. doi: 10.1371/journal.pone.0165914. eCollection 2016.

27.

The structure and diversity of human, animal and environmental resistomes.

Pal C, Bengtsson-Palme J, Kristiansson E, Larsson DG.

Microbiome. 2016 Oct 7;4(1):54.

28.

Elucidating selection processes for antibiotic resistance in sewage treatment plants using metagenomics.

Bengtsson-Palme J, Hammarén R, Pal C, Östman M, Björlenius B, Flach CF, Fick J, Kristiansson E, Tysklind M, Larsson DGJ.

Sci Total Environ. 2016 Dec 1;572:697-712. doi: 10.1016/j.scitotenv.2016.06.228. Epub 2016 Aug 17.

PMID:
27542633
29.

Minimal selective concentrations of tetracycline in complex aquatic bacterial biofilms.

Lundström SV, Östman M, Bengtsson-Palme J, Rutgersson C, Thoudal M, Sircar T, Blanck H, Eriksson KM, Tysklind M, Flach CF, Larsson DGJ.

Sci Total Environ. 2016 May 15;553:587-595. doi: 10.1016/j.scitotenv.2016.02.103. Epub 2016 Mar 22.

PMID:
26938321
30.

Resistance Mutations in gyrA and parC are Common in Escherichia Communities of both Fluoroquinolone-Polluted and Uncontaminated Aquatic Environments.

Johnning A, Kristiansson E, Fick J, Weijdegård B, Larsson DG.

Front Microbiol. 2015 Dec 9;6:1355. doi: 10.3389/fmicb.2015.01355. eCollection 2015.

31.

Concentrations of antibiotics predicted to select for resistant bacteria: Proposed limits for environmental regulation.

Bengtsson-Palme J, Larsson DG.

Environ Int. 2016 Jan;86:140-9. doi: 10.1016/j.envint.2015.10.015. Epub 2015 Nov 17.

32.

Co-occurrence of resistance genes to antibiotics, biocides and metals reveals novel insights into their co-selection potential.

Pal C, Bengtsson-Palme J, Kristiansson E, Larsson DG.

BMC Genomics. 2015 Nov 17;16:964. doi: 10.1186/s12864-015-2153-5.

33.

Quinolone resistance mutations in the faecal microbiota of Swedish travellers to India.

Johnning A, Kristiansson E, Angelin M, Marathe N, Shouche YS, Johansson A, Larsson DG.

BMC Microbiol. 2015 Oct 24;15:235. doi: 10.1186/s12866-015-0574-6.

34.

The Human Gut Microbiome as a Transporter of Antibiotic Resistance Genes between Continents.

Bengtsson-Palme J, Angelin M, Huss M, Kjellqvist S, Kristiansson E, Palmgren H, Larsson DG, Johansson A.

Antimicrob Agents Chemother. 2015 Oct;59(10):6551-60. doi: 10.1128/AAC.00933-15. Epub 2015 Aug 10.

35.

Isolation of novel IncA/C and IncN fluoroquinolone resistance plasmids from an antibiotic-polluted lake.

Flach CF, Johnning A, Nilsson I, Smalla K, Kristiansson E, Larsson DG.

J Antimicrob Chemother. 2015 Oct;70(10):2709-17. doi: 10.1093/jac/dkv167. Epub 2015 Jun 29.

PMID:
26124213
36.

Progesterone-mediated effects on gene expression and oocyte-cumulus complex transport in the mouse fallopian tube.

Bylander A, Gunnarsson L, Shao R, Billig H, Larsson DG.

Reprod Biol Endocrinol. 2015 May 13;13:40. doi: 10.1186/s12958-015-0038-8.

37.

Antibiotic resistance genes in the environment: prioritizing risks.

Bengtsson-Palme J, Larsson DG.

Nat Rev Microbiol. 2015 Jun;13(6):396. doi: 10.1038/nrmicro3399-c1. Epub 2015 Apr 27. No abstract available.

PMID:
25915637
38.

Improving environmental risk assessment of human pharmaceuticals.

Ågerstrand M, Berg C, Björlenius B, Breitholtz M, Brunström B, Fick J, Gunnarsson L, Larsson DG, Sumpter JP, Tysklind M, Rudén C.

Environ Sci Technol. 2015 May 5;49(9):5336-45. doi: 10.1021/acs.est.5b00302. Epub 2015 Apr 16.

