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Items: 1 to 50 of 114

1.

Learning across multi-stimulus enhances target recognition methods in SSVEP-based BCIs.

Wong CM, Wan F, Wang B, Wang Z, Nan W, Lao KF, Mak PU, Vai MI, da Rosa AC.

J Neural Eng. 2019 May 21. doi: 10.1088/1741-2552/ab2373. [Epub ahead of print]

PMID:
31112937
2.

Accurate and Efficient ab Initio Calculations for Supramolecular Complexes: Symmetry-Adapted Perturbation Theory with Many-Body Dispersion.

Carter-Fenk K, Lao KU, Liu KY, Herbert JM.

J Phys Chem Lett. 2019 Jun 6;10(11):2706-2714. doi: 10.1021/acs.jpclett.9b01156. Epub 2019 May 10.

PMID:
31063380
3.

Design and synthesis of novel steroidal imidazoles as dual inhibitors of AR/CYP17 for the treatment of prostate cancer.

Hou Q, He C, Lao K, Luo G, You Q, Xiang H.

Steroids. 2019 Mar 15. pii: S0039-128X(19)30054-6. doi: 10.1016/j.steroids.2019.03.003. [Epub ahead of print]

PMID:
30885648
4.

Increasing the efficiency of CRISPR/Cas9-based gene editing by suppressing RNAi in plants.

Wang X, Lu J, Lao K, Wang S, Mo X, Xu X, Chen X, Mo B.

Sci China Life Sci. 2019 Mar 13. doi: 10.1007/s11427-019-9514-9. [Epub ahead of print] No abstract available.

PMID:
30863962
5.

Potential Astrocytic Receptors and Transporters in the Pathogenesis of Alzheimer's Disease.

Zhang X, Lao K, Qiu Z, Rahman MS, Zhang Y, Gou X.

J Alzheimers Dis. 2019;67(4):1109-1122. doi: 10.3233/JAD-181084.

PMID:
30741675
6.

Accurate molecular polarizabilities with coupled cluster theory and machine learning.

Wilkins DM, Grisafi A, Yang Y, Lao KU, DiStasio RA Jr, Ceriotti M.

Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3401-3406. doi: 10.1073/pnas.1816132116. Epub 2019 Feb 7.

PMID:
30733292
7.

Influence of Pore Size on the van der Waals Interaction in Two-Dimensional Molecules and Materials.

Yang Y, Lao KU, DiStasio RA.

Phys Rev Lett. 2019 Jan 18;122(2):026001. doi: 10.1103/PhysRevLett.122.026001.

PMID:
30720298
8.

3, 9-di-O-substituted coumestrols incorporating basic amine side chains act as novel apoptosis inducers with improved pharmacological selectivity.

Luo G, Tang Z, Li X, Hou Q, Chen Y, Lao K, Xiang H.

Bioorg Chem. 2019 Apr;85:140-151. doi: 10.1016/j.bioorg.2018.12.024. Epub 2018 Dec 22.

PMID:
30612080
9.

Aerobic exercise promotes the expression of ERCC1 to prolong lifespan: A new possible mechanism.

Ji N, Zhao W, Qian H, Yan X, Zong R, Zhang Y, Lao K.

Med Hypotheses. 2019 Jan;122:22-25. doi: 10.1016/j.mehy.2018.10.012. Epub 2018 Oct 17.

PMID:
30593415
11.

Computationally Assisted Mechanistic Investigation and Development of Pd-Catalyzed Asymmetric Suzuki-Miyaura and Negishi Cross-Coupling Reactions for Tetra-ortho-Substituted Biaryl Synthesis.

Patel ND, Sieber JD, Tcyrulnikov S, Simmons BJ, Rivalti D, Duvvuri K, Zhang Y, Gao DA, Fandrick KR, Haddad N, Lao KS, Mangunuru HPR, Biswas S, Qu B, Grinberg N, Pennino S, Lee H, Song JJ, Gupton BF, Garg NK, Kozlowski MC, Senanayake CH.

ACS Catal. 2018 Nov 2;8(11):10190-10209. doi: 10.1021/acscatal.8b02509. Epub 2018 Sep 20.

PMID:
30450265
12.

Aerobic exercise-stimulated Klotho upregulation extends life span by attenuating the excess production of reactive oxygen species in the brain and kidney.

Ji N, Luan J, Hu F, Zhao Y, Lv B, Wang W, Xia M, Zhao X, Lao K.

Exp Ther Med. 2018 Oct;16(4):3511-3517. doi: 10.3892/etm.2018.6597. Epub 2018 Aug 13.

13.

A Simple Correction for Nonadditive Dispersion within Extended Symmetry-Adapted Perturbation Theory (XSAPT).

