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Items: 1 to 50 of 54

1.

Loss of human ICOSL results in combined immunodeficiency.

Roussel L, Landekic M, Golizeh M, Gavino C, Zhong MC, Chen J, Faubert D, Blanchet-Cohen A, Dansereau L, Parent MA, Marin S, Luo J, Le C, Ford BR, Langelier M, King IL, Divangahi M, Foulkes WD, Veillette A, Vinh DC.

J Exp Med. 2018 Dec 3;215(12):3151-3164. doi: 10.1084/jem.20180668.

PMID:
30498080
2.

PARP family enzymes: regulation and catalysis of the poly(ADP-ribose) posttranslational modification.

Langelier MF, Eisemann T, Riccio AA, Pascal JM.

Curr Opin Struct Biol. 2018 Nov 24;53:187-198. doi: 10.1016/j.sbi.2018.11.002. [Epub ahead of print] Review.

PMID:
30481609
3.

Pre-filled syringes for immunoglobulin G (IgG) replacement therapy: clinical experience from other disease settings.

Kafal AR, Vinh DC, Langelier MJ.

Expert Opin Drug Deliv. 2018 Nov 13. doi: 10.1080/17425247.2018.1546692. [Epub ahead of print]

PMID:
30422015
4.

Hydrofluoric Acid-Based Derivatization Strategy To Profile PARP-1 ADP-Ribosylation by LC-MS/MS.

Gagné JP, Langelier MF, Pascal JM, Poirier GG.

J Proteome Res. 2018 Jul 6;17(7):2542-2551. doi: 10.1021/acs.jproteome.8b00146. Epub 2018 Jun 11.

PMID:
29812941
5.

NAD+ analog reveals PARP-1 substrate-blocking mechanism and allosteric communication from catalytic center to DNA-binding domains.

Langelier MF, Zandarashvili L, Aguiar PM, Black BE, Pascal JM.

Nat Commun. 2018 Feb 27;9(1):844. doi: 10.1038/s41467-018-03234-8.

6.

The nucleosomal surface is the main target of histone ADP-ribosylation in response to DNA damage.

Karch KR, Langelier MF, Pascal JM, Garcia BA.

Mol Biosyst. 2017 Nov 21;13(12):2660-2671. doi: 10.1039/c7mb00498b.

7.

Novel bi-allelic splice mutations in CARD9 causing adult-onset Candida endophthalmitis.

Gavino C, Mellinghoff S, Cornely OA, Landekic M, Le C, Langelier M, Golizeh M, Proske S, Vinh DC.

Mycoses. 2018 Jan;61(1):61-65. doi: 10.1111/myc.12701. Epub 2017 Oct 17.

PMID:
28984994
8.

Unfolding of core nucleosomes by PARP-1 revealed by spFRET microscopy.

Sultanov DC, Gerasimova NS, Kudryashova KS, Maluchenko NV, Kotova EY, Langelier MF, Pascal JM, Kirpichnikov MP, Feofanov AV, Studitsky VM.

AIMS Genet. 2017;4(1):21-31. doi: 10.3934/genet.2017.1.21. Epub 2017 Jan 5.

9.

Purification of DNA Damage-Dependent PARPs from E. coli for Structural and Biochemical Analysis.

Langelier MF, Steffen JD, Riccio AA, McCauley M, Pascal JM.

Methods Mol Biol. 2017;1608:431-444. doi: 10.1007/978-1-4939-6993-7_27.

PMID:
28695525
10.

Morpholino-based correction of hypomorphic ZAP70 mutation in an adult with combined immunodeficiency.

Gavino C, Landekic M, Zeng J, Wu N, Jung S, Zhong MC, Cohen-Blanchet A, Langelier M, Neyret O, Lejtenyi D, Rochefort C, Cotton-Montpetit J, McCusker C, Mazer B, Veillette A, Vinh DC.

J Allergy Clin Immunol. 2017 May;139(5):1688-1692.e10. doi: 10.1016/j.jaci.2017.02.002. Epub 2017 Feb 17. No abstract available.

PMID:
28216435
11.

Expanded Scopes Of Practice For Dental Hygienists Associated With Improved Oral Health Outcomes For Adults.

