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Items: 1 to 50 of 78

1.

Harnessing adipogenesis to prevent obesity.

Haider N, Larose L.

Adipocyte. 2019 Dec;8(1):98-104. doi: 10.1080/21623945.2019.1583037. Epub 2019 Mar 8.

2.

Nck1 Deficiency Impairs Adipogenesis by Activation of PDGFRα in Preadipocytes.

Haider N, Dusseault J, Larose L.

iScience. 2018 Aug 31;6:22-37. doi: 10.1016/j.isci.2018.07.010. Epub 2018 Jul 19.

3.

Peptide-based sequestration of the adaptor protein Nck1 in pancreatic β cells enhances insulin biogenesis and protects against diabetogenic stresses.

Kefalas G, Jouvet N, Baldwin C, Estall JL, Larose L.

J Biol Chem. 2018 Aug 10;293(32):12516-12524. doi: 10.1074/jbc.RA118.002728. Epub 2018 Jun 25.

4.

PERK leads a hub dictating pancreatic β cell homoeostasis.

Kefalas G, Larose L.

Biol Cell. 2018 Feb;110(2):27-32. doi: 10.1111/boc.201700059. Epub 2017 Dec 15. Review.

PMID:
29168198
5.

IRE1α links Nck1 deficiency to attenuated PTP1B expression in HepG2 cells.

Li H, Li B, Larose L.

Cell Signal. 2017 Aug;36:79-90. doi: 10.1016/j.cellsig.2017.04.017. Epub 2017 Apr 25.

PMID:
28455143
6.

Deletion of inositol-requiring enzyme-1α in podocytes disrupts glomerular capillary integrity and autophagy.

Kaufman DR, Papillon J, Larose L, Iwawaki T, Cybulsky AV.

Mol Biol Cell. 2017 Jun 15;28(12):1636-1651. doi: 10.1091/mbc.E16-12-0828. Epub 2017 Apr 20.

7.

Nck2, an unexpected regulator of adipogenesis.

Haider N, Dusseault J, Rudich A, Larose L.

Adipocyte. 2017 Apr 3;6(2):154-160. doi: 10.1080/21623945.2017.1291102. Epub 2017 Feb 6.

8.

Dissecting the molecular mechanisms that impair stress granule formation in aging cells.

Moujaber O, Mahboubi H, Kodiha M, Bouttier M, Bednarz K, Bakshi R, White J, Larose L, Colmegna I, Stochaj U.

Biochim Biophys Acta Mol Cell Res. 2017 Mar;1864(3):475-486. doi: 10.1016/j.bbamcr.2016.12.008. Epub 2016 Dec 10.

9.

Nck2 Deficiency in Mice Results in Increased Adiposity Associated With Adipocyte Hypertrophy and Enhanced Adipogenesis.

Dusseault J, Li B, Haider N, Goyette MA, Côté JF, Larose L.

Diabetes. 2016 Sep;65(9):2652-66. doi: 10.2337/db15-1559. Epub 2016 Jun 20.

10.

[No available].

Larose L.

Perspect Infirm. 2016 Mar-Apr;13(2):61. French. No abstract available.

PMID:
27156291
11.

mTORC1 and CK2 coordinate ternary and eIF4F complex assembly.

Gandin V, Masvidal L, Cargnello M, Gyenis L, McLaughlan S, Cai Y, Tenkerian C, Morita M, Balanathan P, Jean-Jean O, Stambolic V, Trost M, Furic L, Larose L, Koromilas AE, Asano K, Litchfield D, Larsson O, Topisirovic I.

Nat Commun. 2016 Apr 4;7:11127. doi: 10.1038/ncomms11127.

12.

Nck1 deficiency improves pancreatic β cell survival to diabetes-relevant stresses by modulating PERK activation and signaling.

Yamani L, Li B, Larose L.

Cell Signal. 2015 Dec;27(12):2555-67. doi: 10.1016/j.cellsig.2015.09.016. Epub 2015 Oct 3.

PMID:
26434994
13.

USP19 deubiquitinating enzyme inhibits muscle cell differentiation by suppressing unfolded-protein response signaling.

Wiles B, Miao M, Coyne E, Larose L, Cybulsky AV, Wing SS.

Mol Biol Cell. 2015 Mar 1;26(5):913-23. doi: 10.1091/mbc.E14-06-1129. Epub 2015 Jan 7.

14.

Nck1 depletion induces activation of the PI3K/Akt pathway by attenuating PTP1B protein expression.

Li H, Dusseault J, Larose L.

Cell Commun Signal. 2014 Nov 14;12:71. doi: 10.1186/s12964-014-0071-9.

15.

Interaction of Nck1 and PERK phosphorylated at Y⁵⁶¹ negatively modulates PERK activity and PERK regulation of pancreatic β-cell proinsulin content.

