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Items: 1 to 50 of 217

1.

Evolution of the Muscarinic Acetylcholine Receptors in Vertebrates.

Pedersen JE, Bergqvist CA, Larhammar D.

eNeuro. 2018 Nov 8;5(5). pii: ENEURO.0340-18.2018. doi: 10.1523/ENEURO.0340-18.2018. eCollection 2018 Sep-Oct.

2.

Correction: Evolution of neuropeptide signalling systems (doi:10.1242/jeb.151092).

Elphick MR, Mirabeau O, Larhammar D.

J Exp Biol. 2018 Oct 10;221(Pt 19). pii: jeb193342. doi: 10.1242/jeb.193342. No abstract available.

3.

The Neuropeptide Y System Regulates Both Mechanical and Histaminergic Itch.

Gao T, Ma H, Xu B, Bergman J, Larhammar D, Lagerström MC.

J Invest Dermatol. 2018 Nov;138(11):2405-2411. doi: 10.1016/j.jid.2018.05.008. Epub 2018 May 24.

4.

Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor.

Yang Z, Han S, Keller M, Kaiser A, Bender BJ, Bosse M, Burkert K, Kögler LM, Wifling D, Bernhardt G, Plank N, Littmann T, Schmidt P, Yi C, Li B, Ye S, Zhang R, Xu B, Larhammar D, Stevens RC, Huster D, Meiler J, Zhao Q, Beck-Sickinger AG, Buschauer A, Wu B.

Nature. 2018 Apr;556(7702):520-524. doi: 10.1038/s41586-018-0046-x. Epub 2018 Apr 18.

5.

Copy number of pancreatic polypeptide receptor gene NPY4R correlates with body mass index and waist circumference.

Shebanits K, Andersson-Assarsson JC, Larsson I, Carlsson LMS, Feuk L, Larhammar D.

PLoS One. 2018 Apr 5;13(4):e0194668. doi: 10.1371/journal.pone.0194668. eCollection 2018.

6.

Evolution of neuropeptide signalling systems.

Elphick MR, Mirabeau O, Larhammar D.

J Exp Biol. 2018 Feb 9;221(Pt 3). pii: jeb151092. doi: 10.1242/jeb.151092. Review. Erratum in: J Exp Biol. 2018 Oct 10;221(Pt 19):.

7.

Elucidation of the Binding Mode of the Carboxyterminal Region of Peptide YY to the Human Y2 Receptor.

Xu B, Vasile S, Østergaard S, Paulsson JF, Pruner J, Åqvist J, Wulff BS, Gutiérrez-de-Terán H, Larhammar D.

Mol Pharmacol. 2018 Apr;93(4):323-334. doi: 10.1124/mol.117.110627. Epub 2018 Jan 24.

PMID:
29367257
8.

Evolution of the growth hormone, prolactin, prolactin 2 and somatolactin family.

Ocampo Daza D, Larhammar D.

Gen Comp Endocrinol. 2018 Aug 1;264:94-112. doi: 10.1016/j.ygcen.2018.01.007. Epub 2018 Jan 12.

PMID:
29339183
9.

Assessing and regulating homeopathic products.

Fears R, Griffin G, Larhammar D, Ter Meulen V, van der Meer JWM.

J Intern Med. 2017 Dec;282(6):563-565. doi: 10.1111/joim.12676. Epub 2017 Sep 25. No abstract available.

PMID:
28944510
10.

Evolution of the receptors for growth hormone, prolactin, erythropoietin and thrombopoietin in relation to the vertebrate tetraploidizations.

Ocampo Daza D, Larhammar D.

Gen Comp Endocrinol. 2018 Feb 1;257:143-160. doi: 10.1016/j.ygcen.2017.06.021. Epub 2017 Jun 23.

PMID:
28652136
11.

The Arg-Phe-amide peptide 26RFa/glutamine RF-amide peptide and its receptor: IUPHAR Review 24.

Leprince J, Bagnol D, Bureau R, Fukusumi S, Granata R, Hinuma S, Larhammar D, Primeaux S, Sopkova-de Oliveiras Santos J, Tsutsui K, Ukena K, Vaudry H.

Br J Pharmacol. 2017 Oct;174(20):3573-3607. doi: 10.1111/bph.13907. Epub 2017 Sep 8. Review.

12.

Evolution and expression of the phosphodiesterase 6 genes unveils vertebrate novelty to control photosensitivity.

Lagman D, Franzén IE, Eggert J, Larhammar D, Abalo XM.

