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Proof-of-Concept Study of Drug Brain Permeability Between in Vivo Human Brain and an in Vitro iPSCs-Human Blood-Brain Barrier Model.

Roux GL, Jarray R, Guyot AC, Pavoni S, Costa N, Théodoro F, Nassor F, Pruvost A, Tournier N, Kiyan Y, Langer O, Yates F, Deslys JP, Mabondzo A.

Sci Rep. 2019 Nov 5;9(1):16310. doi: 10.1038/s41598-019-52213-6.


Pharmacokinetic imaging with radiolabeled molecularly targeted anticancer drugs.

Bauer M, Zeitlinger M, Langer O.

J Nucl Med. 2019 Oct 4. pii: jnumed.119.236174. doi: 10.2967/jnumed.119.236174. [Epub ahead of print] No abstract available.


Measurement of cerebral ABCC1 transport activity in wild-type and APP/PS1-21 mice with positron emission tomography.

Zoufal V, Mairinger S, Krohn M, Wanek T, Filip T, Sauberer M, Stanek J, Kuntner C, Pahnke J, Langer O.

J Cereb Blood Flow Metab. 2019 Jun 13:271678X19854541. doi: 10.1177/0271678X19854541. [Epub ahead of print]


Generation and Characterization of an Abcc1 Humanized Mouse Model (hABCC1flx/flx ) with Knockout Capability.

Krohn M, Zoufal V, Mairinger S, Wanek T, Paarmann K, Brüning T, Eiriz I, Brackhan M, Langer O, Pahnke J.

Mol Pharmacol. 2019 Aug;96(2):138-147. doi: 10.1124/mol.119.115824. Epub 2019 Jun 12.


Towards Improved Pharmacokinetic Models for the Analysis of Transporter-Mediated Hepatic Disposition of Drug Molecules with Positron Emission Tomography.

Hernández Lozano I, Karch R, Bauer M, Blaickner M, Matsuda A, Wulkersdorfer B, Hacker M, Zeitlinger M, Langer O.

AAPS J. 2019 Apr 29;21(4):61. doi: 10.1208/s12248-019-0323-0.


Imaging P-Glycoprotein Function at the Blood-Brain Barrier as a Determinant of the Variability in Response to Central Nervous System Drugs.

Bauer M, Tournier N, Langer O.

Clin Pharmacol Ther. 2019 May;105(5):1061-1064. doi: 10.1002/cpt.1402. Epub 2019 Mar 23. No abstract available.


PET imaging of the mouse brain reveals a dynamic regulation of SERT density in a chronic stress model.

Reisinger SN, Wanek T, Langer O, Pollak DD.

Transl Psychiatry. 2019 Feb 11;9(1):80. doi: 10.1038/s41398-019-0416-7.


Inhibition of ABCB1 and ABCG2 at the Mouse Blood-Brain Barrier with Marketed Drugs To Improve Brain Delivery of the Model ABCB1/ABCG2 Substrate [11C]erlotinib.

Traxl A, Mairinger S, Filip T, Sauberer M, Stanek J, Poschner S, Jäger W, Zoufal V, Novarino G, Tournier N, Bauer M, Wanek T, Langer O.

Mol Pharm. 2019 Mar 4;16(3):1282-1293. doi: 10.1021/acs.molpharmaceut.8b01217. Epub 2019 Feb 11.


Impact of P-Glycoprotein Function on the Brain Kinetics of the Weak Substrate 11C-Metoclopramide Assessed with PET Imaging in Humans.

Tournier N, Bauer M, Pichler V, Nics L, Klebermass EM, Bamminger K, Matzneller P, Weber M, Karch R, Caillé F, Auvity S, Marie S, Jäger W, Wadsak W, Hacker M, Zeitlinger M, Langer O.

J Nucl Med. 2019 Jul;60(7):985-991. doi: 10.2967/jnumed.118.219972. Epub 2019 Jan 10.


PET-MR and SPECT-MR multimodality probes: Development and challenges.

Yang CT, Ghosh KK, Padmanabhan P, Langer O, Liu J, Eng DNC, Halldin C, Gulyás B.

Theranostics. 2018 Nov 29;8(22):6210-6232. doi: 10.7150/thno.26610. eCollection 2018. Review.


