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Items: 1 to 50 of 200

1.

Circadian Regulator CLOCK Recruits Immune-Suppressive Microglia into the GBM Tumor Microenvironment.

Chen P, Hsu WH, Chang A, Tan Z, Lan Z, Zhou A, Spring DJ, Lang FF, Wang YA, DePinho RA.

Cancer Discov. 2020 Mar;10(3):371-381. doi: 10.1158/2159-8290.CD-19-0400. Epub 2020 Jan 9.

PMID:
31919052
2.

Window-of-opportunity clinical trial of pembrolizumab in patients with recurrent glioblastoma reveals predominance of immune-suppressive macrophages.

de Groot J, Penas-Prado M, Alfaro-Munoz KD, Hunter K, Pei B, O'brien B, Weathers SP, Loghin M, Kamiya Matsouka C, Yung WKA, Mandel J, Wu J, Yuan Y, Zhou S, Fuller GN, Huse J, Rao G, Weinberg JS, Prabhu SS, McCutcheon IE, Lang FF, Ferguson SD, Sawaya R, Colen R, Yadav SS, Blando J, Vence L, Allison J, Sharma P, Heimberger AB.

Neuro Oncol. 2019 Nov 22. pii: noz185. doi: 10.1093/neuonc/noz185. [Epub ahead of print]

PMID:
31755915
3.

Advances in endovascular neuro-oncology: endovascular selective intra-arterial (ESIA) infusion of targeted biologic therapy for brain tumors.

Srinivasan VM, Lang FF, Chen SR, Chen MM, Gumin J, Johnson J, Burkhardt JK, Kan P.

J Neurointerv Surg. 2020 Feb;12(2):197-203. doi: 10.1136/neurintsurg-2019-015137. Epub 2019 Nov 1. Review.

PMID:
31676690
4.

GITRL-armed Delta-24-RGD oncolytic adenovirus prolongs survival and induces anti-glioma immune memory.

Rivera-Molina Y, Jiang H, Fueyo J, Nguyen T, Shin DH, Youssef G, Fan X, Gumin J, Alonso MM, Phadnis S, Lang FF, Gomez-Manzano C.

Neurooncol Adv. 2019 May-Dec;1(1):vdz009. doi: 10.1093/noajnl/vdz009. Epub 2019 Jun 5.

5.

Microcatheter delivery of neurotherapeutics: compatibility with mesenchymal stem cells.

Srinivasan VM, Gumin J, Camstra KM, Chen SR, Johnson JN, Shimizu Y, Parker Kerrigan BC, Shpall EJ, Lang FF, Kan P.

J Neurosurg. 2019 Sep 6:1-9. doi: 10.3171/2019.6.JNS19327. [Epub ahead of print]

PMID:
31491769
6.

Localized Treatment with Oncolytic Adenovirus Delta-24-RGDOX Induces Systemic Immunity against Disseminated Subcutaneous and Intracranial Melanomas.

Jiang H, Shin DH, Nguyen TT, Fueyo J, Fan X, Henry V, Carrillo CC, Yi Y, Alonso MM, Collier TL, Yuan Y, Lang FF, Gomez-Manzano C.

Clin Cancer Res. 2019 Nov 15;25(22):6801-6814. doi: 10.1158/1078-0432.CCR-19-0405. Epub 2019 Aug 27.

PMID:
31455679
7.

Biological subtypes and survival outcomes in breast cancer patients with brain metastases in the targeted therapy era.

Bastos DCA, Maldaun MVC, Sawaya R, Suki D, Lang FF, Brown PD, Rao G, Weinberg JS, Prabhu SS.

Neurooncol Pract. 2018 Aug;5(3):161-169. doi: 10.1093/nop/npx033. Epub 2017 Dec 23.

8.

Suppressed immune microenvironment and repertoire in brain metastases from patients with resected non-small-cell lung cancer.

Kudo Y, Haymaker C, Zhang J, Reuben A, Duose DY, Fujimoto J, Roy-Chowdhuri S, Solis Soto LM, Dejima H, Parra ER, Mino B, Abraham R, Ikeda N, Vaporcyan A, Gibbons D, Zhang J, Lang FF, Luthra R, Lee JJ, Moran C, Huse JT, Kadara H, Wistuba II.

