Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 556

1.

Telescoped, Divergent, Chemoselective C1 and C1-C1 Homologation of Imines Surrogates: A Straightforward Access to Quaternary Chloro- and Halomethyl-trifluoromethyl-aziridines.

Ielo L, Touqeer S, Roller A, Langer T, Holzer W, Pace V.

Angew Chem Int Ed Engl. 2018 Dec 11. doi: 10.1002/anie.201812525. [Epub ahead of print]

PMID:
30548145
2.

LigandScout Remote: A new User-Friendly Interface for HPC and Cloud Resources.

Kainrad T, Hunold S, Seidel T, Langer T.

J Chem Inf Model. 2018 Dec 12. doi: 10.1021/acs.jcim.8b00716. [Epub ahead of print]

PMID:
30540457
3.

Navigating Communication Challenges in Clinical Practice: A New Approach to Team Education.

Rachwal CM, Langer T, Trainor BP, Bell MA, Browning DM, Meyer EC.

Crit Care Nurse. 2018 Dec;38(6):15-22. doi: 10.4037/ccn2018748.

PMID:
30504494
4.

Long-term Endocrine and Metabolic consequences of Cancer Treatment: A Systematic Review.

Gebauer J, Higham C, Langer T, Denzer C, Brabant G.

Endocr Rev. 2018 Nov 23. doi: 10.1210/er.2018-00092. [Epub ahead of print]

PMID:
30476004
5.

Food Perception Primes Hepatic ER Homeostasis via Melanocortin-Dependent Control of mTOR Activation.

Brandt C, Nolte H, Henschke S, Engström Ruud L, Awazawa M, Morgan DA, Gabel P, Sprenger HG, Hess ME, Günther S, Langer T, Rahmouni K, Fenselau H, Krüger M, Brüning JC.

Cell. 2018 Nov 15;175(5):1321-1335.e20. doi: 10.1016/j.cell.2018.10.015.

PMID:
30445039
6.

Lipin1 deficiency causes sarcoplasmic reticulum stress and chaperone-responsive myopathy.

Rashid T, Nemazanyy I, Paolini C, Tatsuta T, Crespin P, de Villeneuve D, Brodesser S, Benit P, Rustin P, Baraibar MA, Agbulut O, Olivier A, Protasi F, Langer T, Chrast R, de Lonlay P, de Foucauld H, Blaauw B, Pende M.

EMBO J. 2018 Nov 12. pii: e99576. doi: 10.15252/embj.201899576. [Epub ahead of print]

7.
8.

Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy.

Sprenger HG, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T.

EMBO Mol Med. 2018 Nov 2. pii: e9288. doi: 10.15252/emmm.201809288. [Epub ahead of print]

9.

Interdisciplinary Screening, Diagnosis, Therapy and Follow-up of Breast Cancer. Guideline of the DGGG and the DKG (S3-Level, AWMF Registry Number 032/045OL, December 2017) - Part 1 with Recommendations for the Screening, Diagnosis and Therapy of Breast Cancer.

Wöckel A, Festl J, Stüber T, Brust K, Stangl S, Heuschmann PU, Albert US, Budach W, Follmann M, Janni W, Kopp I, Kreienberg R, Kühn T, Langer T, Nothacker M, Scharl A, Schreer I, Link H, Engel J, Fehm T, Weis J, Welt A, Steckelberg A, Feyer P, König K, Hahne A, Kreipe HH, Knoefel WT, Denkinger M, Brucker S, Lüftner D, Kubisch C, Gerlach C, Lebeau A, Siedentopf F, Petersen C, Bartsch HH, Schulz-Wendtland R, Hahn M, Hanf V, Müller-Schimpfle M, Henscher U, Roncarati R, Katalinic A, Heitmann C, Honegger C, Paradies K, Bjelic-Radisic V, Degenhardt F, Wenz F, Rick O, Hölzel D, Zaiss M, Kemper G, Budach V, Denkert C, Gerber B, Tesch H, Hirsmüller S, Sinn HP, Dunst J, Münstedt K, Bick U, Fallenberg E, Tholen R, Hung R, Baumann F, Beckmann MW, Blohmer J, Fasching PA, Lux MP, Harbeck N, Hadji P, Hauner H, Heywang-Köbrunner S, Huober J, Hübner J, Jackisch C, Loibl S, Lück HJ, von Minckwitz G, Möbus V, Müller V, Nöthlings U, Schmidt M, Schmutzler R, Schneeweiss A, Schütz F, Stickeler E, Thomssen C, Untch M, Wesselmann S, Bücker A, Krockenberger M.

