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Items: 1 to 50 of 79

1.

Combined use of subclinical hydroxyurea and CHK1 inhibitor effectively controls melanoma and lung cancer progression, with reduced normal tissue toxicity compared to gemcitabine.

Oo ZY, Proctor M, Stevenson AJ, Nazareth D, Fernando M, Daignault SM, Lanagan C, Walpole S, Bonazzi V, Škalamera D, Snell C, Haass NK, Larsen JE, Gabrielli B.

Mol Oncol. 2019 Jul;13(7):1503-1518. doi: 10.1002/1878-0261.12497. Epub 2019 Jun 14.

2.

Assessment of a landfill methane emission screening method using an unmanned aerial vehicle mounted thermal infrared camera - A field study.

Fjelsted L, Christensen AG, Larsen JE, Kjeldsen P, Scheutz C.

Waste Manag. 2019 Mar 15;87:893-904. doi: 10.1016/j.wasman.2018.05.031. Epub 2018 May 28.

PMID:
29853253
3.

Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells.

Walser TC, Jing Z, Tran LM, Lin YQ, Yakobian N, Wang G, Krysan K, Zhu LX, Sharma S, Lee MH, Belperio JA, Ooi AT, Gomperts BN, Shay JW, Larsen JE, Minna JD, Hong LS, Fishbein MC, Dubinett SM.

Cancer Res. 2018 Apr 15;78(8):1986-1999. doi: 10.1158/0008-5472.CAN-17-0315. Epub 2018 Feb 5.

4.

Is negative self-referent bias an endophenotype for depression? An fMRI study of emotional self-referent words in twins at high vs. low risk of depression.

Miskowiak KW, Larsen JE, Harmer CJ, Siebner HR, Kessing LV, Macoveanu J, Vinberg M.

J Affect Disord. 2018 Jan 15;226:267-273. doi: 10.1016/j.jad.2017.10.013. Epub 2017 Oct 3.

PMID:
29020651
5.

Phototrophic microbes form endolithic biofilms in ikaite tufa columns (SW Greenland).

Trampe E, Castenholz RW, Larsen JEN, Kühl M.

Environ Microbiol. 2017 Nov;19(11):4754-4770. doi: 10.1111/1462-2920.13940. Epub 2017 Nov 2.

PMID:
28949068
6.

Identification of a Human Airway Epithelial Cell Subpopulation with Altered Biophysical, Molecular, and Metastatic Properties.

Pagano PC, Tran LM, Bendris N, O'Byrne S, Tse HT, Sharma S, Hoech JW, Park SJ, Liclican EL, Jing Z, Li R, Krysan K, Paul MK, Fontebasso Y, Larsen JE, Hakimi S, Seki A, Fishbein MC, Gimzewski JK, Carlo DD, Minna JD, Walser TC, Dubinett SM.

Cancer Prev Res (Phila). 2017 Sep;10(9):514-524. doi: 10.1158/1940-6207.CAPR-16-0335. Epub 2017 Jul 28.

7.

Exosomes derived from mesenchymal non-small cell lung cancer cells promote chemoresistance.

Lobb RJ, van Amerongen R, Wiegmans A, Ham S, Larsen JE, Möller A.

Int J Cancer. 2017 Aug 1;141(3):614-620. doi: 10.1002/ijc.30752. Epub 2017 May 12.

8.

Combination Therapy Targeting BCL6 and Phospho-STAT3 Defeats Intratumor Heterogeneity in a Subset of Non-Small Cell Lung Cancers.

Deb D, Rajaram S, Larsen JE, Dospoy PD, Marullo R, Li LS, Avila K, Xue F, Cerchietti L, Minna JD, Altschuler SJ, Wu LF.

Cancer Res. 2017 Jun 1;77(11):3070-3081. doi: 10.1158/0008-5472.CAN-15-3052. Epub 2017 Apr 4.

9.

SensibleSleep: A Bayesian Model for Learning Sleep Patterns from Smartphone Events.

Cuttone A, Bækgaard P, Sekara V, Jonsson H, Larsen JE, Lehmann S.

PLoS One. 2017 Jan 11;12(1):e0169901. doi: 10.1371/journal.pone.0169901. eCollection 2017.

10.

The GO-ACTIWE randomized controlled trial - An interdisciplinary study designed to investigate the health effects of active commuting and leisure time physical activity.

Rosenkilde M, Petersen MB, Gram AS, Quist JS, Winther J, Kamronn SD, Milling DH, Larsen JE, Jespersen AP, Stallknecht B.

