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Haplotypes spanning centromeric regions reveal persistence of large blocks of archaic DNA.

Langley SA, Miga KH, Karpen GH, Langley CH.

Elife. 2019 Jun 25;8. pii: e42989. doi: 10.7554/eLife.42989.


Design and Evaluation of a New National Pharmacy Internship Program in Ireland.

Strawbridge J, Barlow J, O'Leary A, Spooner M, Clarke E, Arnett R, Langley C, Wilson K, Gallagher P.

Am J Pharm Educ. 2019 May;83(4):6678. doi: 10.5688/ajpe6678.


Development of a highly efficient Axiom™ 70 K SNP array for Pyrus and evaluation for high-density mapping and germplasm characterization.

Montanari S, Bianco L, Allen BJ, Martínez-García PJ, Bassil NV, Postman J, Knäbel M, Kitson B, Deng CH, Chagné D, Crepeau MW, Langley CH, Evans K, Dhingra A, Troggio M, Neale DB.

BMC Genomics. 2019 May 2;20(1):331. doi: 10.1186/s12864-019-5712-3.


Structure of interferon-stimulated gene product 15 (ISG15) from the bat species Myotis davidii and the impact of interdomain ISG15 interactions on viral protein engagement.

Langley C, Goodwin O, Dzimianski JV, Daczkowski CM, Pegan SD.

Acta Crystallogr D Struct Biol. 2019 Jan 1;75(Pt 1):21-31. doi: 10.1107/S2059798318015322. Epub 2019 Jan 4.


Validation and cost-effectiveness of an in-house dithiothreitol (DTT) treatment protocol for daratumumab patients in a large tertiary care hospital provides gateway for implementation in smaller community hospitals.

Youssef M, Arnesen C, Arledge C, Langley C, Sylvester D, Sikora J, Marques MB, Long Zheng X, Williams LA 3rd.

Transfus Apher Sci. 2019 Apr;58(2):152-155. doi: 10.1016/j.transci.2018.12.019. Epub 2019 Jan 6.


A new genomic tool for walnut (Juglans regia L.): development and validation of the high-density Axiom™ J. regia 700K SNP genotyping array.

Marrano A, Martínez-García PJ, Bianco L, Sideli GM, Di Pierro EA, Leslie CA, Stevens KA, Crepeau MW, Troggio M, Langley CH, Neale DB.

Plant Biotechnol J. 2019 Jun;17(6):1027-1036. doi: 10.1111/pbi.13034. Epub 2018 Dec 4.


Novel KAT6B proximal familial variant expands genotypic and phenotypic spectrum.

Yates TM, Langley CLM; DDD Study, Grozeva D, Raymond FL, Johnson DS.

Clin Genet. 2019 Feb;95(2):334-335. doi: 10.1111/cge.13456. Epub 2018 Oct 24. No abstract available.


Genomic architecture of complex traits in loblolly pine.

De La Torre AR, Puiu D, Crepeau MW, Stevens K, Salzberg SL, Langley CH, Neale DB.

New Phytol. 2019 Mar;221(4):1789-1801. doi: 10.1111/nph.15535. Epub 2018 Nov 9.


Hypomorphic caspase activation and recruitment domain 11 (CARD11) mutations associated with diverse immunologic phenotypes with or without atopic disease.

Dorjbal B, Stinson JR, Ma CA, Weinreich MA, Miraghazadeh B, Hartberger JM, Frey-Jakobs S, Weidinger S, Moebus L, Franke A, Schäffer AA, Bulashevska A, Fuchs S, Ehl S, Limaye S, Arkwright PD, Briggs TA, Langley C, Bethune C, Whyte AF, Alachkar H, Nejentsev S, DiMaggio T, Nelson CG, Stone KD, Nason M, Brittain EH, Oler AJ, Veltri DP, Leahy TR, Conlon N, Poli MC, Borzutzky A, Cohen JI, Davis J, Lambert MP, Romberg N, Sullivan KE, Paris K, Freeman AF, Lucas L, Chandrakasan S, Savic S, Hambleton S, Patel SY, Jordan MB, Theos A, Lebensburger J, Atkinson TP, Torgerson TR, Chinn IK, Milner JD, Grimbacher B, Cook MC, Snow AL.

