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Items: 1 to 50 of 1920

1.

BOLA3 Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension.

Yu Q, Tai YY, Tang Y, Zhao J, Negi V, Culley MK, Pilli J, Sun W, Brugger K, Mayr J, Saggar R, Saggar R, Wallace WD, Ross DJ, Waxman AB, Wendell SG, Mullett SJ, Sembrat J, Rojas M, Khan OF, Dahlman JE, Sugahara M, Kagiyama N, Satoh T, Zhang M, Feng N, Gorcsan Iii J, Vargas SO, Haley KJ, Kumar R, Graham BB, Langer R, Anderson DG, Wang B, Shiva S, Bertero T, Chan SY.

Circulation. 2019 Feb 14. doi: 10.1161/CIRCULATIONAHA.118.035889. [Epub ahead of print]

PMID:
30759996
2.

An ingestible self-orienting system for oral delivery of macromolecules.

Abramson A, Caffarel-Salvador E, Khang M, Dellal D, Silverstein D, Gao Y, Frederiksen MR, Vegge A, Hubálek F, Water JJ, Friderichsen AV, Fels J, Kirk RK, Cleveland C, Collins J, Tamang S, Hayward A, Landh T, Buckley ST, Roxhed N, Rahbek U, Langer R, Traverso G.

Science. 2019 Feb 8;363(6427):611-615. doi: 10.1126/science.aau2277.

PMID:
30733413
3.

Chasing the Paradigm: Clinical Translation of 25 Years of Tissue Engineering.

Hoffman T, Khademhosseini A, Langer RS.

Tissue Eng Part A. 2019 Feb 6. doi: 10.1089/ten.TEA.2019.0032. [Epub ahead of print]

PMID:
30727841
4.

Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer.

Chen IX, Chauhan VP, Posada J, Ng MR, Wu MW, Adstamongkonkul P, Huang P, Lindeman N, Langer R, Jain RK.

Proc Natl Acad Sci U S A. 2019 Jan 30. pii: 201815515. doi: 10.1073/pnas.1815515116. [Epub ahead of print]

PMID:
30700545
5.

Delivery technologies for cancer immunotherapy.

Riley RS, June CH, Langer R, Mitchell MJ.

Nat Rev Drug Discov. 2019 Jan 8. doi: 10.1038/s41573-018-0006-z. [Epub ahead of print] Review.

PMID:
30622344
6.

Steroid pretreatment of organ donors does not impact on early rejection and long-term kidney allograft survival: Results from a multicenter randomized, controlled trial.

Reindl-Schwaighofer R, Kainz A, Jelencsics K, Heinzel A, Berlakovich G, Remport Á, Heinze G, Langer R, Oberbauer R.

Am J Transplant. 2019 Jan 7. doi: 10.1111/ajt.15252. [Epub ahead of print]

PMID:
30614649
7.

Inhaled Nanoformulated mRNA Polyplexes for Protein Production in Lung Epithelium.

Patel AK, Kaczmarek JC, Bose S, Kauffman KJ, Mir F, Heartlein MW, DeRosa F, Langer R, Anderson DG.

Adv Mater. 2019 Jan 4:e1805116. doi: 10.1002/adma.201805116. [Epub ahead of print]

PMID:
30609147
8.

Biodegradable wafers releasing Temozolomide and Carmustine for the treatment of brain cancer.

Shapira-Furman T, Serra R, Gorelick N, Doglioli M, Tagliaferri V, Cecia A, Peters M, Kumar A, Rottenberg Y, Langer R, Brem H, Tyler B, Domb AJ.

J Control Release. 2019 Feb 10;295:93-101. doi: 10.1016/j.jconrel.2018.12.048. Epub 2018 Dec 31.

PMID:
30605703
9.

Integrative Clustering in Mass Spectrometry Imaging for Enhanced Patient Stratification.

Balluff B, Buck A, Martin-Lorenzo M, Dewez F, Langer R, McDonnell LA, Walch A, Heeren RMA.

Proteomics Clin Appl. 2019 Jan;13(1):e1800137. doi: 10.1002/prca.201800137. Epub 2019 Jan 4.

