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Items: 1 to 50 of 135

1.

High affinity binding of H3K14ac through collaboration of bromodomains 2, 4 and 5 is critical for the molecular and tumor suppressor functions of PBRM1.

Liao L, Alicea-Velázquez NL, Langbein L, Niu X, Cai W, Cho EA, Zhang M, Greer CB, Yan Q, Cosgrove MS, Yang H.

Mol Oncol. 2018 Dec 26. doi: 10.1002/1878-0261.12434. [Epub ahead of print]

2.

Differential Evolution of the Epidermal Keratin Cytoskeleton in Terrestrial and Aquatic Mammals.

Ehrlich F, Fischer H, Langbein L, Praetzel-Wunder S, Ebner B, Figlak K, Weissenbacher A, Sipos W, Tschachler E, Eckhart L.

Mol Biol Evol. 2019 Feb 1;36(2):328-340. doi: 10.1093/molbev/msy214.

PMID:
30517738
3.

Multiple tumor suppressors regulate a HIF-dependent negative feedback loop via ISGF3 in human clear cell renal cancer.

Liao L, Liu ZZ, Langbein L, Cai W, Cho EA, Na J, Niu X, Jiang W, Zhong Z, Cai WL, Jagannathan G, Dulaimi E, Testa JR, Uzzo RG, Wang Y, Stark GR, Sun J, Peiper S, Xu Y, Yan Q, Yang H.

Elife. 2018 Oct 25;7. pii: e37925. doi: 10.7554/eLife.37925.

4.

Kinetochore Components Required for Centromeric Chromatin Assembly Are Impacted by Msc1 in Schizosaccharomyces pombe.

Gao C, Langbein L, Kamal F, George AA, Walworth NC.

Genetics. 2017 Oct;207(2):559-569. doi: 10.1534/genetics.117.300183. Epub 2017 Aug 21.

5.

Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis.

Fleger-Weckmann A, Üstün Y, Kloepper J, Paus R, Bloch W, Chen ZL, Wegner J, Sorokin L, Langbein L, Eckes B, Zigrino P, Krieg T, Nischt R.

Matrix Biol. 2016 Dec;56:42-56. doi: 10.1016/j.matbio.2016.05.002. Epub 2016 May 25.

PMID:
27234308
6.

Acquired Localized (Monodactylous) Longitudinal Pachyonychia and Onychocytic Carcinoma In Situ (2 Cases): Part II.

Perrin C, Cannata GE, Ambrosetti D, Patouraux S, Langbein L, Schweizer J.

Am J Dermatopathol. 2017 Jan;39(1):40-44. doi: 10.1097/DAD.0000000000000579.

PMID:
27219353
7.

Acquired Localized Longitudinal Pachyonychia and Onychomatrical Tumors: A Comparative Study to Onychomatricomas (5 Cases) and Onychocytic Matricomas (4 Cases).

Perrin C, Cannata GE, Langbein L, Ambrosetti D, Coutts M, Balaguer T, Garzon JM, Michiels JF.

Am J Dermatopathol. 2016 Sep;38(9):664-71. doi: 10.1097/DAD.0000000000000511.

PMID:
26978004
8.

Mitotic Diversity in Homeostatic Human Interfollicular Epidermis.

Nöske K, Stark HJ, Nevaril L, Berning M, Langbein L, Goyal A, Diederichs S, Boukamp P.

Int J Mol Sci. 2016 Jan 28;17(2). pii: E167. doi: 10.3390/ijms17020167.

9.

Keratins K2 and K10 are essential for the epidermal integrity of plantar skin.

Fischer H, Langbein L, Reichelt J, Buchberger M, Tschachler E, Eckhart L.

J Dermatol Sci. 2016 Jan;81(1):10-6. doi: 10.1016/j.jdermsci.2015.10.008. Epub 2015 Oct 22.

PMID:
26603179
10.