J Allergy Clin Immunol. 2019 Apr;143(4):1482-1495. doi: 10.1016/j.jaci.2018.08.013. Epub 2018 Aug 28.


Growth hormone deficiency as a cause for short stature in Wiedemann-Steiner Syndrome.

Stoyle G, Banka S, Langley C, Jones EA, Banerjee I.

Endocrinol Diabetes Metab Case Rep. 2018 Aug 23;2018. pii: 18-0085. doi: 10.1530/EDM-18-0085. eCollection 2018.


Paper shredder machines: a danger to little fingers. A case of triple finger amputation in a 2-year-old boy.

Clifton LJ, Langley C, McNab I.

J Hand Surg Eur Vol. 2018 Dec;43(10):1116-1118. doi: 10.1177/1753193418783928. Epub 2018 Jun 29. No abstract available.


Sarpagan bridge enzyme has substrate-controlled cyclization and aromatization modes.

Dang TT, Franke J, Carqueijeiro IST, Langley C, Courdavault V, O'Connor SE.

Nat Chem Biol. 2018 Aug;14(8):760-763. doi: 10.1038/s41589-018-0078-4. Epub 2018 Jun 25.


Genomic Variation Among and Within Six Juglans Species.

Stevens KA, Woeste K, Chakraborty S, Crepeau MW, Leslie CA, Martínez-García PJ, Puiu D, Romero-Severson J, Coggeshall M, Dandekar AM, Kluepfel D, Neale DB, Salzberg SL, Langley CH.

G3 (Bethesda). 2018 Jul 2;8(7):2153-2165. doi: 10.1534/g3.118.200030.


Evaluation of RIDA®GENE norovirus GI/GII real time RT-PCR using stool specimens collected from children and adults with acute gastroenteritis.

Kanwar N, Hassan F, Barclay L, Langley C, Vinjé J, Bryant PW, George KS, Mosher L, Matthews-Greer JM, Rocha MA, Beenhouwer DO, Harrison CJ, Moffatt M, Shastri N, Selvarangan R.

J Clin Virol. 2018 Jul;104:1-4. doi: 10.1016/j.jcv.2018.04.006. Epub 2018 Apr 10.


Characterization of Hit Compounds Identified from High-throughput Screening for their Effect on Blood-brain Barrier Integrity and Amyloid-β Clearance: In Vitro and In Vivo Studies.

Elfakhri KH, Duong QV, Langley C, Depaula A, Mousa YM, Lebeouf T, Cain C, Kaddoumi A.

Neuroscience. 2018 May 21;379:269-280. doi: 10.1016/j.neuroscience.2018.03.028. Epub 2018 Mar 26.


Morphologically-directed Raman spectroscopy for forensic soil analysis.

Kammrath BW, Koutrakos A, Castillo J, Langley C, Huck-Jones D.

Forensic Sci Int. 2018 Apr;285:e25-e33. doi: 10.1016/j.forsciint.2017.12.034. Epub 2017 Dec 28.


Clinical pharmacists in general practice: an initial evaluation of activity in one English primary care organisation.

Bush J, Langley CA, Jenkins D, Johal J, Huckerby C.

Int J Pharm Pract. 2018 Dec;26(6):501-506. doi: 10.1111/ijpp.12426. Epub 2017 Dec 27.


Erratum to: An improved assembly of the loblolly pine mega-genome using long-read single-molecule sequencing.

Zimin AV, Stevens KA, Crepeau MW, Puiu D, Wegrzyn JL, Yorke JA, Langley CH, Neale DB, Salzberg SL.

Gigascience. 2017 Oct 1;6(10):1. doi: 10.1093/gigascience/gix072.


The Douglas-Fir Genome Sequence Reveals Specialization of the Photosynthetic Apparatus in Pinaceae.

