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Items: 1 to 50 of 60

1.

CRISPR DNA base editors with reduced RNA off-target and self-editing activities.

Grünewald J, Zhou R, Iyer S, Lareau CA, Garcia SP, Aryee MJ, Joung JK.

Nat Biotechnol. 2019 Sep;37(9):1041-1048. doi: 10.1038/s41587-019-0236-6. Epub 2019 Sep 2.

PMID:
31477922
2.

Droplet-based combinatorial indexing for massive-scale single-cell chromatin accessibility.

Lareau CA, Duarte FM, Chew JG, Kartha VK, Burkett ZD, Kohlway AS, Pokholok D, Aryee MJ, Steemers FJ, Lebofsky R, Buenrostro JD.

Nat Biotechnol. 2019 Aug;37(8):916-924. doi: 10.1038/s41587-019-0147-6. Epub 2019 Jun 24.

PMID:
31235917
3.

Transcriptional States and Chromatin Accessibility Underlying Human Erythropoiesis.

Ludwig LS, Lareau CA, Bao EL, Nandakumar SK, Muus C, Ulirsch JC, Chowdhary K, Buenrostro JD, Mohandas N, An X, Aryee MJ, Regev A, Sankaran VG.

Cell Rep. 2019 Jun 11;27(11):3228-3240.e7. doi: 10.1016/j.celrep.2019.05.046.

4.

Gene-centric functional dissection of human genetic variation uncovers regulators of hematopoiesis.

Nandakumar SK, McFarland SK, Mateyka LM, Lareau CA, Ulirsch JC, Ludwig LS, Agarwal G, Engreitz JM, Przychodzen B, McConkey M, Cowley GS, Doench JG, Maciejewski JP, Ebert BL, Root DE, Sankaran VG.

Elife. 2019 May 9;8. pii: e44080. doi: 10.7554/eLife.44080.

5.

Single-cell trajectories reconstruction, exploration and mapping of omics data with STREAM.

Chen H, Albergante L, Hsu JY, Lareau CA, Lo Bosco G, Guan J, Zhou S, Gorban AN, Bauer DE, Aryee MJ, Langenau DM, Zinovyev A, Buenrostro JD, Yuan GC, Pinello L.

Nat Commun. 2019 Apr 23;10(1):1903. doi: 10.1038/s41467-019-09670-4.

6.

Transcriptome-wide off-target RNA editing induced by CRISPR-guided DNA base editors.

Grünewald J, Zhou R, Garcia SP, Iyer S, Lareau CA, Aryee MJ, Joung JK.

Nature. 2019 May;569(7756):433-437. doi: 10.1038/s41586-019-1161-z. Epub 2019 Apr 17.

7.

Impaired human hematopoiesis due to a cryptic intronic GATA1 splicing mutation.

Abdulhay NJ, Fiorini C, Verboon JM, Ludwig LS, Ulirsch JC, Zieger B, Lareau CA, Mi X, Roy A, Obeng EA, Erlacher M, Gupta N, Gabriel SB, Ebert BL, Niemeyer CM, Khoriaty RN, Ancliff P, Gazda HT, Wlodarski MW, Sankaran VG.

J Exp Med. 2019 May 6;216(5):1050-1060. doi: 10.1084/jem.20181625. Epub 2019 Mar 26.

8.

The ATPase module of mammalian SWI/SNF family complexes mediates subcomplex identity and catalytic activity-independent genomic targeting.

Pan J, McKenzie ZM, D'Avino AR, Mashtalir N, Lareau CA, St Pierre R, Wang L, Shilatifard A, Kadoch C.

Nat Genet. 2019 Apr;51(4):618-626. doi: 10.1038/s41588-019-0363-5. Epub 2019 Mar 11.

9.

Interrogation of human hematopoiesis at single-cell and single-variant resolution.

Ulirsch JC, Lareau CA, Bao EL, Ludwig LS, Guo MH, Benner C, Satpathy AT, Kartha VK, Salem RM, Hirschhorn JN, Finucane HK, Aryee MJ, Buenrostro JD, Sankaran VG.