Lao KU, Herbert JM.

J Chem Theory Comput. 2018 Oct 9;14(10):5128-5142. doi: 10.1021/acs.jctc.8b00527. Epub 2018 Sep 24.

PMID:
30199632
14.

The salient role of microRNAs in atherogenesis.

Donaldson CJ, Lao KH, Zeng L.

J Mol Cell Cardiol. 2018 Sep;122:98-113. doi: 10.1016/j.yjmcc.2018.08.004. Epub 2018 Aug 8. Review.

PMID:
30098321
15.

Unraveling substituent effects on the glass transition temperatures of biorenewable polyesters.

Yu X, Jia J, Xu S, Lao KU, Sanford MJ, Ramakrishnan RK, Nazarenko SI, Hoye TR, Coates GW, DiStasio RA Jr.

Nat Commun. 2018 Jul 23;9(1):2880. doi: 10.1038/s41467-018-05269-3.

16.

Copper-catalyzed asymmetric hydrogenation of 2-substituted ketones via dynamic kinetic resolution.

Zatolochnaya OV, Rodríguez S, Zhang Y, Lao KS, Tcyrulnikov S, Li G, Wang XJ, Qu B, Biswas S, Mangunuru HPR, Rivalti D, Sieber JD, Desrosiers JN, Leung JC, Grinberg N, Lee H, Haddad N, Yee NK, Song JJ, Kozlowski MC, Senanayake CH.

Chem Sci. 2018 Apr 23;9(19):4505-4510. doi: 10.1039/c8sc00434j. eCollection 2018 May 21.

17.

Drug development for Alzheimer's disease: review.

Lao K, Ji N, Zhang X, Qiao W, Tang Z, Gou X.

J Drug Target. 2018 Jun 20:1-10. doi: 10.1080/1061186X.2018.1474361. [Epub ahead of print]

PMID:
29732929
18.

Gpn2 and Rba50 Directly Participate in the Assembly of the Rpb3 Subcomplex in the Biogenesis of RNA Polymerase II.

Zeng F, Hua Y, Liu X, Liu S, Lao K, Zhang Z, Kong D.

Mol Cell Biol. 2018 Jun 14;38(13). pii: e00091-18. doi: 10.1128/MCB.00091-18. Print 2018 Jul 1.

19.

Atomic Orbital Implementation of Extended Symmetry-Adapted Perturbation Theory (XSAPT) and Benchmark Calculations for Large Supramolecular Complexes.

Lao KU, Herbert JM.

J Chem Theory Comput. 2018 Jun 12;14(6):2955-2978. doi: 10.1021/acs.jctc.8b00058. Epub 2018 May 2.

PMID:
29660288
20.

Coherent, atomically thin transition-metal dichalcogenide superlattices with engineered strain.

Xie S, Tu L, Han Y, Huang L, Kang K, Lao KU, Poddar P, Park C, Muller DA, DiStasio RA Jr, Park J.

Science. 2018 Mar 9;359(6380):1131-1136. doi: 10.1126/science.aao5360.

PMID:
29590041
21.

Structure-activity relationships of 2, 4-disubstituted pyrimidines as dual ERα/VEGFR-2 ligands with anti-breast cancer activity.

Luo G, Tang Z, Lao K, Li X, You Q, Xiang H.

Eur J Med Chem. 2018 Apr 25;150:783-795. doi: 10.1016/j.ejmech.2018.03.018. Epub 2018 Mar 7.

PMID:
29587221
22.

Can elevated lactate and LDH produce a false positive enzymatic ethanol result in live patients presenting to the emergency department?

Nacca N, Hodgman MJ, Lao K, Elkins M, Holland MG.

Clin Toxicol (Phila). 2018 Mar;56(3):189-192. doi: 10.1080/15563650.2017.1357825. Epub 2017 Aug 16.

PMID:
28812382
23.

Design, synthesis and biological evaluation of novel 2-methoxyestradiol analogs as dual selective estrogen receptor modulators (SERMs) and antiangiogenic agents.

Lao K, Wang Y, Chen M, Zhang J, You Q, Xiang H.

Eur J Med Chem. 2017 Oct 20;139:390-400. doi: 10.1016/j.ejmech.2017.08.016. Epub 2017 Aug 7.

PMID:
28810190
24.

Design, synthesis and biological evaluation of novel 3-oxo-4-oxa-5α-androst-17β-amide derivatives as dual 5α-reductase inhibitors and androgen receptor antagonists.

Lao K, Sun J, Wang C, Wang Y, You Q, Xiao H, Xiang H.

Bioorg Med Chem Lett. 2017 Sep 1;27(17):4212-4217. doi: 10.1016/j.bmcl.2017.05.078. Epub 2017 May 27.