Localisation of keratin K78 in the basal layer and first suprabasal layers of stratified epithelia completes expression catalogue of type II keratins and provides new insights into sequential keratin expression.

Langbein L, Eckhart L, Fischer H, Rogers MA, Praetzel-Wunder S, Parry DA, Kittstein W, Schweizer J.

Cell Tissue Res. 2016 Mar;363(3):735-50. doi: 10.1007/s00441-015-2278-5. Epub 2015 Sep 4.

PMID:
26340985
11.

Loss of keratin K2 expression causes aberrant aggregation of K10, hyperkeratosis, and inflammation.

Fischer H, Langbein L, Reichelt J, Praetzel-Wunder S, Buchberger M, Ghannadan M, Tschachler E, Eckhart L.

J Invest Dermatol. 2014 Oct;134(10):2579-2588. doi: 10.1038/jid.2014.197. Epub 2014 Apr 21.

12.

Skin tumors with matrical differentiation: lessons from hair keratins, beta-catenin and PHLDA-1 expression.

Battistella M, Carlson JA, Osio A, Langbein L, Cribier B.

J Cutan Pathol. 2014 May;41(5):427-36. doi: 10.1111/cup.12313. Epub 2014 Mar 6.

PMID:
24673383
13.

Activation of Nrf2 in keratinocytes causes chloracne (MADISH)-like skin disease in mice.

Schäfer M, Willrodt AH, Kurinna S, Link AS, Farwanah H, Geusau A, Gruber F, Sorg O, Huebner AJ, Roop DR, Sandhoff K, Saurat JH, Tschachler E, Schneider MR, Langbein L, Bloch W, Beer HD, Werner S.

EMBO Mol Med. 2014 Apr;6(4):442-57. doi: 10.1002/emmm.201303281. Epub 2014 Feb 6.

14.

New facets of keratin K77: interspecies variations of expression and different intracellular location in embryonic and adult skin of humans and mice.

Langbein L, Reichelt J, Eckhart L, Praetzel-Wunder S, Kittstein W, Gassler N, Schweizer J.

Cell Tissue Res. 2013 Dec;354(3):793-812. doi: 10.1007/s00441-013-1716-5. Epub 2013 Sep 22.

PMID:
24057875
15.

Differentiation of epidermal keratinocytes is dependent on glucosylceramide:ceramide processing.

Amen N, Mathow D, Rabionet M, Sandhoff R, Langbein L, Gretz N, Jäckel C, Gröne HJ, Jennemann R.

Hum Mol Genet. 2013 Oct 15;22(20):4164-79. doi: 10.1093/hmg/ddt264. Epub 2013 Jun 6.

PMID:
23748427
16.

Onychocytic carcinoma: a new entity.

Perrin C, Langbein L, Ambrossetti D, Erfan N, Schweizer J, Michiels JF.

Am J Dermatopathol. 2013 Aug;35(6):679-84. doi: 10.1097/DAD.0b013e3182827fec.

PMID:
23518638
17.

Keratins of the human occipital hair medulla: androgenic regulation of in vitro hair keratin K37 expression.

Yoshida H, Taguchi H, Kitahara T, Takema Y, Visscher MO, Schweizer J, Langbein L.

Br J Dermatol. 2013 Jul;169(1):218-21. doi: 10.1111/bjd.12278. No abstract available.

PMID:
23413938
18.

Is thyrotropin-releasing hormone a novel neuroendocrine modulator of keratin expression in human skin?

Ramot Y, Zhang G, Bíró T, Langbein L, Paus R.

Br J Dermatol. 2013 Jul;169(1):146-51. doi: 10.1111/bjd.12264.

PMID:
23373458
19.

Nonsense mutations in AAGAB cause punctate palmoplantar keratoderma type Buschke-Fischer-Brauer.

Giehl KA, Eckstein GN, Pasternack SM, Praetzel-Wunder S, Ruzicka T, Lichtner P, Seidl K, Rogers M, Graf E, Langbein L, Braun-Falco M, Betz RC, Strom TM.

