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The effect of inulin and resistant maltodextrin on weight loss during energy restriction: a randomised, placebo-controlled, double-blinded intervention.

Hess AL, Benítez-Páez A, Blædel T, Larsen LH, Iglesias JR, Madera C, Sanz Y, Larsen TM; MyNewGut Consortium.

Eur J Nutr. 2019 Oct 11. doi: 10.1007/s00394-019-02099-x. [Epub ahead of print]


Impact on Clinical Decision Making of Next-Generation Sequencing in Pediatric Epilepsy in a Tertiary Epilepsy Referral Center.

Hoelz H, Herdl C, Gerstl L, Tacke M, Vill K, von Stuelpnagel C, Rost I, Hoertnagel K, Abicht A, Hollizeck S, Larsen LHG, Borggraefe I.

Clin EEG Neurosci. 2019 Sep 25:1550059419876518. doi: 10.1177/1550059419876518. [Epub ahead of print]


Pretreatment Prevotella-to-Bacteroides ratio and markers of glucose metabolism as prognostic markers for dietary weight loss maintenance.

Hjorth MF, Christensen L, Kjølbæk L, Larsen LH, Roager HM, Kiilerich P, Kristiansen K, Astrup A.

Eur J Clin Nutr. 2019 Jul 8. doi: 10.1038/s41430-019-0466-1. [Epub ahead of print]


A Multi-omics Approach to Unraveling the Microbiome-Mediated Effects of Arabinoxylan Oligosaccharides in Overweight Humans.

Benítez-Páez A, Kjølbæk L, Gómez Del Pulgar EM, Brahe LK, Astrup A, Matysik S, Schött HF, Krautbauer S, Liebisch G, Boberska J, Claus S, Rampelli S, Brigidi P, Larsen LH, Sanz Y.

mSystems. 2019 May 28;4(4). pii: e00209-19. doi: 10.1128/mSystems.00209-19.


Parental mosaicism in epilepsies due to alleged de novo variants.

Møller RS, Liebmann N, Larsen LHG, Stiller M, Hentschel J, Kako N, Abdin D, Di Donato N, Pal DK, Zacher P, Syrbe S, Dahl HA, Lemke JR.

Epilepsia. 2019 Jun;60(6):e63-e66. doi: 10.1111/epi.15187. Epub 2019 May 11.


PIGT-CDG, a disorder of the glycosylphosphatidylinositol anchor: description of 13 novel patients and expansion of the clinical characteristics.

Bayat A, Knaus A, Juul AW, Dukic D, Gardella E, Charzewska A, Clement E, Hjalgrim H, Hoffman-Zacharska D, Horn D, Horton R, Hurst JA, Josifova D, Larsen LHG, Lascelles K, Obersztyn E, Pagnamenta A, Pal DK, Pendziwiat M, Ryten M, Taylor J, Vogt J, Weber Y, Krawitz PM, Helbig I, Kini U, Møller RS; DDD Study Group.

Genet Med. 2019 Oct;21(10):2216-2223. doi: 10.1038/s41436-019-0512-3. Epub 2019 Apr 12.


Arabinoxylan oligosaccharides and polyunsaturated fatty acid effects on gut microbiota and metabolic markers in overweight individuals with signs of metabolic syndrome: A randomized cross-over trial.

Kjølbæk L, Benítez-Páez A, Gómez Del Pulgar EM, Brahe LK, Liebisch G, Matysik S, Rampelli S, Vermeiren J, Brigidi P, Larsen LH, Astrup A, Sanz Y.

Clin Nutr. 2019 Feb 19. pii: S0261-5614(19)30030-5. doi: 10.1016/j.clnu.2019.01.012. [Epub ahead of print]


Mesial Temporal Sclerosis in SCN1A-Related Epilepsy: Two Long-Term EEG Case Studies.

