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Items: 38


Development and usability testing of a patient decision aid for newly diagnosed relapsing multiple sclerosis patients.

Bansback N, Chiu JA, Carruthers R, Metcalfe R, Lapointe E, Schabas A, Lenzen M, Lynd LD, Traboulsee A.

BMC Neurol. 2019 Jul 20;19(1):173. doi: 10.1186/s12883-019-1382-7.


Three-dimensional MRI sequences in MS diagnosis and research.

Hu XY, Rajendran L, Lapointe E, Tam R, Li D, Traboulsee A, Rauscher A.

Mult Scler. 2019 May 22:1352458519848100. doi: 10.1177/1352458519848100. [Epub ahead of print]


SFRP4 Is a Negative Regulator of Ovarian Follicle Development and Female Fertility.

Zamberlam G, Lapointe E, Abedini A, Rico C, Godin P, Paquet M, DeMayo FJ, Boerboom D.

Endocrinology. 2019 Jul 1;160(7):1561-1572. doi: 10.1210/en.2019-00212.


Longitudinal advanced MRI case report of white matter radiation necrosis.

Wiggermann V, Lapointe E, Litvin L, Graf C, Hernández-Torres E, McKenzie M, Vavasour IM, Laule C, MacMillan EL, Li DKB, Kolind SH, Rauscher A, Traboulsee AL.

Ann Clin Transl Neurol. 2018 Dec 10;6(2):379-385. doi: 10.1002/acn3.704. eCollection 2019 Feb.


Goodpasture's Syndrome Following Alemtuzumab Therapy in Multiple Sclerosis.

Lapointe E, Moghaddam B, Barclay K, Traboulsee AL, Neufeld P.

Can J Neurol Sci. 2018 Nov;45(6):712-714. doi: 10.1017/cjn.2018.325. Epub 2018 Oct 2. No abstract available.


Extracorporeal Stromal Cell Therapy for Subjects With Dialysis-Dependent Acute Kidney Injury.

Miller BLK, Garg P, Bronstein B, LaPointe E, Lin H, Charytan DM, Tilles AW, Parekkadan B.

Kidney Int Rep. 2018 Jun 2;3(5):1119-1127. doi: 10.1016/j.ekir.2018.05.009. eCollection 2018 Sep.


Hypoxia leads to significant changes in alternative splicing and elevated expression of CLK splice factor kinases in PC3 prostate cancer cells.

Bowler E, Porazinski S, Uzor S, Thibault P, Durand M, Lapointe E, Rouschop KMA, Hancock J, Wilson I, Ladomery M.

BMC Cancer. 2018 Apr 2;18(1):355. doi: 10.1186/s12885-018-4227-7.


What Have We Learned from Perfusion MRI in Multiple Sclerosis?

Lapointe E, Li DKB, Traboulsee AL, Rauscher A.

AJNR Am J Neuroradiol. 2018 Jun;39(6):994-1000. doi: 10.3174/ajnr.A5504. Epub 2018 Jan 4. Review.


Splicing arrays reveal novel RBM10 targets, including SMN2 pre-mRNA.

Sutherland LC, Thibault P, Durand M, Lapointe E, Knee JM, Beauvais A, Kalatskaya I, Hunt SC, Loiselle JJ, Roy JG, Tessier SJ, Ybazeta G, Stein L, Kothary R, Klinck R, Chabot B.

BMC Mol Biol. 2017 Jul 20;18(1):19. doi: 10.1186/s12867-017-0096-x.


Transcriptome-wide analysis of alternative RNA splicing events in Epstein-Barr virus-associated gastric carcinomas.

Armero VES, Tremblay MP, Allaire A, Boudreault S, Martenon-Brodeur C, Duval C, Durand M, Lapointe E, Thibault P, Tremblay-Létourneau M, Perreault JP, Scott MS, Bisaillon M.

PLoS One. 2017 May 11;12(5):e0176880. doi: 10.1371/journal.pone.0176880. eCollection 2017.


Temporal Lobe Atrophy May Be Underrecognized in Older Patients with New-Onset Epilepsy.

Lapointe E, Deacon C, Royer-Perron L, Cunnane S, Castellano CA, Bocti C.

Can J Neurol Sci. 2016 Sep;43(5):731-4. doi: 10.1017/cjn.2016.275. No abstract available.


Global Profiling of the Cellular Alternative RNA Splicing Landscape during Virus-Host Interactions.

Boudreault S, Martenon-Brodeur C, Caron M, Garant JM, Tremblay MP, Armero VE, Durand M, Lapointe E, Thibault P, Tremblay-Létourneau M, Perreault JP, Scott MS, Lemay G, Bisaillon M.

PLoS One. 2016 Sep 6;11(9):e0161914. doi: 10.1371/journal.pone.0161914. eCollection 2016.


Global profiling of alternative RNA splicing events provides insights into molecular differences between various types of hepatocellular carcinoma.

