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Initial toxicity, quality-of-life outcomes, and dosimetric impact in a randomized phase 3 trial of hypofractionated versus standard fractionated proton therapy for low-risk prostate cancer.

Vargas CE, Schmidt MQ, Niska JR, Hartsell WF, Keole SR, Doh L, Chang JH, Sinesi C, Rodriquez R, Pankuch M, Larson GL.

Adv Radiat Oncol. 2018 Feb 23;3(3):322-330. doi: 10.1016/j.adro.2018.02.004. eCollection 2018 Jul-Sep.


Model systems for analysis of dopamine transporter function and regulation.

Hovde MJ, Larson GH, Vaughan RA, Foster JD.

Neurochem Int. 2018 Sep 1. pii: S0197-0186(18)30293-6. doi: 10.1016/j.neuint.2018.08.015. [Epub ahead of print]


Proton therapy patterns of care among pediatric and adult patients with CNS tumors.

Tseng YD, Hartsell W, Tsai H, Badiyan S, Wang CJ, Rossi C, Kotecha R, Vora S, Vargas C, Larson G, Halasz LM.

Neuro Oncol. 2018 Oct 9;20(11):1556-1557. doi: 10.1093/neuonc/noy116. No abstract available.


Proteomic evidence of dietary sources in ancient dental calculus.

Hendy J, Warinner C, Bouwman A, Collins MJ, Fiddyment S, Fischer R, Hagan R, Hofman CA, Holst M, Chaves E, Klaus L, Larson G, Mackie M, McGrath K, Mundorff AZ, Radini A, Rao H, Trachsel C, Velsko IM, Speller CF.

Proc Biol Sci. 2018 Jul 18;285(1883). pii: 20180977. doi: 10.1098/rspb.2018.0977.


Selection of Appropriate Metagenome Taxonomic Classifiers for Ancient Microbiome Research.

Velsko IM, Frantz LAF, Herbig A, Larson G, Warinner C.

mSystems. 2018 Jul 17;3(4). pii: e00080-18. doi: 10.1128/mSystems.00080-18. eCollection 2018 Jul-Aug.


The evolutionary history of dogs in the Americas.

Ní Leathlobhair M, Perri AR, Irving-Pease EK, Witt KE, Linderholm A, Haile J, Lebrasseur O, Ameen C, Blick J, Boyko AR, Brace S, Cortes YN, Crockford SJ, Devault A, Dimopoulos EA, Eldridge M, Enk J, Gopalakrishnan S, Gori K, Grimes V, Guiry E, Hansen AJ, Hulme-Beaman A, Johnson J, Kitchen A, Kasparov AK, Kwon YM, Nikolskiy PA, Lope CP, Manin A, Martin T, Meyer M, Myers KN, Omura M, Rouillard JM, Pavlova EY, Sciulli P, Sinding MS, Strakova A, Ivanova VV, Widga C, Willerslev E, Pitulko VV, Barnes I, Gilbert MTP, Dobney KM, Malhi RS, Murchison EP, Larson G, Frantz LAF.

Science. 2018 Jul 6;361(6397):81-85. doi: 10.1126/science.aao4776.


Effective Assignment of α2,3/α2,6-Sialic Acid Isomers by LC-MS/MS-Based Glycoproteomics.

Pett C, Nasir W, Sihlbom C, Olsson BM, Caixeta V, Schorlemer M, Zahedi RP, Larson G, Nilsson J, Westerlind U.

Angew Chem Int Ed Engl. 2018 Jul 20;57(30):9320-9324. doi: 10.1002/anie.201803540. Epub 2018 Jun 20.


LC-MS/MS characterization of xyloside-primed glycosaminoglycans with cytotoxic properties reveals structural diversity and novel glycan modifications.

Persson A, Gomez Toledo A, Vorontsov E, Nasir W, Willén D, Noborn F, Ellervik U, Mani K, Nilsson J, Larson G.

J Biol Chem. 2018 Jun 29;293(26):10202-10219. doi: 10.1074/jbc.RA118.002971. Epub 2018 May 8.


Cracking the Sugar Code by Mass Spectrometry : An Invited Perspective in Honor of Dr. Catherine E. Costello, Recipient of the 2017 ASMS Distinguished Contribution Award.

Mirgorodskaya E, Karlsson NG, Sihlbom C, Larson G, Nilsson CL.

J Am Soc Mass Spectrom. 2018 Jun;29(6):1065-1074. doi: 10.1007/s13361-018-1912-3. Epub 2018 Apr 11.


Author Correction: FUT2 non-secretor status is associated with altered susceptibility to symptomatic enterotoxigenic Escherichia coli infection in Bangladeshis.

