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Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

Kim JS, He X, Liu J, Duan Z, Kim T, Gerard J, Kim B, Pillai MM, Lane WS, Noble WS, Budnik B, Waldman T.

J Biol Chem. 2019 May 31;294(22):8760-8772. doi: 10.1074/jbc.RA119.007832. Epub 2019 Apr 22.


Diurnal Rhythms Spatially and Temporally Organize Autophagy.

Ryzhikov M, Ehlers A, Steinberg D, Xie W, Oberlander E, Brown S, Gilmore PE, Townsend RR, Lane WS, Dolinay T, Nakahira K, Choi AMK, Haspel JA.

Cell Rep. 2019 Feb 12;26(7):1880-1892.e6. doi: 10.1016/j.celrep.2019.01.072.


Sotagliflozin in Combination With Optimized Insulin Therapy in Adults With Type 1 Diabetes: The North American inTandem1 Study.

Buse JB, Garg SK, Rosenstock J, Bailey TS, Banks P, Bode BW, Danne T, Kushner JA, Lane WS, Lapuerta P, McGuire DK, Peters AL, Reed J, Sawhney S, Strumph P.

Diabetes Care. 2018 Sep;41(9):1970-1980. doi: 10.2337/dc18-0343. Epub 2018 Jun 24.


Correction to: Lane et al., Insulin degludec versus insulin glargine U100 for patients with type 1 or type 2 diabetes in the US: a budget impact analysis with rebate tables.

Lane W, Weatherall J, Gundgaard J, Pollock RF.

J Med Econ. 2018 May;21(5):542. doi: 10.1080/13696998.2018.1452510. Epub 2018 Mar 21. No abstract available.


Insulin degludec versus insulin glargine U100 for patients with type 1 or type 2 diabetes in the US: a budget impact analysis with rebate tables.

Lane WS, Weatherall J, Gundgaard J, Pollock RF.

J Med Econ. 2018 Feb;21(2):144-151. doi: 10.1080/13696998.2017.1384383. Epub 2017 Oct 12. Erratum in: J Med Econ. 2018 May;21(5):542.


Efficacy of Liraglutide for Weight Loss Among Patients With Type 2 Diabetes: The SCALE Diabetes Randomized Clinical Trial.

Davies MJ, Bergenstal R, Bode B, Kushner RF, Lewin A, Skjøth TV, Andreasen AH, Jensen CB, DeFronzo RA; NN8022-1922 Study Group.

JAMA. 2015 Aug 18;314(7):687-99. doi: 10.1001/jama.2015.9676. Erratum in: JAMA. 2016 Jan 5;315(1):90.


Histone deacetylase 10 regulates DNA mismatch repair and may involve the deacetylation of MutS homolog 2.

Radhakrishnan R, Li Y, Xiang S, Yuan F, Yuan Z, Telles E, Fang J, Coppola D, Shibata D, Lane WS, Zhang Y, Zhang X, Seto E.

J Biol Chem. 2015 Sep 11;290(37):22795-804. doi: 10.1074/jbc.M114.612945. Epub 2015 Jul 28.


A Phospho-SIM in the Antiviral Protein PML is Required for Its Recruitment to HSV-1 Genomes.

Smith MC, Box AC, Haug JS, Lane WS, Davido DJ.

Cells. 2014 Dec 10;3(4):1131-58. doi: 10.3390/cells3041131.


A signaling network stimulated by β2 integrin promotes the polarization of lytic granules in cytotoxic cells.

Zhang M, March ME, Lane WS, Long EO.

Sci Signal. 2014 Oct 7;7(346):ra96. doi: 10.1126/scisignal.2005629.


Consensus Statement by the American Association of Clinical Endocrinologists/American College of Endocrinology insulin pump management task force.

Grunberger G, Abelseth JM, Bailey TS, Bode BW, Handelsman Y, Hellman R, Jovanovič L, Lane WS, Raskin P, Tamborlane WV, Rothermel C.

Endocr Pract. 2014 May;20(5):463-89. doi: 10.4158/EP14145.PS. No abstract available.


The structure-function relationships of a natural nanoscale photonic device in cuttlefish chromatophores.

Deravi LF, Magyar AP, Sheehy SP, Bell GR, Mäthger LM, Senft SL, Wardill TJ, Lane WS, Kuzirian AM, Hanlon RT, Hu EL, Parker KK.

J R Soc Interface. 2014 Jan 29;11(93):20130942. doi: 10.1098/rsif.2013.0942. Print 2014 Apr 6.


Doc toxin is a kinase that inactivates elongation factor Tu.

Cruz JW, Rothenbacher FP, Maehigashi T, Lane WS, Dunham CM, Woychik NA.

