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Items: 44

1.

Structure-Activity Relationships, Pharmacokinetics, and Pharmacodynamics of the Kir6.2/SUR1-Specific Channel Opener VU0071063.

Kharade SV, Sanchez-Andres JV, Fulton MG, Shelton EL, Blobaum AL, Engers DW, Hofmann CS, Dadi PK, Lantier L, Jacobson DA, Lindsley CW, Denton JS.

J Pharmacol Exp Ther. 2019 Sep;370(3):350-359. doi: 10.1124/jpet.119.257204. Epub 2019 Jun 14.

PMID:
31201216
2.

Energy metabolism couples hepatocyte integrin-linked kinase to liver glucoregulation and postabsorptive responses of mice in an age-dependent manner.

Trefts E, Hughey CC, Lantier L, Lark DS, Boyd KL, Pozzi A, Zent R, Wasserman DH.

Am J Physiol Endocrinol Metab. 2019 Jun 1;316(6):E1118-E1135. doi: 10.1152/ajpendo.00496.2018. Epub 2019 Mar 5.

PMID:
30835508
3.

Adiposity-Independent Effects of Aging on Insulin Sensitivity and Clearance in Mice and Humans.

Ehrhardt N, Cui J, Dagdeviren S, Saengnipanthkul S, Goodridge HS, Kim JK, Lantier L, Guo X, Chen YI, Raffel LJ, Buchanan TA, Hsueh WA, Rotter JI, Goodarzi MO, Péterfy M.

Obesity (Silver Spring). 2019 Mar;27(3):434-443. doi: 10.1002/oby.22418.

PMID:
30801985
4.

SIRT2 knockout exacerbates insulin resistance in high fat-fed mice.

Lantier L, Williams AS, Hughey CC, Bracy DP, James FD, Ansari MA, Gius D, Wasserman DH.

PLoS One. 2018 Dec 11;13(12):e0208634. doi: 10.1371/journal.pone.0208634. eCollection 2018.

5.

Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase.

Hunter RW, Hughey CC, Lantier L, Sundelin EI, Peggie M, Zeqiraj E, Sicheri F, Jessen N, Wasserman DH, Sakamoto K.

Nat Med. 2018 Sep;24(9):1395-1406. doi: 10.1038/s41591-018-0159-7. Epub 2018 Aug 27.

6.

CalR: A Web-Based Analysis Tool for Indirect Calorimetry Experiments.

Mina AI, LeClair RA, LeClair KB, Cohen DE, Lantier L, Banks AS.

Cell Metab. 2018 Oct 2;28(4):656-666.e1. doi: 10.1016/j.cmet.2018.06.019. Epub 2018 Jul 12.

PMID:
30017358
7.

Caspase-11-dependent pyroptosis of lung epithelial cells protects from melioidosis while caspase-1 mediates macrophage pyroptosis and production of IL-18.

Wang J, Sahoo M, Lantier L, Warawa J, Cordero H, Deobald K, Re F.

PLoS Pathog. 2018 May 23;14(5):e1007105. doi: 10.1371/journal.ppat.1007105. eCollection 2018 May.

8.

Reduced Nonexercise Activity Attenuates Negative Energy Balance in Mice Engaged in Voluntary Exercise.

Lark DS, Kwan JR, McClatchey PM, James MN, James FD, Lighton JRB, Lantier L, Wasserman DH.

Diabetes. 2018 May;67(5):831-840. doi: 10.2337/db17-1293. Epub 2018 Mar 6.

9.

AMPK in skeletal muscle function and metabolism.

Kjøbsted R, Hingst JR, Fentz J, Foretz M, Sanz MN, Pehmøller C, Shum M, Marette A, Mounier R, Treebak JT, Wojtaszewski JFP, Viollet B, Lantier L.

FASEB J. 2018 Apr;32(4):1741-1777. doi: 10.1096/fj.201700442R. Epub 2018 Jan 5. Review.

10.

High salt intake reprioritizes osmolyte and energy metabolism for body fluid conservation.

Kitada K, Daub S, Zhang Y, Klein JD, Nakano D, Pedchenko T, Lantier L, LaRocque LM, Marton A, Neubert P, Schröder A, Rakova N, Jantsch J, Dikalova AE, Dikalov SI, Harrison DG, Müller DN, Nishiyama A, Rauh M, Harris RC, Luft FC, Wassermann DH, Sands JM, Titze J.

J Clin Invest. 2017 May 1;127(5):1944-1959. doi: 10.1172/JCI88532. Epub 2017 Apr 17.

11.

Cytochrome P450 epoxygenase-derived epoxyeicosatrienoic acids contribute to insulin sensitivity in mice and in humans.