Molar activity - The keystone in 11C-radiochemistry: An explorative study using the gas phase method.

Pichler V, Zenz T, Philippe C, Vraka C, Berrotéran-Infante N, Pfaff S, Nics L, Ozenil M, Langer O, Willeit M, Traub-Weidinger T, Lanzenberger R, Mitterhauser M, Hacker M, Wadsak W.

Nucl Med Biol. 2018 Dec;67:21-26. doi: 10.1016/j.nucmedbio.2018.09.003. Epub 2018 Oct 12.


EGFR is required for FOS-dependent bone tumor development via RSK2/CREB signaling.

Linder M, Glitzner E, Srivatsa S, Bakiri L, Matsuoka K, Shahrouzi P, Dumanic M, Novoszel P, Mohr T, Langer O, Wanek T, Mitterhauser M, Wagner EF, Sibilia M.

EMBO Mol Med. 2018 Nov;10(11). pii: e9408. doi: 10.15252/emmm.201809408.


Age dependency of cerebral P-glycoprotein function in wild-type and APPPS1 mice measured with PET.

Zoufal V, Wanek T, Krohn M, Mairinger S, Filip T, Sauberer M, Stanek J, Pekar T, Bauer M, Pahnke J, Langer O.

J Cereb Blood Flow Metab. 2018 Oct 24:271678X18806640. doi: 10.1177/0271678X18806640. [Epub ahead of print]


Humanization of the Blood-Brain Barrier Transporter ABCB1 in Mice Disrupts Genomic Locus - Lessons from Three Unsuccessful Approaches.

Krohn M, Wanek T, Menet MC, Noack A, Declèves X, Langer O, Löscher W, Pahnke J.

Eur J Microbiol Immunol (Bp). 2018 Jul 6;8(3):78-86. doi: 10.1556/1886.2018.00008. eCollection 2018 Sep 28.


Liver Imaging and Hepatobiliary Contrast Media.

Pastor CM, Langer O, Van Beers BE.

Contrast Media Mol Imaging. 2018 Sep 9;2018:2487405. doi: 10.1155/2018/2487405. eCollection 2018. No abstract available.


A Proof-of-Concept Study to Inhibit ABCG2- and ABCB1-Mediated Efflux Transport at the Human Blood-Brain Barrier.

Bauer M, Karch R, Wulkersdorfer B, Philippe C, Nics L, Klebermass EM, Weber M, Poschner S, Haslacher H, Jäger W, Tournier N, Wadsak W, Hacker M, Zeitlinger M, Langer O.

J Nucl Med. 2019 Apr;60(4):486-491. doi: 10.2967/jnumed.118.216432. Epub 2018 Sep 20.


Effect of Rifampicin on the Distribution of [11C]Erlotinib to the Liver, a Translational PET Study in Humans and in Mice.

Bauer M, Traxl A, Matsuda A, Karch R, Philippe C, Nics L, Klebermass EM, Wulkersdorfer B, Weber M, Poschner S, Tournier N, Jäger W, Wadsak W, Hacker M, Wanek T, Zeitlinger M, Langer O.

Mol Pharm. 2018 Oct 1;15(10):4589-4598. doi: 10.1021/acs.molpharmaceut.8b00588. Epub 2018 Sep 14.



Langer O.

Am J Obstet Gynecol. 2018 Dec;219(6):630. doi: 10.1016/j.ajog.2018.08.013. Epub 2018 Aug 16. No abstract available.


Impact of rifampicin-inhibitable transport on the liver distribution and tissue kinetics of erlotinib assessed with PET imaging in rats.

Amor D, Goutal S, Marie S, Caillé F, Bauer M, Langer O, Auvity S, Tournier N.

EJNMMI Res. 2018 Aug 16;8(1):81. doi: 10.1186/s13550-018-0434-0.


Influence of Multidrug Resistance-Associated Proteins on the Excretion of the ABCC1 Imaging Probe 6-Bromo-7-[11C]Methylpurine in Mice.

Zoufal V, Mairinger S, Krohn M, Wanek T, Filip T, Sauberer M, Stanek J, Traxl A, Schuetz JD, Kuntner C, Pahnke J, Langer O.

