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Items: 1 to 50 of 1944

1.

Outlooks on Three-Dimensional Printing for Ocular Biomaterials Research.

Fenton OS, Paolini M, Andresen JL, Müller FJ, Langer R.

J Ocul Pharmacol Ther. 2019 Jun 18. doi: 10.1089/jop.2018.0142. [Epub ahead of print]

PMID:
31211652
2.

Physical training over 6 months is associated with improved changes in phase angle, body composition, and blood glucose in healthy young males.

Langer RD, Silva AM, Borges JH, Cirolini VX, Páscoa MA, Guerra-Júnior G, Gonçalves EM.

Am J Hum Biol. 2019 Jun 12:e23275. doi: 10.1002/ajhb.23275. [Epub ahead of print]

PMID:
31187509
3.

Steerable Microinvasive Probes for Localized Drug Delivery to Deep Tissue.

Cotler MJ, Rousseau EB, Ramadi KB, Fang J, Graybiel AM, Langer R, Cima MJ.

Small. 2019 Jun 11:e1901459. doi: 10.1002/smll.201901459. [Epub ahead of print]

PMID:
31183933
4.

Tuning the magnetic properties of graphene derivatives by functional group selection.

Langer R, Błoński P, Otyepka M.

Phys Chem Chem Phys. 2019 Jun 21;21(23):12697-12703. doi: 10.1039/c9cp01677e. Epub 2019 Jun 3.

PMID:
31157338
5.

Multimodal analysis of formalin-fixed and paraffin-embedded tissue by MALDI imaging and fluorescence in situ hybridization for combined genetic and metabolic analysis.

Huber K, Kunzke T, Buck A, Langer R, Luber B, Feuchtinger A, Walch A.

Lab Invest. 2019 May 31. doi: 10.1038/s41374-019-0268-z. [Epub ahead of print]

PMID:
31148595
6.

Chondrogenic, hypertrophic, and osteochondral differentiation of human mesenchymal stem cells on three-dimensionally woven scaffolds.

Larson BL, Yu SN, Park H, Estes BT, Moutos FT, Bloomquist CJ, Wu PB, Welter JF, Langer R, Guilak F, Freed LE.

J Tissue Eng Regen Med. 2019 May 21. doi: 10.1002/term.2899. [Epub ahead of print]

PMID:
31115161
7.

Reprogramming the microenvironment with tumor-selective angiotensin blockers enhances cancer immunotherapy.

Chauhan VP, Chen IX, Tong R, Ng MR, Martin JD, Naxerova K, Wu MW, Huang P, Boucher Y, Kohane DS, Langer R, Jain RK.

Proc Natl Acad Sci U S A. 2019 May 28;116(22):10674-10680. doi: 10.1073/pnas.1819889116. Epub 2019 Apr 30.

PMID:
31040208
8.

Ultra-rapid drug delivery in the oral cavity using ultrasound.

France MM, Del Rio T, Travers H, Raftery E, Xu K, Langer R, Traverso G, Lennerz JK, Schoellhammer CM.

J Control Release. 2019 Apr 27;304:1-6. doi: 10.1016/j.jconrel.2019.04.037. [Epub ahead of print]

PMID:
31039376
9.

Microbial therapeutics: New opportunities for drug delivery.

Jimenez M, Langer R, Traverso G.

J Exp Med. 2019 May 6;216(5):1005-1009. doi: 10.1084/jem.20190609. Epub 2019 Apr 26.

PMID:
31028093
10.

Author Correction: Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA.

Islam MA, Xu Y, Tao W, Ubellacker JM, Lim M, Aum D, Lee GY, Zhou K, Zope H, Yu M, Cao W, Oswald JT, Dinarvand M, Mahmoudi M, Langer R, Kantoff PW, Farokhzad OC, Zetter BR, Shi J.

Nat Biomed Eng. 2018 Dec;2(12):968. doi: 10.1038/s41551-018-0331-x.

PMID:
31015729
11.

Restoration of tumour-growth suppression in vivo via systemic nanoparticle-mediated delivery of PTEN mRNA.

Islam MA, Xu Y, Tao W, Ubellacker JM, Lim M, Aum D, Lee GY, Zhou K, Zope H, Yu M, Cao W, Oswald JT, Dinarvand M, Mahmoudi M, Langer R, Kantoff PW, Farokhzad OC, Zetter BR, Shi J.