Geburtshilfe Frauenheilkd. 2018 Oct;78(10):927-948. doi: 10.1055/a-0646-4522. Epub 2018 Oct 19.

10.

Interdisciplinary Diagnosis, Therapy and Follow-up of Patients with Endometrial Cancer. Guideline (S3-Level, AWMF Registry Nummer 032/034-OL, April 2018) - Part 1 with Recommendations on the Epidemiology, Screening, Diagnosis and Hereditary Factors of Endometrial Cancer.

Emons G, Steiner E, Vordermark D, Uleer C, Bock N, Paradies K, Ortmann O, Aretz S, Mallmann P, Kurzeder C, Hagen V, van Oorschot B, Höcht S, Feyer P, Egerer G, Friedrich M, Cremer W, Prott FJ, Horn LC, Prömpeler H, Langrehr J, Leinung S, Beckmann MW, Kimmig R, Letsch A, Reinhardt M, Alt-Epping B, Kiesel L, Menke J, Gebhardt M, Steinke-Lange V, Rahner N, Lichtenegger W, Zeimet A, Hanf V, Weis J, Mueller M, Henscher U, Schmutzler RK, Meindl A, Hilpert F, Panke JE, Strnad V, Niehues C, Dauelsberg T, Niehoff P, Mayr D, Grab D, Kreißl M, Witteler R, Schorsch A, Mustea A, Petru E, Hübner J, Rose AD, Wight E, Tholen R, Bauerschmitz GJ, Fleisch M, Juhasz-Boess I, Sigurd L, Runnebaum I, Tempfer C, Nothacker MJ, Blödt S, Follmann M, Langer T, Raatz H, Wesselmann S, Erdogan S.

Geburtshilfe Frauenheilkd. 2018 Oct;78(10):949-971. doi: 10.1055/a-0713-1218. Epub 2018 Oct 19.

11.

[Pathological-anatomical diagnosis according to the German lung cancer guideline 2018].

Junker K, Büttner R, Langer T, Ukena D.

Pathologe. 2018 Nov;39(6):589-603. doi: 10.1007/s00292-018-0531-x. German.

PMID:
30357460
12.

The signalling conformation of the insulin receptor ectodomain.

Weis F, Menting JG, Margetts MB, Chan SJ, Xu Y, Tennagels N, Wohlfart P, Langer T, Müller CW, Dreyer MK, Lawrence MC.

Nat Commun. 2018 Oct 24;9(1):4420. doi: 10.1038/s41467-018-06826-6.

13.

Design, Synthesis, and Pharmacological Evaluation of Novel β2/3 Subunit-Selective γ-Aminobutyric Acid Type A (GABAA) Receptor Modulators.

Stadler M, Monticelli S, Seidel T, Luger D, Salzer I, Boehm S, Holzer W, Schwarzer C, Urban E, Khom S, Langer T, Pace V, Hering S.

J Med Chem. 2018 Oct 23. doi: 10.1021/acs.jmedchem.8b00859. [Epub ahead of print]

PMID:
30289721
14.

Pharmacophore-based discovery of 2-(phenylamino)aceto-hydrazides as potent eosinophil peroxidase (EPO) inhibitors.

Schuster D, Zederbauer M, Langer T, Kubin A, Furtmüller PG.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):1529-1536. doi: 10.1080/14756366.2018.1512598.

15.

PanCareLIFE: The scientific basis for a European project to improve long-term care regarding fertility, ototoxicity and health-related quality of life after cancer occurring among children and adolescents.

