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Items: 1 to 50 of 185

1.

A novel assay to screen siRNA libraries identifies protein kinases required for chromosome transmission.

Liskovykh M, Goncharov NV, Petrov N, Aksenova V, Pegoraro G, Ozbun LL, Reinhold WC, Varma S, Dasso M, Kumeiko V, Masumoto H, Earnshaw WC, Larionov V, Kouprina N.

Genome Res. 2019 Oct;29(10):1719-1732. doi: 10.1101/gr.254276.119. Epub 2019 Sep 12.

2.

Henry Reaction Revisited. Crucial Role of Water in an Asymmetric Henry Reaction Catalyzed by Chiral NNO-Type Copper(II) Complexes.

Larionov VA, Yashkina LV, Medvedev MG, Smol'yakov AF, Peregudov AS, Pavlov AA, Eremin DB, Savel'yeva TF, Maleev VI, Belokon YN.

Inorg Chem. 2019 Aug 19;58(16):11051-11065. doi: 10.1021/acs.inorgchem.9b01574. Epub 2019 Aug 1.

PMID:
31369247
3.

Human Artificial Chromosomes that Bypass Centromeric DNA.

Logsdon GA, Gambogi CW, Liskovykh MA, Barrey EJ, Larionov V, Miga KH, Heun P, Black BE.

Cell. 2019 Jul 25;178(3):624-639.e19. doi: 10.1016/j.cell.2019.06.006.

4.

TAR Cloning: Perspectives for Functional Genomics, Biomedicine, and Biotechnology.

Kouprina N, Larionov V.

Mol Ther Methods Clin Dev. 2019 May 21;14:16-26. doi: 10.1016/j.omtm.2019.05.006. eCollection 2019 Sep 13. Review.

5.

De novo formation and epigenetic maintenance of centromere chromatin.

Ohzeki J, Larionov V, Earnshaw WC, Masumoto H.

Curr Opin Cell Biol. 2019 Jun;58:15-25. doi: 10.1016/j.ceb.2018.12.004. Epub 2019 Jan 15. Review.

6.

Novel screen for anti-cancer drugs that elevate chromosome instability (CIN) using human artificial chromosome (HAC).

Kouprina N, Pommier Y, Larionov V.

Oncotarget. 2018 Dec 7;9(96):36833-36835. doi: 10.18632/oncotarget.26406. eCollection 2018 Dec 7.

7.

Transfer of Synthetic Human Chromosome into Human Induced Pluripotent Stem Cells for Biomedical Applications.

Sinenko SA, Skvortsova EV, Liskovykh MA, Ponomartsev SV, Kuzmin AA, Khudiakov AA, Malashicheva AB, Alenina N, Larionov V, Kouprina N, Tomilin AN.

Cells. 2018 Dec 8;7(12). pii: E261. doi: 10.3390/cells7120261.

8.

Interaction of a trinuclear copper(i) pyrazolate with alkynes and carbon-carbon triple bond activation.

Titov AA, Larionov VA, Smol'yakov AF, Godovikova MI, Titova EM, Maleev VI, Shubina ES.

Chem Commun (Camb). 2019 Jan 2;55(3):290-293. doi: 10.1039/c8cc08592g.

PMID:
30411109
9.

Kinetic Resolution of Epoxides with CO2 Catalyzed by a Chiral-at-Iridium Complex.

Qin J, Larionov VA, Harms K, Meggers E.

ChemSusChem. 2019 Jan 10;12(1):320-325. doi: 10.1002/cssc.201802049. Epub 2018 Nov 21.

PMID:
30324685
10.

Systematic Analysis of Compounds Specifically Targeting Telomeres and Telomerase for Clinical Implications in Cancer Therapy.

Lee HS, Carmena M, Liskovykh M, Peat E, Kim JH, Oshimura M, Masumoto H, Teulade-Fichou MP, Pommier Y, Earnshaw WC, Larionov V, Kouprina N.

Cancer Res. 2018 Nov 1;78(21):6282-6296. doi: 10.1158/0008-5472.CAN-18-0894. Epub 2018 Aug 30.

11.

Human Artificial Chromosome with Regulated Centromere: A Tool for Genome and Cancer Studies.

