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Immunization with full-length Plasmodium falciparum merozoite surface protein 1 is safe and elicits functional cytophilic antibodies in a randomized first-in-human trial.

Blank A, Fürle K, Jäschke A, Mikus G, Lehmann M, Hüsing J, Heiss K, Giese T, Carter D, Böhnlein E, Lanzer M, Haefeli WE, Bujard H.

NPJ Vaccines. 2020 Jan 31;5:10. doi: 10.1038/s41541-020-0160-2. eCollection 2020.


Value of SUVmax for the Prediction of Bone Invasion in Oral Squamous Cell Carcinoma.

Stalder SA, Schumann P, Lanzer M, Hüllner MW, Rupp NJ, Broglie MA, Morand GB.

Biology (Basel). 2020 Feb 2;9(2). pii: E23. doi: 10.3390/biology9020023.


Virtual planning, simultaneous dental implantation and CAD/CAM plate fixation: a paradigm change in maxillofacial reconstruction.

Seier T, Hingsammer L, Schumann P, Gander T, Rücker M, Lanzer M.

Int J Oral Maxillofac Surg. 2019 Dec 20. pii: S0901-5027(19)31408-0. doi: 10.1016/j.ijom.2019.11.010. [Epub ahead of print]


Overexpression of the HECT ubiquitin ligase PfUT prolongs the intraerythrocytic cycle and reduces invasion efficiency of Plasmodium falciparum.

Jankowska-Döllken M, Sanchez CP, Cyrklaff M, Lanzer M.

Sci Rep. 2019 Dec 4;9(1):18333. doi: 10.1038/s41598-019-54854-z.


Hemoglobin S and C affect biomechanical membrane properties of P. falciparum-infected erythrocytes.

Fröhlich B, Jäger J, Lansche C, Sanchez CP, Cyrklaff M, Buchholz B, Soubeiga ST, Simpore J, Ito H, Schwarz US, Lanzer M, Tanaka M.

Commun Biol. 2019 Aug 13;2:311. doi: 10.1038/s42003-019-0556-6. eCollection 2019.


Phosphomimetic substitution at Ser-33 of the chloroquine resistance transporter PfCRT reconstitutes drug responses in Plasmodium falciparum.

Sanchez CP, Moliner Cubel S, Nyboer B, Jankowska-Döllken M, Schaeffer-Reiss C, Ayoub D, Planelles G, Lanzer M.

J Biol Chem. 2019 Aug 23;294(34):12766-12778. doi: 10.1074/jbc.RA119.009464. Epub 2019 Jul 8.


Novel application of the Clavien-Dindo classification system and the comprehensive complications index® in microvascular free tissue transfer to the head and neck.

Ebner JJ, Mehra T, Gander T, Schumann P, Essig H, Zweifel D, Rücker M, Slankamenac K, Lanzer M.

Oral Oncol. 2019 Jul;94:21-25. doi: 10.1016/j.oraloncology.2019.05.005. Epub 2019 May 9. No abstract available.


Single-molecule imaging and quantification of the immune-variant adhesin VAR2CSA on knobs of Plasmodium falciparum-infected erythrocytes.

Sanchez CP, Karathanasis C, Sanchez R, Cyrklaff M, Jäger J, Buchholz B, Schwarz US, Heilemann M, Lanzer M.

Commun Biol. 2019 May 8;2:172. doi: 10.1038/s42003-019-0429-z. eCollection 2019.


The influence of lymph node ratio on survival and disease recurrence in squamous cell carcinoma of the tongue.

Hingsammer L, Seier T, Ikenberg J, Schumann P, Zweifel D, Rücker M, Bredell M, Lanzer M.

Int J Oral Maxillofac Surg. 2019 Jul;48(7):851-856. doi: 10.1016/j.ijom.2019.01.008. Epub 2019 Feb 7.


Precision of Simultaneous Guided Dental Implantation in Microvascular Fibular Flap Reconstructions With and Without Additional Guiding Splints.

