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Items: 1 to 50 of 68

1.

Macrophage-B Cell Interactions in the Inverted Porcine Lymph Node and Their Response to Porcine Reproductive and Respiratory Syndrome Virus.

Bordet E, Frétaud M, Crisci E, Bouguyon E, Rault S, Pezant J, Pleau A, Renson P, Giuffra E, Larcher T, Bourge M, Bourry O, Boulesteix O, Langevin C, Schwartz-Cornil I, Bertho N.

Front Immunol. 2019 May 3;10:953. doi: 10.3389/fimmu.2019.00953. eCollection 2019.

2.

A large collection of integrated genomically characterized patient-derived xenografts highlighting the heterogeneity of triple-negative breast cancer.

Coussy F, de Koning L, Lavigne M, Bernard V, Ouine B, Boulai A, El Botty R, Dahmani A, Montaudon E, Assayag F, Morisset L, Huguet L, Sourd L, Painsec P, Callens C, Chateau-Joubert S, Servely JL, Larcher T, Reyes C, Girard E, Pierron G, Laurent C, Vacher S, Baulande S, Melaabi S, Vincent-Salomon A, Gentien D, Dieras V, Bieche I, Marangoni E.

Int J Cancer. 2019 Mar 12. doi: 10.1002/ijc.32266. [Epub ahead of print]

PMID:
30859564
3.

Assessment of pulmonary tissue responses in pigs challenged with PRRSV Lena strain shows better protection after immunization with field than vaccine strains.

Larcher T, Fablet C, Renson P, Ménard D, Hervet C, Saade G, Belloc C, Bourry O, Meurens F.

Vet Microbiol. 2019 Mar;230:249-259. doi: 10.1016/j.vetmic.2019.01.022. Epub 2019 Feb 14.

PMID:
30827397
4.

Five Years of Successful Inducible Transgene Expression Following Locoregional Adeno-Associated Virus Delivery in Nonhuman Primates with no Detectable Immunity.

Guilbaud M, Devaux M, Couzinié C, Le Duff J, Toromanoff A, Vandamme C, Jaulin N, Gernoux G, Larcher T, Moullier P, Le Guiner C, Adjali O.

Hum Gene Ther. 2019 Apr 16. doi: 10.1089/hum.2018.234. [Epub ahead of print]

PMID:
30808235
5.

Oxythermal window drastically constraints the survival and development of European sturgeon early life phases.

Delage N, Couturier B, Jatteau P, Larcher T, Ledevin M, Goubin H, Cachot J, Rochard E.

Environ Sci Pollut Res Int. 2019 Jan 10. doi: 10.1007/s11356-018-4021-8. [Epub ahead of print]

PMID:
30632040
6.

Satellite cells fail to contribute to muscle repair but are functional in Pompe disease (glycogenosis type II).

Lagalice L, Pichon J, Gougeon E, Soussi S, Deniaud J, Ledevin M, Maurier V, Leroux I, Durand S, Ciron C, Franzoso F, Dubreil L, Larcher T, Rouger K, Colle MA.

Acta Neuropathol Commun. 2018 Oct 31;6(1):116. doi: 10.1186/s40478-018-0609-y.

7.

VEGF-A Inhibition as a Potential Therapeutic Approach in Merkel Cell Carcinoma.

Kervarrec T, Gaboriaud P, Tallet A, Leblond V, Arnold F, Berthon P, Schweinitzer S, Larcher T, Guyétant S, Schrama D, Houben R, Samimi M, Touzé A.

J Invest Dermatol. 2019 Mar;139(3):736-739. doi: 10.1016/j.jid.2018.08.029. Epub 2018 Oct 22. No abstract available.

PMID:
30359576
8.

Exploring multiple effects of Zn0.15Mg0.85O nanoparticles on Bacillus subtilis and macrophages.

Auger S, Henry C, Péchoux C, Suman S, Lejal N, Bertho N, Larcher T, Stankic S, Vidic J.

Sci Rep. 2018 Aug 16;8(1):12276. doi: 10.1038/s41598-018-30719-9.

9.