Gangadhariah MH, Dieckmann BW, Lantier L, Kang L, Wasserman DH, Chiusa M, Caskey CF, Dickerson J, Luo P, Gamboa JL, Capdevila JH, Imig JD, Yu C, Pozzi A, Luther JM.

Diabetologia. 2017 Jun;60(6):1066-1075. doi: 10.1007/s00125-017-4260-0. Epub 2017 Mar 28.

12.

Integrin-Linked Kinase Is Necessary for the Development of Diet-Induced Hepatic Insulin Resistance.

Williams AS, Trefts E, Lantier L, Grueter CA, Bracy DP, James FD, Pozzi A, Zent R, Wasserman DH.

Diabetes. 2017 Feb;66(2):325-334. doi: 10.2337/db16-0484. Epub 2016 Nov 29.

13.

Role of Canonical and Non-canonical Inflammasomes During Burkholderia Infection.

Sahoo M, Lantier L, Re F.

Curr Top Microbiol Immunol. 2016;397:199-214. doi: 10.1007/978-3-319-41171-2_10. Review.

PMID:
27460811
14.

IRF3 promotes adipose inflammation and insulin resistance and represses browning.

Kumari M, Wang X, Lantier L, Lyubetskaya A, Eguchi J, Kang S, Tenen D, Roh HC, Kong X, Kazak L, Ahmad R, Rosen ED.

J Clin Invest. 2016 Aug 1;126(8):2839-54. doi: 10.1172/JCI86080. Epub 2016 Jul 11.

15.

Central injection of fibroblast growth factor 1 induces sustained remission of diabetic hyperglycemia in rodents.

Scarlett JM, Rojas JM, Matsen ME, Kaiyala KJ, Stefanovski D, Bergman RN, Nguyen HT, Dorfman MD, Lantier L, Wasserman DH, Mirzadeh Z, Unterman TG, Morton GJ, Schwartz MW.

Nat Med. 2016 Jul;22(7):800-6. doi: 10.1038/nm.4101. Epub 2016 May 23.

16.

CETP Expression Protects Female Mice from Obesity-Induced Decline in Exercise Capacity.

Cappel DA, Lantier L, Palmisano BT, Wasserman DH, Stafford JM.

PLoS One. 2015 Aug 27;10(8):e0136915. doi: 10.1371/journal.pone.0136915. eCollection 2015.

17.

Tissue inflammation and nitric oxide-mediated alterations in cardiovascular function are major determinants of endotoxin-induced insulin resistance.

House LM 2nd, Morris RT, Barnes TM, Lantier L, Cyphert TJ, McGuinness OP, Otero YF.

Cardiovasc Diabetol. 2015 May 20;14:56. doi: 10.1186/s12933-015-0223-2.

18.

SIRT3 Is Crucial for Maintaining Skeletal Muscle Insulin Action and Protects Against Severe Insulin Resistance in High-Fat-Fed Mice.

Lantier L, Williams AS, Williams IM, Yang KK, Bracy DP, Goelzer M, James FD, Gius D, Wasserman DH.

Diabetes. 2015 Sep;64(9):3081-92. doi: 10.2337/db14-1810. Epub 2015 May 6.

19.

Expanding roles for AMPK in skeletal muscle plasticity.

Mounier R, Théret M, Lantier L, Foretz M, Viollet B.

Trends Endocrinol Metab. 2015 Jun;26(6):275-86. doi: 10.1016/j.tem.2015.02.009. Epub 2015 Mar 26. Review.

20.

Production of anti-LPS IgM by B1a B cells depends on IL-1β and is protective against lung infection with Francisella tularensis LVS.

del Barrio L, Sahoo M, Lantier L, Reynolds JM, Ceballos-Olvera I, Re F.

PLoS Pathog. 2015 Mar 13;11(3):e1004706. doi: 10.1371/journal.ppat.1004706. eCollection 2015 Mar.

21.

Prior AICAR stimulation increases insulin sensitivity in mouse skeletal muscle in an AMPK-dependent manner.

Kjøbsted R, Treebak JT, Fentz J, Lantier L, Viollet B, Birk JB, Schjerling P, Björnholm M, Zierath JR, Wojtaszewski JF.

Diabetes. 2015 Jun;64(6):2042-55. doi: 10.2337/db14-1402. Epub 2014 Dec 31.

22.

Approach to assessing determinants of glucose homeostasis in the conscious mouse.

Hughey CC, Wasserman DH, Lee-Young RS, Lantier L.

Mamm Genome. 2014 Oct;25(9-10):522-38. doi: 10.1007/s00335-014-9533-z. Epub 2014 Jul 30. Review.