Mottram L, Wiklund G, Larson G, Qadri F, Svennerholm AM.

Sci Rep. 2018 Apr 11;8(1):6058. doi: 10.1038/s41598-018-22786-9.


Synchronous diversification of Sulawesi's iconic artiodactyls driven by recent geological events.

Frantz LAF, Rudzinski A, Nugraha AMS, Evin A, Burton J, Hulme-Beaman A, Linderholm A, Barnett R, Vega R, Irving-Pease EK, Haile J, Allen R, Leus K, Shephard J, Hillyer M, Gillemot S, van den Hurk J, Ogle S, Atofanei C, Thomas MG, Johansson F, Mustari AH, Williams J, Mohamad K, Damayanti CS, Wiryadi ID, Obbles D, Mona S, Day H, Yasin M, Meker S, McGuire JA, Evans BJ, von Rintelen T, Ho SYW, Searle JB, Kitchener AC, Macdonald AA, Shaw DJ, Hall R, Galbusera P, Larson G.

Proc Biol Sci. 2018 Apr 11;285(1876). pii: 20172566. doi: 10.1098/rspb.2017.2566.


Membrane Deformation Induces Clustering of Norovirus Bound to Glycosphingolipids in a Supported Cell-Membrane Mimic.

Parveen N, Rimkute I, Block S, Rydell GE, Midtvedt D, Larson G, Hytönen VP, Zhdanov VP, Lundgren A, Höök F.

J Phys Chem Lett. 2018 May 3;9(9):2278-2284. doi: 10.1021/acs.jpclett.8b00433. Epub 2018 Apr 19.


An interactive contouring module improves engagement and interest in radiation oncology among preclinical medical students: Results of a randomized trial.

Neppala P, Sherer MV, Larson G, Bryant AK, Panjwani N, Murphy JD, Gillespie EF.

Pract Radiat Oncol. 2018 Jul - Aug;8(4):e190-e198. doi: 10.1016/j.prro.2018.01.001. Epub 2018 Jan 12.


Rabbits and the Specious Origins of Domestication.

Irving-Pease EK, Frantz LAF, Sykes N, Callou C, Larson G.

Trends Ecol Evol. 2018 Mar;33(3):149-152. doi: 10.1016/j.tree.2017.12.009. Epub 2018 Feb 14.


Relationship between QTL for grain shape, grain weight, test weight, milling yield, and plant height in the spring wheat cross RL4452/'AC Domain'.

Cabral AL, Jordan MC, Larson G, Somers DJ, Humphreys DG, McCartney CA.

PLoS One. 2018 Jan 22;13(1):e0190681. doi: 10.1371/journal.pone.0190681. eCollection 2018.


Genetic basis of photosynthetic responses to cold in two locally adapted populations of Arabidopsis thaliana.

Oakley CG, Savage L, Lotz S, Larson GR, Thomashow MF, Kramer DM, Schemske DW.

J Exp Bot. 2018 Jan 23;69(3):699-709. doi: 10.1093/jxb/erx437.


Expanding the chondroitin glycoproteome of Caenorhabditis elegans.

Noborn F, Gomez Toledo A, Nasir W, Nilsson J, Dierker T, Kjellén L, Larson G.

J Biol Chem. 2018 Jan 5;293(1):379-389. doi: 10.1074/jbc.M117.807800. Epub 2017 Nov 14.


The dental calculus metabolome in modern and historic samples.

Velsko IM, Overmyer KA, Speller C, Klaus L, Collins MJ, Loe L, Frantz LAF, Sankaranarayanan K, Lewis CM Jr, Martinez JBR, Chaves E, Coon JJ, Larson G, Warinner C.

Metabolomics. 2017;13(11):134. doi: 10.1007/s11306-017-1270-3. Epub 2017 Oct 3.


Minimal toxicity after proton beam therapy for prostate and pelvic nodal irradiation: results from the proton collaborative group REG001-09 trial.

Chuong MD, Hartsell W, Larson G, Tsai H, Laramore GE, Rossi CJ, Wilkinson JB, Kaiser A, Vargas C.

Acta Oncol. 2018 Mar;57(3):368-374. doi: 10.1080/0284186X.2017.1388539. Epub 2017 Oct 14.


Proton beam reirradiation for locally recurrent pancreatic adenocarcinoma.

Boimel PJ, Berman AT, Li J, Apisarnthanarax S, Both S, Lelionis K, Larson GL, Teitelbaum U, Lukens JN, Ben-Josef E, Metz JM, Plastaras JP.