Zweifel D, Bredell MG, Lanzer M, Rostetter C, Rücker M, Studer S.

J Oral Maxillofac Surg. 2019 May;77(5):971-976. doi: 10.1016/j.joms.2018.12.025. Epub 2018 Dec 31.


The sickle cell trait affects contact dynamics and endothelial cell activation in Plasmodium falciparum-infected erythrocytes.

Lansche C, Dasanna AK, Quadt K, Fröhlich B, Missirlis D, Tétard M, Gamain B, Buchholz B, Sanchez CP, Tanaka M, Schwarz US, Lanzer M.

Commun Biol. 2018 Nov 30;1:211. doi: 10.1038/s42003-018-0223-3. eCollection 2018.


The sickle cell trait affects contact dynamics and endothelial cell activation in Plasmodium falciparum-infected erythrocytes.

Lansche C, Dasanna AK, Quadt K, Fröhlich B, Missirlis D, Tétard M, Gamain B, Buchholz B, Sanchez CP, Tanaka M, Schwarz US, Lanzer M.

Commun Biol. 2018 Nov 30;1(1):211. doi: 10.1038/s42003-018-0223-3.


Sentinel lymph node biopsy for early stage tongue cancer-a 14-year single-centre experience.

Hingsammer L, Seier T, Zweifel D, Huber G, Rücker M, Bredell M, Lanzer M.

Int J Oral Maxillofac Surg. 2019 Apr;48(4):437-442. doi: 10.1016/j.ijom.2018.10.011. Epub 2018 Oct 30.


Complication rate in mandibular angle fractures-one vs. two plates: a 12-year retrospective analysis.

Ferrari R, Lanzer M, Wiedemeier D, Rücker M, Bredell M.

Oral Maxillofac Surg. 2018 Dec;22(4):435-441. doi: 10.1007/s10006-018-0728-4. Epub 2018 Oct 16.


Total virtual workflow in CAD-CAM bony reconstruction with a single step free fibular graft and immediate dental implants.

Zweifel D, Bredell MG, Essig H, Gander T, Lanzer M, Rostetter C, Rücker M, Studer S.

Br J Oral Maxillofac Surg. 2018 Nov;56(9):859-863. doi: 10.1016/j.bjoms.2018.09.010. Epub 2018 Oct 4.


Profiling of the anti-malarial drug candidate SC83288 against artemisinins in Plasmodium falciparum.

Duffey M, Sanchez CP, Lanzer M.

Malar J. 2018 Mar 20;17(1):121. doi: 10.1186/s12936-018-2279-4.


Retrospective analysis of 471 surgically treated zygomaticomaxillary complex fractures.

Blumer M, Kumalic S, Gander T, Lanzer M, Rostetter C, Rücker M, Lübbers HT.

J Craniomaxillofac Surg. 2018 Feb;46(2):269-273. doi: 10.1016/j.jcms.2017.11.010. Epub 2017 Nov 23.


Lensless Tomographic Imaging of Near Surface Structures of Frozen Hydrated Malaria-Infected Human Erythrocytes by Coherent X-Ray Diffraction Microscopy.

Frank V, Chushkin Y, Fröhlich B, Abuillan W, Rieger H, Becker AS, Yamamoto A, Rossetti FF, Kaufmann S, Lanzer M, Zontone F, Tanaka M.

Sci Rep. 2017 Oct 26;7(1):14081. doi: 10.1038/s41598-017-14586-4.


Iron is a substrate of the Plasmodium falciparum chloroquine resistance transporter PfCRT in Xenopus oocytes.

Bakouh N, Bellanca S, Nyboer B, Moliner Cubel S, Karim Z, Sanchez CP, Stein WD, Planelles G, Lanzer M.

J Biol Chem. 2017 Sep 29;292(39):16109-16121. doi: 10.1074/jbc.M117.805200. Epub 2017 Aug 2.


Knockout of the peroxiredoxin 5 homologue PFAOP does not affect the artemisinin susceptibility of Plasmodium falciparum.