Mol Imaging Biol. 2019 Apr;21(2):306-316. doi: 10.1007/s11307-018-1230-y.


Comparison of fully-automated radiosyntheses of [11C]erlotinib for preclinical and clinical use starting from in target produced [11C]CO2 or [11C]CH4.

Philippe C, Mairinger S, Pichler V, Stanek J, Nics L, Mitterhauser M, Hacker M, Wanek T, Langer O, Wadsak W.

EJNMMI Radiopharm Chem. 2018;3(1):8. doi: 10.1186/s41181-018-0044-1. Epub 2018 May 30.


P-Glycoprotein (ABCB1) Inhibits the Influx and Increases the Efflux of 11C-Metoclopramide Across the Blood-Brain Barrier: A PET Study on Nonhuman Primates.

Auvity S, Caillé F, Marie S, Wimberley C, Bauer M, Langer O, Buvat I, Goutal S, Tournier N.

J Nucl Med. 2018 Oct;59(10):1609-1615. doi: 10.2967/jnumed.118.210104. Epub 2018 May 10.


Imaging techniques to study drug transporter function in vivo.

Tournier N, Stieger B, Langer O.

Pharmacol Ther. 2018 Sep;189:104-122. doi: 10.1016/j.pharmthera.2018.04.006. Epub 2018 Apr 22. Review.


Pharmacokinetics of the P-gp Inhibitor Tariquidar in Rats After Intravenous, Oral, and Intraperitoneal Administration.

Matzneller P, Kussmann M, Eberl S, Maier-Salamon A, Jäger W, Bauer M, Langer O, Zeitlinger M, Poeppl W.

Eur J Drug Metab Pharmacokinet. 2018 Oct;43(5):599-606. doi: 10.1007/s13318-018-0474-x.


Prevention of obesity and diabetes in pregnancy: is it an impossible dream?

Langer O.

Am J Obstet Gynecol. 2018 Jun;218(6):581-589. doi: 10.1016/j.ajog.2018.03.014. Epub 2018 Mar 23.


Pharmacological treatment of gestational diabetes mellitus: point/counterpoint.

Langer O.

Am J Obstet Gynecol. 2018 May;218(5):490-499. doi: 10.1016/j.ajog.2018.01.024. Epub 2018 Feb 28.


Abstracts of the 33rd International Austrian Winter Symposium : Zell am See, Austria. 24-27 January 2018.

Binzel K, Adelaja A, Wright CL, Scharre D, Zhang J, Knopp MV, Teoh EJ, Bottomley D, Scarsbrook A, Payne H, Afaq A, Bomanji J, van As N, Chua S, Hoskin P, Chambers A, Cook GJ, Warbey VS, Chau A, Ward P, Miller MP, Stevens DJ, Wilson L, Gleeson FV, Scheidhauer K, Seidl C, Autenrieth M, Bruchertseifer F, Apostolidis C, Kurtz F, Horn T, Pfob C, Schwaiger M, Gschwend J, D'Alessandria C, Morgenstern A, Uprimny C, Kroiss A, Decristoforo C, von Guggenberg E, Nilica B, Horninger W, Virgolini I, Rasul S, Poetsch N, Woehrer A, Preusser M, Mitterhauser M, Wadsak W, Widhalm G, Mischkulnig M, Hacker M, Traub-Weidinger T, Wright CL, Binzel K, Wuthrick EJ, Miller ED, Maniawski P, Zhang J, Knopp MV, Rep S, Hocevar M, Vaupotic J, Zdesar U, Zaletel K, Lezaic L, Mairinger S, Filip T, Sauberer M, Flunkert S, Wanek T, Stanek J, Okamura N, Langer O, Kuntner C, Fornito MC, Balzano R, Di Martino V, Cacciaguerra S, Russo G, Seifert D, Kleinova M, Cepa A, Ralis J, Hanc P, Lebeda O, Mosa M, Vandenberghe S, Mikhaylova E, Borys D, Viswanath V, Stockhoff M, Efthimiou N, Caribe P, Van Holen R, Karp JS, Binzel K, Zhang J, Wright CL, Maniawski P, Knopp MV, Haller PM, Farhan C, Piackova E, Jäger B, Knoll P, Kiss A, Podesser BK, Wojta J, Huber K, Mirzaei S, Traxl A, Komposch K, Glitzner E, Wanek T, Mairinger S, Sibilia M, Langer O, Fornito MC, Russello M, Russo G, Balzano R, Sorko S, Gallowitsch HJ, Kohlfuerst S, Matschnig S, Rieser M, Sorschag M, Lind P, Ležaič L, Rep S, Žibert J, Frelih N, Šuštar S, Binzel K, Adelaja A, Wright CL, Scharre D, Zhang J, Knopp MV, Baum RP, Langbein T, Singh A, Shahinfar M, Schuchardt C, Volk GF, Kulkarni HR, Fornito MC, Cacciaguerra S, Balzano R, Di Martino GV, Russo G, Thomson WH, Kudlacek M, Karik M, Farhan C, Rieger H, Pokieser W, Glaser K, Mirzaei S, Petz V, Tugendsam C, Buchinger W, Schmoll-Hauer B, Schenk IP, Rudolph K, Krebs M, Zettinig G, Zoufal V, Wanek T, Krohn M, Mairinger S, Stanek J, Sauberer M, Filip T, Pahnke J, Langer O, Weitzer F, Pernthaler B, Salamon S, Aigner R, Koranda P, Henzlová L, Kamínek M, Váchalová M, Bachleda P, Summer D, Garousi J, Oroujeni M, Mitran B, Andersson KG, Vorobyeva A, Löfblom JN, Orlova A, Tolmachev V, Decristoforo C, Kaeopookum P, Summer D, Orasch T, Lechner B, Petrik M, Novy Z, Rangger C, Haas H, Decristoforo C.

