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Items: 1 to 50 of 1897

1.

B-Aminoacrylate Synthetic Hydrogels: Easily Accessible and Operationally Simple Biomaterials Networks.

Fenton O, Andresen J, Paolini M, Langer R.

Angew Chem Int Ed Engl. 2018 Sep 12. doi: 10.1002/anie.201808452. [Epub ahead of print]

PMID:
30209869
2.

Intracochlear drug delivery: Fluorescent tracer evaluation for quantification of distribution in the cochlear partition.

Ayoob AM, Peppi M, Tandon V, Langer R, Borenstein JT.

Eur J Pharm Sci. 2018 Sep 6. pii: S0928-0987(18)30422-6. doi: 10.1016/j.ejps.2018.09.007. [Epub ahead of print]

PMID:
30195649
3.

Expression Analysis of Autophagy Related Markers LC3B, p62 and HMGB1 Indicate an Autophagy-Independent Negative Prognostic Impact of High p62 Expression in Pulmonary Squamous Cell Carcinomas.

Langer R, Neppl C, Keller MD, Schmid RA, Tschan MP, Berezowska S.

Cancers (Basel). 2018 Aug 21;10(9). pii: E281. doi: 10.3390/cancers10090281.

4.

Scalable Gastric Resident Systems for Veterinary Application.

Hayward A, Bensel T, Mazdiyasni H, Rogner J, Kirtane AR, Lee YL, Hua T, Bajpayee A, Collins J, McDonnell S, Cleveland C, Lopes A, Wahane A, Langer R, Traverso G.

Sci Rep. 2018 Aug 7;8(1):11816. doi: 10.1038/s41598-018-30212-3.

5.

Genotype-targeted local therapy of glioma.

Shankar GM, Kirtane AR, Miller JJ, Mazdiyasni H, Rogner J, Tai T, Williams EA, Higuchi F, Juratli TA, Tateishi K, Koerner MVA, Tummala SS, Fink AL, Penson T, Schmidt SP, Wojtkiewicz GR, Baig A, Francis JM, Rinne ML, Batten JM, Batchelor TT, Brastianos PK, Curry WT Jr, Barker FG 2nd, Jordan JT, Iafrate AJ, Chi AS, Lennerz JK, Meyerson M, Langer R, Wakimoto H, Traverso G, Cahill DP.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8388-E8394. doi: 10.1073/pnas.1805751115. Epub 2018 Aug 6.

PMID:
30082399
6.

In vivo detection of drug-induced apoptosis in tumors using Raman spectroscopy.

Jonas O, Kang JW, Singh SP, Lammers A, Nguyen FT, Dasari RR, So PTC, Langer R, Cima MJ.

Analyst. 2018 Aug 2. doi: 10.1039/c8an00913a. [Epub ahead of print]

PMID:
30070266
7.

Intracellular Delivery by Membrane Disruption: Mechanisms, Strategies, and Concepts.

Stewart MP, Langer R, Jensen KF.

Chem Rev. 2018 Aug 22;118(16):7409-7531. doi: 10.1021/acs.chemrev.7b00678. Epub 2018 Jul 27.

PMID:
30052023
8.

Reply to the letter to the editor "Anti-EGFR therapy in oesophagogastric cancer: precise but not enough" by M. Salati and S. Cascinu.

Ruhstaller T, Langer R, Thuss-Patience P, Eisterer W, Stahl M.

Ann Oncol. 2018 Jul 9. doi: 10.1093/annonc/mdy238. [Epub ahead of print] No abstract available.

PMID:
29992287
9.

Nanofibrillar Patches of Commensal Skin Bacteria.

Glinel K, Behrens A, Langer RS, Jaklenec A, Jonas AM.

Biomacromolecules. 2018 Jul 19. doi: 10.1021/acs.biomac.8b00735. [Epub ahead of print]

PMID:
29979873
10.

Ionizable Amino-Polyesters Synthesized via Ring Opening Polymerization of Tertiary Amino-Alcohols for Tissue Selective mRNA Delivery.

Kowalski PS, Capasso Palmiero U, Huang Y, Rudra A, Langer R, Anderson DG.

Adv Mater. 2018 Jul 5:e1801151. doi: 10.1002/adma.201801151. [Epub ahead of print]

PMID:
29975801
11.