Langelier M, Continelli T, Moore J, Baker B, Surdu S.

Health Aff (Millwood). 2016 Dec 1;35(12):2207-2215.

PMID:
27920308
12.

Tail and Kinase Modules Differently Regulate Core Mediator Recruitment and Function In Vivo.

Jeronimo C, Langelier MF, Bataille AR, Pascal JM, Pugh BF, Robert F.

Mol Cell. 2016 Nov 3;64(3):455-466. doi: 10.1016/j.molcel.2016.09.002. Epub 2016 Oct 20.

13.

Tankyrase-1 Ankyrin Repeats Form an Adaptable Binding Platform for Targets of ADP-Ribose Modification.

Eisemann T, McCauley M, Langelier MF, Gupta K, Roy S, Van Duyne GD, Pascal JM.

Structure. 2016 Oct 4;24(10):1679-1692. doi: 10.1016/j.str.2016.07.014. Epub 2016 Sep 1.

14.

Tankyrase Sterile α Motif Domain Polymerization Is Required for Its Role in Wnt Signaling.

Riccio AA, McCauley M, Langelier MF, Pascal JM.

Structure. 2016 Sep 6;24(9):1573-81. doi: 10.1016/j.str.2016.06.022. Epub 2016 Aug 4.

15.

A PARP1-ERK2 synergism is required for the induction of LTP.

Visochek L, Grigoryan G, Kalal A, Milshtein-Parush H, Gazit N, Slutsky I, Yeheskel A, Shainberg A, Castiel A, Seger R, Langelier MF, Dantzer F, Pascal JM, Segal M, Cohen-Armon M.

Sci Rep. 2016 Apr 28;6:24950. doi: 10.1038/srep24950.

16.

PARP-1 Activation Requires Local Unfolding of an Autoinhibitory Domain.

Dawicki-McKenna JM, Langelier MF, DeNizio JE, Riccio AA, Cao CD, Karch KR, McCauley M, Steffen JD, Black BE, Pascal JM.

Mol Cell. 2015 Dec 3;60(5):755-768. doi: 10.1016/j.molcel.2015.10.013. Epub 2015 Nov 25.

17.

Structural Basis of Detection and Signaling of DNA Single-Strand Breaks by Human PARP-1.

Eustermann S, Wu WF, Langelier MF, Yang JC, Easton LE, Riccio AA, Pascal JM, Neuhaus D.

Mol Cell. 2015 Dec 3;60(5):742-754. doi: 10.1016/j.molcel.2015.10.032. Epub 2015 Nov 25.

18.

Impaired RASGRF1/ERK-mediated GM-CSF response characterizes CARD9 deficiency in French-Canadians.

Gavino C, Hamel N, Zeng JB, Legault C, Guiot MC, Chankowsky J, Lejtenyi D, Lemire M, Alarie I, Dufresne S, Boursiquot JN, McIntosh F, Langelier M, Behr MA, Sheppard DC, Foulkes WD, Vinh DC.

J Allergy Clin Immunol. 2016 Apr;137(4):1178-1188.e7. doi: 10.1016/j.jaci.2015.09.016. Epub 2015 Oct 29.

PMID:
26521038
19.

Adoption of oral health curriculum by physician assistant education programs in 2014.

Langelier MH, Glicken AD, Surdu S.

J Physician Assist Educ. 2015 Jun;26(2):60-9. doi: 10.1097/JPA.0000000000000024.

PMID:
25933012
20.

Invasive Saccharomyces cerevisiae in a liver transplant patient: case report and review of infection in transplant recipients.

Popiel KY, Wong P, Lee MJ, Langelier M, Sheppard DC, Vinh DC.

Transpl Infect Dis. 2015 Jun;17(3):435-41. doi: 10.1111/tid.12384. Epub 2015 May 26. Review.

PMID:
25827213
21.

Quantitative site-specific ADP-ribosylation profiling of DNA-dependent PARPs.

Gagné JP, Ethier C, Defoy D, Bourassa S, Langelier MF, Riccio AA, Pascal JM, Moon KM, Foster LJ, Ning Z, Figeys D, Droit A, Poirier GG.

DNA Repair (Amst). 2015 Jun;30:68-79. doi: 10.1016/j.dnarep.2015.02.004. Epub 2015 Feb 19.

