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Items: 1 to 50 of 581

1.

Computational Identification of Novel Kir6 Channel Inhibitors.

Chen X, Garon A, Wieder M, Houtman MJC, Zangerl-Plessl EM, Langer T, van der Heyden MAG, Stary-Weinzinger A.

Front Pharmacol. 2019 May 24;10:549. doi: 10.3389/fphar.2019.00549. eCollection 2019.

2.

The composition of bacterial communities associated with plastic biofilms differs between different polymers and stages of biofilm succession.

Pinto M, Langer TM, Hüffer T, Hofmann T, Herndl GJ.

PLoS One. 2019 Jun 5;14(6):e0217165. doi: 10.1371/journal.pone.0217165. eCollection 2019.

3.

CerS6-Derived Sphingolipids Interact with Mff and Promote Mitochondrial Fragmentation in Obesity.

Hammerschmidt P, Ostkotte D, Nolte H, Gerl MJ, Jais A, Brunner HL, Sprenger HG, Awazawa M, Nicholls HT, Turpin-Nolan SM, Langer T, Krüger M, Brügger B, Brüning JC.

Cell. 2019 May 30;177(6):1536-1552.e23. doi: 10.1016/j.cell.2019.05.008.

PMID:
31150623
5.

Short-term Physiologic Consequences of Regional Pulmonary Vascular Occlusion in Pigs.

Langer T, Castagna V, Brusatori S, Santini A, Mauri T, Zanella A, Pesenti A.

Anesthesiology. 2019 May 14. doi: 10.1097/ALN.0000000000002735. [Epub ahead of print]

PMID:
31094756
6.

Astrocyte-specific deletion of the mitochondrial m-AAA protease reveals glial contribution to neurodegeneration.

Murru S, Hess S, Barth E, Almajan ER, Schatton D, Hermans S, Brodesser S, Langer T, Kloppenburg P, Rugarli EI.

Glia. 2019 Aug;67(8):1526-1541. doi: 10.1002/glia.23626. Epub 2019 Apr 16.

PMID:
30989755
7.

Genetic Determinants of Ototoxicity During and After Childhood Cancer Treatment: Protocol for the PanCareLIFE Study.

Clemens E, Meijer AJ, Broer L, Langer T, van der Kooi AL, Uitterlinden AG, de Vries A, Kuehni CE, Garrè ML, Kepak T, Kruseova J, Winther JF, Kremer LC, van Dulmen-den Broeder E, Tissing WJ, Rechnitzer C, Kenborg L, Hasle H, Grabow D, Parfitt R, Binder H, Carleton BC, Byrne J, Kaatsch P, Am Zehnhoff-Dinnesen A, Zolk O, van den Heuvel-Eibrink MM.

JMIR Res Protoc. 2019 Mar 19;8(3):e11868. doi: 10.2196/11868.

8.

Leitlinienreport der S3-Leitlinie Diagnostik und Therapie der Plattenepithelkarzinome und Adenokarzinome des Ösophagus.

Porschen R, Langer T, van Leeuwen P.

Z Gastroenterol. 2019 Mar;57(3):e103-e119. doi: 10.1055/a-0833-6106. Epub 2019 Mar 12. German. No abstract available.

PMID:
30861551
Free Article
9.

A proof-of-concept trial of HELIOX with different fractions of helium in a human study modeling upper airway obstruction.

Truebel H, Wuester S, Boehme P, Doll H, Schmiedl S, Szymanski J, Langer T, Ostermann T, Cysarz D, Thuermann P.

Eur J Appl Physiol. 2019 May;119(5):1253-1260. doi: 10.1007/s00421-019-04116-7. Epub 2019 Mar 8.

PMID:
30850876
10.

Structural determinants of lipid specificity within Ups/PRELI lipid transfer proteins.

Miliara X, Tatsuta T, Berry JL, Rouse SL, Solak K, Chorev DS, Wu D, Robinson CV, Matthews S, Langer T.