PMID:
28757062
25.

Prescribing trends and indications of antipsychotic medication in Hong Kong from 2004 to 2014: General and vulnerable patient groups.

Lao KSJ, Tam AWY, Wong ICK, Besag FMC, Man KKC, Chui CSL, Chan EW.

Pharmacoepidemiol Drug Saf. 2017 Nov;26(11):1387-1394. doi: 10.1002/pds.4244. Epub 2017 Jun 30.

PMID:
28665012
26.

Design, synthesis and biological evaluation of novel androst-3,5-diene-3-carboxylic acid derivatives as inhibitors of 5α-reductase type 1 and 2.

Lao K, Sun J, Wang C, Lyu W, Zhou B, Zhao R, Xu Q, You Q, Xiang H.

Steroids. 2017 Aug;124:29-34. doi: 10.1016/j.steroids.2017.05.011. Epub 2017 May 24.

PMID:
28549802
27.

The role of nesfatin-1 expression in letrozole-induced polycystic ovaries in the rat.

Xu Y, Zhang H, Li Q, Lao K, Wang Y.

Gynecol Endocrinol. 2017 Jun;33(6):438-441. doi: 10.1080/09513590.2017.1290068. Epub 2017 Feb 21.

PMID:
28277136
29.
30.

[Hemoglobin H disease with a rare α-thalassemia gene mutation (--SEA*92A>Gα): pedigree analysis and genetic diagnosis].

Yan SH, Lao KG, Fu KP, Gong FF, Wen XJ, Zhou WJ.

Nan Fang Yi Ke Da Xue Xue Bao. 2016 Aug 20;36(9):1295-1298. Chinese.

PMID:
27687668
31.

XBP1 splicing triggers miR-150 transfer from smooth muscle cells to endothelial cells via extracellular vesicles.

Zhao Y, Li Y, Luo P, Gao Y, Yang J, Lao KH, Wang G, Cockerill G, Hu Y, Xu Q, Li T, Zeng L.

Sci Rep. 2016 Jun 24;6:28627. doi: 10.1038/srep28627.

32.

Design, synthesis and evaluation of 6-aryl-indenoisoquinolone derivatives dual targeting ERα and VEGFR-2 as anti-breast cancer agents.

Tang Z, Wu C, Wang T, Lao K, Wang Y, Liu L, Muyaba M, Xu P, He C, Luo G, Qian Z, Niu S, Wang L, Wang Y, Xiao H, You Q, Xiang H.

Eur J Med Chem. 2016 Aug 8;118:328-39. doi: 10.1016/j.ejmech.2016.04.029. Epub 2016 Apr 13.

PMID:
27176944
33.

Understanding the many-body expansion for large systems. II. Accuracy considerations.

Lao KU, Liu KY, Richard RM, Herbert JM.

J Chem Phys. 2016 Apr 28;144(16):164105. doi: 10.1063/1.4947087.

PMID:
27131529
34.

Energy Decomposition Analysis with a Stable Charge-Transfer Term for Interpreting Intermolecular Interactions.

Lao KU, Herbert JM.

J Chem Theory Comput. 2016 Jun 14;12(6):2569-82. doi: 10.1021/acs.jctc.6b00155. Epub 2016 May 6.

PMID:
27049750
35.

Medication safety research by observational study design.

Lao KS, Chui CS, Man KK, Lau WC, Chan EW, Wong IC.

Int J Clin Pharm. 2016 Jun;38(3):676-84. doi: 10.1007/s11096-016-0285-6. Epub 2016 Mar 22. Review.

36.

Management of acute agitation in Hong Kong and comparisons with Australasia.

Chan EW, Tang C, Lao KS, Ling Pong L, Tsui MS, Ho HF, Wong GC, Kong DC, McD Taylor D, Knott JC, Wong IC.

Emerg Med Australas. 2015 Dec;27(6):542-548. doi: 10.1111/1742-6723.12499. Epub 2015 Dec 3.

PMID:
26635127
37.

Accurate description of intermolecular interactions involving ions using symmetry-adapted perturbation theory.

Lao KU, Schäffer R, Jansen G, Herbert JM.

J Chem Theory Comput. 2015 Jun 9;11(6):2473-86. doi: 10.1021/ct5010593. Epub 2015 May 4.

PMID:
26575547
38.

IL-10 regulate decidual Tregs apoptosis contributing to the abnormal pregnancy with Toxoplasma gondii infection.

Lao K, Zhao M, Li Z, Liu X, Zhang H, Jiang Y, Wang Y, Hu X.

Microb Pathog. 2015 Dec;89:210-6. doi: 10.1016/j.micpath.2015.10.002. Epub 2015 Nov 2.

