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Items: 30


A Metagenomic Comparison of Tracheal Aspirate and Mini-Bronchial Alveolar Lavage for Assessment of Respiratory Microbiota.

Kalantar KL, Moazed F, Christenson SC, Wilson J, Deiss T, Belzer A, Vessel K, Caldera S, Jauregui A, Bolourchi S, DeRisi JL, Calfee CS, Langelier C.

Am J Physiol Lung Cell Mol Physiol. 2019 Jan 17. doi: 10.1152/ajplung.00476.2018. [Epub ahead of print]


Integrating host response and unbiased microbe detection for lower respiratory tract infection diagnosis in critically ill adults.

Langelier C, Kalantar KL, Moazed F, Wilson MR, Crawford ED, Deiss T, Belzer A, Bolourchi S, Caldera S, Fung M, Jauregui A, Malcolm K, Lyden A, Khan L, Vessel K, Quan J, Zinter M, Chiu CY, Chow ED, Wilson J, Miller S, Matthay MA, Pollard KS, Christenson S, Calfee CS, DeRisi JL.

Proc Natl Acad Sci U S A. 2018 Dec 26;115(52):E12353-E12362. doi: 10.1073/pnas.1809700115. Epub 2018 Nov 27.


Pulmonary Metagenomic Sequencing Suggests Missed Infections in Immunocompromised Children.

Zinter MS, Dvorak CC, Mayday MY, Iwanaga K, Ly NP, McGarry ME, Church GD, Faricy LE, Rowan CM, Hume JR, Steiner ME, Crawford ED, Langelier C, Kalantar K, Chow ED, Miller S, Shimano K, Melton A, Yanik GA, Sapru A, DeRisi JL.

Clin Infect Dis. 2018 Sep 15. doi: 10.1093/cid/ciy802. [Epub ahead of print]


Chronic Meningitis Investigated via Metagenomic Next-Generation Sequencing.

Wilson MR, O'Donovan BD, Gelfand JM, Sample HA, Chow FC, Betjemann JP, Shah MP, Richie MB, Gorman MP, Hajj-Ali RA, Calabrese LH, Zorn KC, Chow ED, Greenlee JE, Blum JH, Green G, Khan LM, Banerji D, Langelier C, Bryson-Cahn C, Harrington W, Lingappa JR, Shanbhag NM, Green AJ, Brew BJ, Soldatos A, Strnad L, Doernberg SB, Jay CA, Douglas V, Josephson SA, DeRisi JL.

JAMA Neurol. 2018 Aug 1;75(8):947-955. doi: 10.1001/jamaneurol.2018.0463.


Malaria and the Microbiome: A Systematic Review.

Ippolito MM, Denny JE, Langelier C, Sears CL, Schmidt NW.

Clin Infect Dis. 2018 Nov 28;67(12):1831-1839. doi: 10.1093/cid/ciy374.


Breakthrough Invasive Fungal Infections on Isavuconazole Prophylaxis and Treatment: What Is Happening in the Real-World Setting?

Fung M, Schwartz BS, Doernberg SB, Langelier C, Lo M, Graff L, Tan M, Logan AC, Chin-Hong P, Babik JM.

Clin Infect Dis. 2018 Sep 14;67(7):1142-1143. doi: 10.1093/cid/ciy260. No abstract available.


Transcriptomic profiling reveals gene expression kinetics in patients with hypoxia and high altitude pulmonary edema.

Yuhong L, Tana W, Zhengzhong B, Feng T, Qin G, Yingzhong Y, Wei G, Yaping W, Langelier C, Rondina MT, Ge RL.

Gene. 2018 Apr 20;651:200-205. doi: 10.1016/j.gene.2018.01.052. Epub 2018 Jan 31.


Complete Genome Sequence of a Divergent Human Rhinovirus C Isolate from an Infant with Severe Community-Acquired Pneumonia in Colorado, USA.

Langelier C, White CV, Sontag MK, Mourani PM, DeRisi JL.

Genome Announc. 2017 Nov 30;5(48). pii: e01245-17. doi: 10.1128/genomeA.01245-17.


IFN-stimulated Gene Expression, Type 2 Inflammation, and Endoplasmic Reticulum Stress in Asthma.

