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Items: 1 to 50 of 210

1.

Epigenetic Age Reversal by Cell-Extrinsic and Cell-Intrinsic Means.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2019 Oct;22(5):439-446. doi: 10.1089/rej.2019.2271.

PMID:
31578938
2.

Roads to the Fountain of Youth? Rejuvenating Intestinal Stem Cells.

Larrick JW, Mendelsohn AR.

Rejuvenation Res. 2019 Aug;22(4):342-347. doi: 10.1089/rej.2019.2251.

PMID:
31364468
3.

Interacting NAD+ and Cell Senescence Pathways Complicate Antiaging Therapies.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2019 Jun;22(3):261-266. doi: 10.1089/rej.2019.2218.

PMID:
31140365
4.

Regulation of S-Nitrosylation in Aging and Senescence.

Larrick JW, Mendelsohn AR.

Rejuvenation Res. 2019 Apr;22(2):171-174. doi: 10.1089/rej.2019.2194.

PMID:
30943847
5.

Cellular Senescence as the Key Intermediate in Tau-Mediated Neurodegeneration.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2018 Dec;21(6):572-579. doi: 10.1089/rej.2018.2155.

PMID:
30489222
6.

Prevention of Senescence in Vasculature Through Quiescence.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2018 Oct;21(5):477-481. doi: 10.1089/rej.2018.2138.

PMID:
30259779
7.

Mitochondrial-Derived Peptides Exacerbate Senescence.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2018 Aug;21(4):369-373. doi: 10.1089/rej.2018.2114. Review.

PMID:
30058454
8.

Finally, a Regimen to Extend Human Life Expectancy.

Larrick JW, Mendelsohn AR.

Rejuvenation Res. 2018 Jun;21(3):278-282. doi: 10.1089/rej.2018.2088.

PMID:
29781380
9.

Telomerase May Paradoxically Accelerate Aging of the DNA Methylome.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2018 Apr;21(2):168-172. doi: 10.1089/rej.2018.2073. Review.

PMID:
29667924
10.

Anti-angiogenic effect of a humanized antibody blocking the Wnt/β-catenin signaling pathway.

Qiu F, Shin Y, Chen D, Cheng R, Chen Q, Zhou K, Larrick JW, Mendelson AR, Ma JX.

Microvasc Res. 2018 Sep;119:29-37. doi: 10.1016/j.mvr.2018.03.011. Epub 2018 Apr 7.

11.

Na+, K+-ATPase Activating Antibody Displays in vitro and in vivo Beneficial Effects in the Pilocarpine Model of Epilepsy.

Freitas ML, Oliveira CV, Mello FK, Funck VR, Fighera MR, Royes LFF, Furian AF, Larrick JW, Oliveira MS.

Neuroscience. 2018 May 1;377:98-104. doi: 10.1016/j.neuroscience.2018.02.044. Epub 2018 Mar 6.

PMID:
29522855
12.

Serlopitant for the treatment of chronic pruritus: Results of a randomized, multicenter, placebo-controlled phase 2 clinical trial.

Yosipovitch G, Ständer S, Kerby MB, Larrick JW, Perlman AJ, Schnipper EF, Zhang X, Tang JY, Luger T, Steinhoff M.

J Am Acad Dermatol. 2018 May;78(5):882-891.e10. doi: 10.1016/j.jaad.2018.02.030. Epub 2018 Feb 17.

13.

ATP Synthase, a Target for Dementia and Aging?

Larrick JW, Larrick JW, Mendelsohn AR.

Rejuvenation Res. 2018 Feb;21(1):61-66. doi: 10.1089/rej.2018.2056.

PMID:
29461942
14.

Mesenchymal Stem Cells for Frailty?

Larrick JW, Mendelsohn AR.

Rejuvenation Res. 2017 Dec;20(6):525-529. doi: 10.1089/rej.2017.2042.

PMID:
29179649
15.

Epigenetic Drift Is a Determinant of Mammalian Lifespan.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2017 Oct;20(5):430-436. doi: 10.1089/rej.2017.2024.

PMID:
28942711
16.

Inflammation, Stem Cells, and the Aging Hypothalamus.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2017 Aug;20(4):346-349. doi: 10.1089/rej.2017.2002. Review.

PMID:
28756738
17.

The NAD+/PARP1/SIRT1 Axis in Aging.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2017 Jun;20(3):244-247. doi: 10.1089/rej.2017.1980.

PMID:
28537485
18.

Interleukin-7 and Immunosenescence.

Nguyen V, Mendelsohn A, Larrick JW.

