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Items: 1 to 50 of 103

1.

Role of G-proteins and phosphorylation in the distribution of AGS3 to cell puncta.

Vural A, Fadillioglu E, Kelesoglu F, Ma D, Lanier SM.

J Cell Sci. 2018 Dec 5;131(23). pii: jcs216507. doi: 10.1242/jcs.216507.

2.

Direct Coupling of a Seven-Transmembrane-Span Receptor to a Gαi G-Protein Regulatory Motif Complex.

Robichaux WG 3rd, Oner SS, Lanier SM, Blumer JB.

Mol Pharmacol. 2015 Aug;88(2):231-7. doi: 10.1124/mol.115.097741. Epub 2015 May 13.

3.

Defective chemokine signal integration in leukocytes lacking activator of G protein signaling 3 (AGS3).

Branham-O'Connor M, Robichaux WG 3rd, Zhang XK, Cho H, Kehrl JH, Lanier SM, Blumer JB.

J Biol Chem. 2014 Apr 11;289(15):10738-47. doi: 10.1074/jbc.M113.515031. Epub 2014 Feb 26.

4.

Activators of G protein signaling exhibit broad functionality and define a distinct core signaling triad.

Blumer JB, Lanier SM.

Mol Pharmacol. 2014 Mar;85(3):388-96. doi: 10.1124/mol.113.090068. Epub 2013 Dec 3. Review.

5.

Translocation of activator of G-protein signaling 3 to the Golgi apparatus in response to receptor activation and its effect on the trans-Golgi network.

Oner SS, Vural A, Lanier SM.

J Biol Chem. 2013 Aug 16;288(33):24091-103. doi: 10.1074/jbc.M112.444505. Epub 2013 Jun 14.

6.

Group II activators of G-protein signaling: monitoring the interaction of Gα with the G-protein regulatory motif in the intact cell.

Oner SS, Blumer JB, Lanier SM.

Methods Enzymol. 2013;522:153-67. doi: 10.1016/B978-0-12-407865-9.00009-1.

PMID:
23374185
7.

Regulation of the G-protein regulatory-Gαi signaling complex by nonreceptor guanine nucleotide exchange factors.

Oner SS, Maher EM, Gabay M, Tall GG, Blumer JB, Lanier SM.

J Biol Chem. 2013 Feb 1;288(5):3003-15. doi: 10.1074/jbc.M112.418467. Epub 2012 Dec 4.

8.

Influence of the accessory protein SET on M3 muscarinic receptor phosphorylation and G protein coupling.

Simon V, Oner SS, Cohen-Tannoudji J, Tobin AB, Lanier SM.

Mol Pharmacol. 2012 Jul;82(1):17-26. doi: 10.1124/mol.111.075523. Epub 2012 Mar 30.

9.

Group II activators of G-protein signalling and proteins containing a G-protein regulatory motif.

Blumer JB, Oner SS, Lanier SM.

Acta Physiol (Oxf). 2012 Feb;204(2):202-18. doi: 10.1111/j.1748-1716.2011.02327.x. Epub 2011 Jul 5. Review.

PMID:
21615707
10.

Identification of transcription factor E3 (TFE3) as a receptor-independent activator of Gα16: gene regulation by nuclear Gα subunit and its activator.

Sato M, Hiraoka M, Suzuki H, Bai Y, Kurotani R, Yokoyama U, Okumura S, Cismowski MJ, Lanier SM, Ishikawa Y.

J Biol Chem. 2011 May 20;286(20):17766-76. doi: 10.1074/jbc.M111.219816. Epub 2011 Mar 24.

11.

Loss of activator of G-protein signaling 3 impairs renal tubular regeneration following acute kidney injury in rodents.

Regner KR, Nozu K, Lanier SM, Blumer JB, Avner ED, Sweeney WE Jr, Park F.

FASEB J. 2011 Jun;25(6):1844-55. doi: 10.1096/fj.10-169797. Epub 2011 Feb 22.

12.

Purification of heterotrimeric G protein alpha subunits by GST-Ric-8 association: primary characterization of purified G alpha(olf).

Chan P, Gabay M, Wright FA, Kan W, Oner SS, Lanier SM, Smrcka AV, Blumer JB, Tall GG.

J Biol Chem. 2011 Jan 28;286(4):2625-35. doi: 10.1074/jbc.M110.178897. Epub 2010 Nov 29.

13.

Regulation of the AGS3·G{alpha}i signaling complex by a seven-transmembrane span receptor.