Kouprina N, Petrov N, Molina O, Liskovykh M, Pesenti E, Ohzeki JI, Masumoto H, Earnshaw WC, Larionov V.

ACS Synth Biol. 2018 Sep 21;7(9):1974-1989. doi: 10.1021/acssynbio.8b00230. Epub 2018 Aug 16. Review.

12.

Variation in human chromosome 21 ribosomal RNA genes characterized by TAR cloning and long-read sequencing.

Kim JH, Dilthey AT, Nagaraja R, Lee HS, Koren S, Dudekula D, Wood Iii WH, Piao Y, Ogurtsov AY, Utani K, Noskov VN, Shabalina SA, Schlessinger D, Phillippy AM, Larionov V.

Nucleic Acids Res. 2018 Jul 27;46(13):6712-6725. doi: 10.1093/nar/gky442.

13.

Analysis of the 9p21.3 sequence associated with coronary artery disease reveals a tendency for duplication in a CAD patient.

Kouprina N, Liskovykh M, Lee NCO, Noskov VN, Waterfall JJ, Walker RL, Meltzer PS, Topol EJ, Larionov V.

Oncotarget. 2018 Feb 26;9(20):15275-15291. doi: 10.18632/oncotarget.24567. eCollection 2018 Mar 16.

14.

Generation of a Synthetic Human Chromosome with Two Centromeric Domains for Advanced Epigenetic Engineering Studies.

Pesenti E, Kouprina N, Liskovykh M, Aurich-Costa J, Larionov V, Masumoto H, Earnshaw WC, Molina O.

ACS Synth Biol. 2018 Apr 20;7(4):1116-1130. doi: 10.1021/acssynbio.8b00018. Epub 2018 Mar 29.

15.

Blazar spectral variability as explained by a twisted inhomogeneous jet.

Raiteri CM, Villata M, Acosta-Pulido JA, Agudo I, Arkharov AA, Bachev R, Baida GV, Benítez E, Borman GA, Boschin W, Bozhilov V, Butuzova MS, Calcidese P, Carnerero MI, Carosati D, Casadio C, Castro-Segura N, Chen WP, Damljanovic G, D'Ammando F, Di Paola A, Echevarría J, Efimova NV, Ehgamberdiev SA, Espinosa C, Fuentes A, Giunta A, Gómez JL, Grishina TS, Gurwell MA, Hiriart D, Jermak H, Jordan B, Jorstad SG, Joshi M, Kopatskaya EN, Kuratov K, Kurtanidze OM, Kurtanidze SO, Lähteenmäki A, Larionov VM, Larionova EG, Larionova LV, Lázaro C, Lin CS, Malmrose MP, Marscher AP, Matsumoto K, McBreen B, Michel R, Mihov B, Minev M, Mirzaqulov DO, Mokrushina AA, Molina SN, Moody JW, Morozova DA, Nazarov SV, Nikolashvili MG, Ohlert JM, Okhmat DN, Ovcharov E, Pinna F, Polakis TA, Protasio C, Pursimo T, Redondo-Lorenzo FJ, Rizzi N, Rodriguez-Coira G, Sadakane K, Sadun AC, Samal MR, Savchenko SS, Semkov E, Skiff BA, Slavcheva-Mihova L, Smith PS, Steele IA, Strigachev A, Tammi J, Thum C, Tornikoski M, Troitskaya YV, Troitsky IS, Vasilyev AA, Vince O.

Nature. 2017 Dec 21;552(7685):374-377. doi: 10.1038/nature24623. Epub 2017 Dec 4.

PMID:
29211720
16.

Method to Assemble Genomic DNA Fragments or Genes on Human Artificial Chromosome with Regulated Kinetochore Using a Multi-Integrase System.

Lee NCO, Kim JH, Petrov NS, Lee HS, Masumoto H, Earnshaw WC, Larionov V, Kouprina N.

ACS Synth Biol. 2018 Jan 19;7(1):63-74. doi: 10.1021/acssynbio.7b00209. Epub 2017 Aug 24.

17.

Using human artificial chromosomes to study centromere assembly and function.

Molina O, Kouprina N, Masumoto H, Larionov V, Earnshaw WC.

