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Items: 13


Reversal of ApoE4-induced recycling block as a novel prevention approach for Alzheimer's disease.

Xian X, Pohlkamp T, Durakoglugil MS, Wong CH, Beck JK, Lane-Donovan C, Plattner F, Herz J.

Elife. 2018 Oct 30;7. pii: e40048. doi: 10.7554/eLife.40048.


Building a better blood-brain barrier.

Lane-Donovan C, Herz J.

Elife. 2017 Oct 10;6. pii: e31808. doi: 10.7554/eLife.31808.


NGP 555, a γ-Secretase Modulator, Lowers the Amyloid Biomarker, Aβ42, in Cerebrospinal Fluid while Preventing Alzheimer's Disease Cognitive Decline in Rodents.

Kounnas MZ, Lane-Donovan C, Nowakowski DW, Herz J, Comer WT.

Alzheimers Dement (N Y). 2017 Jan;3(1):65-73. doi: 10.1016/j.trci.2016.09.003.


The ApoE receptors Vldlr and Apoer2 in central nervous system function and disease.

Lane-Donovan C, Herz J.

J Lipid Res. 2017 Jun;58(6):1036-1043. doi: 10.1194/jlr.R075507. Epub 2017 Mar 14. Review.


ApoE, ApoE Receptors, and the Synapse in Alzheimer's Disease.

Lane-Donovan C, Herz J.

Trends Endocrinol Metab. 2017 Apr;28(4):273-284. doi: 10.1016/j.tem.2016.12.001. Epub 2017 Jan 2. Review.


Genetic Restoration of Plasma ApoE Improves Cognition and Partially Restores Synaptic Defects in ApoE-Deficient Mice.

Lane-Donovan C, Wong WM, Durakoglugil MS, Wasser CR, Jiang S, Xian X, Herz J.

J Neurosci. 2016 Sep 28;36(39):10141-50. doi: 10.1523/JNEUROSCI.1054-16.2016. Epub 2016 Sep 28.


Physiologic Reelin does not play a strong role in protection against acute stroke.

Lane-Donovan C, Desai C, Pohlkamp T, Plautz EJ, Herz J, Stowe AM.

J Cereb Blood Flow Metab. 2016 Jul;36(7):1295-303. doi: 10.1177/0271678X16646386. Epub 2016 May 4.


High-Fat Diet Changes Hippocampal Apolipoprotein E (ApoE) in a Genotype- and Carbohydrate-Dependent Manner in Mice.

Lane-Donovan C, Herz J.

PLoS One. 2016 Feb 1;11(2):e0148099. doi: 10.1371/journal.pone.0148099. eCollection 2016.


Reelin protects against amyloid β toxicity in vivo.

Lane-Donovan C, Philips GT, Wasser CR, Durakoglugil MS, Masiulis I, Upadhaya A, Pohlkamp T, Coskun C, Kotti T, Steller L, Hammer RE, Frotscher M, Bock HH, Herz J.

Sci Signal. 2015 Jul 7;8(384):ra67. doi: 10.1126/scisignal.aaa6674.


Lrp4 domains differentially regulate limb/brain development and synaptic plasticity.

Pohlkamp T, Durakoglugil M, Lane-Donovan C, Xian X, Johnson EB, Hammer RE, Herz J.

PLoS One. 2015 Feb 17;10(2):e0116701. doi: 10.1371/journal.pone.0116701. eCollection 2015.


Differential splicing and glycosylation of Apoer2 alters synaptic plasticity and fear learning.

Wasser CR, Masiulis I, Durakoglugil MS, Lane-Donovan C, Xian X, Beffert U, Agarwala A, Hammer RE, Herz J.

Sci Signal. 2014 Nov 25;7(353):ra113. doi: 10.1126/scisignal.2005438.


More than cholesterol transporters: lipoprotein receptors in CNS function and neurodegeneration.

Lane-Donovan C, Philips GT, Herz J.

Neuron. 2014 Aug 20;83(4):771-87. doi: 10.1016/j.neuron.2014.08.005. Review.


Is apolipoprotein e required for cognitive function in humans?: implications for Alzheimer drug development.

Lane-Donovan C, Herz J.

JAMA Neurol. 2014 Oct;71(10):1213-5. doi: 10.1001/jamaneurol.2014.2013. No abstract available.

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