Contemp Clin Trials. 2017 Feb;53:122-129. doi: 10.1016/j.cct.2016.12.019. Epub 2016 Dec 19.

PMID:
28007633
11.

PROTOCADHERIN 7 Acts through SET and PP2A to Potentiate MAPK Signaling by EGFR and KRAS during Lung Tumorigenesis.

Zhou X, Updegraff BL, Guo Y, Peyton M, Girard L, Larsen JE, Xie XJ, Zhou Y, Hwang TH, Xie Y, Rodriguez-Canales J, Villalobos P, Behrens C, Wistuba II, Minna JD, O'Donnell KA.

Cancer Res. 2017 Jan 1;77(1):187-197. doi: 10.1158/0008-5472.CAN-16-1267-T. Epub 2016 Nov 7.

12.

ZEB1 drives epithelial-to-mesenchymal transition in lung cancer.

Larsen JE, Nathan V, Osborne JK, Farrow RK, Deb D, Sullivan JP, Dospoy PD, Augustyn A, Hight SK, Sato M, Girard L, Behrens C, Wistuba II, Gazdar AF, Hayward NK, Minna JD.

J Clin Invest. 2016 Sep 1;126(9):3219-35. doi: 10.1172/JCI76725. Epub 2016 Aug 8.

13.

In situ Dynamics of O2, pH, Light, and Photosynthesis in Ikaite Tufa Columns (Ikka Fjord, Greenland)-A Unique Microbial Habitat.

Trampe EC, Larsen JE, Glaring MA, Stougaard P, Kühl M.

Front Microbiol. 2016 May 19;7:722. doi: 10.3389/fmicb.2016.00722. eCollection 2016.

14.

Validation of SCT Methylation as a Hallmark Biomarker for Lung Cancers.

Zhang YA, Ma X, Sathe A, Fujimoto J, Wistuba I, Lam S, Yatabe Y, Wang YW, Stastny V, Gao B, Larsen JE, Girard L, Liu X, Song K, Behrens C, Kalhor N, Xie Y, Zhang MQ, Minna JD, Gazdar AF.

J Thorac Oncol. 2016 Mar;11(3):346-360. doi: 10.1016/j.jtho.2015.11.004. Epub 2015 Dec 25.

15.

Cancer-Specific Production of N-Acetylaspartate via NAT8L Overexpression in Non-Small Cell Lung Cancer and Its Potential as a Circulating Biomarker.

Lou TF, Sethuraman D, Dospoy P, Srivastva P, Kim HS, Kim J, Ma X, Chen PH, Huffman KE, Frink RE, Larsen JE, Lewis C, Um SW, Kim DH, Ahn JM, DeBerardinis RJ, White MA, Minna JD, Yoo H.

Cancer Prev Res (Phila). 2016 Jan;9(1):43-52. doi: 10.1158/1940-6207.CAPR-14-0287. Epub 2015 Oct 28.

16.

Nuclear Receptor Expression and Function in Human Lung Cancer Pathogenesis.

Kim J, Sato M, Choi JW, Kim HW, Yeh BI, Larsen JE, Minna JD, Cha JH, Jeong Y.

PLoS One. 2015 Aug 5;10(8):e0134842. doi: 10.1371/journal.pone.0134842. eCollection 2015.

17.

Systematic siRNA Screen Unmasks NSCLC Growth Dependence by Palmitoyltransferase DHHC5.

Tian H, Lu JY, Shao C, Huffman KE, Carstens RM, Larsen JE, Girard L, Liu H, Rodriguez-Canales J, Frenkel EP, Wistuba II, Minna JD, Hofmann SL.

Mol Cancer Res. 2015 Apr;13(4):784-94. doi: 10.1158/1541-7786.MCR-14-0608. Epub 2015 Jan 8.

18.

ASCL1 is a lineage oncogene providing therapeutic targets for high-grade neuroendocrine lung cancers.

Augustyn A, Borromeo M, Wang T, Fujimoto J, Shao C, Dospoy PD, Lee V, Tan C, Sullivan JP, Larsen JE, Girard L, Behrens C, Wistuba II, Xie Y, Cobb MH, Gazdar AF, Johnson JE, Minna JD.

Proc Natl Acad Sci U S A. 2014 Oct 14;111(41):14788-93. doi: 10.1073/pnas.1410419111. Epub 2014 Sep 29.

19.