Nat Biomed Eng. 2018 Nov;2(11):850-864. doi: 10.1038/s41551-018-0284-0. Epub 2018 Sep 17. Erratum in: Nat Biomed Eng. 2018 Dec;2(12):968.

12.

Quantifying the Donor Strength of Ligand-Stabilized Main Group Fragments.

Maser L, Schneider C, Vondung L, Alig L, Langer R.

J Am Chem Soc. 2019 May 8;141(18):7596-7604. doi: 10.1021/jacs.9b02598. Epub 2019 Apr 25.

PMID:
30998330
13.

Temperature-responsive biometamaterials for gastrointestinal applications.

Babaee S, Pajovic S, Kirtane AR, Shi J, Caffarel-Salvador E, Hess K, Collins JE, Tamang S, Wahane AV, Hayward AM, Mazdiyasni H, Langer R, Traverso G.

Sci Transl Med. 2019 Apr 17;11(488). pii: eaau8581. doi: 10.1126/scitranslmed.aau8581.

PMID:
30996082
14.

Polyimide Electrode-Based Electrical Stimulation Impedes Early Stage Muscle Graft Regeneration.

Srinivasan S, Vyas K, McAvoy M, Calvaresi P, Khan OF, Langer R, Anderson DG, Herr H.

Front Neurol. 2019 Mar 22;10:252. doi: 10.3389/fneur.2019.00252. eCollection 2019.

15.

Polymers for extended-release administration.

Paolini MS, Fenton OS, Bhattacharya C, Andresen JL, Langer R.

Biomed Microdevices. 2019 Apr 8;21(2):45. doi: 10.1007/s10544-019-0386-9.

PMID:
30963297
16.

Reduction of measurement noise in a continuous glucose monitor by coating the sensor with a zwitterionic polymer.

Xie X, Doloff JC, Yesilyurt V, Sadraei A, McGarrigle JJ, Omami M, Veiseh O, Farah S, Isa D, Ghani S, Joshi I, Vegas A, Li J, Wang W, Bader A, Tam HH, Tao J, Chen HJ, Yang B, Williamson KA, Oberholzer J, Langer R, Anderson DG.

Nat Biomed Eng. 2018 Dec;2(12):894-906. doi: 10.1038/s41551-018-0273-3. Epub 2018 Jul 30.

17.

Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques.

Bochenek MA, Veiseh O, Vegas AJ, McGarrigle JJ, Qi M, Marchese E, Omami M, Doloff JC, Mendoza-Elias J, Nourmohammadzadeh M, Khan A, Yeh CC, Xing Y, Isa D, Ghani S, Li J, Landry C, Bader AR, Olejnik K, Chen M, Hollister-Lock J, Wang Y, Greiner DL, Weir GC, Løkensgard Strand B, Rokstad AMA, Lacik I, Langer R, Anderson DG, Oberholzer J.

Nat Biomed Eng. 2018 Nov;2(11):810-821. doi: 10.1038/s41551-018-0275-1. Epub 2018 Aug 13.

18.

A gastric resident drug delivery system for prolonged gram-level dosing of tuberculosis treatment.

Verma M, Vishwanath K, Eweje F, Roxhed N, Grant T, Castaneda M, Steiger C, Mazdiyasni H, Bensel T, Minahan D, Soares V, Salama JAF, Lopes A, Hess K, Cleveland C, Fulop DJ, Hayward A, Collins J, Tamang SM, Hua T, Ikeanyi C, Zeidman G, Mule E, Boominathan S, Popova E, Miller JB, Bellinger AM, Collins D, Leibowitz D, Batra S, Ahuja S, Bajiya M, Batra S, Sarin R, Agarwal U, Khaparde SD, Gupta NK, Gupta D, Bhatnagar AK, Chopra KK, Sharma N, Khanna A, Chowdhury J, Stoner R, Slocum AH, Cima MJ, Furin J, Langer R, Traverso G.

Sci Transl Med. 2019 Mar 13;11(483). pii: eaau6267. doi: 10.1126/scitranslmed.aau6267.

PMID:
30867322
19.

Fat mass predicts food-specific inhibitory control in children.

da Costa KG, Price M, Bortolotti H, de Medeiros Rêgo ML, Cabral DAR, Langer RD, Fernandes GA, Elsangedy HM, Fontes EB.

Physiol Behav. 2019 May 15;204:155-161. doi: 10.1016/j.physbeh.2019.02.031. Epub 2019 Feb 25.

PMID:
30817971
20.

