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Items: 1 to 50 of 173

1.

FALDI-based criterion for and the origin of an electron density bridge with an associated (3,-1) critical point on Bader's molecular graph.

de Lange JH, van Niekerk DME, Cukrowski I.

J Comput Chem. 2018 Oct 15;39(27):2283-2299. doi: 10.1002/jcc.25548. Epub 2018 Oct 14.

PMID:
30318597
2.

Comment on: Early clinical manifestations of vibrio necrotising fasciitis.

Lange JH, Cegolon L.

Singapore Med J. 2018 Aug;59(8):449. doi: 10.11622/smedj.2018098. No abstract available.

3.

Exact and exclusive electron localization indices within QTAIM atomic basins.

de Lange JH, Cukrowski I.

J Comput Chem. 2018 Jul 30;39(20):1517-1530. doi: 10.1002/jcc.25223. Epub 2018 Apr 10.

PMID:
29635755
4.

Comment on: Definitive tests for dengue fever: when and which should I use?

Cegolon L, Heymann WC, Lange JH.

Singapore Med J. 2018 Mar;59(3):165. doi: 10.11622/smedj.2018031. No abstract available.

5.

FALDI-based decomposition of an atomic interaction line leads to 3D representation of the multicenter nature of interactions.

de Lange JH, van Niekerk DME, Cukrowski I.

J Comput Chem. 2018 Jun 15;39(16):973-985. doi: 10.1002/jcc.25175. Epub 2018 Feb 5.

PMID:
29399814
6.

Spiro-1-benzofuranpiperidinylalkanoic acids as a novel and selective sphingosine S1P5 receptor agonist chemotype.

Stoit AR, Lange JHM, Coolen HKAC, Rensink A, van den Hoogenband A, den Hartog AP, van Schaik S, Kruse CG.

Bioorg Med Chem Lett. 2018 Feb 1;28(3):459-465. doi: 10.1016/j.bmcl.2017.12.018. Epub 2017 Dec 9.

PMID:
29254642
7.

Travel health education.

Cegolon L, Heymann WC, Lange JH, Xodo C.

J Travel Med. 2017 Sep 1;24(5). doi: 10.1093/jtm/tax039. No abstract available.

PMID:
28931131
8.

Improving Italian general practice training: the role of academia.

Cegolon L, Heymann WC, Lange JH, Xodo C.

BJGP Open. 2017 Jun 14;1(2):bjgpopen17X100989. doi: 10.3399/bjgpopen17X100989. No abstract available.

9.

Gold(I) Hydrides as Proton Acceptors in Dihydrogen Bond Formation.

Cukrowski I, de Lange JH, Groenewald F, Raubenheimer HG.

Chemphyschem. 2017 Aug 18;18(16):2288-2294. doi: 10.1002/cphc.201700383. Epub 2017 Jul 6.

PMID:
28544420
10.

Comment on: Glioblastoma multiforme outcomes of 107 patients treated in two local institutions.

Lange JH.

Singapore Med J. 2017 Apr;58(4):227-228. doi: 10.11622/smedj.2017031. No abstract available.

11.

Training in Occupational Medicine: Jurisprudential Malfunctions in the Italian System and European Perspectives.

Cegolon L, Heymann WC, Xodo C, Lange JH.

Ann Ig. 2017 May-Jun;29(3):197-205. doi: 10.7416/ai.2017.2147.

12.

Climate change, emerging infections and blood donations.

Cegolon L, Heymann WC, Lange JH.

J Travel Med. 2017 May 1;24(3). doi: 10.1093/jtm/taw098. No abstract available.

PMID:
28355622
13.
14.

Comment on: Zika in Singapore: insights from One Health and social medicine.

Lange JH, Cegolon L.

Singapore Med J. 2017 Feb;58(2):113. doi: 10.11622/smedj.2017010. No abstract available.

15.
16.

The selective 5-HT6 receptor antagonist SLV has putative cognitive- and social interaction enhancing properties in rodent models of cognitive impairment.

de Bruin NMWJ, van Loevezijn A, Wicke KM, de Haan M, Venhorst J, Lange JHM, de Groote L, van der Neut MAW, Prickaerts J, Andriambeloson E, Foley AG, van Drimmelen M, van der Wetering M, Kruse CG.