Chromosoma. 2017 Oct;126(5):559-575. doi: 10.1007/s00412-017-0633-x. Epub 2017 Jul 7. Review.

PMID:
28688039
18.

Global histone modification fingerprinting in human cells using epigenetic reverse phase protein array.

Partolina M, Thoms HC, MacLeod KG, Rodriguez-Blanco G, Clarke MN, Venkatasubramani AV, Beesoo R, Larionov V, Neergheen-Bhujun VS, Serrels B, Kimura H, Carragher NO, Kagansky A.

Cell Death Discov. 2017 Mar 6;3:16077. doi: 10.1038/cddiscovery.2016.77. eCollection 2017.

19.

Epigenetic engineering reveals a balance between histone modifications and transcription in kinetochore maintenance.

Molina O, Vargiu G, Abad MA, Zhiteneva A, Jeyaprakash AA, Masumoto H, Kouprina N, Larionov V, Earnshaw WC.

Nat Commun. 2016 Nov 14;7:13334. doi: 10.1038/ncomms13334.

20.

3D-CLEM Reveals that a Major Portion of Mitotic Chromosomes Is Not Chromatin.

Booth DG, Beckett AJ, Molina O, Samejima I, Masumoto H, Kouprina N, Larionov V, Prior IA, Earnshaw WC.

Mol Cell. 2016 Nov 17;64(4):790-802. doi: 10.1016/j.molcel.2016.10.009. Epub 2016 Nov 10.

21.

Overexpression screens identify conserved dosage chromosome instability genes in yeast and human cancer.

Duffy S, Fam HK, Wang YK, Styles EB, Kim JH, Ang JS, Singh T, Larionov V, Shah SP, Andrews B, Boerkoel CF, Hieter P.

Proc Natl Acad Sci U S A. 2016 Sep 6;113(36):9967-76. doi: 10.1073/pnas.1611839113. Epub 2016 Aug 22.

22.

A polymorphic minisatellite region of BORIS regulates gene expression and its rare variants correlate with lung cancer susceptibility.

Yoon SL, Roh YG, Chu IS, Heo J, Kim SI, Chang H, Kang TH, Chung JW, Koh SS, Larionov V, Leem SH.

Exp Mol Med. 2016 Jul 15;48(7):e246. doi: 10.1038/emm.2016.50.

23.

Moving toward a higher efficiency of microcell-mediated chromosome transfer.

Liskovykh M, Lee NC, Larionov V, Kouprina N.

Mol Ther Methods Clin Dev. 2016 Jun 22;3:16043. doi: 10.1038/mtm.2016.43. eCollection 2016.

24.

KAT7/HBO1/MYST2 Regulates CENP-A Chromatin Assembly by Antagonizing Suv39h1-Mediated Centromere Inactivation.

Ohzeki J, Shono N, Otake K, Martins NM, Kugou K, Kimura H, Nagase T, Larionov V, Earnshaw WC, Masumoto H.

Dev Cell. 2016 Jun 6;37(5):413-27. doi: 10.1016/j.devcel.2016.05.006.

25.

Transformation-associated recombination (TAR) cloning for genomics studies and synthetic biology.

Kouprina N, Larionov V.

Chromosoma. 2016 Sep;125(4):621-32. doi: 10.1007/s00412-016-0588-3. Epub 2016 Apr 26. Review.

26.

Quantitative assessment of chromosome instability induced through chemical disruption of mitotic progression.

Markossian S, Arnaoutov A, Saba NS, Larionov V, Dasso M.

Cell Cycle. 2016 Jul 2;15(13):1706-14. doi: 10.1080/15384101.2016.1175796. Epub 2016 Apr 22.

27.

Development of a novel HAC-based "gain of signal" quantitative assay for measuring chromosome instability (CIN) in cancer cells.

Kim JH, Lee HS, Lee NC, Goncharov NV, Kumeiko V, Masumoto H, Earnshaw WC, Kouprina N, Larionov V.

Oncotarget. 2016 Mar 22;7(12):14841-56. doi: 10.18632/oncotarget.7854.

28.

Physical-chemical properties and the reactivity of pyridoxine and pyrrolidone carboxylate and their protolytic forms.

Golovenko NY, Larionov VB, Karpova OV.