Byrne J, Grabow D, Campbell H, O'Brien K, Bielack S, Am Zehnhoff-Dinnesen A, Calaminus G, Kremer L, Langer T, van den Heuvel-Eibrink MM, van Dulmen-den Broeder E, Baust K, Bautz A, Beck JD, Berger C, Binder H, Borgmann-Staudt A, Broer L, Cario H, Casagranda L, Clemens E, Deuster D, de Vries A, Dirksen U, Falck Winther J, Fosså S, Font-Gonzalez A, Grandage V, Haupt R, Hecker-Nolting S, Hjorth L, Kaiser M, Kenborg L, Kepak T, Kepáková K, Knudsen LE, Krawczuk-Rybak M, Kruseova J, Kuehni CE, Kunstreich M, Kuonen R, Lackner H, Leiper A, Loeffen EAH, Luks A, Modan-Moses D, Mulder R, Parfitt R, Paul NW, Ranft A, Ruud E, Schilling R, Spix C, Stefanowicz J, Strauβ G, Uitterlinden AG, van den Berg M, van der Kooi AL, van Dijk M, van Leeuwen F, Zolk O, Zöller D, Kaatsch P; PanCareLIFE consortium.

Eur J Cancer. 2018 Nov;103:227-237. doi: 10.1016/j.ejca.2018.08.007. Epub 2018 Sep 29.

PMID:
30273888
16.

Intraoperative hypotension is not associated with postoperative cognitive dysfunction in elderly patients undergoing general anesthesia for surgery: results of a randomized controlled pilot trial.

Langer T, Santini A, Zadek F, Chiodi M, Pugni P, Cordolcini V, Bonanomi B, Rosini F, Marcucci M, Valenza F, Marenghi C, Inglese S, Pesenti A, Gattinoni L.

J Clin Anesth. 2019 Feb;52:111-118. doi: 10.1016/j.jclinane.2018.09.021. Epub 2018 Sep 20.

PMID:
30243062
17.

[Late effects following childhood cancer treatment : A special challenge for transition medicine].

Gebauer J, Lehnert H, Schmid SM, Spix C, Stein A, Langer T.

Internist (Berl). 2018 Nov;59(11):1157-1162. doi: 10.1007/s00108-018-0496-0. Review. German.

PMID:
30229367
18.

Ventilatory and integrated physiological responses to chronic hypercapnia in goats.

Burgraff NJ, Neumueller SE, Buchholz K, Langer TM 3rd, Hodges MR, Pan L, Forster HV.

J Physiol. 2018 Nov;596(22):5343-5363. doi: 10.1113/JP276666. Epub 2018 Oct 14.

PMID:
30211447
19.

Homologation of halostannanes with carbenoids: a convenient and straightforward one-step access to α-functionalized organotin reagents.

Touqeer S, Castoldi L, Langer T, Holzer W, Pace V.

Chem Commun (Camb). 2018 Sep 6;54(72):10112-10115. doi: 10.1039/c8cc04786c.

PMID:
30124702
20.

A fully automated three-step protein purification procedure for up to five samples using the NGC chromatography system.

Becker W, Scherer A, Faust C, Bauer DK, Scholtes S, Rao E, Hofmann J, Schauder R, Langer T.

Protein Expr Purif. 2019 Jan;153:1-6. doi: 10.1016/j.pep.2018.08.003. Epub 2018 Aug 10.

PMID:
30102973
21.

GRAIL: GRids of phArmacophore Interaction fieLds.

Schuetz DA, Seidel T, Garon A, Martini R, Körbel M, Ecker GF, Langer T.

J Chem Theory Comput. 2018 Sep 11;14(9):4958-4970. doi: 10.1021/acs.jctc.8b00495. Epub 2018 Aug 20.

PMID:
30075621
22.

The Use of Dynamic Pharmacophore in Computer-Aided Hit Discovery: A Case Study.

Perricone U, Wieder M, Seidel T, Langer T, Padova A.

Methods Mol Biol. 2018;1824:317-333. doi: 10.1007/978-1-4939-8630-9_19.

