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Items: 1 to 50 of 762

1.

Impairment of trophoblast survival and differentiation by LXR ligands is prevented by cholesterol but not ABCA1 silencing.

Harmon CM, McGonigal S, Larkin JC.

Placenta. 2018 Sep;69:50-56. doi: 10.1016/j.placenta.2018.07.003. Epub 2018 Jul 10.

PMID:
30213484
2.

I'll say this only once.

Larkin J.

Scott Med J. 2018 Sep 11:36933018801174. doi: 10.1177/0036933018801174. [Epub ahead of print] No abstract available.

PMID:
30205769
3.

The impact of effective systemic therapies on surgery for stage IV melanoma.

Smith MJF, Smith HG, Joshi K, Gore M, Strauss DC, Hayes AJ, Larkin J.

Eur J Cancer. 2018 Sep 6;103:24-31. doi: 10.1016/j.ejca.2018.08.008. [Epub ahead of print]

PMID:
30196107
4.

Immune checkpoint inhibitors and cardiovascular toxicity.

Lyon AR, Yousaf N, Battisti NML, Moslehi J, Larkin J.

Lancet Oncol. 2018 Sep;19(9):e447-e458. doi: 10.1016/S1470-2045(18)30457-1. Review.

PMID:
30191849
5.

Anti-PD-1 monotherapy versus anti-PD1 plus anti-CTLA4 in advanced melanoma: how do we decide?

Au L, O'Reilly A, Larkin J.

Melanoma Manag. 2017 Sep;4(3):151-155. doi: 10.2217/mmt-2017-0016. Epub 2017 Aug 2. No abstract available.

6.

Immunotherapy for Melanoma Metastatic to the Brain.

Turajlic S, Larkin J.

N Engl J Med. 2018 Aug 23;379(8):789-790. doi: 10.1056/NEJMe1807752. No abstract available.

PMID:
30134137
7.

Sodium and Potassium Intake: Effects on Chronic Disease Outcomes and Risks [Internet].

Newberry SJ, Chung M, Anderson CAM, Chen C, Fu Z, Tang A, Zhao N, Booth M, Marks J, Hollands S, Motala A, Larkin J, Shanman R, Hempel S.

Rockville (MD): Agency for Healthcare Research and Quality (US); 2018 Jun.

8.

A spatiotemporal DNA endoploidy map of the Arabidopsis root reveals roles for the endocycle in root development and stress adaptation.

Bhosale R, Boudolf V, Cuevas F, Lu R, Eekhout T, Hu Z, van Isterdael G, Lambert G, Xu F, Nowack MK, Smith RS, Vercauteren I, De Rycke RM, Storme V, Beeckman T, Larkin JC, Kremer A, Höfte H, Galbraith DW, Kumpf RP, Maere S, De Veylder L.

Plant Cell. 2018 Aug 16. pii: tpc.00983.2017. doi: 10.1105/tpc.17.00983. [Epub ahead of print]

PMID:
30115738
9.

Optimization of molecularly targeted MRI in the brain: empirical comparison of sequences and particles.

Zarghami N, Khrapitchev AA, Perez-Balderas F, Soto MS, Larkin JR, Bau L, Sibson NR.

Int J Nanomedicine. 2018 Jul 25;13:4345-4359. doi: 10.2147/IJN.S158071. eCollection 2018.

10.

Modeled Prognostic Subgroups for Survival and Treatment Outcomes in BRAF V600-Mutated Metastatic Melanoma: Pooled Analysis of 4 Randomized Clinical Trials.

Hauschild A, Larkin J, Ribas A, Dréno B, Flaherty KT, Ascierto PA, Lewis KD, McKenna E, Zhu Q, Mun Y, McArthur GA.

JAMA Oncol. 2018 Aug 2. doi: 10.1001/jamaoncol.2018.2668. [Epub ahead of print]

PMID:
30073321
11.

Signal Percolation within a Bacterial Community.

Larkin JW, Zhai X, Kikuchi K, Redford SE, Prindle A, Liu J, Greenfield S, Walczak AM, Garcia-Ojalvo J, Mugler A, Süel GM.

Cell Syst. 2018 Aug 22;7(2):137-145.e3. doi: 10.1016/j.cels.2018.06.005. Epub 2018 Jul 25.