Djuika CF, Staudacher V, Sanchez CP, Lanzer M, Deponte M.

Sci Rep. 2017 Jun 30;7(1):4410. doi: 10.1038/s41598-017-04277-5.


Rolling Adhesion of Schizont Stage Malaria-Infected Red Blood Cells in Shear Flow.

Dasanna AK, Lansche C, Lanzer M, Schwarz US.

Biophys J. 2017 May 9;112(9):1908-1919. doi: 10.1016/j.bpj.2017.04.001.


Erratum: SC83288 is a clinical development candidate for the treatment of severe malaria.

Pegoraro S, Duffey M, Otto TD, Wang Y, Rösemann R, Baumgartner R, Fehler SK, Lucantoni L, Avery VM, Moreno-Sabater A, Mazier D, Vial HJ, Strobl S, Sanchez CP, Lanzer M.

Nat Commun. 2017 Apr 6;8:15273. doi: 10.1038/ncomms15273. No abstract available.


A Redox-Active Fluorescent pH Indicator for Detecting Plasmodium falciparum Strains with Reduced Responsiveness to Quinoline Antimalarial Drugs.

Jida M, Sanchez CP, Urgin K, Ehrhardt K, Mounien S, Geyer A, Elhabiri M, Lanzer M, Davioud-Charvet E.

ACS Infect Dis. 2017 Feb 10;3(2):119-131. doi: 10.1021/acsinfecdis.5b00141. Epub 2016 Dec 7.


SC83288 is a clinical development candidate for the treatment of severe malaria.

Pegoraro S, Duffey M, Otto TD, Wang Y, Rösemann R, Baumgartner R, Fehler SK, Lucantoni L, Avery VM, Moreno-Sabater A, Mazier D, Vial HJ, Strobl S, Sanchez CP, Lanzer M.

Nat Commun. 2017 Jan 31;8:14193. doi: 10.1038/ncomms14193.


Pharmacomodulation of the Antimalarial Plasmodione: Synthesis of Biaryl- and N-Arylalkylamine Analogues, Antimalarial Activities and Physicochemical Properties.

Urgin K, Jida M, Ehrhardt K, Müller T, Lanzer M, Maes L, Elhabiri M, Davioud-Charvet E.

Molecules. 2017 Jan 19;22(1). pii: E161. doi: 10.3390/molecules22010161.


Oxidative insult can induce malaria-protective trait of sickle and fetal erythrocytes.

Cyrklaff M, Srismith S, Nyboer B, Burda K, Hoffmann A, Lasitschka F, Adjalley S, Bisseye C, Simpore J, Mueller AK, Sanchez CP, Frischknecht F, Lanzer M.

Nat Commun. 2016 Nov 8;7:13401. doi: 10.1038/ncomms13401.


Trafficking of the exported P. falciparum chaperone PfHsp70x.

Rhiel M, Bittl V, Tribensky A, Charnaud SC, Strecker M, Müller S, Lanzer M, Sanchez C, Schaeffer-Reiss C, Westermann B, Crabb BS, Gilson PR, Külzer S, Przyborski JM.

Sci Rep. 2016 Nov 8;6:36174. doi: 10.1038/srep36174.


Incidence and frequency of nondental incidental findings on cone-beam computed tomography.

Togan B, Gander T, Lanzer M, Martin R, Lübbers HT.

J Craniomaxillofac Surg. 2016 Sep;44(9):1373-80. doi: 10.1016/j.jcms.2016.06.026. Epub 2016 Jul 5.


Differential time-dependent volumetric and surface area changes and delayed induction of new permeation pathways in P. falciparum-infected hemoglobinopathic erythrocytes.

Waldecker M, Dasanna AK, Lansche C, Linke M, Srismith S, Cyrklaff M, Sanchez CP, Schwarz US, Lanzer M.

Cell Microbiol. 2017 Feb;19(2). doi: 10.1111/cmi.12650. Epub 2016 Aug 25.


