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Items: 1 to 50 of 224

1.

Circadian regulation of phosphodiesterase 6 genes in zebrafish differs between cones and rods: Implications for photopic and scotopic vision.

Abalo XM, Lagman D, Heras G, Del Pozo A, Eggert J, Larhammar D.

Vision Res. 2020 Jan;166:43-51. doi: 10.1016/j.visres.2019.11.001. Epub 2019 Dec 16.

PMID:
31855667
2.

The Neuropeptide Y Y2 Receptor Is Coexpressed with Nppb in Primary Afferent Neurons and Y2 Activation Reduces Histaminergic and IL-31-Induced Itch.

Ma H, Gao T, Jakobsson JET, Weman HM, Xu B, Larhammar D, Lagerström MC.

J Pharmacol Exp Ther. 2020 Jan;372(1):73-82. doi: 10.1124/jpet.119.262584. Epub 2019 Nov 26.

PMID:
31771994
3.

Editorial: Endocrine and Neuroendocrine Systems of Invertebrate Deuterostomes.

Satake H, Larhammar D, Elphick MR.

Front Endocrinol (Lausanne). 2019 Nov 1;10:755. doi: 10.3389/fendo.2019.00755. eCollection 2019. No abstract available.

4.

Globalization of Traditional Chinese Medicine: what are the issues for ensuring evidence-based diagnosis and therapy?

Fears R, Griffin GE, Larhammar D, Ter Meulen V, van der Meer JWM.

J Intern Med. 2020 Feb;287(2):210-213. doi: 10.1111/joim.12989. Epub 2019 Nov 7. No abstract available.

PMID:
31697414
5.

Functional characterization in vitro of twelve naturally occurring variants of the human pancreatic polypeptide receptor NPY4R.

Shebanits K, Vasile S, Xu B, Gutiérrez-de-Terán H, Larhammar D.

Neuropeptides. 2019 Aug;76:101933. doi: 10.1016/j.npep.2019.05.004. Epub 2019 May 15.

6.

Copy number determination of the gene for the human pancreatic polypeptide receptor NPY4R using read depth analysis and droplet digital PCR.

Shebanits K, Günther T, Johansson ACV, Maqbool K, Feuk L, Jakobsson M, Larhammar D.

BMC Biotechnol. 2019 Jun 4;19(1):31. doi: 10.1186/s12896-019-0523-9.

7.

Evolution of vertebrate nicotinic acetylcholine receptors.

Pedersen JE, Bergqvist CA, Larhammar D.

BMC Evol Biol. 2019 Jan 30;19(1):38. doi: 10.1186/s12862-018-1341-8.

8.

Evolution of the Muscarinic Acetylcholine Receptors in Vertebrates.

Pedersen JE, Bergqvist CA, Larhammar D.

eNeuro. 2018 Nov 8;5(5). pii: ENEURO.0340-18.2018. doi: 10.1523/ENEURO.0340-18.2018. eCollection 2018 Sep-Oct.

9.

Correction: Evolution of neuropeptide signalling systems (doi:10.1242/jeb.151092).

Elphick MR, Mirabeau O, Larhammar D.

J Exp Biol. 2018 Oct 10;221(Pt 19). pii: jeb193342. doi: 10.1242/jeb.193342. No abstract available.

10.

The Neuropeptide Y System Regulates Both Mechanical and Histaminergic Itch.

Gao T, Ma H, Xu B, Bergman J, Larhammar D, Lagerström MC.

J Invest Dermatol. 2018 Nov;138(11):2405-2411. doi: 10.1016/j.jid.2018.05.008. Epub 2018 May 24.

11.

Structural basis of ligand binding modes at the neuropeptide Y Y1 receptor.

Yang Z, Han S, Keller M, Kaiser A, Bender BJ, Bosse M, Burkert K, Kögler LM, Wifling D, Bernhardt G, Plank N, Littmann T, Schmidt P, Yi C, Li B, Ye S, Zhang R, Xu B, Larhammar D, Stevens RC, Huster D, Meiler J, Zhao Q, Beck-Sickinger AG, Buschauer A, Wu B.

Nature. 2018 Apr;556(7702):520-524. doi: 10.1038/s41586-018-0046-x. Epub 2018 Apr 18.

12.

Copy number of pancreatic polypeptide receptor gene NPY4R correlates with body mass index and waist circumference.

Shebanits K, Andersson-Assarsson JC, Larsson I, Carlsson LMS, Feuk L, Larhammar D.