Tiefes AM, Hartlieb T, Tacke M, von Stülpnagel-Steinbeis C, Larsen LHG, Hao Q, Dahl HA, Neubauer BA, Gerstl L, Kudernatsch M, Kluger GJ, Borggraefe I.

Clin EEG Neurosci. 2019 Jul;50(4):267-272. doi: 10.1177/1550059418794347. Epub 2018 Aug 17.


Diabetes, myometrium, and mitochondria in pregnant women at term.

Gam CMBF, Mortensen OH, Larsen LH, Poulsen SS, Qvortrup K, Mathiesen ER, Damm P, Quistorff B.

Acta Diabetol. 2018 Oct;55(10):999-1010. doi: 10.1007/s00592-018-1171-6. Epub 2018 Jun 21.


Prevotella-to-Bacteroides ratio predicts body weight and fat loss success on 24-week diets varying in macronutrient composition and dietary fiber: results from a post-hoc analysis.

Hjorth MF, Blædel T, Bendtsen LQ, Lorenzen JK, Holm JB, Kiilerich P, Roager HM, Kristiansen K, Larsen LH, Astrup A.

Int J Obes (Lond). 2019 Jan;43(1):149-157. doi: 10.1038/s41366-018-0093-2. Epub 2018 May 17.


Incorporating epilepsy genetics into clinical practice: a 360°evaluation.

Oates S, Tang S, Rosch R, Lear R, Hughes EF, Williams RE, Larsen LHG, Hao Q, Dahl HA, Møller RS, Pal DK.

NPJ Genom Med. 2018 May 10;3:13. doi: 10.1038/s41525-018-0052-9. eCollection 2018.


Effect of low energy diet for eight weeks to adults with overweight or obesity on folate, retinol, vitamin B12, D and E status and the degree of inflammation: a post hoc analysis of a randomized intervention trial.

Geiker NRW, Veller M, Kjoelbaek L, Jakobsen J, Ritz C, Raben A, Astrup A, Lorenzen JK, Larsen LH, Bügel S.

Nutr Metab (Lond). 2018 Apr 10;15:24. doi: 10.1186/s12986-018-0263-1. eCollection 2018.


Analysis of circulating angiopoietin-like protein 3 and genetic variants in lipid metabolism and liver health: the DiOGenes study.

Hess AL, Carayol J, Blædel T, Hager J, Di Cara A, Astrup A, Saris WHM, Larsen LH, Valsesia A.

Genes Nutr. 2018 Apr 2;13:7. doi: 10.1186/s12263-018-0597-3. eCollection 2018.


Fish oil as a potential activator of brown and beige fat thermogenesis.

Lund J, Larsen LH, Lauritzen L.

Adipocyte. 2018;7(2):88-95. doi: 10.1080/21623945.2018.1442980. Epub 2018 Mar 9. Review.


Modulation of task-related cortical connectivity in the acute and subacute phase after stroke.

Larsen LH, Zibrandtsen IC, Wienecke T, Kjaer TW, Langberg H, Nielsen JB, Christensen MS.

Eur J Neurosci. 2018 Apr;47(8):1024-1032. doi: 10.1111/ejn.13874. Epub 2018 Mar 9.


Differential Contributions of Specimen Types, Culturing, and 16S rRNA Sequencing in Diagnosis of Prosthetic Joint Infections.

Larsen LH, Khalid V, Xu Y, Thomsen TR, Schønheyder HC; the PRIS Study Group.

J Clin Microbiol. 2018 Apr 25;56(5). pii: e01351-17. doi: 10.1128/JCM.01351-17. Print 2018 May.


Experimental Low Back Pain Decreased Trunk Muscle Activity in Currently Asymptomatic Recurrent Low Back Pain Patients During Step Tasks.

Larsen LH, Hirata RP, Graven-Nielsen T.

J Pain. 2018 May;19(5):542-551. doi: 10.1016/j.jpain.2017.12.263. Epub 2018 Jan 8.


Calcium intake and the associations with faecal fat and energy excretion, and lipid profile in a free-living population.

