Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 251


hCINAP regulates the DNA-damage response and mediates the resistance of acute myelocytic leukemia cells to therapy.

Xu R, Yu S, Zhu D, Huang X, Xu Y, Lao Y, Tian Y, Zhang J, Tang Z, Zhang Z, Yi J, Zhu HH, Zheng X.

Nat Commun. 2019 Aug 23;10(1):3812. doi: 10.1038/s41467-019-11795-5.


Efficacy and safety of siponimod for multiple sclerosis: Protocol for a systematic review and meta-analysis.

Song Y, Lao Y, Liang F, Li J, Jia B, Wang Z, Hui X, Lu Z, Zhou B, Luo W, Song B.

Medicine (Baltimore). 2019 Aug;98(34):e15415. doi: 10.1097/MD.0000000000015415.


SRC and MEK Co-inhibition Synergistically Enhances the Anti-tumor Effect in Both Non-small-cell Lung Cancer (NSCLC) and Erlotinib-Resistant NSCLC.

Yuan M, Xu LF, Zhang J, Kong SY, Wu M, Lao YZ, Zhou H, Zhang L, Xu H.

Front Oncol. 2019 Jul 30;9:586. doi: 10.3389/fonc.2019.00586. eCollection 2019.


Engineering Cell Membrane-Based Nanotherapeutics to Target Inflammation.

Yan H, Shao D, Lao YH, Li M, Hu H, Leong KW.

Adv Sci (Weinh). 2019 May 22;6(15):1900605. doi: 10.1002/advs.201900605. eCollection 2019 Aug 7. Review.


Novel association of five HLA alleles with HIV-1 progression in Spanish long-term non progressor patients.

Ramírez de Arellano E, Díez-Fuertes F, Aguilar F, de la Torre Tarazona HE, Sánchez-Lara S, Lao Y, Vicario JL, García F, González-Garcia J, Pulido F, Gutierrez-Rodero F, Moreno S, Iribarren JA, Viciana P, Vilches C, Ramos M, Capa L, Alcamí J, Del Val M.

PLoS One. 2019 Aug 8;14(8):e0220459. doi: 10.1371/journal.pone.0220459. eCollection 2019.


The Natural Compound Neobractatin Induces Cell Cycle Arrest by Regulating E2F1 and Gadd45α.

Zheng Z, Wu M, Zhang J, Fu W, Xu N, Lao Y, Lin L, Xu H.

Front Oncol. 2019 Jul 17;9:654. doi: 10.3389/fonc.2019.00654. eCollection 2019.


A fine-tuning mechanism underlying self-control for autophagy: deSUMOylation of BECN1 by SENP3.

Liu K, Guo C, Lao Y, Yang J, Chen F, Zhao Y, Yang Y, Yang J, Yi J.

Autophagy. 2019 Aug 2:1-16. doi: 10.1080/15548627.2019.1647944. [Epub ahead of print]


Garcinol inhibits esophageal cancer metastasis by suppressing the p300 and TGF-β1 signaling pathways.

Wang J, Wu M, Zheng D, Zhang H, Lv Y, Zhang L, Tan HS, Zhou H, Lao YZ, Xu HX.

Acta Pharmacol Sin. 2019 Aug 1. doi: 10.1038/s41401-019-0271-3. [Epub ahead of print]


The natural compound neobractatin inhibits tumor metastasis by upregulating the RNA-binding-protein MBNL2.

Zhang J, Zheng Z, Wu M, Zhang L, Wang J, Fu W, Xu N, Zhao Z, Lao Y, Xu H.

Cell Death Dis. 2019 Jul 18;10(8):554. doi: 10.1038/s41419-019-1789-5.


Effect of Sweet Corn Residue on Micronutrient Fortification in Baked Cakes.

Lao YX, Yu YY, Li GK, Chen SY, Li W, Xing XP, Wang XM, Hu JG, Guo XB.

Foods. 2019 Jul 16;8(7). pii: E260. doi: 10.3390/foods8070260.