PLoS One. 2018 Apr 5;13(4):e0194668. doi: 10.1371/journal.pone.0194668. eCollection 2018.

13.

Evolution of neuropeptide signalling systems.

Elphick MR, Mirabeau O, Larhammar D.

J Exp Biol. 2018 Feb 9;221(Pt 3). pii: jeb151092. doi: 10.1242/jeb.151092. Review. Erratum in: J Exp Biol. 2018 Oct 10;221(Pt 19):.

14.

Elucidation of the Binding Mode of the Carboxyterminal Region of Peptide YY to the Human Y2 Receptor.

Xu B, Vasile S, Østergaard S, Paulsson JF, Pruner J, Åqvist J, Wulff BS, Gutiérrez-de-Terán H, Larhammar D.

Mol Pharmacol. 2018 Apr;93(4):323-334. doi: 10.1124/mol.117.110627. Epub 2018 Jan 24.

PMID:
29367257
15.

Evolution of the growth hormone, prolactin, prolactin 2 and somatolactin family.

Ocampo Daza D, Larhammar D.

Gen Comp Endocrinol. 2018 Aug 1;264:94-112. doi: 10.1016/j.ygcen.2018.01.007. Epub 2018 Jan 12.

PMID:
29339183
16.

Assessing and regulating homeopathic products.

Fears R, Griffin G, Larhammar D, Ter Meulen V, van der Meer JWM.

J Intern Med. 2017 Dec;282(6):563-565. doi: 10.1111/joim.12676. Epub 2017 Sep 25. No abstract available.

17.

Evolution of the receptors for growth hormone, prolactin, erythropoietin and thrombopoietin in relation to the vertebrate tetraploidizations.

Ocampo Daza D, Larhammar D.

Gen Comp Endocrinol. 2018 Feb 1;257:143-160. doi: 10.1016/j.ygcen.2017.06.021. Epub 2017 Jun 23.

PMID:
28652136
18.

The Arg-Phe-amide peptide 26RFa/glutamine RF-amide peptide and its receptor: IUPHAR Review 24.

Leprince J, Bagnol D, Bureau R, Fukusumi S, Granata R, Hinuma S, Larhammar D, Primeaux S, Sopkova-de Oliveiras Santos J, Tsutsui K, Ukena K, Vaudry H.

Br J Pharmacol. 2017 Oct;174(20):3573-3607. doi: 10.1111/bph.13907. Epub 2017 Sep 8. Review.

19.

Evolution and expression of the phosphodiesterase 6 genes unveils vertebrate novelty to control photosensitivity.

Lagman D, Franzén IE, Eggert J, Larhammar D, Abalo XM.

BMC Evol Biol. 2016 Jun 13;16(1):124. doi: 10.1186/s12862-016-0695-z.

20.

Corticotropin-releasing hormone family evolution: five ancestral genes remain in some lineages.

Cardoso JC, Bergqvist CA, Félix RC, Larhammar D.

J Mol Endocrinol. 2016 Jul;57(1):73-86. doi: 10.1530/JME-16-0051. Epub 2016 May 24.

PMID:
27220618
21.

Neuropeptide Y family receptors Y1 and Y2 from sea lamprey, Petromyzon marinus.

Xu B, Lagman D, Sundström G, Larhammar D.

Gen Comp Endocrinol. 2015 Oct 1;222:106-15. doi: 10.1016/j.ygcen.2015.08.005. Epub 2015 Aug 6.

PMID:
26255155
22.

Transducin duplicates in the zebrafish retina and pineal complex: differential specialisation after the teleost tetraploidisation.

Lagman D, Callado-Pérez A, Franzén IE, Larhammar D, Abalo XM.

PLoS One. 2015 Mar 25;10(3):e0121330. doi: 10.1371/journal.pone.0121330. eCollection 2015.

23.

Ancestral vertebrate complexity of the opioid system.

Larhammar D, Bergqvist C, Sundström G.

Vitam Horm. 2015;97:95-122. doi: 10.1016/bs.vh.2014.11.001. Epub 2015 Jan 23. Review.

PMID:
25677769
24.

Characterization of peptide QRFP (26RFa) and its receptor from amphioxus, Branchiostoma floridae.

Xu B, Bergqvist CA, Sundström G, Lundell I, Vaudry H, Leprince J, Larhammar D.

Gen Comp Endocrinol. 2015 Jan 1;210:107-13. doi: 10.1016/j.ygcen.2014.10.010. Epub 2014 Oct 25.

PMID:
25449662
25.

Unexpected multiplicity of QRFP receptors in early vertebrate evolution.