EJNMMI Res. 2018 Jan 23;8(Suppl 1):5. doi: 10.1186/s13550-017-0354-4. No abstract available.


Influence of breast cancer resistance protein and P-glycoprotein on tissue distribution and excretion of Ko143 assessed with PET imaging in mice.

Mairinger S, Zoufal V, Wanek T, Traxl A, Filip T, Sauberer M, Stanek J, Kuntner C, Pahnke J, Müller M, Langer O.

Eur J Pharm Sci. 2018 Mar 30;115:212-222. doi: 10.1016/j.ejps.2018.01.034. Epub 2018 Jan 31.


Intravenous infusion for the controlled exposure to the dual ABCB1 and ABCG2 inhibitor elacridar in nonhuman primates.

Goutal S, Langer O, Auvity S, Andrieux K, Coulon C, Caillé F, Gervais P, Cisternino S, Declèves X, Tournier N.

Drug Deliv Transl Res. 2018 Jun;8(3):536-542. doi: 10.1007/s13346-017-0472-6.


Influence of OATPs on Hepatic Disposition of Erlotinib Measured With Positron Emission Tomography.

Bauer M, Matsuda A, Wulkersdorfer B, Philippe C, Traxl A, Özvegy-Laczka C, Stanek J, Nics L, Klebermass EM, Poschner S, Jäger W, Patik I, Bakos É, Szakács G, Wadsak W, Hacker M, Zeitlinger M, Langer O.

Clin Pharmacol Ther. 2018 Jul;104(1):139-147. doi: 10.1002/cpt.888. Epub 2017 Nov 3.


Hepatocyte-Specific Deletion of EGFR in Mice Reduces Hepatic Abcg2 Transport Activity Measured by [11C]erlotinib and Positron Emission Tomography.

Traxl A, Komposch K, Glitzner E, Wanek T, Mairinger S, Langer O, Sibilia M.

Drug Metab Dispos. 2017 Oct;45(10):1093-1100. doi: 10.1124/dmd.117.077081. Epub 2017 Aug 8.


Reproducibility of Quantitative Brain Imaging Using a PET-Only and a Combined PET/MR System.

Lassen ML, Muzik O, Beyer T, Hacker M, Ladefoged CN, Cal-González J, Wadsak W, Rausch I, Langer O, Bauer M.

Front Neurosci. 2017 Jul 17;11:396. doi: 10.3389/fnins.2017.00396. eCollection 2017.


Expression of endogenous mouse APP modulates β-amyloid deposition in hAPP-transgenic mice.