Oner SS, An N, Vural A, Breton B, Bouvier M, Blumer JB, Lanier SM.

J Biol Chem. 2010 Oct 29;285(44):33949-58. doi: 10.1074/jbc.M110.138073. Epub 2010 Aug 17.

14.

Activator of G protein signaling 3 promotes epithelial cell proliferation in PKD.

Nadella R, Blumer JB, Jia G, Kwon M, Akbulut T, Qian F, Sedlic F, Wakatsuki T, Sweeney WE Jr, Wilson PD, Lanier SM, Park F.

J Am Soc Nephrol. 2010 Aug;21(8):1275-80. doi: 10.1681/ASN.2009121224. Epub 2010 May 20.

16.

Activator of G protein signaling 8 (AGS8) is required for hypoxia-induced apoptosis of cardiomyocytes: role of G betagamma and connexin 43 (CX43).

Sato M, Jiao Q, Honda T, Kurotani R, Toyota E, Okumura S, Takeya T, Minamisawa S, Lanier SM, Ishikawa Y.

J Biol Chem. 2009 Nov 6;284(45):31431-40. doi: 10.1074/jbc.M109.014068. Epub 2009 Sep 1.

17.

The PDZ and band 4.1 containing protein Frmpd1 regulates the subcellular location of activator of G-protein signaling 3 and its interaction with G-proteins.

An N, Blumer JB, Bernard ML, Lanier SM.

J Biol Chem. 2008 Sep 5;283(36):24718-28. doi: 10.1074/jbc.M803497200. Epub 2008 Jun 19.

18.

Activator of G protein signaling 3 null mice: I. Unexpected alterations in metabolic and cardiovascular function.

Blumer JB, Lord K, Saunders TL, Pacchioni A, Black C, Lazartigues E, Varner KJ, Gettys TW, Lanier SM.

Endocrinology. 2008 Aug;149(8):3842-9. doi: 10.1210/en.2008-0050. Epub 2008 May 1.

19.
20.

Mechanistic pathways and biological roles for receptor-independent activators of G-protein signaling.

Blumer JB, Smrcka AV, Lanier SM.

Pharmacol Ther. 2007 Mar;113(3):488-506. Epub 2006 Nov 28. Review.

21.

The proto-oncogene SET interacts with muscarinic receptors and attenuates receptor signaling.

Simon V, Guidry J, Gettys TW, Tobin AB, Lanier SM.

J Biol Chem. 2006 Dec 29;281(52):40310-20. Epub 2006 Oct 25.

23.

Identification and characterization of a G-protein regulatory motif in WAVE1.

Song KS, Peterson YK, Freidman A, Blumer JB, Sato M, Lanier SM.

FEBS Lett. 2006 Apr 3;580(8):1993-8. Epub 2006 Mar 6.

24.

Identification of a receptor-independent activator of G protein signaling (AGS8) in ischemic heart and its interaction with Gbetagamma.

Sato M, Cismowski MJ, Toyota E, Smrcka AV, Lucchesi PA, Chilian WM, Lanier SM.

Proc Natl Acad Sci U S A. 2006 Jan 17;103(3):797-802. Epub 2006 Jan 9.

25.

Accessory proteins for G proteins: partners in signaling.

Sato M, Blumer JB, Simon V, Lanier SM.

Annu Rev Pharmacol Toxicol. 2006;46:151-87. Review.

PMID:
16402902
26.

AGS proteins: receptor-independent activators of G-protein signaling.

Blumer JB, Cismowski MJ, Sato M, Lanier SM.

Trends Pharmacol Sci. 2005 Sep;26(9):470-6. Review.

PMID:
16084602
27.
28.

Influence of the membrane lipid structure on signal processing via G protein-coupled receptors.

Yang Q, Alemany R, Casas J, Kitajka K, Lanier SM, Escribá PV.

Mol Pharmacol. 2005 Jul;68(1):210-7. Epub 2005 Apr 18.

PMID:
15837842
29.

AGS proteins, GPR motifs and the signals processed by heterotrimeric G proteins.

Lanier SM.

Biol Cell. 2004 Jun;96(5):369-72. Review.

PMID:
15207906
30.

The Ras-related protein AGS1/RASD1 suppresses cell growth.

Vaidyanathan G, Cismowski MJ, Wang G, Vincent TS, Brown KD, Lanier SM.

Oncogene. 2004 Jul 29;23(34):5858-63.

PMID:
15184869
31.

Identification and characterization of AGS4: a protein containing three G-protein regulatory motifs that regulate the activation state of Gialpha.