Making the case: developing innovative adherence solutions for the treatment of tuberculosis.

Verma M, Furin J, Langer R, Traverso G.

BMJ Glob Health. 2019 Feb 1;4(1):e001323. doi: 10.1136/bmjgh-2018-001323. eCollection 2019. No abstract available.

21.

Simultaneous spatiotemporal tracking and oxygen sensing of transient implants in vivo using hot-spot MRI and machine learning.

Spanoudaki V, Doloff JC, Huang W, Norcross SR, Farah S, Langer R, Anderson DG.

Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4861-4870. doi: 10.1073/pnas.1815909116. Epub 2019 Feb 26.

PMID:
30808810
22.

BOLA (BolA Family Member 3) Deficiency Controls Endothelial Metabolism and Glycine Homeostasis in Pulmonary Hypertension.

Yu Q, Tai YY, Tang Y, Zhao J, Negi V, Culley MK, Pilli J, Sun W, Brugger K, Mayr J, Saggar R, Saggar R, Wallace WD, Ross DJ, Waxman AB, Wendell SG, Mullett SJ, Sembrat J, Rojas M, Khan OF, Dahlman JE, Sugahara M, Kagiyama N, Satoh T, Zhang M, Feng N, Gorcsan J 3rd, Vargas SO, Haley KJ, Kumar R, Graham BB, Langer R, Anderson DG, Wang B, Shiva S, Bertero T, Chan SY.

Circulation. 2019 May 7;139(19):2238-2255. doi: 10.1161/CIRCULATIONAHA.118.035889.

PMID:
30759996
23.

An ingestible self-orienting system for oral delivery of macromolecules.

Abramson A, Caffarel-Salvador E, Khang M, Dellal D, Silverstein D, Gao Y, Frederiksen MR, Vegge A, Hubálek F, Water JJ, Friderichsen AV, Fels J, Kirk RK, Cleveland C, Collins J, Tamang S, Hayward A, Landh T, Buckley ST, Roxhed N, Rahbek U, Langer R, Traverso G.

Science. 2019 Feb 8;363(6427):611-615. doi: 10.1126/science.aau2277.

PMID:
30733413
24.

Chasing the Paradigm: Clinical Translation of 25 Years of Tissue Engineering.

Hoffman T, Khademhosseini A, Langer R.

Tissue Eng Part A. 2019 May;25(9-10):679-687. doi: 10.1089/ten.TEA.2019.0032.

PMID:
30727841
25.

Blocking CXCR4 alleviates desmoplasia, increases T-lymphocyte infiltration, and improves immunotherapy in metastatic breast cancer.

Chen IX, Chauhan VP, Posada J, Ng MR, Wu MW, Adstamongkonkul P, Huang P, Lindeman N, Langer R, Jain RK.

Proc Natl Acad Sci U S A. 2019 Jan 30. pii: 201815515. doi: 10.1073/pnas.1815515116. [Epub ahead of print]

PMID:
30700545
26.

Delivery technologies for cancer immunotherapy.

Riley RS, June CH, Langer R, Mitchell MJ.

Nat Rev Drug Discov. 2019 Mar;18(3):175-196. doi: 10.1038/s41573-018-0006-z. Review.

27.

Steroid pretreatment of organ donors does not impact on early rejection and long-term kidney allograft survival: Results from a multicenter randomized, controlled trial.

Reindl-Schwaighofer R, Kainz A, Jelencsics K, Heinzel A, Berlakovich G, Remport Á, Heinze G, Langer R, Oberbauer R.

Am J Transplant. 2019 Jun;19(6):1770-1776. doi: 10.1111/ajt.15252. Epub 2019 Feb 1.

28.

Inhaled Nanoformulated mRNA Polyplexes for Protein Production in Lung Epithelium.

Patel AK, Kaczmarek JC, Bose S, Kauffman KJ, Mir F, Heartlein MW, DeRosa F, Langer R, Anderson DG.

Adv Mater. 2019 Feb;31(8):e1805116. doi: 10.1002/adma.201805116. Epub 2019 Jan 4.

PMID:
30609147
29.

Biodegradable wafers releasing Temozolomide and Carmustine for the treatment of brain cancer.

Shapira-Furman T, Serra R, Gorelick N, Doglioli M, Tagliaferri V, Cecia A, Peters M, Kumar A, Rottenberg Y, Langer R, Brem H, Tyler B, Domb AJ.