Endothelial siRNA delivery in nonhuman primates using ionizable low-molecular weight polymeric nanoparticles.

Khan OF, Kowalski PS, Doloff JC, Tsosie JK, Bakthavatchalu V, Winn CB, Haupt J, Jamiel M, Langer R, Anderson DG.

Sci Adv. 2018 Jun 27;4(6):eaar8409. doi: 10.1126/sciadv.aar8409. eCollection 2018 Jun.

12.

Macroscopic Evaluation of the Trimmed Frozen Block Is a Helpful Tool for Intraoperative Assessment of Resection Margins of Breast Cancer Specimens.

Trippel M, Slotta-Huspenina J, Becker K, Rau T, Paepke S, Maurer-Marti F, Langer R.

Int J Surg Pathol. 2018 Jun 1:1066896918780346. doi: 10.1177/1066896918780346. [Epub ahead of print]

PMID:
29953301
13.

Focal, remote-controlled, chronic chemical modulation of brain microstructures.

Ramadi KB, Dagdeviren C, Spencer KC, Joe P, Cotler M, Rousseau E, Nunez-Lopez C, Graybiel AM, Langer R, Cima MJ.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):7254-7259. doi: 10.1073/pnas.1804372115. Epub 2018 Jun 25.

PMID:
29941557
14.
15.

A specific expression profile of LC3B and p62 is associated with nonresponse to neoadjuvant chemotherapy in esophageal adenocarcinomas.

Adams O, Janser FA, Dislich B, Berezowska S, Humbert M, Seiler CA, Kroell D, Slotta-Huspenina J, Feith M, Ott K, Tschan MP, Langer R.

PLoS One. 2018 Jun 13;13(6):e0197610. doi: 10.1371/journal.pone.0197610. eCollection 2018.

16.

Harnessing single-cell genomics to improve the physiological fidelity of organoid-derived cell types.

Mead BE, Ordovas-Montanes J, Braun AP, Levy LE, Bhargava P, Szucs MJ, Ammendolia DA, MacMullan MA, Yin X, Hughes TK, Wadsworth MH 2nd, Ahmad R, Rakoff-Nahoum S, Carr SA, Langer R, Collins JJ, Shalek AK, Karp JM.

BMC Biol. 2018 Jun 5;16(1):62. doi: 10.1186/s12915-018-0527-2.

17.

Risk factors for esophageal cancer: emphasis on infectious agents.

El-Zimaity H, Di Pilato V, Novella Ringressi M, Brcic I, Rajendra S, Langer R, Dislich B, Tripathi M, Guindi M, Riddell R.

Ann N Y Acad Sci. 2018 May 31. doi: 10.1111/nyas.13858. [Epub ahead of print] Review.

PMID:
29851130
18.

An ingestible bacterial-electronic system to monitor gastrointestinal health.

Mimee M, Nadeau P, Hayward A, Carim S, Flanagan S, Jerger L, Collins J, McDonnell S, Swartwout R, Citorik RJ, Bulović V, Langer R, Traverso G, Chandrakasan AP, Lu TK.

Science. 2018 May 25;360(6391):915-918. doi: 10.1126/science.aas9315.

PMID:
29798884
19.

Lymphocytic esophagitis: an update on histologic diagnosis, endoscopic findings, and natural history.

Patil DT, Hammer S, Langer R, Yantiss RK.

Ann N Y Acad Sci. 2018 May 24. doi: 10.1111/nyas.13710. [Epub ahead of print] Review.

PMID:
29797752
20.

Stabilized single-injection inactivated polio vaccine elicits a strong neutralizing immune response.

Tzeng SY, McHugh KJ, Behrens AM, Rose S, Sugarman JL, Ferber S, Langer R, Jaklenec A.

Proc Natl Acad Sci U S A. 2018 Jun 5;115(23):E5269-E5278. doi: 10.1073/pnas.1720970115. Epub 2018 May 21.

21.

Correction to: MicroRNA expression profiling for the prediction of resistance to neoadjuvant radiochemotherapy in squamous cell carcinoma of the esophagus.

Slotta-Huspenina J, Drecoll E, Feith M, Habermehl D, Combs SE, Weichert W, Bettstetter M, Becker K, Langer R.

J Transl Med. 2018 May 16;16(1):128. doi: 10.1186/s12967-018-1513-8.

22.