12.

Elusive search for effective provider interventions: a systematic review of provider interventions to increase adherence to evidence-based treatment for depression.

Pedersen ER, Rubenstein L, Kandrack R, Danz M, Belsher B, Motala A, Booth M, Larkin J, Hempel S.

Implement Sci. 2018 Jul 20;13(1):99. doi: 10.1186/s13012-018-0788-8. Review.

13.

Immune-checkpoint inhibitors in melanoma and kidney cancer: from sequencing to rational selection.

Flynn M, Pickering L, Larkin J, Turajlic S.

Ther Adv Med Oncol. 2018 Jun 12;10:1758835918777427. doi: 10.1177/1758835918777427. eCollection 2018. Review.

14.

Brave new world.

Larkin J.

Scott Med J. 2018 Feb;63(1):1-2. doi: 10.1177/0036933018784173. No abstract available.

PMID:
29956603
15.

Doctors, negligence and the GMC.

Larkin J.

Scott Med J. 2018 May;63(2):35-37. doi: 10.1177/0036933018784174. Epub 2018 Jun 26. No abstract available.

PMID:
29945492
16.

SOCIETY FOR ENDOCRINOLOGY ENDOCRINE EMERGENCY GUIDANCE: Acute management of the endocrine complications of checkpoint inhibitor therapy.

Higham CE, Olsson-Brown A, Carroll P, Cooksley T, Larkin J, Lorigan P, Morganstein D, Trainer PJ; Society for Endocrinology Clinical Committee.

Endocr Connect. 2018 Jul;7(7):G1-G7. doi: 10.1530/EC-18-0068.

17.

Management of toxicities from immunotherapy: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Haanen JBAG, Carbonnel F, Robert C, Kerr KM, Peters S, Larkin J, Jordan K; ESMO Guidelines Committee.

Ann Oncol. 2018 Jun 15. doi: 10.1093/annonc/mdy162. [Epub ahead of print] No abstract available.

PMID:
29917046
18.

Association of Smoking Status With Mortality and Hospitalization in Hemodialysis Patients.

Li NC, Thadhani RI, Reviriego-Mendoza M, Larkin JW, Maddux FW, Ofsthun NJ.

Am J Kidney Dis. 2018 Jun 14. pii: S0272-6386(18)30641-3. doi: 10.1053/j.ajkd.2018.04.004. [Epub ahead of print]

PMID:
29909936
19.

Functional Analysis of Short Linear Motifs in the Plant Cyclin-Dependent Kinase Inhibitor SIAMESE.

Kumar N, Dale R, Kemboi D, Zeringue EA, Kato N, Larkin JC.

Plant Physiol. 2018 Aug;177(4):1569-1579. doi: 10.1104/pp.18.00147. Epub 2018 Jun 14.

20.

Corrigendum re "Genetic Variants Related to Longer Telomere Length are Associated with Increased Risk of Renal Cell Carcinoma" [Eur Urol 2017;72:747-54].

Machiela MJ, Hofmann JN, Carreras-Torres R, Brown KM, Johansson M, Wang Z, Foll M, Li P, Rothman N, Savage SA, Gaborieau V, McKay JD, Ye Y, Henrion M, Bruinsma F, Jordan S, Severi G, Hveem K, Vatten LJ, Fletcher T, Koppova K, Larsson SC, Wolk A, Banks RE, Selby PJ, Easton DF, Pharoah P, Andreotti G, Freeman LEB, Koutros S, Albanes D, Mannisto S, Weinstein S, Clark PE, Edwards TE, Lipworth L, Gapstur SM, Stevens VL, Carol H, Freedman ML, Pomerantz MM, Cho E, Kraft P, Preston MA, Wilson KM, Gaziano JM, Sesso HS, Black A, Freedman ND, Huang WY, Anema JG, Kahnoski RJ, Lane BR, Noyes SL, Petillo D, Colli LM, Sampson JN, Besse C, Blanche H, Boland A, Burdette L, Prokhortchouk E, Skryabin KG, Yeager M, Mijuskovic M, Ognjanovic M, Foretova L, Holcatova I, Janout V, Mates D, Mukeriya A, Rascu S, Zaridze D, Bencko V, Cybulski C, Fabianova E, Jinga V, Lissowska J, Lubinski J, Navratilova M, Rudnai P, Szeszenia-Dabrowska N, Benhamou S, Cancel-Tassin G, Cussenot O, Bueno-de-Mesquita HBA, Canzian F, Duell EJ, Ljungberg B, Sitaram RT, Peters U, White E, Anderson GL, Johnson L, Luo J, Buring J, Lee IM, Chow WH, Moore LE, Wood C, Eisen T, Larkin J, Choueiri TK, Lathrop GM, Teh BT, Deleuze JF, Wu X, Houlston RS, Brennan P, Chanock SJ, Scelo G, Purdue MP.