Ann Oncol. 2019 Sep 1;30(9):1521-1530. doi: 10.1093/annonc/mdz207.

PMID:
31282941
9.

REST-DRD2 mechanism impacts glioblastoma stem cell-mediated tumorigenesis.

Marisetty AL, Lu L, Veo BL, Liu B, Coarfa C, Kamal MM, Kassem DH, Irshad K, Lu Y, Gumin J, Henry V, Paulucci-Holthauzen A, Rao G, Baladandayuthapani V, Lang FF, Fuller GN, Majumder S.

Neuro Oncol. 2019 Jun 10;21(6):775-785. doi: 10.1093/neuonc/noz030.

PMID:
30953587
10.

Perilesional Resection of Glioblastoma Is Independently Associated With Improved Outcomes.

Al-Holou WN, Hodges TR, Everson RG, Freeman J, Zhou S, Suki D, Rao G, Ferguson SD, Heimberger AB, McCutcheon IE, Prabhu SS, Lang FF, Weinberg JS, Wildrick DM, Sawaya R.

Neurosurgery. 2020 Jan 1;86(1):112-121. doi: 10.1093/neuros/nyz008.

PMID:
30799490
11.

Distinct mechanisms enable inward or outward budding from late endosomes/multivesicular bodies.

Gireud-Goss M, Reyes S, Wilson M, Farley M, Memarzadeh K, Srinivasan S, Sirisaengtaksin N, Yamashita S, Tsunoda S, Lang FF, Waxham MN, Bean AJ.

Exp Cell Res. 2018 Nov 1;372(1):1-15. doi: 10.1016/j.yexcr.2018.08.027. Epub 2018 Aug 23.

PMID:
30144444
12.

A Coclinical Radiogenomic Validation Study: Conserved Magnetic Resonance Radiomic Appearance of Periostin-Expressing Glioblastoma in Patients and Xenograft Models.

Zinn PO, Singh SK, Kotrotsou A, Hassan I, Thomas G, Luedi MM, Elakkad A, Elshafeey N, Idris T, Mosley J, Gumin J, Fuller GN, de Groot JF, Baladandayuthapani V, Sulman EP, Kumar AJ, Sawaya R, Lang FF, Piwnica-Worms D, Colen RR.

Clin Cancer Res. 2018 Dec 15;24(24):6288-6299. doi: 10.1158/1078-0432.CCR-17-3420. Epub 2018 Jul 27.

13.

Stem Cell Therapy of Gliomas.

Parker Kerrigan BC, Hossain A, Yamashita S, Lang FF.

Prog Neurol Surg. 2018;32:124-151. doi: 10.1159/000469686. Epub 2018 Jul 10. Review.

PMID:
29990980
14.

Metastatic Brain Tumors Disrupt the Blood-Brain Barrier and Alter Lipid Metabolism by Inhibiting Expression of the Endothelial Cell Fatty Acid Transporter Mfsd2a.

Tiwary S, Morales JE, Kwiatkowski SC, Lang FF, Rao G, McCarty JH.

Sci Rep. 2018 May 29;8(1):8267. doi: 10.1038/s41598-018-26636-6.

15.

MRI venous architecture of insula.

Gogia B, Chavali LS, Lang FF, Hayman LA, Rai P, Prabhu SS, Schomer DF, Kumar VA.

J Neurol Sci. 2018 Jul 15;390:156-161. doi: 10.1016/j.jns.2018.04.032. Epub 2018 Apr 22.

PMID:
29801878
16.

A gene expression signature predicts recurrence-free survival in meningioma.

Olar A, Goodman LD, Wani KM, Boehling NS, Sharma DS, Mody RR, Gumin J, Claus EB, Lang FF, Cloughesy TF, Lai A, Aldape KD, DeMonte F, Sulman EP.

Oncotarget. 2018 Feb 15;9(22):16087-16098. doi: 10.18632/oncotarget.24498. eCollection 2018 Mar 23.

17.