Kjølbæk L, Lorenzen JK, Larsen LH, Astrup A.

J Nutr Sci. 2017 Sep 19;6:e50. doi: 10.1017/jns.2017.55. eCollection 2017.


Unchanged mitochondrial phenotype, but accumulation of lipids in the myometrium in obese pregnant women.

Gam CMBF, Larsen LH, Mortensen OH, Engelbrechtsen L, Poulsen SS, Qvortrup K, Mathiesen ER, Damm P, Quistorff B.

J Physiol. 2017 Dec 1;595(23):7109-7122. doi: 10.1113/JP274838. Epub 2017 Nov 9.


Corticomuscular coherence in the acute and subacute phase after stroke.

Larsen LH, Zibrandtsen IC, Wienecke T, Kjaer TW, Christensen MS, Nielsen JB, Langberg H.

Clin Neurophysiol. 2017 Nov;128(11):2217-2226. doi: 10.1016/j.clinph.2017.08.033. Epub 2017 Sep 22.


Six-minute walking test and long term prognosis in patients with asymptomatic aortic valve stenosis.

Sigvardsen PE, Larsen LH, Carstensen HG, Kühl JT, Møgelvang R, Hassager C, Køber L, Kofoed KF.

Int J Cardiol. 2017 Dec 15;249:334-339. doi: 10.1016/j.ijcard.2017.09.183. Epub 2017 Sep 27.


Gestational Protein Restriction in Wistar Rats; Effect of Taurine Supplementation on Properties of Newborn Skeletal Muscle.

Larsen LH, Sandø-Pedersen S, Ørstrup LKH, Grunnet N, Quistorff B, Mortensen OH.

Adv Exp Med Biol. 2017;975 Pt 1:413-433. doi: 10.1007/978-94-024-1079-2_34.


High intake of dairy during energy restriction does not affect energy balance or the intestinal microflora compared with low dairy intake in overweight individuals in a randomized controlled trial.

Bendtsen LQ, Blædel T, Holm JB, Lorenzen JK, Mark AB, Kiilerich P, Kristiansen K, Astrup A, Larsen LH.

Appl Physiol Nutr Metab. 2018 Jan;43(1):1-10. doi: 10.1139/apnm-2017-0234. Epub 2017 Aug 22.


Protein supplements after weight loss do not improve weight maintenance compared with recommended dietary protein intake despite beneficial effects on appetite sensation and energy expenditure: a randomized, controlled, double-blinded trial.

Kjølbæk L, Sørensen LB, Søndertoft NB, Rasmussen CK, Lorenzen JK, Serena A, Astrup A, Larsen LH.

Am J Clin Nutr. 2017 Aug;106(2):684-697. doi: 10.3945/ajcn.115.129528. Epub 2017 Jul 5.


A randomised, controlled, crossover study of the effect of diet on angiopoietin-like protein 4 (ANGPTL4) through modification of the gut microbiome.

Blædel T, Holm JB, Sundekilde UK, Schmedes MS, Hess AL, Lorenzen JK, Kristiansen K, Dalsgaard TK, Astrup A, Larsen LH.

J Nutr Sci. 2016 Dec 6;5:e45. doi: 10.1017/jns.2016.38. eCollection 2016.


Microbiological diagnosis of device-related biofilm infections.

Xu Y, Larsen LH, Lorenzen J, Hall-Stoodley L, Kikhney J, Moter A, Thomsen TR.

APMIS. 2017 Apr;125(4):289-303. doi: 10.1111/apm.12676. Review.


Common genetic variants are associated with lower serum 25-hydroxyvitamin D concentrations across the year among children at northern latitudes.

Petersen RA, Larsen LH, Damsgaard CT, Sørensen LB, Hjorth MF, Andersen R, Tetens I, Krarup H, Ritz C, Astrup A, Michaelsen KF, Mølgaard C.