Genetic transformation of Fusarium avenaceum by Agrobacterium tumefaciens mediated transformation and the development of a USER-Brick vector construction system.

Sørensen LQ, Lysøe E, Larsen JE, Khorsand-Jamal P, Nielsen KF, Frandsen RJ.

BMC Mol Biol. 2014 Jul 22;15:15. doi: 10.1186/1471-2199-15-15.

20.

Loss of miR125a expression in a model of K-ras-dependent pulmonary premalignancy.

Liclican EL, Walser TC, Hazra S, Krysan K, Park SJ, Pagano PC, Gardner BK, Larsen JE, Minna JD, Dubinett SM.

Cancer Prev Res (Phila). 2014 Aug;7(8):845-55. doi: 10.1158/1940-6207.CAPR-14-0063. Epub 2014 Jun 9.

21.

Measuring large-scale social networks with high resolution.

Stopczynski A, Sekara V, Sapiezynski P, Cuttone A, Madsen MM, Larsen JE, Lehmann S.

PLoS One. 2014 Apr 25;9(4):e95978. doi: 10.1371/journal.pone.0095978. eCollection 2014.

22.

The smartphone brain scanner: a portable real-time neuroimaging system.

Stopczynski A, Stahlhut C, Larsen JE, Petersen MK, Hansen LK.

PLoS One. 2014 Feb 5;9(2):e86733. doi: 10.1371/journal.pone.0086733. eCollection 2014. Erratum in: PLoS One. 2014;9(4):e96652.

23.

Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer.

Kim HS, Mendiratta S, Kim J, Pecot CV, Larsen JE, Zubovych I, Seo BY, Kim J, Eskiocak B, Chung H, McMillan E, Wu S, De Brabander J, Komurov K, Toombs JE, Wei S, Peyton M, Williams N, Gazdar AF, Posner BA, Brekken RA, Sood AK, Deberardinis RJ, Roth MG, Minna JD, White MA.

Cell. 2013 Oct 24;155(3):552-66. doi: 10.1016/j.cell.2013.09.041. Epub 2013 Oct 24.

24.

Ras regulates kinesin 13 family members to control cell migration pathways in transformed human bronchial epithelial cells.

Zaganjor E, Osborne JK, Weil LM, Diaz-Martinez LA, Gonzales JX, Singel SM, Larsen JE, Girard L, Minna JD, Cobb MH.

Oncogene. 2014 Nov 20;33(47):5457-66. doi: 10.1038/onc.2013.486. Epub 2013 Nov 18.

25.

Smartphones as pocketable labs: visions for mobile brain imaging and neurofeedback.

Stopczynski A, Stahlhut C, Petersen MK, Larsen JE, Jensen CF, Ivanova MG, Andersen TS, Hansen LK.

Int J Psychophysiol. 2014 Jan;91(1):54-66. doi: 10.1016/j.ijpsycho.2013.08.007. Epub 2013 Aug 29.

PMID:
23994206
26.

NeuroD1 regulation of migration accompanies the differential sensitivity of neuroendocrine carcinomas to TrkB inhibition.

Osborne JK, Larsen JE, Gonzales JX, Shames DS, Sato M, Wistuba II, Girard L, Minna JD, Cobb MH.

Oncogenesis. 2013 Aug 19;2:e63. doi: 10.1038/oncsis.2013.24.

27.

NeuroD1 regulates survival and migration of neuroendocrine lung carcinomas via signaling molecules TrkB and NCAM.

Osborne JK, Larsen JE, Shields MD, Gonzales JX, Shames DS, Sato M, Kulkarni A, Wistuba II, Girard L, Minna JD, Cobb MH.

Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6524-9. doi: 10.1073/pnas.1303932110. Epub 2013 Apr 3.

28.

Human lung epithelial cells progressed to malignancy through specific oncogenic manipulations.

Sato M, Larsen JE, Lee W, Sun H, Shames DS, Dalvi MP, Ramirez RD, Tang H, DiMaio JM, Gao B, Xie Y, Wistuba II, Gazdar AF, Shay JW, Minna JD.

Mol Cancer Res. 2013 Jun;11(6):638-50. doi: 10.1158/1541-7786.MCR-12-0634-T. Epub 2013 Feb 28.

29.

An evaluation of EEG scanner's dependence on the imaging technique, forward model computation method, and array dimensionality.

Stahlhut C, Attias HT, Stopczynski A, Petersen MK, Larsen JE, Hansen LK.

