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Items: 22

1.

Deletion of a 19-Amino-Acid Region in Clostridioides difficile TcdB2 Results in Spontaneous Autoprocessing and Reduced Cell Binding and Provides a Nontoxic Immunogen for Vaccination.

Bland SJ, Larabee JL, Shadid TM, Lang ML, Ballard JD.

Infect Immun. 2019 Jul 23;87(8). pii: e00210-19. doi: 10.1128/IAI.00210-19. Print 2019 Aug.

PMID:
31138612
2.

Unique, Intersecting, and Overlapping Roles of C/EBP β and CREB in Cells of the Innate Immune System.

Larabee JL, Hauck G, Ballard JD.

Sci Rep. 2018 Nov 16;8(1):16931. doi: 10.1038/s41598-018-35184-y.

3.

Cell-penetrating peptides derived from Clostridium difficile TcdB2 and a related large clostridial toxin.

Larabee JL, Hauck GD, Ballard JD.

J Biol Chem. 2018 Feb 2;293(5):1810-1819. doi: 10.1074/jbc.M117.815373. Epub 2017 Dec 15.

4.

Amino Acid Differences in the 1753-to-1851 Region of TcdB Influence Variations in TcdB1 and TcdB2 Cell Entry.

Hunt JJ, Larabee JL, Ballard JD.

mSphere. 2017 Aug 2;2(4). pii: e00268-17. doi: 10.1128/mSphere.00268-17. eCollection 2017 Jul-Aug.

5.

Intrinsic Toxin-Derived Peptides Destabilize and Inactivate Clostridium difficile TcdB.

Larabee JL, Bland SJ, Hunt JJ, Ballard JD.

MBio. 2017 May 16;8(3). pii: e00503-17. doi: 10.1128/mBio.00503-17.

6.

Exposure of neutralizing epitopes in the carboxyl-terminal domain of TcdB is altered by a proximal hypervariable region.

Larabee JL, Krumholz A, Hunt JJ, Lanis JM, Ballard JD.

J Biol Chem. 2015 Mar 13;290(11):6975-85. doi: 10.1074/jbc.M114.612184. Epub 2015 Jan 22.

7.

Toxin inhibition of antimicrobial factors induced by Bacillus anthracis peptidoglycan in human blood.

Barua S, Iyer JK, Larabee JL, Raisley B, Hughes MA, Coggeshall KM, Ballard JD.

Infect Immun. 2013 Oct;81(10):3693-702. doi: 10.1128/IAI.00709-13. Epub 2013 Jul 22.

8.

Increased cAMP in monocytes augments Notch signaling mechanisms by elevating RBP-J and transducin-like enhancer of Split (TLE).

Larabee JL, Shakir SM, Barua S, Ballard JD.

J Biol Chem. 2013 Jul 26;288(30):21526-36. doi: 10.1074/jbc.M113.465120. Epub 2013 Jun 17.

9.

Glycogen synthase kinase 3 activation is important for anthrax edema toxin-induced dendritic cell maturation and anthrax toxin receptor 2 expression in macrophages.

Larabee JL, Maldonado-Arocho FJ, Pacheco S, France B, DeGiusti K, Shakir SM, Bradley KA, Ballard JD.

Infect Immun. 2011 Aug;79(8):3302-8. doi: 10.1128/IAI.05070-11. Epub 2011 May 16.

10.

Adenomatous polyposis coli protein associates with C/EBP beta and increases Bacillus anthracis edema toxin-stimulated gene expression in macrophages.

Larabee JL, Shakir SM, Hightower L, Ballard JD.

J Biol Chem. 2011 Jun 3;286(22):19364-72. doi: 10.1074/jbc.M111.224543. Epub 2011 Apr 12.

11.

Systemic molecular and cellular changes induced in rats upon inhalation of JP-8 petroleum fuel vapor.

Hanas JS, Bruce Briggs G, Lerner MR, Lightfoot SA, Larabee JL, Karsies TJ, Epstein RB, Hanas RJ, Brackett DJ, Hocker JR.