Nat Commun. 2019 Mar 8;10(1):1130. doi: 10.1038/s41467-019-09089-x.

11.

Interprofessional perceptions and emotional impact of multidrug-resistant organisms: A qualitative study.

Bushuven S, Dietz A, Bushuven S, Dettenkofer M, Langer T.

Am J Infect Control. 2019 Mar 5. pii: S0196-6553(19)30060-4. doi: 10.1016/j.ajic.2019.01.019. [Epub ahead of print]

PMID:
30850246
12.

Health status, Health-Related Quality of Life and Socio-economic Outcome in Childhood Brain Tumor Survivors: a German Cohort Study.

Scholtes C, Baust K, Weinhold L, Creutzig U, Gnekow A, Hinz A, Kaatsch P, Kreitz K, Langer T, Rutkowski S, Singer S, Spix C, Teske C, Schmid M, Dilloo D, Calaminus G.

Neuro Oncol. 2019 Feb 22. pii: noz044. doi: 10.1093/neuonc/noz044. [Epub ahead of print]

PMID:
30793186
13.

Prevention of Cervical Cancer: Guideline of the DGGG and the DKG (S3 Level, AWMF Register Number 015/027OL, December 2017) - Part 2 on Triage, Treatment and Follow-up.

Hillemanns P, Friese K, Dannecker C, Klug S, Seifert U, Iftner T, Hädicke J, Löning T, Horn L, Schmidt D, Ikenberg H, Steiner M, Freitag U, Siebert U, Sroczynski G, Sauerbrei W, Beckmann MW, Gebhardt M, Friedrich M, Münstedt K, Schneider A, Kaufmann A, Petry KU, Schäfer APA, Pawlita M, Weis J, Mehnert A, Fehr M, Grimm C, Reich O, Arbyn M, Kleijnen J, Wesselmann S, Nothacker M, Follmann M, Langer T, Jentschke M.

Geburtshilfe Frauenheilkd. 2019 Feb;79(2):160-176. doi: 10.1055/a-0828-7722. Epub 2019 Feb 18.

14.

Prevention of Cervical Cancer: Guideline of the DGGG and the DKG (S3 Level, AWMF Register Number 015/027OL, December 2017) - Part 1 with Introduction, Screening and the Pathology of Cervical Dysplasia.

Hillemanns P, Friese K, Dannecker C, Klug S, Seifert U, Iftner T, Hädicke J, Löning T, Horn L, Schmidt D, Ikenberg H, Steiner M, Freitag U, Siebert U, Sroczynski G, Sauerbrei W, Beckmann MW, Gebhardt M, Friedrich M, Münstedt K, Schneider A, Kaufmann A, Petry KU, Schäfer APA, Pawlita M, Weis J, Mehnert A, Fehr M, Grimm C, Reich O, Arbyn M, Kleijnen J, Wesselmann S, Nothacker M, Follmann M, Langer T, Jentschke M.

Geburtshilfe Frauenheilkd. 2019 Feb;79(2):148-159. doi: 10.1055/a-0818-5440. Epub 2019 Feb 18.

15.

Enantioselective Aza-Heck Cyclizations of N-(Tosyloxy)carbamates: Synthesis of Pyrrolidines and Piperidines.

Ma X, Hazelden IR, Langer T, Munday RH, Bower JF.

J Am Chem Soc. 2019 Feb 27;141(8):3356-3360. doi: 10.1021/jacs.8b12689. Epub 2019 Feb 18.

PMID:
30775918
16.

Mitochondrial Proteolysis and Metabolic Control.

Ahola S, Langer T, MacVicar T.

Cold Spring Harb Perspect Biol. 2019 Jan 22. pii: a033936. doi: 10.1101/cshperspect.a033936. [Epub ahead of print]

PMID:
30670467
17.

Recommendations for ototoxicity surveillance for childhood, adolescent, and young adult cancer survivors: a report from the International Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCare Consortium.