The Effects of Preoperative Radiotherapy on Head and Neck Free Flap Anastomosis Success.

Rostetter C, Kuster IM, Schenkel JS, Lanzer M, Gander T, Kruse AL.

J Oral Maxillofac Surg. 2016 Dec;74(12):2521-2525. doi: 10.1016/j.joms.2016.05.020. Epub 2016 May 26.


The Redox Cycler Plasmodione Is a Fast-Acting Antimalarial Lead Compound with Pronounced Activity against Sexual and Early Asexual Blood-Stage Parasites.

Ehrhardt K, Deregnaucourt C, Goetz AA, Tzanova T, Gallo V, Arese P, Pradines B, Adjalley SH, Bagrel D, Blandin S, Lanzer M, Davioud-Charvet E.

Antimicrob Agents Chemother. 2016 Aug 22;60(9):5146-58. doi: 10.1128/AAC.02975-15. Print 2016 Sep.


Ticket to ride: export of proteins to the Plasmodium falciparum-infected erythrocyte.

Przyborski JM, Nyboer B, Lanzer M.

Mol Microbiol. 2016 Jul;101(1):1-11. doi: 10.1111/mmi.13380. Epub 2016 May 23. Review.


Modeling cytoadhesion of Plasmodium falciparum-infected erythrocytes and leukocytes-common principles and distinctive features.

Helms G, Dasanna AK, Schwarz US, Lanzer M.

FEBS Lett. 2016 Jul;590(13):1955-71. doi: 10.1002/1873-3468.12142. Epub 2016 Apr 5. Review.


Scapular Free Vascularised Bone Flaps for Mandibular Reconstruction: Are Dental Implants Possible?

Lanzer M, Gander T, Grätz K, Rostetter C, Zweifel D, Bredell M.

J Oral Maxillofac Res. 2015 Jun 30;6(3):e4. doi: 10.5037/jomr.2015.6304. eCollection 2015 Jul-Sep.


The 3dMD photogrammetric photo system in cranio-maxillofacial surgery: Validation of interexaminer variations and perceptions.

Nord F, Ferjencik R, Seifert B, Lanzer M, Gander T, Matthews F, Rücker M, Lübbers HT.

J Craniomaxillofac Surg. 2015 Nov;43(9):1798-803. doi: 10.1016/j.jcms.2015.08.017. Epub 2015 Aug 29.


Closed versus open treatment of mandibular condylar process fractures: A meta-analysis of retrospective and prospective studies.

Berner T, Essig H, Schumann P, Blumer M, Lanzer M, Rücker M, Gander T.

J Craniomaxillofac Surg. 2015 Oct;43(8):1404-8. doi: 10.1016/j.jcms.2015.07.027. Epub 2015 Aug 4. Review.


Decelerated vascularization in tissue-engineered constructs in association with diabetes mellitus in vivo.

Schumann P, Lindhorst D, Kampmann A, Gellrich NC, Krone-Wolf S, Meyer-Lindenberg A, von See C, Gander T, Lanzer M, Rücker M, Essig H.

J Diabetes Complications. 2015 Sep-Oct;29(7):855-64. doi: 10.1016/j.jdiacomp.2015.06.004. Epub 2015 Jun 16.


Pâte adhésive bucco-dentaire Solcoseryl ® – mécanisme d’action et risques.

Yildirim A, Metzler P, Lanzer M, Lübbers HT, Yildirim V.

Swiss Dent J. 2015;125(6):740-1. French.


Solcoseryl® Dental-Adhäsivpaste - Wirkmechanismus und Risiken.

Yildirim A, Metzler P, Lanzer M, Lübbers HT, Yildirim V.

Swiss Dent J. 2015;125(5):612-3. German.


Anatomic (positional) variation of maxillary wisdom teeth with special regard to the maxillary sinus.

Lanzer M, Pejicic R, Kruse AL, Schneider T, Grätz KW, Lübbers HT.

Swiss Dent J. 2015;125(5):555-71. English, German.