Toxicol Mech Methods. 2010 May;20(4):204-12. doi: 10.3109/15376511003681009.

PMID:
20233090
12.

Regulatory interactions of a virulence-associated serine/threonine phosphatase-kinase pair in Bacillus anthracis.

Shakir SM, Bryant KM, Larabee JL, Hamm EE, Lovchik J, Lyons CR, Ballard JD.

J Bacteriol. 2010 Jan;192(2):400-9. doi: 10.1128/JB.01221-09. Epub 2009 Nov 13.

13.

Bacillus anthracis lethal toxin disrupts TCR signaling in CD1d-restricted NKT cells leading to functional anergy.

Joshi SK, Lang GA, Larabee JL, Devera TS, Aye LM, Shah HB, Ballard JD, Lang ML.

PLoS Pathog. 2009 Sep;5(9):e1000588. doi: 10.1371/journal.ppat.1000588. Epub 2009 Sep 25. Erratum in: PLoS Pathog. 2009 Oct;5(10) doi: 10.1371/annotation/cfc9c388-05fa-4b1c-8c5f-99835278a458.

14.

Mechanisms of inhibition of zinc-finger transcription factors by selenium compounds ebselen and selenite.

Larabee JL, Hocker JR, Hanas JS.

J Inorg Biochem. 2009 Mar;103(3):419-26. doi: 10.1016/j.jinorgbio.2008.12.007. Epub 2008 Dec 24.

PMID:
19167089
15.

Bacillus anthracis edema toxin activates nuclear glycogen synthase kinase 3beta.

Larabee JL, DeGiusti K, Regens JL, Ballard JD.

Infect Immun. 2008 Nov;76(11):4895-904. doi: 10.1128/IAI.00889-08. Epub 2008 Sep 2.

16.

Biomarker identification in human pancreatic cancer sera.

Hanas JS, Hocker JR, Cheung JY, Larabee JL, Lerner MR, Lightfoot SA, Morgan DL, Denson KD, Prejeant KC, Gusev Y, Smith BJ, Hanas RJ, Postier RG, Brackett DJ.

Pancreas. 2008 Jan;36(1):61-9. doi: 10.1097/mpa.0b013e3180d0a738.

PMID:
18192883
17.

Serum Profiling of Rat Dermal Exposure to JP-8 Fuel Reveals an Acute-Phase Response.

Larabee JL, Hocker JR, Cheung JY, Gallucci RM, Hanas JS.

Toxicol Mech Methods. 2008;18(1):41-51. doi: 10.1080/15376510701697072.

PMID:
20020890
18.

Effects of endogenous D-alanine synthesis and autoinhibition of Bacillus anthracis germination on in vitro and in vivo infections.

McKevitt MT, Bryant KM, Shakir SM, Larabee JL, Blanke SR, Lovchik J, Lyons CR, Ballard JD.

Infect Immun. 2007 Dec;75(12):5726-34. Epub 2007 Oct 8.

19.

Mechanisms of aurothiomalate-Cys2His2 zinc finger interactions.

Larabee JL, Hocker JR, Hanas JS.

Chem Res Toxicol. 2005 Dec;18(12):1943-54.

PMID:
16359185
20.

Stress induced in heart and other tissues by rat dermal exposure to JP-8 fuel.

Larabee JL, Hocker JR, Lerner MR, Lightfoot SA, Cheung JY, Brackett DJ, Gallucci RM, Hanas JS.

Cell Biol Toxicol. 2005 Sep-Nov;21(5-6):233-46.

PMID:
16323059
21.

Cys redox reactions and metal binding of a Cys2His2 zinc finger.

Larabee JL, Hocker JR, Hanas JS.

Arch Biochem Biophys. 2005 Feb 1;434(1):139-49.

PMID:
15629117
22.

Inhibition of zinc finger protein-DNA interactions by sodium selenite.

Larabee JL, Hocker JR, Hanas RJ, Kahn FM, Hanas JS.

Biochem Pharmacol. 2002 Dec 15;64(12):1757-65.

PMID:
12445865

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