A new anthraquinoid ligand for the iron-catalyzed hydrosilylation of carbonyl compounds at room temperature: new insights and kinetics.

Raya-Barón Á, Galdeano-Ruano CP, Oña-Burgos P, Rodríguez-Diéguez A, Langer R, López-Ruiz R, Romero-González R, Kuzu I, Fernández I.

Dalton Trans. 2018 May 29;47(21):7272-7281. doi: 10.1039/c8dt01123k.

PMID:
29766169
23.

Engineering a 3D-Bioprinted Model of Human Heart Valve Disease Using Nanoindentation-Based Biomechanics.

van der Valk DC, van der Ven CFT, Blaser MC, Grolman JM, Wu PJ, Fenton OS, Lee LH, Tibbitt MW, Andresen JL, Wen JR, Ha AH, Buffolo F, van Mil A, Bouten CVC, Body SC, Mooney DJ, Sluijter JPG, Aikawa M, Hjortnaes J, Langer R, Aikawa E.

Nanomaterials (Basel). 2018 May 3;8(5). pii: E296. doi: 10.3390/nano8050296.

24.

Advances in Biomaterials for Drug Delivery.

Fenton OS, Olafson KN, Pillai PS, Mitchell MJ, Langer R.

Adv Mater. 2018 May 7:e1705328. doi: 10.1002/adma.201705328. [Epub ahead of print] Review.

PMID:
29736981
25.

Evaporative Cooling Hydrogel Packaging for Storing Biologics Outside of the Cold Chain.

Ferber S, Behrens AM, McHugh KJ, Rosenberg EM, Linehan AR, Sugarman JL, Jayawardena HSN, Langer R, Jaklenec A.

Adv Healthc Mater. 2018 Jul;7(14):e1800220. doi: 10.1002/adhm.201800220. Epub 2018 May 7.

PMID:
29732715
26.

MicroRNA expression profiling for the prediction of resistance to neoadjuvant radiochemotherapy in squamous cell carcinoma of the esophagus.

Slotta-Huspenina J, Drecoll E, Feith M, Habermehl D, Combs S, Weichert W, Bettstetter M, Becker K, Langer R.

J Transl Med. 2018 Apr 25;16(1):109. doi: 10.1186/s12967-018-1492-9. Erratum in: J Transl Med. 2018 May 16;16(1):128.

27.

Controlling the Growth of Staphylococcus epidermidis by Layer-By-Layer Encapsulation.

Jonas AM, Glinel K, Behrens A, Anselmo AC, Langer RS, Jaklenec A.

ACS Appl Mater Interfaces. 2018 May 16;10(19):16250-16259. doi: 10.1021/acsami.8b01988. Epub 2018 May 3.

PMID:
29693369
28.

Corrigendum to "Applications of ethylene vinyl acetate copolymers (EVA) in drug delivery systems" [J. Control. Release 262(2017) 284-295].

Schneider C, Langer R, Loveday D, Hair D.

J Control Release. 2018 May 28;278:156-158. doi: 10.1016/j.jconrel.2018.04.007. No abstract available.

PMID:
29685764
29.

A fluorescence-based imaging approach to pharmacokinetic analysis of intracochlear drug delivery.

Ayoob AM, Peppi M, Tandon V, Langer R, Borenstein JT.

Hear Res. 2018 Apr 5. pii: S0378-5955(17)30640-8. doi: 10.1016/j.heares.2018.03.026. [Epub ahead of print]

PMID:
29661614
30.

Caffeine-catalyzed gels.

DiCiccio AM, Lee YL, Glettig DL, Walton ESE, de la Serna EL, Montgomery VA, Grant TM, Langer R, Traverso G.

Biomaterials. 2018 Jul;170:127-135. doi: 10.1016/j.biomaterials.2018.04.010. Epub 2018 Apr 6.

31.

Cancer-Germline Antigen Expression Discriminates Clinical Outcome to CTLA-4 Blockade.

Shukla SA, Bachireddy P, Schilling B, Galonska C, Zhan Q, Bango C, Langer R, Lee PC, Gusenleitner D, Keskin DB, Babadi M, Mohammad A, Gnirke A, Clement K, Cartun ZJ, Van Allen EM, Miao D, Huang Y, Snyder A, Merghoub T, Wolchok JD, Garraway LA, Meissner A, Weber JS, Hacohen N, Neuberg D, Potts PR, Murphy GF, Lian CG, Schadendorf D, Hodi FS, Wu CJ.