J Control Release. 2019 Feb 10;295:93-101. doi: 10.1016/j.jconrel.2018.12.048. Epub 2018 Dec 31.

PMID:
30605703
30.

Integrative Clustering in Mass Spectrometry Imaging for Enhanced Patient Stratification.

Balluff B, Buck A, Martin-Lorenzo M, Dewez F, Langer R, McDonnell LA, Walch A, Heeren RMA.

Proteomics Clin Appl. 2019 Jan;13(1):e1800137. doi: 10.1002/prca.201800137. Epub 2019 Jan 4.

31.

Ligands Based on Phosphine-Stabilized Aluminum(I), Boron(I), and Carbon(0).

Vondung L, Jerabek P, Langer R.

Chemistry. 2019 Feb 26;25(12):3068-3076. doi: 10.1002/chem.201805123. Epub 2019 Jan 29.

PMID:
30565756
32.

Zigzag sp2 Carbon Chains Passing through an sp3 Framework: A Driving Force toward Room-Temperature Ferromagnetic Graphene.

Tuček J, Holá K, Zoppellaro G, Błoński P, Langer R, Medved' M, Susi T, Otyepka M, Zbořil R.

ACS Nano. 2018 Dec 26;12(12):12847-12859. doi: 10.1021/acsnano.8b08052. Epub 2018 Dec 10.

PMID:
30516956
33.

Drug loading augmentation in polymeric nanoparticles using a coaxial turbulent jet mixer: Yong investigator perspective.

Lim JM, Cai T, Mandaric S, Chopra S, Han H, Jang S, Il Choi W, Langer R, Farokhzad OC, Karnik R.

J Colloid Interface Sci. 2019 Mar 7;538:45-50. doi: 10.1016/j.jcis.2018.11.029. Epub 2018 Nov 10.

PMID:
30500466
34.

Reactive Dimerization of an N-Heterocyclic Plumbylene: C-H Activation with PbII.

Guthardt R, Oetzel J, Schweizer JI, Bruhn C, Langer R, Maurer M, Vícha J, Shestakova P, Holthausen MC, Siemeling U.

Angew Chem Int Ed Engl. 2019 Jan 28;58(5):1387-1391. doi: 10.1002/anie.201811559. Epub 2019 Jan 3.

PMID:
30457693
35.

Implementation of modern tools in autopsy practice-the way towards contemporary postmortal diagnostics.

Langer R, Tröhler A, Schnüriger B, Trippel M, Blank A, Banz Y, Candinas D, Perren A, Lugli A.

Virchows Arch. 2019 Feb;474(2):149-158. doi: 10.1007/s00428-018-2482-2. Epub 2018 Nov 13.

PMID:
30426205
36.

Fatal Measles Virus Infection After Rituximab-Containing Chemotherapy in a Previously Vaccinated Patient.

Jent P, Trippel M, Frey M, Pöllinger A, Berezowska S, Langer R, Furrer H, Béguelin C.

Open Forum Infect Dis. 2018 Nov 1;5(11):ofy244. doi: 10.1093/ofid/ofy244. eCollection 2018 Nov.

37.

Publisher Correction: Engineering and physical sciences in oncology: challenges and opportunities.

Mitchell MJ, Jain RK, Langer R.

Nat Rev Cancer. 2018 Nov;18(11):720. doi: 10.1038/s41568-018-0072-x.

38.

[The first five years of Hungary's Eurotransplant membership].

Langer R.

Orv Hetil. 2018 Oct;159(42):1695-1699. doi: 10.1556/650.2018.31230. Hungarian.

PMID:
30334486
39.

Biofilm-Inspired Encapsulation of Probiotics for the Treatment of Complex Infections.

Li Z, Behrens AM, Ginat N, Tzeng SY, Lu X, Sivan S, Langer R, Jaklenec A.

Adv Mater. 2018 Dec;30(51):e1803925. doi: 10.1002/adma.201803925. Epub 2018 Oct 17.

PMID:
30328144
40.

Histology of Nivolumab-Induced Thyroiditis.

Neppl C, Kaderli RM, Trepp R, Schmitt AM, Berger MD, Wehrli M, Seiler CA, Langer R.

Thyroid. 2018 Nov 15. doi: 10.1089/thy.2018.0418. [Epub ahead of print] No abstract available.

PMID:
30319070
41.

Her2-Targeted Therapy Induces Autophagy in Esophageal Adenocarcinoma Cells.

Janser FA, Adams O, Bütler V, Schläfli AM, Dislich B, Seiler CA, Kröll D, Langer R, Tschan MP.