PMID:
30039416
23.

SAR-Guided Scoring Function and Mutational Validation Reveal the Binding Mode of CGS-8216 at the α1+/γ2- Benzodiazepine Site.

Siebert DCB, Wieder M, Schlener L, Scholze P, Boresch S, Langer T, Schnürch M, Mihovilovic MD, Richter L, Ernst M, Ecker GF.

J Chem Inf Model. 2018 Aug 27;58(8):1682-1696. doi: 10.1021/acs.jcim.8b00199. Epub 2018 Aug 8.

PMID:
30028134
24.

In Silico Workflow for the Discovery of Natural Products Activating the G Protein-Coupled Bile Acid Receptor 1.

Kirchweger B, Kratz JM, Ladurner A, Grienke U, Langer T, Dirsch VM, Rollinger JM.

Front Chem. 2018 Jul 2;6:242. doi: 10.3389/fchem.2018.00242. eCollection 2018.

25.

Conformational Sampling of Small Molecules With iCon: Performance Assessment in Comparison With OMEGA.

Poli G, Seidel T, Langer T.

Front Chem. 2018 Jun 19;6:229. doi: 10.3389/fchem.2018.00229. eCollection 2018.

26.

Pharmacy Practice and Education in Austria.

Langer T, Spreitzer H, Ditfurth T, Stemer G, Atkinson J.

Pharmacy (Basel). 2018 Jun 26;6(3). pii: E55. doi: 10.3390/pharmacy6030055.

27.

Multidisciplinary Late Effects Clinics for Childhood Cancer Survivors in Germany - a Two-Center Study.

Gebauer J, Rieken S, Schuster S, Hahn B, Gebauer N, Meidenbauer N, Brabant G, Metzler M, Langer T.

Oncol Res Treat. 2018;41(7-8):430-436. doi: 10.1159/000488203. Epub 2018 Jun 15.

PMID:
29902787
28.

Models of Care for Survivors of Childhood Cancer From Across the Globe: Advancing Survivorship Care in the Next Decade.

Tonorezos ES, Barnea D, Cohn RJ, Cypriano MS, Fresneau BC, Haupt R, Hjorth L, Ishida Y, Kruseova J, Kuehni CE, Kurkure PA, Langer T, Nathan PC, Skeen JE, Skinner R, Tacyildiz N, van den Heuvel-Eibrink MM, Winther JF, Hudson MM, Oeffinger KC.

J Clin Oncol. 2018 Jul 20;36(21):2223-2230. doi: 10.1200/JCO.2017.76.5180. Epub 2018 Jun 6.

PMID:
29874138
29.

The influence of genetic variation on late toxicities in childhood cancer survivors: A review.

Clemens E, van der Kooi ALF, Broer L, van Dulmen-den Broeder E, Visscher H, Kremer L, Tissing W, Loonen J, Ronckers CM, Pluijm SMF, Neggers SJCMM, Zolk O, Langer T, Zehnhoff-Dinnesen AA, Wilson CL, Hudson MM, Carleton B, Laven JSE, Uitterlinden AG, van den Heuvel-Eibrink MM.

Crit Rev Oncol Hematol. 2018 Jun;126:154-167. doi: 10.1016/j.critrevonc.2018.04.001. Epub 2018 Apr 12. Review.

30.

Binding investigation and preliminary optimisation of the 3-amino-1,2,4-triazin-5(2H)-one core for the development of new Fyn inhibitors.

Poli G, Lapillo M, Granchi C, Caciolla J, Mouawad N, Caligiuri I, Rizzolio F, Langer T, Minutolo F, Tuccinardi T.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):956-961. doi: 10.1080/14756366.2018.1469017.

31.

The Mu.Ta.Lig. Chemotheca: A Community-Populated Molecular Database for Multi-Target Ligands Identification and Compound-Repurposing.

Ortuso F, Bagetta D, Maruca A, Talarico C, Bolognesi ML, Haider N, Borges F, Bryant S, Langer T, Senderowitz H, Alcaro S.