23.

The gut flora is required for the control of intestinal infection by poly(I:C) administration in neonates.

Lacroix-Lamandé S, Guesdon W, Drouet F, Potiron L, Lantier L, Laurent F.

Gut Microbes. 2014 Jul 1;5(4):533-40. doi: 10.4161/gmic.29154. Epub 2014 Jun 11. Review.

PMID:
24918602
24.

A small-molecule benzimidazole derivative that potently activates AMPK to increase glucose transport in skeletal muscle: comparison with effects of contraction and other AMPK activators.

Lai YC, Kviklyte S, Vertommen D, Lantier L, Foretz M, Viollet B, Hallén S, Rider MH.

Biochem J. 2014 Jun 15;460(3):363-75. doi: 10.1042/BJ20131673.

PMID:
24665903
25.

AMPK controls exercise endurance, mitochondrial oxidative capacity, and skeletal muscle integrity.

Lantier L, Fentz J, Mounier R, Leclerc J, Treebak JT, Pehmøller C, Sanz N, Sakakibara I, Saint-Amand E, Rimbaud S, Maire P, Marette A, Ventura-Clapier R, Ferry A, Wojtaszewski JF, Foretz M, Viollet B.

FASEB J. 2014 Jul;28(7):3211-24. doi: 10.1096/fj.14-250449. Epub 2014 Mar 20.

PMID:
24652947
26.

Intestinal CD103+ dendritic cells are key players in the innate immune control of Cryptosporidium parvum infection in neonatal mice.

Lantier L, Lacroix-Lamandé S, Potiron L, Metton C, Drouet F, Guesdon W, Gnahoui-David A, Le Vern Y, Deriaud E, Fenis A, Rabot S, Descamps A, Werts C, Laurent F.

PLoS Pathog. 2013;9(12):e1003801. doi: 10.1371/journal.ppat.1003801. Epub 2013 Dec 19.

27.

Poly(I:C)-induced protection of neonatal mice against intestinal Cryptosporidium parvum infection requires an additional TLR5 signal provided by the gut flora.

Lantier L, Drouet F, Guesdon W, Mancassola R, Metton C, Lo-Man R, Werts C, Laurent F, Lacroix-Lamandé S.

J Infect Dis. 2014 Feb 1;209(3):457-67. doi: 10.1093/infdis/jit432. Epub 2013 Sep 6.

PMID:
24014881
28.

Glucose-6-phosphate-mediated activation of liver glycogen synthase plays a key role in hepatic glycogen synthesis.

von Wilamowitz-Moellendorff A, Hunter RW, García-Rocha M, Kang L, López-Soldado I, Lantier L, Patel K, Peggie MW, Martínez-Pons C, Voss M, Calbó J, Cohen PT, Wasserman DH, Guinovart JJ, Sakamoto K.

Diabetes. 2013 Dec;62(12):4070-82. doi: 10.2337/db13-0880. Epub 2013 Aug 29.

29.

Phosphatidylinositol 3-phosphate 5-kinase (PIKfyve) is an AMPK target participating in contraction-stimulated glucose uptake in skeletal muscle.

Liu Y, Lai YC, Hill EV, Tyteca D, Carpentier S, Ingvaldsen A, Vertommen D, Lantier L, Foretz M, Dequiedt F, Courtoy PJ, Erneux C, Viollet B, Shepherd PR, Tavaré JM, Jensen J, Rider MH.

Biochem J. 2013 Oct 15;455(2):195-206. doi: 10.1042/BJ20130644.

PMID:
23905686
30.

Relaxin treatment reverses insulin resistance in mice fed a high-fat diet.

Bonner JS, Lantier L, Hocking KM, Kang L, Owolabi M, James FD, Bracy DP, Brophy CM, Wasserman DH.

Diabetes. 2013 Sep;62(9):3251-60. doi: 10.2337/db13-0033. Epub 2013 Jun 25.

31.

Hyaluronan accumulates with high-fat feeding and contributes to insulin resistance.

Kang L, Lantier L, Kennedy A, Bonner JS, Mayes WH, Bracy DP, Bookbinder LH, Hasty AH, Thompson CB, Wasserman DH.

Diabetes. 2013 Jun;62(6):1888-96. doi: 10.2337/db12-1502. Epub 2013 Jan 24.

32.

Muscle-specific vascular endothelial growth factor deletion induces muscle capillary rarefaction creating muscle insulin resistance.

Bonner JS, Lantier L, Hasenour CM, James FD, Bracy DP, Wasserman DH.

Diabetes. 2013 Feb;62(2):572-80. doi: 10.2337/db12-0354. Epub 2012 Sep 21.

33.