Eur Urol. 2018 Sep;74(3):e85-e86. doi: 10.1016/j.eururo.2018.05.017. Epub 2018 May 28. No abstract available.

PMID:
29853305
21.

Adjuvant Vascular Endothelial Growth Factor-targeted Therapy in Renal Cell Carcinoma: A Systematic Review and Pooled Analysis.

Sun M, Marconi L, Eisen T, Escudier B, Giles RH, Haas NB, Harshman LC, Quinn DI, Larkin J, Pal SK, Powles T, Ryan CW, Sternberg CN, Uzzo R, Choueiri TK, Bex A.

Eur Urol. 2018 May 18. pii: S0302-2838(18)30349-X. doi: 10.1016/j.eururo.2018.05.002. [Epub ahead of print] Review.

PMID:
29784193
22.

Making Epidermal Bladder Cells Bigger: Developmental- and Salinity-Induced Endopolyploidy in a Model Halophyte.

Barkla BJ, Rhodes T, Tran KT, Wijesinghege C, Larkin JC, Dassanayake M.

Plant Physiol. 2018 Jun;177(2):615-632. doi: 10.1104/pp.18.00033. Epub 2018 May 3.

23.

Modal analysis of the thermal conductivity of nanowires: examining unique thermal transport features.

Samaraweera N, Larkin JM, Chan KL, Mithraratne K.

J Phys Condens Matter. 2018 Jun 6;30(22):225301. doi: 10.1088/1361-648X/aabe54. Epub 2018 Apr 16.

PMID:
29658884
24.

Adjuvant Pembrolizumab versus Placebo in Resected Stage III Melanoma.

Eggermont AMM, Blank CU, Mandala M, Long GV, Atkinson V, Dalle S, Haydon A, Lichinitser M, Khattak A, Carlino MS, Sandhu S, Larkin J, Puig S, Ascierto PA, Rutkowski P, Schadendorf D, Koornstra R, Hernandez-Aya L, Maio M, van den Eertwegh AJM, Grob JJ, Gutzmer R, Jamal R, Lorigan P, Ibrahim N, Marreaud S, van Akkooi ACJ, Suciu S, Robert C.

N Engl J Med. 2018 May 10;378(19):1789-1801. doi: 10.1056/NEJMoa1802357. Epub 2018 Apr 15.

PMID:
29658430
25.

Tracking Cancer Evolution Reveals Constrained Routes to Metastases: TRACERx Renal.

Turajlic S, Xu H, Litchfield K, Rowan A, Chambers T, Lopez JI, Nicol D, O'Brien T, Larkin J, Horswell S, Stares M, Au L, Jamal-Hanjani M, Challacombe B, Chandra A, Hazell S, Eichler-Jonsson C, Soultati A, Chowdhury S, Rudman S, Lynch J, Fernando A, Stamp G, Nye E, Jabbar F, Spain L, Lall S, Guarch R, Falzon M, Proctor I, Pickering L, Gore M, Watkins TBK, Ward S, Stewart A, DiNatale R, Becerra MF, Reznik E, Hsieh JJ, Richmond TA, Mayhew GF, Hill SM, McNally CD, Jones C, Rosenbaum H, Stanislaw S, Burgess DL, Alexander NR, Swanton C; PEACE; TRACERx Renal Consortium.

Cell. 2018 Apr 19;173(3):581-594.e12. doi: 10.1016/j.cell.2018.03.057. Epub 2018 Apr 12.