PMID:
30580496
10.

Ligands Based on Phosphine-Stabilized Aluminum(I), Boron(I), and Carbon(0).

Vondung L, Jerabek P, Langer R.

Chemistry. 2018 Dec 19. doi: 10.1002/chem.201805123. [Epub ahead of print]

PMID:
30565756
11.

Zig-Zag sp2 Carbon Chains Passing through sp3 Framework - A Driving Force toward Room Temperature Ferromagnetic Graphene.

Tuček J, Hola K, Zoppellaro G, Blonski P, Langer R, Medved M, Susi T, Otyepka M, Zbořil R.

ACS Nano. 2018 Dec 5. doi: 10.1021/acsnano.8b08052. [Epub ahead of print]

PMID:
30516956
12.

Drug loading augmentation in polymeric nanoparticles using a coaxial turbulent jet mixer: Yong investigator perspective.

Lim JM, Cai T, Mandaric S, Chopra S, Han H, Jang S, Il Choi W, Langer R, Farokhzad OC, Karnik R.

J Colloid Interface Sci. 2019 Mar 7;538:45-50. doi: 10.1016/j.jcis.2018.11.029. Epub 2018 Nov 10.

PMID:
30500466
13.

Reactive Dimerization of an N-Heterocyclic Plumbylene: C-H Activation with PbII.

Guthardt R, Oetzel J, Schweizer JI, Bruhn C, Langer R, Maurer M, Vícha J, Shestakova P, Holthausen MC, Siemeling U.

Angew Chem Int Ed Engl. 2019 Jan 28;58(5):1387-1391. doi: 10.1002/anie.201811559. Epub 2019 Jan 3.

PMID:
30457693
14.

Implementation of modern tools in autopsy practice-the way towards contemporary postmortal diagnostics.

Langer R, Tröhler A, Schnüriger B, Trippel M, Blank A, Banz Y, Candinas D, Perren A, Lugli A.

Virchows Arch. 2019 Feb;474(2):149-158. doi: 10.1007/s00428-018-2482-2. Epub 2018 Nov 13.

PMID:
30426205
15.

Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient.

Jent P, Trippel M, Frey M, Pöllinger A, Berezowska S, Langer R, Furrer H, Béguelin C.

Open Forum Infect Dis. 2018 Nov 1;5(11):ofy244. doi: 10.1093/ofid/ofy244. eCollection 2018 Nov.

16.

Publisher Correction: Engineering and physical sciences in oncology: challenges and opportunities.

Mitchell MJ, Jain RK, Langer R.

Nat Rev Cancer. 2018 Nov;18(11):720. doi: 10.1038/s41568-018-0072-x.

17.

[The first five years of Hungary's Eurotransplant membership].

Langer R.

Orv Hetil. 2018 Oct;159(42):1695-1699. doi: 10.1556/650.2018.31230. Hungarian.

PMID:
30334486
18.

Biofilm-Inspired Encapsulation of Probiotics for the Treatment of Complex Infections.

Li Z, Behrens AM, Ginat N, Tzeng SY, Lu X, Sivan S, Langer R, Jaklenec A.

Adv Mater. 2018 Dec;30(51):e1803925. doi: 10.1002/adma.201803925. Epub 2018 Oct 17.

PMID:
30328144
19.

Histology of Nivolumab-Induced Thyroiditis.

Neppl C, Kaderli RM, Trepp R, Schmitt AM, Berger MD, Wehrli M, Seiler CA, Langer R.

Thyroid. 2018 Nov 15. doi: 10.1089/thy.2018.0418. [Epub ahead of print] No abstract available.

PMID:
30319070
20.

Her2-Targeted Therapy Induces Autophagy in Esophageal Adenocarcinoma Cells.

Janser FA, Adams O, Bütler V, Schläfli AM, Dislich B, Seiler CA, Kröll D, Langer R, Tschan MP.

Int J Mol Sci. 2018 Oct 8;19(10). pii: E3069. doi: 10.3390/ijms19103069.

21.

Potent in vivo lung cancer Wnt signaling inhibition via cyclodextrin-LGK974 inclusion complexes.

