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Items: 15


A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation.

Michel BC, D'Avino AR, Cassel SH, Mashtalir N, McKenzie ZM, McBride MJ, Valencia AM, Zhou Q, Bocker M, Soares LMM, Pan J, Remillard DI, Lareau CA, Zullow HJ, Fortoul N, Gray NS, Bradner JE, Chan HM, Kadoch C.

Nat Cell Biol. 2018 Nov 5. doi: 10.1038/s41556-018-0221-1. [Epub ahead of print]


Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks.

Pelikan RC, Kelly JA, Fu Y, Lareau CA, Tessneer KL, Wiley GB, Wiley MM, Glenn SB, Harley JB, Guthridge JM, James JA, Aryee MJ, Montgomery C, Gaffney PM.

Nat Commun. 2018 Jul 25;9(1):2905. doi: 10.1038/s41467-018-05328-9.


Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation.

Buenrostro JD, Corces MR, Lareau CA, Wu B, Schep AN, Aryee MJ, Majeti R, Chang HY, Greenleaf WJ.

Cell. 2018 May 31;173(6):1535-1548.e16. doi: 10.1016/j.cell.2018.03.074. Epub 2018 Apr 26.


Transcript-indexed ATAC-seq for precision immune profiling.

Satpathy AT, Saligrama N, Buenrostro JD, Wei Y, Wu B, Rubin AJ, Granja JM, Lareau CA, Li R, Qi Y, Parker KR, Mumbach MR, Serratelli WS, Gennert DG, Schep AN, Corces MR, Khodadoust MS, Kim YH, Khavari PA, Greenleaf WJ, Davis MM, Chang HY.

Nat Med. 2018 May;24(5):580-590. doi: 10.1038/s41591-018-0008-8. Epub 2018 Apr 23.


Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo".

Lareau CA, Clement K, Hsu JY, Pattanayak V, Joung JK, Aryee MJ, Pinello L.

Nat Methods. 2018 Apr;15(4):238-239. doi: 10.1038/nmeth.4541. Epub 2018 Mar 30. No abstract available.


hichipper: a preprocessing pipeline for calling DNA loops from HiChIP data.

Lareau CA, Aryee MJ.

Nat Methods. 2018 Feb 28;15(3):155-156. doi: 10.1038/nmeth.4583. No abstract available.


A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas.

Ryan RJH, Petrovic J, Rausch DM, Zhou Y, Lareau CA, Kluk MJ, Christie AL, Lee WY, Tarjan DR, Guo B, Donohue LKH, Gillespie SM, Nardi V, Hochberg EP, Blacklow SC, Weinstock DM, Faryabi RB, Bernstein BE, Aster JC, Pear WS.

Cell Rep. 2017 Oct 17;21(3):784-797. doi: 10.1016/j.celrep.2017.09.066.


diffloop: a computational framework for identifying and analyzing differential DNA loops from sequencing data.

Lareau CA, Aryee MJ.

Bioinformatics. 2018 Feb 15;34(4):672-674. doi: 10.1093/bioinformatics/btx623.


Polygenic risk assessment reveals pleiotropy between sarcoidosis and inflammatory disorders in the context of genetic ancestry.

Lareau CA, DeWeese CF, Adrianto I, Lessard CJ, Gaffney PM, Iannuzzi MC, Rybicki BA, Levin AM, Montgomery CG.

Genes Immun. 2017 Mar;18(2):88-94. doi: 10.1038/gene.2017.3. Epub 2017 Mar 9.


An interaction quantitative trait loci tool implicates epistatic functional variants in an apoptosis pathway in smallpox vaccine eQTL data.

Lareau CA, White BC, Oberg AL, Kennedy RB, Poland GA, McKinney BA.

Genes Immun. 2016 Jun;17(4):244-50. doi: 10.1038/gene.2016.15. Epub 2016 Apr 7.


dcVar: a method for identifying common variants that modulate differential correlation structures in gene expression data.

Lareau CA, White BC, Montgomery CG, McKinney BA.

Front Genet. 2015 Oct 19;6:312. doi: 10.3389/fgene.2015.00312. eCollection 2015.


Fine mapping of chromosome 15q25 implicates ZNF592 in neurosarcoidosis patients.

Lareau CA, Adrianto I, Levin AM, Iannuzzi MC, Rybicki BA, Montgomery CG.

Ann Clin Transl Neurol. 2015 Oct;2(10):972-7. doi: 10.1002/acn3.229. Epub 2015 Jul 31.


Differential co-expression network centrality and machine learning feature selection for identifying susceptibility hubs in networks with scale-free structure.

Lareau CA, White BC, Oberg AL, McKinney BA.

BioData Min. 2015 Feb 3;8:5. doi: 10.1186/s13040-015-0040-x. eCollection 2015.


Network theory for data-driven epistasis networks.

Lareau CA, McKinney BA.

Methods Mol Biol. 2015;1253:285-300. doi: 10.1007/978-1-4939-2155-3_15.


Encore: Genetic Association Interaction Network centrality pipeline and application to SLE exome data.

Davis NA, Lareau CA, White BC, Pandey A, Wiley G, Montgomery CG, Gaffney PM, McKinney BA.

Genet Epidemiol. 2013 Sep;37(6):614-21. doi: 10.1002/gepi.21739. Epub 2013 Jun 5.

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