PMID:
25800440
22.

PARP-2 and PARP-3 are selectively activated by 5' phosphorylated DNA breaks through an allosteric regulatory mechanism shared with PARP-1.

Langelier MF, Riccio AA, Pascal JM.

Nucleic Acids Res. 2014 Jul;42(12):7762-75. doi: 10.1093/nar/gku474. Epub 2014 Jun 13.

23.

It is time to restructure health professions scope-of-practice regulations to remove barriers to care.

Dower C, Moore J, Langelier M.

Health Aff (Millwood). 2013 Nov;32(11):1971-6. doi: 10.1377/hlthaff.2013.0537.

PMID:
24191088
24.

Targeting PARP-1 allosteric regulation offers therapeutic potential against cancer.

Steffen JD, Tholey RM, Langelier MF, Planck JL, Schiewer MJ, Lal S, Bildzukewicz NA, Yeo CJ, Knudsen KE, Brody JR, Pascal JM.

Cancer Res. 2014 Jan 1;74(1):31-7. doi: 10.1158/0008-5472.CAN-13-1701. Epub 2013 Nov 4.

25.

Executive summary of the 2013 U.S. Veterinary Workforce Study.

Dall TM, Forte GJ, Storm MV, Gallo P, Langelier MH, Koory RM, Gillula JW.

J Am Vet Med Assoc. 2013 Jun 1;242(11):1507-14. doi: 10.2460/javma.242.11.1507. No abstract available.

PMID:
23683014
26.

Structural biology of the writers, readers, and erasers in mono- and poly(ADP-ribose) mediated signaling.

Karlberg T, Langelier MF, Pascal JM, Schüler H.

Mol Aspects Med. 2013 Dec;34(6):1088-108. doi: 10.1016/j.mam.2013.02.002. Epub 2013 Feb 28. Review.

27.

PARP-1 mechanism for coupling DNA damage detection to poly(ADP-ribose) synthesis.

Langelier MF, Pascal JM.

Curr Opin Struct Biol. 2013 Feb;23(1):134-43. doi: 10.1016/j.sbi.2013.01.003. Epub 2013 Jan 16. Review.

28.

Structural basis for DNA damage-dependent poly(ADP-ribosyl)ation by human PARP-1.

Langelier MF, Planck JL, Roy S, Pascal JM.

Science. 2012 May 11;336(6082):728-32. doi: 10.1126/science.1216338.

29.

Purification of human PARP-1 and PARP-1 domains from Escherichia coli for structural and biochemical analysis.

Langelier MF, Planck JL, Servent KM, Pascal JM.

Methods Mol Biol. 2011;780:209-26. doi: 10.1007/978-1-61779-270-0_13.

PMID:
21870263
30.

The RPB2 flap loop of human RNA polymerase II is dispensable for transcription initiation and elongation.

Palangat M, Grass JA, Langelier MF, Coulombe B, Landick R.

Mol Cell Biol. 2011 Aug;31(16):3312-25. doi: 10.1128/MCB.05318-11. Epub 2011 Jun 13.

31.

Crystal structures of poly(ADP-ribose) polymerase-1 (PARP-1) zinc fingers bound to DNA: structural and functional insights into DNA-dependent PARP-1 activity.

Langelier MF, Planck JL, Roy S, Pascal JM.

J Biol Chem. 2011 Mar 25;286(12):10690-701. doi: 10.1074/jbc.M110.202507. Epub 2011 Jan 13.

32.

The certified diabetes educator workforce in New York: findings from a statewide survey.

Langelier M, McGinnis S, Armstrong D, Zahn D.

Cah Sociol Demogr Med. 2010 Apr-Jun;50(2):155-77.

PMID:
20653218
33.

The Zn3 domain of human poly(ADP-ribose) polymerase-1 (PARP-1) functions in both DNA-dependent poly(ADP-ribose) synthesis activity and chromatin compaction.

Langelier MF, Ruhl DD, Planck JL, Kraus WL, Pascal JM.

J Biol Chem. 2010 Jun 11;285(24):18877-87. doi: 10.1074/jbc.M110.105668. Epub 2010 Apr 13.

34.