BMC Evol Biol. 2016 Jun 13;16(1):124. doi: 10.1186/s12862-016-0695-z.

13.

Corticotropin-releasing hormone family evolution: five ancestral genes remain in some lineages.

Cardoso JC, Bergqvist CA, Félix RC, Larhammar D.

J Mol Endocrinol. 2016 Jul;57(1):73-86. doi: 10.1530/JME-16-0051. Epub 2016 May 24.

PMID:
27220618
14.

Neuropeptide Y family receptors Y1 and Y2 from sea lamprey, Petromyzon marinus.

Xu B, Lagman D, Sundström G, Larhammar D.

Gen Comp Endocrinol. 2015 Oct 1;222:106-15. doi: 10.1016/j.ygcen.2015.08.005. Epub 2015 Aug 6.

PMID:
26255155
15.

Transducin duplicates in the zebrafish retina and pineal complex: differential specialisation after the teleost tetraploidisation.

Lagman D, Callado-Pérez A, Franzén IE, Larhammar D, Abalo XM.

PLoS One. 2015 Mar 25;10(3):e0121330. doi: 10.1371/journal.pone.0121330. eCollection 2015.

16.

Ancestral vertebrate complexity of the opioid system.

Larhammar D, Bergqvist C, Sundström G.

Vitam Horm. 2015;97:95-122. doi: 10.1016/bs.vh.2014.11.001. Epub 2015 Jan 23. Review.

PMID:
25677769
17.

Characterization of peptide QRFP (26RFa) and its receptor from amphioxus, Branchiostoma floridae.

Xu B, Bergqvist CA, Sundström G, Lundell I, Vaudry H, Leprince J, Larhammar D.

Gen Comp Endocrinol. 2015 Jan 1;210:107-13. doi: 10.1016/j.ygcen.2014.10.010. Epub 2014 Oct 25.

PMID:
25449662
18.

Unexpected multiplicity of QRFP receptors in early vertebrate evolution.

Larhammar D, Xu B, Bergqvist CA.

Front Neurosci. 2014 Oct 24;8:337. doi: 10.3389/fnins.2014.00337. eCollection 2014.

19.

Comparative evolution of peptide hormone-binding GPCRs: a route to understanding functional complexity.

Cardoso JC, Larhammar D.

Gen Comp Endocrinol. 2014 Dec 1;209:1-2. doi: 10.1016/j.ygcen.2014.10.001. Epub 2014 Oct 7. No abstract available.

PMID:
25304823
20.

New insights into the evolution of vertebrate CRH (corticotropin-releasing hormone) and invertebrate DH44 (diuretic hormone 44) receptors in metazoans.

Cardoso JC, Félix RC, Bergqvist CA, Larhammar D.

Gen Comp Endocrinol. 2014 Dec 1;209:162-70. doi: 10.1016/j.ygcen.2014.09.004. Epub 2014 Sep 16. Review.

PMID:
25230393
21.

Turtle ghrelin.

Larhammar D, Lagman D.

Nat Genet. 2014 Jun;46(6):524-5. doi: 10.1038/ng.2960. No abstract available.

PMID:
24866184
22.

Neuropeptide Y, social function and long-term outcome in schizophrenia.

Stålberg G, Ekselius L, Lindström LH, Larhammar D, Bodén R.

Schizophr Res. 2014 Jul;156(2-3):223-7. doi: 10.1016/j.schres.2014.04.006. Epub 2014 May 3.

PMID:
24799298
23.

Molecular evolution of GPCRs: Somatostatin/urotensin II receptors.

Tostivint H, Ocampo Daza D, Bergqvist CA, Quan FB, Bougerol M, Lihrmann I, Larhammar D.

J Mol Endocrinol. 2014 Jun;52(3):T61-86. doi: 10.1530/JME-13-0274. Epub 2014 Apr 16. Review.

PMID:
24740737
24.

Detecting ligand interactions with G protein-coupled receptors in real-time on living cells.

Xu B, Varasteh Z, Orlova A, Andersson K, Larhammar D, Björkelund H.

Biochem Biophys Res Commun. 2013 Nov 29;441(4):820-4. doi: 10.1016/j.bbrc.2013.10.149. Epub 2013 Nov 6.

PMID:
24211197
26.

Mutagenesis and computational modeling of human G-protein-coupled receptor Y2 for neuropeptide Y and peptide YY.