Front Chem. 2018 Apr 19;6:130. doi: 10.3389/fchem.2018.00130. eCollection 2018.

32.

Evaluation of Children with SMA Type 1 Under Treatment with Nusinersen within the Expanded Access Program in Germany.

Pechmann A, Langer T, Schorling D, Stein S, Vogt S, Schara U, Kölbel H, Schwartz O, Hahn A, Giese K, Johannsen J, Denecke J, Weiß C, Theophil M, Kirschner J.

J Neuromuscul Dis. 2018;5(2):135-143. doi: 10.3233/JND-180315.

33.

Dissolved organic carbon leaching from plastics stimulates microbial activity in the ocean.

Romera-Castillo C, Pinto M, Langer TM, Álvarez-Salgado XA, Herndl GJ.

Nat Commun. 2018 Apr 12;9(1):1430. doi: 10.1038/s41467-018-03798-5.

34.

Letter to the editor: In reply to Sansone et al.

Langer T, Pechmann A, Wider S, Kirschner J.

Eur J Paediatr Neurol. 2018 Jul;22(4):732. doi: 10.1016/j.ejpn.2018.03.004. Epub 2018 Mar 29. No abstract available.

PMID:
29628153
35.

Complete Genome Sequence of a New Ruminococcaceae Bacterium Isolated from Anaerobic Biomass Hydrolysis.

Hahnke S, Abendroth C, Langer T, Codoñer FM, Ramm P, Porcar M, Luschnig O, Klocke M.

Genome Announc. 2018 Apr 5;6(14). pii: e00030-18. doi: 10.1128/genomeA.00030-18.

36.

Pyrrolidines and Piperidines by Ligand-Enabled Aza-Heck Cyclizations and Cascades of N-(Pentafluorobenzoyloxy)carbamates.

Hazelden IR, Carmona RC, Langer T, Pringle PG, Bower JF.

Angew Chem Int Ed Engl. 2018 Apr 23;57(18):5124-5128. doi: 10.1002/anie.201801109. Epub 2018 Mar 22.

37.

Recurrence of Ewing sarcoma: Is detection by imaging follow-up protocol associated with survival advantage?

Heinemann M, Ranft A, Langer T, Jürgens H, Kreyer J, Vieth V, Schäfers M, Weckesser M, Simon T, Hassenpflug W, Corbacioglu S, Bielack S, Mayer-Steinacker R, Kühne T, van den Berg H, Gelderblom H, Bauer S, Stegger L, Dirksen U.

Pediatr Blood Cancer. 2018 Jul;65(7):e27011. doi: 10.1002/pbc.27011. Epub 2018 Feb 26.

PMID:
29480574
38.

Proteiniborus indolifex sp. nov., isolated from a thermophilic industrial-scale biogas plant.

Hahnke S, Langer T, Klocke M.

Int J Syst Evol Microbiol. 2018 Jan 25. doi: 10.1099/ijsem.0.002591. [Epub ahead of print]

PMID:
29458500
39.

m-AAA proteases, mitochondrial calcium homeostasis and neurodegeneration.

Patron M, Sprenger HG, Langer T.

Cell Res. 2018 Mar;28(3):296-306. doi: 10.1038/cr.2018.17. Epub 2018 Feb 16. Review.

40.

Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase.

Ruf S, Hallur MS, Anchan NK, Swamy IN, Murugesan KR, Sarkar S, Narasimhulu LK, Putta VPRK, Shaik S, Chandrasekar DV, Mane VS, Kadnur SV, Suresh J, Bhamidipati RK, Singh M, Burri RR, Kristam R, Schreuder H, Czech J, Rudolph C, Marker A, Langer T, Mullangi R, Yura T, Gosu R, Kannt A, Dhakshinamoorthy S, Rajagopal S.

Bioorg Med Chem Lett. 2018 Mar 1;28(5):922-925. doi: 10.1016/j.bmcl.2018.01.058. Epub 2018 Jan 31.

PMID:
29433927
41.

A daily single dose of a novel modafinil analogue CE-123 improves memory acquisition and memory retrieval.