[CEOT - Calcified anomalies in dental X-ray. A case-based review of differential diagnoses in radiopaque lesions in maxilla and mandible].

Lanzer M, Yildirim A, Kruse AL, Grätz K, Lübbers HT.

Swiss Dent J. 2015;125(3):315-27. Review. French, German.


Plasmodium falciparum antioxidant protein reveals a novel mechanism for balancing turnover and inactivation of peroxiredoxins.

Staudacher V, Djuika CF, Koduka J, Schlossarek S, Kopp J, Büchler M, Lanzer M, Deponte M.

Free Radic Biol Med. 2015 Aug;85:228-36. doi: 10.1016/j.freeradbiomed.2015.04.030. Epub 2015 May 5.


Balancing drug resistance and growth rates via compensatory mutations in the Plasmodium falciparum chloroquine resistance transporter.

Petersen I, Gabryszewski SJ, Johnston GL, Dhingra SK, Ecker A, Lewis RE, de Almeida MJ, Straimer J, Henrich PP, Palatulan E, Johnson DJ, Coburn-Flynn O, Sanchez C, Lehane AM, Lanzer M, Fidock DA.

Mol Microbiol. 2015 Jul;97(2):381-95. doi: 10.1111/mmi.13035. Epub 2015 May 20.


Unknown primary of the head and neck: A long-term follow-up.

Lanzer M, Bachna-Rotter S, Graupp M, Bredell M, Rücker M, Huber G, Reinisch S, Schumann P.

J Craniomaxillofac Surg. 2015 May;43(4):574-9. doi: 10.1016/j.jcms.2015.03.004. Epub 2015 Mar 9.


Hemoglobin S and C affect protein export in Plasmodium falciparum-infected erythrocytes.

Kilian N, Srismith S, Dittmer M, Ouermi D, Bisseye C, Simpore J, Cyrklaff M, Sanchez CP, Lanzer M.

Biol Open. 2015 Feb 20;4(3):400-10. doi: 10.1242/bio.201410942.


Lokalanästhetika - Wirkmechanismus und Risikendesalter.

Gander T, Kruse AL, Lanzer M, Lübbers HT.

Swiss Dent J. 2015;125(1):44-7. French, German.


Prokaryotic ancestry and gene fusion of a dual localized peroxiredoxin in malaria parasites.

Djuika CF, Huerta-Cepas J, Przyborski JM, Deil S, Sanchez CP, Doerks T, Bork P, Lanzer M, Deponte M.

Microb Cell. 2015 Jan 5;2(1):5-13. doi: 10.15698/mic2015.01.182.


Multiple drugs compete for transport via the Plasmodium falciparum chloroquine resistance transporter at distinct but interdependent sites.

Bellanca S, Summers RL, Meyrath M, Dave A, Nash MN, Dittmer M, Sanchez CP, Stein WD, Martin RE, Lanzer M.

J Biol Chem. 2014 Dec 26;289(52):36336-51. doi: 10.1074/jbc.M114.614206. Epub 2014 Nov 6.


Cytoadhesion of Plasmodium falciparum-infected erythrocytes to chondroitin-4-sulfate is cooperative and shear enhanced.

Rieger H, Yoshikawa HY, Quadt K, Nielsen MA, Sanchez CP, Salanti A, Tanaka M, Lanzer M.

Blood. 2015 Jan 8;125(2):383-91. doi: 10.1182/blood-2014-03-561019. Epub 2014 Oct 28.


Export of virulence proteins by malaria-infected erythrocytes involves remodeling of host actin cytoskeleton.

Rug M, Cyrklaff M, Mikkonen A, Lemgruber L, Kuelzer S, Sanchez CP, Thompson J, Hanssen E, O'Neill M, Langer C, Lanzer M, Frischknecht F, Maier AG, Cowman AF.

Blood. 2014 Nov 27;124(23):3459-68. doi: 10.1182/blood-2014-06-583054. Epub 2014 Aug 19.

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