Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 27

1.

CRISPR DNA base editors with reduced RNA off-target and self-editing activities.

Grünewald J, Zhou R, Iyer S, Lareau CA, Garcia SP, Aryee MJ, Joung JK.

Nat Biotechnol. 2019 Sep;37(9):1041-1048. doi: 10.1038/s41587-019-0236-6. Epub 2019 Sep 2.

PMID:
31477922
2.

Droplet-based combinatorial indexing for massive-scale single-cell chromatin accessibility.

Lareau CA, Duarte FM, Chew JG, Kartha VK, Burkett ZD, Kohlway AS, Pokholok D, Aryee MJ, Steemers FJ, Lebofsky R, Buenrostro JD.

Nat Biotechnol. 2019 Aug;37(8):916-924. doi: 10.1038/s41587-019-0147-6. Epub 2019 Jun 24.

PMID:
31235917
3.

Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis.

Ludwig LS, Lareau CA, Bao EL, Nandakumar SK, Muus C, Ulirsch JC, Chowdhary K, Buenrostro JD, Mohandas N, An X, Aryee MJ, Regev A, Sankaran VG.

Cell Rep. 2019 Jun 11;27(11):3228-3240.e7. doi: 10.1016/j.celrep.2019.05.046.

4.

Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis.

Nandakumar SK, McFarland SK, Mateyka LM, Lareau CA, Ulirsch JC, Ludwig LS, Agarwal G, Engreitz JM, Przychodzen B, McConkey M, Cowley GS, Doench JG, Maciejewski JP, Ebert BL, Root DE, Sankaran VG.

Elife. 2019 May 9;8. pii: e44080. doi: 10.7554/eLife.44080.

5.

Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM.

Chen H, Albergante L, Hsu JY, Lareau CA, Lo Bosco G, Guan J, Zhou S, Gorban AN, Bauer DE, Aryee MJ, Langenau DM, Zinovyev A, Buenrostro JD, Yuan GC, Pinello L.

Nat Commun. 2019 Apr 23;10(1):1903. doi: 10.1038/s41467-019-09670-4.

6.

Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors.

Grünewald J, Zhou R, Garcia SP, Iyer S, Lareau CA, Aryee MJ, Joung JK.

Nature. 2019 May;569(7756):433-437. doi: 10.1038/s41586-019-1161-z. Epub 2019 Apr 17.

PMID:
30995674
7.

Impaired human hematopoiesis due to a cryptic intronic GATA1 splicing mutation.

Abdulhay NJ, Fiorini C, Verboon JM, Ludwig LS, Ulirsch JC, Zieger B, Lareau CA, Mi X, Roy A, Obeng EA, Erlacher M, Gupta N, Gabriel SB, Ebert BL, Niemeyer CM, Khoriaty RN, Ancliff P, Gazda HT, Wlodarski MW, Sankaran VG.

J Exp Med. 2019 May 6;216(5):1050-1060. doi: 10.1084/jem.20181625. Epub 2019 Mar 26.

PMID:
30914438
8.

The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting.

Pan J, McKenzie ZM, D'Avino AR, Mashtalir N, Lareau CA, St Pierre R, Wang L, Shilatifard A, Kadoch C.

Nat Genet. 2019 Apr;51(4):618-626. doi: 10.1038/s41588-019-0363-5. Epub 2019 Mar 11.

PMID:
30858614
9.

Interrogation of human hematopoiesis at single-cell and single-variant resolution.

Ulirsch JC, Lareau CA, Bao EL, Ludwig LS, Guo MH, Benner C, Satpathy AT, Kartha VK, Salem RM, Hirschhorn JN, Finucane HK, Aryee MJ, Buenrostro JD, Sankaran VG.

Nat Genet. 2019 Apr;51(4):683-693. doi: 10.1038/s41588-019-0362-6. Epub 2019 Mar 11.

10.

Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics.

Ludwig LS, Lareau CA, Ulirsch JC, Christian E, Muus C, Li LH, Pelka K, Ge W, Oren Y, Brack A, Law T, Rodman C, Chen JH, Boland GM, Hacohen N, Rozenblatt-Rosen O, Aryee MJ, Buenrostro JD, Regev A, Sankaran VG.

Cell. 2019 Mar 7;176(6):1325-1339.e22. doi: 10.1016/j.cell.2019.01.022. Epub 2019 Feb 28.

PMID:
30827679
11.

The cis-Regulatory Atlas of the Mouse Immune System.

Yoshida H, Lareau CA, Ramirez RN, Rose SA, Maier B, Wroblewska A, Desland F, Chudnovskiy A, Mortha A, Dominguez C, Tellier J, Kim E, Dwyer D, Shinton S, Nabekura T, Qi Y, Yu B, Robinette M, Kim KW, Wagers A, Rhoads A, Nutt SL, Brown BD, Mostafavi S, Buenrostro JD, Benoist C; Immunological Genome Project.

Cell. 2019 Feb 7;176(4):897-912.e20. doi: 10.1016/j.cell.2018.12.036. Epub 2019 Jan 24.

PMID:
30686579
12.

Heritability of fetal hemoglobin, white cell count, and other clinical traits from a sickle cell disease family cohort.

Bao EL, Lareau CA, Brugnara C, Fulcher IR, Barau C, Moutereau S, Habibi A, Badaoui B, Berkenou J, Bartolucci P, Galactéros F, Platt OS, Mahaney M, Sankaran VG.

Am J Hematol. 2019 May;94(5):522-527. doi: 10.1002/ajh.25421. Epub 2019 Feb 6.

PMID:
30680775
13.