Kristofova M, Aher YD, Ilic M, Radoman B, Kalaba P, Dragacevic V, Aher NY, Leban J, Korz V, Zanon L, Neuhaus W, Wieder M, Langer T, Urban E, Sitte HH, Hoeger H, Lubec G, Aradska J.

Behav Brain Res. 2018 May 2;343:83-94. doi: 10.1016/j.bbr.2018.01.032. Epub 2018 Feb 1.

PMID:
29410048
42.

PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria.

Saita S, Tatsuta T, Lampe PA, König T, Ohba Y, Langer T.

EMBO J. 2018 Feb 15;37(4). pii: e97909. doi: 10.15252/embj.201797909. Epub 2018 Jan 4.

PMID:
29301859
43.

A Novel Dopamine Transporter Inhibitor CE-123 Improves Cognitive Flexibility and Maintains Impulsivity in Healthy Male Rats.

Nikiforuk A, Kalaba P, Ilic M, Korz V, Dragačević V, Wackerlig J, Langer T, Höger H, Golebiowska J, Popik P, Lubec G.

Front Behav Neurosci. 2017 Nov 27;11:222. doi: 10.3389/fnbeh.2017.00222. eCollection 2017.

44.

S3-Leitlinie – Kolorektales Karzinom.

Schmiegel W, Buchberger B, Follmann M, Graeven U, Heinemann V, Langer T, Nothacker M, Porschen R, Rödel C, Rösch T, Schmitt W, Wesselmann S, Pox C.

Z Gastroenterol. 2017 Dec;55(12):1344-1498. doi: 10.1055/s-0043-121106. Epub 2017 Dec 6. German. No abstract available.

PMID:
29212104
Free Article
45.

Single-center experience with intrathecal administration of Nusinersen in children with spinal muscular atrophy type 1.

Pechmann A, Langer T, Wider S, Kirschner J.

Eur J Paediatr Neurol. 2018 Jan;22(1):122-127. doi: 10.1016/j.ejpn.2017.11.001. Epub 2017 Nov 21.

PMID:
29208343
46.

Ventilation during extracorporeal support : Why and how.

Pesenti A, Carlesso E, Langer T, Mauri T.

Med Klin Intensivmed Notfmed. 2018 Feb;113(Suppl 1):26-30. doi: 10.1007/s00063-017-0384-8. Epub 2017 Nov 28. Review.

PMID:
29184987
47.

Late Effects and Long-Term Follow-Up after Cancer in Childhood.

Langer T, Grabow D, Steinmann D, Wörmann B, Calaminus G.

Oncol Res Treat. 2017;40(12):746-750. doi: 10.1159/000484936. Epub 2017 Nov 29.

48.

Oncological Rehabilitation and Cancer Survivorship.

Rick O, Langer T.

Oncol Res Treat. 2017;40(12):744. doi: 10.1159/000485188. Epub 2017 Nov 29. No abstract available.

49.

Intravenous fluid therapy for hospitalized and critically ill children: rationale, available drugs and possible side effects.

Langer T, Limuti R, Tommasino C, van Regenmortel N, Duval ELIM, Caironi P, Malbrain MLNG, Pesenti A.

Anaesthesiol Intensive Ther. 2018;50(1):49-58. doi: 10.5603/AIT.a2017.0058. Epub 2017 Nov 18.

50.

Heterocyclic Analogues of Modafinil as Novel, Atypical Dopamine Transporter Inhibitors.

Kalaba P, Aher NY, Ilić M, Dragačević V, Wieder M, Miklosi AG, Zehl M, Wackerlig J, Roller A, Beryozkina T, Radoman B, Saroja SR, Lindner W, Gonzalez EP, Bakulev V, Leban JJ, Sitte HH, Urban E, Langer T, Lubec G.

J Med Chem. 2017 Nov 22;60(22):9330-9348. doi: 10.1021/acs.jmedchem.7b01313. Epub 2017 Nov 9.

PMID:
29091428

Supplemental Content

Loading ...
Support Center