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Items: 1 to 50 of 188

1.

Perturbations in RhoA signalling cause altered migration and impaired neuritogenesis in human iPSC-derived neural cells with PARK2 mutation.

Bogetofte H, Jensen P, Okarmus J, Schmidt SI, Agger M, Ryding M, Nørregaard P, Fenger C, Zeng X, Graakjær J, Ryan BJ, Wade-Martins R, Larsen MR, Meyer M.

Neurobiol Dis. 2019 Aug 21;132:104581. doi: 10.1016/j.nbd.2019.104581. [Epub ahead of print]

2.

Proteomics insights into the responses of Saccharomyces cerevisiae during mixed-culture alcoholic fermentation with Lachancea thermotolerans.

Peng C, Andersen B, Arshid S, Larsen MR, Albergaria H, Lametsch R, Arneborg N.

FEMS Microbiol Ecol. 2019 Sep 1;95(9). pii: fiz126. doi: 10.1093/femsec/fiz126.

PMID:
31418786
3.

PARK2 Mutation Causes Metabolic Disturbances and Impaired Survival of Human iPSC-Derived Neurons.

Bogetofte H, Jensen P, Ryding M, Schmidt SI, Okarmus J, Ritter L, Worm CS, Hohnholt MC, Azevedo C, Roybon L, Bak LK, Waagepetersen H, Ryan BJ, Wade-Martins R, Larsen MR, Meyer M.

Front Cell Neurosci. 2019 Jul 5;13:297. doi: 10.3389/fncel.2019.00297. eCollection 2019.

4.

A Systems-level Characterization of the Differentiation of Human Embryonic Stem Cells into Mesenchymal Stem Cells.

Billing AM, Dib SS, Bhagwat AM, da Silva IT, Drummond RD, Hayat S, Al-Mismar R, Ben-Hamidane H, Goswami N, Engholm-Keller K, Larsen MR, Suhre K, Rafii A, Graumann J.

Mol Cell Proteomics. 2019 Oct;18(10):1950-1966. doi: 10.1074/mcp.RA119.001356. Epub 2019 Jul 22.

PMID:
31332097
5.

Proteomic Analysis of Restored Insulin Production and Trafficking in Obese Diabetic Mouse Pancreatic Islets Following Euglycemia.

Kang T, Boland BB, Alarcon C, Grimsby JS, Rhodes CJ, Larsen MR.

J Proteome Res. 2019 Sep 6;18(9):3245-3258. doi: 10.1021/acs.jproteome.9b00160. Epub 2019 Jul 31.

PMID:
31317746
6.

Proteomic signatures of neuroinflammation in Alzheimer's disease, multiple sclerosis and ischemic stroke.

Thygesen C, Larsen MR, Finsen B.

Expert Rev Proteomics. 2019 Jul;16(7):601-611. doi: 10.1080/14789450.2019.1633919. Epub 2019 Jul 8.

PMID:
31220951
7.

Zika Virus Impairs Neurogenesis and Synaptogenesis Pathways in Human Neural Stem Cells and Neurons.

Rosa-Fernandes L, Cugola FR, Russo FB, Kawahara R, de Melo Freire CC, Leite PEC, Bassi Stern AC, Angeli CB, de Oliveira DBL, Melo SR, Zanotto PMA, Durigon EL, Larsen MR, Beltrão-Braga PCB, Palmisano G.

Front Cell Neurosci. 2019 Mar 15;13:64. doi: 10.3389/fncel.2019.00064. eCollection 2019.

8.

First-trimester proteomic profiling identifies novel predictors of gestational diabetes mellitus.

Ravnsborg T, Svaneklink S, Andersen LLT, Larsen MR, Jensen DM, Overgaard M.

PLoS One. 2019 Mar 27;14(3):e0214457. doi: 10.1371/journal.pone.0214457. eCollection 2019.

9.