A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation.

Michel BC, D'Avino AR, Cassel SH, Mashtalir N, McKenzie ZM, McBride MJ, Valencia AM, Zhou Q, Bocker M, Soares LMM, Pan J, Remillard DI, Lareau CA, Zullow HJ, Fortoul N, Gray NS, Bradner JE, Chan HM, Kadoch C.

Nat Cell Biol. 2018 Dec;20(12):1410-1420. doi: 10.1038/s41556-018-0221-1. Epub 2018 Nov 5.

14.

Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks.

Pelikan RC, Kelly JA, Fu Y, Lareau CA, Tessneer KL, Wiley GB, Wiley MM, Glenn SB, Harley JB, Guthridge JM, James JA, Aryee MJ, Montgomery C, Gaffney PM.

Nat Commun. 2018 Jul 25;9(1):2905. doi: 10.1038/s41467-018-05328-9.

15.

Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation.

Buenrostro JD, Corces MR, Lareau CA, Wu B, Schep AN, Aryee MJ, Majeti R, Chang HY, Greenleaf WJ.

Cell. 2018 May 31;173(6):1535-1548.e16. doi: 10.1016/j.cell.2018.03.074. Epub 2018 Apr 26.

16.

Transcript-indexed ATAC-seq for precision immune profiling.

Satpathy AT, Saligrama N, Buenrostro JD, Wei Y, Wu B, Rubin AJ, Granja JM, Lareau CA, Li R, Qi Y, Parker KR, Mumbach MR, Serratelli WS, Gennert DG, Schep AN, Corces MR, Khodadoust MS, Kim YH, Khavari PA, Greenleaf WJ, Davis MM, Chang HY.

Nat Med. 2018 May;24(5):580-590. doi: 10.1038/s41591-018-0008-8. Epub 2018 Apr 23.

17.

Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo".

Lareau CA, Clement K, Hsu JY, Pattanayak V, Joung JK, Aryee MJ, Pinello L.

Nat Methods. 2018 Apr;15(4):238-239. doi: 10.1038/nmeth.4541. Epub 2018 Mar 30. No abstract available.

PMID:
29600992
18.

hichipper: a preprocessing pipeline for calling DNA loops from HiChIP data.

Lareau CA, Aryee MJ.

Nat Methods. 2018 Feb 28;15(3):155-156. doi: 10.1038/nmeth.4583. No abstract available.

PMID:
29489746
19.

A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas.

Ryan RJH, Petrovic J, Rausch DM, Zhou Y, Lareau CA, Kluk MJ, Christie AL, Lee WY, Tarjan DR, Guo B, Donohue LKH, Gillespie SM, Nardi V, Hochberg EP, Blacklow SC, Weinstock DM, Faryabi RB, Bernstein BE, Aster JC, Pear WS.

Cell Rep. 2017 Oct 17;21(3):784-797. doi: 10.1016/j.celrep.2017.09.066.

20.

diffloop: a computational framework for identifying and analyzing differential DNA loops from sequencing data.

Lareau CA, Aryee MJ.

Bioinformatics. 2018 Feb 15;34(4):672-674. doi: 10.1093/bioinformatics/btx623.

21.

Polygenic risk assessment reveals pleiotropy between sarcoidosis and inflammatory disorders in the context of genetic ancestry.

Lareau CA, DeWeese CF, Adrianto I, Lessard CJ, Gaffney PM, Iannuzzi MC, Rybicki BA, Levin AM, Montgomery CG.

Genes Immun. 2017 Mar;18(2):88-94. doi: 10.1038/gene.2017.3. Epub 2017 Mar 9.

22.

An interaction quantitative trait loci tool implicates epistatic functional variants in an apoptosis pathway in smallpox vaccine eQTL data.

Lareau CA, White BC, Oberg AL, Kennedy RB, Poland GA, McKinney BA.

Genes Immun. 2016 Jun;17(4):244-50. doi: 10.1038/gene.2016.15. Epub 2016 Apr 7.

PMID:
27052692
23.

dcVar: a method for identifying common variants that modulate differential correlation structures in gene expression data.

Lareau CA, White BC, Montgomery CG, McKinney BA.

Front Genet. 2015 Oct 19;6:312. doi: 10.3389/fgene.2015.00312. eCollection 2015.

24.

Fine mapping of chromosome 15q25 implicates ZNF592 in neurosarcoidosis patients.

Lareau CA, Adrianto I, Levin AM, Iannuzzi MC, Rybicki BA, Montgomery CG.

Ann Clin Transl Neurol. 2015 Oct;2(10):972-7. doi: 10.1002/acn3.229. Epub 2015 Jul 31.

25.

Differential co-expression network centrality and machine learning feature selection for identifying susceptibility hubs in networks with scale-free structure.

Lareau CA, White BC, Oberg AL, McKinney BA.

BioData Min. 2015 Feb 3;8:5. doi: 10.1186/s13040-015-0040-x. eCollection 2015.

26.

Network theory for data-driven epistasis networks.

Lareau CA, McKinney BA.

Methods Mol Biol. 2015;1253:285-300. doi: 10.1007/978-1-4939-2155-3_15.

PMID:
25403538
27.

Encore: Genetic Association Interaction Network centrality pipeline and application to SLE exome data.

Davis NA, Lareau CA, White BC, Pandey A, Wiley G, Montgomery CG, Gaffney PM, McKinney BA.

Genet Epidemiol. 2013 Sep;37(6):614-21. doi: 10.1002/gepi.21739. Epub 2013 Jun 5.

Supplemental Content

Loading ...
Support Center