Vascular Delivery of Allogeneic MuStem Cells in Dystrophic Dogs Requires Only Short-Term Immunosuppression to Avoid Host Immunity and Generate Clinical/Tissue Benefits.

Lorant J, Larcher T, Jaulin N, Hedan B, Lardenois A, Leroux I, Dubreil L, Ledevin M, Goubin H, Moullec S, Deschamps JY, Thorin C, André C, Adjali O, Rouger K.

Cell Transplant. 2018 Jul;27(7):1096-1110. doi: 10.1177/0963689718776306. Epub 2018 Jun 5.

10.

Atrophy of primary lymphoid organs induced by Marek's disease virus during early infection is associated with increased apoptosis, inhibition of cell proliferation and a severe B-lymphopenia.

Berthault C, Larcher T, Härtle S, Vautherot JF, Trapp-Fragnet L, Denesvre C.

Vet Res. 2018 Mar 27;49(1):31. doi: 10.1186/s13567-018-0526-x.

11.

Major contribution of the RNA-binding domain of NS1 in the pathogenicity and replication potential of an avian H7N1 influenza virus in chickens.

Trapp S, Soubieux D, Lidove A, Esnault E, Lion A, Guillory V, Wacquiez A, Kut E, Quéré P, Larcher T, Ledevin M, Nadan V, Camus-Bouclainville C, Marc D.

Virol J. 2018 Mar 27;15(1):55. doi: 10.1186/s12985-018-0960-4.

12.

Both Systemic and Intra-articular Immunization with Citrullinated Peptides Are Needed to Induce Arthritis in the Macaque.

Bitoun S, Roques P, Larcher T, Nocturne G, Serguera C, Chrétien P, Serre G, Grand RL, Mariette X.

Front Immunol. 2017 Dec 20;8:1816. doi: 10.3389/fimmu.2017.01816. eCollection 2017.

13.

Fish Reproduction Is Disrupted upon Lifelong Exposure to Environmental PAHs Fractions Revealing Different Modes of Action.

Vignet C, Larcher T, Davail B, Joassard L, Le Menach K, Guionnet T, Lyphout L, Ledevin M, Goubeau M, Budzinski H, Bégout ML, Cousin X.

Toxics. 2016 Oct 28;4(4). pii: E26. doi: 10.3390/toxics4040026.

14.

Epicutaneous Tolerance Induction to a Bystander Antigen Abrogates Colitis and Ileitis in Mice.

Dunkin D, Berin MC, Mondoulet L, Tobar S, Yeretssian G, Tordesillas L, Iuga A, Larcher T, Guillespie V, Benhamou PH, Colombel JF, Sampson HA.

Inflamm Bowel Dis. 2017 Nov;23(11):1972-1982. doi: 10.1097/MIB.0000000000001273.

15.

Treatment of gastric eosinophilia by epicutaneous immunotherapy in piglets sensitized to peanuts.

Mondoulet L, Kalach N, Dhelft V, Larcher T, Delayre-Orthez C, Benhamou PH, Spergel J, Sampson HA, Dupont C.

Clin Exp Allergy. 2017 Dec;47(12):1640-1647. doi: 10.1111/cea.13037. Epub 2017 Oct 20.

PMID:
28960628
16.

Long-term microdystrophin gene therapy is effective in a canine model of Duchenne muscular dystrophy.

Le Guiner C, Servais L, Montus M, Larcher T, Fraysse B, Moullec S, Allais M, François V, Dutilleul M, Malerba A, Koo T, Thibaut JL, Matot B, Devaux M, Le Duff J, Deschamps JY, Barthelemy I, Blot S, Testault I, Wahbi K, Ederhy S, Martin S, Veron P, Georger C, Athanasopoulos T, Masurier C, Mingozzi F, Carlier P, Gjata B, Hogrel JY, Adjali O, Mavilio F, Voit T, Moullier P, Dickson G.

Nat Commun. 2017 Jul 25;8:16105. doi: 10.1038/ncomms16105.

17.

A Short Double-Stapled Peptide Inhibits Respiratory Syncytial Virus Entry and Spreading.