Nat Genet. 2019 Apr;51(4):683-693. doi: 10.1038/s41588-019-0362-6. Epub 2019 Mar 11.

10.

Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics.

Ludwig LS, Lareau CA, Ulirsch JC, Christian E, Muus C, Li LH, Pelka K, Ge W, Oren Y, Brack A, Law T, Rodman C, Chen JH, Boland GM, Hacohen N, Rozenblatt-Rosen O, Aryee MJ, Buenrostro JD, Regev A, Sankaran VG.

Cell. 2019 Mar 7;176(6):1325-1339.e22. doi: 10.1016/j.cell.2019.01.022. Epub 2019 Feb 28.

PMID:
30827679
11.

Preprocessing and Computational Analysis of Single-Cell Epigenomic Datasets.

Lareau C, Kangeyan D, Aryee MJ.

Methods Mol Biol. 2019;1935:187-202. doi: 10.1007/978-1-4939-9057-3_13.

PMID:
30758828
12.

The cis-Regulatory Atlas of the Mouse Immune System.

Yoshida H, Lareau CA, Ramirez RN, Rose SA, Maier B, Wroblewska A, Desland F, Chudnovskiy A, Mortha A, Dominguez C, Tellier J, Kim E, Dwyer D, Shinton S, Nabekura T, Qi Y, Yu B, Robinette M, Kim KW, Wagers A, Rhoads A, Nutt SL, Brown BD, Mostafavi S, Buenrostro JD, Benoist C; Immunological Genome Project.

Cell. 2019 Feb 7;176(4):897-912.e20. doi: 10.1016/j.cell.2018.12.036. Epub 2019 Jan 24.

PMID:
30686579
13.

Heritability of fetal hemoglobin, white cell count, and other clinical traits from a sickle cell disease family cohort.

Bao EL, Lareau CA, Brugnara C, Fulcher IR, Barau C, Moutereau S, Habibi A, Badaoui B, Berkenou J, Bartolucci P, Galactéros F, Platt OS, Mahaney M, Sankaran VG.

Am J Hematol. 2019 May;94(5):522-527. doi: 10.1002/ajh.25421. Epub 2019 Feb 6.

PMID:
30680775
14.

A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation.

Michel BC, D'Avino AR, Cassel SH, Mashtalir N, McKenzie ZM, McBride MJ, Valencia AM, Zhou Q, Bocker M, Soares LMM, Pan J, Remillard DI, Lareau CA, Zullow HJ, Fortoul N, Gray NS, Bradner JE, Chan HM, Kadoch C.

Nat Cell Biol. 2018 Dec;20(12):1410-1420. doi: 10.1038/s41556-018-0221-1. Epub 2018 Nov 5.

15.

Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks.

Pelikan RC, Kelly JA, Fu Y, Lareau CA, Tessneer KL, Wiley GB, Wiley MM, Glenn SB, Harley JB, Guthridge JM, James JA, Aryee MJ, Montgomery C, Gaffney PM.

Nat Commun. 2018 Jul 25;9(1):2905. doi: 10.1038/s41467-018-05328-9.

16.

Integrated Single-Cell Analysis Maps the Continuous Regulatory Landscape of Human Hematopoietic Differentiation.

Buenrostro JD, Corces MR, Lareau CA, Wu B, Schep AN, Aryee MJ, Majeti R, Chang HY, Greenleaf WJ.

Cell. 2018 May 31;173(6):1535-1548.e16. doi: 10.1016/j.cell.2018.03.074. Epub 2018 Apr 26.

17.

Transcript-indexed ATAC-seq for precision immune profiling.

Satpathy AT, Saligrama N, Buenrostro JD, Wei Y, Wu B, Rubin AJ, Granja JM, Lareau CA, Li R, Qi Y, Parker KR, Mumbach MR, Serratelli WS, Gennert DG, Schep AN, Corces MR, Khodadoust MS, Kim YH, Khavari PA, Greenleaf WJ, Davis MM, Chang HY.