Am J Hum Genet. 2012 Oct 5;91(4):754-9. doi: 10.1016/j.ajhg.2012.08.024. Epub 2012 Sep 20.

20.

Synthesis of porcine pCLCA2 protein during late differentiation of keratinocytes of epidermis and hair follicle inner root sheath.

Plog S, Mundhenk L, Langbein L, Gruber AD.

Cell Tissue Res. 2012 Dec;350(3):445-53. doi: 10.1007/s00441-012-1482-9. Epub 2012 Sep 12.

PMID:
22968961
21.

TSH is a novel neuroendocrine regulator of selected keratins in the human hair follicle.

Ramot Y, Zhang G, Bíró T, Lisztes E, Funk W, Ingber A, Langbein L, Paus R.

J Dermatol Sci. 2011 Oct;64(1):67-70. doi: 10.1016/j.jdermsci.2011.06.005. Epub 2011 Jun 23. No abstract available.

PMID:
21763112
22.

Onychomatricoma in the light of the microanatomy of the normal nail unit.

Perrin C, Langbein L, Schweizer J, Cannata GE, Balaguer T, Chignon-Sicart B, Garzon JM, Benchetrit M, Michiels JF.

Am J Dermatopathol. 2011 Apr;33(2):131-9. doi: 10.1097/DAD.0b013e3181f8c39a.

PMID:
21358379
23.

A decisive function of transforming growth factor-β/Smad signaling in tissue morphogenesis and differentiation of human HaCaT keratinocytes.

Buschke S, Stark HJ, Cerezo A, Prätzel-Wunder S, Boehnke K, Kollar J, Langbein L, Heldin CH, Boukamp P.

Mol Biol Cell. 2011 Mar 15;22(6):782-94. doi: 10.1091/mbc.E10-11-0879. Epub 2011 Feb 2.

24.

Against the rules: human keratin K80: two functional alternative splice variants, K80 and K80.1, with special cellular localization in a wide range of epithelia.

Langbein L, Eckhart L, Rogers MA, Praetzel-Wunder S, Schweizer J.

J Biol Chem. 2010 Nov 19;285(47):36909-21. doi: 10.1074/jbc.M110.161745. Epub 2010 Sep 15.

25.

From hidroacanthoma simplex to poroid hidradenoma: clinicopathologic and immunohistochemic study of poroid neoplasms and reappraisal of their histogenesis.

Battistella M, Langbein L, Peltre B, Cribier B.

Am J Dermatopathol. 2010 Jul;32(5):459-68. doi: 10.1097/DAD.0b013e3181bc91ff.

PMID:
20571345
26.

Alternative splicing of human papillomavirus type-16 E6/E6* early mRNA is coupled to EGF signaling via Erk1/2 activation.

Rosenberger S, De-Castro Arce J, Langbein L, Steenbergen RD, Rösl F.

Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):7006-11. doi: 10.1073/pnas.1002620107. Epub 2010 Mar 29.

27.

Expression of the orphan protein Plet-1 during trichilemmal differentiation of anagen hair follicles.

Raymond K, Richter A, Kreft M, Frijns E, Janssen H, Slijper M, Praetzel-Wunder S, Langbein L, Sonnenberg A.

J Invest Dermatol. 2010 Jun;130(6):1500-13. doi: 10.1038/jid.2010.4. Epub 2010 Feb 4.

28.

Prolactin--a novel neuroendocrine regulator of human keratin expression in situ.

Ramot Y, Bíró T, Tiede S, Tóth BI, Langan EA, Sugawara K, Foitzik K, Ingber A, Goffin V, Langbein L, Paus R.

FASEB J. 2010 Jun;24(6):1768-79. doi: 10.1096/fj.09-146415. Epub 2010 Jan 26.

PMID:
20103718
29.

N-WASP is a novel regulator of hair-follicle cycling that controls antiproliferative TGF{beta} pathways.