Br J Nutr. 2017 Mar;117(6):829-838. doi: 10.1017/S0007114517000538. Epub 2017 Apr 6.


Prognostic implications of left ventricular asymmetry in patients with asymptomatic aortic valve stenosis.

Sigvardsen PE, Larsen LH, Carstensen HG, Sørgaard M, Hindsø L, Hassager C, Køber L, Møgelvang R, Kofoed KF.

Eur Heart J Cardiovasc Imaging. 2018 Feb 1;19(2):168-175. doi: 10.1093/ehjci/jew339.


Pain-evoked trunk muscle activity changes during fatigue and DOMS.

Larsen LH, Hirata RP, Graven-Nielsen T.

Eur J Pain. 2017 May;21(5):907-917. doi: 10.1002/ejp.993. Epub 2017 Jan 20.


Mutations in GABRB3: From febrile seizures to epileptic encephalopathies.

Møller RS, Wuttke TV, Helbig I, Marini C, Johannesen KM, Brilstra EH, Vaher U, Borggraefe I, Talvik I, Talvik T, Kluger G, Francois LL, Lesca G, de Bellescize J, Blichfeldt S, Chatron N, Holert N, Jacobs J, Swinkels M, Betzler C, Syrbe S, Nikanorova M, Myers CT, Larsen LH, Vejzovic S, Pendziwiat M, von Spiczak S, Hopkins S, Dubbs H, Mang Y, Mukhin K, Holthausen H, van Gassen KL, Dahl HA, Tommerup N, Mefford HC, Rubboli G, Guerrini R, Lemke JR, Lerche H, Muhle H, Maljevic S.

Neurology. 2017 Jan 31;88(5):483-492. doi: 10.1212/WNL.0000000000003565. Epub 2017 Jan 4.


Germline and somatic mutations in the MTOR gene in focal cortical dysplasia and epilepsy.

Møller RS, Weckhuysen S, Chipaux M, Marsan E, Taly V, Bebin EM, Hiatt SM, Prokop JW, Bowling KM, Mei D, Conti V, de la Grange P, Ferrand-Sorbets S, Dorfmüller G, Lambrecq V, Larsen LH, Leguern E, Guerrini R, Rubboli G, Cooper GM, Baulac S.

Neurol Genet. 2016 Oct 31;2(6):e118. eCollection 2016 Dec.


Gene Panel Testing in Epileptic Encephalopathies and Familial Epilepsies.

Møller RS, Larsen LH, Johannesen KM, Talvik I, Talvik T, Vaher U, Miranda MJ, Farooq M, Nielsen JE, Svendsen LL, Kjelgaard DB, Linnet KM, Hao Q, Uldall P, Frangu M, Tommerup N, Baig SM, Abdullah U, Born AP, Gellert P, Nikanorova M, Olofsson K, Jepsen B, Marjanovic D, Al-Zehhawi LI, Peñalva SJ, Krag-Olsen B, Brusgaard K, Hjalgrim H, Rubboli G, Pal DK, Dahl HA.

Mol Syndromol. 2016 Sep;7(4):210-219. Epub 2016 Aug 20.


Phenotypic spectrum of GABRA1: From generalized epilepsies to severe epileptic encephalopathies.

Johannesen K, Marini C, Pfeffer S, Møller RS, Dorn T, Niturad CE, Gardella E, Weber Y, Søndergård M, Hjalgrim H, Nikanorova M, Becker F, Larsen LH, Dahl HA, Maier O, Mei D, Biskup S, Klein KM, Reif PS, Rosenow F, Elias AF, Hudson C, Helbig KL, Schubert-Bast S, Scordo MR, Craiu D, Djémié T, Hoffman-Zacharska D, Caglayan H, Helbig I, Serratosa J, Striano P, De Jonghe P, Weckhuysen S, Suls A, Muru K, Talvik I, Talvik T, Muhle H, Borggraefe I, Rost I, Guerrini R, Lerche H, Lemke JR, Rubboli G, Maljevic S.