Magnetic resonance and photoacoustic imaging of brain tumor mediated by mesenchymal stem cell labeled with multifunctional nanoparticle introduced via carotid artery injection.

Qiao Y, Gumin J, MacLellan CJ, Gao F, Bouchard R, Lang FF, Stafford RJ, Melancon MP.

Nanotechnology. 2018 Apr 20;29(16):165101. doi: 10.1088/1361-6528/aaaf16.

18.

Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma.

Lang FF, Conrad C, Gomez-Manzano C, Yung WKA, Sawaya R, Weinberg JS, Prabhu SS, Rao G, Fuller GN, Aldape KD, Gumin J, Vence LM, Wistuba I, Rodriguez-Canales J, Villalobos PA, Dirven CMF, Tejada S, Valle RD, Alonso MM, Ewald B, Peterkin JJ, Tufaro F, Fueyo J.

J Clin Oncol. 2018 May 10;36(14):1419-1427. doi: 10.1200/JCO.2017.75.8219. Epub 2018 Feb 12.

19.

Dexamethasone-mediated oncogenicity in vitro and in an animal model of glioblastoma.

Luedi MM, Singh SK, Mosley JC, Hassan ISA, Hatami M, Gumin J, Andereggen L, Sulman EP, Lang FF, Stueber F, Fuller GN, Colen RR, Zinn PO.

J Neurosurg. 2018 Dec 1;129(6):1446-1455. doi: 10.3171/2017.7.JNS17668.

PMID:
29328002
20.

Large Scale Identification of Variant Proteins in Glioma Stem Cells.

Mostovenko E, Végvári Á, Rezeli M, Lichti CF, Fenyö D, Wang Q, Lang FF, Sulman EP, Sahlin KB, Marko-Varga G, Nilsson CL.

ACS Chem Neurosci. 2018 Jan 17;9(1):73-79. doi: 10.1021/acschemneuro.7b00362. Epub 2017 Dec 21.

21.

Mesenchymal stem cells as natural biofactories for exosomes carrying miR-124a in the treatment of gliomas.

Lang FM, Hossain A, Gumin J, Momin EN, Shimizu Y, Ledbetter D, Shahar T, Yamashita S, Parker Kerrigan B, Fueyo J, Sawaya R, Lang FF.

Neuro Oncol. 2018 Feb 19;20(3):380-390. doi: 10.1093/neuonc/nox152.

22.

A Cationic Coordination Polymer and Its Orange II Anion-Exchanged Products: Isolation, Structural Characterization, Photocurrent Responses, and Dielectric Properties.

Liu D, Lang FF, Zhou X, Ren ZG, Young DJ, Lang JP.

Inorg Chem. 2017 Oct 16;56(20):12542-12550. doi: 10.1021/acs.inorgchem.7b02034. Epub 2017 Oct 2.

PMID:
28967747
23.

Exosomes from Glioma-Associated Mesenchymal Stem Cells Increase the Tumorigenicity of Glioma Stem-like Cells via Transfer of miR-1587.

Figueroa J, Phillips LM, Shahar T, Hossain A, Gumin J, Kim H, Bean AJ, Calin GA, Fueyo J, Walters ET, Kalluri R, Verhaak RG, Lang FF.

Cancer Res. 2017 Nov 1;77(21):5808-5819. doi: 10.1158/0008-5472.CAN-16-2524. Epub 2017 Aug 30.

24.

Glioblastoma stem cells exploit the αvβ8 integrin-TGFβ1 signaling axis to drive tumor initiation and progression.

Guerrero PA, Tchaicha JH, Chen Z, Morales JE, McCarty N, Wang Q, Sulman EP, Fuller G, Lang FF, Rao G, McCarty JH.

Oncogene. 2017 Nov 23;36(47):6568-6580. doi: 10.1038/onc.2017.248. Epub 2017 Aug 7.

25.

TIE2 Associates with Caveolae and Regulates Caveolin-1 To Promote Their Nuclear Translocation.

Hossain MB, Shifat R, Li J, Luo X, Hess KR, Rivera-Molina Y, Puerta Martinez F, Jiang H, Lang FF, Hung MC, Fueyo J, Gomez-Manzano C.

