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Items: 1 to 50 of 530

1.

Conformational Sampling of Small Molecules With iCon: Performance Assessment in Comparison With OMEGA.

Poli G, Seidel T, Langer T.

Front Chem. 2018 Jun 19;6:229. doi: 10.3389/fchem.2018.00229. eCollection 2018.

2.

Pharmacy Practice and Education in Austria.

Langer T, Spreitzer H, Ditfurth T, Stemer G, Atkinson J.

Pharmacy (Basel). 2018 Jun 26;6(3). pii: E55. doi: 10.3390/pharmacy6030055.

3.

Multidisciplinary Late Effects Clinics for Childhood Cancer Survivors in Germany - a Two-Center Study.

Gebauer J, Rieken S, Schuster S, Hahn B, Gebauer N, Meidenbauer N, Brabant G, Metzler M, Langer T.

Oncol Res Treat. 2018 Jun 15;41(7-8). doi: 10.1159/000488203. [Epub ahead of print] No abstract available.

PMID:
29902787
4.

Models of Care for Survivors of Childhood Cancer From Across the Globe: Advancing Survivorship Care in the Next Decade.

Tonorezos ES, Barnea D, Cohn RJ, Cypriano MS, Fresneau BC, Haupt R, Hjorth L, Ishida Y, Kruseova J, Kuehni CE, Kurkure PA, Langer T, Nathan PC, Skeen JE, Skinner R, Tacyildiz N, van den Heuvel-Eibrink MM, Winther JF, Hudson MM, Oeffinger KC.

J Clin Oncol. 2018 Jun 6:JCO2017765180. doi: 10.1200/JCO.2017.76.5180. [Epub ahead of print]

PMID:
29874138
5.

The influence of genetic variation on late toxicities in childhood cancer survivors: A review.

Clemens E, van der Kooi ALF, Broer L, van Dulmen-den Broeder E, Visscher H, Kremer L, Tissing W, Loonen J, Ronckers CM, Pluijm SMF, Neggers SJCMM, Zolk O, Langer T, Zehnhoff-Dinnesen AA, Wilson CL, Hudson MM, Carleton B, Laven JSE, Uitterlinden AG, van den Heuvel-Eibrink MM.

Crit Rev Oncol Hematol. 2018 Jun;126:154-167. doi: 10.1016/j.critrevonc.2018.04.001. Epub 2018 Apr 12. Review.

PMID:
29759558
6.

Binding investigation and preliminary optimisation of the 3-amino-1,2,4-triazin-5(2H)-one core for the development of new Fyn inhibitors.

Poli G, Lapillo M, Granchi C, Caciolla J, Mouawad N, Caligiuri I, Rizzolio F, Langer T, Minutolo F, Tuccinardi T.

J Enzyme Inhib Med Chem. 2018 Dec;33(1):956-961. doi: 10.1080/14756366.2018.1469017.

7.

The Mu.Ta.Lig. Chemotheca: A Community-Populated Molecular Database for Multi-Target Ligands Identification and Compound-Repurposing.

Ortuso F, Bagetta D, Maruca A, Talarico C, Bolognesi ML, Haider N, Borges F, Bryant S, Langer T, Senderowitz H, Alcaro S.

Front Chem. 2018 Apr 19;6:130. doi: 10.3389/fchem.2018.00130. eCollection 2018.

8.

Evaluation of Children with SMA Type 1 Under Treatment with Nusinersen within the Expanded Access Program in Germany.

Pechmann A, Langer T, Schorling D, Stein S, Vogt S, Schara U, Kölbel H, Schwartz O, Hahn A, Giese K, Johannsen J, Denecke J, Weiß C, Theophil M, Kirschner J.

J Neuromuscul Dis. 2018;5(2):135-143. doi: 10.3233/JND-180315.

9.

Dissolved organic carbon leaching from plastics stimulates microbial activity in the ocean.

Romera-Castillo C, Pinto M, Langer TM, Álvarez-Salgado XA, Herndl GJ.

Nat Commun. 2018 Apr 12;9(1):1430. doi: 10.1038/s41467-018-03798-5.

10.

Letter to the editor: In reply to Sansone et al.

Langer T, Pechmann A, Wider S, Kirschner J.