Steffen J, Krohn M, Schwitlick C, Brüning T, Paarmann K, Pietrzik CU, Biverstål H, Jansone B, Langer O, Pahnke J.

Acta Neuropathol Commun. 2017 Jun 20;5(1):49. doi: 10.1186/s40478-017-0448-2.


[11C]Erlotinib PET cannot detect acquired erlotinib resistance in NSCLC tumor xenografts in mice.

Traxl A, Beikbaghban T, Wanek T, Kryeziu K, Pirker C, Mairinger S, Stanek J, Filip T, Sauberer M, Kuntner C, Berger W, Langer O.

Nucl Med Biol. 2017 Sep;52:7-15. doi: 10.1016/j.nucmedbio.2017.05.007. Epub 2017 May 25.


Effect of P-glycoprotein inhibition at the blood-brain barrier on brain distribution of (R)-[11 C]verapamil in elderly vs. young subjects.

Bauer M, Wulkersdorfer B, Karch R, Philippe C, Jäger W, Stanek J, Wadsak W, Hacker M, Zeitlinger M, Langer O.

Br J Clin Pharmacol. 2017 Sep;83(9):1991-1999. doi: 10.1111/bcp.13301. Epub 2017 May 4.


A Prediction Method for P-glycoprotein-Mediated Drug-Drug Interactions at the Human Blood-Brain Barrier From Blood Concentration-Time Profiles, Validated With PET Data.

Matsuda A, Karch R, Bauer M, Traxl A, Zeitlinger M, Langer O.

J Pharm Sci. 2017 Sep;106(9):2780-2786. doi: 10.1016/j.xphs.2017.03.024. Epub 2017 Apr 4.


On the applicability of [18F]FBPA to predict L-BPA concentration after amino acid preloading in HuH-7 liver tumor model and the implication for liver boron neutron capture therapy.

Grunewald C, Sauberer M, Filip T, Wanek T, Stanek J, Mairinger S, Rollet S, Kudejova P, Langer O, Schütz C, Blaickner M, Kuntner C.

Nucl Med Biol. 2017 Jan;44:83-89. doi: 10.1016/j.nucmedbio.2016.08.012. Epub 2016 Aug 29.


The History and Contributions of the Diabetes in Pregnancy Study Group of North America (1997-2015).

Rosen JA, Langer O, Reece EA, Miodovnik M.

Am J Perinatol. 2016 Nov;33(13):1223-1226. Epub 2016 Jul 11.


Assessment of P-Glycoprotein Transport Activity at the Human Blood-Retina Barrier with (R)-11C-Verapamil PET.

Bauer M, Karch R, Tournier N, Cisternino S, Wadsak W, Hacker M, Marhofer P, Zeitlinger M, Langer O.

J Nucl Med. 2017 Apr;58(4):678-681. doi: 10.2967/jnumed.116.182147. Epub 2016 Oct 13.


Preloading with L-BPA, L-tyrosine and L-DOPA enhances the uptake of [18F]FBPA in human and mouse tumour cell lines.

Wingelhofer B, Kreis K, Mairinger S, Muchitsch V, Stanek J, Wanek T, Langer O, Kuntner C.

Appl Radiat Isot. 2016 Dec;118:67-72. doi: 10.1016/j.apradiso.2016.08.026. Epub 2016 Sep 1.


Synthesis and preclinical characterization of 1-(6'-deoxy-6'-[18F]fluoro-β-d-allofuranosyl)-2-nitroimidazole (β-6'-[18F]FAZAL) as a positron emission tomography radiotracer to assess tumor hypoxia.

Wanek T, Kreis K, Križková P, Schweifer A, Denk C, Stanek J, Mairinger S, Filip T, Sauberer M, Edelhofer P, Traxl A, Muchitsch VE, Mereiter K, Hammerschmidt F, Cass CE, Damaraju VL, Langer O, Kuntner C.

Bioorg Med Chem. 2016 Nov 1;24(21):5326-5339. doi: 10.1016/j.bmc.2016.08.053. Epub 2016 Aug 29.


Strategies to Inhibit ABCB1- and ABCG2-Mediated Efflux Transport of Erlotinib at the Blood-Brain Barrier: A PET Study on Nonhuman Primates.