Diverse Protein Profiles in CNS Myeloid Cells and CNS Tissue From Lipopolysaccharide- and Vehicle-Injected APPSWE/PS1ΔE9 Transgenic Mice Implicate Cathepsin Z in Alzheimer's Disease.

Thygesen C, Ilkjær L, Kempf SJ, Hemdrup AL, von Linstow CU, Babcock AA, Darvesh S, Larsen MR, Finsen B.

Front Cell Neurosci. 2018 Nov 6;12:397. doi: 10.3389/fncel.2018.00397. eCollection 2018.

10.

Author Correction: Snake Venom Extracellular vesicles (SVEVs) reveal wide molecular and functional proteome diversity.

Carregari VC, Rosa-Fernandes L, Baldasso P, Bydlowski SP, Marangoni S, Larsen MR, Palmisano G.

Sci Rep. 2018 Oct 23;8(1):15908. doi: 10.1038/s41598-018-33284-3.

11.

Integrated Proteomics Reveals Apoptosis-related Mechanisms Associated with Placental Malaria.

Kawahara R, Rosa-Fernandes L, Dos Santos AF, Bandeira CL, Dombrowski JG, Souza RM, Da Fonseca MP, Festuccia WT, Labriola L, Larsen MR, Marinho CRF, Palmisano G.

Mol Cell Proteomics. 2019 Feb;18(2):182-199. doi: 10.1074/mcp.RA118.000907. Epub 2018 Sep 21.

PMID:
30242111
12.

Distinct urinary glycoprotein signatures in prostate cancer patients.

Kawahara R, Ortega F, Rosa-Fernandes L, Guimarães V, Quina D, Nahas W, Schwämmle V, Srougi M, Leite KRM, Thaysen-Andersen M, Larsen MR, Palmisano G.

Oncotarget. 2018 Sep 4;9(69):33077-33097. doi: 10.18632/oncotarget.26005. eCollection 2018 Sep 4.

13.

Proteomic Profiling of Mouse Epididymosomes Reveals their Contributions to Post-testicular Sperm Maturation.

Nixon B, De Iuliis GN, Hart HM, Zhou W, Mathe A, Bernstein IR, Anderson AL, Stanger SJ, Skerrett-Byrne DA, Jamaluddin MFB, Almazi JG, Bromfield EG, Larsen MR, Dun MD.

Mol Cell Proteomics. 2019 Mar 15;18(Suppl 1):S91-S108. doi: 10.1074/mcp.RA118.000946. Epub 2018 Sep 13.

14.

Orthologous proteins of experimental de- and remyelination are differentially regulated in the CSF proteome of multiple sclerosis subtypes.

Martin NA, Nawrocki A, Molnar V, Elkjaer ML, Thygesen EK, Palkovits M, Acs P, Sejbaek T, Nielsen HH, Hegedus Z, Sellebjerg F, Molnar T, Barbosa EGV, Alcaraz N, Gallyas F Jr, Svenningsen AF, Baumbach J, Lassmann H, Larsen MR, Illes Z.

PLoS One. 2018 Aug 16;13(8):e0202530. doi: 10.1371/journal.pone.0202530. eCollection 2018.

15.

Snake Venom Extracellular vesicles (SVEVs) reveal wide molecular and functional proteome diversity.

Carregari VC, Rosa-Fernandes L, Baldasso P, Bydlowski SP, Marangoni S, Larsen MR, Palmisano G.

Sci Rep. 2018 Aug 13;8(1):12067. doi: 10.1038/s41598-018-30578-4. Erratum in: Sci Rep. 2018 Oct 23;8(1):15908.

16.
17.

Quantitative Proteomics and Phosphoproteomics Analysis Revealed Different Regulatory Mechanisms of Halothane and Rendement Napole Genes in Porcine Muscle Metabolism.

Huang H, Scheffler TL, Gerrard DE, Larsen MR, Lametsch R.

J Proteome Res. 2018 Aug 3;17(8):2834-2849. doi: 10.1021/acs.jproteome.8b00294. Epub 2018 Jun 29.