Neale DB, McGuire PE, Wheeler NC, Stevens KA, Crepeau MW, Cardeno C, Zimin AV, Puiu D, Pertea GM, Sezen UU, Casola C, Koralewski TE, Paul R, Gonzalez-Ibeas D, Zaman S, Cronn R, Yandell M, Holt C, Langley CH, Yorke JA, Salzberg SL, Wegrzyn JL.

G3 (Bethesda). 2017 Sep 7;7(9):3157-3167. doi: 10.1534/g3.117.300078.


An improved assembly of the loblolly pine mega-genome using long-read single-molecule sequencing.

Zimin AV, Stevens KA, Crepeau MW, Puiu D, Wegrzyn JL, Yorke JA, Langley CH, Neale DB, Salzberg SL.

Gigascience. 2017 Jan 1;6(1):1-4. doi: 10.1093/gigascience/giw016. Erratum in: Gigascience. 2017 Oct 1;6(10):1.


From Pine Cones to Read Clouds: Rescaffolding the Megagenome of Sugar Pine (Pinus lambertiana).

Crepeau MW, Langley CH, Stevens KA.

G3 (Bethesda). 2017 May 5;7(5):1563-1568. doi: 10.1534/g3.117.040055.


Rate of Decline in Nontreponemal Antibody Titers and Seroreversion After Treatment of Early Syphilis.

Seña AC, Wolff M, Behets F, Martin DH, Leone P, Langley C, McNeil L, Hook EW 3rd.

Sex Transm Dis. 2017 Jan;44(1):6-10.


Assessing the Gene Content of the Megagenome: Sugar Pine (Pinus lambertiana).

Gonzalez-Ibeas D, Martinez-Garcia PJ, Famula RA, Delfino-Mix A, Stevens KA, Loopstra CA, Langley CH, Neale DB, Wegrzyn JL.

G3 (Bethesda). 2016 Dec 7;6(12):3787-3802. doi: 10.1534/g3.116.032805.


Sequence of the Sugar Pine Megagenome.

Stevens KA, Wegrzyn JL, Zimin A, Puiu D, Crepeau M, Cardeno C, Paul R, Gonzalez-Ibeas D, Koriabine M, Holtz-Morris AE, Martínez-García PJ, Sezen UU, Marçais G, Jermstad K, McGuire PE, Loopstra CA, Davis JM, Eckert A, de Jong P, Yorke JA, Salzberg SL, Neale DB, Langley CH.

Genetics. 2016 Dec;204(4):1613-1626. Epub 2016 Oct 28.


Impact of Two Adolescent Pregnancy Prevention Interventions on Risky Sexual Behavior: A Three-Arm Cluster Randomized Control Trial.

Barbee AP, Cunningham MR, van Zyl MA, Antle BF, Langley CN.

Am J Public Health. 2016 Sep;106(S1):S85-S90.


First Draft Assembly and Annotation of the Genome of a California Endemic Oak Quercus lobata Née (Fagaceae).

Sork VL, Fitz-Gibbon ST, Puiu D, Crepeau M, Gugger PF, Sherman R, Stevens K, Langley CH, Pellegrini M, Salzberg SL.

G3 (Bethesda). 2016 Nov 8;6(11):3485-3495. doi: 10.1534/g3.116.030411.


Hubby and Lewontin on Protein Variation in Natural Populations: When Molecular Genetics Came to the Rescue of Population Genetics.

Charlesworth B, Charlesworth D, Coyne JA, Langley CH.

Genetics. 2016 Aug;203(4):1497-503. doi: 10.1534/genetics.115.185975.


It's a risky business. Midwife-led care and women's perceptions of safety.

Langley C, Lewis M.

Pract Midwife. 2016 Jun;19(6):33-5.


The walnut (Juglans regia) genome sequence reveals diversity in genes coding for the biosynthesis of non-structural polyphenols.

Martínez-García PJ, Crepeau MW, Puiu D, Gonzalez-Ibeas D, Whalen J, Stevens KA, Paul R, Butterfield TS, Britton MT, Reagan RL, Chakraborty S, Walawage SL, Vasquez-Gross HA, Cardeno C, Famula RA, Pratt K, Kuruganti S, Aradhya MK, Leslie CA, Dandekar AM, Salzberg SL, Wegrzyn JL, Langley CH, Neale DB.