Mol Cell Biol. 2017 Oct 13;37(21). pii: e00142-17. doi: 10.1128/MCB.00142-17. Print 2017 Nov 1.

26.

Post-operative stereotactic radiosurgery versus observation for completely resected brain metastases: a single-centre, randomised, controlled, phase 3 trial.

Mahajan A, Ahmed S, McAleer MF, Weinberg JS, Li J, Brown P, Settle S, Prabhu SS, Lang FF, Levine N, McGovern S, Sulman E, McCutcheon IE, Azeem S, Cahill D, Tatsui C, Heimberger AB, Ferguson S, Ghia A, Demonte F, Raza S, Guha-Thakurta N, Yang J, Sawaya R, Hess KR, Rao G.

Lancet Oncol. 2017 Aug;18(8):1040-1048. doi: 10.1016/S1470-2045(17)30414-X. Epub 2017 Jul 4. Erratum in: Lancet Oncol. 2017 Aug;18(8):e433. Lancet Oncol. 2017 Sep;18(9):e510.

27.

Efficacy of Onalespib, a Long-Acting Second-Generation HSP90 Inhibitor, as a Single Agent and in Combination with Temozolomide against Malignant Gliomas.

Canella A, Welker AM, Yoo JY, Xu J, Abas FS, Kesanakurti D, Nagarajan P, Beattie CE, Sulman EP, Liu J, Gumin J, Lang FF, Gurcan MN, Kaur B, Sampath D, Puduvalli VK.

Clin Cancer Res. 2017 Oct 15;23(20):6215-6226. doi: 10.1158/1078-0432.CCR-16-3151. Epub 2017 Jul 5.

28.

Oncolytic Adenovirus and Tumor-Targeting Immune Modulatory Therapy Improve Autologous Cancer Vaccination.

Jiang H, Rivera-Molina Y, Gomez-Manzano C, Clise-Dwyer K, Bover L, Vence LM, Yuan Y, Lang FF, Toniatti C, Hossain MB, Fueyo J.

Cancer Res. 2017 Jul 15;77(14):3894-3907. doi: 10.1158/0008-5472.CAN-17-0468. Epub 2017 May 31.

29.

Detection of wild-type EGFR amplification and EGFRvIII mutation in CSF-derived extracellular vesicles of glioblastoma patients.

Figueroa JM, Skog J, Akers J, Li H, Komotar R, Jensen R, Ringel F, Yang I, Kalkanis S, Thompson R, LoGuidice L, Berghoff E, Parsa A, Liau L, Curry W, Cahill D, Bettegowda C, Lang FF, Chiocca EA, Henson J, Kim R, Breakefield X, Chen C, Messer K, Hochberg F, Carter BS.

Neuro Oncol. 2017 Oct 19;19(11):1494-1502. doi: 10.1093/neuonc/nox085.

30.

Percentage of mesenchymal stem cells in high-grade glioma tumor samples correlates with patient survival.

Shahar T, Rozovski U, Hess KR, Hossain A, Gumin J, Gao F, Fuller GN, Goodman L, Sulman EP, Lang FF.

Neuro Oncol. 2017 May 1;19(5):660-668. doi: 10.1093/neuonc/now239.

31.

The surgical treatment of tumors of the fourth ventricle: a single-institution experience.

Ferguson SD, Levine NB, Suki D, Tsung AJ, Lang FF, Sawaya R, Weinberg JS, McCutcheon IE.

J Neurosurg. 2018 Feb;128(2):339-351. doi: 10.3171/2016.11.JNS161167. Epub 2017 Apr 14.

PMID:
28409732
32.

Ionizing radiation augments glioma tropism of mesenchymal stem cells.

Thomas JG, Parker Kerrigan BC, Hossain A, Gumin J, Shinojima N, Nwajei F, Ezhilarasan R, Love P, Sulman EP, Lang FF.

J Neurosurg. 2018 Jan;128(1):287-295. doi: 10.3171/2016.9.JNS16278. Epub 2017 Mar 31.

33.

Mesenchymal stromal cells for the delivery of oncolytic viruses in gliomas.

Parker Kerrigan BC, Shimizu Y, Andreeff M, Lang FF.

