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Items: 14


The Kinesin KIF21B Regulates Microtubule Dynamics and Is Essential for Neuronal Morphology, Synapse Function, and Learning and Memory.

Muhia M, Thies E, Labonté D, Ghiretti AE, Gromova KV, Xompero F, Lappe-Siefke C, Hermans-Borgmeyer I, Kuhl D, Schweizer M, Ohana O, Schwarz JR, Holzbaur ELF, Kneussel M.

Cell Rep. 2016 May 3;15(5):968-977. doi: 10.1016/j.celrep.2016.03.086. Epub 2016 Apr 21.


Neuroligin 1 is dynamically exchanged at postsynaptic sites.

Schapitz IU, Behrend B, Pechmann Y, Lappe-Siefke C, Kneussel SJ, Wallace KE, Stempel AV, Buck F, Grant SG, Schweizer M, Schmitz D, Schwarz JR, Holzbaur EL, Kneussel M.

J Neurosci. 2010 Sep 22;30(38):12733-44. doi: 10.1523/JNEUROSCI.0896-10.2010.


Elevated phosphatidylinositol 3,4,5-trisphosphate in glia triggers cell-autonomous membrane wrapping and myelination.

Goebbels S, Oltrogge JH, Kemper R, Heilmann I, Bormuth I, Wolfer S, Wichert SP, Möbius W, Liu X, Lappe-Siefke C, Rossner MJ, Groszer M, Suter U, Frahm J, Boretius S, Nave KA.

J Neurosci. 2010 Jun 30;30(26):8953-64. doi: 10.1523/JNEUROSCI.0219-10.2010.


The ataxia (axJ) mutation causes abnormal GABAA receptor turnover in mice.

Lappe-Siefke C, Loebrich S, Hevers W, Waidmann OB, Schweizer M, Fehr S, Fritschy JM, Dikic I, Eilers J, Wilson SM, Kneussel M.

PLoS Genet. 2009 Sep;5(9):e1000631. doi: 10.1371/journal.pgen.1000631. Epub 2009 Sep 4.


Synaptic activation modifies microtubules underlying transport of postsynaptic cargo.

Maas C, Belgardt D, Lee HK, Heisler FF, Lappe-Siefke C, Magiera MM, van Dijk J, Hausrat TJ, Janke C, Kneussel M.

Proc Natl Acad Sci U S A. 2009 May 26;106(21):8731-6. doi: 10.1073/pnas.0812391106. Epub 2009 May 13.


Microinjection into cultured hippocampal neurons: a straightforward approach for controlled cellular delivery of nucleic acids, peptides and antibodies.

Lappe-Siefke C, Maas C, Kneussel M.

J Neurosci Methods. 2008 Oct 30;175(1):88-95. doi: 10.1016/j.jneumeth.2008.08.004. Epub 2008 Aug 12.


Axonal loss and neuroinflammation caused by peroxisome-deficient oligodendrocytes.

Kassmann CM, Lappe-Siefke C, Baes M, Brügger B, Mildner A, Werner HB, Natt O, Michaelis T, Prinz M, Frahm J, Nave KA.

Nat Genet. 2007 Aug;39(8):969-76. Epub 2007 Jul 22.


Mice with conditional inactivation of fibroblast growth factor receptor-2 signaling in oligodendrocytes have normal myelin but display dramatic hyperactivity when combined with Cnp1 inactivation.

Kaga Y, Shoemaker WJ, Furusho M, Bryant M, Rosenbluth J, Pfeiffer SE, Oh L, Rasband M, Lappe-Siefke C, Yu K, Ornitz DM, Nave KA, Bansal R.

J Neurosci. 2006 Nov 22;26(47):12339-50.


Neuronal cotransport of glycine receptor and the scaffold protein gephyrin.

Maas C, Tagnaouti N, Loebrich S, Behrend B, Lappe-Siefke C, Kneussel M.

J Cell Biol. 2006 Jan 30;172(3):441-51.


High cholesterol level is essential for myelin membrane growth.

Saher G, Brügger B, Lappe-Siefke C, Möbius W, Tozawa R, Wehr MC, Wieland F, Ishibashi S, Nave KA.

Nat Neurosci. 2005 Apr;8(4):468-75. Epub 2005 Mar 27.


CNP is required for maintenance of axon-glia interactions at nodes of Ranvier in the CNS.

Rasband MN, Tayler J, Kaga Y, Yang Y, Lappe-Siefke C, Nave KA, Bansal R.

Glia. 2005 Apr 1;50(1):86-90.


Cell depletion due to diphtheria toxin fragment A after Cre-mediated recombination.

Brockschnieder D, Lappe-Siefke C, Goebbels S, Boesl MR, Nave KA, Riethmacher D.

Mol Cell Biol. 2004 Sep;24(17):7636-42.


Disruption of Cnp1 uncouples oligodendroglial functions in axonal support and myelination.

Lappe-Siefke C, Goebbels S, Gravel M, Nicksch E, Lee J, Braun PE, Griffiths IR, Nave KA.

Nat Genet. 2003 Mar;33(3):366-74. Epub 2003 Feb 18.


Notch1 control of oligodendrocyte differentiation in the spinal cord.

Genoud S, Lappe-Siefke C, Goebbels S, Radtke F, Aguet M, Scherer SS, Suter U, Nave KA, Mantei N.

J Cell Biol. 2002 Aug 19;158(4):709-18. Epub 2002 Aug 19.

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