J Immunol Res. 2017;2017:4807853. doi: 10.1155/2017/4807853. Epub 2017 Apr 6. Review.

19.

Simultaneous exposure to FcγR and FcαR on monocytes and macrophages enhances antitumor activity in vivo.

Li B, Xu L, Tao F, Xie K, Wu Z, Li Y, Li J, Chen K, Pi C, Mendelsohn A, Larrick JW, Gu H, Fang J.

Oncotarget. 2017 Jun 13;8(24):39356-39366. doi: 10.18632/oncotarget.17000.

20.

Rejuvenation by Partial Reprogramming of the Epigenome.

Mendelsohn AR, Larrick JW, Lei JL.

Rejuvenation Res. 2017 Apr;20(2):146-150. doi: 10.1089/rej.2017.1958. Review.

PMID:
28314379
21.

Pharmaceutical Rejuvenation of Age-Associated Decline in Spatial Memory.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2016 Dec;19(6):521-524.

PMID:
27881050
22.

Antibody Engineering & Therapeutics 2016: The Antibody Society's annual meeting, December 11-15, 2016, San Diego, CA.

Larrick JW, Alfenito MR, Scott JK, Parren PW, Burton DR, Bradbury AR, Lemere CA, Messer A, Huston JS, Carter PJ, Veldman T, Chester KA, Schuurman J, Adams GP, Reichert JM.

MAbs. 2016 Nov/Dec;8(8):1425-1434. Epub 2016 Aug 24.

23.

Reversal of Aged Muscle Stem Cell Dysfunction.

Larrick JW, Larrick JW, Mendelsohn AR.

Rejuvenation Res. 2016 Oct;19(5):423-429. Epub 2016 Oct 11.

PMID:
27612523
24.

Uncoupling Mitochondrial Respiration for Diabesity.

Larrick JW, Larrick JW, Mendelsohn AR.

Rejuvenation Res. 2016 Aug;19(4):337-40. doi: 10.1089/rej.2016.1859.

PMID:
27378359
25.

Preclinical Reversal of Atherosclerosis by FDA-Approved Compound that Transforms Cholesterol into an Anti-Inflammatory "Prodrug".

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2016 Jun;19(3):252-5. doi: 10.1089/rej.2016.1849.

PMID:
27241174
26.

Rejuvenating Muscle Stem Cell Function: Restoring Quiescence and Overcoming Senescence.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2016 Apr;19(2):182-6. doi: 10.1089/rej.2016.1829. Review.

PMID:
27000748
27.

Corrigendum: Pharmacologically targeted NMDA receptor antagonism by NitroMemantine for cerebrovascular disease.

Takahashi H, Xia P, Cui J, Talantova M, Bodhinathan K, Li W, Saleem S, Holland EA, Tong G, Piña-Crespo J, Zhang D, Nakanishi N, Larrick JW, McKercher SR, Nakamura T, Wang Y, Lipton SA.

Sci Rep. 2016 Feb 12;6:20750. doi: 10.1038/srep20750. No abstract available.

28.

Thymus Maintenance and Regeneration by Specific Molecular Factors.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2016 Feb;19(1):90-3. doi: 10.1089/rej.2016.1812. Erratum in: Rejuvenation Res. 2016 Jun;19(3):270.

PMID:
26837468
29.

Aging Stem Cells Lose the Capability to Distribute Damaged Proteins Asymmetrically.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2015 Dec;18(6):581-4. doi: 10.1089/rej.2015.1800. Review.

PMID:
26650679
30.

Pharmacologically targeted NMDA receptor antagonism by NitroMemantine for cerebrovascular disease.

Takahashi H, Xia P, Cui J, Talantova M, Bodhinathan K, Li W, Saleem S, Holland EA, Tong G, Piña-Crespo J, Zhang D, Nakanishi N, Larrick JW, McKercher SR, Nakamura T, Wang Y, Lipton SA.

Sci Rep. 2015 Oct 19;5:14781. doi: 10.1038/srep14781. Erratum in: Sci Rep. 2016;6:20750. Saleem, Sofiyan [added].

31.

Antibody Engineering & Therapeutics 2015: The Antibody Society's annual meeting December 7-10, 2015, San Diego, CA.

Parren PW, Burton DR, Bradbury A, Huston JS, Carter PJ, Veldman T, Chester KA, Larrick JW, Alfenito MR, Scott JK, Weiner LM, Adams GP, Reichert JM.

MAbs. 2015;7(6):981-8. doi: 10.1080/19420862.2015.1089707. Epub 2015 Sep 30.