Lefever T, Pedersen E, Basse A, Paus R, Quondamatteo F, Stanley AC, Langbein L, Wu X, Wehland J, Lommel S, Brakebusch C.

J Cell Sci. 2010 Jan 1;123(Pt 1):128-40. doi: 10.1242/jcs.053835.

30.

BPAG1 isoform-b: complex distribution pattern in striated and heart muscle and association with plectin and alpha-actinin.

Steiner-Champliaud MF, Schneider Y, Favre B, Paulhe F, Praetzel-Wunder S, Faulkner G, Konieczny P, Raith M, Wiche G, Adebola A, Liem RK, Langbein L, Sonnenberg A, Fontao L, Borradori L.

Exp Cell Res. 2010 Feb 1;316(3):297-313. doi: 10.1016/j.yexcr.2009.11.010. Epub 2009 Nov 28.

PMID:
19932097
31.

Identification of a novel family of laminin N-terminal alternate splice isoforms: structural and functional characterization.

Hamill KJ, Langbein L, Jones JC, McLean WH.

J Biol Chem. 2009 Dec 18;284(51):35588-96. doi: 10.1074/jbc.M109.052811.

32.

The keratins of the human beard hair medulla: the riddle in the middle.

Langbein L, Yoshida H, Praetzel-Wunder S, Parry DA, Schweizer J.

J Invest Dermatol. 2010 Jan;130(1):55-73. doi: 10.1038/jid.2009.192. Erratum in: J Invest Dermatol. 2010 Jun;130(6):1750.

33.

The 'melanocyte-keratin' mystery revisited: neither normal human epidermal nor hair follicle melanocytes express keratin 16 or keratin 6 in situ.

Ramot Y, Gáspár E, Dendorfer A, Langbein L, Paus R.

Br J Dermatol. 2009 Oct;161(4):933-8. doi: 10.1111/j.1365-2133.2009.09294.x. Epub 2009 Jun 9.

PMID:
19519832
34.

Claudin-7 regulates EpCAM-mediated functions in tumor progression.

Nübel T, Preobraschenski J, Tuncay H, Weiss T, Kuhn S, Ladwein M, Langbein L, Zöller M.

Mol Cancer Res. 2009 Mar;7(3):285-99. doi: 10.1158/1541-7786.MCR-08-0200. Epub 2009 Mar 10.

35.

E7 oncoprotein of novel human papillomavirus type 108 lacking the E6 gene induces dysplasia in organotypic keratinocyte cultures.

Nobre RJ, Herráez-Hernández E, Fei JW, Langbein L, Kaden S, Gröne HJ, de Villiers EM.

J Virol. 2009 Apr;83(7):2907-16. doi: 10.1128/JVI.02490-08. Epub 2009 Jan 19.

36.

Human female hair follicles are a direct, nonclassical target for thyroid-stimulating hormone.

Bodó E, Kromminga A, Bíró T, Borbíró I, Gáspár E, Zmijewski MA, van Beek N, Langbein L, Slominski AT, Paus R.

J Invest Dermatol. 2009 May;129(5):1126-39. doi: 10.1038/jid.2008.361. Epub 2008 Dec 4.

37.

Characterization and expression analysis of the hair keratin associated protein KAP26.1.

Rogers MA, Langbein L, Praetzel-Wunder S, Giehl K.

Br J Dermatol. 2008 Sep;159(3):725-9. doi: 10.1111/j.1365-2133.2008.08743.x. Epub 2008 Jul 19.

PMID:
18647308
38.

New concepts on the histogenesis of eccrine neoplasia from keratin expression in the normal eccrine gland, syringoma and poroma.

Langbein L, Cribier B, Schirmacher P, Praetzel-Wunder S, Peltre B, Schweizer J.

Br J Dermatol. 2008 Sep;159(3):633-45. doi: 10.1111/j.1365-2133.2008.08746.x. Epub 2008 Jul 19.

PMID:
18647305
39.

The human keratins: biology and pathology.