Cao X, Cismowski MJ, Sato M, Blumer JB, Lanier SM.

J Biol Chem. 2004 Jun 25;279(26):27567-74. Epub 2004 Apr 19.

32.

Activator of G protein signaling 3: a gatekeeper of cocaine sensitization and drug seeking.

Bowers MS, McFarland K, Lake RW, Peterson YK, Lapish CC, Gregory ML, Lanier SM, Kalivas PW.

Neuron. 2004 Apr 22;42(2):269-81.

34.

AGS3: a G-Protein regulator of addiction-associated behaviors.

Bowers MS, Lake RW, McFarland K, Peterson YK, Lanier SM, Lapish CC, Kalivas PW.

Ann N Y Acad Sci. 2003 Nov;1003:356-7. No abstract available.

PMID:
14684460
35.

Receptor- and nucleotide exchange-independent mechanisms for promoting G protein subunit dissociation.

Ghosh M, Peterson YK, Lanier SM, Smrcka AV.

J Biol Chem. 2003 Sep 12;278(37):34747-50. Epub 2003 Jul 24.

36.

Influence of cytosolic AGS3 on receptor--G protein coupling.

Ma H, Peterson YK, Bernard ML, Lanier SM, Graber SG.

Biochemistry. 2003 Jul 8;42(26):8085-93.

PMID:
12834360
37.

Asymmetrically distributed C. elegans homologs of AGS3/PINS control spindle position in the early embryo.

Gotta M, Dong Y, Peterson YK, Lanier SM, Ahringer J.

Curr Biol. 2003 Jun 17;13(12):1029-37.

40.

Pertussis toxin-insensitive activation of the heterotrimeric G-proteins Gi/Go by the NG108-15 G-protein activator.

Ribas C, Takesono A, Sato M, Hildebrandt JD, Lanier SM.

J Biol Chem. 2002 Dec 27;277(52):50223-5. Epub 2002 Nov 7.

41.

Activator of G-protein signaling 1 blocks GIRK channel activation by a G-protein-coupled receptor: apparent disruption of receptor signaling complexes.

Takesono A, Nowak MW, Cismowski M, Duzic E, Lanier SM.

J Biol Chem. 2002 Apr 19;277(16):13827-30. Epub 2002 Feb 12.

43.

Protein interaction assays with G proteins.

Wu G, Bernard ML, Lanier SM.

Methods Enzymol. 2002;344:521-35. No abstract available.

PMID:
11771408
44.

Identification of modulators of mammalian G-protein signaling by functional screens in the yeast Saccharomyces cerevisiae.

Cismowski MJ, Takesono A, Ma C, Lanier SM, Duzic E.

Methods Enzymol. 2002;344:153-68. No abstract available.

PMID:
11771380
45.

Analysis of signal transfer from receptor to Go/Gi in different membrane environments and receptor-independent activators of brain G protein.

Ribas C, Sato M, Hildebrandt JD, Lanier SM.

Methods Enzymol. 2002;344:140-52. No abstract available.

PMID:
11771378
46.

Identification of structural features in the G-protein regulatory motif required for regulation of heterotrimeric G-proteins.

Peterson YK, Hazard S 3rd, Graber SG, Lanier SM.

J Biol Chem. 2002 Mar 1;277(9):6767-70. Epub 2001 Dec 27.

47.

Adenylyl cyclase isoforms and signal integration in models of vascular smooth muscle cells.

Webb JG, Yates PW, Yang Q, Mukhin YV, Lanier SM.

Am J Physiol Heart Circ Physiol. 2001 Oct;281(4):H1545-52.

48.

Receptor-independent activators of heterotrimeric G-proteins.

Cismowski MJ, Takesono A, Bernard ML, Duzic E, Lanier SM.

Life Sci. 2001 Apr 6;68(19-20):2301-8. Review.

PMID:
11358340
49.

Identification of a truncated form of the G-protein regulator AGS3 in heart that lacks the tetratricopeptide repeat domains.

Pizzinat N, Takesono A, Lanier SM.

J Biol Chem. 2001 May 18;276(20):16601-10. Epub 2001 Feb 5.

50.

Partial agonist clonidine mediates alpha(2)-AR subtypes specific regulation of cAMP accumulation in adenylyl cyclase II transfected DDT1-MF2 cells.

Limon-Boulez I, Bouet-Alard R, Gettys TW, Lanier SM, Maltier JP, Legrand C.

Mol Pharmacol. 2001 Feb;59(2):331-8.

PMID:
11160870

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