Ukr Biochem J. 2016 Mar-Apr;88(2):73-81. doi: 10.15407/ubj88.02.073.

PMID:
29227608
29.

Effects of Anticancer Drugs on Chromosome Instability and New Clinical Implications for Tumor-Suppressing Therapies.

Lee HS, Lee NC, Kouprina N, Kim JH, Kagansky A, Bates S, Trepel JB, Pommier Y, Sackett D, Larionov V.

Cancer Res. 2016 Feb 15;76(4):902-11. doi: 10.1158/0008-5472.CAN-15-1617. Epub 2016 Feb 2.

30.

Chiral Cobalt(III) Complexes as Bifunctional Brønsted Acid-Lewis Base Catalysts for the Preparation of Cyclic Organic Carbonates.

Rulev YA, Larionov VA, Lokutova AV, Moskalenko MA, Lependina OL, Maleev VI, North M, Belokon YN.

ChemSusChem. 2016 Jan;9(2):216-22. doi: 10.1002/cssc.201501365. Epub 2015 Dec 14.

PMID:
26663897
31.

Epigenetic engineering shows that a human centromere resists silencing mediated by H3K27me3/K9me3.

Martins NM, Bergmann JH, Shono N, Kimura H, Larionov V, Masumoto H, Earnshaw WC.

Mol Biol Cell. 2016 Jan 1;27(1):177-96. doi: 10.1091/mbc.E15-08-0605. Epub 2015 Nov 12.

32.

CENP-C and CENP-I are key connecting factors for kinetochore and CENP-A assembly.

Shono N, Ohzeki J, Otake K, Martins NM, Nagase T, Kimura H, Larionov V, Earnshaw WC, Masumoto H.

J Cell Sci. 2015 Dec 15;128(24):4572-87. doi: 10.1242/jcs.180786. Epub 2015 Nov 2.

33.

Stable complex formation of CENP-B with the CENP-A nucleosome.

Fujita R, Otake K, Arimura Y, Horikoshi N, Miya Y, Shiga T, Osakabe A, Tachiwana H, Ohzeki J, Larionov V, Masumoto H, Kurumizaka H.

Nucleic Acids Res. 2015 May 26;43(10):4909-22. doi: 10.1093/nar/gkv405. Epub 2015 Apr 27.

34.

Generation of a conditionally self-eliminating HAC gene delivery vector through incorporation of a tTAVP64 expression cassette.

Kononenko AV, Lee NC, Liskovykh M, Masumoto H, Earnshaw WC, Larionov V, Kouprina N.

Nucleic Acids Res. 2015 May 19;43(9):e57. doi: 10.1093/nar/gkv124. Epub 2015 Feb 20.

35.

Stable maintenance of de novo assembled human artificial chromosomes in embryonic stem cells and their differentiated progeny in mice.

Liskovykh M, Ponomartsev S, Popova E, Bader M, Kouprina N, Larionov V, Alenina N, Tomilin A.

Cell Cycle. 2015;14(8):1268-73. doi: 10.1080/15384101.2015.1014151.

36.

Highly efficient CRISPR/Cas9-mediated TAR cloning of genes and chromosomal loci from complex genomes in yeast.

Lee NC, Larionov V, Kouprina N.

Nucleic Acids Res. 2015 Apr 30;43(8):e55. doi: 10.1093/nar/gkv112. Epub 2015 Feb 17.

37.

Genetic and epigenetic regulation of centromeres: a look at HAC formation.

Ohzeki J, Larionov V, Earnshaw WC, Masumoto H.

Chromosome Res. 2015 Feb;23(1):87-103. doi: 10.1007/s10577-015-9470-z. Review.

PMID:
25682171
38.

Recent advances in chromosome engineering.

Kouprina N, Larionov V.

Chromosome Res. 2015 Feb;23(1):1-5. doi: 10.1007/s10577-015-9469-5. No abstract available.

39.

[Kinetics of hydrolysis of 1,4-benzodiazepine derivative by carboxylesterases in mice organism].

Holovenko MIa, Larionov VB.

Ukr Biochem J. 2014 Jul-Aug;86(4):150-7. Ukrainian.

PMID:
25509194
40.