Defining the contribution of AMP-activated protein kinase (AMPK) and protein kinase C (PKC) in regulation of glucose uptake by metformin in skeletal muscle cells.

Turban S, Stretton C, Drouin O, Green CJ, Watson ML, Gray A, Ross F, Lantier L, Viollet B, Hardie DG, Marette A, Hundal HS.

J Biol Chem. 2012 Jun 8;287(24):20088-99. doi: 10.1074/jbc.M111.330746. Epub 2012 Apr 17.

34.

Increased FAT/CD36 cycling and lipid accumulation in myotubes derived from obese type 2 diabetic patients.

Aguer C, Foretz M, Lantier L, Hebrard S, Viollet B, Mercier J, Kitzmann M.

PLoS One. 2011;6(12):e28981. doi: 10.1371/journal.pone.0028981. Epub 2011 Dec 16.

35.

Antagonistic control of muscle cell size by AMPK and mTORC1.

Mounier R, Lantier L, Leclerc J, Sotiropoulos A, Foretz M, Viollet B.

Cell Cycle. 2011 Aug 15;10(16):2640-6. Epub 2011 Aug 15.

PMID:
21799304
36.

Abnormal metabolism flexibility in response to high palmitate concentrations in myotubes derived from obese type 2 diabetic patients.

Kitzmann M, Lantier L, Hébrard S, Mercier J, Foretz M, Aguer C.

Biochim Biophys Acta. 2011 Apr;1812(4):423-30. doi: 10.1016/j.bbadis.2010.12.007. Epub 2010 Dec 21.

37.

AMPK inhibition in health and disease.

Viollet B, Horman S, Leclerc J, Lantier L, Foretz M, Billaud M, Giri S, Andreelli F.

Crit Rev Biochem Mol Biol. 2010 Aug;45(4):276-95. doi: 10.3109/10409238.2010.488215. Review.

38.

Coordinated maintenance of muscle cell size control by AMP-activated protein kinase.

Lantier L, Mounier R, Leclerc J, Pende M, Foretz M, Viollet B.

FASEB J. 2010 Sep;24(9):3555-61. doi: 10.1096/fj.10-155994. Epub 2010 May 11.

39.

Intramyocellular lipid accumulation is associated with permanent relocation ex vivo and in vitro of fatty acid translocase (FAT)/CD36 in obese patients.

Aguer C, Mercier J, Man CY, Metz L, Bordenave S, Lambert K, Jean E, Lantier L, Bounoua L, Brun JF, Raynaud de Mauverger E, Andreelli F, Foretz M, Kitzmann M.

Diabetologia. 2010 Jun;53(6):1151-63. doi: 10.1007/s00125-010-1708-x. Epub 2010 Mar 25.

PMID:
20333349
40.

AMP-activated protein kinase activator A-769662 is an inhibitor of the Na(+)-K(+)-ATPase.

Benziane B, Björnholm M, Lantier L, Viollet B, Zierath JR, Chibalin AV.

Am J Physiol Cell Physiol. 2009 Dec;297(6):C1554-66. doi: 10.1152/ajpcell.00010.2009. Epub 2009 Oct 14.

41.

Targeting the AMPK pathway for the treatment of Type 2 diabetes.

Viollet B, Lantier L, Devin-Leclerc J, Hebrard S, Amouyal C, Mounier R, Foretz M, Andreelli F.

Front Biosci (Landmark Ed). 2009 Jan 1;14:3380-400. Review.

42.

AMPK: Lessons from transgenic and knockout animals.

Viollet B, Athea Y, Mounier R, Guigas B, Zarrinpashneh E, Horman S, Lantier L, Hebrard S, Devin-Leclerc J, Beauloye C, Foretz M, Andreelli F, Ventura-Clapier R, Bertrand L.

Front Biosci (Landmark Ed). 2009 Jan 1;14:19-44. Review.

43.

AMP-activated protein kinase in the regulation of hepatic energy metabolism: from physiology to therapeutic perspectives.

Viollet B, Guigas B, Leclerc J, Hébrard S, Lantier L, Mounier R, Andreelli F, Foretz M.

Acta Physiol (Oxf). 2009 May;196(1):81-98. doi: 10.1111/j.1748-1716.2009.01970.x. Epub 2009 Feb 19. Review.

44.

Important role for AMPKalpha1 in limiting skeletal muscle cell hypertrophy.

Mounier R, Lantier L, Leclerc J, Sotiropoulos A, Pende M, Daegelen D, Sakamoto K, Foretz M, Viollet B.

FASEB J. 2009 Jul;23(7):2264-73. doi: 10.1096/fj.08-119057. Epub 2009 Feb 23.

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