Tremblay MP, Armero VE, Allaire A, Boudreault S, Martenon-Brodeur C, Durand M, Lapointe E, Thibault P, Tremblay-Létourneau M, Perreault JP, Scott MS, Bisaillon M.

BMC Genomics. 2016 Aug 26;17:683. doi: 10.1186/s12864-016-3029-z.


WNT5a is required for normal ovarian follicle development and antagonizes gonadotropin responsiveness in granulosa cells by suppressing canonical WNT signaling.

Abedini A, Zamberlam G, Lapointe E, Tourigny C, Boyer A, Paquet M, Hayashi K, Honda H, Kikuchi A, Price C, Boerboom D.

FASEB J. 2016 Apr;30(4):1534-47. doi: 10.1096/fj.15-280313. Epub 2015 Dec 14.


Paraneoplastic neurologic syndromes: clinical presentation and management.

Martel S, De Angelis F, Lapointe E, Larue S, Speranza G.

Curr Probl Cancer. 2014 Jul-Aug;38(4):115-34. doi: 10.1016/j.currproblcancer.2014.08.002. Epub 2014 Aug 6. Review. No abstract available.


RBFOX1 cooperates with MBNL1 to control splicing in muscle, including events altered in myotonic dystrophy type 1.

Klinck R, Fourrier A, Thibault P, Toutant J, Durand M, Lapointe E, Caillet-Boudin ML, Sergeant N, Gourdon G, Meola G, Furling D, Puymirat J, Chabot B.

PLoS One. 2014 Sep 11;9(9):e107324. doi: 10.1371/journal.pone.0107324. eCollection 2014.


HIF1 activity in granulosa cells is required for FSH-regulated Vegfa expression and follicle survival in mice.

Rico C, Dodelet-Devillers A, Paquet M, Tsoi M, Lapointe E, Carmeliet P, Boerboom D.

Biol Reprod. 2014 Jun;90(6):135. doi: 10.1095/biolreprod.113.115634. Epub 2014 May 22.


Redirecting splicing with bifunctional oligonucleotides.

Brosseau JP, Lucier JF, Lamarche AA, Shkreta L, Gendron D, Lapointe E, Thibault P, Paquet E, Perreault JP, Abou Elela S, Chabot B.

Nucleic Acids Res. 2014 Apr;42(6):e40. doi: 10.1093/nar/gkt1287. Epub 2013 Dec 26.


Tumor microenvironment-associated modifications of alternative splicing.

Brosseau JP, Lucier JF, Nwilati H, Thibault P, Garneau D, Gendron D, Durand M, Couture S, Lapointe E, Prinos P, Klinck R, Perreault JP, Chabot B, Abou-Elela S.

RNA. 2014 Feb;20(2):189-201. doi: 10.1261/rna.042168.113. Epub 2013 Dec 11.


RBFOX2 is an important regulator of mesenchymal tissue-specific splicing in both normal and cancer tissues.

Venables JP, Brosseau JP, Gadea G, Klinck R, Prinos P, Beaulieu JF, Lapointe E, Durand M, Thibault P, Tremblay K, Rousset F, Tazi J, Abou Elela S, Chabot B.

Mol Cell Biol. 2013 Jan;33(2):396-405. doi: 10.1128/MCB.01174-12. Epub 2012 Nov 12.


FZD1 regulates cumulus expansion genes and is required for normal female fertility in mice.

Lapointe E, Boyer A, Rico C, Paquet M, Franco HL, Gossen J, DeMayo FJ, Richards JS, Boerboom D.

Biol Reprod. 2012 Nov 1;87(5):104. doi: 10.1095/biolreprod.112.102608. Print 2012 Nov.


Pharmacological targeting of mammalian target of rapamycin inhibits ovarian granulosa cell tumor growth.

Rico C, Laguë MN, Lefèvre P, Tsoi M, Dodelet-Devillers A, Kumar V, Lapointe E, Paquet M, Nadeau MÈ, Boerboom D.

Carcinogenesis. 2012 Nov;33(11):2283-92. doi: 10.1093/carcin/bgs263. Epub 2012 Aug 7.


A multi-view time-domain non-contact diffuse optical tomography scanner with dual wavelength detection for intrinsic and fluorescence small animal imaging.

Lapointe E, Pichette J, Bérubé-Lauzière Y.

Rev Sci Instrum. 2012 Jun;83(6):063703. doi: 10.1063/1.4726016. Review.


Proteins associated with the exon junction complex also control the alternative splicing of apoptotic regulators.

Michelle L, Cloutier A, Toutant J, Shkreta L, Thibault P, Durand M, Garneau D, Gendron D, Lapointe E, Couture S, Le Hir H, Klinck R, Elela SA, Prinos P, Chabot B.

Mol Cell Biol. 2012 Mar;32(5):954-67. doi: 10.1128/MCB.06130-11. Epub 2011 Dec 27.


Partially redundant functions of Adamts1 and Adamts4 in the perinatal development of the renal medulla.