J Gastrointest Oncol. 2017 Aug;8(4):665-674. doi: 10.21037/jgo.2017.03.04.


FUT2 non-secretor status is associated with altered susceptibility to symptomatic enterotoxigenic Escherichia coli infection in Bangladeshis.

Mottram L, Wiklund G, Larson G, Qadri F, Svennerholm AM.

Sci Rep. 2017 Sep 6;7(1):10649. doi: 10.1038/s41598-017-10854-5. Erratum in: Sci Rep. 2018 Apr 11;8(1):6058.


Effects of military service and deployment on clinical symptomatology: The role of trauma exposure and social support.

Moore TM, Risbrough VB, Baker DG, Larson GE, Glenn DE, Nievergelt CM, Maihofer A, Port AM, Jackson CT, Ruparel K, Gur RC.

J Psychiatr Res. 2017 Dec;95:121-128. doi: 10.1016/j.jpsychires.2017.08.013. Epub 2017 Aug 19.


Reconstructing Asian faunal introductions to eastern Africa from multi-proxy biomolecular and archaeological datasets.

Prendergast ME, Buckley M, Crowther A, Frantz L, Eager H, Lebrasseur O, Hutterer R, Hulme-Beaman A, Van Neer W, Douka K, Veall MA, Quintana Morales EM, Schuenemann VJ, Reiter E, Allen R, Dimopoulos EA, Helm RM, Shipton C, Mwebi O, Denys C, Horton M, Wynne-Jones S, Fleisher J, Radimilahy C, Wright H, Searle JB, Krause J, Larson G, Boivin NL.

PLoS One. 2017 Aug 17;12(8):e0182565. doi: 10.1371/journal.pone.0182565. eCollection 2017. Erratum in: PLoS One. 2017 Dec 20;12 (12 ):e0190336.


A test for paedomorphism in domestic pig cranial morphology.

Evin A, Owen J, Larson G, Debiais-Thibaud M, Cucchi T, Vidarsdottir US, Dobney K.

Biol Lett. 2017 Aug;13(8). pii: 20170321. doi: 10.1098/rsbl.2017.0321.


Conventional Wisdom versus Actual Outcomes: Challenges in the Conduct of an Ebola Vaccine Trial in Liberia during the International Public Health Emergency.

Larson GS, Baseler BR, Hoover ML, Pierson JF, Tegli JK, Johnson MP, Kieh MWS, McNay LA, Njoh WS.

Am J Trop Med Hyg. 2017 Jul;97(1):10-15. doi: 10.4269/ajtmh.16-1015.


Effect of Antidepressant Switching vs Augmentation on Remission Among Patients With Major Depressive Disorder Unresponsive to Antidepressant Treatment: The VAST-D Randomized Clinical Trial.

Mohamed S, Johnson GR, Chen P, Hicks PB, Davis LL, Yoon J, Gleason TC, Vertrees JE, Weingart K, Tal I, Scrymgeour A, Lawrence DD, Planeta B, Thase ME, Huang GD, Zisook S; and the VAST-D Investigators, Rao SD, Pilkinton PD, Wilcox JA, Iranmanesh A, Sapra M, Jurjus G, Michalets JP, Aslam M, Beresford T, Anderson KD, Fernando R, Ramaswamy S, Kasckow J, Westermeyer J, Yoon G, D'Souza DC, Larson G, Anderson WG, Klatt M, Fareed A, Thompson SI, Carrera CJ, Williams SS, Juergens TM, Albers LJ, Nasdahl CS, Villarreal G, Winston JL, Nogues CA, Connolly KR, Tapp A, Jones KA, Khatkhate G, Marri S, Suppes T, LaMotte J, Hurley R, Mayeda AR, Niculescu AB 3rd, Fischer BA, Loreck DJ, Rosenlicht N, Lieske S, Finkel MS, Little JT.

JAMA. 2017 Jul 11;318(2):132-145. doi: 10.1001/jama.2017.8036.


The wolf reference genome sequence (Canis lupus lupus) and its implications for Canis spp. population genomics.

Gopalakrishnan S, Samaniego Castruita JA, Sinding MS, Kuderna LFK, Räikkönen J, Petersen B, Sicheritz-Ponten T, Larson G, Orlando L, Marques-Bonet T, Hansen AJ, Dalén L, Gilbert MTP.

BMC Genomics. 2017 Jun 29;18(1):495. doi: 10.1186/s12864-017-3883-3.


A composite window into human history.

Johannsen NN, Larson G, Meltzer DJ, Vander Linden M.

Science. 2017 Jun 16;356(6343):1118-1120. doi: 10.1126/science.aan0737. No abstract available.