Xu B, Fällmar H, Boukharta L, Pruner J, Lundell I, Mohell N, Gutiérrez-de-Terán H, Aqvist J, Larhammar D.

Biochemistry. 2013 Nov 12;52(45):7987-98. doi: 10.1021/bi400830c. Epub 2013 Oct 31.

PMID:
24111902
27.

Interactions of zebrafish peptide YYb with the neuropeptide Y-family receptors Y4, Y7, Y8a, and Y8b.

Sundström G, Larsson TA, Xu B, Heldin J, Larhammar D.

Front Neurosci. 2013 Mar 15;7:29. doi: 10.3389/fnins.2013.00029. eCollection 2013.

28.

Ancient Grandeur of the Vertebrate Neuropeptide Y System Shown by the Coelacanth Latimeria chalumnae.

Larhammar D, Bergqvist CA.

Front Neurosci. 2013 Mar 8;7:27. doi: 10.3389/fnins.2013.00027. eCollection 2013.

29.

The evolution of vertebrate somatostatin receptors and their gene regions involves extensive chromosomal rearrangements.

Ocampo Daza D, Sundström G, Bergqvist CA, Larhammar D.

BMC Evol Biol. 2012 Nov 29;12:231. doi: 10.1186/1471-2148-12-231.

30.

Cloning and pharmacological characterization of the neuropeptide Y receptor Y5 in the sea lamprey, Petromyzon marinus.

Xu B, Sundström G, Kuraku S, Lundell I, Larhammar D.

Peptides. 2013 Jan;39:64-70. doi: 10.1016/j.peptides.2012.11.007. Epub 2012 Nov 23.

PMID:
23178200
31.

Evolution of the vertebrate paralemmin gene family: ancient origin of gene duplicates suggests distinct functions.

Hultqvist G, Ocampo Daza D, Larhammar D, Kilimann MW.

PLoS One. 2012;7(7):e41850. doi: 10.1371/journal.pone.0041850. Epub 2012 Jul 25.

32.

Expansion of transducin subunit gene families in early vertebrate tetraploidizations.

Lagman D, Sundström G, Ocampo Daza D, Abalo XM, Larhammar D.

Genomics. 2012 Oct;100(4):203-11. doi: 10.1016/j.ygeno.2012.07.005. Epub 2012 Jul 17.

33.

Characterization of the neuropeptide Y system in the frog Silurana tropicalis (Pipidae): three peptides and six receptor subtypes.

Sundström G, Xu B, Larsson TA, Heldin J, Bergqvist CA, Fredriksson R, Conlon JM, Lundell I, Denver RJ, Larhammar D.

Gen Comp Endocrinol. 2012 Jul 1;177(3):322-31. doi: 10.1016/j.ygcen.2012.04.027. Epub 2012 May 4. Erratum in: Gen Comp Endocrinol. 2015 May 1;215:132-3.

PMID:
22565163
34.

The oxytocin/vasopressin receptor family has at least five members in the gnathostome lineage, inclucing two distinct V2 subtypes.

Ocampo Daza D, Lewicka M, Larhammar D.

Gen Comp Endocrinol. 2012 Jan 1;175(1):135-43. doi: 10.1016/j.ygcen.2011.10.011. Epub 2011 Oct 28.

PMID:
22057000
35.

Regulation of synaptic vesicle budding and dynamin function by an EHD ATPase.

Jakobsson J, Ackermann F, Andersson F, Larhammar D, Löw P, Brodin L.

J Neurosci. 2011 Sep 28;31(39):13972-80. doi: 10.1523/JNEUROSCI.1289-11.2011.

36.

Neuropeptide Y/peptide YY receptor Y2 duplicate in zebrafish with unique introns displays distinct peptide binding properties.

Fällmar H, Sundström G, Lundell I, Mohell N, Larhammar D.

Comp Biochem Physiol B Biochem Mol Biol. 2011 Dec;160(4):166-73. doi: 10.1016/j.cbpb.2011.08.001. Epub 2011 Aug 10.

PMID:
21855645
37.

Identification of positions in the human neuropeptide Y/peptide YY receptor Y2 that contribute to pharmacological differences between receptor subtypes.

Fällmar H, Åkerberg H, Gutiérrez-de-Terán H, Lundell I, Mohell N, Larhammar D.

Neuropeptides. 2011 Aug;45(4):293-300. doi: 10.1016/j.npep.2011.05.006. Epub 2011 Jun 22.

PMID:
21696823
38.

Evolution of the insulin-like growth factor binding protein (IGFBP) family.