Larhammar D, Xu B, Bergqvist CA.

Front Neurosci. 2014 Oct 24;8:337. doi: 10.3389/fnins.2014.00337. eCollection 2014.

26.

Comparative evolution of peptide hormone-binding GPCRs: a route to understanding functional complexity.

Cardoso JC, Larhammar D.

Gen Comp Endocrinol. 2014 Dec 1;209:1-2. doi: 10.1016/j.ygcen.2014.10.001. Epub 2014 Oct 7. No abstract available.

PMID:
25304823
27.

New insights into the evolution of vertebrate CRH (corticotropin-releasing hormone) and invertebrate DH44 (diuretic hormone 44) receptors in metazoans.

Cardoso JC, Félix RC, Bergqvist CA, Larhammar D.

Gen Comp Endocrinol. 2014 Dec 1;209:162-70. doi: 10.1016/j.ygcen.2014.09.004. Epub 2014 Sep 16. Review.

PMID:
25230393
28.

Turtle ghrelin.

Larhammar D, Lagman D.

Nat Genet. 2014 Jun;46(6):524-5. doi: 10.1038/ng.2960. No abstract available.

PMID:
24866184
29.

Neuropeptide Y, social function and long-term outcome in schizophrenia.

Stålberg G, Ekselius L, Lindström LH, Larhammar D, Bodén R.

Schizophr Res. 2014 Jul;156(2-3):223-7. doi: 10.1016/j.schres.2014.04.006. Epub 2014 May 3.

PMID:
24799298
30.

Molecular evolution of GPCRs: Somatostatin/urotensin II receptors.

Tostivint H, Ocampo Daza D, Bergqvist CA, Quan FB, Bougerol M, Lihrmann I, Larhammar D.

J Mol Endocrinol. 2014 Jun;52(3):T61-86. doi: 10.1530/JME-13-0274. Epub 2014 Apr 16. Review.

PMID:
24740737
31.

Detecting ligand interactions with G protein-coupled receptors in real-time on living cells.

Xu B, Varasteh Z, Orlova A, Andersson K, Larhammar D, Björkelund H.

Biochem Biophys Res Commun. 2013 Nov 29;441(4):820-4. doi: 10.1016/j.bbrc.2013.10.149. Epub 2013 Nov 6.

PMID:
24211197
33.

Mutagenesis and computational modeling of human G-protein-coupled receptor Y2 for neuropeptide Y and peptide YY.

Xu B, Fällmar H, Boukharta L, Pruner J, Lundell I, Mohell N, Gutiérrez-de-Terán H, Aqvist J, Larhammar D.

Biochemistry. 2013 Nov 12;52(45):7987-98. doi: 10.1021/bi400830c. Epub 2013 Oct 31.

PMID:
24111902
34.

Interactions of zebrafish peptide YYb with the neuropeptide Y-family receptors Y4, Y7, Y8a, and Y8b.

Sundström G, Larsson TA, Xu B, Heldin J, Larhammar D.

Front Neurosci. 2013 Mar 15;7:29. doi: 10.3389/fnins.2013.00029. eCollection 2013.

35.

Ancient Grandeur of the Vertebrate Neuropeptide Y System Shown by the Coelacanth Latimeria chalumnae.

Larhammar D, Bergqvist CA.

Front Neurosci. 2013 Mar 8;7:27. doi: 10.3389/fnins.2013.00027. eCollection 2013.

36.

The evolution of vertebrate somatostatin receptors and their gene regions involves extensive chromosomal rearrangements.

Ocampo Daza D, Sundström G, Bergqvist CA, Larhammar D.

BMC Evol Biol. 2012 Nov 29;12:231. doi: 10.1186/1471-2148-12-231.

37.

Cloning and pharmacological characterization of the neuropeptide Y receptor Y5 in the sea lamprey, Petromyzon marinus.

Xu B, Sundström G, Kuraku S, Lundell I, Larhammar D.

Peptides. 2013 Jan;39:64-70. doi: 10.1016/j.peptides.2012.11.007. Epub 2012 Nov 23.

PMID:
23178200
38.

Evolution of the vertebrate paralemmin gene family: ancient origin of gene duplicates suggests distinct functions.

Hultqvist G, Ocampo Daza D, Larhammar D, Kilimann MW.

PLoS One. 2012;7(7):e41850. doi: 10.1371/journal.pone.0041850. Epub 2012 Jul 25.

39.

Expansion of transducin subunit gene families in early vertebrate tetraploidizations.

Lagman D, Sundström G, Ocampo Daza D, Abalo XM, Larhammar D.