A portable BRCA1-HAC (human artificial chromosome) module for analysis of BRCA1 tumor suppressor function.

Kononenko AV, Bansal R, Lee NC, Grimes BR, Masumoto H, Earnshaw WC, Larionov V, Kouprina N.

Nucleic Acids Res. 2014 Dec 1;42(21). doi: 10.1093/nar/gku870. Epub 2014 Sep 26.

41.

From selective full-length genes isolation by TAR cloning in yeast to their expression from HAC vectors in human cells.

Kouprina N, Lee NC, Kononenko AV, Samoshkin A, Larionov V.

Methods Mol Biol. 2015;1227:3-26. doi: 10.1007/978-1-4939-1652-8_1.

PMID:
25239739
42.

Replication of alpha-satellite DNA arrays in endogenous human centromeric regions and in human artificial chromosome.

Erliandri I, Fu H, Nakano M, Kim JH, Miga KH, Liskovykh M, Earnshaw WC, Masumoto H, Kouprina N, Aladjem MI, Larionov V.

Nucleic Acids Res. 2014 Oct;42(18):11502-16. doi: 10.1093/nar/gku835. Epub 2014 Sep 16.

43.

Bi-HAC vector system toward gene and cell therapy.

Iida Y, Kazuki Y, Hayashi M, Ueda Y, Hasegawa M, Kouprina N, Larionov V, Oshimura M.

ACS Synth Biol. 2014 Feb 21;3(2):83-90. doi: 10.1021/sb400166j. Epub 2014 Jan 9.

44.

[Peculiarities of hypnotic effect and pharmacokinetics of hemisuccinate 3-hydroxyphenazepam (levana)].

Voronina TA, Larionov VB, Golovenko NIa, Nerobkova LN.

Eksp Klin Farmakol. 2014;77(1):3-6. Russian.

PMID:
24649593
45.

Human artificial chromosome-based gene delivery vectors for biomedicine and biotechnology.

Kouprina N, Tomilin AN, Masumoto H, Earnshaw WC, Larionov V.

Expert Opin Drug Deliv. 2014 Apr;11(4):517-35. doi: 10.1517/17425247.2014.882314. Epub 2014 Jan 30. Review.

PMID:
24479793
46.

A new assay for measuring chromosome instability (CIN) and identification of drugs that elevate CIN in cancer cells.

Lee HS, Lee NC, Grimes BR, Samoshkin A, Kononenko AV, Bansal R, Masumoto H, Earnshaw WC, Kouprina N, Larionov V.

BMC Cancer. 2013 May 22;13:252. doi: 10.1186/1471-2407-13-252.

47.

Protecting a transgene expression from the HAC-based vector by different chromatin insulators.

Lee NC, Kononenko AV, Lee HS, Tolkunova EN, Liskovykh MA, Masumoto H, Earnshaw WC, Tomilin AN, Larionov V, Kouprina N.

Cell Mol Life Sci. 2013 Oct;70(19):3723-37. doi: 10.1007/s00018-013-1362-9. Epub 2013 May 16.

48.

Re-engineering an alphoid(tetO)-HAC-based vector to enable high-throughput analyses of gene function.

Kononenko AV, Lee NC, Earnshaw WC, Kouprina N, Larionov V.

Nucleic Acids Res. 2013 May 1;41(10):e107. doi: 10.1093/nar/gkt205. Epub 2013 Apr 4.

49.

Organization of synthetic alphoid DNA array in human artificial chromosome (HAC) with a conditional centromere.

Kouprina N, Samoshkin A, Erliandri I, Nakano M, Lee HS, Fu H, Iida Y, Aladjem M, Oshimura M, Masumoto H, Earnshaw WC, Larionov V.

ACS Synth Biol. 2012 Dec 21;1(12):590-601.

50.

Nap1 regulates proper CENP-B binding to nucleosomes.

Tachiwana H, Miya Y, Shono N, Ohzeki J, Osakabe A, Otake K, Larionov V, Earnshaw WC, Kimura H, Masumoto H, Kurumizaka H.

Nucleic Acids Res. 2013 Mar 1;41(5):2869-80. doi: 10.1093/nar/gks1464. Epub 2013 Jan 15.

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