Cytotherapy. 2017 Apr;19(4):445-457. doi: 10.1016/j.jcyt.2017.02.002. Epub 2017 Feb 21. Review.

34.

Proceedings of the WFNS Neuro-Oncology Committee Workshop Rome 2015.

Au K, Ram Z, Zadeh G, Aldape K, Balogun J, Barani I, DiMeco F, Goel A, Khu K, Lang FF, Lund-Johansen M, Maldaun M, Tabatabai G, Tonn JC, Westphal M.

Surg Neurol Int. 2016 Dec 12;7(Suppl 40):S963-S975. doi: 10.4103/2152-7806.195563. eCollection 2016. No abstract available.

35.

Preclinical Evaluation of Sequential Combination of Oncolytic Adenovirus Delta-24-RGD and Phosphatidylserine-Targeting Antibody in Pancreatic Ductal Adenocarcinoma.

Dai B, Roife D, Kang Y, Gumin J, Rios Perez MV, Li X, Pratt M, Brekken RA, Fueyo-Margareto J, Lang FF, Fleming JB.

Mol Cancer Ther. 2017 Apr;16(4):662-670. doi: 10.1158/1535-7163.MCT-16-0526. Epub 2017 Jan 30.

36.

Interrogating IDH Mutation in Brain Tumor: Magnetic Resonance and Hyperpolarization.

Hu J, Salzillo TC, Sailasuta N, Lang FF, Bhattacharya P.

Top Magn Reson Imaging. 2017 Feb;26(1):27-32. doi: 10.1097/RMR.0000000000000113. Review.

37.

TMEM43/LUMA is a key signaling component mediating EGFR-induced NF-κB activation and tumor progression.

Jiang C, Zhu Y, Zhou Z, Gumin J, Bengtsson L, Wu W, Songyang Z, Lang FF, Lin X.

Oncogene. 2017 May 18;36(20):2813-2823. doi: 10.1038/onc.2016.430. Epub 2016 Dec 19.

PMID:
27991920
38.

TIE2-mediated tyrosine phosphorylation of H4 regulates DNA damage response by recruiting ABL1.

Hossain MB, Shifat R, Johnson DG, Bedford MT, Gabrusiewicz KR, Cortes-Santiago N, Luo X, Lu Z, Ezhilarasan R, Sulman EP, Jiang H, Li SS, Lang FF, Tyler J, Hung MC, Fueyo J, Gomez-Manzano C.

Sci Adv. 2016 Apr 1;2(4):e1501290. eCollection 2016 Apr.

39.

Interrogating Metabolism in Brain Cancer.

Salzillo TC, Hu J, Nguyen L, Whiting N, Lee J, Weygand J, Dutta P, Pudakalakatti S, Millward NZ, Gammon ST, Lang FF, Heimberger AB, Bhattacharya PK.

Magn Reson Imaging Clin N Am. 2016 Nov;24(4):687-703. doi: 10.1016/j.mric.2016.07.003. Review.

40.

The Cytoskeletal Adapter Protein Spinophilin Regulates Invadopodia Dynamics and Tumor Cell Invasion in Glioblastoma.

Cheerathodi M, Avci NG, Guerrero PA, Tang LK, Popp J, Morales JE, Chen Z, Carnero A, Lang FF, Ballif BA, Rivera GM, McCarty JH.

Mol Cancer Res. 2016 Dec;14(12):1277-1287. Epub 2016 Sep 21.

41.

A Dexamethasone-regulated Gene Signature Is Prognostic for Poor Survival in Glioblastoma Patients.

Luedi MM, Singh SK, Mosley JC, Hatami M, Gumin J, Sulman EP, Lang FF, Stueber F, Zinn PO, Colen RR.

J Neurosurg Anesthesiol. 2017 Jan;29(1):46-58.

42.

Salinomycin induced ROS results in abortive autophagy and leads to regulated necrosis in glioblastoma.

Xipell E, Gonzalez-Huarriz M, Martinez de Irujo JJ, García-Garzón A, Lang FF, Jiang H, Fueyo J, Gomez-Manzano C, Alonso MM.