Boerboom D, Lafond JF, Zheng X, Lapointe E, Mittaz L, Boyer A, Pritchard MA, DeMayo FJ, Mort JS, Drolet R, Richards JS.

Dev Dyn. 2011 Jul;240(7):1806-14. doi: 10.1002/dvdy.22662. Epub 2011 May 16.


Alternative splicing of SYK regulates mitosis and cell survival.

Prinos P, Garneau D, Lucier JF, Gendron D, Couture S, Boivin M, Brosseau JP, Lapointe E, Thibault P, Durand M, Tremblay K, Gervais-Bird J, Nwilati H, Klinck R, Chabot B, Perreault JP, Wellinger RJ, Elela SA.

Nat Struct Mol Biol. 2011 Jun;18(6):673-9. doi: 10.1038/nsmb.2040. Epub 2011 May 8.


WNT signaling and the regulation of ovarian steroidogenesis.

Lapointe E, Boerboom D.

Front Biosci (Schol Ed). 2011 Jan 1;3:276-85. Review.


Interview: Ernie LaPointe. Honoring his ancestor by studying his DNA. Interview by John Travis.

LaPointe E.

Science. 2010 Oct 8;330(6001):172. doi: 10.1126/science.330.6001.172-b. No abstract available.


WNT4 is required for normal ovarian follicle development and female fertility.

Boyer A, Lapointe E, Zheng X, Cowan RG, Li H, Quirk SM, DeMayo FJ, Richards JS, Boerboom D.

FASEB J. 2010 Aug;24(8):3010-25. doi: 10.1096/fj.09-145789. Epub 2010 Apr 6.


High-throughput quantification of splicing isoforms.

Brosseau JP, Lucier JF, Lapointe E, Durand M, Gendron D, Gervais-Bird J, Tremblay K, Perreault JP, Elela SA.

RNA. 2010 Feb;16(2):442-9. doi: 10.1261/rna.1877010. Epub 2009 Dec 28.


Cancer-associated regulation of alternative splicing.

Venables JP, Klinck R, Koh C, Gervais-Bird J, Bramard A, Inkel L, Durand M, Couture S, Froehlich U, Lapointe E, Lucier JF, Thibault P, Rancourt C, Tremblay K, Prinos P, Chabot B, Elela SA.

Nat Struct Mol Biol. 2009 Jun;16(6):670-6. doi: 10.1038/nsmb.1608. Epub 2009 May 17.


Identification of alternative splicing markers for breast cancer.

Venables JP, Klinck R, Bramard A, Inkel L, Dufresne-Martin G, Koh C, Gervais-Bird J, Lapointe E, Froehlich U, Durand M, Gendron D, Brosseau JP, Thibault P, Lucier JF, Tremblay K, Prinos P, Wellinger RJ, Chabot B, Rancourt C, Elela SA.

Cancer Res. 2008 Nov 15;68(22):9525-31. doi: 10.1158/0008-5472.CAN-08-1769.


Multiple and specific mRNA processing targets for the major human hnRNP proteins.

Venables JP, Koh CS, Froehlich U, Lapointe E, Couture S, Inkel L, Bramard A, Paquet ER, Watier V, Durand M, Lucier JF, Gervais-Bird J, Tremblay K, Prinos P, Klinck R, Elela SA, Chabot B.

Mol Cell Biol. 2008 Oct;28(19):6033-43. doi: 10.1128/MCB.00726-08. Epub 2008 Jul 21.


[A realized dream. Interview by Charles Meunier].

Lapointe E, Simard S, Plaisance N, Schoos N.

Perspect Infirm. 2008 May-Jun;5(5):20-1. French. No abstract available.


Rheumatoid arthritis specific anti-Sa antibodies target citrullinated vimentin.

Vossenaar ER, Després N, Lapointe E, van der Heijden A, Lora M, Senshu T, van Venrooij WJ, Ménard HA.

Arthritis Res Ther. 2004;6(2):R142-50. Epub 2004 Feb 5.


Angiotensin-converting enzyme inhibitor captopril prevents volume overload cardiomyopathy in experimental chronic aortic valve regurgitation.

Plante E, Gaudreau M, Lachance D, Drolet MC, Roussel E, Gauthier C, Lapointe E, Arsenault M, Couet J.

Can J Physiol Pharmacol. 2004 Mar;82(3):191-9.


Small interfering RNA-mediated reduction in heterogeneous nuclear ribonucleoparticule A1/A2 proteins induces apoptosis in human cancer cells but not in normal mortal cell lines.

Patry C, Bouchard L, Labrecque P, Gendron D, Lemieux B, Toutant J, Lapointe E, Wellinger R, Chabot B.

Cancer Res. 2003 Nov 15;63(22):7679-88.


Insights into rheumatoid arthritis derived from the Sa immune system.

Ménard HA, Lapointe E, Rochdi MD, Zhou ZJ.

Arthritis Res. 2000;2(6):429-32. Epub 2000 Aug 17. Review.

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