Uncariitannin, a polyphenolic polymer from Uncaria gambier, attenuates Staphylococcus aureus virulence through an MgrA-mediated regulation of α-hemolysin.

Zhang H, Jiang JM, Han L, Lao YZ, Zheng D, Chen YY, Wan SJ, Zheng CW, Tan HS, Li ZG, Xu HX.

Pharmacol Res. 2019 Jul 6;147:104328. doi: 10.1016/j.phrs.2019.104328. [Epub ahead of print]


Association between alcohol consumption and mild cognitive impairment: A protocol of dose-response meta-analysis.

Hui X, Li J, Lao Y, Jia B, Hou L, Lu Z, Gu Q, Niu J, Bao H, Yan P, Yao L.

Medicine (Baltimore). 2019 Jul;98(27):e16098. doi: 10.1097/MD.0000000000016098.


Alcohol consumption and risk of dementia: A dose-response meta-analysis.

Li J, Hui X, Gu Q, Lao Y, Lu Z, Hou L, Jia B, Niu J, Yao L, Yan P.

Medicine (Baltimore). 2019 Jun;98(26):e16099. doi: 10.1097/MD.0000000000016099.


Discovery of ABT-957: 1-Benzyl-5-oxopyrrolidine-2-carboxamides as selective calpain inhibitors with enhanced metabolic stability.

Jantos K, Kling A, Mack H, Hornberger W, Moeller A, Nimmrich V, Lao Y, Nijsen M.

Bioorg Med Chem Lett. 2019 Aug 1;29(15):1968-1973. doi: 10.1016/j.bmcl.2019.05.034. Epub 2019 May 18.


A modular and concise approach to MIDA acylboronates via chemoselective oxidation of unsymmetrical geminal diborylalkanes: unlocking access to a novel class of acylborons.

Lin S, Wang L, Aminoleslami N, Lao Y, Yagel C, Sharma A.

Chem Sci. 2019 Mar 21;10(17):4684-4691. doi: 10.1039/c9sc00378a. eCollection 2019 May 7.


Methanol content in homemade alcohol from a province in North Vietnam.

Lao Y, Pham BD, Le HT, Nguyen Van H, Hovda KE.

Drug Alcohol Rev. 2019 Jul;38(5):537-542. doi: 10.1111/dar.12937. Epub 2019 May 16.


Molecular Analysis of Evolution and Origins of Cultivated Hawthorn (Crataegus spp.) and Related Species in China.

Du X, Zhang X, Bu H, Zhang T, Lao Y, Dong W.

Front Plant Sci. 2019 Apr 9;10:443. doi: 10.3389/fpls.2019.00443. eCollection 2019.


An Accurate Recognition of Infrared Retro-Reflective Markers in Surgical Navigation.

Wu H, Lin Q, Yang R, Zhou Y, Zheng L, Huang Y, Wang Z, Lao Y, Huang J.

J Med Syst. 2019 Apr 24;43(6):153. doi: 10.1007/s10916-019-1257-x.


Activity-based protein profiling approaches for transplantation.

Navarrete M, Wilkins JA, Lao Y, Rush DN, Nickerson PW, Ho J.

Transplantation. 2019 Apr 8. doi: 10.1097/TP.0000000000002752. [Epub ahead of print]


Multimodal Nutritional Management in Primary Lumbar Spine Surgery: A Randomized Controlled Trial.

Xu B, Xu WX, Lao YJ, Ding WG, Lu D, Sheng HF.

Spine (Phila Pa 1976). 2019 Jul 15;44(14):967-974. doi: 10.1097/BRS.0000000000002992.


Garsubelone A, the First Dimeric Polycyclic Polyprenylated Acylphloroglucinols with Complicated Heptacyclic Architecture from Garcinia subelliptica.

Wang YL, Ye YS, Fu WW, Wu R, Xiang Q, Lao YZ, Yang JL, Tan HS, Yang XW, Yang BC, Xu HX, Xu G.