J Biol Chem. 2014 Mar 14;289(11):7788-98. doi: 10.1074/jbc.M113.544429. Epub 2014 Jan 21. Erratum in: J Biol Chem. 2014 Jul 11;289(28):19276.


Immunodepletion plasma proteomics by tripleTOF 5600 and Orbitrap elite/LTQ-Orbitrap Velos/Q exactive mass spectrometers.

Jones KA, Kim PD, Patel BB, Kelsen SG, Braverman A, Swinton DJ, Gafken PR, Jones LA, Lane WS, Neveu JM, Leung HE, Shaffer SA, Leszyk JD, Stanley BA, Fox TE, Stanley A, Hall MJ, Hampel H, South CD, de la Chapelle A, Burt RW, Jones DA, Kopelovich L, Yeung AT.

J Proteome Res. 2013 Oct 4;12(10):4351-65. doi: 10.1021/pr400307u. Epub 2013 Sep 19.


Efficacy and safety of insulin degludec in a flexible dosing regimen vs insulin glargine in patients with type 1 diabetes (BEGIN: Flex T1): a 26-week randomized, treat-to-target trial with a 26-week extension.

Mathieu C, Hollander P, Miranda-Palma B, Cooper J, Franek E, Russell-Jones D, Larsen J, Tamer SC, Bain SC; NN1250-3770 (BEGIN: Flex T1) Trial Investigators.

J Clin Endocrinol Metab. 2013 Mar;98(3):1154-62. doi: 10.1210/jc.2012-3249. Epub 2013 Feb 7.


The effect of long-term use of U-500 insulin via continuous subcutaneous infusion on durability of glycemic control and weight in obese, insulin-resistant patients with type 2 diabetes.

Lane WS, Weinrib SL, Rappaport JM, Hale CB, Farmer LK, Lane RS.

Endocr Pract. 2013 Mar-Apr;19(2):196-201. doi: 10.4158/EP12226.OR.


Serine/threonine acetylation of TGFβ-activated kinase (TAK1) by Yersinia pestis YopJ inhibits innate immune signaling.

Paquette N, Conlon J, Sweet C, Rus F, Wilson L, Pereira A, Rosadini CV, Goutagny N, Weber AN, Lane WS, Shaffer SA, Maniatis S, Fitzgerald KA, Stuart L, Silverman N.

Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12710-5. doi: 10.1073/pnas.1008203109. Epub 2012 Jul 16.


SIRT1 negatively regulates the activities, functions, and protein levels of hMOF and TIP60.

Peng L, Ling H, Yuan Z, Fang B, Bloom G, Fukasawa K, Koomen J, Chen J, Lane WS, Seto E.

Mol Cell Biol. 2012 Jul;32(14):2823-36. doi: 10.1128/MCB.00496-12. Epub 2012 May 14.


Exploring the limit of metazoan thermal tolerance via comparative proteomics: thermally induced changes in protein abundance by two hydrothermal vent polychaetes.

Dilly GF, Young CR, Lane WS, Pangilinan J, Girguis PR.

Proc Biol Sci. 2012 Aug 22;279(1741):3347-56. doi: 10.1098/rspb.2012.0098. Epub 2012 May 2.


Mast cell restricted mouse and human tryptase·heparin complexes hinder thrombin-induced coagulation of plasma and the generation of fibrin by proteolytically destroying fibrinogen.

Prieto-García A, Zheng D, Adachi R, Xing W, Lane WS, Chung K, Anderson P, Hansbro PM, Castells M, Stevens RL.

J Biol Chem. 2012 Mar 9;287(11):7834-44. doi: 10.1074/jbc.M111.325712. Epub 2012 Jan 10.


Health-related quality of life and treatment satisfaction in the Sensor-Augmented Pump Therapy for A1C Reduction 3 (STAR 3) trial.

Rubin RR, Peyrot M; STAR 3 Study Group.

Diabetes Technol Ther. 2012 Feb;14(2):143-51. doi: 10.1089/dia.2011.0162. Epub 2011 Dec 1.


Protein composition of immunoprecipitated synaptic ribbons.

Kantardzhieva A, Peppi M, Lane WS, Sewell WF.

J Proteome Res. 2012 Feb 3;11(2):1163-74. doi: 10.1021/pr2008972. Epub 2011 Dec 12.


SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities.

Peng L, Yuan Z, Ling H, Fukasawa K, Robertson K, Olashaw N, Koomen J, Chen J, Lane WS, Seto E.

Mol Cell Biol. 2011 Dec;31(23):4720-34. doi: 10.1128/MCB.06147-11. Epub 2011 Sep 26.


Successful management of differentiated thyroid cancer in a community-based endocrine practice.

Weinrib SL, Lane WS, Rappaport JM.

Endocr Pract. 2012 Mar-Apr;18(2):170-8. doi: 10.4158/EP11144.OR.


Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

Sang L, Miller JJ, Corbit KC, Giles RH, Brauer MJ, Otto EA, Baye LM, Wen X, Scales SJ, Kwong M, Huntzicker EG, Sfakianos MK, Sandoval W, Bazan JF, Kulkarni P, Garcia-Gonzalo FR, Seol AD, O'Toole JF, Held S, Reutter HM, Lane WS, Rafiq MA, Noor A, Ansar M, Devi AR, Sheffield VC, Slusarski DC, Vincent JB, Doherty DA, Hildebrandt F, Reiter JF, Jackson PK.

Cell. 2011 May 13;145(4):513-28. doi: 10.1016/j.cell.2011.04.019.


Mechanistic analysis of a DNA damage-induced, PTEN-dependent size checkpoint in human cells.

Kim JS, Xu X, Li H, Solomon D, Lane WS, Jin T, Waldman T.

Mol Cell Biol. 2011 Jul;31(13):2756-71. doi: 10.1128/MCB.01323-10. Epub 2011 May 2.


ABRF-PRG07: advanced quantitative proteomics study.

Falick AM, Lane WS, Lilley KS, MacCoss MJ, Phinney BS, Sherman NE, Weintraub ST, Witkowska HE, Yates NA.

J Biomol Tech. 2011 Apr;22(1):21-6.


The ABRF Proteomics Research Group studies: educational exercises for qualitative and quantitative proteomic analyses.

Friedman DB, Andacht TM, Bunger MK, Chien AS, Hawke DH, Krijgsveld J, Lane WS, Lilley KS, MacCoss MJ, Moritz RL, Settlage RE, Sherman NE, Weintraub ST, Witkowska HE, Yates NA, Turck CW.

Proteomics. 2011 Apr;11(8):1371-81. doi: 10.1002/pmic.201000736. Epub 2011 Mar 11.


A peptidomics strategy to elucidate the proteolytic pathways that inactivate peptide hormones.

Tinoco AD, Kim YG, Tagore DM, Wiwczar J, Lane WS, Danial NN, Saghatelian A.

Biochemistry. 2011 Mar 29;50(12):2213-22. doi: 10.1021/bi2000033. Epub 2011 Feb 22.


Traf7, a MyoD1 transcriptional target, regulates nuclear factor-κB activity during myogenesis.

Tsikitis M, Acosta-Alvear D, Blais A, Campos EI, Lane WS, Sánchez I, Dynlacht BD.

EMBO Rep. 2010 Dec;11(12):969-76. doi: 10.1038/embor.2010.154. Epub 2010 Oct 15.


TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary cilia.

Mukhopadhyay S, Wen X, Chih B, Nelson CD, Lane WS, Scales SJ, Jackson PK.

Genes Dev. 2010 Oct 1;24(19):2180-93. doi: 10.1101/gad.1966210.


Effectiveness of sensor-augmented insulin-pump therapy in type 1 diabetes.

Bergenstal RM, Tamborlane WV, Ahmann A, Buse JB, Dailey G, Davis SN, Joyce C, Peoples T, Perkins BA, Welsh JB, Willi SM, Wood MA; STAR 3 Study Group.

N Engl J Med. 2010 Jul 22;363(4):311-20. doi: 10.1056/NEJMoa1002853. Epub 2010 Jun 29. Erratum in: N Engl J Med. 2010 Sep 9;363(11):1092.


The ATDC (TRIM29) protein binds p53 and antagonizes p53-mediated functions.

Yuan Z, Villagra A, Peng L, Coppola D, Glozak M, Sotomayor EM, Chen J, Lane WS, Seto E.

Mol Cell Biol. 2010 Jun;30(12):3004-15. doi: 10.1128/MCB.01023-09. Epub 2010 Apr 5.


A prospective trial of U500 insulin delivered by Omnipod in patients with type 2 diabetes mellitus and severe insulin resistance.

Lane WS, Weinrib SL, Rappaport JM, Przestrzelski T.

Endocr Pract. 2010 Sep-Oct;16(5):778-84. doi: 10.4158/EP10014.OR. Erratum in: Endocr Pract. 2010 Nov-Dec;16(6):1082.


Peptidomics of prolyl endopeptidase in the central nervous system.

Nolte WM, Tagore DM, Lane WS, Saghatelian A.

Biochemistry. 2009 Dec 22;48(50):11971-81. doi: 10.1021/bi901637c.


ATM activates p53 by regulating MDM2 oligomerization and E3 processivity.

Cheng Q, Chen L, Li Z, Lane WS, Chen J.

EMBO J. 2009 Dec 16;28(24):3857-67. doi: 10.1038/emboj.2009.294.


Insulin-stimulated phosphorylation of the Rab GTPase-activating protein TBC1D1 regulates GLUT4 translocation.