Tournier N, Goutal S, Auvity S, Traxl A, Mairinger S, Wanek T, Helal OB, Buvat I, Soussan M, Caillé F, Langer O.

J Nucl Med. 2017 Jan;58(1):117-122. doi: 10.2967/jnumed.116.178665. Epub 2016 Aug 4.


Use of PET Imaging to Evaluate Transporter-Mediated Drug-Drug Interactions.

Langer O.

J Clin Pharmacol. 2016 Jul;56 Suppl 7:S143-56. doi: 10.1002/jcph.722. Review.


32nd International Austrian Winter Symposium : Zell am See, the Netherlands. 20-23 January 2016.

Langsteger W, Rezaee A, Loidl W, Geinitz HS, Fitz F, Steinmair M, Broinger G, Pallwien-Prettner L, Beheshti M, Imamovic L, Beheshti M, Rendl G, Hackl D, Tsybrovsky O, Steinmair M, Emmanuel K, Moinfar F, Pirich C, Langsteger W, Bytyqi A, Karanikas G, Mayerhöfer M, Koperek O, Niederle B, Hartenbach M, Beyer T, Herrmann K, Czernin J, Rausch I, Rust P, DiFranco MD, Lassen M, Stadlbauer A, Mayerhöfer ME, Hartenbach M, Hacker M, Beyer T, Binzel K, Magnussen R, Wei W, Knopp MU, Flanigan DC, Kaeding C, Knopp MV, Leisser A, Nejabat M, Hartenbach M, Kramer G, Krainer M, Hacker M, Haug A, Lehnert W, Schmidt K, Kimiaei S, Bronzel M, Kluge A, Wright CL, Binzel K, Zhang J, Wuthrick E, Maniawski P, Knopp MV, Blaickner M, Rados E, Huber A, Dulovits M, Kulkarni H, Wiessalla S, Schuchardt C, Baum RP, Knäusl B, Georg D, Bauer M, Wulkersdorfer B, Wadsak W, Philippe C, Haslacher H, Zeitlinger M, Langer O, Bauer M, Feldmann M, Karch R, Wadsak W, Zeitlinger M, Koepp MJ, Asselin MC, Pataraia E, Langer O, Zeilinger M, Philippe C, Dumanic M, Pichler F, Pilz J, Hacker M, Wadsak W, Mitterhauser M, Nics L, Steiner B, Hacker M, Mitterhauser M, Wadsak W, Traxl A, Wanek T, Kryeziu K, Mairinger S, Stanek J, Berger W, Kuntner C, Langer O, Mairinger S, Wanek T, Traxl A, Krohn M, Stanek J, Filip T, Sauberer M, Kuntner C, Pahnke J, Langer O, Svatunek D, Denk C, Wilkovitsch M, Wanek T, Filip T, Kuntner-Hannes C, Fröhlich J, Mikula H, Denk C, Svatunek D, Wanek T, Mairinger S, Stanek J, Filip T, Fröhlich J, Mikula H, Kuntner-Hannes C, Balber T, Singer J, Fazekas J, Rami-Mark C, Berroterán-Infante N, Jensen-Jarolim E, Wadsak W, Hacker M, Viernstein H, Mitterhauser M, Denk C, Svatunek D, Sohr B, Mikula H, Fröhlich J, Wanek T, Kuntner-Hannes C, Filip T, Pfaff S, Philippe C, Mitterhauser M, Hartenbach M, Hacker M, Wadsak W, Wanek T, Halilbasic E, Visentin M, Mairinger S, Stieger B, Kuntner C, Trauner M, Langer O, Lam P, Aistleitner M, Eichinger R, Artner C, Eidherr H, Vraka C, Haug A, Mitterhauser M, Nics L, Hartenbach M, Hacker M, Wadsak W, Kvaternik H, Müller R, Hausberger D, Zink C, Aigner RM, Cossío U, Asensio M, Montes A, Akhtar S, Te Welscher Y, van Nostrum R, Gómez-Vallejo V, Llop J, VandeVyver F, Barclay T, Lippens N, Troch M, Hehenwarter L, Egger B, Holzmannhofer J, Rodrigues-Radischat M, Pirich C, Pötsch N, Rausch I, Wilhelm D, Weber M, Furtner J, Karanikas G, Wöhrer A, Mitterhauser M, Hacker M, Traub-Weidinger T, Cassou-Mounat T, Balogova S, Nataf V, Calzada M, Huchet V, Kerrou K, Devaux JY, Mohty M, Garderet L, Talbot JN, Stanzel S, Pregartner G, Schwarz T, Bjelic-Radisic V, Liegl-Atzwanger B, Aigner R, Stanzel S, Quehenberger F, Aigner RM, Marković AK, Janković M, Jerković VM, Paskaš M, Pupić G, Džodić R, Popović D, Fornito MC, Familiari D, Koranda P, Polzerová H, Metelková I, Henzlová L, Formánek R, Buriánková E, Kamínek M, Thomson WH, Lewis C, Thomson WH, O'Brien J, James G, Notghi A, Huber H, Stelzmüller I, Wunn R, Mandl M, Fellner F, Lamprecht B, Gabriel M, Fornito MC, Leonardi G, Thomson WH, O'Brien J, James G, Hudzietzová J, Sabol J, Fülöp M.