Clemens E, van den Heuvel-Eibrink MM, Mulder RL, Kremer LCM, Hudson MM, Skinner R, Constine LS, Bass JK, Kuehni CE, Langer T, van Dalen EC, Bardi E, Bonne NX, Brock PR, Brooks B, Carleton B, Caron E, Chang KW, Johnston K, Knight K, Nathan PC, Orgel E, Prasad PK, Rottenberg J, Scheinemann K, de Vries ACH, Walwyn T, Weiss A, Am Zehnhoff-Dinnesen A, Cohn RJ, Landier W; International Guideline Harmonization Group ototoxicity group.

Lancet Oncol. 2019 Jan;20(1):e29-e41. doi: 10.1016/S1470-2045(18)30858-1. Review.

PMID:
30614474
18.

Sustainable Asymmetric Organolithium Chemistry: Enantio- and Chemoselective Acylations through Recycling of Solvent, Sparteine, and Weinreb "Amine".

Monticelli S, Holzer W, Langer T, Roller A, Olofsson B, Pace V.

ChemSusChem. 2019 Mar 21;12(6):1147-1154. doi: 10.1002/cssc.201802815. Epub 2019 Feb 13.

PMID:
30614208
19.

Modular and Chemoselective Strategy for the Direct Access to α-Fluoroepoxides and Aziridines via the Addition of Fluoroiodomethyllithium to Carbonyl-Like Compounds.

Monticelli S, Colella M, Pillari V, Tota A, Langer T, Holzer W, Degennaro L, Luisi R, Pace V.

Org Lett. 2019 Jan 18;21(2):584-588. doi: 10.1021/acs.orglett.8b04001. Epub 2019 Jan 2.

PMID:
30600682
20.

ROMO1 is a constituent of the human presequence translocase required for YME1L protease import.

Richter F, Dennerlein S, Nikolov M, Jans DC, Naumenko N, Aich A, MacVicar T, Linden A, Jakobs S, Urlaub H, Langer T, Rehling P.

J Cell Biol. 2019 Feb 4;218(2):598-614. doi: 10.1083/jcb.201806093. Epub 2018 Dec 31.

21.

Interdisciplinary Diagnosis, Therapy and Follow-up of Patients with Endometrial Cancer. Guideline (S3-Level, AWMF Registry Number 032/034-OL, April 2018) - Part 2 with Recommendations on the Therapy and Follow-up of Endometrial Cancer, Palliative Care, Psycho-oncological/Psychosocial Care/Rehabilitation/Patient Information and Healthcare Facilities.

Emons G, Steiner E, Vordermark D, Uleer C, Bock N, Paradies K, Ortmann O, Aretz S, Mallmann P, Kurzeder C, Hagen V, van Oorschot B, Höcht S, Feyer P, Egerer G, Friedrich M, Cremer W, Prott FJ, Horn LC, Prömpeler H, Langrehr J, Leinung S, Beckmann MW, Kimmig R, Letsch A, Reinhardt M, Alt-Epping B, Kiesel L, Menke J, Gebhardt M, Steinke-Lange V, Rahner N, Lichtenegger W, Zeimet A, Hanf V, Weis J, Mueller M, Henscher U, Schmutzler RK, Meindl A, Hilpert F, Panke JE, Strnad V, Niehues C, Dauelsberg T, Niehoff P, Mayr D, Grab D, Kreißl M, Witteler R, Schorsch A, Mustea A, Petru E, Hübner J, Rose AD, Wight E, Tholen R, Bauerschmitz GJ, Fleisch M, Juhasz-Boess I, Lax S, Runnebaum I, Tempfer C, Nothacker MJ, Blödt S, Follmann M, Langer T, Raatz H, Wesselmann S, Erdogan S.

Geburtshilfe Frauenheilkd. 2018 Nov;78(11):1089-1109. doi: 10.1055/a-0715-2964. Epub 2018 Nov 26.

22.

Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032/045OL, December 2017) - Part 2 with Recommendations for the Therapy of Primary, Recurrent and Advanced Breast Cancer.