Oncotarget. 2016 May 24;7(21):30626-41. doi: 10.18632/oncotarget.8905.

43.

Endoplasmic reticulum stress-inducing drugs sensitize glioma cells to temozolomide through downregulation of MGMT, MPG, and Rad51.

Xipell E, Aragón T, Martínez-Velez N, Vera B, Idoate MA, Martínez-Irujo JJ, Garzón AG, Gonzalez-Huarriz M, Acanda AM, Jones C, Lang FF, Fueyo J, Gomez-Manzano C, Alonso MM.

Neuro Oncol. 2016 Aug;18(8):1109-19. doi: 10.1093/neuonc/now022. Epub 2016 Mar 6.

44.

Suppression of RAF/MEK or PI3K synergizes cytotoxicity of receptor tyrosine kinase inhibitors in glioma tumor-initiating cells.

Shingu T, Holmes L, Henry V, Wang Q, Latha K, Gururaj AE, Gibson LA, Doucette T, Lang FF, Rao G, Yuan L, Sulman EP, Farrell NP, Priebe W, Hess KR, Wang YA, Hu J, Bögler O.

J Transl Med. 2016 Feb 9;14:46. doi: 10.1186/s12967-016-0803-2.

45.

Mir-21-Sox2 Axis Delineates Glioblastoma Subtypes with Prognostic Impact.

Sathyan P, Zinn PO, Marisetty AL, Liu B, Kamal MM, Singh SK, Bady P, Lu L, Wani KM, Veo BL, Gumin J, Kassem DH, Robinson F, Weng C, Baladandayuthapani V, Suki D, Colman H, Bhat KP, Sulman EP, Aldape K, Colen RR, Verhaak RG, Lu Z, Fuller GN, Huang S, Lang FF, Sawaya R, Hegi M, Majumder S.

J Neurosci. 2015 Nov 11;35(45):15097-112. doi: 10.1523/JNEUROSCI.1265-15.2015.

46.

Genetic, epigenetic, and molecular landscapes of multifocal and multicentric glioblastoma.

Liu Q, Liu Y, Li W, Wang X, Sawaya R, Lang FF, Yung WK, Chen K, Fuller GN, Zhang W.

Acta Neuropathol. 2015 Oct;130(4):587-97. doi: 10.1007/s00401-015-1470-8. Epub 2015 Sep 1.

47.

Integrated Transcriptomic and Glycomic Profiling of Glioma Stem Cell Xenografts.

Wildburger NC, Zhou S, Zacharias LG, Kroes RA, Moskal JR, Schmidt M, Mirzaei P, Gumin J, Lang FF, Mechref Y, Nilsson CL.

J Proteome Res. 2015 Sep 4;14(9):3932-9. doi: 10.1021/acs.jproteome.5b00549. Epub 2015 Aug 4.

48.

Mesenchymal Stem Cells Isolated From Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL-6/gp130/STAT3 Pathway.

Hossain A, Gumin J, Gao F, Figueroa J, Shinojima N, Takezaki T, Priebe W, Villarreal D, Kang SG, Joyce C, Sulman E, Wang Q, Marini FC, Andreeff M, Colman H, Lang FF.

Stem Cells. 2015 Aug;33(8):2400-15. doi: 10.1002/stem.2053. Epub 2015 May 27.

49.

ESI-MS/MS and MALDI-IMS Localization Reveal Alterations in Phosphatidic Acid, Diacylglycerol, and DHA in Glioma Stem Cell Xenografts.

Wildburger NC, Wood PL, Gumin J, Lichti CF, Emmett MR, Lang FF, Nilsson CL.

J Proteome Res. 2015 Jun 5;14(6):2511-9. doi: 10.1021/acs.jproteome.5b00076. Epub 2015 Apr 29.

50.

Oncolytic adenovirus research evolution: from cell-cycle checkpoints to immune checkpoints.

Jiang H, Gomez-Manzano C, Rivera-Molina Y, Lang FF, Conrad CA, Fueyo J.

Curr Opin Virol. 2015 Aug;13:33-9. doi: 10.1016/j.coviro.2015.03.009. Epub 2015 Apr 13. Review.

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