Guimaraes PPG, Tan M, Tammela T, Wu K, Chung A, Oberli M, Wang K, Spektor R, Riley RS, Viana CTR, Jacks T, Langer R, Mitchell MJ.

J Control Release. 2018 Nov 28;290:75-87. doi: 10.1016/j.jconrel.2018.09.025. Epub 2018 Oct 2.

PMID:
30290244
22.

Cellular-scale probes enable stable chronic subsecond monitoring of dopamine neurochemicals in a rodent model.

Schwerdt HN, Zhang E, Kim MJ, Yoshida T, Stanwicks L, Amemori S, Dagdeviren HE, Langer R, Cima MJ, Graybiel AM.

Commun Biol. 2018 Sep 12;1:144. doi: 10.1038/s42003-018-0147-y. eCollection 2018.

23.

CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway.

Graule J, Uth K, Fischer E, Centeno I, Galván JA, Eichmann M, Rau TT, Langer R, Dawson H, Nitsche U, Traeger P, Berger MD, Schnüriger B, Hädrich M, Studer P, Inderbitzin D, Lugli A, Tschan MP, Zlobec I.

Clin Epigenetics. 2018 Sep 26;10(1):120. doi: 10.1186/s13148-018-0548-2.

24.

β-Aminoacrylate Synthetic Hydrogels: Easily Accessible and Operationally Simple Biomaterials Networks.

Fenton OS, Andresen JL, Paolini M, Langer R.

Angew Chem Int Ed Engl. 2018 Dec 3;57(49):16026-16029. doi: 10.1002/anie.201808452. Epub 2018 Nov 8.

PMID:
30209869
25.

Intracochlear drug delivery: Fluorescent tracer evaluation for quantification of distribution in the cochlear partition.

Ayoob AM, Peppi M, Tandon V, Langer R, Borenstein JT.

Eur J Pharm Sci. 2019 Jan 1;126:49-58. doi: 10.1016/j.ejps.2018.09.007. Epub 2018 Sep 7.

PMID:
30195649
26.

Expression Analysis of Autophagy Related Markers LC3B, p62 and HMGB1 Indicate an Autophagy-Independent Negative Prognostic Impact of High p62 Expression in Pulmonary Squamous Cell Carcinomas.

Langer R, Neppl C, Keller MD, Schmid RA, Tschan MP, Berezowska S.

Cancers (Basel). 2018 Aug 21;10(9). pii: E281. doi: 10.3390/cancers10090281.

27.

Scalable Gastric Resident Systems for Veterinary Application.

Hayward A, Bensel T, Mazdiyasni H, Rogner J, Kirtane AR, Lee YL, Hua T, Bajpayee A, Collins J, McDonnell S, Cleveland C, Lopes A, Wahane A, Langer R, Traverso G.

Sci Rep. 2018 Aug 7;8(1):11816. doi: 10.1038/s41598-018-30212-3.

28.

Genotype-targeted local therapy of glioma.

Shankar GM, Kirtane AR, Miller JJ, Mazdiyasni H, Rogner J, Tai T, Williams EA, Higuchi F, Juratli TA, Tateishi K, Koerner MVA, Tummala SS, Fink AL, Penson T, Schmidt SP, Wojtkiewicz GR, Baig A, Francis JM, Rinne ML, Batten JM, Batchelor TT, Brastianos PK, Curry WT Jr, Barker FG 2nd, Jordan JT, Iafrate AJ, Chi AS, Lennerz JK, Meyerson M, Langer R, Wakimoto H, Traverso G, Cahill DP.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8388-E8394. doi: 10.1073/pnas.1805751115. Epub 2018 Aug 6.

PMID:
30082399
29.

In vivo detection of drug-induced apoptosis in tumors using Raman spectroscopy.

Jonas O, Kang JW, Singh SP, Lammers A, Nguyen FT, Dasari RR, So PTC, Langer R, Cima MJ.

Analyst. 2018 Oct 8;143(20):4836-4839. doi: 10.1039/c8an00913a.

PMID:
30070266
30.

Intracellular Delivery by Membrane Disruption: Mechanisms, Strategies, and Concepts.