Wöckel A, Festl J, Stüber T, Brust K, Krockenberger M, Heuschmann PU, Jírů-Hillmann S, Albert US, Budach W, Follmann M, Janni W, Kopp I, Kreienberg R, Kühn T, Langer T, Nothacker M, Scharl A, Schreer I, Link H, Engel J, Fehm T, Weis J, Welt A, Steckelberg A, Feyer P, König K, Hahne A, Baumgartner T, Kreipe HH, Knoefel WT, Denkinger M, Brucker S, Lüftner D, Kubisch C, Gerlach C, Lebeau A, Siedentopf F, Petersen C, Bartsch HH, Schulz-Wendtland R, Hahn M, Hanf V, Müller-Schimpfle M, Henscher U, Roncarati R, Katalinic A, Heitmann C, Honegger C, Paradies K, Bjelic-Radisic V, Degenhardt F, Wenz F, Rick O, Hölzel D, Zaiss M, Kemper G, Budach V, Denkert C, Gerber B, Tesch H, Hirsmüller S, Sinn HP, Dunst J, Münstedt K, Bick U, Fallenberg E, Tholen R, Hung R, Baumann F, Beckmann MW, Blohmer J, Fasching P, Lux MP, Harbeck N, Hadji P, Hauner H, Heywang-Köbrunner S, Huober J, Hübner J, Jackisch C, Loibl S, Lück HJ, von Minckwitz G, Möbus V, Müller V, Nöthlings U, Schmidt M, Schmutzler R, Schneeweiss A, Schütz F, Stickeler E, Thomssen C, Untch M, Wesselmann S, Bücker A, Buck A, Stangl S.

Geburtshilfe Frauenheilkd. 2018 Nov;78(11):1056-1088. doi: 10.1055/a-0646-4630. Epub 2018 Nov 26.

23.

Discovery of Potent Inhibitors for the Large Neutral Amino Acid Transporter 1 (LAT1) by Structure-Based Methods.

Singh N, Scalise M, Galluccio M, Wieder M, Seidel T, Langer T, Indiveri C, Ecker GF.

Int J Mol Sci. 2018 Dec 21;20(1). pii: E27. doi: 10.3390/ijms20010027.

24.

Telescoped, Divergent, Chemoselective C1 and C1-C1 Homologation of Imine Surrogates: Access to Quaternary Chloro- and Halomethyl-Trifluoromethyl Aziridines.

Ielo L, Touqeer S, Roller A, Langer T, Holzer W, Pace V.

Angew Chem Int Ed Engl. 2019 Feb 18;58(8):2479-2484. doi: 10.1002/anie.201812525. Epub 2019 Jan 24.

PMID:
30548145
25.

LigandScout Remote: A New User-Friendly Interface for HPC and Cloud Resources.

Kainrad T, Hunold S, Seidel T, Langer T.

J Chem Inf Model. 2019 Jan 28;59(1):31-37. doi: 10.1021/acs.jcim.8b00716. Epub 2018 Dec 27.

PMID:
30540457
26.

Navigating Communication Challenges in Clinical Practice: A New Approach to Team Education.

Rachwal CM, Langer T, Trainor BP, Bell MA, Browning DM, Meyer EC.

Crit Care Nurse. 2018 Dec;38(6):15-22. doi: 10.4037/ccn2018748.

PMID:
30504494
27.

Long-Term Endocrine and Metabolic Consequences of Cancer Treatment: A Systematic Review.

Gebauer J, Higham C, Langer T, Denzer C, Brabant G.

Endocr Rev. 2019 Jun 1;40(3):711-767. doi: 10.1210/er.2018-00092.

PMID:
30476004
28.

Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation.

Brandt C, Nolte H, Henschke S, Engström Ruud L, Awazawa M, Morgan DA, Gabel P, Sprenger HG, Hess ME, Günther S, Langer T, Rahmouni K, Fenselau H, Krüger M, Brüning JC.

Cell. 2018 Nov 15;175(5):1321-1335.e20. doi: 10.1016/j.cell.2018.10.015.