Gaillard V, Galloux M, Garcin D, Eléouët JF, Le Goffic R, Larcher T, Rameix-Welti MA, Boukadiri A, Héritier J, Segura JM, Baechler E, Arrell M, Mottet-Osman G, Nyanguile O.

Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02241-16. doi: 10.1128/AAC.02241-16. Print 2017 Apr.

18.

Characterisation of Early-Life Fecal Microbiota in Susceptible and Healthy Pigs to Post-Weaning Diarrhoea.

Dou S, Gadonna-Widehem P, Rome V, Hamoudi D, Rhazi L, Lakhal L, Larcher T, Bahi-Jaber N, Pinon-Quintana A, Guyonvarch A, Huërou-Luron IL, Abdennebi-Najar L.

PLoS One. 2017 Jan 10;12(1):e0169851. doi: 10.1371/journal.pone.0169851. eCollection 2017.

19.

Altered DNA methylation associated with an abnormal liver phenotype in a cattle model with a high incidence of perinatal pathologies.

Kiefer H, Jouneau L, Campion É, Rousseau-Ralliard D, Larcher T, Martin-Magniette ML, Balzergue S, Ledevin M, Prézelin A, Chavatte-Palmer P, Heyman Y, Richard C, Le Bourhis D, Renard JP, Jammes H.

Sci Rep. 2016 Dec 13;6:38869. doi: 10.1038/srep38869.

20.

Non-invasive epicutaneous vaccine against Respiratory Syncytial Virus: Preclinical proof of concept.

Hervé PL, Descamps D, Deloizy C, Dhelft V, Laubreton D, Bouguyon E, Boukadiri A, Dubuquoy C, Larcher T, Benhamou PH, Eléouët JF, Bertho N, Mondoulet L, Riffault S.

J Control Release. 2016 Dec 10;243:146-159. doi: 10.1016/j.jconrel.2016.10.003. Epub 2016 Oct 6.

21.

Effects of pyrolytic and petrogenic polycyclic aromatic hydrocarbons on swimming and metabolic performance of zebrafish contaminated by ingestion.

Lucas J, Percelay I, Larcher T, Lefrançois C.

Ecotoxicol Environ Saf. 2016 Oct;132:145-52. doi: 10.1016/j.ecoenv.2016.05.035. Epub 2016 Jun 15.

PMID:
27318196
22.

Quantitative proteome profiling of dystrophic dog skeletal muscle reveals a stabilized muscular architecture and protection against oxidative stress after systemic delivery of MuStem cells.

Lardenois A, Jagot S, Lagarrigue M, Guével B, Ledevin M, Larcher T, Dubreil L, Pineau C, Rouger K, Guével L.

Proteomics. 2016 Jul;16(14):2028-42. doi: 10.1002/pmic.201600002.

23.

Identification in GRMD dog muscle of critical miRNAs involved in pathophysiology and effects associated with MuStem cell transplantation.

Robriquet F, Babarit C, Larcher T, Dubreil L, Ledevin M, Goubin H, Rouger K, Guével L.

BMC Musculoskelet Disord. 2016 May 11;17:209. doi: 10.1186/s12891-016-1060-5.

24.

Antioxidant properties of formula derived Maillard reaction products in colons of intrauterine growth restricted pigs.

Elmhiri G, Hamoudi D, Dou S, Bahi-Jaber N, Reygnier J, Larcher T, Firmin S, Abdennebi-Najar L.

Food Funct. 2016 Jun 15;7(6):2582-90. doi: 10.1039/c5fo01551k. Epub 2016 Apr 28.

PMID:
27121180
25.

Infectious Chikungunya Virus in the Saliva of Mice, Monkeys and Humans.

Gardner J, Rudd PA, Prow NA, Belarbi E, Roques P, Larcher T, Gresh L, Balmaseda A, Harris E, Schroder WA, Suhrbier A.

PLoS One. 2015 Oct 8;10(10):e0139481. doi: 10.1371/journal.pone.0139481. eCollection 2015.

26.

In Vivo Evaluation of Cervical Stiffness Evolution during Induced Ripening Using Shear Wave Elastography, Histology and 2 Photon Excitation Microscopy: Insight from an Animal Model.