Bhakta NR, Christenson SA, Nerella S, Solberg OD, Nguyen CP, Choy DF, Jung KL, Garudadri S, Bonser LR, Pollack JL, Zlock LT, Erle DJ, Langelier C, Derisi JL, Arron JR, Fahy JV, Woodruff PG.

Am J Respir Crit Care Med. 2018 Feb 1;197(3):313-324. doi: 10.1164/rccm.201706-1070OC.


Lung Microbiota Is Related to Smoking Status and to Development of Acute Respiratory Distress Syndrome in Critically Ill Trauma Patients.

Panzer AR, Lynch SV, Langelier C, Christie JD, McCauley K, Nelson M, Cheung CK, Benowitz NL, Cohen MJ, Calfee CS.

Am J Respir Crit Care Med. 2018 Mar 1;197(5):621-631. doi: 10.1164/rccm.201702-0441OC.


Metagenomic Sequencing Detects Respiratory Pathogens in Hematopoietic Cellular Transplant Patients.

Langelier C, Zinter MS, Kalantar K, Yanik GA, Christenson S, O'Donovan B, White C, Wilson M, Sapru A, Dvorak CC, Miller S, Chiu CY, DeRisi JL.

Am J Respir Crit Care Med. 2018 Feb 15;197(4):524-528. doi: 10.1164/rccm.201706-1097LE. No abstract available.


Use of isavuconazole in a patient with voriconazole-induced QTc prolongation.

Trang TP, Hanretty AM, Langelier C, Yang K.

Transpl Infect Dis. 2017 Aug;19(4). doi: 10.1111/tid.12712. Epub 2017 Jun 20.


Assessing biosynthetic potential of agricultural groundwater through metagenomic sequencing: A diverse anammox community dominates nitrate-rich groundwater.

Ludington WB, Seher TD, Applegate O, Li X, Kliegman JI, Langelier C, Atwill ER, Harter T, DeRisi JL.

PLoS One. 2017 Apr 6;12(4):e0174930. doi: 10.1371/journal.pone.0174930. eCollection 2017.


Antimicrobial Resistance: A Call to Action!

Brown L, Langelier C, Reid MJ, Rutishauser RL, Strnad L.

Clin Infect Dis. 2017 Jan 1;64(1):106-107. Epub 2016 Oct 6. No abstract available.


Raccoon Roundworm Infection Associated with Central Nervous System Disease and Ocular Disease - Six States, 2013-2015.

Sircar AD, Abanyie F, Blumberg D, Chin-Hong P, Coulter KS, Cunningham D, Huskins WC, Langelier C, Reid M, Scott BJ, Shirley DA, Babik JM, Belova A, Sapp SG, McAuliffe I, Rivera HN, Yabsley MJ, Montgomery SP.

MMWR Morb Mortal Wkly Rep. 2016 Sep 9;65(35):930-3. doi: 10.15585/mmwr.mm6535a2.


Baylisascaris procyonis-Associated Meningoencephalitis in a Previously Healthy Adult, California, USA.

Langelier C, Reid MJ, Halabi C, Witek N, LaRiviere A, Shah M, Wilson MR, Chin-Hong P, Douglas V, Kazacos KR, Babik JM.

Emerg Infect Dis. 2016 Aug;22(8):1480-4. doi: 10.3201/eid2208.151939.


Monocyte polarization in children with falciparum malaria: relationship to nitric oxide insufficiency and disease severity.

Weinberg JB, Volkheimer AD, Rubach MP, Florence SM, Mukemba JP, Kalingonji AR, Langelier C, Chen Y, Bush M, Yeo TW, Granger DL, Anstey NM, Mwaikambo ED.

Sci Rep. 2016 Jul 7;6:29151. doi: 10.1038/srep29151.


An Expression of Clinical Significance: Exploring the Human Genome to Understand the Variable Response to Rhinovirus.

Langelier C, Christenson SA.

Am J Respir Crit Care Med. 2016 Apr 1;193(7):710-2. doi: 10.1164/rccm.201511-2272ED. No abstract available.


Two Rapidly Growing Mycobacterial Species Isolated from a Brain Abscess: First Whole-Genome Sequences of Mycobacterium immunogenum and Mycobacterium llatzerense.

Greninger AL, Langelier C, Cunningham G, Keh C, Melgar M, Chiu CY, Miller S.