29.

Lipin1 deficiency causes sarcoplasmic reticulum stress and chaperone-responsive myopathy.

Rashid T, Nemazanyy I, Paolini C, Tatsuta T, Crespin P, de Villeneuve D, Brodesser S, Benit P, Rustin P, Baraibar MA, Agbulut O, Olivier A, Protasi F, Langer T, Chrast R, de Lonlay P, de Foucauld H, Blaauw B, Pende M.

EMBO J. 2019 Jan 3;38(1). pii: e99576. doi: 10.15252/embj.201899576. Epub 2018 Nov 12.

30.
31.

Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy.

Sprenger HG, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T.

EMBO Mol Med. 2019 Jan;11(1). pii: e9288. doi: 10.15252/emmm.201809288.

32.

Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032/045OL, December 2017) - Part 1 with Recommendations for the Screening, Diagnosis and Therapy of Breast Cancer.

Wöckel A, Festl J, Stüber T, Brust K, Stangl S, Heuschmann PU, Albert US, Budach W, Follmann M, Janni W, Kopp I, Kreienberg R, Kühn T, Langer T, Nothacker M, Scharl A, Schreer I, Link H, Engel J, Fehm T, Weis J, Welt A, Steckelberg A, Feyer P, König K, Hahne A, Kreipe HH, Knoefel WT, Denkinger M, Brucker S, Lüftner D, Kubisch C, Gerlach C, Lebeau A, Siedentopf F, Petersen C, Bartsch HH, Schulz-Wendtland R, Hahn M, Hanf V, Müller-Schimpfle M, Henscher U, Roncarati R, Katalinic A, Heitmann C, Honegger C, Paradies K, Bjelic-Radisic V, Degenhardt F, Wenz F, Rick O, Hölzel D, Zaiss M, Kemper G, Budach V, Denkert C, Gerber B, Tesch H, Hirsmüller S, Sinn HP, Dunst J, Münstedt K, Bick U, Fallenberg E, Tholen R, Hung R, Baumann F, Beckmann MW, Blohmer J, Fasching PA, Lux MP, Harbeck N, Hadji P, Hauner H, Heywang-Köbrunner S, Huober J, Hübner J, Jackisch C, Loibl S, Lück HJ, von Minckwitz G, Möbus V, Müller V, Nöthlings U, Schmidt M, Schmutzler R, Schneeweiss A, Schütz F, Stickeler E, Thomssen C, Untch M, Wesselmann S, Bücker A, Krockenberger M.

Geburtshilfe Frauenheilkd. 2018 Oct;78(10):927-948. doi: 10.1055/a-0646-4522. Epub 2018 Oct 19.

33.

Interdisciplinary Diagnosis, Therapy and Follow-up of Patients with Endometrial Cancer. Guideline (S3-Level, AWMF Registry Nummer 032/034-OL, April 2018) - Part 1 with Recommendations on the Epidemiology, Screening, Diagnosis and Hereditary Factors of Endometrial Cancer.

Emons G, Steiner E, Vordermark D, Uleer C, Bock N, Paradies K, Ortmann O, Aretz S, Mallmann P, Kurzeder C, Hagen V, van Oorschot B, Höcht S, Feyer P, Egerer G, Friedrich M, Cremer W, Prott FJ, Horn LC, Prömpeler H, Langrehr J, Leinung S, Beckmann MW, Kimmig R, Letsch A, Reinhardt M, Alt-Epping B, Kiesel L, Menke J, Gebhardt M, Steinke-Lange V, Rahner N, Lichtenegger W, Zeimet A, Hanf V, Weis J, Mueller M, Henscher U, Schmutzler RK, Meindl A, Hilpert F, Panke JE, Strnad V, Niehues C, Dauelsberg T, Niehoff P, Mayr D, Grab D, Kreißl M, Witteler R, Schorsch A, Mustea A, Petru E, Hübner J, Rose AD, Wight E, Tholen R, Bauerschmitz GJ, Fleisch M, Juhasz-Boess I, Sigurd L, Runnebaum I, Tempfer C, Nothacker MJ, Blödt S, Follmann M, Langer T, Raatz H, Wesselmann S, Erdogan S.