EJNMMI Res. 2016 Apr;6(Suppl 1):32. doi: 10.1186/s13550-016-0168-9. Epub 2016 Apr 18.


Whole-Body Distribution and Radiation Dosimetry of 11C-Elacridar and 11C-Tariquidar in Humans.

Bauer M, Blaickner M, Philippe C, Wadsak W, Hacker M, Zeitlinger M, Langer O.

J Nucl Med. 2016 Aug;57(8):1265-8. doi: 10.2967/jnumed.116.175182. Epub 2016 Apr 14.


Pilot PET Study to Assess the Functional Interplay Between ABCB1 and ABCG2 at the Human Blood-Brain Barrier.

Bauer M, Römermann K, Karch R, Wulkersdorfer B, Stanek J, Philippe C, Maier-Salamon A, Haslacher H, Jungbauer C, Wadsak W, Jäger W, Löscher W, Hacker M, Zeitlinger M, Langer O.

Clin Pharmacol Ther. 2016 Aug;100(2):131-41. doi: 10.1002/cpt.362. Epub 2016 May 9.


Generation and Characterization of a Breast Cancer Resistance Protein Humanized Mouse Model.

Dallas S, Salphati L, Gomez-Zepeda D, Wanek T, Chen L, Chu X, Kunta J, Mezler M, Menet MC, Chasseigneaux S, Declèves X, Langer O, Pierre E, DiLoreto K, Hoft C, Laplanche L, Pang J, Pereira T, Andonian C, Simic D, Rode A, Yabut J, Zhang X, Scheer N.

Mol Pharmacol. 2016 May;89(5):492-504. doi: 10.1124/mol.115.102079. Epub 2016 Feb 18.


Influence of 24-Nor-Ursodeoxycholic Acid on Hepatic Disposition of [(18)F]Ciprofloxacin, a Positron Emission Tomography Study in Mice.

Wanek T, Halilbasic E, Visentin M, Mairinger S, Römermann K, Stieger B, Kuntner C, Müller M, Langer O, Trauner M.

J Pharm Sci. 2016 Jan;105(1):106-12. doi: 10.1016/j.xphs.2015.11.014. Epub 2016 Jan 13.


Development and performance test of an online blood sampling system for determination of the arterial input function in rats.

Roehrbacher F, Bankstahl JP, Bankstahl M, Wanek T, Stanek J, Sauberer M, Muellauer J, Schroettner T, Langer O, Kuntner C.

EJNMMI Phys. 2015 Dec;2(1):1. doi: 10.1186/s40658-014-0106-8. Epub 2015 Jan 14.


Breast Cancer Resistance Protein and P-Glycoprotein Influence In Vivo Disposition of 11C-Erlotinib.

Traxl A, Wanek T, Mairinger S, Stanek J, Filip T, Sauberer M, Müller M, Kuntner C, Langer O.

J Nucl Med. 2015 Dec;56(12):1930-6. doi: 10.2967/jnumed.115.161273. Epub 2015 Sep 10.

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