Moll R, Divo M, Langbein L.

Histochem Cell Biol. 2008 Jun;129(6):705-33. doi: 10.1007/s00418-008-0435-6. Epub 2008 May 7. Review.

40.

The Ki67+ proliferation index correlates with increased cellular retinol-binding protein-1 and the coordinated loss of plakophilin-1 and desmoplakin during progression of cervical squamous lesions.

Schmitt-Graeff A, Koeninger A, Olschewski M, Haxelmans S, Nitschke R, Bochaton-Piallat ML, Lifschitz-Mercer B, Gabbiani G, Langbein L, Czernobilsky B.

Histopathology. 2007 Jul;51(1):87-97.

PMID:
17593084
41.

A complex of EpCAM, claudin-7, CD44 variant isoforms, and tetraspanins promotes colorectal cancer progression.

Kuhn S, Koch M, Nübel T, Ladwein M, Antolovic D, Klingbeil P, Hildebrand D, Moldenhauer G, Langbein L, Franke WW, Weitz J, Zöller M.

Mol Cancer Res. 2007 Jun;5(6):553-67.

42.

Integrin-linked kinase is required for epidermal and hair follicle morphogenesis.

Lorenz K, Grashoff C, Torka R, Sakai T, Langbein L, Bloch W, Aumailley M, Fässler R.

J Cell Biol. 2007 May 7;177(3):501-13.

43.

Hair follicle-specific keratins and their diseases.

Schweizer J, Langbein L, Rogers MA, Winter H.

Exp Cell Res. 2007 Jun 10;313(10):2010-20. Epub 2007 Mar 14. Review.

PMID:
17428470
44.

Novel type I hair keratins K39 and K40 are the last to be expressed in differentiation of the hair: completion of the human hair keratin catalog.

Langbein L, Rogers MA, Praetzel-Wunder S, Böckler D, Schirmacher P, Schweizer J.

J Invest Dermatol. 2007 Jun;127(6):1532-5. Epub 2007 Feb 15. No abstract available.

45.

Characterization of human KAP24.1, a cuticular hair keratin-associated protein with unusual amino-acid composition and repeat structure.

Rogers MA, Winter H, Langbein L, Wollschläger A, Praetzel-Wunder S, Jave-Suarez LF, Schweizer J.

J Invest Dermatol. 2007 May;127(5):1197-204. Epub 2007 Jan 18.

46.

Integrity and barrier function of the epidermis critically depend on glucosylceramide synthesis.

Jennemann R, Sandhoff R, Langbein L, Kaden S, Rothermel U, Gallala H, Sandhoff K, Wiegandt H, Gröne HJ.

J Biol Chem. 2007 Feb 2;282(5):3083-94. Epub 2006 Dec 4.

47.

Rac1 is crucial for hair follicle integrity but is not essential for maintenance of the epidermis.

Chrostek A, Wu X, Quondamatteo F, Hu R, Sanecka A, Niemann C, Langbein L, Haase I, Brakebusch C.

Mol Cell Biol. 2006 Sep;26(18):6957-70.

48.

Human hair keratin-associated proteins (KAPs).

Rogers MA, Langbein L, Praetzel-Wunder S, Winter H, Schweizer J.

Int Rev Cytol. 2006;251:209-63. Review.

PMID:
16939781
49.

K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), and K28 (K25irs4) represent the type I inner root sheath keratins of the human hair follicle.

Langbein L, Rogers MA, Praetzel-Wunder S, Helmke B, Schirmacher P, Schweizer J.

J Invest Dermatol. 2006 Nov;126(11):2377-86. Epub 2006 Jul 27.

50.

New consensus nomenclature for mammalian keratins.

Schweizer J, Bowden PE, Coulombe PA, Langbein L, Lane EB, Magin TM, Maltais L, Omary MB, Parry DA, Rogers MA, Wright MW.

J Cell Biol. 2006 Jul 17;174(2):169-74. Epub 2006 Jul 10.

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