26.

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal.

Turajlic S, Xu H, Litchfield K, Rowan A, Horswell S, Chambers T, O'Brien T, Lopez JI, Watkins TBK, Nicol D, Stares M, Challacombe B, Hazell S, Chandra A, Mitchell TJ, Au L, Eichler-Jonsson C, Jabbar F, Soultati A, Chowdhury S, Rudman S, Lynch J, Fernando A, Stamp G, Nye E, Stewart A, Xing W, Smith JC, Escudero M, Huffman A, Matthews N, Elgar G, Phillimore B, Costa M, Begum S, Ward S, Salm M, Boeing S, Fisher R, Spain L, Navas C, Grönroos E, Hobor S, Sharma S, Aurangzeb I, Lall S, Polson A, Varia M, Horsfield C, Fotiadis N, Pickering L, Schwarz RF, Silva B, Herrero J, Luscombe NM, Jamal-Hanjani M, Rosenthal R, Birkbak NJ, Wilson GA, Pipek O, Ribli D, Krzystanek M, Csabai I, Szallasi Z, Gore M, McGranahan N, Van Loo P, Campbell P, Larkin J, Swanton C; TRACERx Renal Consortium.

Cell. 2018 Apr 19;173(3):595-610.e11. doi: 10.1016/j.cell.2018.03.043. Epub 2018 Apr 12.

27.

Timing the Landmark Events in the Evolution of Clear Cell Renal Cell Cancer: TRACERx Renal.

Mitchell TJ, Turajlic S, Rowan A, Nicol D, Farmery JHR, O'Brien T, Martincorena I, Tarpey P, Angelopoulos N, Yates LR, Butler AP, Raine K, Stewart GD, Challacombe B, Fernando A, Lopez JI, Hazell S, Chandra A, Chowdhury S, Rudman S, Soultati A, Stamp G, Fotiadis N, Pickering L, Au L, Spain L, Lynch J, Stares M, Teague J, Maura F, Wedge DC, Horswell S, Chambers T, Litchfield K, Xu H, Stewart A, Elaidi R, Oudard S, McGranahan N, Csabai I, Gore M, Futreal PA, Larkin J, Lynch AG, Szallasi Z, Swanton C, Campbell PJ; TRACERx Renal Consortium.

Cell. 2018 Apr 19;173(3):611-623.e17. doi: 10.1016/j.cell.2018.02.020. Epub 2018 Apr 12.

28.

Are Digitally Delivered Psychological Interventions for Depression the Way Forward? A Review.

Stefanopoulou E, Lewis D, Taylor M, Broscombe J, Ahmad J, Larkin J.

Psychiatr Q. 2018 Apr 14. doi: 10.1007/s11126-018-9576-5. [Epub ahead of print] Review.

PMID:
29656348
29.

A Tale of Two Cycles.

Wang K, Larkin JC.

Dev Cell. 2018 Apr 9;45(1):8-9. doi: 10.1016/j.devcel.2018.03.016.

PMID:
29634938
30.

Effects of biological monitoring and results outreach on private landowner conservation management.

Lutter SH, Dayer AA, Heggenstaller E, Larkin JL.

PLoS One. 2018 Apr 4;13(4):e0194740. doi: 10.1371/journal.pone.0194740. eCollection 2018.

31.

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.

Arce Vargas F, Furness AJS, Litchfield K, Joshi K, Rosenthal R, Ghorani E, Solomon I, Lesko MH, Ruef N, Roddie C, Henry JY, Spain L, Ben Aissa A, Georgiou A, Wong YNS, Smith M, Strauss D, Hayes A, Nicol D, O'Brien T, Mårtensson L, Ljungars A, Teige I, Frendéus B; TRACERx Melanoma; TRACERx Renal; TRACERx Lung consortia, Pule M, Marafioti T, Gore M, Larkin J, Turajlic S, Swanton C, Peggs KS, Quezada SA.

Cancer Cell. 2018 Apr 9;33(4):649-663.e4. doi: 10.1016/j.ccell.2018.02.010. Epub 2018 Mar 22.

32.

Corrigendum to "Rechallenge with BRAF-directed treatment in metastatic melanoma: A multi-institutional retrospective study*" [Eur J Cancer 91 (2018) 116-124].