Peralta L, Mourier E, Richard C, Charpigny G, Larcher T, Aït-Belkacem D, Balla NK, Brasselet S, Tanter M, Muller M, Chavatte-Palmer P.

PLoS One. 2015 Aug 28;10(8):e0133377. doi: 10.1371/journal.pone.0133377. eCollection 2015.

27.

Short-lived recombinant adeno-associated virus transgene expression in dystrophic muscle is associated with oxidative damage to transgene mRNA.

Dupont JB, Tournaire B, Georger C, Marolleau B, Jeanson-Leh L, Ledevin M, Lindenbaum P, Lecomte E, Cogné B, Dubreil L, Larcher T, Gjata B, Van Wittenberghe L, Le Guiner C, Penaud-Budloo M, Snyder RO, Moullier P, Léger A.

Mol Ther Methods Clin Dev. 2015 Apr 8;2:15010. doi: 10.1038/mtm.2015.10. eCollection 2015.

28.

Differential Gene Expression Profiling of Dystrophic Dog Muscle after MuStem Cell Transplantation.

Robriquet F, Lardenois A, Babarit C, Larcher T, Dubreil L, Leroux I, Zuber C, Ledevin M, Deschamps JY, Fromes Y, Cherel Y, Guevel L, Rouger K.

PLoS One. 2015 May 8;10(5):e0123336. doi: 10.1371/journal.pone.0123336. eCollection 2015.

29.

Formula-derived advanced glycation end products are involved in the development of long-term inflammation and oxidative stress in kidney of IUGR piglets.

Elmhiri G, Mahmood DF, Niquet-Leridon C, Jacolot P, Firmin S, Guigand L, Tessier FJ, Larcher T, Abdennebi-Najar L.

Mol Nutr Food Res. 2015 May;59(5):939-47. doi: 10.1002/mnfr.201400722. Epub 2015 Mar 18.

PMID:
25644174
30.

Multiple immune factors are involved in controlling acute and chronic chikungunya virus infection.

Poo YS, Rudd PA, Gardner J, Wilson JA, Larcher T, Colle MA, Le TT, Nakaya HI, Warrilow D, Allcock R, Bielefeldt-Ohmann H, Schroder WA, Khromykh AA, Lopez JA, Suhrbier A.

PLoS Negl Trop Dis. 2014 Dec 4;8(12):e3354. doi: 10.1371/journal.pntd.0003354. eCollection 2014 Dec.

31.

Early interaction of adeno-associated virus serotype 8 vector with the host immune system following intramuscular delivery results in weak but detectable lymphocyte and dendritic cell transduction.

Gernoux G, Guilbaud M, Dubreil L, Larcher T, Babarit C, Ledevin M, Jaulin N, Planel P, Moullier P, Adjali O.

Hum Gene Ther. 2015 Jan;26(1):1-13. doi: 10.1089/hum.2014.070.

PMID:
25333770
32.

Characterization of dystrophin deficient rats: a new model for Duchenne muscular dystrophy.

Larcher T, Lafoux A, Tesson L, Remy S, Thepenier V, François V, Le Guiner C, Goubin H, Dutilleul M, Guigand L, Toumaniantz G, De Cian A, Boix C, Renaud JB, Cherel Y, Giovannangeli C, Concordet JP, Anegon I, Huchet C.

PLoS One. 2014 Oct 13;9(10):e110371. doi: 10.1371/journal.pone.0110371. eCollection 2014.

33.

Forelimb treatment in a large cohort of dystrophic dogs supports delivery of a recombinant AAV for exon skipping in Duchenne patients.

Le Guiner C, Montus M, Servais L, Cherel Y, Francois V, Thibaud JL, Wary C, Matot B, Larcher T, Guigand L, Dutilleul M, Domenger C, Allais M, Beuvin M, Moraux A, Le Duff J, Devaux M, Jaulin N, Guilbaud M, Latournerie V, Veron P, Boutin S, Leborgne C, Desgue D, Deschamps JY, Moullec S, Fromes Y, Vulin A, Smith RH, Laroudie N, Barnay-Toutain F, Rivière C, Bucher S, Le TH, Delaunay N, Gasmi M, Kotin RM, Bonne G, Adjali O, Masurier C, Hogrel JY, Carlier P, Moullier P, Voit T.