PMID:
25844810
39.

METAXA2: improved identification and taxonomic classification of small and large subunit rRNA in metagenomic data.

Bengtsson-Palme J, Hartmann M, Eriksson KM, Pal C, Thorell K, Larsson DG, Nilsson RH.

Mol Ecol Resour. 2015 Nov;15(6):1403-14. doi: 10.1111/1755-0998.12399. Epub 2015 Mar 23.

PMID:
25732605
40.

Waterborne beclomethasone dipropionate affects the physiology of fish while its metabolite beclomethasone is not taken up.

Carney Almroth BM, Gunnarsson LM, Cuklev F, Fick J, Kristiansson E, Larsson DG.

Sci Total Environ. 2015 Apr 1;511:37-46. doi: 10.1016/j.scitotenv.2014.12.016. Epub 2014 Dec 18.

PMID:
25527967
41.

Shotgun metagenomics reveals a wide array of antibiotic resistance genes and mobile elements in a polluted lake in India.

Bengtsson-Palme J, Boulund F, Fick J, Kristiansson E, Larsson DG.

Front Microbiol. 2014 Dec 2;5:648. doi: 10.3389/fmicb.2014.00648. eCollection 2014.

42.

Potential ecological footprints of active pharmaceutical ingredients: an examination of risk factors in low-, middle- and high-income countries.

Kookana RS, Williams M, Boxall AB, Larsson DG, Gaw S, Choi K, Yamamoto H, Thatikonda S, Zhu YG, Carriquiriborde P.

Philos Trans R Soc Lond B Biol Sci. 2014 Nov 19;369(1656). pii: 20130586. doi: 10.1098/rstb.2013.0586. Review.

43.

Pollution from drug manufacturing: review and perspectives.

Larsson DG.

Philos Trans R Soc Lond B Biol Sci. 2014 Nov 19;369(1656). pii: 20130571. doi: 10.1098/rstb.2013.0571. Review.

44.

Underappreciated role of regionally poor water quality on globally increasing antibiotic resistance.

Graham DW, Collignon P, Davies J, Larsson DG, Snape J.

Environ Sci Technol. 2014 Oct 21;48(20):11746-7. doi: 10.1021/es504206x. Epub 2014 Oct 1. No abstract available.

PMID:
25330712
45.

Aqueous and lipid nuclear magnetic resonance metabolomic profiles of the earthworm Aporrectodea caliginosa show potential as an indicator species for environmental metabolomics.

Brown JN, Samuelsson L, Bernardi G, Gooneratne R, Larsson DG.

Environ Toxicol Chem. 2014 Oct;33(10):2313-22. doi: 10.1002/etc.2680. Epub 2014 Aug 22.

PMID:
24995628
46.

Fluoroquinolones and qnr genes in sediment, water, soil, and human fecal flora in an environment polluted by manufacturing discharges.

Rutgersson C, Fick J, Marathe N, Kristiansson E, Janzon A, Angelin M, Johansson A, Shouche Y, Flach CF, Larsson DG.

Environ Sci Technol. 2014 Jul 15;48(14):7825-32. doi: 10.1021/es501452a. Epub 2014 Jul 2.

PMID:
24988042
47.

Tissue-specific bioconcentration of antidepressants in fish exposed to effluent from a municipal sewage treatment plant.

Grabicova K, Lindberg RH, Ostman M, Grabic R, Randak T, Larsson DG, Fick J.

Sci Total Environ. 2014 Aug 1;488-489:46-50. doi: 10.1016/j.scitotenv.2014.04.052. Epub 2014 May 8.

PMID:
24814035
48.

[Good drugs at the wrong place can affect nature and lead to resistance].

Larsson DG, Greko C.

Lakartidningen. 2014 Apr 2-8;111(14):619-20. Review. Swedish. No abstract available.

PMID:
24779181
49.

Antibiotics in the environment.

Larsson DG.

Ups J Med Sci. 2014 May;119(2):108-12. doi: 10.3109/03009734.2014.896438. Epub 2014 Mar 19. Review.

50.

BacMet: antibacterial biocide and metal resistance genes database.

Pal C, Bengtsson-Palme J, Rensing C, Kristiansson E, Larsson DG.

Nucleic Acids Res. 2014 Jan;42(Database issue):D737-43. doi: 10.1093/nar/gkt1252. Epub 2013 Dec 3.

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