Valpione S, Carlino MS, Mangana J, Mooradian MJ, McArthur G, Schadendorf D, Hauschild A, Menzies AM, Arance A, Ascierto PA, Giacomo AD, de Rosa F, Larkin J, Park JJ, Goldinger SM, Sullivan RJ, Xu W, Livingstone E, Weichenthal M, Rai R, Gaba L, Long GV, Lorigan P.

Eur J Cancer. 2018 Apr;93:158. doi: 10.1016/j.ejca.2018.02.001. Epub 2018 Mar 13. No abstract available.

PMID:
29548533
33.

Contemporary outcomes from the use of regular imaging to detect relapse in high-risk cutaneous melanoma.

Lim KHJ, Spain L, Barker C, Georgiou A, Walls G, Gore M, Turajlic S, Board R, Larkin JM, Lorigan P.

ESMO Open. 2018 Feb 24;3(2):e000317. doi: 10.1136/esmoopen-2017-000317. eCollection 2018.

34.

Impact of issuing longer- versus shorter-duration prescriptions: a systematic review.

King S, Miani C, Exley J, Larkin J, Kirtley A, Payne RA.

Br J Gen Pract. 2018 Apr;68(669):e286-e292. doi: 10.3399/bjgp18X695501. Epub 2018 Mar 12.

PMID:
29530921
35.

Preliminary results for avelumab plus axitinib as first-line therapy in patients with advanced clear-cell renal-cell carcinoma (JAVELIN Renal 100): an open-label, dose-finding and dose-expansion, phase 1b trial.

Choueiri TK, Larkin J, Oya M, Thistlethwaite F, Martignoni M, Nathan P, Powles T, McDermott D, Robbins PB, Chism DD, Cho D, Atkins MB, Gordon MS, Gupta S, Uemura H, Tomita Y, Compagnoni A, Fowst C, di Pietro A, Rini BI.

Lancet Oncol. 2018 Apr;19(4):451-460. doi: 10.1016/S1470-2045(18)30107-4. Epub 2018 Mar 9.

PMID:
29530667
36.

Quantitative blood flow measurement in rat brain with multiphase arterial spin labelling magnetic resonance imaging.

Larkin JR, Simard MA, Khrapitchev AA, Meakin JA, Okell TW, Craig M, Ray KJ, Jezzard P, Chappell MA, Sibson NR.

J Cereb Blood Flow Metab. 2018 Mar 2:271678X18756218. doi: 10.1177/0271678X18756218. [Epub ahead of print]

PMID:
29498562
37.

Relationships between Neighborhood Walkability and Objectively Measured Physical Activity Levels in Hemodialysis Patients.

Han M, Ye X, Preciado P, Williams S, Campos I, Bonner M, Young C, Marsh D, Larkin JW, Usvyat LA, Maddux FW, Pecoits-Filho R, Kotanko P.

Blood Purif. 2018;45(1-3):236-244. doi: 10.1159/000485161. Epub 2018 Jan 26.

38.

BMI and outcomes in melanoma: more evidence for the obesity paradox.

Hayes AJ, Larkin J.

Lancet Oncol. 2018 Mar;19(3):269-270. doi: 10.1016/S1470-2045(18)30077-9. Epub 2018 Feb 12. No abstract available.

PMID:
29449191
39.

Health-related quality of life impact of cobimetinib in combination with vemurafenib in patients with advanced or metastatic BRAFV600 mutation-positive melanoma.

Dréno B, Ascierto PA, Atkinson V, Liszkay G, Maio M, Mandalà M, Demidov L, Stroyakovskiy D, Thomas L, de la Cruz-Merino L, Dutriaux C, Garbe C, Bartley K, Karagiannis T, Chang I, Rooney I, Koralek DO, Larkin J, McArthur GA, Ribas A.

Br J Cancer. 2018 Mar 20;118(6):777-784. doi: 10.1038/bjc.2017.488. Epub 2018 Feb 13.

40.

Depressive affect in incident hemodialysis patients.

McDougall KA, Larkin JW, Wingard RL, Jiao Y, Rosen S, Ma L, Usvyat LA, Maddux FW.

