Sort by
Items per page

Send to

Choose Destination

Search results

Items: 17


Blocking the Thrombin Receptor Promotes Repair of Demyelinated Lesions in the Adult Brain.

Yoon H, Choi CI, Triplet EM, Langley MR, Kleppe LS, Kim HN, Simon WL, Scarisbrick IA.

J Neurosci. 2020 Jan 7. pii: 2029-19. doi: 10.1523/JNEUROSCI.2029-19.2019. [Epub ahead of print]


High fat diet consumption results in mitochondrial dysfunction, oxidative stress, and oligodendrocyte loss in the central nervous system.

Langley MR, Yoon H, Kim HN, Choi CI, Simon W, Kleppe L, Lanza IR, LeBrasseur NK, Matveyenko A, Scarisbrick IA.

Biochim Biophys Acta Mol Basis Dis. 2020 Mar 1;1866(3):165630. doi: 10.1016/j.bbadis.2019.165630. Epub 2019 Dec 6.


MitoPark transgenic mouse model recapitulates the gastrointestinal dysfunction and gut-microbiome changes of Parkinson's disease.

Ghaisas S, Langley MR, Palanisamy BN, Dutta S, Narayanaswamy K, Plummer PJ, Sarkar S, Ay M, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG.

Neurotoxicology. 2019 Dec;75:186-199. doi: 10.1016/j.neuro.2019.09.004. Epub 2019 Sep 7.


Loss of the dystonia gene Thap1 leads to transcriptional deficits that converge on common pathogenic pathways in dystonic syndromes.

Frederick NM, Shah PV, Didonna A, Langley MR, Kanthasamy AG, Opal P.

Hum Mol Genet. 2019 Apr 15;28(8):1343-1356. doi: 10.1093/hmg/ddy433.


Inflammasome inhibition prevents α-synuclein pathology and dopaminergic neurodegeneration in mice.

Gordon R, Albornoz EA, Christie DC, Langley MR, Kumar V, Mantovani S, Robertson AAB, Butler MS, Rowe DB, O'Neill LA, Kanthasamy AG, Schroder K, Cooper MA, Woodruff TM.

Sci Transl Med. 2018 Oct 31;10(465). pii: eaah4066. doi: 10.1126/scitranslmed.aah4066.


The Thrombin Receptor Restricts Subventricular Zone Neural Stem Cell Expansion and Differentiation.

Choi CI, Yoon H, Drucker KL, Langley MR, Kleppe L, Scarisbrick IA.

Sci Rep. 2018 Jun 19;8(1):9360. doi: 10.1038/s41598-018-27613-9.


Characterizing a mouse model for evaluation of countermeasures against hydrogen sulfide-induced neurotoxicity and neurological sequelae.

Anantharam P, Whitley EM, Mahama B, Kim DS, Imerman PM, Shao D, Langley MR, Kanthasamy A, Rumbeiha WK.

Ann N Y Acad Sci. 2017 Jul;1400(1):46-64. doi: 10.1111/nyas.13419. Epub 2017 Jul 18.


Manganese exposure exacerbates progressive motor deficits and neurodegeneration in the MitoPark mouse model of Parkinson's disease: Relevance to gene and environment interactions in metal neurotoxicity.

Langley MR, Ghaisas S, Ay M, Luo J, Palanisamy BN, Jin H, Anantharam V, Kanthasamy A, Kanthasamy AG.

Neurotoxicology. 2018 Jan;64:240-255. doi: 10.1016/j.neuro.2017.06.002. Epub 2017 Jun 20.


Prokineticin-2 upregulation during neuronal injury mediates a compensatory protective response against dopaminergic neuronal degeneration.

Gordon R, Neal ML, Luo J, Langley MR, Harischandra DS, Panicker N, Charli A, Jin H, Anantharam V, Woodruff TM, Zhou QY, Kanthasamy AG, Kanthasamy A.

Nat Commun. 2016 Oct 5;7:12932. doi: 10.1038/ncomms12932.


Mitoapocynin Treatment Protects Against Neuroinflammation and Dopaminergic Neurodegeneration in a Preclinical Animal Model of Parkinson's Disease.

Ghosh A, Langley MR, Harischandra DS, Neal ML, Jin H, Anantharam V, Joseph J, Brenza T, Narasimhan B, Kanthasamy A, Kalyanaraman B, Kanthasamy AG.

J Neuroimmune Pharmacol. 2016 Jun;11(2):259-78. doi: 10.1007/s11481-016-9650-4. Epub 2016 Feb 2.


VKORC1 V66M mutation in African Brazilian patients resistant to oral anticoagulant therapy.

Orsi FA, Annichino Bizzacchi JM, de Paula EV, Ozelo MC, Langley MR, Weck KE.

Thromb Res. 2010 Sep;126(3):e206-10. doi: 10.1016/j.thromres.2010.06.008. Epub 2010 Jul 7.


Validation of clinical testing for warfarin sensitivity: comparison of CYP2C9-VKORC1 genotyping assays and warfarin-dosing algorithms.

Langley MR, Booker JK, Evans JP, McLeod HL, Weck KE.

J Mol Diagn. 2009 May;11(3):216-25. doi: 10.2353/jmoldx.2009.080123. Epub 2009 Mar 26.


Comparison of performance characteristics of three real-time reverse transcription-PCR test systems for detection and quantification of hepatitis C virus.

Sábato MF, Shiffman ML, Langley MR, Wilkinson DS, Ferreira-Gonzalez A.

J Clin Microbiol. 2007 Aug;45(8):2529-36. Epub 2007 Jun 13.


The new millennium laboratory: molecular diagnostics goes clinical.

Nadder TS, Langley MR.

Clin Lab Sci. 2001 Fall;14(4):252-259; quiz 260.


Enhanced analytical sensitivity of a quantitative PCR for CMV using a modified nucleic-acid extraction procedure.

Ferreira-Gonzalez A, Yanovich S, Langley MR, Weymouth LA, Wilkinson DS, Garrett CT.

J Clin Lab Anal. 2000;14(1):32-7.


Clinical utility of a quantitative polymerase chain reaction for diagnosis of cytomegalovirus disease in solid organ transplant patients.

Ferreira-Gonzalez A, Fisher RA, Weymouth LA, Langley MR, Wolfe L, Wilkinson DS, Garrett CT.

Transplantation. 1999 Oct 15;68(7):991-6.


Assessing Clinical Utility of Hepatitis C Virus Quantitative RT-PCR Data: Implications for Identification of Responders Among alpha-Interferon-treated Patients.

Ferreira-gonzalez A, Shiffman ML, Lofland DH, Langley MR, Gainey DW, Garrett CT.

Mol Diagn. 1996 Jun;1(2):109-120.


Supplemental Content

Loading ...
Support Center