Int J Mol Sci. 2018 Oct 8;19(10). pii: E3069. doi: 10.3390/ijms19103069.

42.

Potent in vivo lung cancer Wnt signaling inhibition via cyclodextrin-LGK974 inclusion complexes.

Guimaraes PPG, Tan M, Tammela T, Wu K, Chung A, Oberli M, Wang K, Spektor R, Riley RS, Viana CTR, Jacks T, Langer R, Mitchell MJ.

J Control Release. 2018 Nov 28;290:75-87. doi: 10.1016/j.jconrel.2018.09.025. Epub 2018 Oct 2.

PMID:
30290244
43.

Cellular-scale probes enable stable chronic subsecond monitoring of dopamine neurochemicals in a rodent model.

Schwerdt HN, Zhang E, Kim MJ, Yoshida T, Stanwicks L, Amemori S, Dagdeviren HE, Langer R, Cima MJ, Graybiel AM.

Commun Biol. 2018 Sep 12;1:144. doi: 10.1038/s42003-018-0147-y. eCollection 2018.

44.

CDX2 in colorectal cancer is an independent prognostic factor and regulated by promoter methylation and histone deacetylation in tumors of the serrated pathway.

Graule J, Uth K, Fischer E, Centeno I, Galván JA, Eichmann M, Rau TT, Langer R, Dawson H, Nitsche U, Traeger P, Berger MD, Schnüriger B, Hädrich M, Studer P, Inderbitzin D, Lugli A, Tschan MP, Zlobec I.

Clin Epigenetics. 2018 Sep 26;10(1):120. doi: 10.1186/s13148-018-0548-2.

45.

β-Aminoacrylate Synthetic Hydrogels: Easily Accessible and Operationally Simple Biomaterials Networks.

Fenton OS, Andresen JL, Paolini M, Langer R.

Angew Chem Int Ed Engl. 2018 Dec 3;57(49):16026-16029. doi: 10.1002/anie.201808452. Epub 2018 Nov 8.

PMID:
30209869
46.

Intracochlear drug delivery: Fluorescent tracer evaluation for quantification of distribution in the cochlear partition.

Ayoob AM, Peppi M, Tandon V, Langer R, Borenstein JT.

Eur J Pharm Sci. 2019 Jan 1;126:49-58. doi: 10.1016/j.ejps.2018.09.007. Epub 2018 Sep 7.

PMID:
30195649
47.

Expression Analysis of Autophagy Related Markers LC3B, p62 and HMGB1 Indicate an Autophagy-Independent Negative Prognostic Impact of High p62 Expression in Pulmonary Squamous Cell Carcinomas.

Langer R, Neppl C, Keller MD, Schmid RA, Tschan MP, Berezowska S.

Cancers (Basel). 2018 Aug 21;10(9). pii: E281. doi: 10.3390/cancers10090281.

48.

Scalable Gastric Resident Systems for Veterinary Application.

Hayward A, Bensel T, Mazdiyasni H, Rogner J, Kirtane AR, Lee YL, Hua T, Bajpayee A, Collins J, McDonnell S, Cleveland C, Lopes A, Wahane A, Langer R, Traverso G.

Sci Rep. 2018 Aug 7;8(1):11816. doi: 10.1038/s41598-018-30212-3.

49.

Genotype-targeted local therapy of glioma.

Shankar GM, Kirtane AR, Miller JJ, Mazdiyasni H, Rogner J, Tai T, Williams EA, Higuchi F, Juratli TA, Tateishi K, Koerner MVA, Tummala SS, Fink AL, Penson T, Schmidt SP, Wojtkiewicz GR, Baig A, Francis JM, Rinne ML, Batten JM, Batchelor TT, Brastianos PK, Curry WT Jr, Barker FG 2nd, Jordan JT, Iafrate AJ, Chi AS, Lennerz JK, Meyerson M, Langer R, Wakimoto H, Traverso G, Cahill DP.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8388-E8394. doi: 10.1073/pnas.1805751115. Epub 2018 Aug 6.

50.

In vivo detection of drug-induced apoptosis in tumors using Raman spectroscopy.

Jonas O, Kang JW, Singh SP, Lammers A, Nguyen FT, Dasari RR, So PTC, Langer R, Cima MJ.

Analyst. 2018 Oct 8;143(20):4836-4839. doi: 10.1039/c8an00913a.

PMID:
30070266

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