Clin Kidney J. 2018 Feb;11(1):123-129. doi: 10.1093/ckj/sfx054. Epub 2017 Jul 11.

41.

Pembrolizumab in Combination with Radiotherapy for Metastatic Melanoma - Introducing the PERM Trial.

Yip K, Melcher A, Harrington K, Illidge T, Nobes J, Webster A, Smith D, Lorigan P, Nathan P, Larkin J.

Clin Oncol (R Coll Radiol). 2018 Apr;30(4):201-203. doi: 10.1016/j.clon.2018.01.001. No abstract available.

PMID:
29402599
42.

Feather mite abundance varies but symbiotic nature of mite-host relationship does not differ between two ecologically dissimilar warblers.

Matthews AE, Larkin JL, Raybuck DW, Slevin MC, Stoleson SH, Boves TJ.

Ecol Evol. 2017 Dec 20;8(2):1227-1238. doi: 10.1002/ece3.3738. eCollection 2018 Jan.

43.

Monosubstituted Phenylboronic Acids, R-B(OH)2 (R = C6H5, C6H4CH3, C6H4NH2, C6H4OH, and C6H4F): A Computational Investigation.

Rao NZ, Larkin JD, Bock CW.

Struct Chem. 2017 Aug;28(4):945-955. doi: 10.1007/s11224-016-0897-4. Epub 2016 Dec 15.

44.

First report of overall survival for ipilimumab plus nivolumab from the phase III Checkmate 067 study in advanced melanoma.

Turajlic S, Gore M, Larkin J.

Ann Oncol. 2018 Mar 1;29(3):542-543. doi: 10.1093/annonc/mdy020. No abstract available.

PMID:
29360923
45.

Rechallenge with BRAF-directed treatment in metastatic melanoma: A multi-institutional retrospective study.

Valpione S, Carlino MS, Mangana J, Mooradian MJ, McArthur G, Schadendorf D, Hauschild A, Menzies AM, Arance A, Ascierto PA, Di Giacomo A, de Rosa F, Larkin J, Park JJ, Goldinger SM, Sullivan RJ, Xu W, Livingstone E, Weichenthal M, Rai R, Gaba L, Long GV, Lorigan P.

Eur J Cancer. 2018 Mar;91:116-124. doi: 10.1016/j.ejca.2017.12.007. Epub 2018 Jan 19. Erratum in: Eur J Cancer. 2018 Mar 13;:.

46.

Proliferative myositis of the latissimus dorsi presenting in a 20-year-old male athlete.

McHugh N, Tevlin R, Beggan C, Ryan DJ, Larkin J, Moloney F, Bennett MW, Kelly J.

Ir Med J. 2017 Aug 8;110(7):605.

PMID:
29341517
47.

Body Mapping as a Youth Sexual Health Intervention and Data Collection Tool.

Lys C, Gesink D, Strike C, Larkin J.

Qual Health Res. 2018 Jun;28(7):1185-1198. doi: 10.1177/1049732317750862. Epub 2018 Jan 5.

48.

Nivolumab and Ipilimumab in Advanced Melanoma.

Wolchok JD, Rollin L, Larkin J.

N Engl J Med. 2017 Dec 21;377(25):2503-2504. doi: 10.1056/NEJMc1714339. No abstract available.

49.

Effect of Population-Specific Birthweight Curves on Disparities in Perinatal Mortality in Small-for-Gestational Age Pregnancies.

Larkin JC, Naimi AI.

Am J Perinatol. 2018 Jun;35(7):695-702. doi: 10.1055/s-0037-1608791. Epub 2017 Dec 13.

PMID:
29237187
50.

Eighth American Joint Committee on Cancer (AJCC) melanoma classification: Let us reconsider stage III.

Grob JJ, Schadendorf D, Lorigan P, Ascierto P, Larkin J, Nathan P, Robert C, Hauschild A, Weber J, Daud A, Hamid O, Dummer R, Hansson J, Hoeller C, Schachter J, Van Akkooi ACJ, Garbe C.

Eur J Cancer. 2018 Mar;91:168-170. doi: 10.1016/j.ejca.2017.11.023. Epub 2017 Dec 7. No abstract available.

PMID:
29224903

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