Eur J Paediatr Neurol. 2018 Jul;22(4):732. doi: 10.1016/j.ejpn.2018.03.004. Epub 2018 Mar 29. No abstract available.

PMID:
29628153
11.

Complete Genome Sequence of a New Ruminococcaceae Bacterium Isolated from Anaerobic Biomass Hydrolysis.

Hahnke S, Abendroth C, Langer T, Codoñer FM, Ramm P, Porcar M, Luschnig O, Klocke M.

Genome Announc. 2018 Apr 5;6(14). pii: e00030-18. doi: 10.1128/genomeA.00030-18.

12.

Pyrrolidines and Piperidines by Ligand-Enabled Aza-Heck Cyclizations and Cascades of N-(Pentafluorobenzoyloxy)carbamates.

Hazelden IR, Carmona RC, Langer T, Pringle PG, Bower JF.

Angew Chem Int Ed Engl. 2018 Apr 23;57(18):5124-5128. doi: 10.1002/anie.201801109. Epub 2018 Mar 22.

13.

Recurrence of Ewing sarcoma: Is detection by imaging follow-up protocol associated with survival advantage?

Heinemann M, Ranft A, Langer T, Jürgens H, Kreyer J, Vieth V, Schäfers M, Weckesser M, Simon T, Hassenpflug W, Corbacioglu S, Bielack S, Mayer-Steinacker R, Kühne T, van den Berg H, Gelderblom H, Bauer S, Stegger L, Dirksen U.

Pediatr Blood Cancer. 2018 Jul;65(7):e27011. doi: 10.1002/pbc.27011. Epub 2018 Feb 26.

PMID:
29480574
14.

Proteiniborus indolifex sp. nov., isolated from a thermophilic industrial-scale biogas plant.

Hahnke S, Langer T, Klocke M.

Int J Syst Evol Microbiol. 2018 Jan 25. doi: 10.1099/ijsem.0.002591. [Epub ahead of print]

PMID:
29458500
15.

m-AAA proteases, mitochondrial calcium homeostasis and neurodegeneration.

Patron M, Sprenger HG, Langer T.

Cell Res. 2018 Mar;28(3):296-306. doi: 10.1038/cr.2018.17. Epub 2018 Feb 16. Review.

16.

Novel nicotinamide analog as inhibitor of nicotinamide N-methyltransferase.

Ruf S, Hallur MS, Anchan NK, Swamy IN, Murugesan KR, Sarkar S, Narasimhulu LK, Putta VPRK, Shaik S, Chandrasekar DV, Mane VS, Kadnur SV, Suresh J, Bhamidipati RK, Singh M, Burri RR, Kristam R, Schreuder H, Czech J, Rudolph C, Marker A, Langer T, Mullangi R, Yura T, Gosu R, Kannt A, Dhakshinamoorthy S, Rajagopal S.

Bioorg Med Chem Lett. 2018 Mar 1;28(5):922-925. doi: 10.1016/j.bmcl.2018.01.058. Epub 2018 Jan 31.

PMID:
29433927
17.

A daily single dose of a novel modafinil analogue CE-123 improves memory acquisition and memory retrieval.

Kristofova M, Aher YD, Ilic M, Radoman B, Kalaba P, Dragacevic V, Aher NY, Leban J, Korz V, Zanon L, Neuhaus W, Wieder M, Langer T, Urban E, Sitte HH, Hoeger H, Lubec G, Aradska J.

Behav Brain Res. 2018 May 2;343:83-94. doi: 10.1016/j.bbr.2018.01.032. Epub 2018 Feb 1.

PMID:
29410048
18.

PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria.

Saita S, Tatsuta T, Lampe PA, König T, Ohba Y, Langer T.

EMBO J. 2018 Feb 15;37(4). pii: e97909. doi: 10.15252/embj.201797909. Epub 2018 Jan 4.

PMID:
29301859
19.

A Novel Dopamine Transporter Inhibitor CE-123 Improves Cognitive Flexibility and Maintains Impulsivity in Healthy Male Rats.

Nikiforuk A, Kalaba P, Ilic M, Korz V, Dragačević V, Wackerlig J, Langer T, Höger H, Golebiowska J, Popik P, Lubec G.

Front Behav Neurosci. 2017 Nov 27;11:222. doi: 10.3389/fnbeh.2017.00222. eCollection 2017.