PMID:
29916714
18.

Extracellular vesicles with altered tetraspanin CD9 and CD151 levels confer increased prostate cell motility and invasion.

Brzozowski JS, Bond DR, Jankowski H, Goldie BJ, Burchell R, Naudin C, Smith ND, Scarlett CJ, Larsen MR, Dun MD, Skelding KA, Weidenhofer J.

Sci Rep. 2018 Jun 11;8(1):8822. doi: 10.1038/s41598-018-27180-z.

19.

NS1 codon usage adaptation to humans in pandemic Zika virus.

Freire CCM, Palmisano G, Braconi CT, Cugola FR, Russo FB, Beltrão-Braga PC, Iamarino A, Lima Neto DF, Sall AA, Rosa-Fernandes L, Larsen MR, Zanotto PMA.

Mem Inst Oswaldo Cruz. 2018 May 10;113(5):e170385. doi: 10.1590/0074-02760170385.

20.

Omics-Based Approach Reveals Complement-Mediated Inflammation in Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids (CLIPPERS).

Blaabjerg M, Hemdrup AL, Drici L, Ruprecht K, Garred P, Höftberger R, Kristensen BW, Kondziella D, Sejbaek T, Hansen SW, Nielsen HH, Jensen P, Meyer M, Paul F, Lassmann H, Larsen MR, Illes Z.

Front Immunol. 2018 Apr 23;9:741. doi: 10.3389/fimmu.2018.00741. eCollection 2018.

21.

SILAC-based phosphoproteomics reveals new PP2A-Cdc55-regulated processes in budding yeast.

Baro B, Játiva S, Calabria I, Vinaixa J, Bech-Serra JJ, de LaTorre C, Rodrigues J, Hernáez ML, Gil C, Barceló-Batllori S, Larsen MR, Queralt E.

Gigascience. 2018 May 1;7(5). doi: 10.1093/gigascience/giy047.

22.

Development of a Trypanosoma cruzi strain typing assay using MS2 peptide spectral libraries (Tc-STAMS2).

de Oliveira GS, Kawahara R, Rosa-Fernandes L, Mule SN, Avila CC, Teixeira MMG, Larsen MR, Palmisano G.

PLoS Negl Trop Dis. 2018 Apr 2;12(4):e0006351. doi: 10.1371/journal.pntd.0006351. eCollection 2018 Apr.

23.

A Targeted LC-MS Strategy for Low-Abundant HLA Class-I-Presented Peptide Detection Identifies Novel Human Papillomavirus T-Cell Epitopes.

Blatnik R, Mohan N, Bonsack M, Falkenby LG, Hoppe S, Josef K, Steinbach A, Becker S, Nadler WM, Rucevic M, Larsen MR, Salek M, Riemer AB.

Proteomics. 2018 Jun;18(11):e1700390. doi: 10.1002/pmic.201700390. Epub 2018 May 2.

24.

Experimental Demyelination and Axonal Loss Are Reduced in MicroRNA-146a Deficient Mice.

Martin NA, Molnar V, Szilagyi GT, Elkjaer ML, Nawrocki A, Okarmus J, Wlodarczyk A, Thygesen EK, Palkovits M, Gallyas F Jr, Larsen MR, Lassmann H, Benedikz E, Owens T, Svenningsen AF, Illes Z.

Front Immunol. 2018 Mar 12;9:490. doi: 10.3389/fimmu.2018.00490. eCollection 2018.

25.

Dynamic Changes in the Protein Localization in the Nuclear Environment in Pancreatic β-Cell after Brief Glucose Stimulation.

Kang T, Jensen P, Solovyeva V, Brewer JR, Larsen MR.

J Proteome Res. 2018 Apr 6;17(4):1664-1676. doi: 10.1021/acs.jproteome.7b00930. Epub 2018 Mar 15.

PMID:
29518335
26.