Cell. 2018 Apr 19;173(3):624-633.e8. doi: 10.1016/j.cell.2018.03.026. Epub 2018 Apr 12.

PMID:
29656892
32.

Accuracy of Bioelectrical Impedance Analysis in Estimated Longitudinal Fat-Free Mass Changes in Male Army Cadets.

Langer RD, Matias CN, Borges JH, Cirolini VX, Páscoa MA, Guerra-Júnior G, Gonçalves EM.

Mil Med. 2018 Jul 1;183(7-8):e324-e331. doi: 10.1093/milmed/usx223.

PMID:
29590470
33.

Surface tension-assisted additive manufacturing.

Ragelle H, Tibbitt MW, Wu SY, Castillo MA, Cheng GZ, Gangadharan SP, Anderson DG, Cima MJ, Langer R.

Nat Commun. 2018 Mar 22;9(1):1184. doi: 10.1038/s41467-018-03391-w.

34.

Application of the 8th edition of the AJCC yTNM staging system shows improved prognostication in a single center cohort of esophageal carcinomas.

Kröll D, Noser L, Erdem S, Storni F, Arnold D, Dislich B, Zlobec I, Candinas D, Seiler CA, Langer R.

Surg Oncol. 2018 Mar;27(1):100-105. doi: 10.1016/j.suronc.2017.12.005. Epub 2018 Jan 31.

PMID:
29549896
35.

Design and Synthesis of Waterborne Polyurethanes.

Kang SY, Ji Z, Tseng LF, Turner SA, Villanueva DA, Johnson R, Albano A, Langer R.

Adv Mater. 2018 May;30(18):e1706237. doi: 10.1002/adma.201706237. Epub 2018 Mar 15.

PMID:
29543353
36.

Defining Outcomes for β-cell Replacement Therapy in the Treatment of Diabetes: A Consensus Report on the Igls Criteria From the IPITA/EPITA Opinion Leaders Workshop.

Rickels MR, Stock PG, de Koning EJP, Piemonti L, Pratschke J, Alejandro R, Bellin MD, Berney T, Choudhary P, Johnson PR, Kandaswamy R, Kay TWH, Keymeulen B, Kudva YC, Latres E, Langer RM, Lehmann R, Ludwig B, Markmann JF, Marinac M, Odorico JS, Pattou F, Senior PA, Shaw JAM, Vantyghem MC, White S.

Transplantation. 2018 Sep;102(9):1479-1486. doi: 10.1097/TP.0000000000002158.

PMID:
29528967
37.

Convergence for Translation: Drug-Delivery Research in Multidisciplinary Teams.

Traverso G, Kirtane AR, Schoellhammer CM, Langer R.

Angew Chem Int Ed Engl. 2018 Apr 9;57(16):4156-4163. doi: 10.1002/anie.201712512. Epub 2018 Mar 9. Review.

PMID:
29520902
38.

Rapid, Single-Cell Analysis and Discovery of Vectored mRNA Transfection In Vivo with a loxP-Flanked tdTomato Reporter Mouse.

Kauffman KJ, Oberli MA, Dorkin JR, Hurtado JE, Kaczmarek JC, Bhadani S, Wyckoff J, Langer R, Jaklenec A, Anderson DG.

Mol Ther Nucleic Acids. 2018 Mar 2;10:55-63. doi: 10.1016/j.omtn.2017.11.005. Epub 2017 Nov 21.

39.

Biocompatible Semiconductor Quantum Dots as Cancer Imaging Agents.

McHugh KJ, Jing L, Behrens AM, Jayawardena S, Tang W, Gao M, Langer R, Jaklenec A.

Adv Mater. 2018 May;30(18):e1706356. doi: 10.1002/adma.201706356. Epub 2018 Feb 22. Review.

PMID:
29468747
40.

Carbodiphosphorane-based nickel pincer complexes and their (de)protonated analogues: dimerisation, ligand tautomers and proton affinities.

Maser L, Herritsch J, Langer R.

Dalton Trans. 2018 Aug 7;47(31):10544-10552. doi: 10.1039/c7dt04930g.

PMID:
29468238
41.

Defining outcomes for β-cell replacement therapy in the treatment of diabetes: a consensus report on the Igls criteria from the IPITA/EPITA opinion leaders workshop.