Org Lett. 2019 Mar 1;21(5):1534-1537. doi: 10.1021/acs.orglett.9b00388. Epub 2019 Feb 18.


Engineered Mesenchymal Stem Cell/Nanomedicine Spheroid as an Active Drug Delivery Platform for Combinational Glioblastoma Therapy.

Suryaprakash S, Lao YH, Cho HY, Li M, Ji HY, Shao D, Hu H, Quek CH, Huang D, Mintz RL, Bagó JR, Hingtgen SD, Lee KB, Leong KW.

Nano Lett. 2019 Mar 13;19(3):1701-1705. doi: 10.1021/acs.nanolett.8b04697. Epub 2019 Feb 21.


Identification of Genes Involved in Low Temperature-Induced Senescence of Panicle Leaf in Litchi chinensis.

Wang C, Liu H, Yu S, Chen H, Hu F, Zhan H, Pan X, Lao Y, Zhong S, Zhou B.

Genes (Basel). 2019 Feb 1;10(2). pii: E111. doi: 10.3390/genes10020111.


A multifunctional mesoporous silica-gold nanocluster hybrid platform for selective breast cancer cell detection using a catalytic amplification-based colorimetric assay.

Li M, Lao YH, Mintz RL, Chen Z, Shao D, Hu H, Wang HX, Tao Y, Leong KW.

Nanoscale. 2019 Feb 7;11(6):2631-2636. doi: 10.1039/c8nr08337a.


A post-processing method based on interphase motion correction and averaging to improve image quality of 4D magnetic resonance imaging: a clinical feasibility study.

Deng Z, Pang J, Lao Y, Bi X, Wang G, Chen Y, Fenchel M, Tuli R, Li D, Yang W, Fan Z.

Br J Radiol. 2019 Mar;92(1095):20180424. doi: 10.1259/bjr.20180424. Epub 2019 Jan 3.


Prognostic Value of Hemoglobin A1c Levels in Postmenopausal Diabetic Patients Undergoing Percutaneous Coronary Intervention (PCI) for Acute Coronary Syndrome.

Lao Y, Feng L, Yuan Y, Zhang J, Huang X, Li M, Wu Z.

Med Sci Monit. 2018 Dec 27;24:9399-9405. doi: 10.12659/MSM.912108.


Nuclear actin switch of the INO80 remodeler.

Wu J, Lao Y, Li B.

J Mol Cell Biol. 2019 May 1;11(5):343-344. doi: 10.1093/jmcb/mjy083. No abstract available.


Erratum: In-Tether Chiral Center Induced Helical Peptide Modulators Target p53-MDM2/MDMX and Inhibit Tumor Growth in Stem-Like Cancer Cell: Erratum.

Hu K, Yin F, Yu M, Sun C, Li J, Liang Y, Li W, Xie M, Lao Y, Liang W, Li ZG.

Theranostics. 2018 Nov 10;8(20):5660-5661. doi: 10.7150/thno.31152. eCollection 2018.


Long noncoding RNA ENST00000455974 plays an oncogenic role through up-regulating JAG2 in human DNA mismatch repair-proficient colon cancer.

Lao Y, Li Q, Li N, Liu H, Liu K, Jiang G, Wei N, Wang C, Wang Y, Wu J.

Biochem Biophys Res Commun. 2019 Jan 8;508(2):339-347. doi: 10.1016/j.bbrc.2018.11.088. Epub 2018 Nov 23.


Discriminating lung adenocarcinoma from lung squamous cell carcinoma using respiration-induced tumor shape changes.

Lao Y, David J, Mirhadi A, Lepore N, Sandler H, Wang Y, Tuli R, Yang W.

Phys Med Biol. 2018 Nov 7;63(21):215027. doi: 10.1088/1361-6560/aae7f1.


Profiles of quorum sensing (QS)-related sequences in phycospheric microorganisms during a marine dinoflagellate bloom, as determined by a metagenomic approach.

Huang X, Zhu J, Cai Z, Lao Y, Jin H, Yu K, Zhang B, Zhou J.