Nat Med. 2018 May;24(5):580-590. doi: 10.1038/s41591-018-0008-8. Epub 2018 Apr 23.

18.

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.

Finucane HK, Reshef YA, Anttila V, Slowikowski K, Gusev A, Byrnes A, Gazal S, Loh PR, Lareau C, Shoresh N, Genovese G, Saunders A, Macosko E, Pollack S; Brainstorm Consortium, Perry JRB, Buenrostro JD, Bernstein BE, Raychaudhuri S, McCarroll S, Neale BM, Price AL.

Nat Genet. 2018 Apr;50(4):621-629. doi: 10.1038/s41588-018-0081-4. Epub 2018 Apr 9.

19.

Response to "Unexpected mutations after CRISPR-Cas9 editing in vivo".

Lareau CA, Clement K, Hsu JY, Pattanayak V, Joung JK, Aryee MJ, Pinello L.

Nat Methods. 2018 Apr;15(4):238-239. doi: 10.1038/nmeth.4541. Epub 2018 Mar 30. No abstract available.

PMID:
29600992
20.

hichipper: a preprocessing pipeline for calling DNA loops from HiChIP data.

Lareau CA, Aryee MJ.

Nat Methods. 2018 Feb 28;15(3):155-156. doi: 10.1038/nmeth.4583. No abstract available.

PMID:
29489746
21.

Common genes associated with antidepressant response in mouse and man identify key role of glucocorticoid receptor sensitivity.

Carrillo-Roa T, Labermaier C, Weber P, Herzog DP, Lareau C, Santarelli S, Wagner KV, Rex-Haffner M, Harbich D, Scharf SH, Nemeroff CB, Dunlop BW, Craighead WE, Mayberg HS, Schmidt MV, Uhr M, Holsboer F, Sillaber I, Binder EB, Müller MB.

PLoS Biol. 2017 Dec 28;15(12):e2002690. doi: 10.1371/journal.pbio.2002690. eCollection 2017 Dec.

22.

A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas.

Ryan RJH, Petrovic J, Rausch DM, Zhou Y, Lareau CA, Kluk MJ, Christie AL, Lee WY, Tarjan DR, Guo B, Donohue LKH, Gillespie SM, Nardi V, Hochberg EP, Blacklow SC, Weinstock DM, Faryabi RB, Bernstein BE, Aster JC, Pear WS.

Cell Rep. 2017 Oct 17;21(3):784-797. doi: 10.1016/j.celrep.2017.09.066.

23.

diffloop: a computational framework for identifying and analyzing differential DNA loops from sequencing data.

Lareau CA, Aryee MJ.

Bioinformatics. 2018 Feb 15;34(4):672-674. doi: 10.1093/bioinformatics/btx623.

24.

Dissecting hematopoietic and renal cell heterogeneity in adult zebrafish at single-cell resolution using RNA sequencing.

Tang Q, Iyer S, Lobbardi R, Moore JC, Chen H, Lareau C, Hebert C, Shaw ML, Neftel C, Suva ML, Ceol CJ, Bernards A, Aryee M, Pinello L, Drummond IA, Langenau DM.

J Exp Med. 2017 Oct 2;214(10):2875-2887. doi: 10.1084/jem.20170976. Epub 2017 Sep 6.

25.

Confounding in ex vivo models of Diamond-Blackfan anemia.

Ulirsch JC, Lareau C, Ludwig LS, Mohandas N, Nathan DG, Sankaran VG.

Blood. 2017 Aug 31;130(9):1165-1168. doi: 10.1182/blood-2017-05-783191. Epub 2017 Jun 14. No abstract available.

26.

Operative Treatment of Traumatic Hallux Valgus in Elite Athletes.

Covell DJ, Lareau CR, Anderson RB.

Foot Ankle Int. 2017 Jun;38(6):590-595. doi: 10.1177/1071100717697961. Epub 2017 Mar 23.

PMID:
28335617
27.