Geburtshilfe Frauenheilkd. 2018 Oct;78(10):949-971. doi: 10.1055/a-0713-1218. Epub 2018 Oct 19.

34.

[Pathological-anatomical diagnosis according to the German lung cancer guideline 2018].

Junker K, Büttner R, Langer T, Ukena D.

Pathologe. 2018 Nov;39(6):589-603. doi: 10.1007/s00292-018-0531-x. German.

PMID:
30357460
35.

The signalling conformation of the insulin receptor ectodomain.

Weis F, Menting JG, Margetts MB, Chan SJ, Xu Y, Tennagels N, Wohlfart P, Langer T, Müller CW, Dreyer MK, Lawrence MC.

Nat Commun. 2018 Oct 24;9(1):4420. doi: 10.1038/s41467-018-06826-6.

36.

Design, Synthesis, and Pharmacological Evaluation of Novel β2/3 Subunit-Selective γ-Aminobutyric Acid Type A (GABAA) Receptor Modulators.

Stadler M, Monticelli S, Seidel T, Luger D, Salzer I, Boehm S, Holzer W, Schwarzer C, Urban E, Khom S, Langer T, Pace V, Hering S.

J Med Chem. 2019 Jan 10;62(1):317-341. doi: 10.1021/acs.jmedchem.8b00859. Epub 2018 Oct 23.

PMID:
30289721
37.

Pharmacophore-based discovery of 2-(phenylamino)aceto-hydrazides as potent eosinophil peroxidase (EPO) inhibitors.

Schuster D, Zederbauer M, Langer T, Kubin A, Furtmüller PG.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):1529-1536. doi: 10.1080/14756366.2018.1512598.

38.

PanCareLIFE: The scientific basis for a European project to improve long-term care regarding fertility, ototoxicity and health-related quality of life after cancer occurring among children and adolescents.

Byrne J, Grabow D, Campbell H, O'Brien K, Bielack S, Am Zehnhoff-Dinnesen A, Calaminus G, Kremer L, Langer T, van den Heuvel-Eibrink MM, van Dulmen-den Broeder E, Baust K, Bautz A, Beck JD, Berger C, Binder H, Borgmann-Staudt A, Broer L, Cario H, Casagranda L, Clemens E, Deuster D, de Vries A, Dirksen U, Falck Winther J, Fosså S, Font-Gonzalez A, Grandage V, Haupt R, Hecker-Nolting S, Hjorth L, Kaiser M, Kenborg L, Kepak T, Kepáková K, Knudsen LE, Krawczuk-Rybak M, Kruseova J, Kuehni CE, Kunstreich M, Kuonen R, Lackner H, Leiper A, Loeffen EAH, Luks A, Modan-Moses D, Mulder R, Parfitt R, Paul NW, Ranft A, Ruud E, Schilling R, Spix C, Stefanowicz J, Strauβ G, Uitterlinden AG, van den Berg M, van der Kooi AL, van Dijk M, van Leeuwen F, Zolk O, Zöller D, Kaatsch P; PanCareLIFE consortium.

Eur J Cancer. 2018 Nov;103:227-237. doi: 10.1016/j.ejca.2018.08.007. Epub 2018 Sep 29.

PMID:
30273888
39.

Intraoperative hypotension is not associated with postoperative cognitive dysfunction in elderly patients undergoing general anesthesia for surgery: results of a randomized controlled pilot trial.

Langer T, Santini A, Zadek F, Chiodi M, Pugni P, Cordolcini V, Bonanomi B, Rosini F, Marcucci M, Valenza F, Marenghi C, Inglese S, Pesenti A, Gattinoni L.

J Clin Anesth. 2019 Feb;52:111-118. doi: 10.1016/j.jclinane.2018.09.021. Epub 2018 Sep 20.

PMID:
30243062
40.