PMID:
26541670
39.

Diagnosis of a Family with the Novel -α(21.9) Thalassemia Deletion.

Long J, Pang W, Sun L, Lao K, Weng X, Ye X, Wu S, Song C, Wei X, Yan S.

Hemoglobin. 2015;39(6):419-22. doi: 10.3109/03630269.2015.1077142. Epub 2015 Sep 7.

PMID:
26479841
40.

Endothelial and smooth muscle cell transformation in atherosclerosis.

Lao KH, Zeng L, Xu Q.

Curr Opin Lipidol. 2015 Oct;26(5):449-56. doi: 10.1097/MOL.0000000000000219. Review.

PMID:
26218417
41.

Impact of CRFR1 Ablation on Amyloid-β Production and Accumulation in a Mouse Model of Alzheimer's Disease.

Campbell SN, Zhang C, Roe AD, Lee N, Lao KU, Monte L, Donohue MC, Rissman RA.

J Alzheimers Dis. 2015;45(4):1175-84. doi: 10.3233/JAD-142844.

42.

Symmetry-adapted perturbation theory with Kohn-Sham orbitals using non-empirically tuned, long-range-corrected density functionals.

Lao KU, Herbert JM.

J Chem Phys. 2014 Jan 28;140(4):044108. doi: 10.1063/1.4862644.

PMID:
25669506
43.

Accurate and efficient quantum chemistry calculations for noncovalent interactions in many-body systems: the XSAPT family of methods.

Lao KU, Herbert JM.

J Phys Chem A. 2015 Jan 15;119(2):235-52. doi: 10.1021/jp5098603. Epub 2014 Dec 14.

44.

miR-142 regulates the tumorigenicity of human breast cancer stem cells through the canonical WNT signaling pathway.

Isobe T, Hisamori S, Hogan DJ, Zabala M, Hendrickson DG, Dalerba P, Cai S, Scheeren F, Kuo AH, Sikandar SS, Lam JS, Qian D, Dirbas FM, Somlo G, Lao K, Brown PO, Clarke MF, Shimono Y.

Elife. 2014 Nov 18;3. doi: 10.7554/eLife.01977.

45.

Rapid detection of Down's syndrome using quantitative real-time PCR (qPCR) targeting segmental duplications on chromosomes 21 and 11.

Sun L, Fan Z, Weng X, Ye X, Long J, Fu K, Yan S, Wang B, Zhuo Y, Liu X, Lao K.

Gene. 2014 Dec 1;552(2):272-6. doi: 10.1016/j.gene.2014.09.044. Epub 2014 Sep 23.

PMID:
25256276
46.

Determination of six polyynes in Oplopanax horridus and Oplopanax elatus using polyethylene glycol modified reversed migration microemulsion electrokinetic chromatography.

Yang ZM, Zhao J, Lao KM, Chen XJ, Leong F, Wang CZ, Yuan CS, Li SP.

Electrophoresis. 2014 Oct;35(20):2959-64. doi: 10.1002/elps.201400159.

PMID:
25070635
47.

Discovery of novel aromatase inhibitors using a homogeneous time-resolved fluorescence assay.

Ji JZ, Lao KJ, Hu J, Pang T, Jiang ZZ, Yuan HL, Miao JS, Chen X, Ning SS, Xiang H, Guo YM, Yan M, Zhang LY.

Acta Pharmacol Sin. 2014 Aug;35(8):1082-92. doi: 10.1038/aps.2014.53. Epub 2014 Jul 21.

48.

Role of biomechanical forces in stem cell vascular lineage differentiation.

Potter CM, Lao KH, Zeng L, Xu Q.

Arterioscler Thromb Vasc Biol. 2014 Oct;34(10):2184-90. doi: 10.1161/ATVBAHA.114.303423. Epub 2014 Jul 10. Review.

PMID:
25012135
49.

Understanding the many-body expansion for large systems. I. Precision considerations.

Richard RM, Lao KU, Herbert JM.

J Chem Phys. 2014 Jul 7;141(1):014108. doi: 10.1063/1.4885846.

PMID:
25005278
50.

miR-409-3p/-5p promotes tumorigenesis, epithelial-to-mesenchymal transition, and bone metastasis of human prostate cancer.

Josson S, Gururajan M, Hu P, Shao C, Chu GY, Zhau HE, Liu C, Lao K, Lu CL, Lu YT, Lichterman J, Nandana S, Li Q, Rogatko A, Berel D, Posadas EM, Fazli L, Sareen D, Chung LW.

Clin Cancer Res. 2014 Sep 1;20(17):4636-46. doi: 10.1158/1078-0432.CCR-14-0305. Epub 2014 Jun 24.

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