Conf Proc IEEE Eng Med Biol Soc. 2012;2012:1538-41. doi: 10.1109/EMBC.2012.6346235.

PMID:
23366196
30.

Epithelial-mesenchymal transition increases tumor sensitivity to COX-2 inhibition by apricoxib.

Kirane A, Toombs JE, Larsen JE, Ostapoff KT, Meshaw KR, Zaknoen S, Brekken RA, Burrows FJ.

Carcinogenesis. 2012 Sep;33(9):1639-46. doi: 10.1093/carcin/bgs195. Epub 2012 Jun 7.

31.

Array-comparative genomic hybridization reveals loss of SOCS6 is associated with poor prognosis in primary lung squamous cell carcinoma.

Sriram KB, Larsen JE, Savarimuthu Francis SM, Wright CM, Clarke BE, Duhig EE, Brown KM, Hayward NK, Yang IA, Bowman RV, Fong KM.

PLoS One. 2012;7(2):e30398. doi: 10.1371/journal.pone.0030398. Epub 2012 Feb 17.

32.

Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome.

Ihle NT, Byers LA, Kim ES, Saintigny P, Lee JJ, Blumenschein GR, Tsao A, Liu S, Larsen JE, Wang J, Diao L, Coombes KR, Chen L, Zhang S, Abdelmelek MF, Tang X, Papadimitrakopoulou V, Minna JD, Lippman SM, Hong WK, Herbst RS, Wistuba II, Heymach JV, Powis G.

J Natl Cancer Inst. 2012 Feb 8;104(3):228-39. doi: 10.1093/jnci/djr523. Epub 2012 Jan 13.

33.

Targeted therapies for lung cancer: clinical experience and novel agents.

Larsen JE, Cascone T, Gerber DE, Heymach JV, Minna JD.

Cancer J. 2011 Nov-Dec;17(6):512-27. doi: 10.1097/PPO.0b013e31823e701a. Review.

34.

Prediction of drug efficacy for cancer treatment based on comparative analysis of chemosensitivity and gene expression data.

Wan P, Li Q, Larsen JE, Eklund AC, Parlesak A, Rigina O, Nielsen SJ, Björkling F, Jónsdóttir SÓ.

Bioorg Med Chem. 2012 Jan 1;20(1):167-76. doi: 10.1016/j.bmc.2011.11.019. Epub 2011 Nov 22.

PMID:
22154557
35.

Molecular biology of lung cancer: clinical implications.

Larsen JE, Minna JD.

Clin Chest Med. 2011 Dec;32(4):703-40. doi: 10.1016/j.ccm.2011.08.003. Epub 2011 Oct 7. Review.

36.

SMAC mimetic (JP1201) sensitizes non-small cell lung cancers to multiple chemotherapy agents in an IAP-dependent but TNF-α-independent manner.

Greer RM, Peyton M, Larsen JE, Girard L, Xie Y, Gazdar AF, Harran P, Wang L, Brekken RA, Wang X, Minna JD.

Cancer Res. 2011 Dec 15;71(24):7640-8. doi: 10.1158/0008-5472.CAN-10-3947. Epub 2011 Nov 2.

37.

Genes and gene ontologies common to airflow obstruction and emphysema in the lungs of patients with COPD.

Savarimuthu Francis SM, Larsen JE, Pavey SJ, Duhig EE, Clarke BE, Bowman RV, Hayward NK, Fong KM, Yang IA.

PLoS One. 2011 Mar 15;6(3):e17442. doi: 10.1371/journal.pone.0017442.

38.

Knockdown of oncogenic KRAS in non-small cell lung cancers suppresses tumor growth and sensitizes tumor cells to targeted therapy.

Sunaga N, Shames DS, Girard L, Peyton M, Larsen JE, Imai H, Soh J, Sato M, Yanagitani N, Kaira K, Xie Y, Gazdar AF, Mori M, Minna JD.

Mol Cancer Ther. 2011 Feb;10(2):336-46. doi: 10.1158/1535-7163.MCT-10-0750.

39.

Aldehyde dehydrogenase activity selects for lung adenocarcinoma stem cells dependent on notch signaling.

Sullivan JP, Spinola M, Dodge M, Raso MG, Behrens C, Gao B, Schuster K, Shao C, Larsen JE, Sullivan LA, Honorio S, Xie Y, Scaglioni PP, DiMaio JM, Gazdar AF, Shay JW, Wistuba II, Minna JD.