Neurobiol Learn Mem. 2016 Sep;133:100-117. doi: 10.1016/j.nlm.2016.06.020. Epub 2016 Jun 21.

PMID:
27344942
17.

Optimization of N'-(arylsulfonyl)pyrazoline-1-carboxamidines by exploiting a novel interaction site in the 5-HT6 antagonistic binding pocket.

van Loevezijn A, Venhorst J, Iwema Bakker WI, Lange JHM, de Looff W, Henzen R, de Vries J, van de Woestijne RP, den Hartog AP, Verhoog S, van der Neut MAW, de Bruin NMWJ, Kruse CG.

Bioorg Med Chem Lett. 2016 Mar 15;26(6):1605-1611. doi: 10.1016/j.bmcl.2016.02.001. Epub 2016 Feb 2.

PMID:
26876931
18.

Comment on: Vitamin D deficiency.

Lange JH, Cegolon L.

Singapore Med J. 2015 Oct;56(10):588. doi: 10.11622/smedj.2015156. No abstract available.

19.

Non-asbestos Causes of mesothelioma and translocation of asbestos fibres.

Lange JH, Cegolon L.

Singapore Med J. 2015 Jun;56(6):361. doi: 10.11622/smedj.2015100. No abstract available.

20.

Comment on: cerebrovascular ischaemia after carbon monoxide intoxication.

Lange JH, Cegolon L.

Singapore Med J. 2015 Mar;56(3):175. No abstract available.

21.

Allosteric inhibition of the neuropeptidase neurolysin.

Hines CS, Ray K, Schmidt JJ, Xiong F, Feenstra RW, Pras-Raves M, de Moes JP, Lange JH, Melikishvili M, Fried MG, Mortenson P, Charlton M, Patel Y, Courtney SM, Kruse CG, Rodgers DW.

J Biol Chem. 2014 Dec 19;289(51):35605-19. doi: 10.1074/jbc.M114.620930. Epub 2014 Nov 5.

22.

Other causative factors for lung diseases in populations exposed to asbestos.

Lange JH, Heymann WC, Cegolon L.

Clin Respir J. 2014 Apr;8(2):253-4. doi: 10.1111/crj.12069. Epub 2014 Jan 20. No abstract available.

PMID:
24438458
24.

A laboratory investigation to assess the influence of cement augmentation of screw and plate fixation in a simulation of distal femoral fracture of osteoporotic and non-osteoporotic bone.

Wähnert D, Lange JH, Schulze M, Gehweiler D, Kösters C, Raschke MJ.

Bone Joint J. 2013 Oct;95-B(10):1406-9. doi: 10.1302/0301-620X.95B10.31220.

PMID:
24078541
25.

Jellyfish stings and their management: a review.

Cegolon L, Heymann WC, Lange JH, Mastrangelo G.

Mar Drugs. 2013 Feb 22;11(2):523-50. doi: 10.3390/md11020523. Review.

26.

Toward an AIDS-free generation with option B+: reconceptualizing and integrating prevention of mother to child transmission (PMTCT) with pediatric antiretroviral therapy initiatives.

Thyssen A, Lange JH, Thyssen E, Reddi A.

J Acquir Immune Defic Syndr. 2013 Feb 1;62(2):127-8. doi: 10.1097/QAI.0b013e3182749994. No abstract available.

PMID:
23018370
27.

The potential of implant augmentation in the treatment of osteoporotic distal femur fractures: a biomechanical study.

Wähnert D, Lange JH, Schulze M, Lenschow S, Stange R, Raschke MJ.

Injury. 2013 Jun;44(6):808-12. doi: 10.1016/j.injury.2012.08.053. Epub 2012 Sep 20.

PMID:
23000049
28.

Human capital contracts for global health: a plan to increase the number of physicians in resource limited settings.

Reddi A, Thyssen A, Smith D, Lange JH, Akileswaran C.

AIDS. 2012 Sep 24;26(15):1979-80. doi: 10.1097/QAD.0b013e32835857d4. No abstract available.

PMID:
22992581
29.

Infectious disease risk in asbestos abatement workers.