Mol Ther. 2014 Nov;22(11):1923-35. doi: 10.1038/mt.2014.151. Epub 2014 Aug 4.

34.

UCP1 is present in porcine adipose tissue and is responsive to postnatal leptin.

Mostyn A, Attig L, Larcher T, Dou S, Chavatte-Palmer P, Boukthir M, Gertler A, Djiane J, E Symonds M, Abdennebi-Najar L.

J Endocrinol. 2014 Oct;223(1):M31-8. doi: 10.1530/JOE-14-0155. Epub 2014 Aug 13.

PMID:
25122002
35.

Maternal high-fat diet induces follicular atresia but does not affect fertility in adult rabbit offspring.

Léveillé P, Tarrade A, Dupont C, Larcher T, Dahirel M, Poumerol E, Cordier AG, Picone O, Mandon-Pepin B, Jolivet G, Lévy R, Chavatte-Palmer P.

J Dev Orig Health Dis. 2014 Apr;5(2):88-97. doi: 10.1017/S2040174414000014.

PMID:
24847695
36.

Chronic dietary exposure of zebrafish to PAH mixtures results in carcinogenic but not genotoxic effects.

Larcher T, Perrichon P, Vignet C, Ledevin M, Le Menach K, Lyphout L, Landi L, Clerandeau C, Lebihanic F, Ménard D, Burgeot T, Budzinski H, Akcha F, Cachot J, Cousin X.

Environ Sci Pollut Res Int. 2014 Dec;21(24):13833-49. doi: 10.1007/s11356-014-2923-7. Epub 2014 Apr 30.

PMID:
24777325
37.

CCR2 deficiency promotes exacerbated chronic erosive neutrophil-dominated chikungunya virus arthritis.

Poo YS, Nakaya H, Gardner J, Larcher T, Schroder WA, Le TT, Major LD, Suhrbier A.

J Virol. 2014 Jun;88(12):6862-72. doi: 10.1128/JVI.03364-13. Epub 2014 Apr 2.

38.

Shortening the unstructured, interdomain region of the non-structural protein NS1 of an avian H1N1 influenza virus increases its replication and pathogenicity in chickens.

Trapp S, Soubieux D, Marty H, Esnault E, Hoffmann TW, Chandenier M, Lion A, Kut E, Quéré P, Larcher T, Ledevin M, Munier S, Naffakh N, Marc D.

J Gen Virol. 2014 Jun;95(Pt 6):1233-43. doi: 10.1099/vir.0.063776-0. Epub 2014 Apr 2.

PMID:
24694396
39.

Effect of experimental infection with Haemonchus contortus on parasitological and local cellular responses in resistant and susceptible young Creole goats.

Bambou JC, Larcher T, Ceï W, Dumoulin PJ, Mandonnet N.

Biomed Res Int. 2013;2013:902759. doi: 10.1155/2013/902759. Epub 2013 Jul 11.

40.

Postnatal leptin promotes organ maturation and development in IUGR piglets.

Attig L, Brisard D, Larcher T, Mickiewicz M, Guilloteau P, Boukthir S, Niamba CN, Gertler A, Djiane J, Monniaux D, Abdennebi-Najar L.

PLoS One. 2013 May 31;8(5):e64616. doi: 10.1371/journal.pone.0064616. Print 2013. Erratum in: PLoS One. 2013;8(9). doi:10.1371/annotation/14e40c23-6fa2-4892-b843-419eb47e4db4.

41.

Dietary lipid and cholesterol induce ovarian dysfunction and abnormal LH response to stimulation in rabbits.

Cordier AG, Léveillé P, Dupont C, Tarrade A, Picone O, Larcher T, Dahirel M, Poumerol E, Mandon-Pepin B, Lévy R, Chavatte-Palmer P.

PLoS One. 2013 May 14;8(5):e63101. doi: 10.1371/journal.pone.0063101. Print 2013.

42.

Histopathological lesions and DNA adducts in the liver of European flounder (Platichthys flesus) collected in the Seine estuary versus two reference estuarine systems on the French Atlantic coast.

