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Items: 20


Efficient measurement and factorization of high-order drug interactions in Mycobacterium tuberculosis.

Cokol M, Kuru N, Bicak E, Larkins-Ford J, Aldridge BB.

Sci Adv. 2017 Oct 11;3(10):e1701881. doi: 10.1126/sciadv.1701881. eCollection 2017 Oct.


Selective Degradation of Host RNA Polymerase II Transcripts by Influenza A Virus PA-X Host Shutoff Protein.

Khaperskyy DA, Schmaling S, Larkins-Ford J, McCormick C, Gaglia MM.

PLoS Pathog. 2016 Feb 5;12(2):e1005427. doi: 10.1371/journal.ppat.1005427. eCollection 2016 Feb.


On the Mechanism of Berberine-INF55 (5-Nitro-2-phenylindole) Hybrid Antibacterials.

Dolla NK, Chen C, Larkins-Ford J, Rajamuthiah R, Jagadeesan S, Conery AL, Ausubel FM, Mylonakis E, Bremner JB, Lewis K, Kelso MJ.

Aust J Chem. 2015;67:1471-1480.


Lipid signalling couples translational surveillance to systemic detoxification in Caenorhabditis elegans.

Govindan JA, Jayamani E, Zhang X, Breen P, Larkins-Ford J, Mylonakis E, Ruvkun G.

Nat Cell Biol. 2015 Oct;17(10):1294-303. doi: 10.1038/ncb3229. Epub 2015 Aug 31.


A new antibiotic with potent activity targets MscL.

Iscla I, Wray R, Blount P, Larkins-Ford J, Conery AL, Ausubel FM, Ramu S, Kavanagh A, Huang JX, Blaskovich MA, Cooper MA, Obregon-Henao A, Orme I, Tjandra ES, Stroeher UH, Brown MH, Macardle C, van Holst N, Ling Tong C, Slattery AD, Gibson CT, Raston CL, Boulos RA.

J Antibiot (Tokyo). 2015 Jul;68(7):453-62. doi: 10.1038/ja.2015.4. Epub 2015 Feb 4.


Insect-derived cecropins display activity against Acinetobacter baumannii in a whole-animal high-throughput Caenorhabditis elegans model.

Jayamani E, Rajamuthiah R, Larkins-Ford J, Fuchs BB, Conery AL, Vilcinskas A, Ausubel FM, Mylonakis E.

Antimicrob Agents Chemother. 2015 Mar;59(3):1728-37. doi: 10.1128/AAC.04198-14. Epub 2015 Jan 12.


High- and low-throughput scoring of fat mass and body fat distribution in C. elegans.

Wählby C, Conery AL, Bray MA, Kamentsky L, Larkins-Ford J, Sokolnicki KL, Veneskey M, Michaels K, Carpenter AE, O'Rourke EJ.

Methods. 2014 Aug 1;68(3):492-9. doi: 10.1016/j.ymeth.2014.04.017. Epub 2014 Apr 28.


High-throughput screening for novel anti-infectives using a C. elegans pathogenesis model.

Conery AL, Larkins-Ford J, Ausubel FM, Kirienko NV.

Curr Protoc Chem Biol. 2014 Mar 14;6(1):25-37. doi: 10.1002/9780470559277.ch130160.


Whole animal automated platform for drug discovery against multi-drug resistant Staphylococcus aureus.

Rajamuthiah R, Fuchs BB, Jayamani E, Kim Y, Larkins-Ford J, Conery A, Ausubel FM, Mylonakis E.

PLoS One. 2014 Feb 19;9(2):e89189. doi: 10.1371/journal.pone.0089189. eCollection 2014.


Pseudomonas aeruginosa disrupts Caenorhabditis elegans iron homeostasis, causing a hypoxic response and death.

Kirienko NV, Kirienko DR, Larkins-Ford J, Wählby C, Ruvkun G, Ausubel FM.

Cell Host Microbe. 2013 Apr 17;13(4):406-16. doi: 10.1016/j.chom.2013.03.003.


Stimulation of host immune defenses by a small molecule protects C. elegans from bacterial infection.

Pukkila-Worley R, Feinbaum R, Kirienko NV, Larkins-Ford J, Conery AL, Ausubel FM.

PLoS Genet. 2012;8(6):e1002733. doi: 10.1371/journal.pgen.1002733. Epub 2012 Jun 14.


C. elegans Notch signaling regulates adult chemosensory response and larval molting quiescence.

Singh K, Chao MY, Somers GA, Komatsu H, Corkins ME, Larkins-Ford J, Tucey T, Dionne HM, Walsh MB, Beaumont EK, Hart DP, Lockery SR, Hart AC.

Curr Biol. 2011 May 24;21(10):825-34. doi: 10.1016/j.cub.2011.04.010. Epub 2011 May 5.


Berberine-INF55 (5-nitro-2-phenylindole) hybrid antimicrobials: effects of varying the relative orientation of the berberine and INF55 components.

Tomkiewicz D, Casadei G, Larkins-Ford J, Moy TI, Garner J, Bremner JB, Ausubel FM, Lewis K, Kelso MJ.

Antimicrob Agents Chemother. 2010 Aug;54(8):3219-24. doi: 10.1128/AAC.01715-09. Epub 2010 May 24.


Identification of antifungal compounds active against Candida albicans using an improved high-throughput Caenorhabditis elegans assay.

Okoli I, Coleman JJ, Tampakakis E, An WF, Holson E, Wagner F, Conery AL, Larkins-Ford J, Wu G, Stern A, Ausubel FM, Mylonakis E.

PLoS One. 2009 Sep 14;4(9):e7025. doi: 10.1371/journal.pone.0007025. Erratum in: PLoS One. 2010;5(4) doi:10.1371/annotation/76699885-a47e-426c-accd-35576696c4f2.. Tempakakis, Emmanouil [corrected to Tampakakis, Emmanouil].


High-throughput screen for novel antimicrobials using a whole animal infection model.

Moy TI, Conery AL, Larkins-Ford J, Wu G, Mazitschek R, Casadei G, Lewis K, Carpenter AE, Ausubel FM.

ACS Chem Biol. 2009 Jul 17;4(7):527-33. doi: 10.1021/cb900084v.


OSM-11 facilitates LIN-12 Notch signaling during Caenorhabditis elegans vulval development.

Komatsu H, Chao MY, Larkins-Ford J, Corkins ME, Somers GA, Tucey T, Dionne HM, White JQ, Wani K, Boxem M, Hart AC.

PLoS Biol. 2008 Aug 12;6(8):e196. doi: 10.1371/journal.pbio.0060196.


Sexual and social stimuli elicit rapid and contrasting genomic responses.

Cummings ME, Larkins-Ford J, Reilly CR, Wong RY, Ramsey M, Hofmann HA.

Proc Biol Sci. 2008 Feb 22;275(1633):393-402.


Efficacy of RNA amplification is dependent on sequence characteristics: implications for gene expression profiling using a cDNA microarray.

Duftner N, Larkins-Ford J, Legendre M, Hofmann HA.

Genomics. 2008 Jan;91(1):108-17. Epub 2007 Nov 14.


lin-12 Notch functions in the adult nervous system of C. elegans.

Chao MY, Larkins-Ford J, Tucey TM, Hart AC.

BMC Neurosci. 2005 Jul 12;6:45.


Diversity in the structure of electrocommunication signals within a genus of electric fish, Apteronotus.

Dunlap KD, Larkins-Ford J.

J Comp Physiol A Neuroethol Sens Neural Behav Physiol. 2003 Feb;189(2):153-61. Epub 2003 Feb 7.


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