Lange JH, Mastrangelo G, Cegolon L.

BMC Public Health. 2012 Aug 16;12:665. doi: 10.1186/1471-2458-12-665.

30.

Lung cancer risk in subjects exposed to organic dust: an unexpected and surprising story.

Mastrangelo G, Rylander R, Cegolon L, Lange JH.

Thorax. 2012 Dec;67(12):1112; author reply 1112-3. doi: 10.1136/thoraxjnl-2011-201279. Epub 2012 Jan 10. No abstract available.

PMID:
22234726
31.

Novel indole and azaindole (pyrrolopyridine) cannabinoid (CB) receptor agonists: design, synthesis, structure-activity relationships, physicochemical properties and biological activity.

Blaazer AR, Lange JH, van der Neut MA, Mulder A, den Boon FS, Werkman TR, Kruse CG, Wadman WJ.

Eur J Med Chem. 2011 Oct;46(10):5086-98. doi: 10.1016/j.ejmech.2011.08.021. Epub 2011 Aug 23.

PMID:
21885167
32.

Biophysical and physicochemical methods differentiate highly ligand-efficient human D-amino acid oxidase inhibitors.

Lange JH, Venhorst J, van Dongen MJ, Frankena J, Bassissi F, de Bruin NM, den Besten C, de Beer SB, Oostenbrink C, Markova N, Kruse CG.

Eur J Med Chem. 2011 Oct;46(10):4808-19. doi: 10.1016/j.ejmech.2011.04.023. Epub 2011 May 13.

PMID:
21880399
33.

A proposed threshold exposure for airborne asbestos.

Lange JH, Mastrangelo G, Cegolon L.

Occup Environ Med. 2012 Mar;69(3):227-8. doi: 10.1136/oemed-2011-100225. Epub 2011 Aug 17. No abstract available.

PMID:
21849346
34.

Osteopontin, asbestos exposure and pleural plaques: a cross-sectional study.

Mastrangelo G, Marangi G, Ballarin MN, Michilin S, Fabricio AS, Valentini F, Lange JH, Fedeli U, Cegolon L, Gion M.

BMC Public Health. 2011 Apr 8;11:220. doi: 10.1186/1471-2458-11-220.

35.

SLV330, a cannabinoid CB(1) receptor antagonist, attenuates ethanol and nicotine seeking and improves inhibitory response control in rats.

de Bruin NM, Lange JH, Kruse CG, Herremans AH, Schoffelmeer AN, van Drimmelen M, De Vries TJ.

Behav Brain Res. 2011 Mar 1;217(2):408-15. doi: 10.1016/j.bbr.2010.11.013. Epub 2010 Nov 11.

PMID:
21074574
36.

The evaluation of a health education campaign on the use of leave from work during pregnancy.

Mastrangelo G, Lange JH, Fadda E, Agostini O, Agnesi R, Bardin A, Cegolon L.

BMC Public Health. 2010 Nov 12;10:694. doi: 10.1186/1471-2458-10-694.

37.

Two distinct classes of novel pyrazolinecarboxamides as potent cannabinoid CB1 receptor agonists.

Lange JH, Attali A, van der Neut MA, Wals HC, Mulder A, Zilaout H, Duursma A, van Aken HH, van Vliet BJ.

Bioorg Med Chem Lett. 2010 Sep 1;20(17):4992-8. doi: 10.1016/j.bmcl.2010.07.056. Epub 2010 Jul 17.

PMID:
20688519
38.

The Primary Care Practitioner and the diagnosis of occupational diseases.

Cegolon L, Lange JH, Mastrangelo G.

BMC Public Health. 2010 Jul 9;10:405. doi: 10.1186/1471-2458-10-405.

39.

Probing the cannabinoid CB1/CB2 receptor subtype selectivity limits of 1,2-diarylimidazole-4-carboxamides by fine-tuning their 5-substitution pattern.

Lange JH, van der Neut MA, Borst AJ, Yildirim M, van Stuivenberg HH, van Vliet BJ, Kruse CG.

Bioorg Med Chem Lett. 2010 May 1;20(9):2770-5. doi: 10.1016/j.bmcl.2010.03.068. Epub 2010 Mar 19.