Genomics. 2012 Oct;100(4):203-11. doi: 10.1016/j.ygeno.2012.07.005. Epub 2012 Jul 17.

40.

Characterization of the neuropeptide Y system in the frog Silurana tropicalis (Pipidae): three peptides and six receptor subtypes.

Sundström G, Xu B, Larsson TA, Heldin J, Bergqvist CA, Fredriksson R, Conlon JM, Lundell I, Denver RJ, Larhammar D.

Gen Comp Endocrinol. 2012 Jul 1;177(3):322-31. doi: 10.1016/j.ygcen.2012.04.027. Epub 2012 May 4. Erratum in: Gen Comp Endocrinol. 2015 May 1;215:132-3.

PMID:
22565163
41.

The oxytocin/vasopressin receptor family has at least five members in the gnathostome lineage, inclucing two distinct V2 subtypes.

Ocampo Daza D, Lewicka M, Larhammar D.

Gen Comp Endocrinol. 2012 Jan 1;175(1):135-43. doi: 10.1016/j.ygcen.2011.10.011. Epub 2011 Oct 28.

PMID:
22057000
42.

Regulation of synaptic vesicle budding and dynamin function by an EHD ATPase.

Jakobsson J, Ackermann F, Andersson F, Larhammar D, Löw P, Brodin L.

J Neurosci. 2011 Sep 28;31(39):13972-80. doi: 10.1523/JNEUROSCI.1289-11.2011.

43.

Neuropeptide Y/peptide YY receptor Y2 duplicate in zebrafish with unique introns displays distinct peptide binding properties.

Fällmar H, Sundström G, Lundell I, Mohell N, Larhammar D.

Comp Biochem Physiol B Biochem Mol Biol. 2011 Dec;160(4):166-73. doi: 10.1016/j.cbpb.2011.08.001. Epub 2011 Aug 10.

PMID:
21855645
44.

Identification of positions in the human neuropeptide Y/peptide YY receptor Y2 that contribute to pharmacological differences between receptor subtypes.

Fällmar H, Åkerberg H, Gutiérrez-de-Terán H, Lundell I, Mohell N, Larhammar D.

Neuropeptides. 2011 Aug;45(4):293-300. doi: 10.1016/j.npep.2011.05.006. Epub 2011 Jun 22.

PMID:
21696823
45.

Evolution of the insulin-like growth factor binding protein (IGFBP) family.

Daza DO, Sundström G, Bergqvist CA, Duan C, Larhammar D.

Endocrinology. 2011 Jun;152(6):2278-89. doi: 10.1210/en.2011-0047. Epub 2011 Apr 19.

PMID:
21505050
46.

Internalization studies of chimeric neuropeptide Y receptors Y1 and Y2 suggest complex interactions between cytoplasmic domains.

Lundell I, Rabe Bernhardt N, Johnsson AK, Larhammar D.

Regul Pept. 2011 Jun 7;168(1-3):50-8. doi: 10.1016/j.regpep.2011.03.004. Epub 2011 Apr 12.

PMID:
21466826
47.

Differential evolution of voltage-gated sodium channels in tetrapods and teleost fishes.

Widmark J, Sundström G, Ocampo Daza D, Larhammar D.

Mol Biol Evol. 2011 Jan;28(1):859-71. doi: 10.1093/molbev/msq257. Epub 2010 Oct 5.

PMID:
20924084
48.

Mutagenesis of human neuropeptide Y/peptide YY receptor Y2 reveals additional differences to Y1 in interactions with highly conserved ligand positions.

Akerberg H, Fällmar H, Sjödin P, Boukharta L, Gutiérrez-de-Terán H, Lundell I, Mohell N, Larhammar D.

Regul Pept. 2010 Aug 9;163(1-3):120-9. doi: 10.1016/j.regpep.2010.04.011. Epub 2010 May 13.

PMID:
20471432
49.

Concomitant duplications of opioid peptide and receptor genes before the origin of jawed vertebrates.

Sundström G, Dreborg S, Larhammar D.

PLoS One. 2010 May 6;5(5):e10512. doi: 10.1371/journal.pone.0010512.

50.

Peripheral administration of pancreatic polypeptide inhibits components of food-intake behavior in dogs.

Akerberg H, Meyerson B, Sallander M, Lagerstedt AS, Hedhammar A, Larhammar D.

Peptides. 2010 Jun;31(6):1055-61. doi: 10.1016/j.peptides.2010.03.019. Epub 2010 Mar 23.

PMID:
20338207

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