Cancer Res. 2010 Dec 1;70(23):9937-48. doi: 10.1158/0008-5472.CAN-10-0881. Epub 2010 Nov 30.

40.

Genomic medicine in non-small cell lung cancer: paving the path to personalized care.

Sriram KB, Larsen JE, Yang IA, Bowman RV, Fong KM.

Respirology. 2011 Feb;16(2):257-63. doi: 10.1111/j.1440-1843.2010.01892.x. Review.

PMID:
21044232
41.

MicroRNA-218 is deleted and downregulated in lung squamous cell carcinoma.

Davidson MR, Larsen JE, Yang IA, Hayward NK, Clarke BE, Duhig EE, Passmore LH, Bowman RV, Fong KM.

PLoS One. 2010 Sep 3;5(9):e12560. doi: 10.1371/journal.pone.0012560.

42.

ADAM28: a potential oncogene involved in asbestos-related lung adenocarcinomas.

Wright CM, Larsen JE, Hayward NK, Martins MU, Tan ME, Davidson MR, Savarimuthu SM, McLachlan RE, Passmore LH, Windsor MN, Clarke BE, Duhig EE, Yang IA, Bowman RV, Fong KM.

Genes Chromosomes Cancer. 2010 Aug;49(8):688-98. doi: 10.1002/gcc.20779.

PMID:
20544843
43.

BAMLET activates a lysosomal cell death program in cancer cells.

Rammer P, Groth-Pedersen L, Kirkegaard T, Daugaard M, Rytter A, Szyniarowski P, Høyer-Hansen M, Povlsen LK, Nylandsted J, Larsen JE, Jäättelä M.

Mol Cancer Ther. 2010 Jan;9(1):24-32. doi: 10.1158/1535-7163.MCT-09-0559. Epub 2010 Jan 6.

44.

Expression profiling identifies genes involved in emphysema severity.

Francis SM, Larsen JE, Pavey SJ, Bowman RV, Hayward NK, Fong KM, Yang IA.

Respir Res. 2009 Sep 2;10:81. doi: 10.1186/1465-9921-10-81.

45.

Genetic association study of CYP1A1 polymorphisms identifies risk haplotypes in nonsmall cell lung cancer.

Wright CM, Larsen JE, Colosimo ML, Barr JJ, Chen L, McLachlan RE, Yang IA, Bowman RV, Fong KM.

Eur Respir J. 2010 Jan;35(1):152-9. doi: 10.1183/09031936.00120808. Epub 2009 Jul 16.

46.

Meta- and pooled analysis of GSTP1 polymorphism and lung cancer: a HuGE-GSEC review.

Cote ML, Chen W, Smith DW, Benhamou S, Bouchardy C, Butkiewicz D, Fong KM, Gené M, Hirvonen A, Kiyohara C, Larsen JE, Lin P, Raaschou-Nielsen O, Povey AC, Reszka E, Risch A, Schneider J, Schwartz AG, Sorensen M, To-Figueras J, Tokudome S, Pu Y, Yang P, Wenzlaff AS, Wikman H, Taioli E.

Am J Epidemiol. 2009 Apr 1;169(7):802-14. doi: 10.1093/aje/kwn417. Epub 2009 Feb 24.

47.

Region and Field Level Distributions of Aster Yellows Phytoplasma in Small Grain Crops.

Hollingsworth CR, Atkinson LM, Samac DA, Larsen JE, Motteberg CD, Abrahamson MD, Glogoza P, MacRae IV.

Plant Dis. 2008 Apr;92(4):623-630. doi: 10.1094/PDIS-92-4-0623.

PMID:
30769643
48.

Gene expression of lung squamous cell carcinoma reflects mode of lymph node involvement.

Larsen JE, Pavey SJ, Bowman R, Yang IA, Clarke BE, Colosimo ML, Hayward NK, Fong KM.

Eur Respir J. 2007 Jul;30(1):21-5.

49.

Gene expression signature predicts recurrence in lung adenocarcinoma.

Larsen JE, Pavey SJ, Passmore LH, Bowman RV, Hayward NK, Fong KM.

Clin Cancer Res. 2007 May 15;13(10):2946-54.

50.

Distribution of Phoma sclerotioides on Alfalfa and Winter Wheat Crops in the North Central United States.

Larsen JE, Hollingsworth CR, Flor J, Dornbusch MR, Simpson NL, Samac DA.

Plant Dis. 2007 May;91(5):551-558. doi: 10.1094/PDIS-91-5-0551.

PMID:
30780700

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