Neurology. 2016 Sep 13;87(11):1140-51. doi: 10.1212/WNL.0000000000003087. Epub 2016 Aug 12.


Biological effects of marine diesel oil exposure in red king crab (Paralithodes camtschaticus) assessed through a water and foodborne exposure experiment.

Sagerup K, Nahrgang J, Frantzen M, Larsen LH, Geraudie P.

Mar Environ Res. 2016 Aug;119:126-35. doi: 10.1016/j.marenvres.2016.05.027. Epub 2016 May 30.


In vivo gene expression in a Staphylococcus aureus prosthetic joint infection characterized by RNA sequencing and metabolomics: a pilot study.

Xu Y, Maltesen RG, Larsen LH, Schønheyder HC, Le VQ, Nielsen JL, Nielsen PH, Thomsen TR, Nielsen KL.

BMC Microbiol. 2016 May 5;16:80. doi: 10.1186/s12866-016-0695-6.


Metabolic Effects of a 24-Week Energy-Restricted Intervention Combined with Low or High Dairy Intake in Overweight Women: An NMR-Based Metabolomics Investigation.

Zheng H, Lorenzen JK, Astrup A, Larsen LH, Yde CC, Clausen MR, Bertram HC.

Nutrients. 2016 Feb 23;8(3):108. doi: 10.3390/nu8030108.


Short-term effects of dietary advanced glycation end products in rats.

Poulsen MW, Andersen JM, Hedegaard RV, Madsen AN, Krath BN, Monošík R, Bak MJ, Nielsen J, Holst B, Skibsted LH, Larsen LH, Dragsted LO.

Br J Nutr. 2016 Feb 28;115(4):629-36. doi: 10.1017/S0007114515004833.


Changes in corticospinal drive to spinal motoneurones following tablet-based practice of manual dexterity.

Larsen LH, Jensen T, Christensen MS, Lundbye-Jensen J, Langberg H, Nielsen JB.

Physiol Rep. 2016 Feb;4(2). pii: e12684. doi: 10.14814/phy2.12684.


Can We Prevent Obesity-Related Metabolic Diseases by Dietary Modulation of the Gut Microbiota?

Brahe LK, Astrup A, Larsen LH.

Adv Nutr. 2016 Jan 15;7(1):90-101. doi: 10.3945/an.115.010587. Print 2016 Jan. Review.


Benign infantile seizures and paroxysmal dyskinesia caused by an SCN8A mutation.

Gardella E, Becker F, Møller RS, Schubert J, Lemke JR, Larsen LH, Eiberg H, Nothnagel M, Thiele H, Altmüller J, Syrbe S, Merkenschlager A, Bast T, Steinhoff B, Nürnberg P, Mang Y, Bakke Møller L, Gellert P, Heron SE, Dibbens LM, Weckhuysen S, Dahl HA, Biskup S, Tommerup N, Hjalgrim H, Lerche H, Beniczky S, Weber YG.

Ann Neurol. 2016 Mar;79(3):428-36. doi: 10.1002/ana.24580. Epub 2016 Feb 13.


Aortic root, not valve, calcification correlates with coronary artery calcification in patients with severe aortic stenosis: A two-center study.

Henein M, Hällgren P, Holmgren A, Sörensen K, Ibrahimi P, Kofoed KF, Larsen LH, Hassager C.

Atherosclerosis. 2015 Dec;243(2):631-7. doi: 10.1016/j.atherosclerosis.2015.10.014. Epub 2015 Oct 22.


Reorganized Trunk Muscle Activity During Multidirectional Floor Perturbations After Experimental Low Back Pain: A Comparison of Bilateral Versus Unilateral Pain.

Larsen LH, Hirata RP, Graven-Nielsen T.

J Pain. 2016 Feb;17(2):223-35. doi: 10.1016/j.jpain.2015.10.012. Epub 2015 Nov 5.


Prognostic value of multi-detector computed tomography in asymptomatic aortic valve stenosis.