Daza DO, Sundström G, Bergqvist CA, Duan C, Larhammar D.

Endocrinology. 2011 Jun;152(6):2278-89. doi: 10.1210/en.2011-0047. Epub 2011 Apr 19.

PMID:
21505050
39.

Internalization studies of chimeric neuropeptide Y receptors Y1 and Y2 suggest complex interactions between cytoplasmic domains.

Lundell I, Rabe Bernhardt N, Johnsson AK, Larhammar D.

Regul Pept. 2011 Jun 7;168(1-3):50-8. doi: 10.1016/j.regpep.2011.03.004. Epub 2011 Apr 12.

PMID:
21466826
40.

Differential evolution of voltage-gated sodium channels in tetrapods and teleost fishes.

Widmark J, Sundström G, Ocampo Daza D, Larhammar D.

Mol Biol Evol. 2011 Jan;28(1):859-71. doi: 10.1093/molbev/msq257. Epub 2010 Oct 5.

PMID:
20924084
41.

Mutagenesis of human neuropeptide Y/peptide YY receptor Y2 reveals additional differences to Y1 in interactions with highly conserved ligand positions.

Akerberg H, Fällmar H, Sjödin P, Boukharta L, Gutiérrez-de-Terán H, Lundell I, Mohell N, Larhammar D.

Regul Pept. 2010 Aug 9;163(1-3):120-9. doi: 10.1016/j.regpep.2010.04.011. Epub 2010 May 13.

PMID:
20471432
42.

Concomitant duplications of opioid peptide and receptor genes before the origin of jawed vertebrates.

Sundström G, Dreborg S, Larhammar D.

PLoS One. 2010 May 6;5(5):e10512. doi: 10.1371/journal.pone.0010512.

43.

Peripheral administration of pancreatic polypeptide inhibits components of food-intake behavior in dogs.

Akerberg H, Meyerson B, Sallander M, Lagerstedt AS, Hedhammar A, Larhammar D.

Peptides. 2010 Jun;31(6):1055-61. doi: 10.1016/j.peptides.2010.03.019. Epub 2010 Mar 23.

PMID:
20338207
44.

Evolution of vertebrate rod and cone phototransduction genes.

Larhammar D, Nordström K, Larsson TA.

Philos Trans R Soc Lond B Biol Sci. 2009 Oct 12;364(1531):2867-80. doi: 10.1098/rstb.2009.0077. Review.

45.

Perspective on Roseroot (Rhodiola rosea) studies.

Blomkvist J, Taube A, Larhammar D.

Planta Med. 2009 Sep;75(11):1187-90. doi: 10.1055/s-0029-1185720. Epub 2009 May 25. Review.

PMID:
19468971
46.

Evolution of the growth hormone-prolactin-somatolactin system in relation to vertebrate tetraploidizations.

Ocampo Daza D, Sundström G, Larsson TA, Larhammar D.

Ann N Y Acad Sci. 2009 Apr;1163:491-3. doi: 10.1111/j.1749-6632.2008.03671.x.

PMID:
19456396
47.

Early duplications of opioid receptor and Peptide genes in vertebrate evolution.

Larhammar D, Dreborg S, Larsson TA, Sundström G.

Ann N Y Acad Sci. 2009 Apr;1163:451-3. doi: 10.1111/j.1749-6632.2008.03672.x.

PMID:
19456384
48.

Major genomic events and their consequences for vertebrate evolution and endocrinology.

Larhammar D, Sundström G, Dreborg S, Daza DO, Larsson TA.

Ann N Y Acad Sci. 2009 Apr;1163:201-8. doi: 10.1111/j.1749-6632.2008.03659.x. Review.

PMID:
19456340
49.

Steroid biosynthesis within the frog brain: a model of neuroendocrine regulation.

Do Rego JL, Seong JY, Burel D, Luu-The V, Larhammar D, Tsutsui K, Pelletier G, Tonon MC, Vaudry H.

Ann N Y Acad Sci. 2009 Apr;1163:83-92. doi: 10.1111/j.1749-6632.2008.03664.x. Review.

PMID:
19456330
50.

Neuropeptide Y and gamma-melanocyte stimulating hormone (gamma-MSH) share a common pressor mechanism of action.

Gruber KA, Fan W, Akerberg H, Larhammar D, Chee MJ, Colmers WF, Cone RD.

Endocrine. 2009 Jun;35(3):312-24. doi: 10.1007/s12020-008-9141-3. Epub 2009 Apr 11.

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