Polygenic risk assessment reveals pleiotropy between sarcoidosis and inflammatory disorders in the context of genetic ancestry.

Lareau CA, DeWeese CF, Adrianto I, Lessard CJ, Gaffney PM, Iannuzzi MC, Rybicki BA, Levin AM, Montgomery CG.

Genes Immun. 2017 Mar;18(2):88-94. doi: 10.1038/gene.2017.3. Epub 2017 Mar 9.

28.

The Integration of Epistasis Network and Functional Interactions in a GWAS Implicates RXR Pathway Genes in the Immune Response to Smallpox Vaccine.

McKinney BA, Lareau C, Oberg AL, Kennedy RB, Ovsyannikova IG, Poland GA.

PLoS One. 2016 Aug 11;11(8):e0158016. doi: 10.1371/journal.pone.0158016. eCollection 2016.

29.

Jones Fractures: Pathophysiology and Treatment.

Lareau CR, Anderson RB.

JBJS Rev. 2015 Jul 28;3(7). pii: 01874474-201503070-00004. doi: 10.2106/JBJS.RVW.N.00100. No abstract available.

PMID:
27490145
30.

An interaction quantitative trait loci tool implicates epistatic functional variants in an apoptosis pathway in smallpox vaccine eQTL data.

Lareau CA, White BC, Oberg AL, Kennedy RB, Poland GA, McKinney BA.

Genes Immun. 2016 Jun;17(4):244-50. doi: 10.1038/gene.2016.15. Epub 2016 Apr 7.

PMID:
27052692
31.

Tibialis Posterior Tendon Entrapment Within Posterior Malleolar Fracture Fragment.

Fantry A, Lareau C, Vopat B, Blankenhorn B.

Am J Orthop (Belle Mead NJ). 2016 Mar-Apr;45(3):E103-7. Review.

PMID:
26991573
32.

Use of a Pneumatic Limb Positioner for Invasive Skeletal Traction in Posterior Hindfoot Arthroscopy.

Vopat BG, Lareau CR, Sangal RB, Fantry AJ, Blankenhorn BD.

Arthrosc Tech. 2015 Sep 7;4(5):e417-22. doi: 10.1016/j.eats.2015.03.020. eCollection 2015 Oct.

33.

dcVar: a method for identifying common variants that modulate differential correlation structures in gene expression data.

Lareau CA, White BC, Montgomery CG, McKinney BA.

Front Genet. 2015 Oct 19;6:312. doi: 10.3389/fgene.2015.00312. eCollection 2015.

34.

Fine mapping of chromosome 15q25 implicates ZNF592 in neurosarcoidosis patients.

Lareau CA, Adrianto I, Levin AM, Iannuzzi MC, Rybicki BA, Montgomery CG.

Ann Clin Transl Neurol. 2015 Oct;2(10):972-7. doi: 10.1002/acn3.229. Epub 2015 Jul 31.

35.

Attorney work product privilege trumps mandated child abuse reporting law: The case of Elijah W. v. Superior Court.

Lareau CR.

Int J Law Psychiatry. 2015 Sep-Dec;42-43:43-8. doi: 10.1016/j.ijlp.2015.08.006. Epub 2015 Sep 26.

PMID:
26404507
36.

Return to Play in National Football League Players After Operative Jones Fracture Treatment.

Lareau CR, Hsu AR, Anderson RB.

Foot Ankle Int. 2016 Jan;37(1):8-16. doi: 10.1177/1071100715603983. Epub 2015 Sep 9.

PMID:
26353796
37.

Does autogenous bone graft work? A logistic regression analysis of data from 159 papers in the foot and ankle literature.

Lareau CR, Deren ME, Fantry A, Donahue RM, DiGiovanni CW.

Foot Ankle Surg. 2015 Sep;21(3):150-9. doi: 10.1016/j.fas.2015.03.008. Epub 2015 Apr 8. Review.

PMID:
26235852
38.

Hybrid Anterolateral Approach for Open Reduction and Internal Fixation of Femoral Neck Fractures.