Stewart MP, Langer R, Jensen KF.

Chem Rev. 2018 Aug 22;118(16):7409-7531. doi: 10.1021/acs.chemrev.7b00678. Epub 2018 Jul 27.

PMID:
30052023
31.

Reply to the letter to the editor 'Anti-EGFR therapy in oesophagogastric cancer: precise but not enough' by M. Salati and S. Cascinu.

Ruhstaller T, Langer R, Thuss-Patience P, Eisterer W, Stahl M.

Ann Oncol. 2018 Sep 1;29(9):2018. doi: 10.1093/annonc/mdy238. No abstract available.

PMID:
29992287
32.

Nanofibrillar Patches of Commensal Skin Bacteria.

Glinel K, Behrens A, Langer RS, Jaklenec A, Jonas AM.

Biomacromolecules. 2018 Jul 19. doi: 10.1021/acs.biomac.8b00735. [Epub ahead of print]

PMID:
29979873
33.

Ionizable Amino-Polyesters Synthesized via Ring Opening Polymerization of Tertiary Amino-Alcohols for Tissue Selective mRNA Delivery.

Kowalski PS, Capasso Palmiero U, Huang Y, Rudra A, Langer R, Anderson DG.

Adv Mater. 2018 Jul 5:e1801151. doi: 10.1002/adma.201801151. [Epub ahead of print]

PMID:
29975801
34.

Endothelial siRNA delivery in nonhuman primates using ionizable low-molecular weight polymeric nanoparticles.

Khan OF, Kowalski PS, Doloff JC, Tsosie JK, Bakthavatchalu V, Winn CB, Haupt J, Jamiel M, Langer R, Anderson DG.

Sci Adv. 2018 Jun 27;4(6):eaar8409. doi: 10.1126/sciadv.aar8409. eCollection 2018 Jun.

35.

Macroscopic Evaluation of the Trimmed Frozen Block Is a Helpful Tool for Intraoperative Assessment of Resection Margins of Breast Cancer Specimens.

Trippel M, Slotta-Huspenina J, Becker K, Rau T, Paepke S, Maurer-Marti F, Langer R.

Int J Surg Pathol. 2018 Dec;26(8):693-700. doi: 10.1177/1066896918780346. Epub 2018 Jun 28.

PMID:
29953301
36.

Focal, remote-controlled, chronic chemical modulation of brain microstructures.

Ramadi KB, Dagdeviren C, Spencer KC, Joe P, Cotler M, Rousseau E, Nunez-Lopez C, Graybiel AM, Langer R, Cima MJ.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):7254-7259. doi: 10.1073/pnas.1804372115. Epub 2018 Jun 25.

37.
38.

A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas.

Adams O, Janser FA, Dislich B, Berezowska S, Humbert M, Seiler CA, Kroell D, Slotta-Huspenina J, Feith M, Ott K, Tschan MP, Langer R.

PLoS One. 2018 Jun 13;13(6):e0197610. doi: 10.1371/journal.pone.0197610. eCollection 2018.

39.

Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types.

Mead BE, Ordovas-Montanes J, Braun AP, Levy LE, Bhargava P, Szucs MJ, Ammendolia DA, MacMullan MA, Yin X, Hughes TK, Wadsworth MH 2nd, Ahmad R, Rakoff-Nahoum S, Carr SA, Langer R, Collins JJ, Shalek AK, Karp JM.

BMC Biol. 2018 Jun 5;16(1):62. doi: 10.1186/s12915-018-0527-2.

40.

Risk factors for esophageal cancer: emphasis on infectious agents.

El-Zimaity H, Di Pilato V, Novella Ringressi M, Brcic I, Rajendra S, Langer R, Dislich B, Tripathi M, Guindi M, Riddell R.

Ann N Y Acad Sci. 2018 Dec;1434(1):319-332. doi: 10.1111/nyas.13858. Epub 2018 May 31. Review.

PMID:
29851130
41.

An ingestible bacterial-electronic system to monitor gastrointestinal health.

Mimee M, Nadeau P, Hayward A, Carim S, Flanagan S, Jerger L, Collins J, McDonnell S, Swartwout R, Citorik RJ, Bulović V, Langer R, Traverso G, Chandrakasan AP, Lu TK.