20.

S3-Leitlinie – Kolorektales Karzinom.

Schmiegel W, Buchberger B, Follmann M, Graeven U, Heinemann V, Langer T, Nothacker M, Porschen R, Rödel C, Rösch T, Schmitt W, Wesselmann S, Pox C.

Z Gastroenterol. 2017 Dec;55(12):1344-1498. doi: 10.1055/s-0043-121106. Epub 2017 Dec 6. German. No abstract available.

PMID:
29212104
Free Article
21.

Single-center experience with intrathecal administration of Nusinersen in children with spinal muscular atrophy type 1.

Pechmann A, Langer T, Wider S, Kirschner J.

Eur J Paediatr Neurol. 2018 Jan;22(1):122-127. doi: 10.1016/j.ejpn.2017.11.001. Epub 2017 Nov 21.

PMID:
29208343
22.

Ventilation during extracorporeal support : Why and how.

Pesenti A, Carlesso E, Langer T, Mauri T.

Med Klin Intensivmed Notfmed. 2018 Feb;113(Suppl 1):26-30. doi: 10.1007/s00063-017-0384-8. Epub 2017 Nov 28. Review.

PMID:
29184987
23.

Late Effects and Long-Term Follow-Up after Cancer in Childhood.

Langer T, Grabow D, Steinmann D, Wörmann B, Calaminus G.

Oncol Res Treat. 2017;40(12):746-750. doi: 10.1159/000484936. Epub 2017 Nov 29.

PMID:
29183026
24.

Oncological Rehabilitation and Cancer Survivorship.

Rick O, Langer T.

Oncol Res Treat. 2017;40(12):744. doi: 10.1159/000485188. Epub 2017 Nov 29. No abstract available.

25.

Intravenous fluid therapy for hospitalized and critically ill children: rationale, available drugs and possible side effects.

Langer T, Limuti R, Tommasino C, van Regenmortel N, Duval ELIM, Caironi P, Malbrain MLNG, Pesenti A.

Anaesthesiol Intensive Ther. 2018;50(1):49-58. doi: 10.5603/AIT.a2017.0058. Epub 2017 Nov 18.

26.

Heterocyclic Analogues of Modafinil as Novel, Atypical Dopamine Transporter Inhibitors.

Kalaba P, Aher NY, Ilić M, Dragačević V, Wieder M, Miklosi AG, Zehl M, Wackerlig J, Roller A, Beryozkina T, Radoman B, Saroja SR, Lindner W, Gonzalez EP, Bakulev V, Leban JJ, Sitte HH, Urban E, Langer T, Lubec G.

J Med Chem. 2017 Nov 22;60(22):9330-9348. doi: 10.1021/acs.jmedchem.7b01313. Epub 2017 Nov 9.

PMID:
29091428
27.

Molecular Docking and 3D-Pharmacophore Modeling to Study the Interactions of Chalcone Derivatives with Estrogen Receptor Alpha.

Muchtaridi M, Syahidah HN, Subarnas A, Yusuf M, Bryant SD, Langer T.

Pharmaceuticals (Basel). 2017 Oct 16;10(4). pii: E81. doi: 10.3390/ph10040081.

28.

Exploiting a "Beast" in Carbenoid Chemistry: Development of a Straightforward Direct Nucleophilic Fluoromethylation Strategy.

Parisi G, Colella M, Monticelli S, Romanazzi G, Holzer W, Langer T, Degennaro L, Pace V, Luisi R.

J Am Chem Soc. 2017 Oct 4;139(39):13648-13651. doi: 10.1021/jacs.7b07891. Epub 2017 Sep 15.

PMID:
28892363
29.

Expression and purification of the extracellular domains of human glycoprotein VI (GPVI) and the receptor for advanced glycation end products (RAGE) from Rattus norvegicus in Leishmania tarentolae.

Langer T, Corvey C, Kroll K, Boscheinen O, Wendrich T, Dittrich W.

Prep Biochem Biotechnol. 2017 Nov 26;47(10):1008-1015. doi: 10.1080/10826068.2017.1365252. Epub 2017 Aug 31.

PMID:
28857681
30.

Ventilation and neurochemical changes during µ-opioid receptor activation or blockade of excitatory receptors in the hypoglossal motor nucleus of goats.