Cachot J, Cherel Y, Larcher T, Pfohl-Leszkowicz A, Laroche J, Quiniou L, Morin J, Schmitz J, Burgeot T, Pottier D.

Environ Sci Pollut Res Int. 2013 Feb;20(2):723-37. doi: 10.1007/s11356-012-1287-0. Epub 2012 Nov 17.

PMID:
23161498
43.

Variation patterns in individual fish responses to chemical stress among estuaries, seasons and genders: the case of the European flounder (Platichthys flesus) in the Bay of Biscay.

Laroche J, Gauthier O, Quiniou L, Devaux A, Bony S, Evrard E, Cachot J, Chérel Y, Larcher T, Riso R, Pichereau V, Devier MH, Budzinski H.

Environ Sci Pollut Res Int. 2013 Feb;20(2):738-48. doi: 10.1007/s11356-012-1276-3. Epub 2012 Nov 9.

PMID:
23138562
44.

Validation of BdCCp2 as a marker for Babesia divergens sexual stages in ticks.

Becker CA, Malandrin L, Larcher T, Chauvin A, Bischoff E, Bonnet SI.

Exp Parasitol. 2013 Jan;133(1):51-6. doi: 10.1016/j.exppara.2012.10.007. Epub 2012 Oct 24.

PMID:
23103717
45.

Deletion of the C-terminal ESEV domain of NS1 does not affect the replication of a low-pathogenic avian influenza virus H7N1 in ducks and chickens.

Soubies SM, Hoffmann TW, Croville G, Larcher T, Ledevin M, Soubieux D, Quéré P, Guérin JL, Marc D, Volmer R.

J Gen Virol. 2013 Jan;94(Pt 1):50-8. doi: 10.1099/vir.0.045153-0. Epub 2012 Oct 10.

PMID:
23052391
46.

Interferon response factors 3 and 7 protect against Chikungunya virus hemorrhagic fever and shock.

Rudd PA, Wilson J, Gardner J, Larcher T, Babarit C, Le TT, Anraku I, Kumagai Y, Loo YM, Gale M Jr, Akira S, Khromykh AA, Suhrbier A.

J Virol. 2012 Sep;86(18):9888-98. doi: 10.1128/JVI.00956-12. Epub 2012 Jul 3.

47.

Epicutaneous immunotherapy (EPIT) blocks the allergic esophago-gastro-enteropathy induced by sustained oral exposure to peanuts in sensitized mice.

Mondoulet L, Dioszeghy V, Larcher T, Ligouis M, Dhelft V, Puteaux E, Cherel Y, Letourneur F, Dupont C, Benhamou PH.

PLoS One. 2012;7(2):e31967. doi: 10.1371/journal.pone.0031967. Epub 2012 Feb 21.

48.

Porcine colon explants in the study of innate immune response to Entamoeba histolytica.

Girard-Misguich F, Delgado-Ortega M, Berthon P, Rossignol C, Larcher T, Bruel T, Guibon R, Guillén N, Meurens F.

Vet Immunol Immunopathol. 2012 Feb 15;145(3-4):611-7. doi: 10.1016/j.vetimm.2012.01.002. Epub 2012 Jan 12.

PMID:
22297149
49.

Towards the establishment of a porcine model to study human amebiasis.

Girard-Misguich F, Cognie J, Delgado-Ortega M, Berthon P, Rossignol C, Larcher T, Melo S, Bruel T, Guibon R, Chérel Y, Sarradin P, Salmon H, Guillén N, Meurens F.

PLoS One. 2011;6(12):e28795. doi: 10.1371/journal.pone.0028795. Epub 2011 Dec 21.

50.

Ingenol mebutate field-directed treatment of UVB-damaged skin reduces lesion formation and removes mutant p53 patches.

Cozzi SJ, Ogbourne SM, James C, Rebel HG, de Gruijl FR, Ferguson B, Gardner J, Lee TT, Larcher T, Suhrbier A.

J Invest Dermatol. 2012 Apr;132(4):1263-71. doi: 10.1038/jid.2011.418. Epub 2011 Dec 22.

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