Peck GR, Chavez JA, Roach WG, Budnik BA, Lane WS, Karlsson HK, Zierath JR, Lienhard GE.

J Biol Chem. 2009 Oct 30;284(44):30016-23. doi: 10.1074/jbc.M109.035568. Epub 2009 Sep 9.


Two roles for the Drosophila IKK complex in the activation of Relish and the induction of antimicrobial peptide genes.

Ertürk-Hasdemir D, Broemer M, Leulier F, Lane WS, Paquette N, Hwang D, Kim CH, Stöven S, Meier P, Silverman N.

Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9779-84. doi: 10.1073/pnas.0812022106. Epub 2009 Jun 2.


Biomolecular characterization and protein sequences of the Campanian hadrosaur B. canadensis.

Schweitzer MH, Zheng W, Organ CL, Avci R, Suo Z, Freimark LM, Lebleu VS, Duncan MB, Vander Heiden MG, Neveu JM, Lane WS, Cottrell JS, Horner JR, Cantley LC, Kalluri R, Asara JM.

Science. 2009 May 1;324(5927):626-31. doi: 10.1126/science.1165069.


Phylogenomics of unusual histone H2A Variants in Bdelloid rotifers.

Van Doninck K, Mandigo ML, Hur JH, Wang P, Guglielmini J, Milinkovitch MC, Lane WS, Meselson M.

PLoS Genet. 2009 Mar;5(3):e1000401. doi: 10.1371/journal.pgen.1000401. Epub 2009 Mar 6.


High-dose insulin therapy: is it time for U-500 insulin?

Lane WS, Cochran EK, Jackson JA, Scism-Bacon JL, Corey IB, Hirsch IB, Skyler JS.

Endocr Pract. 2009 Jan-Feb;15(1):71-9. Review.


ABRF-PRG05: de novo peptide sequence determination.

Falick AM, Kowalak JA, Lane WS, Phinney BS, Turck CW, Weintraub ST, West KA, Neubert TA.

J Biomol Tech. 2008 Sep;19(4):251-7.


Phosphorylation regulates targeting of cytoplasmic dynein to kinetochores during mitosis.

Whyte J, Bader JR, Tauhata SB, Raycroft M, Hornick J, Pfister KK, Lane WS, Chan GK, Hinchcliffe EH, Vaughan PS, Vaughan KT.

J Cell Biol. 2008 Dec 1;183(5):819-34. doi: 10.1083/jcb.200804114. Epub 2008 Nov 24.


Peptidase substrates via global peptide profiling.

Tagore DM, Nolte WM, Neveu JM, Rangel R, Guzman-Rojas L, Pasqualini R, Arap W, Lane WS, Saghatelian A.

Nat Chem Biol. 2009 Jan;5(1):23-5. doi: 10.1038/nchembio.126. Epub 2008 Nov 16.


Epitope tagging of endogenous genes in diverse human cell lines.

Kim JS, Bonifant C, Bunz F, Lane WS, Waldman T.

Nucleic Acids Res. 2008 Nov;36(19):e127. doi: 10.1093/nar/gkn566. Epub 2008 Sep 10.


System-wide investigation of ErbB4 reveals 19 sites of Tyr phosphorylation that are unusually selective in their recruitment properties.

Kaushansky A, Gordus A, Budnik BA, Lane WS, Rush J, MacBeath G.

Chem Biol. 2008 Aug 25;15(8):808-17. doi: 10.1016/j.chembiol.2008.07.006.


Lysine acetylation can generate highly charged enzymes with increased resistance toward irreversible inactivation.

Shaw BF, Schneider GF, Bilgiçer B, Kaufman GK, Neveu JM, Lane WS, Whitelegge JP, Whitesides GM.

Protein Sci. 2008 Aug;17(8):1446-55. doi: 10.1110/ps.035154.108. Epub 2008 May 1.


Regulation of Ca2+/calmodulin kinase II by a small C-terminal domain phosphatase.

Gangopadhyay SS, Gallant C, Sundberg EJ, Lane WS, Morgan KG.

Biochem J. 2008 Jun 15;412(3):507-16. doi: 10.1042/BJ20071582.


Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65.

Buerki C, Rothgiesser KM, Valovka T, Owen HR, Rehrauer H, Fey M, Lane WS, Hottiger MO.

Nucleic Acids Res. 2008 Mar;36(5):1665-80. doi: 10.1093/nar/gkn003. Epub 2008 Feb 7.


Inhibition of GLUT4 translocation by Tbc1d1, a Rab GTPase-activating protein abundant in skeletal muscle, is partially relieved by AMP-activated protein kinase activation.

Chavez JA, Roach WG, Keller SR, Lane WS, Lienhard GE.

J Biol Chem. 2008 Apr 4;283(14):9187-95. doi: 10.1074/jbc.M708934200. Epub 2008 Feb 7.

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