Plant J. 2016 Sep;87(5):507-32. doi: 10.1111/tpj.13207. Epub 2016 Jul 18.


Authors' Reply: Evidence-Based Programming of HIV Care and Support: Is the Psychosocial "Optional"?

Kaplan JE, Bateganya MH, Hamm TE, Langley C.

J Acquir Immune Defic Syndr. 2015 Dec 15;70(5):e178-9. doi: 10.1097/QAI.0000000000000840. No abstract available.


Developing a CTG simulator app: theory and practice.

Ford J, Langley C, Molyneux A, Shelton C.

Clin Teach. 2016 Dec;13(6):432-436. doi: 10.1111/tct.12462. Epub 2015 Nov 3.


A comparison of the provision of the My Choice Weight Management Programme via general practitioner practices and community pharmacies in the United Kingdom.

Bush J, Langley C, Mills S, Hindle L.

Clin Obes. 2014 Apr;4(2):91-100. doi: 10.1111/cob.12049. Epub 2014 Mar 6.


Prioritizing HIV care and support interventions-moving from evidence to policy.

Langley CL, Lapidos-Salaiz I, Hamm TE, Bateganya MH, Firth J, Wilson M, Martin J, Dierberg K.

J Acquir Immune Defic Syndr. 2015 Apr 15;68 Suppl 3:S375-8. doi: 10.1097/QAI.0000000000000545. Review. No abstract available.


A systematic review of the effects of visual inspection with acetic acid, cryotherapy, and loop electrosurgical excision procedures for cervical dysplasia in HIV-infected women in low- and middle-income countries.

Forhan SE, Godfrey CC, Watts DH, Langley CL.

J Acquir Immune Defic Syndr. 2015 Apr 15;68 Suppl 3:S350-6. doi: 10.1097/QAI.0000000000000488. Review.


The impact of HIV care and support interventions on key outcomes in low- and middle-income countries: a literature review--introduction.

Kaplan JE, Hamm TE, Forhan S, Saadani Hassani A, Bang G, Weyant E, Tchuenche M, Langley C, Lapidos-Salaiz I, Bateganya MH.

J Acquir Immune Defic Syndr. 2015 Apr 15;68 Suppl 3:S253-6. doi: 10.1097/QAI.0000000000000495. No abstract available.


Children's Perceptions of Hypothetical Peers With Undesirable Characteristics: Role of the Peers' Desire to Change, Source of Effort to Change, and Outcome.

Barnett MA, Sonnentag TL, Wadian TW, Jones TL, Langley CA.

J Genet Psychol. 2015 Jan-Apr;176(1-2):55-63. doi: 10.1080/00221325.2014.1002751. Epub 2015 Feb 19.


The Drosophila genome nexus: a population genomic resource of 623 Drosophila melanogaster genomes, including 197 from a single ancestral range population.

Lack JB, Cardeno CM, Crepeau MW, Taylor W, Corbett-Detig RB, Stevens KA, Langley CH, Pool JE.

Genetics. 2015 Apr;199(4):1229-41. doi: 10.1534/genetics.115.174664. Epub 2015 Jan 27.


Father Knows Best: Paternal Presence and Sexual Debut in African-American Adolescents Living in Poverty.

Langley C.

Fam Process. 2016 Mar;55(1):155-70. doi: 10.1111/famp.12125. Epub 2015 Jan 13.


Nucleosomes shape DNA polymorphism and divergence.

Langley SA, Karpen GH, Langley CH.

PLoS Genet. 2014 Jul 3;10(7):e1004457. doi: 10.1371/journal.pgen.1004457. eCollection 2014 Jul.


A qualitative study of English community pharmacists' experiences of providing lifestyle advice to patients with cardiovascular disease.

Morton K, Pattison H, Langley C, Powell R.

Res Social Adm Pharm. 2015 Jan-Feb;11(1):e17-29. doi: 10.1016/j.sapharm.2014.04.006. Epub 2014 May 9.


Laser-based method and sample handling protocol for measuring breath acetone.