Larsen LH, Kofoed KF, Carstensen HG, Dalsgaard M, Ersbøll MK, Køber L, Hassager C.

Int J Cardiol. 2016 Jan 15;203:331-7. doi: 10.1016/j.ijcard.2015.10.088. Epub 2015 Oct 22.


Effectiveness and drug adherence of biologic monotherapy in routine care of patients with rheumatoid arthritis: a cohort study of patients registered in the Danish biologics registry.

Jørgensen TS, Kristensen LE, Christensen R, Bliddal H, Lorenzen T, Hansen MS, Østergaard M, Jensen J, Zanjani L, Laursen T, Butt S, Dam MY, Lindegaard HM, Espesen J, Hendricks O, Kumar P, Kincses A, Larsen LH, Andersen M, Næser EK, Jensen DV, Grydehøj J, Unger B, Dufour N, Sørensen V, Vildhøj S, Hansen IM, Raun J, Krogh NS, Hetland ML.

Rheumatology (Oxford). 2015 Dec;54(12):2156-65. doi: 10.1093/rheumatology/kev216. Epub 2015 Jul 13.


Dietary modulation of the gut microbiota--a randomised controlled trial in obese postmenopausal women.

Brahe LK, Le Chatelier E, Prifti E, Pons N, Kennedy S, Blædel T, Håkansson J, Dalsgaard TK, Hansen T, Pedersen O, Astrup A, Ehrlich SD, Larsen LH.

Br J Nutr. 2015 Aug 14;114(3):406-17. doi: 10.1017/S0007114515001786. Epub 2015 Jul 2.


Mutations in KCNT1 cause a spectrum of focal epilepsies.

Møller RS, Heron SE, Larsen LH, Lim CX, Ricos MG, Bayly MA, van Kempen MJ, Klinkenberg S, Andrews I, Kelley K, Ronen GM, Callen D, McMahon JM, Yendle SC, Carvill GL, Mefford HC, Nabbout R, Poduri A, Striano P, Baglietto MG, Zara F, Smith NJ, Pridmore C, Gardella E, Nikanorova M, Dahl HA, Gellert P, Scheffer IE, Gunning B, Kragh-Olsen B, Dibbens LM.

Epilepsia. 2015 Sep;56(9):e114-20. doi: 10.1111/epi.13071. Epub 2015 Jun 30.


Specific gut microbiota features and metabolic markers in postmenopausal women with obesity.

Brahe LK, Le Chatelier E, Prifti E, Pons N, Kennedy S, Hansen T, Pedersen O, Astrup A, Ehrlich SD, Larsen LH.

Nutr Diabetes. 2015 Jun 15;5:e159. doi: 10.1038/nutd.2015.9.


Basal longitudinal strain predicts future aortic valve replacement in asymptomatic patients with aortic stenosis.

Carstensen HG, Larsen LH, Hassager C, Kofoed KF, Jensen JS, Mogelvang R.

Eur Heart J Cardiovasc Imaging. 2016 Mar;17(3):283-92. doi: 10.1093/ehjci/jev143. Epub 2015 Jun 14.


Tissue Velocities and Myocardial Deformation in Asymptomatic and Symptomatic Aortic Stenosis.

Carstensen HG, Larsen LH, Hassager C, Kofoed KF, Dalsgaard M, Kristensen CB, Jensen JS, Mogelvang R.

J Am Soc Echocardiogr. 2015 Aug;28(8):969-80. doi: 10.1016/j.echo.2015.03.013. Epub 2015 May 2.


Clinical Phenotype of De Novo GNAO1 Mutation: Case Report and Review of Literature.

Talvik I, Møller RS, Vaher M, Vaher U, Larsen LH, Dahl HA, Ilves P, Talvik T.

Child Neurol Open. 2015 May 5;2(2):2329048X15583717. doi: 10.1177/2329048X15583717. eCollection 2015 Apr-Jun.

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