[Late effects following childhood cancer treatment : A special challenge for transition medicine].

Gebauer J, Lehnert H, Schmid SM, Spix C, Stein A, Langer T.

Internist (Berl). 2018 Nov;59(11):1157-1162. doi: 10.1007/s00108-018-0496-0. Review. German.

PMID:
30229367
41.

Ventilatory and integrated physiological responses to chronic hypercapnia in goats.

Burgraff NJ, Neumueller SE, Buchholz K, Langer TM 3rd, Hodges MR, Pan L, Forster HV.

J Physiol. 2018 Nov;596(22):5343-5363. doi: 10.1113/JP276666. Epub 2018 Oct 14.

PMID:
30211447
42.

Homologation of halostannanes with carbenoids: a convenient and straightforward one-step access to α-functionalized organotin reagents.

Touqeer S, Castoldi L, Langer T, Holzer W, Pace V.

Chem Commun (Camb). 2018 Sep 6;54(72):10112-10115. doi: 10.1039/c8cc04786c.

PMID:
30124702
43.

A fully automated three-step protein purification procedure for up to five samples using the NGC chromatography system.

Becker W, Scherer A, Faust C, Bauer DK, Scholtes S, Rao E, Hofmann J, Schauder R, Langer T.

Protein Expr Purif. 2019 Jan;153:1-6. doi: 10.1016/j.pep.2018.08.003. Epub 2018 Aug 10.

PMID:
30102973
44.

GRAIL: GRids of phArmacophore Interaction fieLds.

Schuetz DA, Seidel T, Garon A, Martini R, Körbel M, Ecker GF, Langer T.

J Chem Theory Comput. 2018 Sep 11;14(9):4958-4970. doi: 10.1021/acs.jctc.8b00495. Epub 2018 Aug 20.

PMID:
30075621
45.

The Use of Dynamic Pharmacophore in Computer-Aided Hit Discovery: A Case Study.

Perricone U, Wieder M, Seidel T, Langer T, Padova A.

Methods Mol Biol. 2018;1824:317-333. doi: 10.1007/978-1-4939-8630-9_19.

PMID:
30039416
46.

SAR-Guided Scoring Function and Mutational Validation Reveal the Binding Mode of CGS-8216 at the α1+/γ2- Benzodiazepine Site.

Siebert DCB, Wieder M, Schlener L, Scholze P, Boresch S, Langer T, Schnürch M, Mihovilovic MD, Richter L, Ernst M, Ecker GF.

J Chem Inf Model. 2018 Aug 27;58(8):1682-1696. doi: 10.1021/acs.jcim.8b00199. Epub 2018 Aug 8.

PMID:
30028134
47.

In Silico Workflow for the Discovery of Natural Products Activating the G Protein-Coupled Bile Acid Receptor 1.

Kirchweger B, Kratz JM, Ladurner A, Grienke U, Langer T, Dirsch VM, Rollinger JM.

Front Chem. 2018 Jul 2;6:242. doi: 10.3389/fchem.2018.00242. eCollection 2018.

48.

Conformational Sampling of Small Molecules With iCon: Performance Assessment in Comparison With OMEGA.

Poli G, Seidel T, Langer T.

Front Chem. 2018 Jun 19;6:229. doi: 10.3389/fchem.2018.00229. eCollection 2018.

49.

Pharmacy Practice and Education in Austria.

Langer T, Spreitzer H, Ditfurth T, Stemer G, Atkinson J.

Pharmacy (Basel). 2018 Jun 26;6(3). pii: E55. doi: 10.3390/pharmacy6030055.

50.

Multidisciplinary Late Effects Clinics for Childhood Cancer Survivors in Germany - a Two-Center Study.

Gebauer J, Rieken S, Schuster S, Hahn B, Gebauer N, Meidenbauer N, Brabant G, Metzler M, Langer T.

Oncol Res Treat. 2018;41(7-8):430-436. doi: 10.1159/000488203. Epub 2018 Jun 15.

PMID:
29902787

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