Microbiol Res. 2018 Dec;217:1-13. doi: 10.1016/j.micres.2018.08.015. Epub 2018 Aug 30.


Screening of FDA-approved drugs identifies sutent as a modulator of UCP1 expression in brown adipose tissue.

Qiu Y, Sun Y, Xu D, Yang Y, Liu X, Wei Y, Chen Y, Feng Z, Li S, Reyad-Ul Ferdous M, Zhao Y, Xu H, Lao Y, Ding Q.

EBioMedicine. 2018 Nov;37:344-355. doi: 10.1016/j.ebiom.2018.10.019. Epub 2018 Oct 20.


Oblongifolin C suppresses lysosomal function independently of TFEB nuclear translocation.

Wu M, Lao YZ, Tan HS, Lu G, Ren Y, Zheng ZQ, Yi J, Fu WW, Shen HM, Xu HX.

Acta Pharmacol Sin. 2019 Jul;40(7):929-937. doi: 10.1038/s41401-018-0167-7. Epub 2018 Oct 17.


Tubeimoside-1, a triterpenoid saponin, induces cytoprotective autophagy in human breast cancer cells in vitro via Akt-mediated pathway.

Jiang SL, Guan YD, Chen XS, Ge P, Wang XL, Lao YZ, Xiao SS, Zhang Y, Yang JM, Xu XJ, Cao DS, Cheng Y.

Acta Pharmacol Sin. 2019 Jul;40(7):919-928. doi: 10.1038/s41401-018-0165-9. Epub 2018 Oct 12.


Antibiofilm activity substances derived from coral symbiotic bacterial extract inhibit biofouling by the model strain Pseudomonas aeruginosa PAO1.

Song Y, Cai ZH, Lao YM, Jin H, Ying KZ, Lin GH, Zhou J.

Microb Biotechnol. 2018 Nov;11(6):1090-1105. doi: 10.1111/1751-7915.13312. Epub 2018 Oct 9.


Targeting Endothelial Erk1/2-Akt Axis as a Regeneration Strategy to Bypass Fibrosis during Chronic Liver Injury in Mice.

Lao Y, Li Y, Zhang P, Shao Q, Lin W, Qiu B, Lv Y, Tang L, Su S, Zhang H, Tian C, Sun A, Wei H, Zhang P, Wu Y, Jiang Y, He F.

Mol Ther. 2018 Dec 5;26(12):2779-2797. doi: 10.1016/j.ymthe.2018.08.016. Epub 2018 Aug 24.


Is metformin still the most efficacious first-line oral hypoglycaemic drug in treating type 2 diabetes? A network meta-analysis of randomized controlled trials.

Jia Y, Lao Y, Zhu H, Li N, Leung SW.

Obes Rev. 2019 Jan;20(1):1-12. doi: 10.1111/obr.12753. Epub 2018 Sep 17. Review.


A rapid UHPLC-HILIC method for algal guanosine 5'-diphosphate 3'-diphosphate (ppGpp) and the potential separation mechanism.

Jin H, Lao YM, Zhou J, Zhang HJ, Cai ZH.

J Chromatogr B Analyt Technol Biomed Life Sci. 2018 Oct 1;1096:143-153. doi: 10.1016/j.jchromb.2018.08.009. Epub 2018 Aug 17.


A Novel Hydrolytic Activity of Tri-Functional Geranylgeranyl Pyrophosphate Synthase in Haematococcus pluvialis.

Lao YM, Jin H, Zhou J, Zhang HJ, Zhu XS, Cai ZH.

Plant Cell Physiol. 2018 Dec 1;59(12):2536-2548. doi: 10.1093/pcp/pcy173.


SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation.

Yu X, Lao Y, Teng XL, Li S, Zhou Y, Wang F, Guo X, Deng S, Chang Y, Wu X, Liu Z, Chen L, Lu LM, Cheng J, Li B, Su B, Jiang J, Li HB, Huang C, Yi J, Zou Q.