Vopat BG, Daniels AH, Lareau CR, Christino MA, Kane PM, Hayda RA, Born CT.

Orthopedics. 2015 Jul 1;38(7):430-4. doi: 10.3928/01477447-20150701-03.

PMID:
26186310
39.

Repair of Acute Superficial Deltoid Complex Avulsion During Ankle Fracture Fixation in National Football League Players.

Hsu AR, Lareau CR, Anderson RB.

Foot Ankle Int. 2015 Nov;36(11):1272-8. doi: 10.1177/1071100715593374. Epub 2015 Jul 9.

PMID:
26160387
40.

Divergent elbow dislocation and risk of compartment syndrome.

Mansuripur PK, Deren ME, Lareau CR, Eberson CP.

R I Med J (2013). 2015 May 1;98(5):25-7.

PMID:
25938402
41.

Emergency department external fixation for provisional treatment of pilon and unstable ankle fractures.

Lareau CR, Daniels AH, Vopat BG, Kane PM.

J Emerg Trauma Shock. 2015 Jan-Mar;8(1):61-4. doi: 10.4103/0974-2700.150400.

42.

Differential co-expression network centrality and machine learning feature selection for identifying susceptibility hubs in networks with scale-free structure.

Lareau CA, White BC, Oberg AL, McKinney BA.

BioData Min. 2015 Feb 3;8:5. doi: 10.1186/s13040-015-0040-x. eCollection 2015.

43.

Intra-articular Placement of an Intraosseous Catheter.

Grabel Z, DePasse JM, Lareau CR, Born CT, Daniels AH.

Prehosp Disaster Med. 2015 Feb;30(1):89-92. doi: 10.1017/S1049023X14001290. Epub 2014 Dec 8.

PMID:
25483729
44.

Network theory for data-driven epistasis networks.

Lareau CA, McKinney BA.

Methods Mol Biol. 2015;1253:285-300. doi: 10.1007/978-1-4939-2155-3_15.

PMID:
25403538
45.

Contribution of the medial malleolus to tibiotalar joint contact characteristics.

Lareau CR, Bariteau JT, Paller DJ, Koruprolu SC, DiGiovanni CW.

Foot Ankle Spec. 2015 Feb;8(1):23-8. doi: 10.1177/1938640014546862. Epub 2014 Aug 19.

PMID:
25142917
46.

The Effect of C-Arm Position on Radiation Exposure During Fixation of Pediatric Supracondylar Fractures of the Humerus.

Hsu RY, Lareau CR, Kim JS, Koruprolu S, Born CT, Schiller JR.

J Bone Joint Surg Am. 2014 Aug 6;96(15):e129.

PMID:
25100782
47.

Preoperative cognitive impairment and psychological distress in hospitalized elderly hip fracture patients.

Daniels AH, Daiello LA, Lareau CR, Robidoux KA, Luo W, Ott B, Hayda RA, Born CT.

Am J Orthop (Belle Mead NJ). 2014 Jul;43(7):E146-52.

PMID:
25046191
48.

Plantar and medial heel pain: diagnosis and management.

Lareau CR, Sawyer GA, Wang JH, DiGiovanni CW.

J Am Acad Orthop Surg. 2014 Jun;22(6):372-80. doi: 10.5435/JAAOS-22-06-372. Review.

PMID:
24860133
49.

A biomechanical evaluation of locked plating for distal fibula fractures in an osteoporotic sawbone model.

Bariteau JT, Fantry A, Blankenhorn B, Lareau C, Paller D, Digiovanni CW.

Foot Ankle Surg. 2014 Mar;20(1):44-7. doi: 10.1016/j.fas.2013.10.004. Epub 2013 Nov 13.

PMID:
24480499
50.

Comparative study of scarf and extended chevron osteotomies for correction of hallux valgus.

Vopat BG, Lareau CR, Johnson J, Reinert SE, DiGiovanni CW.

Foot Ankle Spec. 2013 Dec;6(6):409-16. doi: 10.1177/1938640013508431. Epub 2013 Oct 23.

PMID:
24154993

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