33.

Stem Cell Depletion by Global Disorganization of the H3K9me3 Epigenetic Marker in Aging.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2015 Aug;18(4):371-5. doi: 10.1089/rej.2015.1742. Review.

PMID:
26160351
34.

Contrasting effects of Na+, K+-ATPase activation on seizure activity in acute versus chronic models.

Funck VR, Ribeiro LR, Pereira LM, de Oliveira CV, Grigoletto J, Della-Pace ID, Fighera MR, Royes LF, Furian AF, Larrick JW, Oliveira MS.

Neuroscience. 2015 Jul 9;298:171-9. doi: 10.1016/j.neuroscience.2015.04.031. Epub 2015 Apr 20.

PMID:
25907445
35.

Telomerase redux: ready for prime time?

Larrick JW, Mendelsohn AR.

Rejuvenation Res. 2015 Apr;18(2):185-7. doi: 10.1089/rej.2015.1695.

PMID:
25790341
36.

Antibody engineering and therapeutics conference. The annual meeting of the antibody society, Huntington Beach, CA, December 7-11, 2014.

Larrick JW, Parren P, Huston JS, Plückthun A, Bradbury A, Tomlinson IM, Chester KA, Burton DR, Adams GP, Weiner LM, Scott JK, Alfenito MR, Veldman T, Reichert JM.

MAbs. 2014;6(5):1115-23. doi: 10.4161/19420862.2014.971627.

37.

Systemic factors mediate reversible age-associated brain dysfunction.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2014 Dec;17(6):525-8. doi: 10.1089/rej.2014.1643.

PMID:
25400086
38.

Antibody-membrane switch (AMS) technology for facile cell line development.

Yu B, Wages JM, Larrick JW.

Protein Eng Des Sel. 2014 Oct;27(10):309-15. doi: 10.1093/protein/gzu039. Epub 2014 Sep 14.

PMID:
25225415
39.

Prolonged fasting/refeeding promotes hematopoietic stem cell regeneration and rejuvenation.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2014 Aug;17(4):385-9. doi: 10.1089/rej.2014.1595.

PMID:
25072352
40.

Paradoxical effects of antioxidants on cancer.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2014 Jun;17(3):306-11. doi: 10.1089/rej.2014.1577.

PMID:
24828241
41.

Partial reversal of skeletal muscle aging by restoration of normal NAD⁺ levels.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2014 Feb;17(1):62-9. doi: 10.1089/rej.2014.1546. Review.

PMID:
24410488
42.

Sleep facilitates clearance of metabolites from the brain: glymphatic function in aging and neurodegenerative diseases.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2013 Dec;16(6):518-23. doi: 10.1089/rej.2013.1530. Review.

PMID:
24199995
43.

Trade-offs between anti-aging dietary supplementation and exercise.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2013 Oct;16(5):419-26. doi: 10.1089/rej.2013.1484.

PMID:
23998660
44.

Rejuvenation of aging hearts.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2013 Aug;16(4):330-2. doi: 10.1089/rej.2013.1462. Review.

PMID:
23829663
45.

Affinity maturation and fine functional mapping of an antibody fragment against a novel neutralizing epitope on human vascular endothelial growth factor.

Lamdan H, Gavilondo JV, Muñoz Y, Pupo A, Huerta V, Musacchio A, Pérez L, Ayala M, Rojas G, Balint RF, Larrick JW.

Mol Biosyst. 2013 Aug;9(8):2097-106. doi: 10.1039/c3mb70136k. Epub 2013 May 24.

PMID:
23702826
46.

Dietary modification of the microbiome affects risk for cardiovascular disease.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2013 Jun;16(3):241-4. doi: 10.1089/rej.2013.1447.

PMID:
23656565
47.

Rejuvenation of adult stem cells: is age-associated dysfunction epigenetic?

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2013 Apr;16(2):152-7. doi: 10.1089/rej.2013.1424.

PMID:
23488583
48.

The DNA methylome as a biomarker for epigenetic instability and human aging.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2013 Feb;16(1):74-7. doi: 10.1089/rej.2013.1414.

PMID:
23339475
49.

Fibroblast growth factor-21 is a promising dietary restriction mimetic.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2012 Dec;15(6):624-8. doi: 10.1089/rej.2012.1392. Review.

PMID:
23173578
50.

Dietary restriction: critical co-factors to separate health span from life span benefits.

Mendelsohn AR, Larrick JW.

Rejuvenation Res. 2012 Oct;15(5):523-9. doi: 10.1089/rej.2012.1371.

PMID:
22963324

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