Rickels MR, Stock PG, de Koning EJP, Piemonti L, Pratschke J, Alejandro R, Bellin MD, Berney T, Choudhary P, Johnson PR, Kandaswamy R, Kay TWH, Keymeulen B, Kudva YC, Latres E, Langer RM, Lehmann R, Ludwig B, Markmann JF, Marinac M, Odorico JS, Pattou F, Senior PA, Shaw JAM, Vantyghem MC, White S.

Transpl Int. 2018 Apr;31(4):343-352. doi: 10.1111/tri.13138. Review.

PMID:
29453879
42.

Drug delivery across length scales.

Delcassian D, Patel AK, Cortinas AB, Langer R.

J Drug Target. 2018 Feb 20:1-15. doi: 10.1080/1061186X.2018.1438440. [Epub ahead of print]

PMID:
29415575
43.

PD-L1 and PD-1 and characterization of tumor-infiltrating lymphocytes in high grade sarcomas of soft tissue - prognostic implications and rationale for immunotherapy.

Boxberg M, Steiger K, Lenze U, Rechl H, von Eisenhart-Rothe R, Wörtler K, Weichert W, Langer R, Specht K.

Oncoimmunology. 2017 Nov 20;7(3):e1389366. doi: 10.1080/2162402X.2017.1389366. eCollection 2018.

PMID:
29399389
44.

Umpolung at Boron: Ancillary-Ligand-Induced Formation of Boron-Based Donor Ligands from Phosphine-Boranes.

Vondung L, Alig L, Ballmann M, Langer R.

Chemistry. 2018 Aug 22;24(47):12346-12353. doi: 10.1002/chem.201705847. Epub 2018 Mar 22.

PMID:
29389052
45.

Nanoparticles for Immune Cytokine TRAIL-Based Cancer Therapy.

Guimarães PPG, Gaglione S, Sewastianik T, Carrasco RD, Langer R, Mitchell MJ.

ACS Nano. 2018 Feb 27;12(2):912-931. doi: 10.1021/acsnano.7b05876. Epub 2018 Feb 6.

PMID:
29378114
46.

Partial DNA-guided Cas9 enables genome editing with reduced off-target activity.

Yin H, Song CQ, Suresh S, Kwan SY, Wu Q, Walsh S, Ding J, Bogorad RL, Zhu LJ, Wolfe SA, Koteliansky V, Xue W, Langer R, Anderson DG.

Nat Chem Biol. 2018 Mar;14(3):311-316. doi: 10.1038/nchembio.2559. Epub 2018 Jan 29.

47.

Miniaturized neural system for chronic, local intracerebral drug delivery.

Dagdeviren C, Ramadi KB, Joe P, Spencer K, Schwerdt HN, Shimazu H, Delcasso S, Amemori KI, Nunez-Lopez C, Graybiel AM, Cima MJ, Langer R.

Sci Transl Med. 2018 Jan 24;10(425). pii: eaan2742. doi: 10.1126/scitranslmed.aan2742.

PMID:
29367347
48.

Development of an oral once-weekly drug delivery system for HIV antiretroviral therapy.

Kirtane AR, Abouzid O, Minahan D, Bensel T, Hill AL, Selinger C, Bershteyn A, Craig M, Mo SS, Mazdiyasni H, Cleveland C, Rogner J, Lee YL, Booth L, Javid F, Wu SJ, Grant T, Bellinger AM, Nikolic B, Hayward A, Wood L, Eckhoff PA, Nowak MA, Langer R, Traverso G.

Nat Commun. 2018 Jan 9;9(1):2. doi: 10.1038/s41467-017-02294-6.

49.

Circulating Magnetic Microbubbles for Localized Real-Time Control of Drug Delivery by Ultrasonography-Guided Magnetic Targeting and Ultrasound.

Chertok B, Langer R.

Theranostics. 2018 Jan 1;8(2):341-357. doi: 10.7150/thno.20781. eCollection 2018.

50.

Erratum: Glucose-responsive insulin by molecular and physical design.

Bakh NA, Cortinas AB, Weiss MA, Langer RS, Anderson DG, Gu Z, Dutta S, Strano MS.

Nat Chem. 2017 Dec 19;10(1):109. doi: 10.1038/nchem.2898.

PMID:
29256502

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