Development of a Neo-Epitope Specific Assay for Serological Assessment of Type VII Collagen Turnover and Its Relevance in Fibroproliferative Disorders.

Sand JMB, Lamy P, Juhl P, Siebuhr AS, Iversen LV, Nawrocki A, Larsen MR, Domsic RT, Franchimont N, Chavez J, Karsdal MA, Leeming DJ.

Assay Drug Dev Technol. 2018 Feb/Mar;16(2):123-131. doi: 10.1089/adt.2017.820. Epub 2018 Mar 1.

PMID:
29493258
27.

How many human proteoforms are there?

Aebersold R, Agar JN, Amster IJ, Baker MS, Bertozzi CR, Boja ES, Costello CE, Cravatt BF, Fenselau C, Garcia BA, Ge Y, Gunawardena J, Hendrickson RC, Hergenrother PJ, Huber CG, Ivanov AR, Jensen ON, Jewett MC, Kelleher NL, Kiessling LL, Krogan NJ, Larsen MR, Loo JA, Ogorzalek Loo RR, Lundberg E, MacCoss MJ, Mallick P, Mootha VK, Mrksich M, Muir TW, Patrie SM, Pesavento JJ, Pitteri SJ, Rodriguez H, Saghatelian A, Sandoval W, Schlüter H, Sechi S, Slavoff SA, Smith LM, Snyder MP, Thomas PM, Uhlén M, Van Eyk JE, Vidal M, Walt DR, White FM, Williams ER, Wohlschlager T, Wysocki VH, Yates NA, Young NL, Zhang B.

Nat Chem Biol. 2018 Feb 14;14(3):206-214. doi: 10.1038/nchembio.2576.

28.

Characterizing disease-associated changes in post-translational modifications by mass spectrometry.

Thygesen C, Boll I, Finsen B, Modzel M, Larsen MR.

Expert Rev Proteomics. 2018 Mar;15(3):245-258. doi: 10.1080/14789450.2018.1433036. Epub 2018 Feb 1. Review.

PMID:
29376447
29.

Characterization of Macrophage Endogenous S-Nitrosoproteome Using a Cysteine-Specific Phosphonate Adaptable Tag in Combination with TiO2 Chromatography.

Ibáñez-Vea M, Huang H, Martínez de Morentin X, Pérez E, Gato M, Zuazo M, Arasanz H, Fernández-Irigoyen J, Santamaría E, Fernandez-Hinojal G, Larsen MR, Escors D, Kochan G.

J Proteome Res. 2018 Mar 2;17(3):1172-1182. doi: 10.1021/acs.jproteome.7b00812. Epub 2018 Jan 25.

PMID:
29338241
30.

Characterization of the Molecular Mechanisms Underlying Glucose Stimulated Insulin Secretion from Isolated Pancreatic β-cells Using Post-translational Modification Specific Proteomics (PTMomics).

Kang T, Jensen P, Huang H, Lund Christensen G, Billestrup N, Larsen MR.

Mol Cell Proteomics. 2018 Jan;17(1):95-110. doi: 10.1074/mcp.RA117.000217. Epub 2017 Nov 7.

31.

TNFα affects CREB-mediated neuroprotective signaling pathways of synaptic plasticity in neurons as revealed by proteomics and phospho-proteomics.

Jensen P, Myhre CL, Lassen PS, Metaxas A, Khan AM, Lambertsen KL, Babcock AA, Finsen B, Larsen MR, Kempf SJ.

Oncotarget. 2017 Jul 21;8(36):60223-60242. doi: 10.18632/oncotarget.19428. eCollection 2017 Sep 1.

32.

Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer.

Jacobsen K, Bertran-Alamillo J, Molina MA, Teixidó C, Karachaliou N, Pedersen MH, Castellví J, Garzón M, Codony-Servat C, Codony-Servat J, Giménez-Capitán A, Drozdowskyj A, Viteri S, Larsen MR, Lassen U, Felip E, Bivona TG, Ditzel HJ, Rosell R.