Langer TM 3rd, Neumueller SE, Crumley E, Burgraff NJ, Talwar S, Hodges MR, Pan L, Forster HV.

J Appl Physiol (1985). 2017 Dec 1;123(6):1532-1544. doi: 10.1152/japplphysiol.00592.2017. Epub 2017 Aug 24.

PMID:
28839004
31.

Spontaneous breathing: a double-edged sword to handle with care.

Mauri T, Cambiaghi B, Spinelli E, Langer T, Grasselli G.

Ann Transl Med. 2017 Jul;5(14):292. doi: 10.21037/atm.2017.06.55. Review.

32.

[Treatment of Morbus Hodgkin in a Child with Congenital Lamellar Ichthyosis].

Ketzer J, Lauten M, Langer T, Demmert M, Ernst F, Stille C, Till AM.

Klin Padiatr. 2017 Nov;229(6):350-351. doi: 10.1055/s-0043-116851. Epub 2017 Aug 14. German. No abstract available.

PMID:
28806844
33.

Evidence and isolation of tetrahedral intermediates formed upon the addition of lithium carbenoids to Weinreb amides and N-acylpyrroles.

Castoldi L, Holzer W, Langer T, Pace V.

Chem Commun (Camb). 2017 Aug 22;53(68):9498-9501. doi: 10.1039/c7cc05215d.

PMID:
28799583
34.

Efficient Access to All-Carbon Quaternary and Tertiary α-Functionalized Homoallyl-type Aldehydes from Ketones.

Pace V, Castoldi L, Mazzeo E, Rui M, Langer T, Holzer W.

Angew Chem Int Ed Engl. 2017 Oct 2;56(41):12677-12682. doi: 10.1002/anie.201706236. Epub 2017 Sep 1.

PMID:
28722252
35.

Crystal structures of monkey and mouse nicotinamide N-methyltransferase (NNMT) bound with end product, 1-methyl nicotinamide.

Swaminathan S, Birudukota S, Thakur MK, Parveen R, Kandan S, Juluri S, Shaik S, Anand NN, Burri RR, Kristam R, Hallur MS, Rajagopal S, Schreuder H, Langer T, Rudolph C, Ruf S, Dhakshinamoorthy S, Gosu R, Kannt A.

Biochem Biophys Res Commun. 2017 Sep 16;491(2):416-422. doi: 10.1016/j.bbrc.2017.07.087. Epub 2017 Jul 15.

PMID:
28720493
36.

Acylglycerol Kinase Mutated in Sengers Syndrome Is a Subunit of the TIM22 Protein Translocase in Mitochondria.

Vukotic M, Nolte H, König T, Saita S, Ananjew M, Krüger M, Tatsuta T, Langer T.

Mol Cell. 2017 Aug 3;67(3):471-483.e7. doi: 10.1016/j.molcel.2017.06.013. Epub 2017 Jul 14.

PMID:
28712724
37.

Prohibitins.

Tatsuta T, Langer T.

Curr Biol. 2017 Jul 10;27(13):R629-R631. doi: 10.1016/j.cub.2017.04.030.

PMID:
28697355
38.

R-Modafinil exerts weak effects on spatial memory acquisition and dentate gyrus synaptic plasticity.

Shanmugasundaram B, Aher YD, Aradska J, Ilic M, Daba Feyissa D, Kalaba P, Aher NY, Dragacevic V, Saber Marouf B, Langer T, Sitte HH, Hoeger H, Lubec G, Korz V.

PLoS One. 2017 Jun 23;12(6):e0179675. doi: 10.1371/journal.pone.0179675. eCollection 2017.

39.

A novel heterocyclic compound improves working memory in the radial arm maze and modulates the dopamine receptor D1R in frontal cortex of the Sprague-Dawley rat.

Hussein AM, Aher YD, Kalaba P, Aher NY, Dragačević V, Radoman B, Ilić M, Leban J, Beryozkina T, Ahmed ABMA, Urban E, Langer T, Lubec G.

Behav Brain Res. 2017 Aug 14;332:308-315. doi: 10.1016/j.bbr.2017.06.023. Epub 2017 Jun 16.

PMID:
28629964
40.

The completely annotated genome and comparative genomics of the Peptoniphilaceae bacterium str. ING2-D1G, a novel acidogenic bacterium isolated from a mesophilic biogas reactor.