Nat Commun. 2018 Aug 8;9(1):3157. doi: 10.1038/s41467-018-05676-6.


Discovery of Novel Aminotetralines and Aminochromanes as Selective and Competitive Glycine Transporter 1 (GlyT1) Inhibitors.

Amberg W, Lange UEW, Ochse M, Pohlki F, Behl B, Relo AL, Hornberger W, Hoft C, Mezler M, Sydor J, Wang Y, Zhao H, Brewer JT, Dietrich J, Li H, Akritopoulou-Zanze I, Lao Y, Hannick SM, Ku YY, Vasudevan A.

J Med Chem. 2018 Sep 13;61(17):7503-7524. doi: 10.1021/acs.jmedchem.8b00300. Epub 2018 Aug 27.


HPV Oncogene Manipulation Using Nonvirally Delivered CRISPR/Cas9 or Natronobacterium gregoryi Argonaute.

Lao YH, Li M, Gao MA, Shao D, Chi CW, Huang D, Chakraborty S, Ho TC, Jiang W, Wang HX, Wang S, Leong KW.

Adv Sci (Weinh). 2018 May 18;5(7):1700540. doi: 10.1002/advs.201700540. eCollection 2018 Jul.


De Novo Design, Synthesis, and Biological Evaluation of 3,4-Disubstituted Pyrrolidine Sulfonamides as Potent and Selective Glycine Transporter 1 Competitive Inhibitors.

Wang Y, Zhao H, Brewer JT, Li H, Lao Y, Amberg W, Behl B, Akritopoulou-Zanze I, Dietrich J, Lange UEW, Pohlki F, Hoft C, Hornberger W, Djuric SW, Sydor J, Mezler M, Relo AL, Vasudevan A.

J Med Chem. 2018 Sep 13;61(17):7486-7502. doi: 10.1021/acs.jmedchem.8b00295. Epub 2018 Jul 17.


Bioinspired Diselenide-Bridged Mesoporous Silica Nanoparticles for Dual-Responsive Protein Delivery.

Shao D, Li M, Wang Z, Zheng X, Lao YH, Chang Z, Zhang F, Lu M, Yue J, Hu H, Yan H, Chen L, Dong WF, Leong KW.

Adv Mater. 2018 May 28:e1801198. doi: 10.1002/adma.201801198. [Epub ahead of print]


Anti-infective biomaterials with surface-decorated tachyplesin I.

Xue Q, Liu XB, Lao YH, Wu LP, Wang D, Zuo ZQ, Chen JY, Hou J, Bei YY, Wu XF, Leong KW, Xiang H, Han J.

Biomaterials. 2018 Sep;178:351-362. doi: 10.1016/j.biomaterials.2018.05.008. Epub 2018 May 9.


Natural compound Oblongifolin C confers gemcitabine resistance in pancreatic cancer by downregulating Src/MAPK/ERK pathways.

Li Y, Xi Z, Chen X, Cai S, Liang C, Wang Z, Li Y, Tan H, Lao Y, Xu H.

Cell Death Dis. 2018 May 1;9(5):538. doi: 10.1038/s41419-018-0574-1.


Nonviral gene editing via CRISPR/Cas9 delivery by membrane-disruptive and endosomolytic helical polypeptide.

Wang HX, Song Z, Lao YH, Xu X, Gong J, Cheng D, Chakraborty S, Park JS, Li M, Huang D, Yin L, Cheng J, Leong KW.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):4903-4908. doi: 10.1073/pnas.1712963115. Epub 2018 Apr 23.


Mitigating the Metabolic Liability of Carbonyl Reduction: Novel Calpain Inhibitors with P1' Extension.

Kling A, Jantos K, Mack H, Hornberger W, Backfisch G, Lao Y, Nijsen M, Rendenbach-Mueller B, Moeller A.

ACS Med Chem Lett. 2018 Feb 4;9(3):221-226. doi: 10.1021/acsmedchemlett.7b00494. eCollection 2018 Mar 8.

Supplemental Content

Support Center