J Clin Microbiol. 2015 Jul;53(7):2374-7. doi: 10.1128/JCM.00402-15. Epub 2015 Apr 29.


Beyond the superficial: Coccidioides immitis fungaemia in a man with fever, fatigue and skin nodules: a case of an emerging and evolving pathogen.

Langelier C, Baxi SM, Iribarne D, Chin-Hong P.

BMJ Case Rep. 2014 Sep 16;2014. pii: bcr2014205333. doi: 10.1136/bcr-2014-205333.


Clinical, genomic, and metagenomic characterization of oral tongue squamous cell carcinoma in patients who do not smoke.

Li R, Faden DL, Fakhry C, Langelier C, Jiao Y, Wang Y, Wilkerson MD, Pedamallu CS, Old M, Lang J, Loyo M, Ahn SM, Tan M, Gooi Z, Chan J, Richmon J, Wood LD, Hruban RH, Bishop J, Westra WH, Chung CH, Califano J, Gourin CG, Bettegowda C, Meyerson M, Papadopoulos N, Kinzler KW, Vogelstein B, DeRisi JL, Koch WM, Agrawal N.

Head Neck. 2015 Nov;37(11):1642-9. doi: 10.1002/hed.23807. Epub 2014 Aug 23.


Think global, act local: chronic dysuria and sterile pyuria in an Eritrean-American woman.

Rutishauser RL, Langelier C, Baxi SM, Hanks D, Chin-Hong P.

BMJ Case Rep. 2014 Feb 11;2014. pii: bcr2013201546. doi: 10.1136/bcr-2013-201546.


Discovery of novel small-molecule HIV-1 replication inhibitors that stabilize capsid complexes.

Lamorte L, Titolo S, Lemke CT, Goudreau N, Mercier JF, Wardrop E, Shah VB, von Schwedler UK, Langelier C, Banik SS, Aiken C, Sundquist WI, Mason SW.

Antimicrob Agents Chemother. 2013 Oct;57(10):4622-31. doi: 10.1128/AAC.00985-13. Epub 2013 Jul 1.


Structural basis for ESCRT-III protein autoinhibition.

Bajorek M, Schubert HL, McCullough J, Langelier C, Eckert DM, Stubblefield WM, Uter NT, Myszka DG, Hill CP, Sundquist WI.

Nat Struct Mol Biol. 2009 Jul;16(7):754-62. doi: 10.1038/nsmb.1621. Epub 2009 Jun 14.


Biochemical characterization of a recombinant TRIM5alpha protein that restricts human immunodeficiency virus type 1 replication.

Langelier CR, Sandrin V, Eckert DM, Christensen DE, Chandrasekaran V, Alam SL, Aiken C, Olsen JC, Kar AK, Sodroski JG, Sundquist WI.

J Virol. 2008 Dec;82(23):11682-94. doi: 10.1128/JVI.01562-08. Epub 2008 Sep 17.


The molecular mechanism of hepcidin-mediated ferroportin down-regulation.

De Domenico I, Ward DM, Langelier C, Vaughn MB, Nemeth E, Sundquist WI, Ganz T, Musci G, Kaplan J.

Mol Biol Cell. 2007 Jul;18(7):2569-78. Epub 2007 May 2.


Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain.

Alam SL, Langelier C, Whitby FG, Koirala S, Robinson H, Hill CP, Sundquist WI.

Nat Struct Mol Biol. 2006 Nov;13(11):1029-30. Epub 2006 Oct 22.


Human ESCRT-II complex and its role in human immunodeficiency virus type 1 release.

Langelier C, von Schwedler UK, Fisher RD, De Domenico I, White PL, Hill CP, Kaplan J, Ward D, Sundquist WI.

J Virol. 2006 Oct;80(19):9465-80.


Inflammatory cytokines and cell death in BEAS-2B lung cells treated with soil dust, lipopolysaccharide, and surface-modified particles.

Veranth JM, Reilly CA, Veranth MM, Moss TA, Langelier CR, Lanza DL, Yost GS.

Toxicol Sci. 2004 Nov;82(1):88-96. Epub 2004 Aug 13.


Recognition of the nonpolar base 4-methylindole in DNA by the DNA repair adenine glycosylase MutY.

Chepanoske CL, Langelier CR, Chmiel NH, David SS.

Org Lett. 2000 May 4;2(9):1341-4.


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