Tomazetto G, Hahnke S, Langer T, Wibberg D, Blom J, Maus I, Pühler A, Klocke M, Schlüter A.

J Biotechnol. 2017 Sep 10;257:178-186. doi: 10.1016/j.jbiotec.2017.05.027. Epub 2017 Jun 6.

PMID:
28595834
41.

Outcomes in Duchenne muscular dystrophy: nature, nurture, culture-or all three?

Langer T, Kirschner J.

Dev Med Child Neurol. 2017 Aug;59(8):780-781. doi: 10.1111/dmcn.13474. Epub 2017 Jun 6. No abstract available.

PMID:
28586178
42.

2017 GPOH Guidelines for Diagnosis and Treatment of Patients with Neuroblastic Tumors.

Simon T, Hero B, Schulte JH, Deubzer H, Hundsdoerfer P, von Schweinitz D, Fuchs J, Schmidt M, Prasad V, Krug B, Timmermann B, Leuschner I, Fischer M, Langer T, Astrahantseff K, Berthold F, Lode H, Eggert A.

Klin Padiatr. 2017 May;229(3):147-167. doi: 10.1055/s-0043-103086. Epub 2017 May 30.

PMID:
28561228
43.

Do we really need postoperative ICU management after elective surgery? No, not any more!

Taccone P, Langer T, Grasselli G.

Intensive Care Med. 2017 Jul;43(7):1037-1038. doi: 10.1007/s00134-017-4814-0. Epub 2017 May 18. No abstract available.

PMID:
28523405
44.

Phase-based, high spatial resolution and distributed, static and dynamic strain sensing using Brillouin dynamic gratings in optical fibers.

Bergman A, Langer T, Tur M.

Opt Express. 2017 Mar 6;25(5):5376-5388. doi: 10.1364/OE.25.005376.

PMID:
28380799
45.

PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis.

Saita S, Nolte H, Fiedler KU, Kashkar H, Venne AS, Zahedi RP, Krüger M, Langer T.

Nat Cell Biol. 2017 Apr;19(4):318-328. doi: 10.1038/ncb3488. Epub 2017 Mar 13.

PMID:
28288130
46.

Effects on breathing of agonists to μ-opioid or GABAA receptors dialyzed into the ventral respiratory column of awake and sleeping goats.

Langer TM 3rd, Neumueller SE, Crumley E, Burgraff NJ, Talwar S, Hodges MR, Pan L, Forster HV.

Respir Physiol Neurobiol. 2017 May;239:10-25. doi: 10.1016/j.resp.2017.01.007. Epub 2017 Jan 27.

47.

A Molecular Dynamics-Shared Pharmacophore Approach to Boost Early-Enrichment Virtual Screening: A Case Study on Peroxisome Proliferator-Activated Receptor α.

Perricone U, Wieder M, Seidel T, Langer T, Padova A, Almerico AM, Tutone M.

ChemMedChem. 2017 Aug 22;12(16):1399-1407. doi: 10.1002/cmdc.201600526. Epub 2017 Feb 17.

PMID:
28135036
48.

Recent advancements on the use of 2-methyltetrahydrofuran in organometallic chemistry.

Monticelli S, Castoldi L, Murgia I, Senatore R, Mazzeo E, Wackerlig J, Urban E, Langer T, Pace V.

Monatsh Chem. 2017;148(1):37-48. doi: 10.1007/s00706-016-1879-3. Epub 2016 Dec 7. Review.

49.

Effect of an evidence-based guideline on the treatment of maxillofacial cancer: A prospective analysis.

Wolff KD, Rau A, Ferencz J, Langer T, Kesting M, Nieberler M, Wesselmann S.

J Craniomaxillofac Surg. 2017 Mar;45(3):427-431. doi: 10.1016/j.jcms.2016.12.013. Epub 2016 Dec 20.

PMID:
28108238
50.

Common Hits Approach: Combining Pharmacophore Modeling and Molecular Dynamics Simulations.

Wieder M, Garon A, Perricone U, Boresch S, Seidel T, Almerico AM, Langer T.

J Chem Inf Model. 2017 Feb 27;57(2):365-385. doi: 10.1021/acs.jcim.6b00674. Epub 2017 Jan 20.

PMID:
28072524

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