Science. 2018 May 25;360(6391):915-918. doi: 10.1126/science.aas9315.

PMID:
29798884
42.

Lymphocytic esophagitis: an update on histologic diagnosis, endoscopic findings, and natural history.

Patil DT, Hammer S, Langer R, Yantiss RK.

Ann N Y Acad Sci. 2018 Dec;1434(1):185-191. doi: 10.1111/nyas.13710. Epub 2018 May 24. Review.

PMID:
29797752
43.

Stabilized single-injection inactivated polio vaccine elicits a strong neutralizing immune response.

Tzeng SY, McHugh KJ, Behrens AM, Rose S, Sugarman JL, Ferber S, Langer R, Jaklenec A.

Proc Natl Acad Sci U S A. 2018 Jun 5;115(23):E5269-E5278. doi: 10.1073/pnas.1720970115. Epub 2018 May 21.

44.

Correction to: MicroRNA expression profiling for the prediction of resistance to neoadjuvant radiochemotherapy in squamous cell carcinoma of the esophagus.

Slotta-Huspenina J, Drecoll E, Feith M, Habermehl D, Combs SE, Weichert W, Bettstetter M, Becker K, Langer R.

J Transl Med. 2018 May 16;16(1):128. doi: 10.1186/s12967-018-1513-8.

45.

A new anthraquinoid ligand for the iron-catalyzed hydrosilylation of carbonyl compounds at room temperature: new insights and kinetics.

Raya-Barón Á, Galdeano-Ruano CP, Oña-Burgos P, Rodríguez-Diéguez A, Langer R, López-Ruiz R, Romero-González R, Kuzu I, Fernández I.

Dalton Trans. 2018 May 29;47(21):7272-7281. doi: 10.1039/c8dt01123k.

PMID:
29766169
46.

Engineering a 3D-Bioprinted Model of Human Heart Valve Disease Using Nanoindentation-Based Biomechanics.

van der Valk DC, van der Ven CFT, Blaser MC, Grolman JM, Wu PJ, Fenton OS, Lee LH, Tibbitt MW, Andresen JL, Wen JR, Ha AH, Buffolo F, van Mil A, Bouten CVC, Body SC, Mooney DJ, Sluijter JPG, Aikawa M, Hjortnaes J, Langer R, Aikawa E.

Nanomaterials (Basel). 2018 May 3;8(5). pii: E296. doi: 10.3390/nano8050296.

47.

Advances in Biomaterials for Drug Delivery.

Fenton OS, Olafson KN, Pillai PS, Mitchell MJ, Langer R.

Adv Mater. 2018 May 7:e1705328. doi: 10.1002/adma.201705328. [Epub ahead of print] Review.

PMID:
29736981
48.

Evaporative Cooling Hydrogel Packaging for Storing Biologics Outside of the Cold Chain.

Ferber S, Behrens AM, McHugh KJ, Rosenberg EM, Linehan AR, Sugarman JL, Jayawardena HSN, Langer R, Jaklenec A.

Adv Healthc Mater. 2018 Jul;7(14):e1800220. doi: 10.1002/adhm.201800220. Epub 2018 May 7.

PMID:
29732715
49.

MicroRNA expression profiling for the prediction of resistance to neoadjuvant radiochemotherapy in squamous cell carcinoma of the esophagus.

Slotta-Huspenina J, Drecoll E, Feith M, Habermehl D, Combs S, Weichert W, Bettstetter M, Becker K, Langer R.

J Transl Med. 2018 Apr 25;16(1):109. doi: 10.1186/s12967-018-1492-9. Erratum in: J Transl Med. 2018 May 16;16(1):128.

50.

Controlling the Growth of Staphylococcus epidermidis by Layer-By-Layer Encapsulation.

Jonas AM, Glinel K, Behrens A, Anselmo AC, Langer RS, Jaklenec A.

ACS Appl Mater Interfaces. 2018 May 16;10(19):16250-16259. doi: 10.1021/acsami.8b01988. Epub 2018 May 3.

PMID:
29693369

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