Workforce shortages in breast imaging: impact on mammography utilization.

Wing P, Langelier MH.

AJR Am J Roentgenol. 2009 Feb;192(2):370-8. doi: 10.2214/AJR.08.1665.

PMID:
19155396
35.

A third zinc-binding domain of human poly(ADP-ribose) polymerase-1 coordinates DNA-dependent enzyme activation.

Langelier MF, Servent KM, Rogers EE, Pascal JM.

J Biol Chem. 2008 Feb 15;283(7):4105-14. Epub 2007 Nov 30. Erratum in: J Biol Chem. 2008 Aug 15;283(33):22884.

36.

Nuclear medicine scientists: findings and recommendations based on a 2006 survey.

Wing P, Langelier MH, De AP.

J Nucl Med. 2007 Apr;48(4):11N-14N, 16N,19N-20N, 24N. No abstract available.

37.

Structural perspective on mutations affecting the function of multisubunit RNA polymerases.

Trinh V, Langelier MF, Archambault J, Coulombe B.

Microbiol Mol Biol Rev. 2006 Mar;70(1):12-36. Review.

38.

A Dental Hygiene Professional Practice Index (DHPPI) and access to oral health status and service use in the United States.

Wing P, Langelier MH, Continelli TA, Battrell A.

J Dent Hyg. 2005 Spring;79(2):10.

PMID:
16208778
39.

Functional dissection of the catalytic mechanism of mammalian RNA polymerase II.

Coulombe B, Langelier MF.

Biochem Cell Biol. 2005 Aug;83(4):497-504. Review.

40.

The highly conserved glutamic acid 791 of Rpb2 is involved in the binding of NTP and Mg(B) in the active center of human RNA polymerase II.

Langelier MF, Baali D, Trinh V, Greenblatt J, Archambault J, Coulombe B.

Nucleic Acids Res. 2005 May 10;33(8):2629-39. Print 2005.

41.

The changing professional practice of physician assistants: 1992 to 2000.

Wing P, Langelier MH, Salsberg ES, Hooker RS.

JAAPA. 2004 Jan;17(1):37-40, 42, 45-9.

PMID:
15307336
42.

RPAP1, a novel human RNA polymerase II-associated protein affinity purified with recombinant wild-type and mutated polymerase subunits.

Jeronimo C, Langelier MF, Zeghouf M, Cojocaru M, Bergeron D, Baali D, Forget D, Mnaimneh S, Davierwala AP, Pootoolal J, Chandy M, Canadien V, Beattie BK, Richards DP, Workman JL, Hughes TR, Greenblatt J, Coulombe B.

Mol Cell Biol. 2004 Aug;24(16):7043-58.

43.

The future of HIM.

Wing P, Langelier MH.

J AHIMA. 2004 Jun;75(6):28-32; quiz 33-4. No abstract available.

PMID:
15216704
44.

Interaction networks of the molecular machines that decode, replicate, and maintain the integrity of the human genome.

Coulombe B, Jeronimo C, Langelier MF, Cojocaru M, Bergeron D.

Mol Cell Proteomics. 2004 Sep;3(9):851-6. Epub 2004 Jun 22. Review.

45.
46.

Who we are. Findings from the 2002 member survey.

Wing P, Langelier M, Continelli T, Armstrong D.

J AHIMA. 2003 May;74(5):22-30; quiz 33-4. No abstract available.

PMID:
12747145
47.

[Focus on RNA polymerase II].

Langelier MF, Trinh V, Coulombe B.

Med Sci (Paris). 2002 Feb;18(2):210-216. Epub 2002 Feb 15. French. No abstract available.

48.

Structural and functional interactions of transcription factor (TF) IIA with TFIIE and TFIIF in transcription initiation by RNA polymerase II.

Langelier MF, Forget D, Rojas A, Porlier Y, Burton ZF, Coulombe B.

J Biol Chem. 2001 Oct 19;276(42):38652-7. Epub 2001 Aug 16.

49.
50.

Plasma lipoprotein profile and composition in White Carneau and Show Racer breeds of pigeons.

Langelier M, Connelly P, Subbiah MT.

Can J Biochem. 1976 Jan;54(1):27-31.

PMID:
175901

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