Nat Commun. 2017 Sep 4;8(1):410. doi: 10.1038/s41467-017-00450-6.

33.

Proteomic Expression Changes in Large Cerebral Arteries After Experimental Subarachnoid Hemorrhage in Rat Are Regulated by the MEK-ERK1/2 Pathway.

Müller AH, Edwards AVG, Larsen MR, Nielsen J, Warfvinge K, Povlsen GK, Edvinsson L.

J Mol Neurosci. 2017 Aug;62(3-4):380-394. doi: 10.1007/s12031-017-0944-7. Epub 2017 Jul 24.

34.

Elucidation of Altered Pathways in Tumor-Initiating Cells of Triple-Negative Breast Cancer: A Useful Cell Model System for Drug Screening.

Christensen AG, Ehmsen S, Terp MG, Batra R, Alcaraz N, Baumbach J, Noer JB, Moreira J, Leth-Larsen R, Larsen MR, Ditzel HJ.

Stem Cells. 2017 Aug;35(8):1898-1912. doi: 10.1002/stem.2654. Epub 2017 Jun 23.

35.
36.

Understanding Alzheimer's disease by global quantification of protein phosphorylation and sialylated N-linked glycosylation profiles: A chance for new biomarkers in neuroproteomics?

Lassen PS, Thygesen C, Larsen MR, Kempf SJ.

J Proteomics. 2017 May 24;161:11-25. doi: 10.1016/j.jprot.2017.04.003. Epub 2017 Apr 8. Review.

PMID:
28396268
37.

Alterations in the Cerebral Microvascular Proteome Expression Profile After Transient Global Cerebral Ischemia in Rat.

Spray S, Johansson SE, Edwards AV, Larsen MR, Radziwon-Balicka A, Povlsen GK, Edvinsson L.

J Mol Neurosci. 2017 Mar;61(3):396-411. doi: 10.1007/s12031-016-0875-8. Epub 2016 Dec 8.

PMID:
27933490
38.

The Arrhythmogenic Calmodulin Mutation D129G Dysregulates Cell Growth, Calmodulin-dependent Kinase II Activity, and Cardiac Function in Zebrafish.

Berchtold MW, Zacharias T, Kulej K, Wang K, Torggler R, Jespersen T, Chen JN, Larsen MR, la Cour JM.

J Biol Chem. 2016 Dec 23;291(52):26636-26646. doi: 10.1074/jbc.M116.758680. Epub 2016 Nov 4.

39.

CRISPR/Cas9-mediated mutation revealed cytoplasmic tail is dispensable for IZUMO1 function and male fertility.

Young SA, Miyata H, Satouh Y, Muto M, Larsen MR, Aitken RJ, Baker MA, Ikawa M.

Reproduction. 2016 Dec;152(6):665-672. Epub 2016 Sep 13.

PMID:
27624483
40.

Chronic low-dose-rate ionising radiation affects the hippocampal phosphoproteome in the ApoE-/- Alzheimer's mouse model.

Kempf SJ, Janik D, Barjaktarovic Z, Braga-Tanaka I 3rd, Tanaka S, Neff F, Saran A, Larsen MR, Tapio S.

Oncotarget. 2016 Nov 1;7(44):71817-71832. doi: 10.18632/oncotarget.12376.

41.

A novel mass spectrometric strategy "BEMAP" reveals Extensive O-linked protein glycosylation in Enterotoxigenic Escherichia coli.

Boysen A, Palmisano G, Krogh TJ, Duggin IG, Larsen MR, Møller-Jensen J.

Sci Rep. 2016 Aug 26;6:32016. doi: 10.1038/srep32016.

42.

Comprehensive glycoprofiling of the epimastigote and trypomastigote stages of Trypanosoma cruzi.

Alves MJ, Kawahara R, Viner R, Colli W, Mattos EC, Thaysen-Andersen M, Larsen MR, Palmisano G.