Human Sera Collected between 1979 and 2010 Possess Blocking-Antibody Titers to Pandemic GII.4 Noroviruses Isolated over Three Decades.

Sharma S, Carlsson B, Czakó R, Vene S, Haglund M, Ludvigsson J, Larson G, Hammarström L, Sosnovtsev SV, Atmar RL, Green KY, Estes MK, Svensson L.

J Virol. 2017 Jun 26;91(14). pii: e00567-17. doi: 10.1128/JVI.00567-17. Print 2017 Jul 15.


Inferring Allele Frequency Trajectories from Ancient DNA Indicates That Selection on a Chicken Gene Coincided with Changes in Medieval Husbandry Practices.

Loog L, Thomas MG, Barnett R, Allen R, Sykes N, Paxinos PD, Lebrasseur O, Dobney K, Peters J, Manica A, Larson G, Eriksson A.

Mol Biol Evol. 2017 Aug 1;34(8):1981-1990. doi: 10.1093/molbev/msx142.


Histo-Blood Group Antigen Presentation Is Critical for Binding of Norovirus VLP to Glycosphingolipids in Model Membranes.

Nasir W, Frank M, Kunze A, Bally M, Parra F, Nyholm PG, Höök F, Larson G.

ACS Chem Biol. 2017 May 19;12(5):1288-1296. doi: 10.1021/acschembio.7b00152. Epub 2017 Mar 27.


Multi-institutional Randomized Trial Testing the Utility of an Interactive Three-dimensional Contouring Atlas Among Radiation Oncology Residents.

Gillespie EF, Panjwani N, Golden DW, Gunther J, Chapman TR, Brower JV, Kosztyla R, Larson G, Neppala P, Moiseenko V, Bykowski J, Sanghvi P, Murphy JD.

Int J Radiat Oncol Biol Phys. 2017 Jul 1;98(3):547-554. doi: 10.1016/j.ijrobp.2016.11.050. Epub 2016 Dec 9.


Origin and phylogenetic status of the local Ashanti Dwarf pig (ADP) of Ghana based on genetic analysis.

Osei-Amponsah R, Skinner BM, Adjei DO, Bauer J, Larson G, Affara NA, Sargent CA.

BMC Genomics. 2017 Feb 20;18(1):193. doi: 10.1186/s12864-017-3536-6.


A genetic risk factor for major depression and suicidal ideation is mitigated by physical activity.

Taylor MK, Beckerley SE, Henniger NE, Hernández LM, Larson GE, Granger DA.

Psychiatry Res. 2017 Mar;249:304-306. doi: 10.1016/j.psychres.2017.01.002. Epub 2017 Jan 20.


Characterization of Glycan Structures of Chondroitin Sulfate-Glycopeptides Facilitated by Sodium Ion-Pairing and Positive Mode LC-MS/MS.

Nilsson J, Noborn F, Gomez Toledo A, Nasir W, Sihlbom C, Larson G.

J Am Soc Mass Spectrom. 2017 Feb;28(2):229-241. doi: 10.1007/s13361-016-1539-1. Epub 2016 Nov 21.


Taming the Past: Ancient DNA and the Study of Animal Domestication.

MacHugh DE, Larson G, Orlando L.

Annu Rev Anim Biosci. 2017 Feb 8;5:329-351. doi: 10.1146/annurev-animal-022516-022747. Epub 2016 Oct 28. Review.


Early cave art and ancient DNA record the origin of European bison.

Soubrier J, Gower G, Chen K, Richards SM, Llamas B, Mitchell KJ, Ho SY, Kosintsev P, Lee MS, Baryshnikov G, Bollongino R, Bover P, Burger J, Chivall D, Crégut-Bonnoure E, Decker JE, Doronichev VB, Douka K, Fordham DA, Fontana F, Fritz C, Glimmerveen J, Golovanova LV, Groves C, Guerreschi A, Haak W, Higham T, Hofman-Kamińska E, Immel A, Julien MA, Krause J, Krotova O, Langbein F, Larson G, Rohrlach A, Scheu A, Schnabel RD, Taylor JF, Tokarska M, Tosello G, van der Plicht J, van Loenen A, Vigne JD, Wooley O, Orlando L, Kowalczyk R, Shapiro B, Cooper A.

Nat Commun. 2016 Oct 18;7:13158. doi: 10.1038/ncomms13158.


Dosimetric and radiobiological impact of intensity modulated proton therapy and RapidArc planning for high-risk prostate cancer with seminal vesicles.

Rana S, Cheng C, Zhao L, Park S, Larson G, Vargas C, Dunn M, Zheng Y.