Hancock G, Langley CE, Peverall R, Ritchie GA, Taylor D.

Anal Chem. 2014 Jun 17;86(12):5838-43. doi: 10.1021/ac500614n. Epub 2014 May 29.


Unique features of the loblolly pine (Pinus taeda L.) megagenome revealed through sequence annotation.

Wegrzyn JL, Liechty JD, Stevens KA, Wu LS, Loopstra CA, Vasquez-Gross HA, Dougherty WM, Lin BY, Zieve JJ, Martínez-García PJ, Holt C, Yandell M, Zimin AV, Yorke JA, Crepeau MW, Puiu D, Salzberg SL, Dejong PJ, Mockaitis K, Main D, Langley CH, Neale DB.

Genetics. 2014 Mar;196(3):891-909. doi: 10.1534/genetics.113.159996.


Sequencing and assembly of the 22-gb loblolly pine genome.

Zimin A, Stevens KA, Crepeau MW, Holtz-Morris A, Koriabine M, Marçais G, Puiu D, Roberts M, Wegrzyn JL, de Jong PJ, Neale DB, Salzberg SL, Yorke JA, Langley CH.

Genetics. 2014 Mar;196(3):875-90. doi: 10.1534/genetics.113.159715.


Decoding the massive genome of loblolly pine using haploid DNA and novel assembly strategies.

Neale DB, Wegrzyn JL, Stevens KA, Zimin AV, Puiu D, Crepeau MW, Cardeno C, Koriabine M, Holtz-Morris AE, Liechty JD, Martínez-García PJ, Vasquez-Gross HA, Lin BY, Zieve JJ, Dougherty WM, Fuentes-Soriano S, Wu LS, Gilbert D, Marçais G, Roberts M, Holt C, Yandell M, Davis JM, Smith KE, Dean JF, Lorenz WW, Whetten RW, Sederoff R, Wheeler N, McGuire PE, Main D, Loopstra CA, Mockaitis K, deJong PJ, Yorke JA, Salzberg SL, Langley CH.

Genome Biol. 2014 Mar 4;15(3):R59. doi: 10.1186/gb-2014-15-3-r59.


Differential strengths of positive selection revealed by hitchhiking effects at small physical scales in Drosophila melanogaster.

Lee YC, Langley CH, Begun DJ.

Mol Biol Evol. 2014 Apr;31(4):804-16. doi: 10.1093/molbev/mst270. Epub 2013 Dec 20.


Pharmacy legislation: public protector or professional hindrance?

Langley CA.

Med Law Rev. 2014 Winter;22(1):87-108. doi: 10.1093/medlaw/fwt037. Epub 2013 Dec 9.


The Aston Medication Adherence Study: mapping the adherence patterns of an inner-city population.

Langley CA, Bush J.

Int J Clin Pharm. 2014 Feb;36(1):202-11. doi: 10.1007/s11096-013-9896-3. Epub 2013 Dec 1.


The evolutionary genetics of the genes underlying phenotypic associations for loblolly pine (Pinus taeda, Pinaceae).

Eckert AJ, Wegrzyn JL, Liechty JD, Lee JM, Cumbie WP, Davis JM, Goldfarb B, Loopstra CA, Palle SR, Quesada T, Langley CH, Neale DB.

Genetics. 2013 Dec;195(4):1353-72. doi: 10.1534/genetics.113.157198. Epub 2013 Oct 11.


Insights into the loblolly pine genome: characterization of BAC and fosmid sequences.

Wegrzyn JL, Lin BY, Zieve JJ, Dougherty WM, Martínez-García PJ, Koriabine M, Holtz-Morris A, deJong P, Crepeau M, Langley CH, Puiu D, Salzberg SL, Neale DB, Stevens KA.

PLoS One. 2013 Sep 4;8(9):e72439. doi: 10.1371/journal.pone.0072439. eCollection 2013.


Open access to tree genomes: the path to a better forest.

Neale DB, Langley CH, Salzberg SL, Wegrzyn JL.

Genome Biol. 2013 Jun 24;14(6):120. doi: 10.1186/gb-2013-14-6-120.

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