J Proteomics. 2017 Jan 16;151:182-192. doi: 10.1016/j.jprot.2016.05.034. Epub 2016 Jun 16.

PMID:
27318177
43.

Simultaneous Enrichment of Cysteine-containing Peptides and Phosphopeptides Using a Cysteine-specific Phosphonate Adaptable Tag (CysPAT) in Combination with titanium dioxide (TiO2) Chromatography.

Huang H, Haar Petersen M, Ibañez-Vea M, Lassen PS, Larsen MR, Palmisano G.

Mol Cell Proteomics. 2016 Oct;15(10):3282-3296. Epub 2016 Jun 8.

44.

The Splicing Efficiency of Activating HRAS Mutations Can Determine Costello Syndrome Phenotype and Frequency in Cancer.

Hartung AM, Swensen J, Uriz IE, Lapin M, Kristjansdottir K, Petersen US, Bang JM, Guerra B, Andersen HS, Dobrowolski SF, Carey JC, Yu P, Vaughn C, Calhoun A, Larsen MR, Dyrskjøt L, Stevenson DA, Andresen BS.

PLoS Genet. 2016 May 19;12(5):e1006039. doi: 10.1371/journal.pgen.1006039. eCollection 2016 May.

45.

An integrated proteomics approach shows synaptic plasticity changes in an APP/PS1 Alzheimer's mouse model.

Kempf SJ, Metaxas A, Ibáñez-Vea M, Darvesh S, Finsen B, Larsen MR.

Oncotarget. 2016 Jun 7;7(23):33627-48. doi: 10.18632/oncotarget.9092.

46.

Glycomic and sialoproteomic data of gastric carcinoma cells overexpressing ST3GAL4.

Mereiter S, Magalhães A, Adamczyk B, Jin C, Almeida A, Drici L, Ibáñez-Vea M, Larsen MR, Kolarich D, Karlsson NG, Reis CA.

Data Brief. 2016 Mar 14;7:814-33. doi: 10.1016/j.dib.2016.03.022. eCollection 2016 Jun.

47.

Proteomic Identification of Putative MicroRNA394 Target Genes in Arabidopsis thaliana Identifies Major Latex Protein Family Members Critical for Normal Development.

Litholdo CG Jr, Parker BL, Eamens AL, Larsen MR, Cordwell SJ, Waterhouse PM.

Mol Cell Proteomics. 2016 Jun;15(6):2033-47. doi: 10.1074/mcp.M115.053124. Epub 2016 Apr 11.

48.

High-performance hybrid Orbitrap mass spectrometers for quantitative proteome analysis: Observations and implications.

Williamson JC, Edwards AV, Verano-Braga T, Schwämmle V, Kjeldsen F, Jensen ON, Larsen MR.

Proteomics. 2016 Mar;16(6):907-14. doi: 10.1002/pmic.201400545. Epub 2016 Mar 1.

PMID:
26791339
49.

Glycomic analysis of gastric carcinoma cells discloses glycans as modulators of RON receptor tyrosine kinase activation in cancer.

Mereiter S, Magalhães A, Adamczyk B, Jin C, Almeida A, Drici L, Ibáñez-Vea M, Gomes C, Ferreira JA, Afonso LP, Santos LL, Larsen MR, Kolarich D, Karlsson NG, Reis CA.

Biochim Biophys Acta. 2016 Aug;1860(8):1795-808. doi: 10.1016/j.bbagen.2015.12.016. Epub 2015 Dec 22.

PMID:
26721331
50.

Improving the Phosphoproteome Coverage for Limited Sample Amounts Using TiO2-SIMAC-HILIC (TiSH) Phosphopeptide Enrichment and Fractionation.

Engholm-Keller K, Larsen MR.

Methods Mol Biol. 2016;1355:161-77. doi: 10.1007/978-1-4939-3049-4_11.

PMID:
26584925

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