Yamani L, Latreille M, Larose L.

Mol Biol Cell. 2014 Mar;25(5):702-11. doi: 10.1091/mbc.E13-09-0511. Epub 2013 Dec 26.

16.

Casein kinase iγ2 impairs fibroblasts actin stress fibers formation and delays cell cycle progression in g1.

Latreille M, Abu-Thuraia A, Oliva R, Zuo D, Larose L.

Int J Cell Biol. 2012;2012:684684. doi: 10.1155/2012/684684. Epub 2012 Mar 7.

17.

Nck2 promotes human melanoma cell proliferation, migration and invasion in vitro and primary melanoma-derived tumor growth in vivo.

Labelle-Côté M, Dusseault J, Ismaïl S, Picard-Cloutier A, Siegel PM, Larose L.

BMC Cancer. 2011 Oct 12;11:443. doi: 10.1186/1471-2407-11-443.

18.

[A uNick protein].

Labelle-Côté M, Larose L.

Med Sci (Paris). 2011 Aug-Sep;27(8-9):746-52. doi: 10.1051/medsci/2011278017. Epub 2011 Aug 31. Review. French.

19.

Deletion of Nck1 attenuates hepatic ER stress signaling and improves glucose tolerance and insulin signaling in liver of obese mice.

Latreille M, Laberge MK, Bourret G, Yamani L, Larose L.

Am J Physiol Endocrinol Metab. 2011 Mar;300(3):E423-34. doi: 10.1152/ajpendo.00088.2010. Epub 2010 Jun 29.

20.

The Gab1 scaffold regulates RTK-dependent dorsal ruffle formation through the adaptor Nck.

Abella JV, Vaillancourt R, Frigault MM, Ponzo MG, Zuo D, Sangwan V, Larose L, Park M.

J Cell Sci. 2010 Apr 15;123(Pt 8):1306-19. doi: 10.1242/jcs.062570. Epub 2010 Mar 23.

21.

Regulation of process retraction and cell migration by EphA3 is mediated by the adaptor protein Nck1.

Hu T, Shi G, Larose L, Rivera GM, Mayer BJ, Zhou R.

Biochemistry. 2009 Jul 14;48(27):6369-78. doi: 10.1021/bi900831k.

22.

Critical and multiple roles for the CD3epsilon intracytoplasmic tail in double negative to double positive thymocyte differentiation.

Brodeur JF, Li S, da Silva Martins M, Larose L, Dave VP.

J Immunol. 2009 Apr 15;182(8):4844-53. doi: 10.4049/jimmunol.0803679.

23.

Nck-1 interacts with PKR and modulates its activation by dsRNA.

Cardin E, Larose L.

Biochem Biophys Res Commun. 2008 Dec 5;377(1):231-5. doi: 10.1016/j.bbrc.2008.09.112. Epub 2008 Oct 1.

PMID:
18835251
24.

Nck-1 selectively modulates eIF2alphaSer51 phosphorylation by a subset of eIF2alpha-kinases.

Cardin E, Latreille M, Khoury C, Greenwood MT, Larose L.

FEBS J. 2007 Nov;274(22):5865-75. Epub 2007 Oct 18.

25.

Rat nephrin modulates cell morphology via the adaptor protein Nck.

Li H, Zhu J, Aoudjit L, Latreille M, Kawachi H, Larose L, Takano T.

Biochem Biophys Res Commun. 2006 Oct 13;349(1):310-6. Epub 2006 Aug 17.

PMID:
16934223
27.

The adaptor protein Nck interacts with Fas ligand: Guiding the death factor to the cytotoxic immunological synapse.

Lettau M, Qian J, Linkermann A, Latreille M, Larose L, Kabelitz D, Janssen O.

Proc Natl Acad Sci U S A. 2006 Apr 11;103(15):5911-6. Epub 2006 Apr 4.

28.

Nck adaptor proteins link nephrin to the actin cytoskeleton of kidney podocytes.

Jones N, Blasutig IM, Eremina V, Ruston JM, Bladt F, Li H, Huang H, Larose L, Li SS, Takano T, Quaggin SE, Pawson T.

Nature. 2006 Apr 6;440(7085):818-23. Epub 2006 Mar 8.

PMID:
16525419
29.

Nck-dependent activation of extracellular signal-regulated kinase-1 and regulation of cell survival during endoplasmic reticulum stress.

Nguyên DT, Kebache S, Fazel A, Wong HN, Jenna S, Emadali A, Lee EH, Bergeron JJ, Kaufman RJ, Larose L, Chevet E.

Mol Biol Cell. 2004 Sep;15(9):4248-60. Epub 2004 Jun 16.

30.

Metastatic tumor antigen 1 short form (MTA1s) associates with casein kinase I-gamma2, an estrogen-responsive kinase.