PMID:
20363132
40.

Swine flu and respiratory protection.

Lange JH, Cegolon L, Mastrangelo G.

Singapore Med J. 2010 Feb;51(2):180-1. No abstract available.

41.

Synthesis, SAR and intramolecular hydrogen bonding pattern of 1,3,5-trisubstituted 4,5-dihydropyrazoles as potent cannabinoid CB(1) receptor antagonists.

Lange JH, van der Neut MA, den Hartog AP, Wals HC, Hoogendoorn J, van Stuivenberg HH, van Vliet BJ, Kruse CG.

Bioorg Med Chem Lett. 2010 Mar 1;20(5):1752-7. doi: 10.1016/j.bmcl.2010.01.049. Epub 2010 Jan 20.

PMID:
20137935
42.

SLV330, a cannabinoid CB1 receptor antagonist, ameliorates deficits in the T-maze, object recognition and Social Recognition Tasks in rodents.

de Bruin NM, Prickaerts J, Lange JH, Akkerman S, Andriambeloson E, de Haan M, Wijnen J, van Drimmelen M, Hissink E, Heijink L, Kruse CG.

Neurobiol Learn Mem. 2010 May;93(4):522-31. doi: 10.1016/j.nlm.2010.01.010. Epub 2010 Feb 2.

PMID:
20132903
43.

Design, synthesis, biological properties, and molecular modeling investigations of novel tacrine derivatives with a combination of acetylcholinesterase inhibition and cannabinoid CB1 receptor antagonism.

Lange JH, Coolen HK, van der Neut MA, Borst AJ, Stork B, Verveer PC, Kruse CG.

J Med Chem. 2010 Feb 11;53(3):1338-46. doi: 10.1021/jm901614b.

PMID:
20047331
44.

Synthesis and SAR of novel imidazoles as potent and selective cannabinoid CB2 receptor antagonists with high binding efficiencies.

Lange JH, van der Neut MA, Wals HC, Kuil GD, Borst AJ, Mulder A, den Hartog AP, Zilaout H, Goutier W, van Stuivenberg HH, van Vliet BJ.

Bioorg Med Chem Lett. 2010 Feb 1;20(3):1084-9. doi: 10.1016/j.bmcl.2009.12.032. Epub 2009 Dec 11.

PMID:
20031412
45.

Influenza: spread by rapid travel.

Lange JH, Cegolon L, Mastrangelo G.

Singapore Med J. 2009 Oct;50(10):1032. No abstract available.

46.

Synthesis and SAR of 1,4,5,6-tetrahydropyridazines as potent cannabinoid CB1 receptor antagonists.

Lange JH, den Hartog AP, van der Neut MA, van Vliet BJ, Kruse CG.

Bioorg Med Chem Lett. 2009 Oct 1;19(19):5675-8. doi: 10.1016/j.bmcl.2009.08.007. Epub 2009 Aug 7.

PMID:
19699640
47.

Asbestos exposure and benign asbestos diseases in 772 formerly exposed workers: dose-response relationships.

Mastrangelo G, Ballarin MN, Bellini E, Bicciato F, Zannol F, Gioffrè F, Zedde A, Tessadri G, Fedeli U, Valentini F, Scoizzato L, Marangi G, Lange JH.

Am J Ind Med. 2009 Aug;52(8):596-602. doi: 10.1002/ajim.20713.

PMID:
19533676
48.

Charles Robert Darwin: 200 years old.

Lange JH.

Singapore Med J. 2009 Feb;50(2):227-8. No abstract available.

49.

Exposure to hydrogen peroxide and eye and nose symptoms among workers in a beverage processing plant.

Mastrangelo G, Zanibellato R, Fadda E, Lange JH, Scoizzato L, Rylander R.

Ann Occup Hyg. 2009 Mar;53(2):161-5. doi: 10.1093/annhyg/men077. Epub 2008 Dec 24.

PMID:
19109442
50.

Cannabinoid CB1 receptor antagonists in therapeutic and structural perspectives.

Lange JH, Kruse CG.

Chem Rec. 2008;8(3):156-68. doi: 10.1002/tcr.20147.

PMID:
18563799

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