J Med Radiat Sci. 2017 Mar;64(1):18-24. doi: 10.1002/jmrs.175. Epub 2016 May 11.


A novel MC1R allele for black coat colour reveals the Polynesian ancestry and hybridization patterns of Hawaiian feral pigs.

Linderholm A, Spencer D, Battista V, Frantz L, Barnett R, Fleischer RC, James HF, Duffy D, Sparks JP, Clements DR, Andersson L, Dobney K, Leonard JA, Larson G.

R Soc Open Sci. 2016 Sep 7;3(9):160304. eCollection 2016 Sep.


Site-specific identification of heparan and chondroitin sulfate glycosaminoglycans in hybrid proteoglycans.

Noborn F, Gomez Toledo A, Green A, Nasir W, Sihlbom C, Nilsson J, Larson G.

Sci Rep. 2016 Oct 3;6:34537. doi: 10.1038/srep34537.


Low Levels of Acute Toxicity Associated With Proton Therapy for Low-Grade Glioma: A Proton Collaborative Group Study.

Wilkinson B, Morgan H, Gondi V, Larson GL, Hartsell WF, Laramore GE, Halasz LM, Vargas C, Keole SR, Grosshans DR, Shih HA, Mehta MP.

Int J Radiat Oncol Biol Phys. 2016 Oct 1;96(2S):E135. doi: 10.1016/j.ijrobp.2016.06.930. No abstract available.


Image-guided hypofractionated proton beam therapy for low-risk prostate cancer: Analysis of quality of life and toxicity, PCG GU 002.

Vargas CE, Hartsell WF, Dunn M, Keole SR, Doh L, Chang J, Larson GL.

Rep Pract Oncol Radiother. 2016 May-Jun;21(3):207-12. doi: 10.1016/j.rpor.2016.01.002. Epub 2016 Mar 4.


Proton therapy patterns-of-care and early outcomes for Hodgkin lymphoma: results from the Proton Collaborative Group Registry.

Hoppe BS, Tsai H, Larson G, Laramore GE, Vargas C, Tseng YD, Dunn M, McGee L, Cahlon O, Hartsell W.

Acta Oncol. 2016 Nov;55(11):1378-1380. Epub 2016 Aug 31. No abstract available.


Reply to Westaway and Lyman: Emus, dingoes, and archaeology's role in conservation biology.

Zeder MA, Denham T, Erlandson JM, Boivin NL, Crowther A, Fuller DQ, Larson G, Petraglia MD.

Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):E4759-60. doi: 10.1073/pnas.1610697113. Epub 2016 Jul 26. No abstract available.


Reply to Ellis et al.: Human niche construction and evolutionary theory.

Erlandson JM, Zeder MA, Boivin NL, Crowther A, Denham T, Fuller DQ, Larson G, Petraglia MD.

Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):E4437-8. doi: 10.1073/pnas.1609617113. Epub 2016 Jul 15. No abstract available.


SweetNET: A Bioinformatics Workflow for Glycopeptide MS/MS Spectral Analysis.

Nasir W, Toledo AG, Noborn F, Nilsson J, Wang M, Bandeira N, Larson G.

J Proteome Res. 2016 Aug 5;15(8):2826-40. doi: 10.1021/acs.jproteome.6b00417. Epub 2016 Jul 27.


Minimizing treatment planning errors in proton therapy using failure mode and effects analysis.

Zheng Y, Johnson R, Larson G.

Med Phys. 2016 Jun;43(6):2904-2910. doi: 10.1118/1.4948686.


Ecological consequences of human niche construction: Examining long-term anthropogenic shaping of global species distributions.

Boivin NL, Zeder MA, Fuller DQ, Crowther A, Larson G, Erlandson JM, Denham T, Petraglia MD.

Proc Natl Acad Sci U S A. 2016 Jun 7;113(23):6388-96. doi: 10.1073/pnas.1525200113.


Genomic and archaeological evidence suggest a dual origin of domestic dogs.

Frantz LA, Mullin VE, Pionnier-Capitan M, Lebrasseur O, Ollivier M, Perri A, Linderholm A, Mattiangeli V, Teasdale MD, Dimopoulos EA, Tresset A, Duffraisse M, McCormick F, Bartosiewicz L, Gál E, Nyerges ÉA, Sablin MV, Bréhard S, Mashkour M, Bălăşescu A, Gillet B, Hughes S, Chassaing O, Hitte C, Vigne JD, Dobney K, Hänni C, Bradley DG, Larson G.

Science. 2016 Jun 3;352(6290):1228-31. doi: 10.1126/science.aaf3161. Epub 2016 Jun 2.

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