Mishra SK, Yang Z, Mazumdar A, Talukder AH, Larose L, Kumar R.

Oncogene. 2004 May 27;23(25):4422-9.

PMID:
15077195
31.

Nck-1 antagonizes the endoplasmic reticulum stress-induced inhibition of translation.

Kebache S, Cardin E, Nguyên DT, Chevet E, Larose L.

J Biol Chem. 2004 Mar 5;279(10):9662-71. Epub 2003 Dec 15.

32.

Block of Na+,K+-ATPase and induction of hybrid death by 4-aminopyridine in cultured cortical neurons.

Wang XQ, Xiao AY, Yang A, LaRose L, Wei L, Yu SP.

J Pharmacol Exp Ther. 2003 May;305(2):502-6. Epub 2003 Jan 21.

PMID:
12606650
33.

The adaptor protein Nck-1 couples the netrin-1 receptor DCC (deleted in colorectal cancer) to the activation of the small GTPase Rac1 through an atypical mechanism.

Li X, Meriane M, Triki I, Shekarabi M, Kennedy TE, Larose L, Lamarche-Vane N.

J Biol Chem. 2002 Oct 4;277(40):37788-97. Epub 2002 Jul 30.

34.

Modulation of protein translation by Nck-1.

Kebache S, Zuo D, Chevet E, Larose L.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5406-11.

35.
36.

Casein kinase I associates with members of the centaurin-alpha family of phosphatidylinositol 3,4,5-trisphosphate-binding proteins.

Dubois T, Kerai P, Zemlickova E, Howell S, Jackson TR, Venkateswarlu K, Cullen PJ, Theibert AB, Larose L, Roach PJ, Aitken A.

J Biol Chem. 2001 Jun 1;276(22):18757-64. Epub 2001 Mar 2.

37.

Functional Rac-1 and Nck signaling networks are required for FGF-2-induced DNA synthesis in MCF-7 cells.

Liu JF, Chevet E, Kebache S, Lemaitre G, Barritault D, Larose L, Crépin M.

Oncogene. 1999 Nov 11;18(47):6425-33.

40.

SHP-1 binds and negatively modulates the c-Kit receptor by interaction with tyrosine 569 in the c-Kit juxtamembrane domain.

Kozlowski M, Larose L, Lee F, Le DM, Rottapel R, Siminovitch KA.

Mol Cell Biol. 1998 Apr;18(4):2089-99.

41.

A casein kinase I activity is constitutively associated with Nck.

Lussier G, Larose L.

J Biol Chem. 1997 Jan 31;272(5):2688-94.

42.

Construction of an SH2 domain-binding site with mixed specificity.

Larose L, Gish G, Pawson T.

J Biol Chem. 1995 Feb 24;270(8):3858-62.

43.

Biochemical analysis of SH2 domain-mediated protein interactions.

Gish G, Larose L, Shen R, Pawson T.

Methods Enzymol. 1995;254:503-23. No abstract available.

PMID:
8531711
44.
45.

Distribution and regulation of natriuretic factor-R1C receptor subtypes in mammalian cell lines.

Féthière J, Graihle R, Larose L, Babinski K, Ong H, De Léan A.

Mol Cell Biochem. 1993 Jul 7;124(1):11-6.

PMID:
8232274
46.

Dietary myo-inositol supplementation does not prevent retinal and glomerular vascular structural changes in chronically diabetic rats.

Tilton RG, Faller AM, LaRose LS, Burgan J, Williamson JR.

J Diabetes Complications. 1993 Jul-Sep;7(3):188-98.

PMID:
8343613
47.

Phosphorylation of atrial natriuretic factor R1 receptor by serine/threonine protein kinases: evidences for receptor regulation.

Larose L, Rondeau JJ, Ong H, De Léan A.

Mol Cell Biochem. 1992 Oct 7;115(2):203-11.

PMID:
1280321
48.

Interactions between hypertension and diabetes on vascular function and structure in rats.

Tilton RG, Pugliese G, Faller AM, LaRose LS, Province MA, Williamson JR.

J Diabetes Complications. 1992 Jul-Sep;6(3):187-96.

PMID:
1472745
49.

Production of polyclonal antibody to the bovine adrenal atrial natriuretic factor-R1 receptor.

Rondeau JJ, McNicoll N, Lord C, Larose L, Meloche S, Gagnon J, Ong H, De Léan A.

J Recept Res. 1992;12(4):485-505.

PMID:
1281231
50.

Discordant effects of the aldose reductase inhibitor, sorbinil, on vascular structure and function in chronically diabetic and galactosemic rats.

Tilton RG, Pugliese G, LaRose LS, Faller AM, Chang K, Province MA, Williamson JR.

J Diabet Complications. 1991 Oct-Dec;5(4):230-7.

PMID:
1779018

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